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Conserved domains on  [gi|2032366565|ref|WP_211272009|]
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sugar ABC transporter permease [Enterococcus canis]

Protein Classification

ABC transporter permease( domain architecture ID 10008345)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 1-282 1.44e-124

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 357.86  E-value: 1.44e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   1 MAIPGAVYMIIFSFIPIYGLVIAFKNYTVVDTIDSAQWVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIAV 80
Cdd:COG4209    32 MLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLISLLKLVFGFPLPIILAL 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  81 MIYELRDSVFKRTIQTISYLPHFLSWIILGGMIITWFS-SNGMINELLNFIGIQTQqNHMLDVGKYWWIASLSDVWKEAG 159
Cdd:COG4209   112 LLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSpDTGLVNQLLRALGGEPI-NFLTEPKYFRPIYVFSGIWKEAG 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 160 WGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFNSNLDQTLVLMNSQNQPKAEVINS 239
Cdd:COG4209   191 WGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVGFEQIYLLYNPLNYSTSDVIDT 270

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2032366565 240 YVYRVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKKLNDN 282
Cdd:COG4209   271 YVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLGEE 313
 
Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 1-282 1.44e-124

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 357.86  E-value: 1.44e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   1 MAIPGAVYMIIFSFIPIYGLVIAFKNYTVVDTIDSAQWVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIAV 80
Cdd:COG4209    32 MLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLISLLKLVFGFPLPIILAL 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  81 MIYELRDSVFKRTIQTISYLPHFLSWIILGGMIITWFS-SNGMINELLNFIGIQTQqNHMLDVGKYWWIASLSDVWKEAG 159
Cdd:COG4209   112 LLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSpDTGLVNQLLRALGGEPI-NFLTEPKYFRPIYVFSGIWKEAG 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 160 WGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFNSNLDQTLVLMNSQNQPKAEVINS 239
Cdd:COG4209   191 WGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVGFEQIYLLYNPLNYSTSDVIDT 270

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2032366565 240 YVYRVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKKLNDN 282
Cdd:COG4209   271 YVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLGEE 313
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
35-199 1.91e-14

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 71.78  E-value: 1.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  35 SAQWVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIAVMI-YELRdsvFKRTIQTISYLPHFLSWIILGGMI 113
Cdd:PRK10561   35 SSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAALVdYVVR---GSRFYQTLMLLPYAVAPAVAAVLW 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 114 ITWFSSN-GMINELLNFIGIQtqQNHMLDVGKYWWIASLSDVWKEAGWGTILYLATMAKIDPTYYEAAKMDGASRMRQIW 192
Cdd:PRK10561  112 IFLFNPGrGLITHFLAEFGYD--WNHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFF 189


                  ....*..
gi 2032366565 193 SITIPMI 199
Cdd:PRK10561  190 KLALPLI 196
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 6-284 5.15e-08

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 53.53  E-value: 5.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   6 AVYMIIFSFIPIYGLVIAfknyTVVDTidSAQWVGLDNFKIIMADKYFWQSVVNTLGISAL------KLAFGFVlpiiia 79
Cdd:TIGR03262  11 ILALLLFLLLPLLALLTK----SVYDS--DGDFIGLANFAEYFATPGLLQSLGNSLTVSAIvtaivvPLAFAFA------ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  80 vmiYELRDSV--FKRTIQTISYLPHFLSWIILGGMIITWFSSNGMINELLNFIGIqtqqnhmldVGKywWIASLSDVWKE 157
Cdd:TIGR03262  79 ---YALTRSRipGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSI---------YGF--WGIVIGEVFYT 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 158 AGWGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNiislnlilsvsGLFNSNLDQTLVLMNSQNQPKA--- 234
Cdd:TIGR03262 145 FPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKY-----------GLISAAFVVFTLVITDFGVPKVigg 213

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2032366565 235 --EVINSYVYRVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKKLNDNQS 284
Cdd:TIGR03262 214 dyNVLATDIYKQVIGQQNFPMGAVVGVLLLLPALLAFGIDRAIQRRQRAQLS 265
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-266 8.38e-07

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 48.43  E-value: 8.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  59 NTLGISALKLAFGFVLPIIIAVMIYELRdSVFKRTIQTISYLPHFLSWIILGGMIITWFSSNGMINELLNFIgiqtqqnh 138
Cdd:cd06261     3 NTLLLALIATLLALVLGLLLGIILARKR-GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLG-------- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 139 mldvgkyWWIASLSDVWKeAGWGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFNsn 218
Cdd:cd06261    74 -------LPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALG-- 143

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2032366565 219 lDQTLVLMNSQNQPKAEVINSYVYRVGLMQGDFSYATAVGLGISIISV 266
Cdd:cd06261   144 -EFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 71-280 4.76e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 43.06  E-value: 4.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  71 GFVLPIIIAVMIYELRDSVFKRTIQTISYLPHFLSWIILggmiitwfssngminellnfigiqTQQNHMLDVGKYWWIAS 150
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILL------------------------VVIAILSILGHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 151 LSDVWKEAGWGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFNsNLDQTLVLMNSQN 230
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALG-GAVLLEFLGSWPG 135

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2032366565 231 qpkaeviNSYVYRVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKKLN 280
Cdd:pfam00528 136 -------LGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLD 178
 
Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 1-282 1.44e-124

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 357.86  E-value: 1.44e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   1 MAIPGAVYMIIFSFIPIYGLVIAFKNYTVVDTIDSAQWVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIAV 80
Cdd:COG4209    32 MLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLISLLKLVFGFPLPIILAL 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  81 MIYELRDSVFKRTIQTISYLPHFLSWIILGGMIITWFS-SNGMINELLNFIGIQTQqNHMLDVGKYWWIASLSDVWKEAG 159
Cdd:COG4209   112 LLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSpDTGLVNQLLRALGGEPI-NFLTEPKYFRPIYVFSGIWKEAG 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 160 WGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFNSNLDQTLVLMNSQNQPKAEVINS 239
Cdd:COG4209   191 WGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVGFEQIYLLYNPLNYSTSDVIDT 270

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2032366565 240 YVYRVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKKLNDN 282
Cdd:COG4209   271 YVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLGEE 313
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
1-278 9.67e-51

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 168.77  E-value: 9.67e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   1 MAIPGAVYMIIFSFIPI-YGLVIAFKNYTVVDTidSAQWVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIA 79
Cdd:COG1175    23 FLLPALLLLLVFVLYPLlYTLYLSFTDWNLLGP--PPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQLVLGLLLA 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  80 VMIYelRDSVFKRTIQTISYLPHFLSWIIlGGMIITWF--SSNGMINELLNFIGIqTQQNHMLDVGKYWWIASLSDVWKE 157
Cdd:COG1175   101 LLLN--RKLRGRGFFRTLFFLPWVISPVV-VALIWKWLfnPDYGLLNALLGALGL-EPINWLGDPSLALPAVIIVTVWKG 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 158 AGWGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFNSnLDQTLVLMNSQNQPKAEVI 237
Cdd:COG1175   177 TGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQV-FDLVYVLTGGGPGNSTTTL 255

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 2032366565 238 NSYVYRVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKK 278
Cdd:COG1175   256 VLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
35-199 1.91e-14

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 71.78  E-value: 1.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  35 SAQWVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIAVMI-YELRdsvFKRTIQTISYLPHFLSWIILGGMI 113
Cdd:PRK10561   35 SSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAALVdYVVR---GSRFYQTLMLLPYAVAPAVAAVLW 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 114 ITWFSSN-GMINELLNFIGIQtqQNHMLDVGKYWWIASLSDVWKEAGWGTILYLATMAKIDPTYYEAAKMDGASRMRQIW 192
Cdd:PRK10561  112 IFLFNPGrGLITHFLAEFGYD--WNHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFF 189


                  ....*..
gi 2032366565 193 SITIPMI 199
Cdd:PRK10561  190 KLALPLI 196
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-200 7.00e-13

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 67.09  E-value: 7.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   1 MAIPGAVYMIIFSFIPI-YGLVIAFKNYTVVDTIDSAqwVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIA 79
Cdd:COG1176    14 LLLPALLWLLLFFVLPLlLLLVYSFTTRDPYGGVVPG--FTLENYARLFTDPLYLKVLLRTLWIALLTTLICLLLGYPIA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  80 VMIYeLRDSVFKRTIQTISYLPHFLSWIILGGMIITWFSSNGMINELLNFIGIQTQQNHMLdvgkYWWIAS-LSDVWKEA 158
Cdd:COG1176    92 YFLA-RAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEPLRLL----YTEFAVvIGLVYVYL 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2032366565 159 GWGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIR 200
Cdd:COG1176   167 PFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSL 208
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
6-278 7.95e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 65.18  E-value: 7.95e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   6 AVYMIIFSFIPIYGLVIafknytvvdtidSAQWVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIAVMIYeL 85
Cdd:COG1178    17 ALLLALLVLLPLLALLL------------RAFTDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLA-R 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  86 RDSVFKRTIQTISYLPHFLSWIILGGMIITWFSSNGMINELL-NFIGIQTqqnhmldvgkyWWIASLsdvwkeagWGTIL 164
Cdd:COG1178    84 TDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLrALFGLEP-----------PDIYGL--------GGIIL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 165 ----------YL---ATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIIslnlilsVSGLFnsnldqtLVLMNSQN- 230
Cdd:COG1178   145 vlvlfnypyvYLllrAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAI-------AAGAL-------LVFLLCLAd 210

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2032366565 231 -------QPKAEVINSYVYRVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKK 278
Cdd:COG1178   211 fgtplvlGGGYTTLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRR 265
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 6-280 3.14e-11

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 62.07  E-value: 3.14e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   6 AVYMIIFSFIPIYGLVIafknytvvdtidSAQWVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIAVMI--Y 83
Cdd:COG0555    17 LLYLSLIVLLPLAALVL------------KAAGLGWAEFWAVLTSPRVLAALKLSLGTALIAALINLVFGLPLAWVLvrY 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  84 ELRdsvFKRTIQTISYLPHFLSWIILGGMIITWFSSNGMINELLNFIGIQ---TQqnhmldvgkywwiaslsdvwkeagW 160
Cdd:COG0555    85 RFP---GKRLVDALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLGIKvafTP------------------------L 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 161 GTILYL-------------ATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVS---GLFNSnldqtlV 224
Cdd:COG0555   138 GIVLAQtfvslpfvvrtvqPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFAralGEFGA------V 211

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2032366565 225 LMNSQNQP-KAEVINSYVYrVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKKLN 280
Cdd:COG0555   212 IFIAGNLPmKTEILPLLIY-LKLEEGDYAGATAIALVLLLISFLLLLLINLLQRRSR 267
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
6-278 3.63e-08

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 54.01  E-value: 3.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   6 AVYMIIFSFIPIYGLVIAfknyTVVDTIDSAqwVGLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIAVMIyEL 85
Cdd:COG1178   295 LLLVLLGLLLPLLALLLW----SLTKALDDN--LTLDNYRFVLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLV-RR 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  86 RDSVFKRTIQTISYLPHFLSWIILG-GMIITWfssngmiNELLNFIGIQTqqnhmldvgkyWWIASLSdvwkeagwGTIL 164
Cdd:COG1178   368 RRGRLARLLDRLAMLPYAVPGIVLGlGLLLLF-------NRPLPLLLYGT-----------LAILVLA--------YVVR 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 165 YL--------ATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRN-IIS---LNLILSVsglfnSNLDQTLVLMNsqnqP 232
Cdd:COG1178   422 FLpfalrsleAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPgLLAaalLVFVTSM-----KELSATLLLRP----P 492

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 2032366565 233 KAEVINSYVYRVgLMQGDFSYATAVGLGISIISVVLLVLTNIVTKK 278
Cdd:COG1178   493 GFETLAVLIYQL-ASSGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 6-284 5.15e-08

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 53.53  E-value: 5.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   6 AVYMIIFSFIPIYGLVIAfknyTVVDTidSAQWVGLDNFKIIMADKYFWQSVVNTLGISAL------KLAFGFVlpiiia 79
Cdd:TIGR03262  11 ILALLLFLLLPLLALLTK----SVYDS--DGDFIGLANFAEYFATPGLLQSLGNSLTVSAIvtaivvPLAFAFA------ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  80 vmiYELRDSV--FKRTIQTISYLPHFLSWIILGGMIITWFSSNGMINELLNFIGIqtqqnhmldVGKywWIASLSDVWKE 157
Cdd:TIGR03262  79 ---YALTRSRipGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSI---------YGF--WGIVIGEVFYT 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 158 AGWGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNiislnlilsvsGLFNSNLDQTLVLMNSQNQPKA--- 234
Cdd:TIGR03262 145 FPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKY-----------GLISAAFVVFTLVITDFGVPKVigg 213

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2032366565 235 --EVINSYVYRVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKKLNDNQS 284
Cdd:TIGR03262 214 dyNVLATDIYKQVIGQQNFPMGAVVGVLLLLPALLAFGIDRAIQRRQRAQLS 265
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-266 8.38e-07

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 48.43  E-value: 8.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  59 NTLGISALKLAFGFVLPIIIAVMIYELRdSVFKRTIQTISYLPHFLSWIILGGMIITWFSSNGMINELLNFIgiqtqqnh 138
Cdd:cd06261     3 NTLLLALIATLLALVLGLLLGIILARKR-GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLG-------- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 139 mldvgkyWWIASLSDVWKeAGWGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFNsn 218
Cdd:cd06261    74 -------LPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALG-- 143

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2032366565 219 lDQTLVLMNSQNQPKAEVINSYVYRVGLMQGDFSYATAVGLGISIISV 266
Cdd:cd06261   144 -EFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 11-271 1.11e-06

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 48.94  E-value: 1.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  11 IFSFIPIYGLVI-AFKNYTVVDTIDSAQW---VGLDNFKIIMADKYFWQSVVNTLGISALklafGFVLPIIIAVMI-YEL 85
Cdd:COG0395    26 LLFLFPLYWMVVtSFKPPAEIFSGPPSLLpseFTLENYRAAFTDGPFGRYLLNSLIVAVV----STVLSLLLSSLAaYAL 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  86 --RDSVFKRtiqtisylphFLSWIILGGMIITWFSsnGMINELLNFIGIqtqqnHMLDvgKYW--WIASLSDVWkeaGWG 161
Cdd:COG0395   102 arFRFRGRK----------LLFLLILATLMIPGQV--LLIPLYLLFRQL-----GLLN--TYWglILPYLAFGL---PFG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 162 TILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFNSNLDQTLVLMNSQNQPKAEVINSYv 241
Cdd:COG0395   160 IFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASF- 238

                         250       260       270
                  ....*....|....*....|....*....|
gi 2032366565 242 yrVGLMQGDFSYATAVGLgISIISVVLLVL 271
Cdd:COG0395   239 --QGQYGTDWGLLMAAAV-IATLPVLILFL 265
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 7-200 6.55e-06

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 46.26  E-value: 6.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565   7 VYMIIFSFIPIYGLVIAFKNYTvvdtidsaqwvgLDNFKIIMADKYFWQSVVNTLGISALKLAFGFVLPIIIAVMIYeLR 86
Cdd:COG1177    25 LVLVLYSFNDSWFLTFPPEGFT------------LRWYAELFSDPRLLDALLNSLLIALLSTLLATVLGTPAALALA-RY 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  87 DSVFKRTIQTISYLPHFLSWIILGGMIITWFSSNGMINELLNFIGIQTqqnhmldvgkyWWIASlsdvwkeagWGTILYL 166
Cdd:COG1177    92 RFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHV-----------VFTLP---------FVVLVVL 151

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2032366565 167 ATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIR 200
Cdd:COG1177   152 ARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIA 185
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 71-280 4.76e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 43.06  E-value: 4.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565  71 GFVLPIIIAVMIYELRDSVFKRTIQTISYLPHFLSWIILggmiitwfssngminellnfigiqTQQNHMLDVGKYWWIAS 150
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILL------------------------VVIAILSILGHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2032366565 151 LSDVWKEAGWGTILYLATMAKIDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFNsNLDQTLVLMNSQN 230
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALG-GAVLLEFLGSWPG 135

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2032366565 231 qpkaeviNSYVYRVGLMQGDFSYATAVGLGISIISVVLLVLTNIVTKKLN 280
Cdd:pfam00528 136 -------LGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLD 178
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 172-216 1.06e-03

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 39.75  E-value: 1.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2032366565 172 IDPTYYEAAKMDGASRMRQIWSITIPMIRNIISLNLILSVSGLFN 216
Cdd:COG3833   169 IPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWN 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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