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Conserved domains on  [gi|2035453429|ref|WP_211581057|]
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iron ABC transporter permease [Gluconobacter wancherniae]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 16-324 7.21e-82

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 250.37  E-value: 7.21e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  16 ALCVGRYPLSLLQVLGVIGHSlhlvkAQDAAADAVVFQARLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLLGVLSG 95
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGP-----DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  96 AAFGAALAIVLG--LSAFVVQLGAFAGALLAVGVGLSVAGLLPEGGLLTLLLGGLISNALFTSLLSLVKYLADPlDQLPA 173
Cdd:COG0609    76 AALGAVLAIVLGggLSALGLPLAAFLGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLLADP-EQLRS 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 174 IVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVSMAGII 253
Cdd:COG0609   155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2035453429 254 GWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCARTLTS-GEIPLGIVTELFGALAFVLVLRRLR 324
Cdd:COG0609   235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILApAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 16-324 7.21e-82

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 250.37  E-value: 7.21e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  16 ALCVGRYPLSLLQVLGVIGHSlhlvkAQDAAADAVVFQARLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLLGVLSG 95
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGP-----DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  96 AAFGAALAIVLG--LSAFVVQLGAFAGALLAVGVGLSVAGLLPEGGLLTLLLGGLISNALFTSLLSLVKYLADPlDQLPA 173
Cdd:COG0609    76 AALGAVLAIVLGggLSALGLPLAAFLGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLLADP-EQLRS 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 174 IVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVSMAGII 253
Cdd:COG0609   155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2035453429 254 GWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCARTLTS-GEIPLGIVTELFGALAFVLVLRRLR 324
Cdd:COG0609   235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILApAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 11-322 9.88e-65

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 206.61  E-value: 9.88e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  11 AAFVLALCVGRYPLSLLQVLGVIGHSLhlvkaqDAAADAVVFQARLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLL 90
Cdd:pfam01032   4 LLILLSLFIGAVKISPSDVFSALLGGD------DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSIL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  91 GVLSGAAFGAALAIVLGLSA--FVVQLGAFAGALLAVGVGLSVAGLLPEGGLLTLLLGGLISNALFTSLLSLVKYLADPl 168
Cdd:pfam01032  78 GISSGAALGAVLAILLGGSLslFALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLLLNP- 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 169 DQLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVS 248
Cdd:pfam01032 157 EALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVA 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2035453429 249 MAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCARTLTSG-EIPLGIVTELFGALAFVLVLRR 322
Cdd:pfam01032 237 VVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPyELPVGIVTALIGAPFFIYLLLR 311
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 4-324 7.25e-48

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 163.59  E-value: 7.25e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429   4 LISICLCAAFVLALCVGRYPLSLLQVLGVIGHSLhlvkaqdaaadavVFQARLPRLVAAVLVGSALSCGGAVYQGVFRNP 83
Cdd:PRK03784   20 GLSVLLLLALLLSLCAGEQWISPGDWLSPRGELF-------------VWQLRLPRTLAVLLVGAALAVSGAVMQALFENP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  84 IVSPGLLGVLSGAAFGAALAIVLG---LSAFVVQLGAFAGALLAVGVGLSVAGLLPEG---GLLTLLLGGLISNALFTSL 157
Cdd:PRK03784   87 LAEPGLLGVSNGAGVALVAAVLLGqglLPPWALSLCAIAGALLITLILLRFARRHRLStsrLLLAGVALGIICSALMTWA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 158 LslvkYLADPLDqLPAIVNWLLGSLSDVSWQEIYWLAPLLIALtVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIV 237
Cdd:PRK03784  167 V----YFSTSLD-LRQLMYWMMGGFGGVDWRQSWLMLALLPVL-IWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 238 LATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCART-LTSGEIPLGIVTELFGALAF 316
Cdd:PRK03784  241 ATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARLaLASAELPIGVVTATLGAPVF 320


                  ....*...
gi 2035453429 317 VLVLRRLR 324
Cdd:PRK03784  321 IWLLLRSH 328
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-320 3.85e-39

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 138.84  E-value: 3.85e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  59 LVAAVLVGSALSCGGAVYQGVFRNPIVSPGLLGVLSGAAFGAALAIVLGLSAFVVQLGAFAGA-LLAVGVGLSVAGLLPE 137
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAgALAIALLVLLLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 138 GGLLTLLLGGLISNALFTSLLSLVKYLADplDQLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLG 217
Cdd:cd06550    81 LSPSKLILIGIVLSAFFSAGVILISLLSD--DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 218 DDEARSLGVPVSVLRPLLIVLATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCARTL 297
Cdd:cd06550   159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                         250       260
                  ....*....|....*....|...
gi 2035453429 298 TSGEIPLGIVTELFGALAFVLVL 320
Cdd:cd06550   239 LPSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 16-324 7.21e-82

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 250.37  E-value: 7.21e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  16 ALCVGRYPLSLLQVLGVIGHSlhlvkAQDAAADAVVFQARLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLLGVLSG 95
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGP-----DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  96 AAFGAALAIVLG--LSAFVVQLGAFAGALLAVGVGLSVAGLLPEGGLLTLLLGGLISNALFTSLLSLVKYLADPlDQLPA 173
Cdd:COG0609    76 AALGAVLAIVLGggLSALGLPLAAFLGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLLADP-EQLRS 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 174 IVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVSMAGII 253
Cdd:COG0609   155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2035453429 254 GWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCARTLTS-GEIPLGIVTELFGALAFVLVLRRLR 324
Cdd:COG0609   235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILApAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 11-322 9.88e-65

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 206.61  E-value: 9.88e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  11 AAFVLALCVGRYPLSLLQVLGVIGHSLhlvkaqDAAADAVVFQARLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLL 90
Cdd:pfam01032   4 LLILLSLFIGAVKISPSDVFSALLGGD------DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSIL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  91 GVLSGAAFGAALAIVLGLSA--FVVQLGAFAGALLAVGVGLSVAGLLPEGGLLTLLLGGLISNALFTSLLSLVKYLADPl 168
Cdd:pfam01032  78 GISSGAALGAVLAILLGGSLslFALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLLLNP- 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 169 DQLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVS 248
Cdd:pfam01032 157 EALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVA 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2035453429 249 MAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCARTLTSG-EIPLGIVTELFGALAFVLVLRR 322
Cdd:pfam01032 237 VVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPyELPVGIVTALIGAPFFIYLLLR 311
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 2-324 2.35e-52

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 175.43  E-value: 2.35e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429   2 FPLISICLCAAFVLALCVGRYPLSLLQVLGVIGHSLhlvkaqdaaadavVFQARLPRLVAAVLVGSALSCGGAVYQGVFR 81
Cdd:COG4139    15 LLLLLLLLLLLFVLSLCAGEVWIPPTQWLSEAWQLF-------------VWQLRLPRTLAAVLVGASLAVSGAVMQALFE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  82 NPIVSPGLLGVLSGAAFGAALAIVLGLSAF---VVQLGAFAGALLAVG--VGLSVAGLLPEGGLLTLLLGGLISNALFTS 156
Cdd:COG4139    82 NPLAEPGLLGISNGAGVGLVLVVLLGGGLLppwLLSLAAIAGALLVTLllLAFARRRLSNARLLLIGVALGIICSAIMTW 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 157 LLslvkYLADPLDqLPAIVNWLLGSLSDVSWQEIYWLAPLLIALtVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLI 236
Cdd:COG4139   162 AV----YFSSSLD-LRQLMYWMMGSFGGVDWRQLWLLLALLPVL-LWLCLQGKPLNLLLLGENQARQLGLSVHRWRNLLV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 237 VLATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCART-LTSGEIPLGIVTELFGALA 315
Cdd:COG4139   236 LATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLADIIARLaLSSAELPIGVVTATLGAPV 315


                  ....*....
gi 2035453429 316 FVLVLRRLR 324
Cdd:COG4139   316 FIWLLLRRR 324
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 4-324 7.25e-48

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 163.59  E-value: 7.25e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429   4 LISICLCAAFVLALCVGRYPLSLLQVLGVIGHSLhlvkaqdaaadavVFQARLPRLVAAVLVGSALSCGGAVYQGVFRNP 83
Cdd:PRK03784   20 GLSVLLLLALLLSLCAGEQWISPGDWLSPRGELF-------------VWQLRLPRTLAVLLVGAALAVSGAVMQALFENP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  84 IVSPGLLGVLSGAAFGAALAIVLG---LSAFVVQLGAFAGALLAVGVGLSVAGLLPEG---GLLTLLLGGLISNALFTSL 157
Cdd:PRK03784   87 LAEPGLLGVSNGAGVALVAAVLLGqglLPPWALSLCAIAGALLITLILLRFARRHRLStsrLLLAGVALGIICSALMTWA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 158 LslvkYLADPLDqLPAIVNWLLGSLSDVSWQEIYWLAPLLIALtVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIV 237
Cdd:PRK03784  167 V----YFSTSLD-LRQLMYWMMGGFGGVDWRQSWLMLALLPVL-IWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 238 LATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCART-LTSGEIPLGIVTELFGALAF 316
Cdd:PRK03784  241 ATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARLaLASAELPIGVVTATLGAPVF 320


                  ....*...
gi 2035453429 317 VLVLRRLR 324
Cdd:PRK03784  321 IWLLLRSH 328
btuC PRK09535
cobalamin ABC transporter permease BtuC;
53-322 2.37e-43

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 152.98  E-value: 2.37e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  53 QARLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLLGVLSGAAFGAALAIVLGLS-AFVVQLGAFAGALLAVGVGLSV 131
Cdd:PRK09535   93 QIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAvPFGLQAAAFAGALVAAFGVYAI 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 132 AGLLPEGGLLTLLLGGLISNALFTSLLSLVkyLADPLDQLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVL 211
Cdd:PRK09535  173 ATENGRTPVATLLLAGVAVQTFLGAVISYL--LLHSGESLRRAVYWLMGHLHGSTWSDVEVALPVVVVGFVVLLAYARDL 250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 212 DVLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLAD 291
Cdd:PRK09535  251 NVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPTSALAGASFLVATD 330

                         250       260       270
                  ....*....|....*....|....*....|.
gi 2035453429 292 MCARTlTSGEIPLGIVTELFGALAFVLVLRR 322
Cdd:PRK09535  331 TVARS-GPAEVPVGIVTAALGAPFFLYLLRT 360
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 11-322 1.15e-42

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 150.27  E-value: 1.15e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  11 AAFVLALCVGRYPLSLLQVLGVighslhLVKAQDAAADAVVFQARLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLL 90
Cdd:COG4779    35 ALAVLALTLGDYPLSPGDVLRA------LLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSLTRNPLASPDII 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  91 GVLSGAAFGAALAIVL-GLSAFVVQLGAFAGALLAVGVGLSVAGLLPEGGLLTLLLGGLISnALFTSLLSLVKYLADpLD 169
Cdd:COG4779   109 GITAGASAGAVAAIVVlGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVS-AMLTAVNSYLLTRAD-LE 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 170 QLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVSM 249
Cdd:COG4779   187 DAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAVALAAVATAA 266

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2035453429 250 AGIIGWVGLLVPHIARLMVGAeHRHMMPVCALLGATGLVLADMCARTLTSG-EIPLGIVTELFGALAFVLVLRR 322
Cdd:COG4779   267 AGPIAFVALAAPQIARRLTRS-PGPPLLPSALVGALLLLAADLVAQHLLAPvQLPVGVVTGALGGPYLLWLLIR 339
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
55-324 3.84e-41

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 151.92  E-value: 3.84e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  55 RLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLLGVLSGAAFGAALAIVL--GLSAFVVQLGAFAGALLAVGVGLSVA 132
Cdd:PRK10577  397 RLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLvpGAGFGWLLAAALLGALAALALILLLA 476

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 133 GLLPEGGLLTLLLGGLISnALFTSLLSLVKYLADPldQLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLD 212
Cdd:PRK10577  477 RRGGFAPERLLLTGIALS-ALFTALIQLLLASGDP--RAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLD 553

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 213 VLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADM 292
Cdd:PRK10577  554 LLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADW 633

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2035453429 293 CARTLTSG-EIPLGIVTELFGALAFVLVLRRLR 324
Cdd:PRK10577  634 LGRTLLFPyQIPAGLLAALIGAPYFLWLLRRSR 666
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-324 3.54e-39

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 146.14  E-value: 3.54e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429   1 MFPLISICLCAAFVLALCVGRYPLSLLQVLGVIGHSlhlvkAQDAAADAVVFQARLPRLVAAVLVGSALSCGGAVYQGVF 80
Cdd:PRK10577   13 PALLLALLLLLALALTLTQLSAALPLSQWLQALWGP-----DADDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQQVL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  81 RNPIVSPGLLGVLSGAAFGAALAIVL--GLSAFVVQLGAFAGALLAVGVGLSVAGLLPEGGLLTLLLGGLIsNALFTSLL 158
Cdd:PRK10577   88 RNPLASPTTLGVAAGAQLALVLATLFapALLALASQLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVV-SLYLGALT 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 159 SLVKYLADplDQLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIVL 238
Cdd:PRK10577  167 TLLLLFNE--QYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALAL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 239 ATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCARTLTSG---EIPLGIVTELFGALA 315
Cdd:PRK10577  245 AVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGVggeLLPTGAVTALIGAPL 324


                  ....*....
gi 2035453429 316 FVLVLRRLR 324
Cdd:PRK10577  325 LLWLLPRLR 333
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-320 3.85e-39

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 138.84  E-value: 3.85e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  59 LVAAVLVGSALSCGGAVYQGVFRNPIVSPGLLGVLSGAAFGAALAIVLGLSAFVVQLGAFAGA-LLAVGVGLSVAGLLPE 137
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAgALAIALLVLLLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 138 GGLLTLLLGGLISNALFTSLLSLVKYLADplDQLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLG 217
Cdd:cd06550    81 LSPSKLILIGIVLSAFFSAGVILISLLSD--DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 218 DDEARSLGVPVSVLRPLLIVLATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCARTL 297
Cdd:cd06550   159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                         250       260
                  ....*....|....*....|...
gi 2035453429 298 TSGEIPLGIVTELFGALAFVLVL 320
Cdd:cd06550   239 LPSELPVGPVTALLGAPYFLYLL 261
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
53-322 2.53e-36

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 133.28  E-value: 2.53e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  53 QARLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLLGVLSGAAFGAALAIVLG---LSAFVVQLGAFAGALLAVGVGL 129
Cdd:PRK11228   49 NLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSALSptpFAGYSLAFIAACGGGLSWLLVM 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 130 SVAGLLPEGGLLTLLLGGLIS-NALFTSLLSLVKYLADplDQLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAA 208
Cdd:PRK11228  129 TAGGGWRHTHDRNRLILAGIAlSALCMALTRITLLLAE--DHAYGIFYWLAGGVSHARWQEVWQLLPFVVTAVPVVLLLA 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 209 PVLDVLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLV 288
Cdd:PRK11228  207 NQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPMSMLLGATLML 286

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2035453429 289 LADMCARTLT-SGEIPLGIVTELFGALAFVLVLRR 322
Cdd:PRK11228  287 LADLLARALAfPGELPAGAVLALIGAPCFVWLARR 321
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
2-324 3.67e-33

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 124.77  E-value: 3.67e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429   2 FPLISICLCAAFVLALCVGRYPLSLLQVLGV--IGHSLHLVkaqdaaadavVFQARLPRLVAAVLVGSALSCGGAVYQGV 79
Cdd:PRK09777    6 VIFITLALAGCALLSLRMGVIPLPWRALLTDwqAGDEHYYV----------LMEYRLPRLLLALFVGAALAVSGVLVQGI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  80 FRNPIVSPGLLGVLSGAAFGAALAIVL--GLSAFVVQLGAFAGALLAVGVGLSVAGLLPEGGLLTLLLGGLISNALFTSL 157
Cdd:PRK09777   76 VRNPLASPDILGVNHAASLASVGALLLfpSLPVMWLPLLAFIGGMAGLILLKMLAGTHQPMKLALTGVALSALWASLTDY 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 158 LSLVKyladPLDQLPAIVnWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIV 237
Cdd:PRK09777  156 LMLSR----PQDINNALL-WLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALL 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 238 LATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLVLADMCARTLTSG-EIPLGIVTELFGALAF 316
Cdd:PRK09777  231 LAVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPlELPAGVLTAIIGAPWF 310


                  ....*...
gi 2035453429 317 VLVLRRLR 324
Cdd:PRK09777  311 FWLLVRMR 318
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
53-326 1.75e-26

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 107.10  E-value: 1.75e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  53 QARLPRLVAAVLVGSALSCGGAVYQGVFRNPIVSPGLLGVLSGAAFGAALAIVL-GLSAFVVQLG-AFAGALLAVGVGLS 130
Cdd:PRK10441   58 DARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALfGYSSAQEQLAmAFAGALVASLIVAF 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 131 VAGLLPEGGLLTLLLGGLISNALFTSLLSLVKYLADPL--DQLPAivnWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAA 208
Cdd:PRK10441  138 TGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDvyDQLRF---WQAGSLDIRNLHTLKVVLIPVLIAGATALLLS 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 209 PVLDVLSLGDDEARSLGVPVSVLRPLLIVLATFACALTVSMAGIIGWVGLLVPHIARLMVGAEHRHMMPVCALLGATGLV 288
Cdd:PRK10441  215 RALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLL 294

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 2035453429 289 LADMCARTLTSGEIPLGIVTELFGALAFVLVLRRLRGG 326
Cdd:PRK10441  295 FADIIGRLLVPGELRVSVVSAFIGAPVLIFLVRRKTRG 332
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
4-322 4.70e-21

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 91.70  E-value: 4.70e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429   4 LISICLCAAfVLALCVGRYPLSLLQVLGVighslhLVKAQDAAADAVVFQARLPRLVAAVLVGSALSCGGAVYQGVFRNP 83
Cdd:PRK10440   15 LLAACVAAG-LWGLRSGAVTLETSQVFAA------LMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429  84 IVSPGLLGVLSGAAFGAALAIVL-GLSAFVVQLGAFAGALLAVGVGLSVAGLLPEGGLLTLLLGGLIS---NALFTSLLs 159
Cdd:PRK10440   88 LGSPDVMGFNTGAWSGVLVAMVLfGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRamlVAFNTWLL- 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 160 lvkyLADPLDQLPAIVNWLLGSLSDVSWQEIYWLAPLLIALTVLLIRAAPVLDVLSLGDDEARSLGVPVSVLRPLLIVLA 239
Cdd:PRK10440  167 ----LKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLVA 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035453429 240 TFACALTVSMAGIIGWVGLLVPHIARLMVGAEhRHMMPVCALLGATGLVLADMCARTL-TSGEIPLGIVTELFGALAFVL 318
Cdd:PRK10440  243 VVLTAAATALAGPISFIALVAPHIARRLSGTA-RWGLTQAALCGALLLLAADLCAQQLfMPYQLPVGVVTVSLGGIYLIV 321


                  ....
gi 2035453429 319 VLRR 322
Cdd:PRK10440  322 LLIQ 325
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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