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Conserved domains on  [gi|2083946033|ref|WP_221123031|]
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C-terminal helicase domain-containing protein, partial [Pseudomonas syringae group genomosp. 3]

Protein Classification

C-terminal helicase domain-containing protein( domain architecture ID 13039296)

C-terminal helicase domain-containing protein similar to the C-terminus of DEAD/DEAH box containing ATP-dependent helicases that catalyze the unwinding of DNA or RNA

CATH:  3.40.50.300
EC:  3.6.4.-
Gene Ontology:  GO:0003676|GO:0005524
PubMed:  20206133|20225155

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SF2_C_SNF cd18793
C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) ...
 13-131 5.51e-41

C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) family includes chromatin-remodeling factors, such as CHD proteins and SMARCA proteins, recombination proteins Rad54, and many others. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


:

Pssm-ID: 350180 [Multi-domain]  Cd Length: 135  Bit Score: 134.53  E-value: 5.51e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033  13 KVRIVADLMAEL-DVDDKVILFCEYQESVATLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQDPDCRVFIGTRSAAGT 91
Cdd:cd18793    12 KLEALLELLEELrEPGEKVLIFSQFTDTLDILEEALRERGIKYLRLDGSTSSKERQKLVDRFNEDPDIRVFLLSTKAGGV 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2083946033  92 GYNLTAANYVFFLGLPWTPGLQDQAEDRAYRNGQLRMVVV 131
Cdd:cd18793    92 GLNLTAANRVILYDPWWNPAVEEQAIDRAHRIGQKKPVVV 131
 
Name Accession Description Interval E-value
SF2_C_SNF cd18793
C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) ...
 13-131 5.51e-41

C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) family includes chromatin-remodeling factors, such as CHD proteins and SMARCA proteins, recombination proteins Rad54, and many others. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350180 [Multi-domain]  Cd Length: 135  Bit Score: 134.53  E-value: 5.51e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033  13 KVRIVADLMAEL-DVDDKVILFCEYQESVATLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQDPDCRVFIGTRSAAGT 91
Cdd:cd18793    12 KLEALLELLEELrEPGEKVLIFSQFTDTLDILEEALRERGIKYLRLDGSTSSKERQKLVDRFNEDPDIRVFLLSTKAGGV 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2083946033  92 GYNLTAANYVFFLGLPWTPGLQDQAEDRAYRNGQLRMVVV 131
Cdd:cd18793    92 GLNLTAANRVILYDPWWNPAVEEQAIDRAHRIGQKKPVVV 131
HepA COG0553
Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination, ...
 9-160 6.75e-41

Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination, and repair];


Pssm-ID: 440319 [Multi-domain]  Cd Length: 682  Bit Score: 145.37  E-value: 6.75e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033   9 LERVkVRIVADLMAEldvDDKVILFCEYQESVATLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQDPDCRVFIGTRSA 88
Cdd:COG0553   535 LEAL-LELLEELLAE---GEKVLVFSQFTDTLDLLEERLEERGIEYAYLHGGTSAEERDELVDRFQEGPEAPVFLISLKA 610

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2083946033  89 AGTGYNLTAANYVFFLGLPWTPGLQDQAEDRAYRNGQLRMVVVKIPLAEDTIDQQLWQMLMDKRALASDLID 160
Cdd:COG0553   611 GGEGLNLTAADHVIHYDLWWNPAVEEQAIDRAHRIGQTRDVQVYKLVAEGTIEEKILELLEEKRALAESVLG 682
Helicase_C pfam00271
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ...
 13-124 1.96e-18

Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.


Pssm-ID: 459740 [Multi-domain]  Cd Length: 109  Bit Score: 76.10  E-value: 1.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033  13 KVRIVADLMAELDvDDKVILFCEYQESVAtLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQqDPDCRVFIGTRsAAGTG 92
Cdd:pfam00271   2 KLEALLELLKKER-GGKVLIFSQTKKTLE-AELLLEKEGIKVARLHGDLSQEEREEILEDFR-KGKIDVLVATD-VAERG 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2083946033  93 YNLTAANYVFFLGLPWTPGLQDQAEDRAYRNG 124
Cdd:pfam00271  78 LDLPDVDLVINYDLPWNPASYIQRIGRAGRAG 109
HELICc smart00490
helicase superfamily c-terminal domain;
42-124 8.83e-13

helicase superfamily c-terminal domain;


Pssm-ID: 197757 [Multi-domain]  Cd Length: 82  Bit Score: 60.69  E-value: 8.83e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033   42 TLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQDpDCRVFIGTrSAAGTGYNLTAANYVFFLGLPWTPGLQDQAEDRAY 121
Cdd:smart00490   2 ELAELLKELGIKVARLHGGLSQEEREEILDKFNNG-KIKVLVAT-DVAERGLDLPGVDLVIIYDLPWSPASYIQRIGRAG 79


                   ...
gi 2083946033  122 RNG 124
Cdd:smart00490  80 RAG 82
PLN03142 PLN03142
Probable chromatin-remodeling complex ATPase chain; Provisional
 5-154 1.12e-08

Probable chromatin-remodeling complex ATPase chain; Provisional


Pssm-ID: 215601 [Multi-domain]  Cd Length: 1033  Bit Score: 53.27  E-value: 1.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033    5 LRQLLERVKVRivadlmaeldvDDKVILFCEYQESVATLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQdPDCRVFI- 83
Cdd:PLN03142   476 LDKLLPKLKER-----------DSRVLIFSQMTRLLDILEDYLMYRGYQYCRIDGNTGGEDRDASIDAFNK-PGSEKFVf 543

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2083946033   84 --GTRsAAGTGYNLTAANYVFFLGLPWTPGLQDQAEDRAYRNGQLRMVVVKIPLAEDTIDQQLWQMLMDKRAL 154
Cdd:PLN03142   544 llSTR-AGGLGINLATADIVILYDSDWNPQVDLQAQDRAHRIGQKKEVQVFRFCTEYTIEEKVIERAYKKLAL 615
 
Name Accession Description Interval E-value
SF2_C_SNF cd18793
C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) ...
 13-131 5.51e-41

C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) family includes chromatin-remodeling factors, such as CHD proteins and SMARCA proteins, recombination proteins Rad54, and many others. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350180 [Multi-domain]  Cd Length: 135  Bit Score: 134.53  E-value: 5.51e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033  13 KVRIVADLMAEL-DVDDKVILFCEYQESVATLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQDPDCRVFIGTRSAAGT 91
Cdd:cd18793    12 KLEALLELLEELrEPGEKVLIFSQFTDTLDILEEALRERGIKYLRLDGSTSSKERQKLVDRFNEDPDIRVFLLSTKAGGV 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2083946033  92 GYNLTAANYVFFLGLPWTPGLQDQAEDRAYRNGQLRMVVV 131
Cdd:cd18793    92 GLNLTAANRVILYDPWWNPAVEEQAIDRAHRIGQKKPVVV 131
HepA COG0553
Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination, ...
 9-160 6.75e-41

Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination, and repair];


Pssm-ID: 440319 [Multi-domain]  Cd Length: 682  Bit Score: 145.37  E-value: 6.75e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033   9 LERVkVRIVADLMAEldvDDKVILFCEYQESVATLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQDPDCRVFIGTRSA 88
Cdd:COG0553   535 LEAL-LELLEELLAE---GEKVLVFSQFTDTLDLLEERLEERGIEYAYLHGGTSAEERDELVDRFQEGPEAPVFLISLKA 610

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2083946033  89 AGTGYNLTAANYVFFLGLPWTPGLQDQAEDRAYRNGQLRMVVVKIPLAEDTIDQQLWQMLMDKRALASDLID 160
Cdd:COG0553   611 GGEGLNLTAADHVIHYDLWWNPAVEEQAIDRAHRIGQTRDVQVYKLVAEGTIEEKILELLEEKRALAESVLG 682
Helicase_C pfam00271
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ...
 13-124 1.96e-18

Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.


Pssm-ID: 459740 [Multi-domain]  Cd Length: 109  Bit Score: 76.10  E-value: 1.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033  13 KVRIVADLMAELDvDDKVILFCEYQESVAtLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQqDPDCRVFIGTRsAAGTG 92
Cdd:pfam00271   2 KLEALLELLKKER-GGKVLIFSQTKKTLE-AELLLEKEGIKVARLHGDLSQEEREEILEDFR-KGKIDVLVATD-VAERG 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2083946033  93 YNLTAANYVFFLGLPWTPGLQDQAEDRAYRNG 124
Cdd:pfam00271  78 LDLPDVDLVINYDLPWNPASYIQRIGRAGRAG 109
HELICc smart00490
helicase superfamily c-terminal domain;
42-124 8.83e-13

helicase superfamily c-terminal domain;


Pssm-ID: 197757 [Multi-domain]  Cd Length: 82  Bit Score: 60.69  E-value: 8.83e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033   42 TLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQDpDCRVFIGTrSAAGTGYNLTAANYVFFLGLPWTPGLQDQAEDRAY 121
Cdd:smart00490   2 ELAELLKELGIKVARLHGGLSQEEREEILDKFNNG-KIKVLVAT-DVAERGLDLPGVDLVIIYDLPWSPASYIQRIGRAG 79


                   ...
gi 2083946033  122 RNG 124
Cdd:smart00490  80 RAG 82
SSL2 COG1061
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
10-104 9.34e-10

Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];


Pssm-ID: 440681 [Multi-domain]  Cd Length: 566  Bit Score: 56.57  E-value: 9.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033  10 ERVKVRIVADLMAELDVDDKVILFCEYQESVATLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQDPDcrVFIGTRSAA 89
Cdd:COG1061   288 AERKDKILRELLREHPDDRKTLVFCSSVDHAEALAELLNEAGIRAAVVTGDTPKKEREEILEAFRDGEL--RILVTVDVL 365

                          90
                  ....*....|....*
gi 2083946033  90 GTGYNLTAANYVFFL 104
Cdd:COG1061   366 NEGVDVPRLDVAILL 380
PLN03142 PLN03142
Probable chromatin-remodeling complex ATPase chain; Provisional
 5-154 1.12e-08

Probable chromatin-remodeling complex ATPase chain; Provisional


Pssm-ID: 215601 [Multi-domain]  Cd Length: 1033  Bit Score: 53.27  E-value: 1.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2083946033    5 LRQLLERVKVRivadlmaeldvDDKVILFCEYQESVATLREHCLKMGIGCVTLVGSDSPKKRQKAIDAFQQdPDCRVFI- 83
Cdd:PLN03142   476 LDKLLPKLKER-----------DSRVLIFSQMTRLLDILEDYLMYRGYQYCRIDGNTGGEDRDASIDAFNK-PGSEKFVf 543

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2083946033   84 --GTRsAAGTGYNLTAANYVFFLGLPWTPGLQDQAEDRAYRNGQLRMVVVKIPLAEDTIDQQLWQMLMDKRAL 154
Cdd:PLN03142   544 llSTR-AGGLGINLATADIVILYDSDWNPQVDLQAQDRAHRIGQKKEVQVFRFCTEYTIEEKVIERAYKKLAL 615
SF2_C_DEAD cd18787
C-terminal helicase domain of the DEAD box helicases; DEAD-box helicases comprise a diverse ...
 5-73 3.11e-05

C-terminal helicase domain of the DEAD box helicases; DEAD-box helicases comprise a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis, and RNA degradation. They are superfamily (SF)2 helicases that, similar to SF1, do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350174 [Multi-domain]  Cd Length: 131  Bit Score: 41.72  E-value: 3.11e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2083946033   5 LRQLLERV----KVRIVADLMAELDVDDKVILFCEYQESVATLREHCLKMGIGCVTLVGSDSPKKRQKAIDAF 73
Cdd:cd18787     1 IKQLYVVVeeeeKKLLLLLLLLEKLKPGKAIIFVNTKKRVDRLAELLEELGIKVAALHGDLSQEERERALKKF 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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