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Conserved domains on  [gi|2090267596|ref|WP_222907980|]
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ABC transporter permease subunit, partial [Burkholderia arboris]

Protein Classification

ABC transporter permease( domain architecture ID 30)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TM_PBP2 super family cl00427
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 1-183 2.08e-80

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


The actual alignment was detected with superfamily member PRK10683:

Pssm-ID: 444901  Cd Length: 317  Bit Score: 241.54  E-value: 2.08e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596   1 VLMMAVMLPFWTSFLIRVYAWIGILKDDGLLNHTLIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLT 80
Cdd:PRK10683  134 ILLLLVILPSWTSFLIRVYAWMGILKNNGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYLPFMVLPIYTALTRIDYS 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  81 LLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGADTLMIGRVMWDEFFNNMDWPMASAVTVA 160
Cdd:PRK10683  214 LVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQEFFNNRDWPVASAVAII 293

                         170       180
                  ....*....|....*....|...
gi 2090267596 161 MVLLLLVPMALFQYYQVKELEEA 183
Cdd:PRK10683  294 MLLLLIVPIMWFHKHQQKSVGEH 316
 
Name Accession Description Interval E-value
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 1-183 2.08e-80

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 241.54  E-value: 2.08e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596   1 VLMMAVMLPFWTSFLIRVYAWIGILKDDGLLNHTLIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLT 80
Cdd:PRK10683  134 ILLLLVILPSWTSFLIRVYAWMGILKNNGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYLPFMVLPIYTALTRIDYS 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  81 LLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGADTLMIGRVMWDEFFNNMDWPMASAVTVA 160
Cdd:PRK10683  214 LVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQEFFNNRDWPVASAVAII 293

                         170       180
                  ....*....|....*....|...
gi 2090267596 161 MVLLLLVPMALFQYYQVKELEEA 183
Cdd:PRK10683  294 MLLLLIVPIMWFHKHQQKSVGEH 316
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-184 1.92e-79

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 237.74  E-value: 1.92e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596   1 VLMMAVMLPFWTSFLIRVYAWIGILKDDGLLNHTLIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLT 80
Cdd:COG1176   104 LLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEPLRLLYTEFAVVIGLVYVYLPFMVLPLYAALEKIDPS 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  81 LLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGADTLMIGRVMWDEFFNNMDWPMASAVTVA 160
Cdd:COG1176   184 LLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQFLSALNWPLAAALAVV 263

                         170       180
                  ....*....|....*....|....
gi 2090267596 161 MVLLLLVPMALFQYYQVKELEEAK 184
Cdd:COG1176   264 LLLIVLLVLLLYLRLLRRRRLLGG 287
modB_ABC TIGR02141
molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, ...
 52-138 1.84e-12

molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, of the molybdate ABC transporter. This system has been characterized in E. coli, Staphylococcus carnosus, Rhodobacter capsulatus and Azotobacter vinlandii. Molybdate is chemically similar to sulfate, thiosulfate, and selenate. These related substrates, and sometimes molybdate itself, can be transported by the homologous sulfate receptor. Some apparent molybdenum transport operons include a permease related to this ModB, although less similar than some sulfate permease proteins and not included in this model. [Transport and binding proteins, Anions]


Pssm-ID: 273993 [Multi-domain]  Cd Length: 208  Bit Score: 63.03  E-value: 1.84e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  52 AGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYvipellgG 131
Cdd:TIGR02141  81 TGAVLASVIVSFPLMVQPIRAAFEAVDPDLEEAARTLGASESQTFLKVTLPLAFPGLLAGAVLSFARALGEF-------G 153


                  ....*..
gi 2090267596 132 AdTLMIG 138
Cdd:TIGR02141 154 A-TLMFA 159
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 35-167 1.42e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.59  E-value: 1.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  35 LIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLL 114
Cdd:cd06261    57 VLLFGVLLGWGILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVL 136

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2090267596 115 VFIPAVGEYVIPELLGGADTLMIGRVMWDEFFNNMDWPMASAVTVAMVLLLLV 167
Cdd:cd06261   137 AFARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 35-174 1.44e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 49.22  E-value: 1.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  35 LIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLL 114
Cdd:pfam00528  36 AILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLAL 115

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2090267596 115 VFIPAVGEYVIPELLGGADTL--MIGRVMWDEFFNNMDWPMAsAVTVAMVLLLLVPMALFQY 174
Cdd:pfam00528 116 AFGGALGGAVLLEFLGSWPGLglLLIEAILGYDYPEIQGPVL-AAALILLLLNLLVDILQRL 176
 
Name Accession Description Interval E-value
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 1-183 2.08e-80

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 241.54  E-value: 2.08e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596   1 VLMMAVMLPFWTSFLIRVYAWIGILKDDGLLNHTLIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLT 80
Cdd:PRK10683  134 ILLLLVILPSWTSFLIRVYAWMGILKNNGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYLPFMVLPIYTALTRIDYS 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  81 LLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGADTLMIGRVMWDEFFNNMDWPMASAVTVA 160
Cdd:PRK10683  214 LVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQEFFNNRDWPVASAVAII 293

                         170       180
                  ....*....|....*....|...
gi 2090267596 161 MVLLLLVPMALFQYYQVKELEEA 183
Cdd:PRK10683  294 MLLLLIVPIMWFHKHQQKSVGEH 316
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-184 1.92e-79

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 237.74  E-value: 1.92e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596   1 VLMMAVMLPFWTSFLIRVYAWIGILKDDGLLNHTLIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLT 80
Cdd:COG1176   104 LLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEPLRLLYTEFAVVIGLVYVYLPFMVLPLYAALEKIDPS 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  81 LLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGADTLMIGRVMWDEFFNNMDWPMASAVTVA 160
Cdd:COG1176   184 LLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQFLSALNWPLAAALAVV 263

                         170       180
                  ....*....|....*....|....
gi 2090267596 161 MVLLLLVPMALFQYYQVKELEEAK 184
Cdd:COG1176   264 LLLIVLLVLLLYLRLLRRRRLLGG 287
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 2-180 2.58e-48

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 158.31  E-value: 2.58e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596   2 LMMAVMLPFWTSFLIRVYAWIGILKDDGLLNHTLIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTL 81
Cdd:PRK09497  101 LLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTESAVIIGLVYILLPFMVLPLYSSIEKLDKPL 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  82 LEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGADTLMIGRVMWDEFFNNMDWPMASAVTVAm 161
Cdd:PRK09497  181 LEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIKSQFLNIRDWPFGAATSIT- 259

                         170
                  ....*....|....*....
gi 2090267596 162 vLLLLVPMALFQYYQVKEL 180
Cdd:PRK09497  260 -LTIVMGLMLLVYYRASKL 277
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 63-176 1.84e-21

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 87.86  E-value: 1.84e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  63 LPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGADTLMIGRVMW 142
Cdd:COG1177   143 LPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGVTTLPVYIY 222

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2090267596 143 DEFFNNMDwPMASAVTVAMVLLLLVPMALFQYYQ 176
Cdd:COG1177   223 SMIRRGIS-PEINALSTLLILLSLLLLLLAERLR 255
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
1-176 7.12e-20

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 85.98  E-value: 7.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596   1 VLMMAVMLPFWTSFLIRVYAWIGILKDDGLLNHTLIALGIIHTPlRLYhSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLT 80
Cdd:COG1178    91 LLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRALFGLEPP-DIY-GLGGIILVLVLFNYPYVYLLLRAALRSIDAS 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  81 LLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGADTlMIGRVMWDEFFNNMDWPMASAVTVA 160
Cdd:COG1178   169 LEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVLGGGYT-TLTTAIYQAWLGDFDLGAAAALALV 247

                         170
                  ....*....|....*.
gi 2090267596 161 MVLLLLVPMALFQYYQ 176
Cdd:COG1178   248 LLLLVLLLLLLERRLR 263
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
34-172 5.23e-16

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 74.81  E-value: 5.23e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  34 TLIALGII-----HTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGI 108
Cdd:COG1178   389 IVLGLGLLllfnrPLPLLLYGTLAILVLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGL 468

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2090267596 109 IAGSLLVFIPAVGEYVIPELLGGADTLMIGRVMWdEFFNNMDWPMASAVTVAMVLLLLVPMALF 172
Cdd:COG1178   469 LAAALLVFVTSMKELSATLLLRPPGFETLAVLIY-QLASSGRYGEAAALALLLVLVSLLPVLLL 531
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 52-138 1.86e-15

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 71.23  E-value: 1.86e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  52 AGVYIG-MVYSyLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYvipellg 130
Cdd:COG4149    91 TGAVLAsVVVS-LPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLAFARALGEF------- 162


                  ....*...
gi 2090267596 131 GAdTLMIG 138
Cdd:COG4149   163 GA-TLMFA 169
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 29-176 1.66e-14

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 69.39  E-value: 1.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  29 GLLNHTLIALGI--IHTPLrlyhsdaGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKN 106
Cdd:COG0555   119 GWLGQLLAPLGIkvAFTPL-------GIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLP 191

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2090267596 107 GIIAGSLLVFIPAVGEY--VIpeLLGGAdTLMIGRVMWDEFFNNM---DWPMASAVTVAMVLLLLVPMALFQYYQ 176
Cdd:COG0555   192 ALLTGFALAFARALGEFgaVI--FIAGN-LPMKTEILPLLIYLKLeegDYAGATAIALVLLLISFLLLLLINLLQ 263
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 13-177 3.41e-13

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 66.18  E-value: 3.41e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  13 SFLIRVyAWIGILKDDGLLNHTLIALGIIHT-PLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAK 91
Cdd:PRK15050  123 SFLITL-AFTFLYGSAGSVNIALQRLFGLEApPLDFLYSPGGVILAEITFYTPFVVRPLLAAFAQLDARQLEAAASLGAS 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  92 PWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGADTLMIGRVMWDEFFNNMDWPMASAVTVAMVLLLLvpmAL 171
Cdd:PRK15050  202 PWRVARRVILPEAWPALAAGGSLCLLLTLNEFGIVLFTGAKDVVTLPVLIYSKAIVDFDYPTACAIAVVNLALSL---GL 278


                  ....*.
gi 2090267596 172 FQYYQV 177
Cdd:PRK15050  279 YALYRR 284
modB_ABC TIGR02141
molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, ...
 52-138 1.84e-12

molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, of the molybdate ABC transporter. This system has been characterized in E. coli, Staphylococcus carnosus, Rhodobacter capsulatus and Azotobacter vinlandii. Molybdate is chemically similar to sulfate, thiosulfate, and selenate. These related substrates, and sometimes molybdate itself, can be transported by the homologous sulfate receptor. Some apparent molybdenum transport operons include a permease related to this ModB, although less similar than some sulfate permease proteins and not included in this model. [Transport and binding proteins, Anions]


Pssm-ID: 273993 [Multi-domain]  Cd Length: 208  Bit Score: 63.03  E-value: 1.84e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  52 AGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYvipellgG 131
Cdd:TIGR02141  81 TGAVLASVIVSFPLMVQPIRAAFEAVDPDLEEAARTLGASESQTFLKVTLPLAFPGLLAGAVLSFARALGEF-------G 153


                  ....*..
gi 2090267596 132 AdTLMIG 138
Cdd:TIGR02141 154 A-TLMFA 159
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
1-179 6.85e-11

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 59.38  E-value: 6.85e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596   1 VLMMAVMLPFWTSFLIRVYAWIGILKDD-GLLNHTLIALGIiHTPLRLYHSD---AGVYIGMVYSYLPFMVMPLYAHLVK 76
Cdd:COG1175   112 FFRTLFFLPWVISPVVVALIWKWLFNPDyGLLNALLGALGL-EPINWLGDPSlalPAVIIVTVWKGTGFNMLIFLAGLQS 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  77 MDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELL--GGAD--TLMIGRVMWDEFFNNMDWP 152
Cdd:COG1175   191 IPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLtgGGPGnsTTTLVLYIYQTAFQQFDFG 270

                         170       180
                  ....*....|....*....|....*..
gi 2090267596 153 MASAVTVAMVLLLLVPMALFQYYQVKE 179
Cdd:COG1175   271 YASAIAVVLFLIILVLTLLQLRLLRRR 297
cysT CHL00187
sulfate transport protein; Provisional
 5-123 3.99e-10

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 56.95  E-value: 3.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596   5 AVMLPFWTSFLIRVYAWIGILKDDGLLNHTLIALGIihtplRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEA 84
Cdd:CHL00187   96 AVDLPFALPTSVAGLTLATVYGDNGWIGHLLSHLGI-----QIVFTKLGVLLAMIFVSFPFVVRTIQPVLQEIEKELEEA 170

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2090267596  85 AYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEY 123
Cdd:CHL00187  171 AWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGEY 209
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 35-167 1.42e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.59  E-value: 1.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  35 LIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLL 114
Cdd:cd06261    57 VLLFGVLLGWGILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVL 136

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2090267596 115 VFIPAVGEYVIPELLGGADTLMIGRVMWDEFFNNMDWPMASAVTVAMVLLLLV 167
Cdd:cd06261   137 AFARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
modB PRK09421
molybdate ABC transporter permease subunit;
63-123 8.19e-09

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 53.00  E-value: 8.19e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2090267596  63 LPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEY 123
Cdd:PRK09421  104 FPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLGEF 164
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 53-131 1.87e-08

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 52.76  E-value: 1.87e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2090267596  53 GVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGG 131
Cdd:TIGR03262 135 GIVIGEVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGG 213
Mo_ABC_porter TIGR01581
NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively ...
 29-167 3.44e-08

NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively weak homology compared to its neighbor clades, the molybdate (TIGR02141) and sulfate (TIGR00969) porters. Neighbor-Joining, PAM-distance phylogenetic trees support the separation of the clades in this way. Included in this group is a gene designated NifC in Clostridium pasturianum. It would be reasonable to presume that NifC acts as a molybdate porter since the most common form of nitrogenase is a molybdoenzyme. Several other sequences falling within the scope of this model are annotated as molybdate porters and one, from Halobacterium, is annotated as a sulfate porter. There is presently no experimental evidence to support annotations with this degree of specificity.


Pssm-ID: 130643  Cd Length: 225  Bit Score: 51.24  E-value: 3.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  29 GLLNHTLIALGIihtplRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGI 108
Cdd:TIGR01581  86 GLLGPYLEAAGI-----QVIFSTLGVVLAQTFVASPYYVRVARSTFKSVDPRYEDVARSLGAGPLETFRKITLPMARPGL 160

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2090267596 109 IAGSLLVFIPAVGEYVIPELLGGAdTLMIGRVMWDEFFNNMDWPMASAVTVAMVLLLLV 167
Cdd:TIGR01581 161 LAGLVLAWARALGEFGATLMFAGS-IQGKTRTLPLAIYLNIQSDNIEAAVASALLLLVI 218
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 63-116 3.59e-08

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 51.52  E-value: 3.59e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2090267596  63 LPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVF 116
Cdd:PRK09500  139 LPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSF 192
3a0106s02 TIGR00969
sulfate ABC transporter, permease protein; This model describes a subfamily of both CysT and ...
 53-173 1.19e-07

sulfate ABC transporter, permease protein; This model describes a subfamily of both CysT and CysW, paralogous and generally tandemly encoded permease proteins of the sulfate ABC transporter. [Transport and binding proteins, Anions]


Pssm-ID: 273370  Cd Length: 271  Bit Score: 50.04  E-value: 1.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  53 GVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEY----VIPEL 128
Cdd:TIGR00969 144 GMALAMIFVSLPFVVREVQPVLEELGTEAEEAAATLGASGWQTFWRVTLPSIRWALLYGVVLTFARALGEFgavvVVSGN 223

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2090267596 129 LGGADtlMIGRVMWDEFFNNMDWPMAS---AVTVAMVLLLLVPMALFQ 173
Cdd:TIGR00969 224 IPGKT--LTLPLLIEERLEQYDYPGAYviaAVLLLVSLVTLFLINALQ 269
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 35-174 1.44e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 49.22  E-value: 1.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  35 LIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLL 114
Cdd:pfam00528  36 AILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLAL 115

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2090267596 115 VFIPAVGEYVIPELLGGADTL--MIGRVMWDEFFNNMDWPMAsAVTVAMVLLLLVPMALFQY 174
Cdd:pfam00528 116 AFGGALGGAVLLEFLGSWPGLglLLIEAILGYDYPEIQGPVL-AAALILLLLNLLVDILQRL 176
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 83-176 1.04e-06

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 47.45  E-value: 1.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  83 EAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGAD---TLMIGRVMWDEFFNNMDWPM--ASAV 157
Cdd:COG3833   175 EAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPenyTLAVGLYSFVSDQRNTNWGVfaAGAV 254

                          90       100
                  ....*....|....*....|
gi 2090267596 158 TVAmvllllVP-MALFQYYQ 176
Cdd:COG3833   255 LVA------IPiVILFLFLQ 268
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
53-173 2.17e-06

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 46.67  E-value: 2.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  53 GVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYvipellgGA 132
Cdd:PRK10971  142 GIAVAMAFTSIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEF-------GA 214

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2090267596 133 DTLMIGRVMW-DEFFNNM--------DWPMASA---VTVAMVLLLLVPMALFQ 173
Cdd:PRK10971  215 VIFIAGNIAWkTEVTSLMifvrlqefDYPAASAiasVILAASLLLLFSINTLQ 267
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 34-173 2.86e-05

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 43.16  E-value: 2.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  34 TLIALGIIHTPLRLYHSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSL 113
Cdd:COG0395   127 LLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAI 206

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2090267596 114 LVFIPAVGEYVIPELLGGAD---TLMIG-RVMWDEFfnNMDWPMASAVTVAMVLLLLVPMALFQ 173
Cdd:COG0395   207 FTFIGAWNDFLWPLILLTSPdlrTLPVGlASFQGQY--GTDWGLLMAAAVIATLPVLILFLFLQ 268
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 83-131 2.02e-03

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 37.63  E-value: 2.02e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2090267596  83 EAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGG 131
Cdd:TIGR02138 183 EASYALGATKWETIRRVILPAARSGIVGAVVLGLGRALGETMAVTMVIG 231
COG4132 COG4132
ABC-type uncharacterized transport system, permease component [General function prediction ...
 19-178 2.85e-03

ABC-type uncharacterized transport system, permease component [General function prediction only];


Pssm-ID: 443307 [Multi-domain]  Cd Length: 286  Bit Score: 37.48  E-value: 2.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  19 YAWIGILKDDGLLNHTLIALGI-IHTPLRLYhSDAGVYIGMVYSYLPFMVMPLYAHLVKMDLTLLEAAYDLGAKPWVAFT 97
Cdd:COG4132   119 FAFIATLGRNGLVTLLLKQLGIdLYDGFNLY-SFWGLILVYLYFQIPLMVLLLYPALDGLRREWREAAALLGASRWQYWR 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  98 RITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGGAD----TLMIGRVMWDEFFNNMDwpMASAVTVAMVLLLLVPMALFQ 173
Cdd:COG4132   198 RVALPVLAPSLLGTFLLLFANAFGAYATAYALTGGNynlvPIRIGALISGDVLLDPN--LGAALALGMIVIMALVMALYQ 275


                  ....*
gi 2090267596 174 YYQVK 178
Cdd:COG4132   276 WLQRR 280
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 81-122 4.47e-03

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 36.61  E-value: 4.47e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2090267596  81 LLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGE 122
Cdd:COG0573   186 LREAALALGATRWETIRKVVLPAARSGIIAAVILGLGRALGE 227
PRK10592 PRK10592
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 72-131 4.79e-03

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182574  Cd Length: 281  Bit Score: 36.75  E-value: 4.79e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2090267596  72 AHLVKMDLTLLEAAYDLGAKPWVAFTRITLPLSKNGIIAGSLLVFIPAVGEYVIPELLGG 131
Cdd:PRK10592  161 SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFVSG 220
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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