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Conserved domains on  [gi|2105040256|ref|WP_224992149|]
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MULTISPECIES: choline BCCT transporter BetT [Acinetobacter]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
3-509 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 680.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256   3 SKQPGWFANVNPNVFFGTVIIIALFLAVVVIAPSSFELLTQQLKQWITDSFSWFYVLSVAFFLILLIYIACSSIGRIKLG 82
Cdd:COG1292     4 KNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  83 PDHSQPEYNNGSWFAMLFTAGMGIGLMFFGVAEPVMHYVNPPSG-DAQTIDAAQQALRVTFFHWGLHAWAIYAVVGLALA 161
Cdd:COG1292    84 GDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALA 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 162 YFAYRHNLPLKTRSALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFGVTQINSGLHYLFGVEQSTHIQVLLIIFVS 241
Cdd:COG1292   164 YFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVIT 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 242 ILASLSVFLGLDKGVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTGQYISNLFTMTFNLYAYQPNGWIGGWTILY 321
Cdd:COG1292   244 ALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGDTGWLGGWTVFY 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 322 WAWWISWSPFVGMFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAALFSIIHEhQTTLIQAVQQDSSVALFEFLGH 401
Cdd:COG1292   324 WAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNG-GGDLAEAVAAGVEAALFALLEQ 402
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 402 LPWSGVMNILATILVVLFFVTSADSGALVTDYLTAK-TENSPTWQRLFWTVLMAVLAIILLLVGGLAALQSSIIMSALPF 480
Cdd:COG1292   403 LPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGgDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALPF 482
                         490       500
                  ....*....|....*....|....*....
gi 2105040256 481 TVVMLLMSWGLIKALHLDVTKMTAIQEAR 509
Cdd:COG1292   483 SFVLLLMCVSLVKALREDPRRLRSAEAEA 511
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
3-509 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 680.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256   3 SKQPGWFANVNPNVFFGTVIIIALFLAVVVIAPSSFELLTQQLKQWITDSFSWFYVLSVAFFLILLIYIACSSIGRIKLG 82
Cdd:COG1292     4 KNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  83 PDHSQPEYNNGSWFAMLFTAGMGIGLMFFGVAEPVMHYVNPPSG-DAQTIDAAQQALRVTFFHWGLHAWAIYAVVGLALA 161
Cdd:COG1292    84 GDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALA 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 162 YFAYRHNLPLKTRSALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFGVTQINSGLHYLFGVEQSTHIQVLLIIFVS 241
Cdd:COG1292   164 YFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVIT 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 242 ILASLSVFLGLDKGVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTGQYISNLFTMTFNLYAYQPNGWIGGWTILY 321
Cdd:COG1292   244 ALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGDTGWLGGWTVFY 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 322 WAWWISWSPFVGMFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAALFSIIHEhQTTLIQAVQQDSSVALFEFLGH 401
Cdd:COG1292   324 WAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNG-GGDLAEAVAAGVEAALFALLEQ 402
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 402 LPWSGVMNILATILVVLFFVTSADSGALVTDYLTAK-TENSPTWQRLFWTVLMAVLAIILLLVGGLAALQSSIIMSALPF 480
Cdd:COG1292   403 LPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGgDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALPF 482
                         490       500
                  ....*....|....*....|....*....
gi 2105040256 481 TVVMLLMSWGLIKALHLDVTKMTAIQEAR 509
Cdd:COG1292   483 SFVLLLMCVSLVKALREDPRRLRSAEAEA 511
PRK09928 PRK09928
choline transport protein BetT; Provisional
12-654 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 639.05  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  12 VNPNVFFGTVIIIALFLAVVVIAPSSFELLTQQLKQWITDSFSWFYVLSVAFFLILLIYIACSSIGRIKLGPDHSQPEYN 91
Cdd:PRK09928   15 INPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQSKPEFS 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  92 NGSWFAMLFTAGMGIGLMFFGVAEPVMHYVNPPSGDAQTIDAAQQALRVTFFHWGLHAWAIYAVVGLALAYFAYRHNLPL 171
Cdd:PRK09928   95 LLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPL 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 172 KTRSALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFGVTQINSGLHYLFGVEQSTHIQVLLIIFVSILASLSVFLG 251
Cdd:PRK09928  175 TIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSVIIATISVTSG 254
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 252 LDKGVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTGQYISNLFTMTFNLYAY-QPNGWIGGWTILYWAWWISWSP 330
Cdd:PRK09928  255 VNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFdRPTEWMNNWTLFFWAWWVAWSP 334
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 331 FVGMFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAALFSIIHEHQtTLIQAVQQDSSVALFEFLGHLPWSGVMNI 410
Cdd:PRK09928  335 FVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNA-AFAEEAMAHPERGFYSLLAQYPAFTFSAS 413
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 411 LATILVVLFFVTSADSGALVTDYLTAKTEN----SPTWQRLFWTVLMAVLAIILLLVGGLAALQSSIIMSALPFTVVMLL 486
Cdd:PRK09928  414 VATITGLLFYVTSADSGALVLGNFTSKLKDinsdAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFF 493
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 487 MSWGLIKALHL-DVTKMTAIQEARITPRAIHNPRSWQQRLGLIMHYPHSeEEVREYIEKQVSRAFENIKHEFRRRHLEVS 565
Cdd:PRK09928  494 VMAGLYKSLKVeDYRRASANRDTAPRLVGLQDRLNWKQRLSRVMNYPGT-RYTRRMLDTVCRPAMEEVAQELRLRGAYVE 572
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 566 ITQLEDG-------MQLRVDHHHEINFIYKVVSRETVPPSFLIgRTEAEDGQYFQAEVFLREGGQNYDVMDWTQEDLIQD 638
Cdd:PRK09928  573 LNELPPEederlghLDLLVHLGDEQNFVYQIWPQRYSVPGFTY-RARSGKSTYYRLETFLLEGSQGNDLMDYSKEQVIND 651
                         650
                  ....*....|....*.
gi 2105040256 639 IIDQYERHLYFLNIVR 654
Cdd:PRK09928  652 ILDQYERHLNFLHLHR 667
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
16-498 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 625.33  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  16 VFFGTVIIIALFLAVVVIAPSSFELLTQQLKQWITDSFSWFYVLSVAFFLILLIYIACSSIGRIKLGPDHSQPEYNNGSW 95
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  96 FAMLFTAGMGIGLMFFGVAEPVMHYVN-PPSGDAQTIDAAQQALRVTFFHWGLHAWAIYAVVGLALAYFAYRHNLPLKTR 174
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 175 SALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFGVTQINSGLHYLFGVEQSTHIQVLLIIFVSILASLSVFLGLDK 254
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 255 GVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTGQYISNLFTMTFNLYAYQPNG-WIGGWTILYWAWWISWSPFVG 333
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTGgWLGGWTIFYWAWWIAWAPFVG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 334 MFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAALFsIIHEHQTTLIQAVQQDSSVALFEFLGHLPWSGVMNILAT 413
Cdd:pfam02028 321 MFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIY-LELNGPGDLADAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 414 ILVVLFFVTSADSGALVTDYLTAK-TENSPTWQRLFWTVLMAVLAIILLLVGGLAALQSSIIMSALPFTVVMLLMSWGLI 492
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGgDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISLF 479

                  ....*.
gi 2105040256 493 KALHLD 498
Cdd:pfam02028 480 KALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
54-498 3.42e-169

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 491.10  E-value: 3.42e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  54 SWFYVLSVAFFLILLIYIACSSIGRIKLGPDHSQPEYNNGSWFAMLFTAGMGIGLMFFGVAEPVMHYVNPPSGDAQTI-D 132
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTStT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 133 AAQQALRVTFFHWGLHAWAIYAVVGLALAYFAYRHNLPLKTRSALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFG 212
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 213 VTQINSGLHYLFGVEQSTHIQVLLIIFVSILASLSVFLGLDKGVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTG 292
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 293 QYISNLFTMTFNLYAYQ-PNGWIGGWTILYWAWWISWSPFVGMFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAA 371
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDgKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNSA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 372 LFSIIHEHQTTLIQAVQQDSSVALFEFLGHLPWSGVMNILATILVVLFFVTSADSGALVTDYLTAKT----ENSPTWQRL 447
Cdd:TIGR00842 321 LLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlgEEPPKWVRV 400
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2105040256 448 FWTVLMAVLAI-ILLLVGGLAALQSSIIMSALPFTVVMLLMSWGLIKALHLD 498
Cdd:TIGR00842 401 FWAVAIGLIALvLLFSGGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
3-509 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 680.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256   3 SKQPGWFANVNPNVFFGTVIIIALFLAVVVIAPSSFELLTQQLKQWITDSFSWFYVLSVAFFLILLIYIACSSIGRIKLG 82
Cdd:COG1292     4 KNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  83 PDHSQPEYNNGSWFAMLFTAGMGIGLMFFGVAEPVMHYVNPPSG-DAQTIDAAQQALRVTFFHWGLHAWAIYAVVGLALA 161
Cdd:COG1292    84 GDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALA 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 162 YFAYRHNLPLKTRSALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFGVTQINSGLHYLFGVEQSTHIQVLLIIFVS 241
Cdd:COG1292   164 YFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVIT 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 242 ILASLSVFLGLDKGVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTGQYISNLFTMTFNLYAYQPNGWIGGWTILY 321
Cdd:COG1292   244 ALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGDTGWLGGWTVFY 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 322 WAWWISWSPFVGMFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAALFSIIHEhQTTLIQAVQQDSSVALFEFLGH 401
Cdd:COG1292   324 WAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNG-GGDLAEAVAAGVEAALFALLEQ 402
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 402 LPWSGVMNILATILVVLFFVTSADSGALVTDYLTAK-TENSPTWQRLFWTVLMAVLAIILLLVGGLAALQSSIIMSALPF 480
Cdd:COG1292   403 LPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGgDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALPF 482
                         490       500
                  ....*....|....*....|....*....
gi 2105040256 481 TVVMLLMSWGLIKALHLDVTKMTAIQEAR 509
Cdd:COG1292   483 SFVLLLMCVSLVKALREDPRRLRSAEAEA 511
PRK09928 PRK09928
choline transport protein BetT; Provisional
12-654 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 639.05  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  12 VNPNVFFGTVIIIALFLAVVVIAPSSFELLTQQLKQWITDSFSWFYVLSVAFFLILLIYIACSSIGRIKLGPDHSQPEYN 91
Cdd:PRK09928   15 INPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQSKPEFS 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  92 NGSWFAMLFTAGMGIGLMFFGVAEPVMHYVNPPSGDAQTIDAAQQALRVTFFHWGLHAWAIYAVVGLALAYFAYRHNLPL 171
Cdd:PRK09928   95 LLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPL 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 172 KTRSALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFGVTQINSGLHYLFGVEQSTHIQVLLIIFVSILASLSVFLG 251
Cdd:PRK09928  175 TIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSVIIATISVTSG 254
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 252 LDKGVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTGQYISNLFTMTFNLYAY-QPNGWIGGWTILYWAWWISWSP 330
Cdd:PRK09928  255 VNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFdRPTEWMNNWTLFFWAWWVAWSP 334
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 331 FVGMFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAALFSIIHEHQtTLIQAVQQDSSVALFEFLGHLPWSGVMNI 410
Cdd:PRK09928  335 FVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNA-AFAEEAMAHPERGFYSLLAQYPAFTFSAS 413
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 411 LATILVVLFFVTSADSGALVTDYLTAKTEN----SPTWQRLFWTVLMAVLAIILLLVGGLAALQSSIIMSALPFTVVMLL 486
Cdd:PRK09928  414 VATITGLLFYVTSADSGALVLGNFTSKLKDinsdAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFF 493
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 487 MSWGLIKALHL-DVTKMTAIQEARITPRAIHNPRSWQQRLGLIMHYPHSeEEVREYIEKQVSRAFENIKHEFRRRHLEVS 565
Cdd:PRK09928  494 VMAGLYKSLKVeDYRRASANRDTAPRLVGLQDRLNWKQRLSRVMNYPGT-RYTRRMLDTVCRPAMEEVAQELRLRGAYVE 572
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 566 ITQLEDG-------MQLRVDHHHEINFIYKVVSRETVPPSFLIgRTEAEDGQYFQAEVFLREGGQNYDVMDWTQEDLIQD 638
Cdd:PRK09928  573 LNELPPEederlghLDLLVHLGDEQNFVYQIWPQRYSVPGFTY-RARSGKSTYYRLETFLLEGSQGNDLMDYSKEQVIND 651
                         650
                  ....*....|....*.
gi 2105040256 639 IIDQYERHLYFLNIVR 654
Cdd:PRK09928  652 ILDQYERHLNFLHLHR 667
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
16-498 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 625.33  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  16 VFFGTVIIIALFLAVVVIAPSSFELLTQQLKQWITDSFSWFYVLSVAFFLILLIYIACSSIGRIKLGPDHSQPEYNNGSW 95
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  96 FAMLFTAGMGIGLMFFGVAEPVMHYVN-PPSGDAQTIDAAQQALRVTFFHWGLHAWAIYAVVGLALAYFAYRHNLPLKTR 174
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 175 SALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFGVTQINSGLHYLFGVEQSTHIQVLLIIFVSILASLSVFLGLDK 254
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 255 GVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTGQYISNLFTMTFNLYAYQPNG-WIGGWTILYWAWWISWSPFVG 333
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTGgWLGGWTIFYWAWWIAWAPFVG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 334 MFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAALFsIIHEHQTTLIQAVQQDSSVALFEFLGHLPWSGVMNILAT 413
Cdd:pfam02028 321 MFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIY-LELNGPGDLADAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 414 ILVVLFFVTSADSGALVTDYLTAK-TENSPTWQRLFWTVLMAVLAIILLLVGGLAALQSSIIMSALPFTVVMLLMSWGLI 492
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGgDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISLF 479

                  ....*.
gi 2105040256 493 KALHLD 498
Cdd:pfam02028 480 KALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
54-498 3.42e-169

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 491.10  E-value: 3.42e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  54 SWFYVLSVAFFLILLIYIACSSIGRIKLGPDHSQPEYNNGSWFAMLFTAGMGIGLMFFGVAEPVMHYVNPPSGDAQTI-D 132
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTStT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 133 AAQQALRVTFFHWGLHAWAIYAVVGLALAYFAYRHNLPLKTRSALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFG 212
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 213 VTQINSGLHYLFGVEQSTHIQVLLIIFVSILASLSVFLGLDKGVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTG 292
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 293 QYISNLFTMTFNLYAYQ-PNGWIGGWTILYWAWWISWSPFVGMFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAA 371
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDgKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNSA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 372 LFSIIHEHQTTLIQAVQQDSSVALFEFLGHLPWSGVMNILATILVVLFFVTSADSGALVTDYLTAKT----ENSPTWQRL 447
Cdd:TIGR00842 321 LLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlgEEPPKWVRV 400
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2105040256 448 FWTVLMAVLAI-ILLLVGGLAALQSSIIMSALPFTVVMLLMSWGLIKALHLD 498
Cdd:TIGR00842 401 FWAVAIGLIALvLLFSGGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09950 PRK09950
putative transporter; Provisional
11-504 1.12e-68

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 232.37  E-value: 1.12e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  11 NVNPNVFFGTVIIIALFLAVVVIA--PSSFELLTQQLKQWITDSFSWFYVLSVAFFLILLIYIACSSIGRIKLGpdHSQP 88
Cdd:PRK09950    5 KKKKDKPLISTSLLAVFFIVAALSlfPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLG--EGKP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  89 EYNNGSWFAMLFTAGMGIGLMFFGVAEPVMHYVNPP-SGDAQTIDAAQQALRVTFFHWGLHAWAIYAVVGLALAY-FAYR 166
Cdd:PRK09950   83 EYSTLSWLFMFICAGLGSSTLYWGVMEWAYYYQTPGlNIAPRSPKALEYSVSYSFFHWGISAWATYALASLIMAYhFHVR 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 167 HNLPLKTRSALYPLIGKKIYGPWGDSIDIFATIGTVFGVATSLGFGVTQINSGLHYLFGVEQSTHIQVLLIIFVSILASL 246
Cdd:PRK09950  163 KNKGLSLSGIIAAITGVKPQGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIFCL 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 247 SVFLGLDKGVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTGQYISNLFTMTFNLYAYQPNGWIGGWTILYWAWWI 326
Cdd:PRK09950  243 SSYIGIDNGLQRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFLQMSLFTDPMGDGSFTRNWTVFYWLWWI 322
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 327 SWSPFVGMFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAALFSIIHEHQTTLIQAVQQDSSVALFEFLGHLPWSG 406
Cdd:PRK09950  323 SYTPGVAMFVTRVSRGRKIKEVIWGLILGSSVGCWFFFGVLESYAIHQFINGVINVPQILNTLGGETAVQQLLSSLPAGK 402
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 407 VMNILATILVVLFFVTSADS-----GALVTDYLTAKTENSPTwQRLFWTVLMAVLAI-ILLLVGGLAALQSSIIMSALPF 480
Cdd:PRK09950  403 LFLAAYLGIMIIFLASHMDAvaytmAATSTRNLREGDDPDRG-LRLFWCVVITLIPLsILFTGASLDTMKTTVVLTALPF 481
                         490       500
                  ....*....|....*....|....
gi 2105040256 481 TVVMLLMSWGLIKALHLDVTKMTA 504
Cdd:PRK09950  482 LVILLIKVYGFIRWLKQDYADVPA 505
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
12-493 1.51e-66

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 226.92  E-value: 1.51e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  12 VNPNVFFGTVIIIALFLAVVVIAPSSFELLTQQLKQWITDSFSWFYVLSVAFFLILLIYIACSSIGRIKLGPDhsQPEYN 91
Cdd:PRK03356   10 IEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDE--KPEFS 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256  92 NGSWFAMLFTAGMGIGLMFFGVAEPVMHYVNPPSG-DAQTIDAAQQALRVTFFHWGLHAWAIYAVVGLALAYFAY-RHNL 169
Cdd:PRK03356   88 TASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGlEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFFFvRKMD 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 170 PLKTRSALYPLIGKK-IYGPWGDSIDIFATIGTVFGVATSLGFGVTQINSGLHYLFGVEQSTHIQVLLIIFVSILASLSV 248
Cdd:PRK03356  168 VIRPSSTLVPLVGEKhAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICV 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 249 FLGLDKGVKRLSELNLVLALILLAFVFIAGPSIYLLQTTIQNTGQYISNLFTMTFNLYAYQPNGWIGGWTILYWAWWISW 328
Cdd:PRK03356  248 ACGLQKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPIGKGGFPQGWTVFYWAWWVIY 327
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 329 SPFVGMFIARVSRGRTIREFIVGVLLIPTGFTIIWMGFLGNAALFsIIHEHQTTLIQAVQQDSSV-ALFEFLGHLPWSGV 407
Cdd:PRK03356  328 AIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLL-LMDKNIINIPNLIEQYGVArAIIETWAALPLSTA 406
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2105040256 408 MNILATILVVLFFVTSADSG----ALVTDYLTAKTENSPTWQRLFWTVLMAVLAIILLLVGGLAALQSSIIMSALPFTVV 483
Cdd:PRK03356  407 TMWGFFILCFIATVTLINACsytlAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFV 486
                         490
                  ....*....|
gi 2105040256 484 MLLMSWGLIK 493
Cdd:PRK03356  487 NIMVTLSFIK 496
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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