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Conserved domains on  [gi|2018986280|ref|WP_208456548|]
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glycosyltransferase [Burkholderia sp. BCC1644]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 223-376 1.06e-49

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


:

Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 165.14  E-value: 1.06e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEAEVRAALDAADAFVL 302
Cdd:pfam00534   5 ILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAGDGEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLPELLKIADVFVL 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2018986280 303 PSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQH 376
Cdd:pfam00534  85 PSRYEGFGIVLLEAMACGLPVIASDVGGPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARKR 158
Glyco_transf_4 super family cl48185
Glycosyltransferase Family 4;
113-190 1.67e-03

Glycosyltransferase Family 4;


The actual alignment was detected with superfamily member pfam13439:

Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 39.05  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 113 VVRWMADRDLHHLHVHFATAGANVGLLARTIAPIGLSLTVHGPDEFDDVDGQHLRAK-----------VRAADLVVCISQ 181
Cdd:pfam13439  63 LRRLLRRERPDVVHAHSPFPLGLAALAARLRLGIPLVVTYHGLFPDYKRLGARLSPLrrllrrlerrlLRRADRVIAVSE 142


                  ....*....
gi 2018986280 182 FARSQLMRL 190
Cdd:pfam13439 143 AVADELRRL 151
 
Name Accession Description Interval E-value
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 223-376 1.06e-49

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 165.14  E-value: 1.06e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEAEVRAALDAADAFVL 302
Cdd:pfam00534   5 ILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAGDGEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLPELLKIADVFVL 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2018986280 303 PSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQH 376
Cdd:pfam00534  85 PSRYEGFGIVLLEAMACGLPVIASDVGGPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARKR 158
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 125-394 1.24e-49

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 171.95  E-value: 1.24e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 125 LHVHFATAGANVGLLARtIAPIGLSLTVHGPDEFDDVDGQHLRAKV--------RAADLVVCISQFARSQLMRLSERAQw 196
Cdd:cd03801    86 VHAHGLLAALLAALLAL-LLGAPLVVTLHGAEPGRLLLLLAAERRLlaraeallRRADAVIAVSEALRDELRALGGIPP- 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 197 RKLQVCRLGVAEHAGSRMPARGAATE-----LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASlRERVR 271
Cdd:cd03801   164 EKIVVIPNGVDLERFSPPLRRKLGIPpdrpvLLFVGRLSPRKGVDLLLEALAKLLRRGPDVRLVIVGGDGPLRA-ELEEL 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 272 QLGLGEHVCFAGALNEAEVRAALDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADA 351
Cdd:cd03801   243 ELGLGDRVRFLGFVPDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLPEVVEDGEGGLVVPPDDVEA 322

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2018986280 352 LAGSIRTLLEDADARRRFAEAGRQHLREAFDLQQNVARLASLF 394
Cdd:cd03801   323 LADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLY 365
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
 224-394 1.19e-31

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 123.68  E-value: 1.19e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 224 LCVGRLTAAKGQHVLLDACARLRAQGC----AFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGalNEAEVRAALDAADA 299
Cdd:TIGR03088 198 GTVGRLQAVKDQPTLVRAFALLVRQLPegaeRLRLVIVGDGPARGACEQMVRAAGLAHLVWLPG--ERDDVPALMQALDL 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 300 FVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLRE 379
Cdd:TIGR03088 276 FVLPSLAEGISNTILEAMASGLPVIATAVGGNPELVQHGVTGALVPPGDAVALARALQPYVSDPAARRAHGAAGRARAEQ 355

                         170
                  ....*....|....*
gi 2018986280 380 AFDLQQNVARLASLF 394
Cdd:TIGR03088 356 QFSINAMVAAYAGLY 370
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 290-394 6.02e-30

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 112.01  E-value: 6.02e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 290 VRAALDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRF 369
Cdd:COG0438    14 LEALLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRL 93

                          90       100
                  ....*....|....*....|....*
gi 2018986280 370 AEAGRQHLREAFDLQQNVARLASLF 394
Cdd:COG0438    94 GEAARERAEERFSWEAIAERLLALY 118
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 223-375 4.17e-23

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 100.94  E-value: 4.17e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGqhvlLDACARLRAQGCAFRLTLVGQGSDeaslRERVRQLGLGEHVCFAGALNEAEVRAALDAADAFVL 302
Cdd:PLN02871  266 IVYVGRLGAEKN----LDFLKRVMERLPGARLAFVGDGPY----REELEKMFAGTPTVFTGMLQGDELSQAYASGDVFVM 337

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2018986280 303 PSLAEGIPVVLMEAMAAGVPCISCPVNGIPELI---EDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQ 375
Cdd:PLN02871  338 PSESETLGFVVLEAMASGVPVVAARAGGIPDIIppdQEGKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAARE 413
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 267-373 2.32e-08

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 55.71  E-value: 2.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 267 RERVRQLGLGEHVCFAGALNEAEVraaLDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIED--------G 338
Cdd:NF038011  357 RSLVASLGLQDKVKFLGFQKIDDL---LPQVGLMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQLIEGldeedralG 433

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2018986280 339 KSGLLASPGDADALAGSIRTLLEDADARRRFAEAG 373
Cdd:NF038011  434 AAGEVVAIADPQALARAALDLLRDPQRWQAAQAAG 468
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
113-190 1.67e-03

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 39.05  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 113 VVRWMADRDLHHLHVHFATAGANVGLLARTIAPIGLSLTVHGPDEFDDVDGQHLRAK-----------VRAADLVVCISQ 181
Cdd:pfam13439  63 LRRLLRRERPDVVHAHSPFPLGLAALAARLRLGIPLVVTYHGLFPDYKRLGARLSPLrrllrrlerrlLRRADRVIAVSE 142


                  ....*....
gi 2018986280 182 FARSQLMRL 190
Cdd:pfam13439 143 AVADELRRL 151
 
Name Accession Description Interval E-value
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 223-376 1.06e-49

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 165.14  E-value: 1.06e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEAEVRAALDAADAFVL 302
Cdd:pfam00534   5 ILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAGDGEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLPELLKIADVFVL 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2018986280 303 PSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQH 376
Cdd:pfam00534  85 PSRYEGFGIVLLEAMACGLPVIASDVGGPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARKR 158
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 125-394 1.24e-49

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 171.95  E-value: 1.24e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 125 LHVHFATAGANVGLLARtIAPIGLSLTVHGPDEFDDVDGQHLRAKV--------RAADLVVCISQFARSQLMRLSERAQw 196
Cdd:cd03801    86 VHAHGLLAALLAALLAL-LLGAPLVVTLHGAEPGRLLLLLAAERRLlaraeallRRADAVIAVSEALRDELRALGGIPP- 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 197 RKLQVCRLGVAEHAGSRMPARGAATE-----LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASlRERVR 271
Cdd:cd03801   164 EKIVVIPNGVDLERFSPPLRRKLGIPpdrpvLLFVGRLSPRKGVDLLLEALAKLLRRGPDVRLVIVGGDGPLRA-ELEEL 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 272 QLGLGEHVCFAGALNEAEVRAALDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADA 351
Cdd:cd03801   243 ELGLGDRVRFLGFVPDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLPEVVEDGEGGLVVPPDDVEA 322

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2018986280 352 LAGSIRTLLEDADARRRFAEAGRQHLREAFDLQQNVARLASLF 394
Cdd:cd03801   323 LADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLY 365
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 6-391 1.23e-42

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 153.30  E-value: 1.23e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280   6 LVSRYPAVSHT----FILREVRALRALGATVAVASVNAPDRPAQRMTDAERDEAHATYYVKRdgaagalRAVLHCVLRH- 80
Cdd:cd03798     4 LTNIYPNANSPgrgiFVRRQVRALSRRGVDVEVLAPAPWGPAAARLLRKLLGEAVPPRDGRR-------LLPLKPRLRLl 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280  81 PGGCLRALATSLTLGRgarrlyalaylaeaamvvRWMADRdlhhLHVHFATAGANVGLLARTIAPIGLSLTVHGPD--EF 158
Cdd:cd03798    77 APLRAPSLAKLLKRRR------------------RGPPDL----IHAHFAYPAGFAAALLARLYGVPYVVTEHGSDinVF 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 159 DDVDGQH--LRAKVRAADLVVCISQFARSQLMRLSERAQwrKLQVCRLGVAEH----AGSRMPARGAATELLCVGRLTAA 232
Cdd:cd03798   135 PPRSLLRklLRWALRRAARVIAVSKALAEELVALGVPRD--RVDVIPNGVDPArfqpEDRGLGLPLDAFVILFVGRLIPR 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 233 KGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEAEVRAALDAADAFVLPSLAEGIPVV 312
Cdd:cd03798   213 KGIDLLLEAFARLAKARPDVVLLIVGDGPLREALRALAEDLGLGDRVTFTGRLPHEQVPAYYRACDVFVLPSRHEGFGLV 292

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2018986280 313 LMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRfAEAGRQHLREAFDLQQNVARLA 391
Cdd:cd03798   293 LLEAMACGLPVVATDVGGIPEVVGDPETGLLVPPGDADALAAALRRALAEPYLREL-GEAARARVAERFSWVKAADRIA 370
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 125-390 2.49e-41

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 149.67  E-value: 2.49e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 125 LHVHFATAGANVGLLARTIAPIGLSLTVHGPdEFDDVDGQHLRAKV--------RAADLVVCISQFARSQLMRLSERAQW 196
Cdd:cd03808    85 VHCHTPKPGILGRLAARLAGVPKVIYTVHGL-GFVFTEGKLLRLLYllleklalLFTDKVIFVNEDDRDLAIKKGIIKKK 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 197 RKLQVCRLGVAEHAGSRMP--ARGAATELLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLG 274
Cdd:cd03808   164 KTVLIPGSGVDLDRFQYSPesLPSEKVVFLFVARLLKDKGIDELIEAAKILKKKGPNVRFLLVGDGELENPSEILIEKLG 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 275 LGEHVCFAGALNEaeVRAALDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAG 354
Cdd:cd03808   244 LEGRIEFLGFRSD--VPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDGVNGFLVPPGDVEALAD 321

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2018986280 355 SIRTLLEDADARRRFAEAGRQHLREAFDLQQNVARL 390
Cdd:cd03808   322 AIEKLIEDPELRKEMGEAARKRVEEKFDEEKVVNKL 357
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 167-381 6.75e-41

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 148.28  E-value: 6.75e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 167 RAKVRAADLVVCISQFARSQLMRLsERAQWRKLQVCRLGVaEHAGSRMPAR-------GAATELLCVGRLTAAKGQHVLL 239
Cdd:cd03811   130 LKLYKKADKIVCVSKGIKEDLIRL-GPSPPEKIEVIYNPI-DIDRIRALAKepilnepEDGPVILAVGRLDPQKGHDLLI 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 240 DACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGAlnEAEVRAALDAADAFVLPSLAEGIPVVLMEAMAA 319
Cdd:cd03811   208 EAFAKLRKKYPDVKLVILGDGPLREELEKLAKELGLAERVIFLGF--QSNPYPYLKKADLFVLSSRYEGFPNVLLEAMAL 285

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2018986280 320 GVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDAD--ARRRFAEAGRQHLREAF 381
Cdd:cd03811   286 GTPVVSTDCPGPREILDDGENGLLVPDGDAAALAGILAALLQKKLdaALRERLAKAQEAVFREY 349
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
 2-383 1.77e-40

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 147.21  E-value: 1.77e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280   2 RLAYLVSRYPAVSHTFILREVRALRALGATVAVASVNaPDRPAQRMTDAERdeahatYYVkrdgaagalravlhcvlrhp 81
Cdd:cd03799     1 KIAFIVDEFPVLSETFILNQITGLIDRGHEVDIYAVN-PGDLVKRHPDVEK------YNV-------------------- 53

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280  82 ggclrALATSLTLGRGARRLYALaylaeaamvvrwmadrDLhhLHVHFATAGANVGLLARTIAPIGLSLTV-HGPD---- 156
Cdd:cd03799    54 -----PSLNLLYAIVGLNKKGAY----------------DI--IHCQFGPLGALGALLRRLKVLKGKLVTSfRGYDismy 110

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 157 --EFDDVDGQHLRAKvraADLVVCISQFARSQLMRLSERAQwrKLQVCRLGVA----EHAGSRMPARGAaTELLCVGRLT 230
Cdd:cd03799   111 viLEGNKVYPQLFAQ---GDLFLPNCELFKHRLIALGCDEK--KIIVHRSGIDcnkfRFKPRYLPLDGK-IRILTVGRLT 184

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 231 AAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEAEVRAALDAADAFVLPSLA---- 306
Cdd:cd03799   185 EKKGLEYAIEAVAKLAQKYPNIEYQIIGDGDLKEQLQQLIQELNIGDCVKLLGWKPQEEIIEILDEADIFIAPSVTaadg 264

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2018986280 307 --EGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREAFDL 383
Cdd:cd03799   265 dqDGPPNTLKEAMAMGLPVISTEHGGIPELVEDGVSGFLVPERDAEAIAEKLTYLIEHPAIWPEMGKAGRARVEEEYDI 343
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
223-362 2.22e-40

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 140.34  E-value: 2.22e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTA-AKGQHVLLDACARLRAQGCAFRLTLVGQGsDEASLRERVRqlGLGEHVCFAGALNEaeVRAALDAADAFV 301
Cdd:pfam13692   4 ILFVGRLHPnVKGVDYLLEAVPLLRKRDNDVRLVIVGDG-PEEELEELAA--GLEDRVIFTGFVED--LAELLAAADVFV 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2018986280 302 LPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIeDGKSGLLASPGDADALAGSIRTLLED 362
Cdd:pfam13692  79 LPSLYEGFGLKLLEAMAAGLPVVATDVGGIPELV-DGENGLLVPPGDPEALAEAILRLLED 138
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 9-390 7.91e-40

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 145.67  E-value: 7.91e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280   9 RYPAVSHTFILREVRALRALgatvavasvnapdrpaqrmtdaerdeaHATYYVKRDGAAGALRAVlHCVLRHPGGCLRAL 88
Cdd:cd05844     8 VLLPVSETFIREQASGLRRY---------------------------RPTFVGCRRLAPAPFDGV-ALRALGGSGPLRWL 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280  89 --ATSLTLGRGARRLYALaylaeaamvvrwmADRDLHHLHVHFATAGANVGLLARTIApIGLSLTVHGPDEFDD------ 160
Cdd:cd05844    60 rqMAQRLLGWSAPRLGGA-------------AGLAPALVHAHFGRDGVYALPLARALG-VPLVVTFHGFDITTSrawlaa 125

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 161 ------VDGQHLRAKVRAADLVVCISQFARSQLMRLSERAqwRKLQVCRLGVAEHAGSRMPARGAATELLCVGRLTAAKG 234
Cdd:cd05844   126 spgwpsQFQRHRRALQRPAALFVAVSGFIRDRLLARGLPA--ERIHVHYIGIDPAKFAPRDPAERAPTILFVGRLVEKKG 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 235 QHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGlgeHVCFAGALNEAEVRAALDAADAFVLPSL------AEG 308
Cdd:cd05844   204 CDVLIEAFRRLAARHPTARLVIAGDGPLRPALQALAAALG---RVRFLGALPHAEVQDWMRRAEIFCLPSVtaasgdSEG 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 309 IPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREAFDLQQNVA 388
Cdd:cd05844   281 LGIVLLEAAACGVPVVSSRHGGIPEAILDGETGFLVPEGDVDALADALQALLADRALADRMGGAARAFVCEQFDIRVQTA 360


                  ..
gi 2018986280 389 RL 390
Cdd:cd05844   361 KL 362
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 225-394 8.58e-39

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 142.84  E-value: 8.58e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 225 CVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGalNEAEVRAALDAADAFVLPS 304
Cdd:cd03807   195 IVGRLHPVKDHSDLLRAAALLVETHPDLRLLLVGRGPERPNLERLLLELGLEDRVHLLG--ERSDVPALLPAMDIFVLSS 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 305 LAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGkSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREAFDLQ 384
Cdd:cd03807   273 RTEGFPNALLEAMACGLPVVATDVGGAAELVDDG-TGFLVPAGDPQALADAIRALLEDPEKRARLGRAARERIANEFSID 351

                         170
                  ....*....|
gi 2018986280 385 QNVARLASLF 394
Cdd:cd03807   352 AMVRRYETLY 361
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 223-384 1.14e-36

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 136.98  E-value: 1.14e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGalNEAEVRAALDAADAFVL 302
Cdd:cd03820   184 ILAVGRLTYQKGFDLLIEAWALIAKKHPDWKLRIYGDGPEREELEKLIDKLGLEDRVKLLG--PTKNIAEEYANSSIFVL 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 303 PSLAEGIPVVLMEAMAAGVPCIS--CPVnGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRqHLREA 380
Cdd:cd03820   262 SSRYEGFPMVLLEAMAYGLPIISfdCPT-GPSEIIEDGENGLLVPNGDVDALAEALLRLMEDEELRKKMGKNAR-KNAER 339


                  ....
gi 2018986280 381 FDLQ 384
Cdd:cd03820   340 FSIE 343
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 113-381 3.20e-34

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 130.17  E-value: 3.20e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 113 VVRWMADRDLHHLHVHFATAGAnVGLLARTIAPIGLSLTVHGPDEFDDVDGQHLRAKVRAADLVVCISQFARSQLMRLSE 192
Cdd:cd03819    68 LARLIRRERIDLIHAHSRAPAW-LGWLASRLTGVPLVTTVHGSYLATYHPKDFALAVRARGDRVIAVSELVRDHLIEALG 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 193 RAQwRKLQVCRLGV------AEHAGSRMPARGAATE---LLCVGRLTAAKGQHVLLDACARLRAQGCaFRLTLVGQGSDE 263
Cdd:cd03819   147 VDP-ERIRVIPNGVdtdrfpPEAEAEERAQLGLPEGkpvVGYVGRLSPEKGWLLLVDAAAELKDEPD-FRLLVAGDGPER 224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 264 ASLRERVRQLGLGEHVCFAGALNEaeVRAALDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLL 343
Cdd:cd03819   225 DEIRRLVERLGLRDRVTFTGFRED--VPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGAREIVVHGRTGLL 302

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 2018986280 344 ASPGDADALAGSIRTLLEDADARRRFAEAGRQ--HLREAF 381
Cdd:cd03819   303 VPPGDAEALADAIRAAKLLPEAREKLQAAAALteAVRELL 342
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 166-391 6.36e-34

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 129.79  E-value: 6.36e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 166 LRAKVRAADLVVCISQFARSQLMR-LSERAqwRKLQVCRLGVAEHAGSRMPARGAATE-------LLCVGRLTAAKGQHV 237
Cdd:cd03809   132 LPISLRRADAIITVSEATRDDIIKfYGVPP--EKIVVIPLGVDPSFFPPESAAVLIAKyllpepyFLYVGTLEPRKNHER 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 238 LLDACARLRAQGCAFRLTLVGQGSDE-ASLRERVRQLGLGEHVCFAGALNEAEVRAALDAADAFVLPSLAE--GIPVVlm 314
Cdd:cd03809   210 LLKAFALLKKQGGDLKLVIVGGKGWEdEELLDLVKKLGLGGRVRFLGYVSDEDLPALYRGARAFVFPSLYEgfGLPVL-- 287

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2018986280 315 EAMAAGVPCISCPVNGIPELIEDgkSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREaFDLQQNVARLA 391
Cdd:cd03809   288 EAMACGTPVIASNISVLPEVAGD--AALYFDPLDPESIADAILRLLEDPSLREELIRKGLERAKK-FSWEKTAEKTL 361
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 223-380 1.60e-33

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 128.94  E-value: 1.60e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAQGcAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEAEVRAALDAADAFVL 302
Cdd:cd03817   204 LLYVGRLAKEKNIDFLLRAFAELKKEP-NIKLVIVGDGPEREELKELARELGLADKVIFTGFVPREELPEYYKAADLFVF 282

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2018986280 303 PSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRtLLEDADARRRFAEAGRQHLREA 380
Cdd:cd03817   283 ASTTETQGLVYLEAMAAGLPVVAAKDPAASELVEDGENGFLFEPNDETLAEKLLH-LRENLELLRKLSKNAEISAREF 359
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
 224-394 1.19e-31

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 123.68  E-value: 1.19e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 224 LCVGRLTAAKGQHVLLDACARLRAQGC----AFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGalNEAEVRAALDAADA 299
Cdd:TIGR03088 198 GTVGRLQAVKDQPTLVRAFALLVRQLPegaeRLRLVIVGDGPARGACEQMVRAAGLAHLVWLPG--ERDDVPALMQALDL 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 300 FVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLRE 379
Cdd:TIGR03088 276 FVLPSLAEGISNTILEAMASGLPVIATAVGGNPELVQHGVTGALVPPGDAVALARALQPYVSDPAARRAHGAAGRARAEQ 355

                         170
                  ....*....|....*
gi 2018986280 380 AFDLQQNVARLASLF 394
Cdd:TIGR03088 356 QFSINAMVAAYAGLY 370
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 121-382 9.27e-31

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 121.30  E-value: 9.27e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 121 DLHHLHVHFATAGANVGLLARTI--APIGLSLTVHGPDEfdDVDGQH------LRAKVRAADLVVCISQFARSQLMRLSE 192
Cdd:cd04962    84 KLDVLHAHYAIPHASCAYLAREIlgEKIPIVTTLHGTDI--TLVGYDpslqpaVRFSINKSDRVTAVSSSLRQETYELFD 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 193 RAqwRKLQV------CRLGVAEHAGSRMPARGAATE---LLCVGRLTAAKGQHVLLDACARLRAQGCAfRLTLVGQGSDE 263
Cdd:cd04962   162 VD--KDIEVihnfidEDVFKRKPAGALKRRLLAPPDekvVIHVSNFRPVKRIDDVVRVFARVRRKIPA-KLLLVGDGPER 238

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 264 ASLRERVRQLGLGEHVCFAGalNEAEVRAALDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLL 343
Cdd:cd04962   239 VPAEELARELGVEDRVLFLG--KQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGIPEVVKHGETGFL 316

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2018986280 344 ASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREAFD 382
Cdd:cd04962   317 SDVGDVDAMAKSALSILEDDELYNRMGRAARKRAAERFD 355
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 290-394 6.02e-30

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 112.01  E-value: 6.02e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 290 VRAALDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRF 369
Cdd:COG0438    14 LEALLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRL 93

                          90       100
                  ....*....|....*....|....*
gi 2018986280 370 AEAGRQHLREAFDLQQNVARLASLF 394
Cdd:COG0438    94 GEAARERAEERFSWEAIAERLLALY 118
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 224-381 6.09e-29

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 115.83  E-value: 6.09e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 224 LCVGRLTAAKGQHVLLDAcarlrAQGCAFRLTLVGQGSDEASLRERVrQLGLGEHVCFAGALNEAEVRAALDAADAFVLP 303
Cdd:cd03795   195 LFIGRLVYYKGLDYLIEA-----AQYLNYPIVIGGEGPLKPDLEAQI-ELNLLDNVKFLGRVDDEEKVIYLHLCDVFVFP 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 304 SL--AEGIPVVLMEAMAAGVPCISCPVN-GIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREA 380
Cdd:cd03795   269 SVlrSEAFGIVLLEAMMCGKPVISTNIGtGVPYVNNNGETGLVVPPKDPDALAEAIDKLLSDEELRESYGENAKKRFEEL 348


                  .
gi 2018986280 381 F 381
Cdd:cd03795   349 F 349
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 223-392 3.59e-28

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 114.26  E-value: 3.59e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEAS------LRERVRQLGLGEHVCFAGALNEAEVRAALDA 296
Cdd:cd03800   223 VLALGRLDPRKGIDTLVRAFAQLPELRELANLVLVGGPSDDPLsmdreeLAELAEELGLIDRVRFPGRVSRDDLPELYRA 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 297 ADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQH 376
Cdd:cd03800   303 ADVFVVPSLYEPFGLTAIEAMACGTPVVATAVGGLQDIVRDGRTGLLVDPHDPEALAAALRRLLDDPALWQRLSRAGLER 382

                         170
                  ....*....|....*.
gi 2018986280 377 LREAFDLQQNVARLAS 392
Cdd:cd03800   383 ARAHYTWESVADQLLT 398
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 72-343 1.27e-26

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 106.72  E-value: 1.27e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280  72 AVLHCVLRHPGGCLRALATSLTLGRGARRLYALAYLAEAAMVVRW---MADRDLHHLHVHFATAGANVGLLARTIAPIGL 148
Cdd:cd01635     2 LLVTGEYPPLRGGLELHVRALARALAALGHEVTVLALLLLALRRIlkkLLELKPDVVHAHSPHAAALAALLAARLLGIPI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 149 SLTVHGPDEFDDVDGQHLRAKVRAADLVVCIsqfarsqlmrlseraqwrklqvcrlgvaehagsrmpargaateLLCVGR 228
Cdd:cd01635    82 VVTVHGPDSLESTRSELLALARLLVSLPLAD-------------------------------------------KVSVGR 118

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 229 LTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEAEVRAALDA-ADAFVLPSLAE 307
Cdd:cd01635   119 LVPEKGIDLLLEALALLKARLPDLVLVLVGGGGEREEEEALAAALGLLERVVIIGGLVDDEVLELLLAaADVFVLPSRSE 198

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2018986280 308 GIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLL 343
Cdd:cd01635   199 GFGLVLLEAMAAGKPVIATDVGGIPEFVVDGENGLL 234
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 166-376 3.09e-26

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 108.54  E-value: 3.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 166 LRAKVRAADLVVCISQFarsqLMRLSERAQWRKLQVCRLGV------AEHAGSRMPARGAATE---LLCVGRLTAAKGQH 236
Cdd:cd03814   139 LRWFHNPFDTTLVPSPS----IARELEGHGFERVRLWPRGVdtelfhPSRRDAALRRRLGPPGrplLLYVGRLAPEKNLE 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 237 VLLDACARLrAQGCAFRLTLVGQGSDEASLRERvrqlglGEHVCFAGALNEAEVRAALDAADAFVLPSLAEGIPVVLMEA 316
Cdd:cd03814   215 ALLDADLPL-AASPPVRLVVVGDGPARAELEAR------GPDVIFTGFLTGEELARAYASADVFVFPSRTETFGLVVLEA 287

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 317 MAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQH 376
Cdd:cd03814   288 MASGLPVVAADAGGPRDIVRPGGTGALVEPGDAAAFAAALRALLEDPELRRRMAARARAE 347
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 203-376 3.17e-26

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 108.19  E-value: 3.17e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 203 RLGVAEHAGSRMPAR-------GAATELLCVGRLTAAKGQHVLLDACARLRAQGcaFRLTLVGQGSDEaslreRVRQLGL 275
Cdd:cd03823   167 RISVIPNAVEPDLAPpprrrpgTERLRFGYIGRLTEEKGIDLLVEAFKRLPRED--IELVIAGHGPLS-----DERQIEG 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 276 GEHVCFAGALNEAEVRAALDAADAFVLPSL-AEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAG 354
Cdd:cd03823   240 GRRIAFLGRVPTDDIKDFYEKIDVLVVPSIwPEPFGLVVREAIAAGLPVIASDLGGIAELIQPGVNGLLFAPGDAEDLAA 319

                         170       180
                  ....*....|....*....|..
gi 2018986280 355 SIRTLLEDADARRRFAEAGRQH 376
Cdd:cd03823   320 AMRRLLTDPALLERLRAGAEPP 341
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 112-389 8.52e-25

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 105.88  E-value: 8.52e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 112 MVVRWMADRDLHHL---HVHFATAGANVGLLARTIAPIGLSLTVHG----------PDEFDDVDGQ---------HL-RA 168
Cdd:cd03813   161 LFKLAIAADDLPEAdlyHSVSTGYAGLLGALARHRRGIPFLLTEHGiytrerkieiLQSTWIMGYIkklwirffeRLgKL 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 169 KVRAADLVVCISQFARSQLMRLSerAQWRKLQVCRLGV--AEHAGSRMPARGAATELL-CVGRLTAAKGQHVLLDACARL 245
Cdd:cd03813   241 AYQQADKIISLYEGNRRRQIRLG--ADPDKTRVIPNGIdiQRFAPAREERPEKEPPVVgLVGRVVPIKDVKTFIRAFKLV 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 246 RAQGCAFRLTLVGqGSDE-----ASLRERVRQLGLGEHVCFAGALNEAEVRAALDAadaFVLPSLAEGIPVVLMEAMAAG 320
Cdd:cd03813   319 RRAMPDAEGWLIG-PEDEdpeyaQECKRLVASLGLENKVKFLGFQNIKEYYPKLGL---LVLTSISEGQPLVILEAMASG 394

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2018986280 321 VPCISCPVNGIPELIED-----GKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREAFDLQQNVAR 389
Cdd:cd03813   395 VPVVATDVGSCRELIYGaddalGQAGLVVPPADPEALAEALIKLLRDPELRQAFGEAGRKRVEKYYTLEGMIDS 468
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 217-375 8.21e-24

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 101.68  E-value: 8.21e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 217 RGAATELLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSD-EASLRERVRQLGLGEHVCFAGALNEAEVRAALD 295
Cdd:cd03821   201 LEDRRIILFLGRIHPKKGLDLLIRAARKLAEQGRDWHLVIAGPDDGaYPAFLQLQSSLGLGDRVTFTGPLYGEAKWALYA 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 296 AADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGkSGLLASPgDADALAGSIRTLLEDADARRRFAEAGRQ 375
Cdd:cd03821   281 SADLFVLPSYSENFGNVVAEALACGLPVVITDKCGLSELVEAG-CGVVVDP-NVSSLAEALAEALRDPADRKRLGEMARR 358
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 223-375 4.17e-23

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 100.94  E-value: 4.17e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGqhvlLDACARLRAQGCAFRLTLVGQGSDeaslRERVRQLGLGEHVCFAGALNEAEVRAALDAADAFVL 302
Cdd:PLN02871  266 IVYVGRLGAEKN----LDFLKRVMERLPGARLAFVGDGPY----REELEKMFAGTPTVFTGMLQGDELSQAYASGDVFVM 337

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2018986280 303 PSLAEGIPVVLMEAMAAGVPCISCPVNGIPELI---EDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQ 375
Cdd:PLN02871  338 PSESETLGFVVLEAMASGVPVVAARAGGIPDIIppdQEGKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAARE 413
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 233-389 3.29e-22

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 97.02  E-value: 3.29e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 233 KGQHVLLDACARLrAQGCAFRLTLVGqgsdeaSLRERVRQLGlGEHVCFAGALNEAEVRAALDAADAFVLPSLAEGIPVV 312
Cdd:cd03825   208 KGFDELIEALKLL-ATKDDLLLVVFG------KNDPQIVILP-FDIISLGYIDDDEQLVDIYSAADLFVHPSLADNLPNT 279

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2018986280 313 LMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREAFDlQQNVAR 389
Cdd:cd03825   280 LLEAMACGTPVVAFDTGGSPEIVQHGVTGYLVPPGDVQALAEAIEWLLANPKERESLGERARALAENHFD-QRVQAQ 355
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 171-391 4.46e-21

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 93.95  E-value: 4.46e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 171 RAADLVVCISQFARSQLMRLSERAqwRKLQVCRLGVAEHAGSRMPARGAATELLCVGRLTA--------AKGQHVLLDAC 242
Cdd:cd03794   162 RLADAIIVLSPGLKEYLLRKGVPK--EKIIVIPNWADLEEFKPPPKDELRKKLGLDDKFVVvyagnigkAQGLETLLEAA 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 243 ARLRAQGCAfRLTLVGQGSDEASLRERVRQLGLgEHVCFAGALNEAEVRAALDAADAFVLP-----SLAEGIPVVLMEAM 317
Cdd:cd03794   240 ERLKRRPDI-RFLFVGDGDEKERLKELAKARGL-DNVTFLGRVPKEEVPELLSAADVGLVPlkdnpANRGSSPSKLFEYM 317

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2018986280 318 AAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREAFDLQQNVARLA 391
Cdd:cd03794   318 AAGKPILASDDGGSDLAVEINGCGLVVEPGDPEALADAILELLDDPELRRAMGENGRELAEEKFSREKLADRLL 391
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
 223-397 7.03e-19

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 87.38  E-value: 7.03e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSD---EASL--RERVRQLGLGE--HVCFAGAlNEAEVRAALD 295
Cdd:cd03792   200 ILQVARFDPSKDPLGVIDAYKLFKRRAEEPQLVICGHGAVddpEGSVvyEEVMEYAGDDHdiHVLRLPP-SDQEINALQR 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 296 AADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALagSIRTLLEDADARRRFAEAGRQ 375
Cdd:cd03792   279 AATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIPLQVIDGETGFLVNSVEGAAV--RILRLLTDPELRRKMGLAARE 356

                         170       180
                  ....*....|....*....|..
gi 2018986280 376 HLREAFDLQQNVARLASLFVAL 397
Cdd:cd03792   357 HVRDNFLITGNLRAWLYLIAKL 378
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
 226-376 1.17e-18

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 86.20  E-value: 1.17e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 226 VGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEaeVRAALDAADAFVLPSL 305
Cdd:cd04949   166 ISRLAPEKQLDHLIEAVAKAVKKVPEITLDIYGYGEEREKLKKLIEELHLEDNVFLKGYHSN--LDQEYQDAYLSLLTSQ 243

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2018986280 306 AEGIPVVLMEAMAAGVPCISCPVN-GIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQH 376
Cdd:cd04949   244 MEGFGLTLMEAIGHGLPVVSYDVKyGPSELIEDGENGYLIEKNNIDALADKIIELLNDPEKLQQFSEESYKI 315
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
 226-324 3.42e-18

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 85.03  E-value: 3.42e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 226 VGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEAEvrAALDAADAFVLPSL 305
Cdd:cd03812   197 VGRFNEQKNHSFLIDIFEELKKKNPNVKLVLVGEGELKEKIKEKVKELGLEDKVIFLGFRNDVS--EILSAMDVFLFPSL 274

                          90
                  ....*....|....*....
gi 2018986280 306 AEGIPVVLMEAMAAGVPCI 324
Cdd:cd03812   275 YEGLPLVAVEAQASGLPCL 293
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 223-383 7.21e-17

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 81.34  E-value: 7.21e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALneAEVRAALDAADAFVL 302
Cdd:cd04951   191 ILNVGRLTEAKDYPNLLLAISELILSKNDFKLLIAGDGPLRNELERLICNLNLVDRVILLGQI--SNISEYYNAADLFVL 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 303 PSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDgkSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREAFD 382
Cdd:cd04951   269 SSEWEGFGLVVAEAMACERPVVATDAGGVAEVVGD--HNYVVPVSDPQLLAEKIKEIFDMSDEERDILGNKNEYIAKNFS 346


                  .
gi 2018986280 383 L 383
Cdd:cd04951   347 I 347
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
 172-389 2.04e-16

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 80.48  E-value: 2.04e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 172 AADLVVCISQFARSQLmrlseRAQWR-KLQVCRLGVAEHAGSrmPARGAATELLCVGRLTA--------------AKGQH 236
Cdd:cd03818   158 QADLGVTPTRWQRSLF-----PAAYRdRISVIHDGVDTDRLA--PDPAARLRLLNGTELKAgdpvityvarnlepYRGFH 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 237 VLLDACARLRAQGCAFRLTLVGQGS--------DEASLRER-VRQLGLG-EHVCFAGALNEAEVRAALDAADAFVLPSLa 306
Cdd:cd03818   231 VFMRALPRIQARRPDARVVVVGGDGvsygspppDGGSWKQKmLAELGVDlERVHFVGKVPYDQYVRLLQLSDAHVYLTY- 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 307 egiPVV----LMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLEDADARRRFAEAGRQHLREAFD 382
Cdd:cd03818   310 ---PFVlswsLLEAMACGCPVIGSDTAPVREVIRDGRNGLLVDFFDPDALAAAVLELLEDPDRAAALRRAARRTVERSDS 386


                  ....*..
gi 2018986280 383 LQQNVAR 389
Cdd:cd03818   387 LDVCLAR 393
PRK09922 PRK09922
lipopolysaccharide 1,6-galactosyltransferase;
215-356 2.81e-16

lipopolysaccharide 1,6-galactosyltransferase;


Pssm-ID: 182148 [Multi-domain]  Cd Length: 359  Bit Score: 79.37  E-value: 2.81e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 215 PARGAATELLCVGRLTAAKGQHV--LLDACARLRAQgcaFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNE--AEV 290
Cdd:PRK09922  175 PERDKPAVFLYVGRLKFEGQKNVkeLFDGLSQTTGE---WQLHIIGDGSDFEKCKAYSRELGIEQRIIWHGWQSQpwEVV 251

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2018986280 291 RAALDAADAFVLPSLAEGIPVVLMEAMAAGVPCIS--CPvNGIPELIEDGKSGLLASPGDADALAGSI 356
Cdd:PRK09922  252 QQKIKNVSALLLTSKFEGFPMTLLEAMSYGIPCISsdCM-SGPRDIIKPGLNGELYTPGNIDEFVGKL 318
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
 198-386 2.90e-13

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 70.95  E-value: 2.90e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 198 KLQVCRLGVAEHAGSRMPARGAATELLCVGRLTAAKGQHVLLDACARLRAQGCAFRL--TLVGQGSDEASLRERVRQLGL 275
Cdd:cd04946   202 KIFVSRLGVSDKEQYSKVKKEGDLRLVSCSSIVPVKRIDLIIETLNSLCVAHPSICIswTHIGGGPLKERLEKLAENKLE 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 276 GEHVCFAGALNEAEVRA--ALDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLL----ASPGDa 349
Cdd:cd04946   282 NVKVNFTGEVSNKEVKQlyKENDVDVFVNVSESEGIPVSIMEAISFGIPVIATNVGGTREIVENETNGLLldkdPTPNE- 360

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2018986280 350 daLAGSIRTLLEDADARRRFAEAGRQHLREAFDLQQN 386
Cdd:cd04946   361 --IVSSIMKFYLDGGDYKTMKISARECWEERFNAEVN 395
PRK15490 PRK15490
Vi polysaccharide biosynthesis glycosyltransferase TviE;
219-398 3.39e-12

Vi polysaccharide biosynthesis glycosyltransferase TviE;


Pssm-ID: 185387 [Multi-domain]  Cd Length: 578  Bit Score: 68.19  E-value: 3.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 219 AATELLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGAlnEAEVRAALDAAD 298
Cdd:PRK15490  397 ADTTIGGVFRFVGDKNPFAWIDFAARYLQHHPATRFVLVGDGDLRAEAQKRAEQLGILERILFVGA--SRDVGYWLQKMN 474

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 299 AFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIR---TLLEDADARRRFAEAGRQ 375
Cdd:PRK15490  475 VFILFSRYEGLPNVLIEAQMVGVPVISTPAGGSAECFIEGVSGFILDDAQTVNLDQACRyaeKLVNLWRSRTGICQQTQS 554

                         170       180
                  ....*....|....*....|...
gi 2018986280 376 HLREAFDLQQNVARLASLFVALP 398
Cdd:PRK15490  555 FLQERFTVEHMVGTFVKTIASQP 577
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 226-394 4.65e-12

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 67.75  E-value: 4.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 226 VGRLTAAKGQHVLLDACARLRAQGCAFRLTLVGQGSDEASLRERVRQLGLGEHVCFAGALNEaeVRAALDAADAFVLPSL 305
Cdd:PRK15179  523 VMRVDDNKRPFLWVEAAQRFAASHPKVRFIMVGGGPLLESVREFAQRLGMGERILFTGLSRR--VGYWLTQFNAFLLLSR 600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 306 AEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADA--LAGSIRTLLEDADARRRFAEAGRQHLREAFDL 383
Cdd:PRK15179  601 FEGLPNVLIEAQFSGVPVVTTLAGGAGEAVQEGVTGLTLPADTVTApdVAEALARIHDMCAADPGIARKAADWASARFSL 680

                         170
                  ....*....|.
gi 2018986280 384 QQNVARLASLF 394
Cdd:PRK15179  681 NQMIASTVRCY 691
PRK15484 PRK15484
lipopolysaccharide N-acetylglucosaminyltransferase;
219-375 2.24e-11

lipopolysaccharide N-acetylglucosaminyltransferase;


Pssm-ID: 185381 [Multi-domain]  Cd Length: 380  Bit Score: 64.81  E-value: 2.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 219 AATELLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVG-----QGSDEASLRERVRQLG--LGEHVCFAGALNEAEVR 291
Cdd:PRK15484  192 DETVLLYAGRISPDKGILLLMQAFEKLATAHSNLKLVVVGdptasSKGEKAAYQKKVLEAAkrIGDRCIMLGGQPPEKMH 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 292 AALDAADAFVLPS-LAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGL-LASPGDADALAGSIRTLLEDADaRRRF 369
Cdd:PRK15484  272 NYYPLADLVVVPSqVEEAFCMVAVEAMAAGKPVLASTKGGITEFVLEGITGYhLAEPMTSDSIISDINRTLADPE-LTQI 350


                  ....*.
gi 2018986280 370 AEAGRQ 375
Cdd:PRK15484  351 AEQAKD 356
GT4_mannosyltransferase-like cd03822
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ...
 223-378 2.47e-11

mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.


Pssm-ID: 340849 [Multi-domain]  Cd Length: 370  Bit Score: 64.71  E-value: 2.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAQGCAFRLTLVG-------QGSDEASLRERVRQLGLGEHVCFA-GALNEAEVRAAL 294
Cdd:cd03822   190 ILTFGFIGPGKGLEILLEALPELKAEFPDVRLVIAGelhpslaRYEGERYRKAAIEELGLQDHVDFHnNFLPEEEVPRYI 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 295 DAADAFVLP--SLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGkSGLLASPGDADALAGSIRTLLEDADARRRFAEA 372
Cdd:cd03822   270 SAADVVVLPylNTEQSSSGTLSYAIACGKPVISTPLRHAEELLADG-RGVLVPFDDPSAIAEAILRLLEDDERRQAIAER 348


                  ....*.
gi 2018986280 373 GRQHLR 378
Cdd:cd03822   349 AYAYAR 354
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
 223-372 2.63e-09

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 58.07  E-value: 2.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 223 LLCVGRLTAAKGQHVLLDACARLRAqgcafRLTLVGQGSDEASLReRVRQLGLGEHVCFAGALNEAEVRAALDAADAFVL 302
Cdd:cd03802   172 LAFLGRIAPEKGLEDAIRVARRAGL-----PLKIAGKVRDEDYFY-YLQEPLPGPRIEFIGEVGHDEKQELLGGARALLF 245

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2018986280 303 PSL-AEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGdaDALAGSIRTLLE-DADARRRFAEA 372
Cdd:cd03802   246 PINwDEPFGLVMIEAMACGTPVIAYRRGGLPEVIQHGETGFLVDSV--EEMAEAIANIDRiDRAACRRYAED 315
Glyco_trans_1_2 pfam13524
Glycosyl transferases group 1;
306-390 3.50e-09

Glycosyl transferases group 1;


Pssm-ID: 433281 [Multi-domain]  Cd Length: 93  Bit Score: 53.38  E-value: 3.50e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 306 AEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASpgDADALAGSIRTLLEDADARRRFAEAGRQHLREAFDLQQ 385
Cdd:pfam13524   9 PDSPNMRVFEAAACGAPLLTDRTPGLEELFEPGEEILLYR--DPEELAEKIRYLLEHPEERRAIAAAGRERVLAEHTYAH 86


                  ....*
gi 2018986280 386 NVARL 390
Cdd:pfam13524  87 RAEQL 91
PRK10307 PRK10307
colanic acid biosynthesis glycosyltransferase WcaI;
227-393 8.23e-09

colanic acid biosynthesis glycosyltransferase WcaI;


Pssm-ID: 236670 [Multi-domain]  Cd Length: 412  Bit Score: 56.91  E-value: 8.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 227 GRLTAAKGQHVLLDACARLRAQgCAFRLTLVGQGSDEASLRERVRQLGLGeHVCF-----AGALNE----AEV-----RA 292
Cdd:PRK10307  236 GNIGEKQGLELVIDAARRLRDR-PDLIFVICGQGGGKARLEKMAQCRGLP-NVHFlplqpYDRLPAllkmADChllpqKA 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 293 alDAADAfVLPS-----LAEGIPVVlmeAMAAgvpciscPVNGIPELIEdgKSGLLASPGDADALAGSIRTLLEDADARR 367
Cdd:PRK10307  314 --GAADL-VLPSkltnmLASGRNVV---ATAE-------PGTELGQLVE--GIGVCVEPESVEALVAAIAALARQALLRP 378

                         170       180       190
                  ....*....|....*....|....*....|
gi 2018986280 368 RFAEAGRQHLREAFD----LQQNVARLASL 393
Cdd:PRK10307  379 KLGTVAREYAERTLDkenvLRQFIADIRGL 408
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 267-373 2.32e-08

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 55.71  E-value: 2.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 267 RERVRQLGLGEHVCFAGALNEAEVraaLDAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIED--------G 338
Cdd:NF038011  357 RSLVASLGLQDKVKFLGFQKIDDL---LPQVGLMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQLIEGldeedralG 433

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2018986280 339 KSGLLASPGDADALAGSIRTLLEDADARRRFAEAG 373
Cdd:NF038011  434 AAGEVVAIADPQALARAALDLLRDPQRWQAAQAAG 468
GT4_ALG2-like cd03805
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ...
 308-385 3.51e-07

alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.


Pssm-ID: 340834 [Multi-domain]  Cd Length: 392  Bit Score: 51.82  E-value: 3.51e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2018986280 308 GIpvVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPgDADALAGSIRTLLEDADARRRFAEAGRQHLREAFDLQQ 385
Cdd:cd03805   313 GI--VPLEAMYAGKPVIACNSGGPLETVVEGVTGFLCEP-TPEAFAEAMLKLANDPDLADRMGAAGRKRVKEKFSREA 387
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
 224-343 3.63e-07

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 51.90  E-value: 3.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 224 LCVGRLTAAKGQHVLLDACARLraqgcAFRLTLVGQGSDEASLRERvrqlgLGEHVCFAGALNEAEVRAALDAADAFVLP 303
Cdd:cd03804   203 LTASRLVPYKRIDLAVEAFNEL-----PKRLVVIGDGPDLDRLRAM-----ASPNVEFLGYQPDEVLKELLSKARAFVFA 272

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2018986280 304 SlAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLL 343
Cdd:cd03804   273 A-EEDFGIVPVEAQACGTPVIAFGKGGALETVRPGPTGIL 311
GT5_Glycogen_synthase_DULL1-like cd03791
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ...
 225-361 3.63e-07

Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.


Pssm-ID: 340822 [Multi-domain]  Cd Length: 474  Bit Score: 52.18  E-value: 3.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 225 CVGRLTAAKGQHVLLDACARLRAQGCafRLTLVGQGSDE-----ASLRERVRqlglgEHVCFAGALNEAEVRAALDAADA 299
Cdd:cd03791   299 FVGRLTEQKGVDLILDALPELLEEGG--QLVVLGSGDPEyeqafRELAERYP-----GKVAVVIGFDEALAHRIYAGADF 371

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 300 FVLPSLAE--GIpvVLMEAMAAGVPCISCPVNGIPELIEDG------KSGLLASPGDADALAGSIRTLLE 361
Cdd:cd03791   372 FLMPSRFEpcGL--VQMYAMRYGTLPIVRRTGGLADTVFDYdpetgeGTGFVFEDYDAEALLAALRRALA 439
COG4641 COG4641
Spore maturation protein CgeB [Cell cycle control, cell division, chromosome partitioning];
252-380 1.84e-06

Spore maturation protein CgeB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443679 [Multi-domain]  Cd Length: 303  Bit Score: 49.16  E-value: 1.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 252 FRLTLVGQGSDEASLRERVRqlglgehvcFAGALNEAEVRAALDAADAFV----LPSLAEGIPVVLMEAMAAGVPCISCP 327
Cdd:COG4641   164 LRLKIYGPGWPKLALPANVR---------RGGHLPGEEHPAAYASSKITLnvnrMAASPDSPTRRTFEAAACGAFLLSDP 234

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2018986280 328 VNGIPELIEDGKSGLLASpgDADALAGSIRTLLEDADARRRFAEAGRQHLREA 380
Cdd:COG4641   235 WEGLEELFEPGEEVLVFR--DGEELAEKLRYLLADPEERRAIAEAGRRRVLAE 285
PLN00142 PLN00142
sucrose synthase
 295-381 2.40e-05

sucrose synthase


Pssm-ID: 215073 [Multi-domain]  Cd Length: 815  Bit Score: 46.51  E-value: 2.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 295 DAADAFVLPSLAEGIPVVLMEAMAAGVPCISCPVNGIPELIEDGKSGLLASPGDADALAGSIRTLLE----DADARRRFA 370
Cdd:PLN00142  665 DTKGAFVQPALYEAFGLTVVEAMTCGLPTFATCQGGPAEIIVDGVSGFHIDPYHGDEAANKIADFFEkckeDPSYWNKIS 744

                          90
                  ....*....|.
gi 2018986280 371 EAGRQHLREAF 381
Cdd:PLN00142  745 DAGLQRIYECY 755
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
113-190 1.67e-03

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 39.05  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018986280 113 VVRWMADRDLHHLHVHFATAGANVGLLARTIAPIGLSLTVHGPDEFDDVDGQHLRAK-----------VRAADLVVCISQ 181
Cdd:pfam13439  63 LRRLLRRERPDVVHAHSPFPLGLAALAARLRLGIPLVVTYHGLFPDYKRLGARLSPLrrllrrlerrlLRRADRVIAVSE 142


                  ....*....
gi 2018986280 182 FARSQLMRL 190
Cdd:pfam13439 143 AVADELRRL 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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