|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-470 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 709.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 1 MSKKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFEN 80
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 81 GGCNFVEGDEIDLVKDEVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNLP 160
Cdd:COG0469 81 GPVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 161 GIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDmIQIFPKIENQEGFDNIREILEVADGVM 240
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGR-APIIAKIEKPEAVENLDEIIEASDGIM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 241 VARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYP 320
Cdd:COG0469 240 VARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYP 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 321 VESVQTMTKIANAIEPMIPYKDRLKANVKSSKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPILAV 400
Cdd:COG0469 320 VEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILAL 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2088970467 401 TFDEVTQRSLLPVNGVTPVVSNIQNNKENDIDLARNLALQAGF-KTGDHIIVVAGYPIG-SGNTNMMRIAQI 470
Cdd:COG0469 400 TPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLvKPGDLVVITAGVPVGvPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-458 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 585.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 1 MSKKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFEN 80
Cdd:PRK05826 2 MLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 81 GGCNFVEGDEIDLV-KDEVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNL 159
Cdd:PRK05826 82 GKITLKTGDKFTLDtDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 160 PGIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDMIQIFPKIENQEGFDNIREILEVADGV 239
Cdd:PRK05826 162 PGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPHAKIIAKIERAEAVDNIDEIIEASDGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 240 MVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHY 319
Cdd:PRK05826 242 MVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKY 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 320 PVESVQTMTKIANAIEPMiPYKDRLKANVKSSKRTLNDAIGISVADTALAI-DIKCIIAFTQSGNTARRLAKFRPCAPIL 398
Cdd:PRK05826 322 PVEAVEAMARICKGAEKE-FSINLSKHRLDRQFDRIDEAIAMSAMYAANHLkGVKAIVALTESGRTARLISRFRPGAPIF 400
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2088970467 399 AVTFDEVTQRSLLPVNGVTPV-VSNIQNNKENDIDLARNLALQAGFKTGDHIIVVAGYPIG 458
Cdd:PRK05826 401 AVTRDEKTQRRLALYRGVYPVlFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMG 461
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
3-467 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 558.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 3 KKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGG 82
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 83 -CNFVEGDEIDLVKDE--VLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGV-VNNPHFLKSRKGCN 158
Cdd:cd00288 82 dISLKAGDKFLVTTDPaaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKTLVCeVLNGGVLGSRKGVN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 159 LPGIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDmIQIFPKIENQEGFDNIREILEVADG 238
Cdd:cd00288 162 LPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKD-IKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 239 VMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGH 318
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 319 YPVESVQTMTKIANAIEPMIPYKDRLKANVKSSKRTLN--DAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAP 396
Cdd:cd00288 321 YPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSttEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAP 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2088970467 397 ILAVTFDEVTQRSLLPVNGVTPVV-----SNIQNNKENDIDLARNLALQAGF-KTGDHIIVVAGYPIGSGNTNMMRI 467
Cdd:cd00288 401 IIAVTRNEQTARQLHLYRGVYPVLfeepkPGWQEDTDARLKAAVNVAKEKGLlKKGDLVVVVQGWPVGSGSTNTMRI 477
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
3-467 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 553.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 3 KKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGG 82
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 83 CNFVEGDEIDLVKD--EVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNLP 160
Cdd:TIGR01064 81 VKLKKGDKVIITTDdiKGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 161 GIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDMIQIFPKIENQEGFDNIREILEVADGVM 240
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 241 VARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYP 320
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 321 VESVQTMTKIANAIEPMIPYKDRLK--ANVKSSKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPIL 398
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNdrKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2088970467 399 AVTFDEVTQRSLLPVNGVTPVVSniqNNKENDIDLARNLALQAG-----FKTGDHIIVVAGYPIG-SGNTNMMRI 467
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLV---DEEPSDTDARVNKALELLkekgiVKKGDLVVVIQGGPIGgEGGTNTIRV 472
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
3-344 |
1.91e-151 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 434.87 E-value: 1.91e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 3 KKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGG 82
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 83 CNF--VEGDEIDLVKDEVL---GNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPD-RIHGVVNNPHFLKSRKG 156
Cdd:pfam00224 82 KDIelKAGDEMIVSTDAKYkgaCDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRKG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 157 CNLPGIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDmIQIFPKIENQEGFDNIREILEVA 236
Cdd:pfam00224 162 VNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKN-IQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 237 DGVMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAA 316
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|....*...
gi 2088970467 317 GHYPVESVQTMTKIANAIEPMIPYKDRL 344
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-470 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 709.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 1 MSKKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFEN 80
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 81 GGCNFVEGDEIDLVKDEVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNLP 160
Cdd:COG0469 81 GPVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 161 GIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDmIQIFPKIENQEGFDNIREILEVADGVM 240
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGR-APIIAKIEKPEAVENLDEIIEASDGIM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 241 VARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYP 320
Cdd:COG0469 240 VARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYP 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 321 VESVQTMTKIANAIEPMIPYKDRLKANVKSSKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPILAV 400
Cdd:COG0469 320 VEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILAL 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2088970467 401 TFDEVTQRSLLPVNGVTPVVSNIQNNKENDIDLARNLALQAGF-KTGDHIIVVAGYPIG-SGNTNMMRIAQI 470
Cdd:COG0469 400 TPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLvKPGDLVVITAGVPVGvPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-458 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 585.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 1 MSKKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFEN 80
Cdd:PRK05826 2 MLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 81 GGCNFVEGDEIDLV-KDEVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNL 159
Cdd:PRK05826 82 GKITLKTGDKFTLDtDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 160 PGIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDMIQIFPKIENQEGFDNIREILEVADGV 239
Cdd:PRK05826 162 PGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPHAKIIAKIERAEAVDNIDEIIEASDGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 240 MVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHY 319
Cdd:PRK05826 242 MVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKY 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 320 PVESVQTMTKIANAIEPMiPYKDRLKANVKSSKRTLNDAIGISVADTALAI-DIKCIIAFTQSGNTARRLAKFRPCAPIL 398
Cdd:PRK05826 322 PVEAVEAMARICKGAEKE-FSINLSKHRLDRQFDRIDEAIAMSAMYAANHLkGVKAIVALTESGRTARLISRFRPGAPIF 400
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2088970467 399 AVTFDEVTQRSLLPVNGVTPV-VSNIQNNKENDIDLARNLALQAGFKTGDHIIVVAGYPIG 458
Cdd:PRK05826 401 AVTRDEKTQRRLALYRGVYPVlFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMG 461
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-467 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 580.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 1 MSKKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFEN 80
Cdd:PRK06354 6 LMRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFED 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 81 GGCNFVEGDEIDLVKDEVLGNHERFTLRCPEVFNDVKVGDYILMDDGK--MKVTFTEVTPDRIHGVVNNPHFLKSRKGCN 158
Cdd:PRK06354 86 GPIELKTGDEFILTSREVLGTQEKFSVTYDGLADEVPVGSRILLDDGLieLEVEEVDKADGELHCKVLVGGVLSNKKGVN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 159 LPGIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDMIQIFPKIENQEGFDNIREILEVADG 238
Cdd:PRK06354 166 FPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNGKHIPIIAKIEKQEAIDNIDAILELCDG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 239 VMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGH 318
Cdd:PRK06354 246 LMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGD 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 319 YPVESVQTMTKIANAIEPMIPYKDRLkANVKSSKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPIL 398
Cdd:PRK06354 326 YPVEAVQTMATIAVRIEKDLPYRDIL-SKRPEFTTTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTPIL 404
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2088970467 399 AVTFDEVTQRSLLPVNGVTPVVSNIQNNKENDIDLARNLALQAGF-KTGDHIIVVAGYPIG-SGNTNMMRI 467
Cdd:PRK06354 405 AVTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLlKQGDLVVITAGTLVGeSGSTDLMKV 475
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
3-467 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 558.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 3 KKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGG 82
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 83 -CNFVEGDEIDLVKDE--VLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGV-VNNPHFLKSRKGCN 158
Cdd:cd00288 82 dISLKAGDKFLVTTDPaaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKTLVCeVLNGGVLGSRKGVN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 159 LPGIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDmIQIFPKIENQEGFDNIREILEVADG 238
Cdd:cd00288 162 LPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKD-IKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 239 VMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGH 318
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 319 YPVESVQTMTKIANAIEPMIPYKDRLKANVKSSKRTLN--DAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAP 396
Cdd:cd00288 321 YPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSttEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAP 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2088970467 397 ILAVTFDEVTQRSLLPVNGVTPVV-----SNIQNNKENDIDLARNLALQAGF-KTGDHIIVVAGYPIGSGNTNMMRI 467
Cdd:cd00288 401 IIAVTRNEQTARQLHLYRGVYPVLfeepkPGWQEDTDARLKAAVNVAKEKGLlKKGDLVVVVQGWPVGSGSTNTMRI 477
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
3-467 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 553.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 3 KKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGG 82
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 83 CNFVEGDEIDLVKD--EVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNLP 160
Cdd:TIGR01064 81 VKLKKGDKVIITTDdiKGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 161 GIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDMIQIFPKIENQEGFDNIREILEVADGVM 240
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 241 VARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYP 320
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 321 VESVQTMTKIANAIEPMIPYKDRLK--ANVKSSKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPIL 398
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNdrKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2088970467 399 AVTFDEVTQRSLLPVNGVTPVVSniqNNKENDIDLARNLALQAG-----FKTGDHIIVVAGYPIG-SGNTNMMRI 467
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLV---DEEPSDTDARVNKALELLkekgiVKKGDLVVVIQGGPIGgEGGTNTIRV 472
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
3-470 |
2.48e-180 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 512.68 E-value: 2.48e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 3 KKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGG 82
Cdd:PRK09206 2 KKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGGN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 83 -CNFVEGDEIDLVKD-EVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNLP 160
Cdd:PRK09206 82 dVSLKAGQTFTFTTDkSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNLP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 161 GIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDMIQIFPKIENQEGFDNIREILEVADGVM 240
Cdd:PRK09206 162 GVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGIM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 241 VARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYP 320
Cdd:PRK09206 242 VARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 321 VESVQTMTKIANAIEPMIPykDRLKANVKSSKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPILAV 400
Cdd:PRK09206 322 LEAVSIMATICERTDRVMN--SRLESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATILAL 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2088970467 401 TFDEVTQRSLLPVNGVTPVVSNIQNNKENDIDLARNLALQAGF-KTGDHIIVVAGYPIGSGNTNMMRIAQI 470
Cdd:PRK09206 400 TTNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLaQKGDVVVMVSGALVPSGTTNTASVHVL 470
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
1-470 |
1.62e-177 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 506.00 E-value: 1.62e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 1 MSKKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFEN 80
Cdd:PRK06247 3 RNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFAD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 81 GGCNFVEGDEIDLVKDEVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNLP 160
Cdd:PRK06247 83 GKVQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 161 GIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILidenKDMIQIFPKIENQEGFDNIREILEVADGVM 240
Cdd:PRK06247 163 GTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKII----GGRVPVMAKIEKPQAIDRLEAIVEASDAIM 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 241 VARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYP 320
Cdd:PRK06247 239 VARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 321 VESVQTMTKIANAIEPMIPYKDRLKANVKSSKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPILAV 400
Cdd:PRK06247 319 VEAVRTMARIIRQVERDPTYPPLIHAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILAL 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2088970467 401 TFDEVTQRSLLPVNGVTPVVSNIQNNKENDIDLARNLALQAGF-KTGDHIIVVAGYPIG-SGNTNMMRIAQI 470
Cdd:PRK06247 399 TPNPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFyKRGDRVVIVAGVPPGtPGSTNMLRIAYI 470
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
3-344 |
1.91e-151 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 434.87 E-value: 1.91e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 3 KKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGG 82
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 83 CNF--VEGDEIDLVKDEVL---GNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPD-RIHGVVNNPHFLKSRKG 156
Cdd:pfam00224 82 KDIelKAGDEMIVSTDAKYkgaCDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRKG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 157 CNLPGIKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDmIQIFPKIENQEGFDNIREILEVA 236
Cdd:pfam00224 162 VNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKN-IQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 237 DGVMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAA 316
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|....*...
gi 2088970467 317 GHYPVESVQTMTKIANAIEPMIPYKDRL 344
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
2-470 |
1.85e-141 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 415.31 E-value: 1.85e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 2 SKKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKEtgKP---IGILLDTKGPEIRLGDF 78
Cdd:PTZ00066 37 QKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKA--RPnanLGILLDTKGPEIRTGFL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 79 ENGG-CNFVEGDEIDLVKD-EVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKG 156
Cdd:PTZ00066 115 KNHKpITLKEGQTLKITTDyTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKN 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 157 CNLPGIKLSMPFISEKDESDI-RFGCKMDVDYIAASFTRRKDDVLAIRQILiDENKDMIQIFPKIENQEGFDNIREILEV 235
Cdd:PTZ00066 195 MNLPGVKVELPVIGEKDKNDIlNFAIPMGCDFIALSFVQSADDVRLCRQLL-GERGRHIKIIPKIENIEGLINFDEILAE 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 236 ADGVMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESA 315
Cdd:PTZ00066 274 SDGIMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETA 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 316 AGHYPVESVQTMTKIANAIEPMIPYKDRLKANVKS--SKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRP 393
Cdd:PTZ00066 354 NGKFPVEAVNIMAKICFEAETCIDYRVLYHAIHLAvpTPVSVQEAVARSAVETAEDINAKLIIALTETGNTARLISKYRP 433
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2088970467 394 CAPILAVTFDEVTQRSLLPVNGVTPVVSNIQNNKENDIDLARNLALQAGF-KTGDHIIVVAGYPIG-SGNTNMMRIAQI 470
Cdd:PTZ00066 434 SCTILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLvESGDSAIAVHGVKEEvAGSSNLMKVVKI 512
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
3-470 |
1.55e-139 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 410.52 E-value: 1.55e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 3 KKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGG 82
Cdd:PLN02461 21 PKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFLKDGK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 83 -CNFVEGDEIDLVKD-EVLGNHERFTLRCPEVFNDVKVGDYILMDDGKmkVTFTEVTPDRIHGVVN----NPHFLKSRKG 156
Cdd:PLN02461 101 pVQLKQGQEITITTDySIKGDENMIAMSYKKLAVDVKPGSVILCADGT--ITLTVLSCDVEAGTVRcrceNSAMLGERKN 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 157 CNLPGIKLSMPFISEKDESDI-RFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDmIQIFPKIENQEGFDNIREILEV 235
Cdd:PLN02461 179 VNLPGVVVDLPTLTEKDKEDIlQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKS-ILLISKVENQEGLDNFDDILAE 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 236 ADGVMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESA 315
Cdd:PLN02461 258 SDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETA 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 316 AGHYPVESVQTMTKIANAIEPMIPYKDRLKANVKSSKRTLN--DAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRP 393
Cdd:PLN02461 338 AGAYPELAVKTMARICREAEASLDYGALFKEIMRSAPLPMSplESLASSAVRTANKVKASLIVVLTRGGTTARLVAKYRP 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 394 CAPILAVTFDEVTQRSL-------------LPVNGVTPVVSNI------QNNKENDIDLARNLALQAGF-KTGDHiiVVA 453
Cdd:PLN02461 418 AVPILSVVVPEITTDSFdwscsdeaparhsLIYRGLIPVLAEGsakatdSESTEEILEAAIEHAKKKGLcKPGDS--VVA 495
|
490
....*....|....*..
gi 2088970467 454 GYPIgsGNTNMMRIAQI 470
Cdd:PLN02461 496 LHRI--GGASVIKILTV 510
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
29-467 |
6.49e-106 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 322.39 E-value: 6.49e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 29 MNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGGCNFVEGDEIDLVKDEVL---GNHERF 105
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTDPAFadkGTKDKF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 106 TLRCPEVFNDVKVGDYILMDDG--KMKVTFTEvTPDRIHGVVNNPHFLKSRKGCNLPGIKLSMPFISEKDESDIRFGCKM 183
Cdd:PTZ00300 81 YIDYQNLSKVVRPGGYIYIDDGilILHVQSHE-DEQTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 184 DVDYIAASFTRRKDDVLAIRQILIDENKDmIQIFPKIENQEGFDNIREILEVADGVMVARGDLGVDVSLELVPIYQKRMI 263
Cdd:PTZ00300 160 GVDMIFASFIRSAEQVGEVRKALGAKGGD-IMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 264 AAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYPVESVQTMTKIA----NAIEPMIP 339
Cdd:PTZ00300 239 SKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICleaqSAVNEYVF 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 340 YKDRLKanVKSSKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPILAVTFDEVTQRSLLPVNGVTPV 419
Cdd:PTZ00300 319 FNSIKK--LQPIPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESV 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 2088970467 420 VSNIQ-----NNKENDIDLARNLALQAGF-KTGDHIIVVAGYPIGSGNTNMMRI 467
Cdd:PTZ00300 397 FFDAErlghdEGKEQRVAMGVGFAKSKGYvQSGDLMVVVHADHKVKGYANQTRI 450
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
3-452 |
9.81e-100 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 310.71 E-value: 9.81e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 3 KKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKE-TGKPIGILLDTKGPEIRLGDFENG 81
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNAQsKDNVIAIMLDTKGPEVRSGDLPQP 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 82 gCNFVEGDEIDLVKDEVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNLPG 161
Cdd:PLN02623 190 -IMLEEGQEFTFTIKRGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNVRG 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 162 IKLSMPFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDmIQIFPKIENQEGFDNIREILEVADGVMV 241
Cdd:PLN02623 269 KSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNAD-IHVIVKIESADSIPNLHSIITASDGAMV 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 242 ARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYPV 321
Cdd:PLN02623 348 ARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPL 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 322 ESVQTMTKIANAIEPMIPYKDRLKANVKSSKRTLNDAIGISVADTALAIDIKcIIAFTQSGNTARRLAKFRPCAPILAVT 401
Cdd:PLN02623 428 KAVKVMHTVALRTEATLPEGTTPPNLGQAFKNHMSEMFAFHATMMANTLGTS-IIVFTRTGFMAILLSHYRPSGTIFAFT 506
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 2088970467 402 FDEVTQRSLLPVNGVTPVVSNIQNNKENDIDLARNLALQAGF-KTGDHIIVV 452
Cdd:PLN02623 507 NEKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMvKEGEEVALV 558
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
5-451 |
7.80e-91 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 285.80 E-value: 7.80e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 5 TKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGGCN 84
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEKPIS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 85 FVEGDEIDLVKDE-VLGNHERFTLRCPEVFNDVKVGDYILMddGKMKVTFTEVTP-----DRIHG-----VVNNphflks 153
Cdd:PLN02765 110 LKAGNTVTLTPDQsKEASSEVLPINFPGLAKAVKPGDTIFV--GQYLFTGSETTSvwlevDEVKGddvvcTVKN------ 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 154 rkGCNLPG---------IKLSMPFISEKDESDIR-FGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDMIQIFPKIENQ 223
Cdd:PLN02765 182 --SATLAGslftlhvsqVRIDLPTLSEKDKEVIStWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGLSQTQIFAKIENV 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 224 EGFDNIREILEVADGVMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITaTHMLESMQENPRPTRAEASDVANAIMD 303
Cdd:PLN02765 260 EGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLD 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 304 GTDCIMLSGESAAGHYPVESVQTMTKIANAIEPMIPYKDRLKANVKSSKRTLNDAigISVADTAL--AIDIKC--IIAFT 379
Cdd:PLN02765 339 GADAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKKTVKYVGEPMSHL--ESIASSAVraAIKVKAsvIIVFT 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 380 QSGNTARRLAKFRPCAPILAVTFDEVTQ-------------RSLLPVNGVTPVVSNIQNNKEND-------IDLARNLAL 439
Cdd:PLN02765 417 SSGRAARLIAKYRPTMPVLSVVIPRLKTnqlkwsftgafqaRQCLIVRGLFPMLADPRHSAESTsatnesvLKVALDHGK 496
|
490
....*....|...
gi 2088970467 440 QAGF-KTGDHIIV 451
Cdd:PLN02765 497 AAGViKSHDRVVV 509
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
8-335 |
1.02e-89 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 277.21 E-value: 1.02e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 8 ICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHaervKRIREVSKETGKPIGILLDTKGPEIRLGDFENGGCNFVE 87
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESH----KDIIRLVKSLDDSIKILGDVQGPKIRLGEIKGEQITLQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 88 GDEIDLVKDEVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPDRIHGVVNNPHFLKSRKGCNLPGIKLSMP 167
Cdd:PRK06739 82 GDSFILHTQPVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRLP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 168 FISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDENKDMIQIFPKIENQEGFDNIREILEVADGVMVARGDLG 247
Cdd:PRK06739 162 AITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPNLIAKIETMEAIENFQDICKEADGIMIARGDLG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 248 VDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYPVESVQTM 327
Cdd:PRK06739 242 VELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVSTL 321
|
....*...
gi 2088970467 328 TKIANAIE 335
Cdd:PRK06739 322 RLVSEFAE 329
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
2-453 |
1.23e-82 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 263.91 E-value: 1.23e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 2 SKKTKIICTIGPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFenG 81
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDL--G 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 82 GCNFV---EGDEIDLVKDEVLGNHERFTLRCP-EVF-NDVKVGDYILMDDGkMkVTFtEVtpdrIHGVVNNPHFLKSRKG 156
Cdd:PLN02762 102 GASSAkaeDGEEWTFTVRKFDGSRPEFTIQVNyDGFaEDVKVGDELVVDGG-M-VRF-EV----IEKIGPDVKCKCTDPG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 157 CNLPGIKLSM--------------PFISEKDESDIRFGCKMDVDYIAASFTRRKDDVLAIRQILIDEN-KDMIQIFPKIE 221
Cdd:PLN02762 175 LLLPRANLTFwrdgslvrernamlPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSrDSDIGVIAKIE 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 222 NQEGFDNIREILEVADGVMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHMLESMQENPRPTRAEASDVANAI 301
Cdd:PLN02762 255 SLDSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAV 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 302 MDGTDCIMLSGESAAGHYPVESVQTMTKIANAIEPMIPYKDRLKA-NVKSSKRTLNDAIGISVADTA------LAIDikC 374
Cdd:PLN02762 335 RQRADALMLSGESAMGLYPEKALSVLRSVSLRMELWSREEKRHEAlELPQLSSSLSDRISEEICNSAakmannLGVD--A 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 375 IIAFTQSGNTARRLAKFRPCAPILAVTFDEVTQRSLLPVNGVTPVVSNIQNNKENDIDLARNLALQAGF-KTGDHIIVVA 453
Cdd:PLN02762 413 IFVYTKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLDFSDDMESNLNKTFSLLKARGMiKSGDLVIAVS 492
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
266-467 |
9.97e-60 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 198.59 E-value: 9.97e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 266 ANEVGKPAITATHMLESMQENPRPTRAEASDVANAIMDGTDCIMLSGESAAGHYPVESVQTMTKIANAIEPMIPYKDRLK 345
Cdd:COG3848 2 CNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 346 ANVKSSKRTLNDAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPILAVTFDEVTQRSLLPVNGVTPVVSNIQN 425
Cdd:COG3848 82 PRAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEESA 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2088970467 426 NKENDIDLARNLALQAGF-KTGDHIIVVAGYPIG-SGNTNMMRI 467
Cdd:COG3848 162 STDEMFAVAVALALEAGLvKDGDLVVITAGVPVGvSGTTNLLKV 205
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
5-327 |
1.10e-43 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 160.18 E-value: 1.10e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 5 TKIICTI-GPASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDF--ENG 81
Cdd:PRK08187 135 TRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVagPLG 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 82 GCNFVEGDEIDLVK----DEVLGNHERFTLRCPEVFNDVKVGDYILMDDGKMKVTFTEVTPD----RIHGVVNNPHFLKS 153
Cdd:PRK08187 215 KTRLYTGDRLALVAqgppRRIDEEHFQVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGgallEVTHARPKGLKLKP 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 154 RKGCNLPGIKLSMPFISEKDESDIRFGCKmDVDYIAASFTRRKDDV------LAIRQiliDENKDMIQIFPKIENQEGFD 227
Cdd:PRK08187 295 EKGLNFPDTALDLPALTEKDRADLDFVAR-HADLVGYSFVQSPGDVealqaaLAARR---PDDWRKLGLVLKIETPRAVA 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 228 NIREILEVADG-----VMVARGDLGVDVSLELVPIYQKRM--IAAANEVgkPAITATHMLESMQENPRPTRAEASDVANA 300
Cdd:PRK08187 371 NLPELIVQAAGrqpfgVMIARGDLAVEIGFERLAEMQEEIlwLCEAAHV--PVIWATQVLEGLVKKGLPSRAEMTDAAMA 448
|
330 340
....*....|....*....|....*..
gi 2088970467 301 imDGTDCIMLSgesaAGHYPVESVQTM 327
Cdd:PRK08187 449 --ARAECVMLN----KGPYLVEAVTFL 469
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
357-467 |
9.46e-38 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 133.76 E-value: 9.46e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 357 DAIGISVADTALAIDIKCIIAFTQSGNTARRLAKFRPCAPILAVTFDEVTQRSLLPVNGVTPVVSNIQNNKENDIDLARN 436
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVK 80
|
90 100 110
....*....|....*....|....*....|...
gi 2088970467 437 LALQAGF-KTGDHIIVVAGYPIG-SGNTNMMRI 467
Cdd:pfam02887 81 VAKEAGLvKKGDLVVITAGVPFGvSGTTNTLKV 113
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
14-330 |
6.63e-37 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 143.17 E-value: 6.63e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 14 ASESKEVLTKLVEAGMNIARLNFSHGDYEEHAERVKRIREVSKETGKPIGILLDTKGPEIRLGDFENGG----------- 82
Cdd:PRK14725 151 AADDPDLVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGRRCRIAMDLAGPKLRTGPIAPGPrviklrptrda 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 83 ------------------------CNFV------------EGDEIDL--------------VKDEV-------------- 98
Cdd:PRK14725 231 lgrvltparlwltasespppspppGPVGlpvdpewlarlePGDELRFtdargkkrkltvteVDDEGvlaegsqtaylang 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 99 ----LGNHERFTLR---------------------------------------C--PEVFNDVKVGDYILMDDGKMKVTF 133
Cdd:PRK14725 311 tllrLGRHDSTRVGglppveqklrlkvgdrlvltrddapgdpaqgdapparisCtlPEAFRAARVGERVWFDDGKIGAVV 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 134 TEVTPDRIH--------GVVNnphfLKSRKGCNLPGIKLSMPFISEKDESDIRFGCKMdVDYIAASFTRRKDDVLAIRQI 205
Cdd:PRK14725 391 VKVEADEVElritharpGGSK----LKAGKGINLPDSHLPLPALTDKDLEDLAFVAKH-ADIVALSFVRSPEDVRLLLDA 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088970467 206 LIDENKDMIQIFPKIENQEGFDNIREILEVA-----DGVMVARGDLGVDVSLELVPIYQKRMIAAANEVGKPAITATHML 280
Cdd:PRK14725 466 LEKLGADDLGVVLKIETRRAFENLPRILLEAmrhprFGVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVL 545
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 2088970467 281 ESMQENPRPTRAEASDVANAIMdgTDCIMLSgesaAGHYPVESVQTMTKI 330
Cdd:PRK14725 546 ESLAKKGLPSRAEITDAAMALR--AECVMLN----KGPHIVEAVRVLDDI 589
|
|
| |
