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Conserved domains on  [gi|2085393401|ref|WP_221679771|]
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DeoR/GlpR family DNA-binding transcription regulator [Enterococcus sp. K18_3]

Protein Classification

DeoR/GlpR family DNA-binding transcription regulator( domain architecture ID 11442564)

DeoR/GlpR family DNA-binding transcription regulator is a helix-turn-helix type transcriptional regulator that may be involved in sugar metabolism

Gene Ontology:  GO:0003700|GO:0003677
PubMed:  15808743

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-235 7.57e-83

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


:

Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 248.13  E-value: 7.57e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   1 MLKKERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQKLEKIEQELSTQEKIDTNVPEKK 80
Cdd:COG1349     1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  81 FIGKVMNSIISDNDTIYIGAGTTMLHALPEIK-KANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIAEKS 159
Cdd:COG1349    81 AIARAAASLIEDGDTIFLDAGTTTLALARALPdRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2085393401 160 FDNLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDNKLPD 235
Cdd:COG1349   161 LRRFRADKAFLGASGIdAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPP 237
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-235 7.57e-83

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 248.13  E-value: 7.57e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   1 MLKKERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQKLEKIEQELSTQEKIDTNVPEKK 80
Cdd:COG1349     1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  81 FIGKVMNSIISDNDTIYIGAGTTMLHALPEIK-KANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIAEKS 159
Cdd:COG1349    81 AIARAAASLIEDGDTIFLDAGTTTLALARALPdRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2085393401 160 FDNLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDNKLPD 235
Cdd:COG1349   161 LRRFRADKAFLGASGIdAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPP 237
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 74-230 2.95e-47

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 154.21  E-value: 2.95e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  74 TNVPEKKFIGKVMNSIISDNDTIYIGAGTTMLHALPEI-KKANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFY 152
Cdd:pfam00455   1 ENAEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALpDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFV 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2085393401 153 GEIAEKSFDNLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTD 230
Cdd:pfam00455  81 GPLAEEFLRQFNVDKAFIGANGIdLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITD 159
srlR PRK10434
DNA-binding transcriptional repressor;
1-235 1.19e-38

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 135.20  E-value: 1.19e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   1 MLKKERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQkLEKIEQELSTQEKIDTNVPEKK 80
Cdd:PRK10434    1 MKPRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVV-LNKEESDPPIDHKTLINTHKKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  81 FIGKVMNSIISDNDTIYIGAGTTMLHALPEIKK-ANLFVITNSLLAFNYLI-YNTDYRVLLTGGEFSRTTEEFYGEIAEK 158
Cdd:PRK10434   80 LIAEAAVSLIHDGDSIILDAGSTVLQMVPLLSRfNNITVMTNSLHIVNALSeLDNEQTILMPGGTFRKKSASFHGQLAEN 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2085393401 159 SFDNLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAhSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDNKLPD 235
Cdd:PRK10434  160 AFEHFTFDKLFIGTDGIdLNAGVTTFNEVYTVSKAMCNA-AREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDP 236
AgaR NF040755
transcriptional repressor AgaR;
5-235 3.52e-32

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 118.14  E-value: 3.52e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   5 ERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQKLEKI--EQELSTQEKIDTNVPEKKFI 82
Cdd:NF040755    6 ERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFipGAEPSVEDKSRLNTAVKRLI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  83 GKVMNSIISDNDTIYIGAGTTMLHALPEIK-KANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIAEKSFD 161
Cdd:NF040755   86 AAAAAELIKPGDRVILDSGTTTYEIARHLKqHQDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAEQSLQ 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2085393401 162 NLNIDIAFAATNGvFDNN--VTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDNKLPD 235
Cdd:NF040755  166 NYHFDKLFLGVDG-FDLErgITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPE 240
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
6-57 2.10e-16

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 71.10  E-value: 2.10e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2085393401    6 RQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQ 57
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAV 52
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-235 7.57e-83

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 248.13  E-value: 7.57e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   1 MLKKERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQKLEKIEQELSTQEKIDTNVPEKK 80
Cdd:COG1349     1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  81 FIGKVMNSIISDNDTIYIGAGTTMLHALPEIK-KANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIAEKS 159
Cdd:COG1349    81 AIARAAASLIEDGDTIFLDAGTTTLALARALPdRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2085393401 160 FDNLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDNKLPD 235
Cdd:COG1349   161 LRRFRADKAFLGASGIdAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPP 237
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 74-230 2.95e-47

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 154.21  E-value: 2.95e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  74 TNVPEKKFIGKVMNSIISDNDTIYIGAGTTMLHALPEI-KKANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFY 152
Cdd:pfam00455   1 ENAEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALpDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFV 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2085393401 153 GEIAEKSFDNLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTD 230
Cdd:pfam00455  81 GPLAEEFLRQFNVDKAFIGANGIdLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITD 159
srlR PRK10434
DNA-binding transcriptional repressor;
1-235 1.19e-38

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 135.20  E-value: 1.19e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   1 MLKKERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQkLEKIEQELSTQEKIDTNVPEKK 80
Cdd:PRK10434    1 MKPRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVV-LNKEESDPPIDHKTLINTHKKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  81 FIGKVMNSIISDNDTIYIGAGTTMLHALPEIKK-ANLFVITNSLLAFNYLI-YNTDYRVLLTGGEFSRTTEEFYGEIAEK 158
Cdd:PRK10434   80 LIAEAAVSLIHDGDSIILDAGSTVLQMVPLLSRfNNITVMTNSLHIVNALSeLDNEQTILMPGGTFRKKSASFHGQLAEN 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2085393401 159 SFDNLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAhSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDNKLPD 235
Cdd:PRK10434  160 AFEHFTFDKLFIGTDGIdLNAGVTTFNEVYTVSKAMCNA-AREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDP 236
AgaR NF040755
transcriptional repressor AgaR;
5-235 3.52e-32

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 118.14  E-value: 3.52e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   5 ERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQKLEKI--EQELSTQEKIDTNVPEKKFI 82
Cdd:NF040755    6 ERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFipGAEPSVEDKSRLNTAVKRLI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  83 GKVMNSIISDNDTIYIGAGTTMLHALPEIK-KANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIAEKSFD 161
Cdd:NF040755   86 AAAAAELIKPGDRVILDSGTTTYEIARHLKqHQDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAEQSLQ 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2085393401 162 NLNIDIAFAATNGvFDNN--VTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDNKLPD 235
Cdd:NF040755  166 NYHFDKLFLGVDG-FDLErgITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPE 240
PRK09802 PRK09802
DeoR family transcriptional regulator;
5-235 4.09e-29

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 110.71  E-value: 4.09e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   5 ERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQKLEKIE--QELSTQEKIDTNVPEKKFI 82
Cdd:PRK09802   17 ERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTpsVEPSVEDKSALNTAMKRSV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  83 GKVMNSIISDNDTIYIGAGTTMLHALPEIKK-ANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIAEKSFD 161
Cdd:PRK09802   97 AKAAVELIQPGHRVILDSGTTTFEIARLMRKhTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSLQ 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2085393401 162 NLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDNKLPD 235
Cdd:PRK09802  177 NYHFDMLFLGVDAIdLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPA 251
PRK10906 PRK10906
DeoR/GlpR family transcriptional regulator;
1-234 6.20e-27

DeoR/GlpR family transcriptional regulator;


Pssm-ID: 182827 [Multi-domain]  Cd Length: 252  Bit Score: 104.56  E-value: 6.20e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   1 MLKKERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAqKLEKIEQELSTQEKIDTNVPEKK 80
Cdd:PRK10906    1 MKQTQRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGA-ALPSSSVNTPWHDRKATQTEEKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  81 FIGKVMNSIISDNDTIYIGAGTT---MLHALpeIKKANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIAE 157
Cdd:PRK10906   80 RIARKVASQIPNGATLFIDIGTTpeaVAHAL--LNHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATL 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2085393401 158 KSFDNLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDNKLP 234
Cdd:PRK10906  158 DFISQFRLDFGILGISGIdSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDQLPP 235
PRK13509 PRK13509
HTH-type transcriptional regulator UlaR;
1-231 6.88e-22

HTH-type transcriptional regulator UlaR;


Pssm-ID: 184100 [Multi-domain]  Cd Length: 251  Bit Score: 90.84  E-value: 6.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   1 MLKKERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQKLEKiEQELSTQEKID--TNVPE 78
Cdd:PRK13509    1 MTEAQRHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGAEAITQ-QRPRWTPMNIHqaQNHDE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  79 KKFIGKVMNSIISDNDTIYIGAGTTMLHALPEIKKANLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIAEK 158
Cdd:PRK13509   80 KVRIAKAASQLCNPGESVVINCGSTAFLLGRELCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSE 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2085393401 159 SFDNLNiDIAFAA-----TNGVFDNNVTSANSIEGSIQRVAfahsrKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDN 231
Cdd:PRK13509  160 NSLYAG-HWMFTSgkgltADGLYKTDMLTAMAEQKMLSVVG-----KLVVLVDSSKIGERAGMLFSRADQIDMLITGK 231
PRK10681 PRK10681
DNA-binding transcriptional repressor DeoR; Provisional
 5-247 2.82e-20

DNA-binding transcriptional repressor DeoR; Provisional


Pssm-ID: 182644 [Multi-domain]  Cd Length: 252  Bit Score: 86.67  E-value: 2.82e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   5 ERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINEladKSLLVKIYGGAQKLEKIEQE---LSTQEKidTNVPEKKF 81
Cdd:PRK10681    7 ERIGQLLQALKRSDKLHLKDAAALLGVSEMTIRRDLNA---HSAPVVLLGGYIVLEPRSAShylLSDQKS--RLVEEKRR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  82 IGKVMNSIISDNDTIYIGAGTTMLHALPEIKKANLFV-ITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIAEKSF 160
Cdd:PRK10681   82 AAQLAATLVEPNQTLFFDCGTTTPWIIEAIDNELPFTaVCYSLNTFLALQEKPHCRAILCGGEFHASNAIFKPLDFQQTL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401 161 DNLNIDIAFAATNGV-FDNNVTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTDnKLPDTQFD 239
Cdd:PRK10681  162 DNICPDIAFYSAAGVhVSKGATCFNLEELPVKHWAMAMAQKHVLVVDHSKFGKVRPARMGDLTRFDTVVSD-RCPDDEFV 240


                  ....*...
gi 2085393401 240 YYSSYTKI 247
Cdd:PRK10681  241 KYAQAQRI 248
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
6-57 2.10e-16

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 71.10  E-value: 2.10e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2085393401    6 RQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQ 57
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAV 52
HTH_DeoR pfam08220
DeoR-like helix-turn-helix domain;
6-61 2.23e-16

DeoR-like helix-turn-helix domain;


Pssm-ID: 285436 [Multi-domain]  Cd Length: 57  Bit Score: 71.14  E-value: 2.23e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2085393401   6 RQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQKLEK 61
Cdd:pfam08220   1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSNSS 56
PRK10411 PRK10411
L-fucose operon activator;
2-230 2.92e-13

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 67.14  E-value: 2.92e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401   2 LKKERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLVKIYGGAQKLEKIEQELST--QEKIDTNVPEK 79
Cdd:PRK10411    1 MKAARQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDpfHIRLKSHYAHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2085393401  80 KFIGKVMNSIISDNDTIYIGAGTTMLH---ALPEIkkaNLFVITNSLLAFNYLIYNTDYRVLLTGGEFSRTTEEFYGEIA 156
Cdd:PRK10411   81 ADIAREALAWIEEGMVIALDASSTCWYlarQLPDI---NIQVFTNSHPICQELGKRERIQLISSGGTLERKYGCYVNPSL 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2085393401 157 EKSFDNLNIDIAFAATNGVFD-NNVTSANSIEGSIQRVAFAHSRKKCVVADSSKFNRSDVYTFYSLSEVDYLVTD 230
Cdd:PRK10411  158 ISQLKSLEIDLFIFSCEGIDSsGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISD 232
HTH_11 pfam08279
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.
 8-54 3.92e-05

HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.


Pssm-ID: 429896 [Multi-domain]  Cd Length: 52  Bit Score: 40.11  E-value: 3.92e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2085393401   8 EKILDLLNRND-YLSIPEISSSLDVSDMTIRRDINELadKSLLVKIYG 54
Cdd:pfam08279   1 LQILQLLLEARgPISGQELAEKLGVSRRTIRRDIKIL--EELGVPIEA 46
YobV COG2378
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains ...
 5-45 1.13e-04

Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains [Transcription];


Pssm-ID: 441945 [Multi-domain]  Cd Length: 314  Bit Score: 42.76  E-value: 1.13e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2085393401   5 ERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELAD 45
Cdd:COG2378     5 ERLLALLQLLQSRRGVTAAELAERLEVSERTIYRDIDALRE 45
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
2-50 5.14e-03

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 37.21  E-value: 5.14e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2085393401   2 LKKERQEKILDLLNRNDYLSIPEISSSLDVSDMTIRRDINELADKSLLV 50
Cdd:COG2345    10 LADPTRRRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVE 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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