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Conserved domains on  [gi|2045320645|ref|WP_213844964|]
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IS1 family transposase, partial [Escherichia coli]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DDE_Tnp_IS1 super family cl44371
IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This ...
 18-74 2.57e-35

IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This family represents bacterial IS1 transposases.


The actual alignment was detected with superfamily member pfam03400:

Pssm-ID: 281403  Cd Length: 131  Bit Score: 115.84  E-value: 2.57e-35
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2045320645  18 VIVCAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPF 74
Cdd:pfam03400   1 AIICAELDEQWGFVGAKARQHWLFYAYDRKRGGVLAHTFGERTDATCGELLALLSPF 57
 
Name Accession Description Interval E-value
DDE_Tnp_IS1 pfam03400
IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This ...
 18-74 2.57e-35

IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This family represents bacterial IS1 transposases.


Pssm-ID: 281403  Cd Length: 131  Bit Score: 115.84  E-value: 2.57e-35
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2045320645  18 VIVCAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPF 74
Cdd:pfam03400   1 AIICAELDEQWGFVGAKARQHWLFYAYDRKRGGVLAHTFGERTDATCGELLALLSPF 57
transpos_IS1 NF033558
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
 1-74 7.77e-30

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 103.89  E-value: 7.77e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2045320645   1 KKLRPQSVTSRIQPGSDVIVCAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPF 74
Cdd:NF033558   77 KKLGPRQVTPEPLKPADIVLICELDELWTFVGNKKNKRWLWYAYDRKTKRILAYVFGDRSAETFRKLWALLKPF 150
InsB COG1662
Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];
1-74 3.20e-21

Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];


Pssm-ID: 441268 [Multi-domain]  Cd Length: 193  Bit Score: 81.67  E-value: 3.20e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2045320645   1 KKLRPQSVTSRIQPGSDVIVCAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPF 74
Cdd:COG1662    43 NTKLVAVYVQLKVPNLSDKRLVEVDELWTFVGSKKNKVWIWYAVDRDTGRIVAFVVGDRDKKTARKLWEKLKPF 116
 
Name Accession Description Interval E-value
DDE_Tnp_IS1 pfam03400
IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This ...
 18-74 2.57e-35

IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This family represents bacterial IS1 transposases.


Pssm-ID: 281403  Cd Length: 131  Bit Score: 115.84  E-value: 2.57e-35
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2045320645  18 VIVCAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPF 74
Cdd:pfam03400   1 AIICAELDEQWGFVGAKARQHWLFYAYDRKRGGVLAHTFGERTDATCGELLALLSPF 57
transpos_IS1 NF033558
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
 1-74 7.77e-30

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 103.89  E-value: 7.77e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2045320645   1 KKLRPQSVTSRIQPGSDVIVCAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPF 74
Cdd:NF033558   77 KKLGPRQVTPEPLKPADIVLICELDELWTFVGNKKNKRWLWYAYDRKTKRILAYVFGDRSAETFRKLWALLKPF 150
InsB COG1662
Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];
1-74 3.20e-21

Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];


Pssm-ID: 441268 [Multi-domain]  Cd Length: 193  Bit Score: 81.67  E-value: 3.20e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2045320645   1 KKLRPQSVTSRIQPGSDVIVCAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPF 74
Cdd:COG1662    43 NTKLVAVYVQLKVPNLSDKRLVEVDELWTFVGSKKNKVWIWYAVDRDTGRIVAFVVGDRDKKTARKLWEKLKPF 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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