acyl-CoA dehydrogenase family protein, partial [Pseudomonas sp. GW456-E6]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| ACAD super family | cl09933 | Acyl-CoA dehydrogenase; Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal ... |
10-43 | 4.77e-13 | ||
Acyl-CoA dehydrogenase; Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC) The actual alignment was detected with superfamily member cd01160: Pssm-ID: 447864 [Multi-domain] Cd Length: 372 Bit Score: 60.21 E-value: 4.77e-13
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| Name | Accession | Description | Interval | E-value | ||
| LCAD | cd01160 | Long chain acyl-CoA dehydrogenase; LCAD is an acyl-CoA dehydrogenases (ACAD), which is found ... |
10-43 | 4.77e-13 | ||
Long chain acyl-CoA dehydrogenase; LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer. Pssm-ID: 173849 [Multi-domain] Cd Length: 372 Bit Score: 60.21 E-value: 4.77e-13
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| Acyl-CoA_dh_N | pfam02771 | Acyl-CoA dehydrogenase, N-terminal domain; The N-terminal domain of Acyl-CoA dehydrogenase is ... |
8-43 | 8.38e-09 | ||
Acyl-CoA dehydrogenase, N-terminal domain; The N-terminal domain of Acyl-CoA dehydrogenase is an all-alpha domain. Pssm-ID: 460686 [Multi-domain] Cd Length: 113 Bit Score: 46.30 E-value: 8.38e-09
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| CaiA | COG1960 | Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and ... |
7-43 | 4.82e-06 | ||
Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]; Acyl-CoA dehydrogenase related to the alkylation response protein AidB is part of the Pathway/BioSystem: Fatty acid biosynthesis Pssm-ID: 441563 [Multi-domain] Cd Length: 381 Bit Score: 40.21 E-value: 4.82e-06
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| Name | Accession | Description | Interval | E-value | ||
| LCAD | cd01160 | Long chain acyl-CoA dehydrogenase; LCAD is an acyl-CoA dehydrogenases (ACAD), which is found ... |
10-43 | 4.77e-13 | ||
Long chain acyl-CoA dehydrogenase; LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer. Pssm-ID: 173849 [Multi-domain] Cd Length: 372 Bit Score: 60.21 E-value: 4.77e-13
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| Acyl-CoA_dh_N | pfam02771 | Acyl-CoA dehydrogenase, N-terminal domain; The N-terminal domain of Acyl-CoA dehydrogenase is ... |
8-43 | 8.38e-09 | ||
Acyl-CoA dehydrogenase, N-terminal domain; The N-terminal domain of Acyl-CoA dehydrogenase is an all-alpha domain. Pssm-ID: 460686 [Multi-domain] Cd Length: 113 Bit Score: 46.30 E-value: 8.38e-09
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| CaiA | COG1960 | Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and ... |
7-43 | 4.82e-06 | ||
Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]; Acyl-CoA dehydrogenase related to the alkylation response protein AidB is part of the Pathway/BioSystem: Fatty acid biosynthesis Pssm-ID: 441563 [Multi-domain] Cd Length: 381 Bit Score: 40.21 E-value: 4.82e-06
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| Blast search parameters | ||||
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