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Conserved domains on  [gi|2107157020|ref|WP_225525649|]
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MULTISPECIES: NAD(P)-binding protein [Pseudomonas]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG1233 super family cl34198
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 3-39 1.48e-08

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


The actual alignment was detected with superfamily member COG1233:

Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 49.08  E-value: 1.48e-08
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2107157020   3 RTYDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHP 39
Cdd:COG1233     2 MMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTP 38
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 3-39 1.48e-08

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 49.08  E-value: 1.48e-08
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2107157020   3 RTYDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHP 39
Cdd:COG1233     2 MMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTP 38
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 5-41 2.29e-07

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 45.77  E-value: 2.29e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHPRF 41
Cdd:TIGR02032   1 YDVVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRY 37
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
9-39 1.01e-06

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 41.36  E-value: 1.01e-06
                         10        20        30
                 ....*....|....*....|....*....|.
gi 2107157020  9 IIGSGIAGSISAAILAKHGLKTLILDAGQHP 39
Cdd:pfam13450  1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRL 31
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 1-44 2.45e-06

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 42.96  E-value: 2.45e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAKHGLKTLILDagQHPRFSIG 44
Cdd:PRK12834    1 MAMDADVIVVGAGLAGLVAAAELADAGKRVLLLD--QENEANLG 42
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 3-39 1.48e-08

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 49.08  E-value: 1.48e-08
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2107157020   3 RTYDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHP 39
Cdd:COG1233     2 MMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTP 38
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
5-37 1.18e-07

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 46.27  E-value: 1.18e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2107157020   5 YDIVIIGSGIAGsISAAI-LAKHGLKTLILDAGQ 37
Cdd:COG0492     1 YDVVIIGAGPAG-LTAAIyAARAGLKTLVIEGGE 33
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 5-41 2.29e-07

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 45.77  E-value: 2.29e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHPRF 41
Cdd:TIGR02032   1 YDVVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRY 37
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
9-39 1.01e-06

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 41.36  E-value: 1.01e-06
                         10        20        30
                 ....*....|....*....|....*....|.
gi 2107157020  9 IIGSGIAGSISAAILAKHGLKTLILDAGQHP 39
Cdd:pfam13450  1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRL 31
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 2-36 1.21e-06

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 43.54  E-value: 1.21e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2107157020   2 SRTYDIVIIGSGIAGSISAAILAKHGLKTLILDAG 36
Cdd:COG1249     1 MKDYDLVVIGAGPGGYVAAIRAAQLGLKVALVEKG 35
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
13-43 1.65e-06

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 43.03  E-value: 1.65e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2107157020  13 GIAGSISAAILAKHGLKTLILDAGQHPRFSI 43
Cdd:COG0644     2 GPAGSAAARRLARAGLSVLLLEKGSFPGDKI 32
glycerol3P_GlpB TIGR03378
glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are ...
 5-37 1.73e-06

glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are the B subunit, product of the glpB gene, of a three-subunit, membrane-anchored, FAD-dependent anaerobic glycerol-3-phosphate dehydrogenase. [Energy metabolism, Anaerobic]


Pssm-ID: 213807  Cd Length: 419  Bit Score: 43.08  E-value: 1.73e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2107157020   5 YDIVIIGSGIAGsISAAI-LAKHGLKTLILDAGQ 37
Cdd:TIGR03378   1 FDVIIIGGGLAG-LSCALrLAEAGKKCAIIAAGQ 33
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
3-37 2.09e-06

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 42.97  E-value: 2.09e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2107157020   3 RTYDIVIIGSGIAGSISAAILAKHGLKTLILDAGQ 37
Cdd:COG0665     1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGR 35
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 1-44 2.45e-06

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 42.96  E-value: 2.45e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAKHGLKTLILDagQHPRFSIG 44
Cdd:PRK12834    1 MAMDADVIVVGAGLAGLVAAAELADAGKRVLLLD--QENEANLG 42
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 3-33 3.08e-06

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 42.51  E-value: 3.08e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2107157020   3 RTYDIVIIGSGIAGsISAAI-LAKHGLKTLIL 33
Cdd:COG1053     2 HEYDVVVVGSGGAG-LRAALeAAEAGLKVLVL 32
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 1-40 3.31e-06

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 42.51  E-value: 3.31e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAKH-GLKTLILDAGQHPR 40
Cdd:COG2303     1 MLEEYDYVIVGAGSAGCVLANRLSEDaGLRVLLLEAGGRDD 41
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
5-37 4.03e-06

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 42.14  E-value: 4.03e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILDAGQ 37
Cdd:PRK05329    3 FDVLVIGGGLAGLTAALAAAEAGKRVALVAKGQ 35
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 6-39 6.87e-06

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 41.61  E-value: 6.87e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2107157020   6 DIVIIGSGIAGSISAAILAKHGLKTLILDAGQHP 39
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDP 34
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 3-36 9.24e-06

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 41.32  E-value: 9.24e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2107157020   3 RTYDIVIIGSGIAGSISAAILAKHGLKTLILDAG 36
Cdd:PRK06292    2 EKYDVIVIGAGPAGYVAARRAAKLGKKVALIEKG 35
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 6-37 1.35e-05

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 40.73  E-value: 1.35e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2107157020   6 DIVIIGSGIAGsISAAI-LAKHGLKTLILDAGQ 37
Cdd:pfam00890   1 DVLVIGGGLAG-LAAALaAAEAGLKVAVVEKGQ 32
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 6-40 2.18e-05

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 40.26  E-value: 2.18e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2107157020   6 DIVIIGSGIAGSISAAILAKHGLKTLILDAGQHPR 40
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALARSGLKVALIEATPLPA 35
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 2-41 2.59e-05

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 39.92  E-value: 2.59e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2107157020   2 SRTYDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHPRF 41
Cdd:COG0654     1 MMRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRP 40
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 5-34 2.94e-05

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 39.81  E-value: 2.94e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILD 34
Cdd:TIGR01377   1 FDVIVVGAGIMGCFAAYHLAKHGKKTLLLE 30
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-36 3.07e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 39.85  E-value: 3.07e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2107157020   1 MSRTYDIVIIGSGIAGsISAAI-LAKHGLKTLILDAG 36
Cdd:COG2072     3 ATEHVDVVVIGAGQAG-LAAAYhLRRAGIDFVVLEKA 38
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 5-36 3.73e-05

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.22  E-value: 3.73e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2107157020   5 YDIVIIGSGIAGsISAAI-LAKHGLKTLILDAG 36
Cdd:pfam07992   1 YDVVVIGGGPAG-LAAALtLAQLGGKVTLIEDE 32
PRK12844 PRK12844
3-ketosteroid-delta-1-dehydrogenase; Reviewed
 3-34 8.05e-05

3-ketosteroid-delta-1-dehydrogenase; Reviewed


Pssm-ID: 183787 [Multi-domain]  Cd Length: 557  Bit Score: 38.58  E-value: 8.05e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2107157020   3 RTYDIVIIGSGIAGSISAAILAKHGLKTLILD 34
Cdd:PRK12844    5 ETYDVVVVGSGGGGMCAALAAADSGLEPLIVE 36
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 2-47 8.23e-05

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 38.68  E-value: 8.23e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2107157020   2 SRTYDIVIIGSGIAGSISAAILAKHGLKTLIL--DAGQHPRFSIGEAM 47
Cdd:PTZ00367   31 NYDYDVIIVGGSIAGPVLAKALSKQGRKVLMLerDLFSKPDRIVGELL 78
PRK11445 PRK11445
FAD-binding protein;
5-34 9.12e-05

FAD-binding protein;


Pssm-ID: 183139 [Multi-domain]  Cd Length: 351  Bit Score: 38.50  E-value: 9.12e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHgLKTLILD 34
Cdd:PRK11445    2 YDVAIIGLGPAGSALARLLAGK-MKVIAID 30
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 5-41 1.02e-04

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 38.20  E-value: 1.02e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2107157020   5 YDIVIIGSGIAGSISAAILAK----HGLKTLILDAGQHPRF 41
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNnpltKDLKVLLLDAVDNPKL 41
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
5-44 1.14e-04

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 38.24  E-value: 1.14e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILDagQHPRFSIG 44
Cdd:COG3573     6 ADVIVVGAGLAGLVAAAELADAGRRVLLLD--QEPEANLG 43
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 1-27 1.28e-04

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 37.78  E-value: 1.28e-04
                          10        20
                  ....*....|....*....|....*...
gi 2107157020   1 MSRTYDIVIIGSGIAGsISAAI-LAKHG 27
Cdd:COG0029     1 ERLKTDVLVIGSGIAG-LSAALkLAERG 27
PRK07843 PRK07843
3-oxosteroid 1-dehydrogenase;
4-38 1.32e-04

3-oxosteroid 1-dehydrogenase;


Pssm-ID: 236111 [Multi-domain]  Cd Length: 557  Bit Score: 38.09  E-value: 1.32e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2107157020   4 TYDIVIIGSGIAGSISAAILAKHGLKTLILDAGQH 38
Cdd:PRK07843    7 EYDVVVVGSGAAGMVAALTAAHRGLSTVVVEKAPH 41
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
1-38 1.41e-04

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 37.82  E-value: 1.41e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAK-HGLKTLIL----DAGQH 38
Cdd:COG0579     1 MMEMYDVVIIGAGIVGLALARELSRyEDLKVLVLekedDVAQE 43
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 6-38 1.79e-04

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 37.59  E-value: 1.79e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2107157020   6 DIVIIGSGIAGsISAAI-LAKHGLKTLILDAGQH 38
Cdd:pfam12831   1 DVVVVGGGPAG-VAAAIaAARAGAKVLLVERRGF 33
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
1-35 1.84e-04

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 37.59  E-value: 1.84e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2107157020   1 MSR---TYDIVIIGSGIAGSISAAILAKHGLKTLILDA 35
Cdd:COG1231     1 MSRrarGKDVVIVGAGLAGLAAARELRKAGLDVTVLEA 38
PRK07364 PRK07364
FAD-dependent hydroxylase;
4-35 2.10e-04

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 37.31  E-value: 2.10e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2107157020   4 TYDIVIIGSGIAGSISAAILAKHGLKTLILDA 35
Cdd:PRK07364   18 TYDVAIVGGGIVGLTLAAALKDSGLRIALIEA 49
PRK10157 PRK10157
putative oxidoreductase FixC; Provisional
 5-39 2.34e-04

putative oxidoreductase FixC; Provisional


Pssm-ID: 182273 [Multi-domain]  Cd Length: 428  Bit Score: 37.20  E-value: 2.34e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHP 39
Cdd:PRK10157    6 FDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSA 40
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
1-37 2.44e-04

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 37.06  E-value: 2.44e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2107157020   1 MSRTYDIVIIGSGIAGSiSAAI-LAKHGLKTLILDAGQ 37
Cdd:PRK05249    2 HMYDYDLVVIGSGPAGE-GAAMqAAKLGKRVAVIERYR 38
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
3-36 2.97e-04

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 36.78  E-value: 2.97e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2107157020   3 RTYDIVIIGSGIAGSISAAILAKHGLKTLILDAG 36
Cdd:COG3380     2 SMPDIAIIGAGIAGLAAARALQDAGHEVTVFEKS 35
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
1-40 3.91e-04

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 36.47  E-value: 3.91e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHPR 40
Cdd:PRK07608    2 YHMKFDVVVVGGGLVGASLALALAQSGLRVALLAPRAPPR 41
Trp_halogenase pfam04820
Tryptophan halogenase; Tryptophan halogenase catalyzes the chlorination of tryptophan to form ...
 6-46 4.20e-04

Tryptophan halogenase; Tryptophan halogenase catalyzes the chlorination of tryptophan to form 7-chlorotryptophan. This is the first step in the biosynthesis of pyrrolnitrin, an antibiotic with broad-spectrum anti-fungal activity. Tryptophan halogenase is NADH-dependent.


Pssm-ID: 398475 [Multi-domain]  Cd Length: 457  Bit Score: 36.54  E-value: 4.20e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2107157020   6 DIVIIGSGIAGSISAAILAKHGLKTL---ILDAGQHPRFSIGEA 46
Cdd:pfam04820   1 KIVIVGGGTAGWMAAAALARALKGGLdvtLVESEEIGTVGVGEA 44
PRK12839 PRK12839
FAD-dependent oxidoreductase;
1-34 4.49e-04

FAD-dependent oxidoreductase;


Pssm-ID: 237223 [Multi-domain]  Cd Length: 572  Bit Score: 36.35  E-value: 4.49e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2107157020   1 MSRTYDIVIIGSGiAGSISAAILAKH-GLKTLILD 34
Cdd:PRK12839    5 MTHTYDVVVVGSG-AGGLSAAVAAAYgGAKVLVVE 38
PRK10015 PRK10015
oxidoreductase; Provisional
 5-36 4.95e-04

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 36.49  E-value: 4.95e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILDAG 36
Cdd:PRK10015    6 FDAIVVGAGVAGSVAALVMARAGLDVLVIERG 37
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 1-36 5.14e-04

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 36.28  E-value: 5.14e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2107157020   1 MSRTYDIVIIGSGIAGsISAAI-LAKHGLKTLILDAG 36
Cdd:PRK06416    1 FAFEYDVIVIGAGPGG-YVAAIrAAQLGLKVAIVEKE 36
PRK06481 PRK06481
flavocytochrome c;
1-34 5.25e-04

flavocytochrome c;


Pssm-ID: 180584 [Multi-domain]  Cd Length: 506  Bit Score: 36.35  E-value: 5.25e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2107157020   1 MSRTYDIVIIGSGIAGsISAAILAKH-GLKTLILD 34
Cdd:PRK06481   58 LKDKYDIVIVGAGGAG-MSAAIEAKDaGMNPVILE 91
PRK12835 PRK12835
3-ketosteroid-delta-1-dehydrogenase; Reviewed
 3-38 5.72e-04

3-ketosteroid-delta-1-dehydrogenase; Reviewed


Pssm-ID: 237221 [Multi-domain]  Cd Length: 584  Bit Score: 36.32  E-value: 5.72e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2107157020   3 RTYDIVIIGSGiAGSISAAILAKH-GLKTLILDAGQH 38
Cdd:PRK12835   10 REVDVLVVGSG-GGGMTAALTAAArGLDTLVVEKSAH 45
PRK06370 PRK06370
FAD-containing oxidoreductase;
1-30 9.64e-04

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 35.56  E-value: 9.64e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAKHGLKT 30
Cdd:PRK06370    2 PAQRYDAIVIGAGQAGPPLAARAAGLGMKV 31
GIDA pfam01134
Glucose inhibited division protein A;
6-33 9.73e-04

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 35.60  E-value: 9.73e-04
                          10        20
                  ....*....|....*....|....*...
gi 2107157020   6 DIVIIGSGIAGSISAAILAKHGLKTLIL 33
Cdd:pfam01134   1 DVIVIGGGHAGCEAALAAARMGAKVLLI 28
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 5-47 9.92e-04

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 35.52  E-value: 9.92e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHPRFSIGEAM 47
Cdd:PRK08849    4 YDIAVVGGGMVGAATALGFAKQGRSVAVIEGGEPKAFEPSQPM 46
solA PRK11259
N-methyl-L-tryptophan oxidase;
2-35 2.04e-03

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 34.43  E-value: 2.04e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2107157020   2 SRTYDIVIIGSGIAGSISAAILAKHGLKTLILDA 35
Cdd:PRK11259    1 TMRYDVIVIGLGSMGSAAGYYLARRGLRVLGLDR 34
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
1-34 2.09e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 34.49  E-value: 2.09e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAKHGLKTLILD 34
Cdd:PRK07494    4 EKEHTDIAVIGGGPAGLAAAIALARAGASVALVA 37
PRK02106 PRK02106
choline dehydrogenase; Validated
 1-36 2.63e-03

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 34.04  E-value: 2.63e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAKHG-LKTLILDAG 36
Cdd:PRK02106    2 TTMEYDYIIIGAGSAGCVLANRLSEDPdVSVLLLEAG 38
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 5-39 3.25e-03

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 34.04  E-value: 3.25e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2107157020   5 YDIVIIGSGIAGsISAA-ILAKHGLKTLILDAGQHP 39
Cdd:COG1232     2 KRVAVIGGGIAG-LTAAyRLAKAGHEVTVLEASDRV 36
PRK12842 PRK12842
putative succinate dehydrogenase; Reviewed
 3-34 4.42e-03

putative succinate dehydrogenase; Reviewed


Pssm-ID: 237224 [Multi-domain]  Cd Length: 574  Bit Score: 33.51  E-value: 4.42e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2107157020   3 RTYDIVIIGSGiAGSISAAILA-KHGLKTLILD 34
Cdd:PRK12842    8 LTCDVLVIGSG-AGGLSAAITArKLGLDVVVLE 39
MnmG COG0445
tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal ...
 1-33 4.58e-03

tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal structure and biogenesis]; tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440214 [Multi-domain]  Cd Length: 626  Bit Score: 33.44  E-value: 4.58e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAKHGLKTLIL 33
Cdd:COG0445     3 YPKEYDVIVVGGGHAGCEAALAAARMGAKTLLL 35
PTZ00052 PTZ00052
thioredoxin reductase; Provisional
 5-34 5.18e-03

thioredoxin reductase; Provisional


Pssm-ID: 185416 [Multi-domain]  Cd Length: 499  Bit Score: 33.26  E-value: 5.18e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILD 34
Cdd:PTZ00052    6 YDLVVIGGGSGGMAAAKEAAAHGKKVALFD 35
TGR TIGR01438
thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member ...
 5-35 5.87e-03

thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member of the pyridine nucleotide disulfide oxidoreductase family contains a C-terminal motif Cys-SeCys-Gly, where SeCys is selenocysteine encoded by TGA (in some sequence reports interpreted as a stop codon). In some members of this subfamily, Cys-SeCys-Gly is replaced by Cys-Cys-Gly. The reach of the selenium atom at the C-term arm of the protein is proposed to allow broad substrate specificity.


Pssm-ID: 273624 [Multi-domain]  Cd Length: 484  Bit Score: 33.29  E-value: 5.87e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2107157020   5 YDIVIIGSGIAGSISAAILAKHGLKTLILDA 35
Cdd:TIGR01438   3 YDLIVIGGGSGGLAAAKEAAAYGAKVMLLDF 33
PLN02576 PLN02576
protoporphyrinogen oxidase
 2-35 6.11e-03

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 33.06  E-value: 6.11e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2107157020   2 SRTYDIVIIGSGIAGSISAAILA-KHGLKTLILDA 35
Cdd:PLN02576   10 ASSKDVAVVGAGVSGLAAAYALAsKHGVNVLVTEA 44
PRK06327 PRK06327
dihydrolipoamide dehydrogenase; Validated
 1-39 6.47e-03

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235779 [Multi-domain]  Cd Length: 475  Bit Score: 32.98  E-value: 6.47e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2107157020   1 MSRTYDIVIIGSGIAGSISAAILAKHGLKTLILDAGQHP 39
Cdd:PRK06327    1 MSKQFDVVVIGAGPGGYVAAIRAAQLGLKVACIEAWKNP 39
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 7-39 6.61e-03

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 32.86  E-value: 6.61e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2107157020   7 IVIIGSGIAGSISAAILAKHGLKTLILDAGQHP 39
Cdd:COG0446   127 AVVIGGGPIGLELAEALRKRGLKVTLVERAPRL 159
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
1-42 7.50e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 32.91  E-value: 7.50e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2107157020   1 MSRTY--DIVIIGSGIAGSISAAILAKHGLKTLILDAGQHPRFS 42
Cdd:PRK08773    1 MSRRSrrDAVIVGGGVVGAACALALADAGLSVALVEGREPPRWQ 44
PRK08274 PRK08274
FAD-dependent tricarballylate dehydrogenase TcuA;
1-41 8.73e-03

FAD-dependent tricarballylate dehydrogenase TcuA;


Pssm-ID: 236214 [Multi-domain]  Cd Length: 466  Bit Score: 32.92  E-value: 8.73e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2107157020   1 MSRTYDIVIIGSGIAGsISAAILAK-HGLKTLILDAGqhPRF 41
Cdd:PRK08274    1 MASMVDVLVIGGGNAA-LCAALAAReAGASVLLLEAA--PRE 39
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
6-47 8.95e-03

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 32.90  E-value: 8.95e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2107157020   6 DIVIIGSGIAGSISAAILAKHGLKTLILDAGqHPRFSIGEAM 47
Cdd:PRK13800   15 DVLVIGGGTAGTMAALTAAEHGANVLLLEKA-HVRHSGALAM 55
sdhA PRK06069
succinate dehydrogenase/fumarate reductase flavoprotein subunit;
4-25 9.48e-03

succinate dehydrogenase/fumarate reductase flavoprotein subunit;


Pssm-ID: 235689 [Multi-domain]  Cd Length: 577  Bit Score: 32.72  E-value: 9.48e-03
                          10        20
                  ....*....|....*....|..
gi 2107157020   4 TYDIVIIGSGIAGsISAAILAK 25
Cdd:PRK06069    5 KYDVVIVGSGLAG-LRAAVAAA 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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