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Conserved domains on  [gi|2096805200|ref|WP_223257626|]
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MULTISPECIES: site-specific DNA recombinase SpoIVCA [Bacillus]

Protein Classification

recombinase family protein( domain architecture ID 11449350)

recombinase family protein is a serine recombinase that catalyzes the site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SpoIVCA COG1961
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ...
2-338 7.86e-51

Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair];


:

Pssm-ID: 441564 [Multi-domain]  Cd Length: 388  Bit Score: 177.52  E-value: 7.86e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200   2 KGSSIDSQIEAC---IKKAGTKDVLKYADEGFSGELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDELR 78
Cdd:COG1961    16 EGLSLERQREALrayAEKAGWEIVRIYVDEGVSGTSKDRPGLQRLLADLRAGKFDTLVVWKLDRLGRNLADLLELVEELK 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200  79 KRNIPLIFVNGEYA-NSPEGQLFFAMRGAISEFEKAKIKERTSSGRLQKMKKGMIIKdSKLYGYkfvKEKRTLEILEEEA 157
Cdd:COG1961    96 ERGVRLISLTEGIDtSTPMGRLLLTILAAFAEFERELISERTRAGLAAAKARGKYLG-RPPYGY---RDPKKLVIDEEEA 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200 158 KIIRMIFNYFTDHKSpffgrVNGIALHLTQMGVKTkkgakvWHRQVVRQILMNSSYKGE--HRQYKYDTEGSYVSKQAGN 235
Cdd:COG1961   172 EVVRRIFELYLEGKS-----LREIARELNERGIPT------WSRSTVYRILKNPVYGGLgvYGLGKKIVTEKGERKVRRR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200 236 KSIIKIRPEEEQITVTIPAIVPAEQWDYAQELLGQSKRKHLSISPHNYLLSGLVRCGKCGNTMTGKKRKSHGKDYYVYTC 315
Cdd:COG1961   241 RKRRVIREEEERVRRRELAAKRARRLLKGKLLRGLRGRKKRGGGRKRRRGGGRRLCGRLGRLRKGGRLRRCRLGRRLKAS 320
                         330       340
                  ....*....|....*....|...
gi 2096805200 316 RKNYSGAKDRGCGKEMSENKLNR 338
Cdd:COG1961   321 ARKLARGKLKEALLLEVLLELLE 343
 
Name Accession Description Interval E-value
SpoIVCA COG1961
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ...
2-338 7.86e-51

Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair];


Pssm-ID: 441564 [Multi-domain]  Cd Length: 388  Bit Score: 177.52  E-value: 7.86e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200   2 KGSSIDSQIEAC---IKKAGTKDVLKYADEGFSGELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDELR 78
Cdd:COG1961    16 EGLSLERQREALrayAEKAGWEIVRIYVDEGVSGTSKDRPGLQRLLADLRAGKFDTLVVWKLDRLGRNLADLLELVEELK 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200  79 KRNIPLIFVNGEYA-NSPEGQLFFAMRGAISEFEKAKIKERTSSGRLQKMKKGMIIKdSKLYGYkfvKEKRTLEILEEEA 157
Cdd:COG1961    96 ERGVRLISLTEGIDtSTPMGRLLLTILAAFAEFERELISERTRAGLAAAKARGKYLG-RPPYGY---RDPKKLVIDEEEA 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200 158 KIIRMIFNYFTDHKSpffgrVNGIALHLTQMGVKTkkgakvWHRQVVRQILMNSSYKGE--HRQYKYDTEGSYVSKQAGN 235
Cdd:COG1961   172 EVVRRIFELYLEGKS-----LREIARELNERGIPT------WSRSTVYRILKNPVYGGLgvYGLGKKIVTEKGERKVRRR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200 236 KSIIKIRPEEEQITVTIPAIVPAEQWDYAQELLGQSKRKHLSISPHNYLLSGLVRCGKCGNTMTGKKRKSHGKDYYVYTC 315
Cdd:COG1961   241 RKRRVIREEEERVRRRELAAKRARRLLKGKLLRGLRGRKKRGGGRKRRRGGGRRLCGRLGRLRKGGRLRRCRLGRRLKAS 320
                         330       340
                  ....*....|....*....|...
gi 2096805200 316 RKNYSGAKDRGCGKEMSENKLNR 338
Cdd:COG1961   321 ARKLARGKLKEALLLEVLLELLE 343
Resolvase pfam00239
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ...
1-130 3.49e-35

Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.


Pssm-ID: 425548 [Multi-domain]  Cd Length: 144  Bit Score: 128.16  E-value: 3.49e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200   1 MKGSSIDSQIEACIKKAGTK-DVLKYADEGFSGELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDELRK 79
Cdd:pfam00239  11 DQDDSLERQLEALRAYAACNgKIVEFEDKGVSGRKLDRPGLQRLLALLRAGKGDVLVVYKLDRLGRSLRDLLTLVEELRE 90
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2096805200  80 RNIPLIFVNGEYANS-PEGQLFFAMRGAISEFEKAKIKERTSSGRLQKMKKG 130
Cdd:pfam00239  91 KGVDLVSLDEGIDTStPMGRLLLTILAALAEFERALIRERTRAGLAAAAARG 142
Resolvase smart00857
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ...
2-130 2.41e-30

Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.


Pssm-ID: 214861 [Multi-domain]  Cd Length: 148  Bit Score: 115.03  E-value: 2.41e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200    2 KGSSIDSQIEAC---IKKAGTKDVLKYADEGFSGELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDELR 78
Cdd:smart00857  13 ADGSLERQLEALrayAERNGWEVVRIYEDEGVSGKKADRPGLQRLLADLRAGDIDVLVVYKLDRLGRSLRDLLALLELLE 92
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2096805200   79 KRNIPLIFVNGEYAN--SPEGQLFFAMRGAISEFEKAKIKERTSSGRLQKMKKG 130
Cdd:smart00857  93 EKGVRLVSLKEGILDtsTPAGRLLLDILAALAEFERELISERTKAGLARAAARG 146
Ser_Recombinase cd00338
Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or ...
2-122 1.15e-28

Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.


Pssm-ID: 238206 [Multi-domain]  Cd Length: 137  Bit Score: 110.04  E-value: 1.15e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200   2 KGSSIDSQIEAC---IKKAGTKDVLKYADEGFSG-ELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDEL 77
Cdd:cd00338    12 QGDSLERQREALreyAARNGLEVVGEYEDAGSSAtSLVDRPGLQRLLADVKAGKIDVVLVEKLDRLSRNLVDLLELLELL 91
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2096805200  78 RKRNIPLIFVNGEYA-NSPEGQLFFAMRGAISEFEKAKIKERTSSG 122
Cdd:cd00338    92 EAHGVRVVTADGEIDlDSEDGRLMLGILAAMAEEESKLISERTKRG 137
 
Name Accession Description Interval E-value
SpoIVCA COG1961
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ...
2-338 7.86e-51

Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair];


Pssm-ID: 441564 [Multi-domain]  Cd Length: 388  Bit Score: 177.52  E-value: 7.86e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200   2 KGSSIDSQIEAC---IKKAGTKDVLKYADEGFSGELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDELR 78
Cdd:COG1961    16 EGLSLERQREALrayAEKAGWEIVRIYVDEGVSGTSKDRPGLQRLLADLRAGKFDTLVVWKLDRLGRNLADLLELVEELK 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200  79 KRNIPLIFVNGEYA-NSPEGQLFFAMRGAISEFEKAKIKERTSSGRLQKMKKGMIIKdSKLYGYkfvKEKRTLEILEEEA 157
Cdd:COG1961    96 ERGVRLISLTEGIDtSTPMGRLLLTILAAFAEFERELISERTRAGLAAAKARGKYLG-RPPYGY---RDPKKLVIDEEEA 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200 158 KIIRMIFNYFTDHKSpffgrVNGIALHLTQMGVKTkkgakvWHRQVVRQILMNSSYKGE--HRQYKYDTEGSYVSKQAGN 235
Cdd:COG1961   172 EVVRRIFELYLEGKS-----LREIARELNERGIPT------WSRSTVYRILKNPVYGGLgvYGLGKKIVTEKGERKVRRR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200 236 KSIIKIRPEEEQITVTIPAIVPAEQWDYAQELLGQSKRKHLSISPHNYLLSGLVRCGKCGNTMTGKKRKSHGKDYYVYTC 315
Cdd:COG1961   241 RKRRVIREEEERVRRRELAAKRARRLLKGKLLRGLRGRKKRGGGRKRRRGGGRRLCGRLGRLRKGGRLRRCRLGRRLKAS 320
                         330       340
                  ....*....|....*....|...
gi 2096805200 316 RKNYSGAKDRGCGKEMSENKLNR 338
Cdd:COG1961   321 ARKLARGKLKEALLLEVLLELLE 343
Resolvase pfam00239
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ...
1-130 3.49e-35

Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.


Pssm-ID: 425548 [Multi-domain]  Cd Length: 144  Bit Score: 128.16  E-value: 3.49e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200   1 MKGSSIDSQIEACIKKAGTK-DVLKYADEGFSGELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDELRK 79
Cdd:pfam00239  11 DQDDSLERQLEALRAYAACNgKIVEFEDKGVSGRKLDRPGLQRLLALLRAGKGDVLVVYKLDRLGRSLRDLLTLVEELRE 90
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2096805200  80 RNIPLIFVNGEYANS-PEGQLFFAMRGAISEFEKAKIKERTSSGRLQKMKKG 130
Cdd:pfam00239  91 KGVDLVSLDEGIDTStPMGRLLLTILAALAEFERALIRERTRAGLAAAAARG 142
Resolvase smart00857
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ...
2-130 2.41e-30

Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.


Pssm-ID: 214861 [Multi-domain]  Cd Length: 148  Bit Score: 115.03  E-value: 2.41e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200    2 KGSSIDSQIEAC---IKKAGTKDVLKYADEGFSGELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDELR 78
Cdd:smart00857  13 ADGSLERQLEALrayAERNGWEVVRIYEDEGVSGKKADRPGLQRLLADLRAGDIDVLVVYKLDRLGRSLRDLLALLELLE 92
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2096805200   79 KRNIPLIFVNGEYAN--SPEGQLFFAMRGAISEFEKAKIKERTSSGRLQKMKKG 130
Cdd:smart00857  93 EKGVRLVSLKEGILDtsTPAGRLLLDILAALAEFERELISERTKAGLARAAARG 146
Ser_Recombinase cd00338
Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or ...
2-122 1.15e-28

Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.


Pssm-ID: 238206 [Multi-domain]  Cd Length: 137  Bit Score: 110.04  E-value: 1.15e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200   2 KGSSIDSQIEAC---IKKAGTKDVLKYADEGFSG-ELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDEL 77
Cdd:cd00338    12 QGDSLERQREALreyAARNGLEVVGEYEDAGSSAtSLVDRPGLQRLLADVKAGKIDVVLVEKLDRLSRNLVDLLELLELL 91
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2096805200  78 RKRNIPLIFVNGEYA-NSPEGQLFFAMRGAISEFEKAKIKERTSSG 122
Cdd:cd00338    92 EAHGVRVVTADGEIDlDSEDGRLMLGILAAMAEEESKLISERTKRG 137
SR_ResInv cd03768
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ...
5-122 2.96e-18

Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.


Pssm-ID: 239737 [Multi-domain]  Cd Length: 126  Bit Score: 80.60  E-value: 2.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200   5 SIDSQIEAcIKKAGTKDVLkYADEGFSGELlERPALNRLREDASKGLIsqVICYDPDRLSRKLMNQLIIDDELRKRNIPL 84
Cdd:cd03768    13 SLERQLEA-LKAAGECDKI-FEEKGSGGKK-ERPELQKLLEDLREGDT--LVVTKLDRLGRSTKDLLEIVEELREKGVSL 87
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2096805200  85 IFVNGEYA-NSPEGQLFFAMRGAISEFEKAKIKERTSSG 122
Cdd:cd03768    88 RSLTEGIDtSTPSGKLMLTILGAFAEFERELIRERTKEG 126
Recombinase pfam07508
Recombinase; This domain is usually found associated with pfam00239 in putative integrases ...
154-268 2.65e-12

Recombinase; This domain is usually found associated with pfam00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages.


Pssm-ID: 429502 [Multi-domain]  Cd Length: 102  Bit Score: 62.80  E-value: 2.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200 154 EEEAKIIRMIFNYFTDHKSpffgrVNGIALHLTQMGVKTKKGAKvWHRQVVRQILMNSSYKGEHRQykydtegsyvSKQA 233
Cdd:pfam07508   1 PEEAEIVRLIFELYLEGKS-----LRSIARYLNEQGIPTPRGKD-WSPSTVRRILTNPAYIGILVY----------GKTK 64
                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2096805200 234 GNKSIIKIRPEEEQITVTIPAIVPAEQWDYAQELL 268
Cdd:pfam07508  65 KKRRKRNPDEEWIVIEGAHPPIISEELFEAVQERL 99
Zn_ribbon_recom pfam13408
Recombinase zinc beta ribbon domain; This short bacterial protein contains a zinc ribbon ...
284-344 5.64e-10

Recombinase zinc beta ribbon domain; This short bacterial protein contains a zinc ribbon domain that is likely to be DNA-binding. This domain is found in site specific recombinase proteins. This family appears most closely related to pfam04606.


Pssm-ID: 433183 [Multi-domain]  Cd Length: 58  Bit Score: 54.94  E-value: 5.64e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2096805200 284 LLSGLVRCGKCGNTMTGKKRKshgKDYYVYTCRKNYSGAKdrGCG-KEMSENKLNRHVWGEI 344
Cdd:pfam13408   1 LLSGLLRCGECGSPMTGRTSK---GGKRYYRCSTRRRKGK--KCSnHSIREEELEEAVLEAL 57
SR_TndX_transposase cd03770
Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of ...
4-89 2.35e-07

Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. TndX mediates the excision and circularization of the conjugative transposon Tn5397 from Clostridium difficile. TnpX is responsible for the movement of the nonconjugative chloramphenicol resistance elements of the Tn4451/3 family. Mobile genetic elements such as transposons are important vehicles for the transmission of virulence and antibiotic resistance in many microorganisms.


Pssm-ID: 239739 [Multi-domain]  Cd Length: 140  Bit Score: 50.06  E-value: 2.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096805200   4 SSIDSQ---IEACIKKAGTKDVLKYADEGFSGELLERPALNRLREDASKGLISQVICYDPDRLSR-KLMNQLIIDDELRK 79
Cdd:cd03770    18 NSIENQkaiLEEYAKENGLENIRHYIDDGFSGTTFDRPGFNRMIEDIEAGKIDIVIVKDMSRLGRnYLKVGLYMEILFPK 97
                          90
                  ....*....|
gi 2096805200  80 RNIPLIFVNG 89
Cdd:cd03770    98 KGVRFIAIND 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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