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Conserved domains on  [gi|2074466784|ref|WP_219523109|]
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aspartate aminotransferase family protein [Nosocomiicoccus ampullae]

Protein Classification

pyridoxal phosphate-dependent decarboxylase family protein( domain architecture ID 10000562)

pyridoxal phosphate-dependent decarboxylase family protein is primarily involved in the biosynthesis of amino acids and amino acid-derived metabolites, but it is also found in the biosynthetic pathways of amino sugars and in the synthesis or catabolism of neurotransmitters

CATH:  3.40.640.10
EC:  4.1.1.-
Gene Ontology:  GO:0016830|GO:0030170|GO:0019752
PubMed:  8690703|7748903
SCOP:  4003328

Graphical summary

 Zoom to residue level

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Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GadA COG0076
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ...
 14-464 1.86e-142

Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


:

Pssm-ID: 439846 [Multi-domain]  Cd Length: 460  Bit Score: 416.16  E-value: 1.86e-142
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  14 IRDEVNKYLNQDvsRLNATEQAPKELTQKYeKMPVPKTGRDIYEVLSELNNEVLTYLYRPNHKRAFSFIPGPASRLSWLG 93
Cdd:COG0076     9 ALDLAADYLAGL--DRPVFGPSPEELRAAL-DEPLPEEGLPPEEALAELEDLVLPGSVDWNHPRFLAFVTGGTTPAALAA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  94 DILTTANNIHASNFKNATLPISIERNLINYLADKIGYEvKPSGGVFVSGGSMANLTAVVTARDRK----VTLDKLTKT-- 167
Cdd:COG0076    86 DLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLP-EGAGGVFTSGGTEANLLALLAARDRAlarrVRAEGLPGApr 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 168 -TVYLTSQTHHSGRKALHVAGFPTENIRIIDHNEDFTMNVSHLKETVEKDVKNGYIPALVISTAGTTNTGAVDDFNKIAD 246
Cdd:COG0076   165 pRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPLAEIAD 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 247 ICEAYNIWQHVDGAYGASHLLSTKGKSLFKGIERSDSVTWDAHKLLFQTYSCAMIIVKDKNNLINSYGEKAEYLDdiTSD 326
Cdd:COG0076   245 IAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREAFSFHASYLG--PAD 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 327 DDVIDPEMLGIELTRPARAVKLWLTLQVIGEDEFRKRIDYGQELAEYTKEYVESLENFEIISQPSLSILSFRYYNDSYTD 406
Cdd:COG0076   323 DGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELLAPPELNIVCFRYKPAGLDE 402

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2074466784 407 EenDYLNNLAAKKLADSGYGVAYTTTLNNKKVFRMCTINPETTESDVKETIDRLNRYI 464
Cdd:COG0076   403 E--DALNYALRDRLRARGRAFLSPTKLDGRVVLRLVVLNPRTTEDDVDALLDDLREAA 458
 
Name Accession Description Interval E-value
GadA COG0076
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ...
 14-464 1.86e-142

Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 439846 [Multi-domain]  Cd Length: 460  Bit Score: 416.16  E-value: 1.86e-142
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  14 IRDEVNKYLNQDvsRLNATEQAPKELTQKYeKMPVPKTGRDIYEVLSELNNEVLTYLYRPNHKRAFSFIPGPASRLSWLG 93
Cdd:COG0076     9 ALDLAADYLAGL--DRPVFGPSPEELRAAL-DEPLPEEGLPPEEALAELEDLVLPGSVDWNHPRFLAFVTGGTTPAALAA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  94 DILTTANNIHASNFKNATLPISIERNLINYLADKIGYEvKPSGGVFVSGGSMANLTAVVTARDRK----VTLDKLTKT-- 167
Cdd:COG0076    86 DLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLP-EGAGGVFTSGGTEANLLALLAARDRAlarrVRAEGLPGApr 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 168 -TVYLTSQTHHSGRKALHVAGFPTENIRIIDHNEDFTMNVSHLKETVEKDVKNGYIPALVISTAGTTNTGAVDDFNKIAD 246
Cdd:COG0076   165 pRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPLAEIAD 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 247 ICEAYNIWQHVDGAYGASHLLSTKGKSLFKGIERSDSVTWDAHKLLFQTYSCAMIIVKDKNNLINSYGEKAEYLDdiTSD 326
Cdd:COG0076   245 IAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREAFSFHASYLG--PAD 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 327 DDVIDPEMLGIELTRPARAVKLWLTLQVIGEDEFRKRIDYGQELAEYTKEYVESLENFEIISQPSLSILSFRYYNDSYTD 406
Cdd:COG0076   323 DGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELLAPPELNIVCFRYKPAGLDE 402

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2074466784 407 EenDYLNNLAAKKLADSGYGVAYTTTLNNKKVFRMCTINPETTESDVKETIDRLNRYI 464
Cdd:COG0076   403 E--DALNYALRDRLRARGRAFLSPTKLDGRVVLRLVVLNPRTTEDDVDALLDDLREAA 458
DOPA_deC_like cd06450
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 79-463 2.55e-104

DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.


Pssm-ID: 99743 [Multi-domain]  Cd Length: 345  Bit Score: 314.53  E-value: 2.55e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  79 FSFIPGPASRLSWLGDILTTANNIHASNFKNATLPISIERNLINYLADKIGYEVKPSGGVFVSGGSMANLTAVVTARDRK 158
Cdd:cd06450     2 LAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLPSEDADGVFTSGGSESNLLALLAARDRA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 159 V------TLDKLTKTTVYLTSQTHHSGRKALHVAGfptENIRIIDHNEDFTMNVSHLKETVEKDVKNGYIPALVISTAGT 232
Cdd:cd06450    82 RkrlkagGGRGIDKLVIVCSDQAHVSVEKAAAYLD---VKVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVATAGT 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 233 TNTGAVDDFNKIADICEAYNIWQHVDGAYGASHLLSTKGKSLFKGIERSDSVTWDAHKLLFQTYSCAMIIVkdknnlins 312
Cdd:cd06450   159 TDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLV--------- 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 313 ygekaeyldditsdddvidpemlgieltrpaRAVKLWLTLQVIGEDEFRKRIDYGQELAEYTKEYVESLENFEIISQPSL 392
Cdd:cd06450   230 -------------------------------RALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGFELLGEPNL 278

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2074466784 393 SILSFRYYNDSYTDEENDYLnnlaAKKLADSGYGVAYTTTLNNKKVFRMCTINPETTESDVKETIDRLNRY 463
Cdd:cd06450   279 SLVCFRLKPSVKLDELNYDL----SDRLNERGGWHVPATTLGGPNVLRFVVTNPLTTRDDADALLEDIERA 345
Pyridoxal_deC pfam00282
Pyridoxal-dependent decarboxylase conserved domain;
75-399 2.56e-58

Pyridoxal-dependent decarboxylase conserved domain;


Pssm-ID: 395219  Cd Length: 373  Bit Score: 196.48  E-value: 2.56e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  75 HKRAFSFIPGPASRLSWLGDILTTANNIHASNFKNATLPISIERNLINYLADKIG----YEVKPSGGVFVSGGSMANLTA 150
Cdd:pfam00282  39 SPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTELENVVMNWLGEMLGlpaeFLGQEGGGVLQPGSSESNLLA 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 151 VVTARDRK-----------VTLDKLTKTTVYLTSQTHHSGRKALHVAGFpteNIRIIDHNEDFTMNVSHLKETVEKDVKN 219
Cdd:pfam00282 119 LLAARTKWikrmkaagkpaDSSGILAKLVAYTSDQAHSSIEKAALYGGV---KLREIPSDDNGKMRGMDLEKAIEEDKEN 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 220 GYIPALVISTAGTTNTGAVDDFNKIADICEAYNIWQHVDGAYGASHLLSTKGKSLFKGIERSDSVTWDAHKLLFQTYSCA 299
Cdd:pfam00282 196 GLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAYGGSAFICPEFRHWLFGIERADSITFNPHKWMLVLLDCS 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 300 MIIVKDKNNLINSYGEKAEYLDDITSDDDVIDpemLGIELTRPARAVKLWLTLQVIGEDEFRKRIDYGQELAEYTKEYVE 379
Cdd:pfam00282 276 AVWVKDKEALQQAFQFNPLYLGHTDSAYDTGH---KQIPLSRRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIR 352

                         330       340
                  ....*....|....*....|
gi 2074466784 380 SLENFEIISQPSLSILSFRY 399
Cdd:pfam00282 353 KDGRFEICAEVGLGLVCFRL 372
PLN02880 PLN02880
tyrosine decarboxylase
 49-455 2.05e-49

tyrosine decarboxylase


Pssm-ID: 215475 [Multi-domain]  Cd Length: 490  Bit Score: 175.87  E-value: 2.05e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  49 PKTGRDIYEVLSELNNEVL---TYLYRPNHkraFSFIPGPASRLSWLGDILTTANNIhaSNFKNATLPISIERNLInyLA 125
Cdd:PLN02880   56 PNQPETLDQVLDDVQAKILpgvTHWQSPNY---FAYYPSNSSVAGFLGEMLSAGLNI--VGFSWITSPAATELEMI--VL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 126 DKIGYEVK-PS--------GGVFVSGGSMANLTAVVTARD---RKVTLDKLTKTTVYLTSQTHHSGRKALHVAGFPTENI 193
Cdd:PLN02880  129 DWLAKLLNlPEqflstgngGGVIQGTASEAVLVVLLAARDrvlRKVGKNALEKLVVYASDQTHSALQKACQIAGIHPENC 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 194 RII--DHNEDFTMNVSHLKETVEKDVKNGYIPALVISTAGTTNTGAVDDFNKIADICEAYNIWQHVDGAYGASHLLSTKG 271
Cdd:PLN02880  209 RLLktDSSTNYALAPELLSEAISTDLSSGLIPFFLCATVGTTSSTAVDPLLELGKIAKSNGMWFHVDAAYAGSACICPEY 288

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 272 KSLFKGIERSDSVTWDAHKLLFQTYSCAMIIVKDKNNLINSYGEKAEYLDDITSD-DDVIDPEMLGIELTRPARAVKLWL 350
Cdd:PLN02880  289 RHYIDGVEEADSFNMNAHKWFLTNFDCSLLWVKDRNALIQSLSTNPEFLKNKASQaNSVVDYKDWQIPLGRRFRSLKLWM 368

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 351 TLQVIGEDEFRKRIDYGQELAEYTKEYVESLENFEIISQPSLSILSFRYYNDSYTDEENDYLNNLAAKKLADSGYGVAYT 430
Cdd:PLN02880  369 VLRLYGVENLQSYIRNHIKLAKEFEQLVAQDSRFEVVTPRIFSLVCFRLVPPKNNEDNGNKLNHDLLDAVNSSGKIFISH 448

                         410       420
                  ....*....|....*....|....*
gi 2074466784 431 TTLNNKKVFRMCTINPETTESDVKE 455
Cdd:PLN02880  449 TVLSGKYVLRFAVGAPLTEERHVTA 473
 
Name Accession Description Interval E-value
GadA COG0076
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ...
 14-464 1.86e-142

Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 439846 [Multi-domain]  Cd Length: 460  Bit Score: 416.16  E-value: 1.86e-142
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  14 IRDEVNKYLNQDvsRLNATEQAPKELTQKYeKMPVPKTGRDIYEVLSELNNEVLTYLYRPNHKRAFSFIPGPASRLSWLG 93
Cdd:COG0076     9 ALDLAADYLAGL--DRPVFGPSPEELRAAL-DEPLPEEGLPPEEALAELEDLVLPGSVDWNHPRFLAFVTGGTTPAALAA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  94 DILTTANNIHASNFKNATLPISIERNLINYLADKIGYEvKPSGGVFVSGGSMANLTAVVTARDRK----VTLDKLTKT-- 167
Cdd:COG0076    86 DLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLP-EGAGGVFTSGGTEANLLALLAARDRAlarrVRAEGLPGApr 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 168 -TVYLTSQTHHSGRKALHVAGFPTENIRIIDHNEDFTMNVSHLKETVEKDVKNGYIPALVISTAGTTNTGAVDDFNKIAD 246
Cdd:COG0076   165 pRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPLAEIAD 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 247 ICEAYNIWQHVDGAYGASHLLSTKGKSLFKGIERSDSVTWDAHKLLFQTYSCAMIIVKDKNNLINSYGEKAEYLDdiTSD 326
Cdd:COG0076   245 IAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREAFSFHASYLG--PAD 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 327 DDVIDPEMLGIELTRPARAVKLWLTLQVIGEDEFRKRIDYGQELAEYTKEYVESLENFEIISQPSLSILSFRYYNDSYTD 406
Cdd:COG0076   323 DGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELLAPPELNIVCFRYKPAGLDE 402

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2074466784 407 EenDYLNNLAAKKLADSGYGVAYTTTLNNKKVFRMCTINPETTESDVKETIDRLNRYI 464
Cdd:COG0076   403 E--DALNYALRDRLRARGRAFLSPTKLDGRVVLRLVVLNPRTTEDDVDALLDDLREAA 458
DOPA_deC_like cd06450
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 79-463 2.55e-104

DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.


Pssm-ID: 99743 [Multi-domain]  Cd Length: 345  Bit Score: 314.53  E-value: 2.55e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  79 FSFIPGPASRLSWLGDILTTANNIHASNFKNATLPISIERNLINYLADKIGYEVKPSGGVFVSGGSMANLTAVVTARDRK 158
Cdd:cd06450     2 LAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLPSEDADGVFTSGGSESNLLALLAARDRA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 159 V------TLDKLTKTTVYLTSQTHHSGRKALHVAGfptENIRIIDHNEDFTMNVSHLKETVEKDVKNGYIPALVISTAGT 232
Cdd:cd06450    82 RkrlkagGGRGIDKLVIVCSDQAHVSVEKAAAYLD---VKVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVATAGT 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 233 TNTGAVDDFNKIADICEAYNIWQHVDGAYGASHLLSTKGKSLFKGIERSDSVTWDAHKLLFQTYSCAMIIVkdknnlins 312
Cdd:cd06450   159 TDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLV--------- 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 313 ygekaeyldditsdddvidpemlgieltrpaRAVKLWLTLQVIGEDEFRKRIDYGQELAEYTKEYVESLENFEIISQPSL 392
Cdd:cd06450   230 -------------------------------RALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGFELLGEPNL 278

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2074466784 393 SILSFRYYNDSYTDEENDYLnnlaAKKLADSGYGVAYTTTLNNKKVFRMCTINPETTESDVKETIDRLNRY 463
Cdd:cd06450   279 SLVCFRLKPSVKLDELNYDL----SDRLNERGGWHVPATTLGGPNVLRFVVTNPLTTRDDADALLEDIERA 345
Pyridoxal_deC pfam00282
Pyridoxal-dependent decarboxylase conserved domain;
75-399 2.56e-58

Pyridoxal-dependent decarboxylase conserved domain;


Pssm-ID: 395219  Cd Length: 373  Bit Score: 196.48  E-value: 2.56e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  75 HKRAFSFIPGPASRLSWLGDILTTANNIHASNFKNATLPISIERNLINYLADKIG----YEVKPSGGVFVSGGSMANLTA 150
Cdd:pfam00282  39 SPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTELENVVMNWLGEMLGlpaeFLGQEGGGVLQPGSSESNLLA 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 151 VVTARDRK-----------VTLDKLTKTTVYLTSQTHHSGRKALHVAGFpteNIRIIDHNEDFTMNVSHLKETVEKDVKN 219
Cdd:pfam00282 119 LLAARTKWikrmkaagkpaDSSGILAKLVAYTSDQAHSSIEKAALYGGV---KLREIPSDDNGKMRGMDLEKAIEEDKEN 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 220 GYIPALVISTAGTTNTGAVDDFNKIADICEAYNIWQHVDGAYGASHLLSTKGKSLFKGIERSDSVTWDAHKLLFQTYSCA 299
Cdd:pfam00282 196 GLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAYGGSAFICPEFRHWLFGIERADSITFNPHKWMLVLLDCS 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 300 MIIVKDKNNLINSYGEKAEYLDDITSDDDVIDpemLGIELTRPARAVKLWLTLQVIGEDEFRKRIDYGQELAEYTKEYVE 379
Cdd:pfam00282 276 AVWVKDKEALQQAFQFNPLYLGHTDSAYDTGH---KQIPLSRRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIR 352

                         330       340
                  ....*....|....*....|
gi 2074466784 380 SLENFEIISQPSLSILSFRY 399
Cdd:pfam00282 353 KDGRFEICAEVGLGLVCFRL 372
PLN02880 PLN02880
tyrosine decarboxylase
 49-455 2.05e-49

tyrosine decarboxylase


Pssm-ID: 215475 [Multi-domain]  Cd Length: 490  Bit Score: 175.87  E-value: 2.05e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  49 PKTGRDIYEVLSELNNEVL---TYLYRPNHkraFSFIPGPASRLSWLGDILTTANNIhaSNFKNATLPISIERNLInyLA 125
Cdd:PLN02880   56 PNQPETLDQVLDDVQAKILpgvTHWQSPNY---FAYYPSNSSVAGFLGEMLSAGLNI--VGFSWITSPAATELEMI--VL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 126 DKIGYEVK-PS--------GGVFVSGGSMANLTAVVTARD---RKVTLDKLTKTTVYLTSQTHHSGRKALHVAGFPTENI 193
Cdd:PLN02880  129 DWLAKLLNlPEqflstgngGGVIQGTASEAVLVVLLAARDrvlRKVGKNALEKLVVYASDQTHSALQKACQIAGIHPENC 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 194 RII--DHNEDFTMNVSHLKETVEKDVKNGYIPALVISTAGTTNTGAVDDFNKIADICEAYNIWQHVDGAYGASHLLSTKG 271
Cdd:PLN02880  209 RLLktDSSTNYALAPELLSEAISTDLSSGLIPFFLCATVGTTSSTAVDPLLELGKIAKSNGMWFHVDAAYAGSACICPEY 288

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 272 KSLFKGIERSDSVTWDAHKLLFQTYSCAMIIVKDKNNLINSYGEKAEYLDDITSD-DDVIDPEMLGIELTRPARAVKLWL 350
Cdd:PLN02880  289 RHYIDGVEEADSFNMNAHKWFLTNFDCSLLWVKDRNALIQSLSTNPEFLKNKASQaNSVVDYKDWQIPLGRRFRSLKLWM 368

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 351 TLQVIGEDEFRKRIDYGQELAEYTKEYVESLENFEIISQPSLSILSFRYYNDSYTDEENDYLNNLAAKKLADSGYGVAYT 430
Cdd:PLN02880  369 VLRLYGVENLQSYIRNHIKLAKEFEQLVAQDSRFEVVTPRIFSLVCFRLVPPKNNEDNGNKLNHDLLDAVNSSGKIFISH 448

                         410       420
                  ....*....|....*....|....*
gi 2074466784 431 TTLNNKKVFRMCTINPETTESDVKE 455
Cdd:PLN02880  449 TVLSGKYVLRFAVGAPLTEERHVTA 473
PLN02590 PLN02590
probable tyrosine decarboxylase
 43-455 2.66e-49

probable tyrosine decarboxylase


Pssm-ID: 178200 [Multi-domain]  Cd Length: 539  Bit Score: 176.82  E-value: 2.66e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  43 YEKMPVPKTGRDIYEVLSELNNEV-------LTYLYRPNHkraFSFIPGPASRLSWLGDILTTANNIHASNFKNATLPIS 115
Cdd:PLN02590   94 YLRDMLPDSAPERPESLKELLDDVskkimpgITHWQSPSY---FAYYASSTSVAGFLGEMLNAGLSVVGFTWLTSPAATE 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 116 IERNLINYLADKIGY-----EVKPSGGVFVSGGSMANLTAVVTARDR---KVTLDKLTKTTVYLTSQTHHSGRKALHVAG 187
Cdd:PLN02590  171 LEIIVLDWLAKLLQLpdhflSTGNGGGVIQGTGCEAVLVVVLAARDRilkKVGKTLLPQLVVYGSDQTHSSFRKACLIGG 250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 188 FPTENIRII--DHNEDFTMNVSHLKETVEKDVKNGYIPALVISTAGTTNTGAVDDFNKIADICEAYNIWQHVDGAYGASH 265
Cdd:PLN02590  251 IHEENIRLLktDSSTNYGMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKYGIWLHVDAAYAGNA 330

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 266 LLSTKGKSLFKGIERSDSVTWDAHKLLFQTYSCAMIIVKDKNNLINSYGEKAEYLD-DITSDDDVIDPEMLGIELTRPAR 344
Cdd:PLN02590  331 CICPEYRKFIDGIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKTNPEYLEfKVSKKDTVVNYKDWQISLSRRFR 410

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 345 AVKLWLTLQVIGEDEFRKRIDYGQELAEYTKEYVESLENFEIISQPSLSILSFRYYNDSYTDEENDYLNNLAAKKLADSG 424
Cdd:PLN02590  411 SLKLWMVLRLYGSENLRNFIRDHVNLAKHFEDYVAQDPSFEVVTTRYFSLVCFRLAPVDGDEDQCNERNRELLAAVNSTG 490

                         410       420       430
                  ....*....|....*....|....*....|.
gi 2074466784 425 YGVAYTTTLNNKKVFRMCTINPETTESDVKE 455
Cdd:PLN02590  491 KIFISHTALSGKFVLRFAVGAPLTEEKHVTE 521
PRK02769 PRK02769
histidine decarboxylase; Provisional
 117-376 2.03e-16

histidine decarboxylase; Provisional


Pssm-ID: 235068 [Multi-domain]  Cd Length: 380  Bit Score: 80.86  E-value: 2.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 117 ERNLINYLADKIGYEVKPSGGVFVSGGSMANLTAVVTARDRKVTldkltkTTVYLTSQTHHSGRKALHVAGFPTENIRII 196
Cdd:PRK02769   67 ERDVMNFFAELFKIPFNESWGYITNGGTEGNLYGCYLARELFPD------GTLYYSKDTHYSVSKIARLLRIKSRVITSL 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 197 DHNEdftMNVSHLKETVEKdvkNGYIPALVISTAGTTNTGAVDDFNKIADICEAYNIWQ---HVDGAYGASHLLSTKGKS 273
Cdd:PRK02769  141 PNGE---IDYDDLISKIKE---NKNQPPIIFANIGTTMTGAIDNIKEIQEILKKIGIDDyyiHADAALSGMILPFVNNPP 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 274 LFKGIERSDSVTWDAHKLLFQTYSCAMIIVKDKnnlinsygekaeYLDDITSDDDVIDPEMLGIELTRPA-RAVKLWLTL 352
Cdd:PRK02769  215 PFSFADGIDSIAISGHKFIGSPMPCGIVLAKKK------------YVERISVDVDYIGSRDQTISGSRNGhTALLLWAAI 282

                         250       260
                  ....*....|....*....|....
gi 2074466784 353 QVIGEDEFRKRIDYGQELAEYTKE 376
Cdd:PRK02769  283 RSLGSKGLRQRVQHCLDMAQYAVD 306
AAT_I cd01494
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ...
 136-292 6.35e-12

Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).


Pssm-ID: 99742 [Multi-domain]  Cd Length: 170  Bit Score: 63.94  E-value: 6.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 136 GGVFVSGGSMANLTAVVTARDRKvtldkltkTTVYLTSQTHHSGRKALHVAGFPteNIRIIDHNEDFTMnvsHLKETVEK 215
Cdd:cd01494    19 KAVFVPSGTGANEAALLALLGPG--------DEVIVDANGHGSRYWVAAELAGA--KPVPVPVDDAGYG---GLDVAILE 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2074466784 216 DVKNGYIPALVISTAGTTNTGAVDDFNKIADICEAYNIWQHVDGAYGASHllsTKGKSLFKGIERSDSVTWDAHKLL 292
Cdd:cd01494    86 ELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGA---SPAPGVLIPEGGADVVTFSLHKNL 159
PLN03032 PLN03032
serine decarboxylase; Provisional
 92-380 2.71e-08

serine decarboxylase; Provisional


Pssm-ID: 166673 [Multi-domain]  Cd Length: 374  Bit Score: 55.60  E-value: 2.71e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784  92 LGDILTTAN-NIHASNFknatlpisiERNLINYLADKIGYEVKPSGGVFVSGGSMANLTAVVTARDrkvtldKLTKTTVY 170
Cdd:PLN03032   51 LGDPFIESNyGVHSRQF---------EVGVLDWFARLWELEKDEYWGYITTCGTEGNLHGILVGRE------VFPDGILY 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 171 LTSQTHHSGRKALHVAGFPTENIRIIDHNEdftMNVSHLKETVekdVKNGYIPALVISTAGTTNTGAVDDFNKIADICEA 250
Cdd:PLN03032  116 ASRESHYSVFKAARMYRMEAVKVPTLPSGE---IDYDDLERAL---AKNRDKPAILNVNIGTTVKGAVDDLDRILRILKE 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 251 YNI-----WQHVDGAYGASHL--LSTKGKSLFKgiERSDSVTWDAHKLLFQTYSCAMIIVKDKNnlINSYGEKAEYLDDi 323
Cdd:PLN03032  190 LGYtedrfYIHCDGALFGLMMpfVSRAPEVTFR--KPIGSVSVSGHKFLGCPMPCGVALTRKKH--VKALSQNVEYLNS- 264

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2074466784 324 tsdddvIDPEMLGielTRPARA-VKLWLTLQVIGEDEFRKRIDYGQELAEYTKEYVES 380
Cdd:PLN03032  265 ------RDATIMG---SRNGHApLYLWYTLRRKGYRGIKRDVQHCMRNAHYLKDRLTE 313
Aminotran_5 pfam00266
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ...
 138-397 3.40e-07

Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.


Pssm-ID: 425567 [Multi-domain]  Cd Length: 368  Bit Score: 52.25  E-value: 3.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 138 VFVSGGSMANLTAVVTARDrkvTLDKltKTTVYLTSQTHHSGRK-ALHVAGFPTENIRIIDHNEDFTMNVSHLKETVEKD 216
Cdd:pfam00266  65 IFTSGTTEAINLVALSLGR---SLKP--GDEIVITEMEHHANLVpWQELAKRTGARVRVLPLDEDGLLDLDELEKLITPK 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 217 VKngyipaLVISTAGTTNTGAVDDFNKIADICEAYNIWQHVDGAYGASHL---LSTKGkslfkgierSDSVTWDAHKLLF 293
Cdd:pfam00266 140 TK------LVAITHVSNVTGTIQPVPEIGKLAHQYGALVLVDAAQAIGHRpidVQKLG---------VDFLAFSGHKLYG 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 294 QTYSCAMIIvkdKNNLINS-----YGekAEYLDDITSDDDVIDPEMLGIELTRP--ARAVKLWLTLQVIGEDEFRKRIDY 366
Cdd:pfam00266 205 PTGIGVLYG---RRDLLEKmppllGG--GGMIETVSLQESTFADAPWKFEAGTPniAGIIGLGAALEYLSEIGLEAIEKH 279

                         250       260       270
                  ....*....|....*....|....*....|..
gi 2074466784 367 GQELAEYTKEYVESLENFEII-SQPSLSILSF 397
Cdd:pfam00266 280 EHELAQYLYERLLSLPGIRLYgPERRASIISF 311
CsdA COG0520
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
193-266 3.78e-05

Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];


Pssm-ID: 440286 [Multi-domain]  Cd Length: 396  Bit Score: 45.90  E-value: 3.78e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2074466784 193 IRIIDHNEDFTMNVSHLKETVEKDVKngyipaLVISTAGTTNTGAVDDFNKIADICEAYNIWQHVDGAYGASHL 266
Cdd:COG0520   131 VRVIPLDEDGELDLEALEALLTPRTK------LVAVTHVSNVTGTVNPVKEIAALAHAHGALVLVDGAQSVPHL 198
NifS COG1104
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino ...
 124-262 6.39e-05

Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino acid transport and metabolism];


Pssm-ID: 440721 [Multi-domain]  Cd Length: 381  Bit Score: 45.04  E-value: 6.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 124 LADKIGyeVKPSGGVFVSGGSMANLTAVV-TARDRKVTLDKLtkttvyLTSQT-HHS---GRKALHVAGFpteNIRIIDH 198
Cdd:COG1104    54 VAALLG--ADPEEIIFTSGGTEANNLAIKgAARAYRKKGKHI------ITSAIeHPAvleTARFLEKEGF---EVTYLPV 122

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2074466784 199 NEDFTMNVSHLKETVEKDVkngyipALV-ISTAgttN--TGAVDDFNKIADICEAYNIWQHVDG--AYG 262
Cdd:COG1104   123 DEDGRVDLEALEAALRPDT------ALVsVMHA---NneTGTIQPIAEIAEIAKEHGVLFHTDAvqAVG 182
SepSecS pfam05889
O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS; Early annotation suggested this family, ...
 176-265 5.05e-04

O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS; Early annotation suggested this family, SepSecS, of several eukaryotic and archaeal proteins, was involved in antigen-antibodies responses in the liver and pancreas. Structural studies show that the family is O-phosphoseryl-tRNA(Sec) selenium transferase, an enzyme involved in the synthesis of the amino acid selenocysteine (Sec). Sec is the only amino acid whose biosynthesis occurs on its cognate transfer RNA (tRNA). SepSecS catalyzes the final step in the formation of the amino acid. The early observation that autoantibodies isolated from patients with type I autoimmune hepatitis targeted a ribonucleoprotein complex containing tRNASec led to the identification and characterization of the archaeal and the human SepSecS. SepSecS forms its own branch in the family of fold-type I pyridoxal phosphate (PLP) enzymes that goes back to the last universal common ancestor which explains why the archaeal sequences Swiss:Q8TXK0 and Swiss:Q8TYR3 are annotated as being pyridoxal phosphate-dependent enzymes.


Pssm-ID: 399111  Cd Length: 389  Bit Score: 42.19  E-value: 5.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 176 HHSGRKALHVAGFpteNIRIIDHNED---FTMNVSHLKETVEKdvKNGYIPALVISTAgTTNTGAV-DDFNKIADICEAY 251
Cdd:pfam05889 111 QKSSIKAAERAGF---EPRLVETVLDgdyLITDVNDVETIIEE--KGEEVILAVLSTT-SCFAPRSpDNVKEIAKICAEY 184

                          90
                  ....*....|....
gi 2074466784 252 NIWQHVDGAYGASH 265
Cdd:pfam05889 185 DVPHLVNGAYGIQS 198
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
117-263 5.11e-04

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 42.29  E-value: 5.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 117 ERNLINYLADKIGYEVKPSGGVFVSGGSMANLTAVVTArdrkvTLDKltKTTVYLTSQTHHSGRKALHVAGFPTENIRII 196
Cdd:pfam00155  45 REALAKFLGRSPVLKLDREAAVVFGSGAGANIEALIFL-----LANP--GDAILVPAPTYASYIRIARLAGGEVVRYPLY 117

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2074466784 197 DHNeDFTMNVSHLKETVEKDVKngyipalVISTAGTTN-TGAV---DDFNKIADICEAYNIWQHVDGAYGA 263
Cdd:pfam00155 118 DSN-DFHLDFDALEAALKEKPK-------VVLHTSPHNpTGTVatlEELEKLLDLAKEHNILLLVDEAYAG 180
Beta_elim_lyase pfam01212
Beta-eliminating lyase;
118-260 9.52e-04

Beta-eliminating lyase;


Pssm-ID: 426128 [Multi-domain]  Cd Length: 288  Bit Score: 41.05  E-value: 9.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074466784 118 RNLINYLADKIGYEvkpsGGVFVSGGSMANLTA--VVTARDRKVTLDKltkttvylTSQTH-HSGRKALHVAGFpteNIR 194
Cdd:pfam01212  35 NRLEDRVAELFGKE----AALFVPSGTAANQLAlmAHCQRGDEVICGE--------PAHIHfDETGGHAELGGV---QPR 99

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2074466784 195 IIDHNEDFTMNVSHLKETVEKDVKNGYIPALVISTAGTTNTGA-----VDDFNKIADICEAYNIWQHVDGA 260
Cdd:pfam01212 100 PLDGDEAGNMDLEDLEAAIREVGADIFPPTGLISLENTHNSAGgqvvsLENLREIAALAREHGIPVHLDGA 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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