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Conserved domains on  [gi|2124835902|ref|WP_227068893|]
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glycine betaine ABC transporter substrate-binding protein [Veillonella atypica]

Protein Classification

TM_PBP2 and PBP2_ProWX domain-containing protein( domain architecture ID 10787290)

TM_PBP2 and PBP2_ProWX domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PBP2_ProWX cd13612
Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; ...
243-509 0e+00

Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWX of Helicobacter pylori is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


:

Pssm-ID: 270330  Cd Length: 267  Bit Score: 523.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 243 VIHVATKPMTEQLILGDMLKLLIEQDTDLTVEVTAGVGGGTSNIQPAMESGQFDIYPEYTGTGWNAVLKRDTQYSENLFD 322
Cdd:cd13612     1 TIHIATKPMTEQYILGEMLKQLIEQDTDLKVELTKGVGGGTSNIHPAMVKGEFDLYPEYTGTGWLFVLKKDGTYSEELFD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 323 ELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGMDFKDT 402
Cdd:cd13612    81 QLQKEYEEKYNLTWLGLYGFNNTYGLAVRKELAEKYNLKTYSDLAKVSNQLVFGAEYDFFEREDGYDALQKAYGFNFKKT 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 403 KDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITDQDM 482
Cdd:cd13612   161 VDMDIGLKYQAIESGKVDVINVFTTDGQLSDADIVVLEDDKGFFPSYYAGTVVREETLEKYPELEDVLEKLTGLISDEDM 240
                         250       260
                  ....*....|....*....|....*..
gi 2124835902 483 SYMNYEVESEGQKPHDVAERYLRIKGL 509
Cdd:cd13612   241 AEMNYQVEIEKKDPKDVAKEFLEEKGL 267
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
1-210 1.35e-85

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 262.68  E-value: 1.35e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902   1 MIQNIYHLLVENWSFFSGLLWEHIGIALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGI 80
Cdd:COG1174     1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  81 GNATAVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFI 160
Cdd:COG1174    81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2124835902 161 GAGGLGVAIYRGITTNNTTMTVAGSLLIAFLALIMDAVLGFFEKIILYRG 210
Cdd:COG1174   161 GAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPRG 210
 
Name Accession Description Interval E-value
PBP2_ProWX cd13612
Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; ...
243-509 0e+00

Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWX of Helicobacter pylori is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270330  Cd Length: 267  Bit Score: 523.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 243 VIHVATKPMTEQLILGDMLKLLIEQDTDLTVEVTAGVGGGTSNIQPAMESGQFDIYPEYTGTGWNAVLKRDTQYSENLFD 322
Cdd:cd13612     1 TIHIATKPMTEQYILGEMLKQLIEQDTDLKVELTKGVGGGTSNIHPAMVKGEFDLYPEYTGTGWLFVLKKDGTYSEELFD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 323 ELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGMDFKDT 402
Cdd:cd13612    81 QLQKEYEEKYNLTWLGLYGFNNTYGLAVRKELAEKYNLKTYSDLAKVSNQLVFGAEYDFFEREDGYDALQKAYGFNFKKT 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 403 KDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITDQDM 482
Cdd:cd13612   161 VDMDIGLKYQAIESGKVDVINVFTTDGQLSDADIVVLEDDKGFFPSYYAGTVVREETLEKYPELEDVLEKLTGLISDEDM 240
                         250       260
                  ....*....|....*....|....*..
gi 2124835902 483 SYMNYEVESEGQKPHDVAERYLRIKGL 509
Cdd:cd13612   241 AEMNYQVEIEKKDPKDVAKEFLEEKGL 267
OsmF COG1732
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system ...
237-505 6.42e-116

Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441338 [Multi-domain]  Cd Length: 294  Bit Score: 343.67  E-value: 6.42e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 237 PSQQSDVIHVATKPMTEQLILGDMLKLLIEqDTDLTVEVTAGVGGgTSNIQPAMESGQFDIYPEYTGTGWNAVLKRDTQY 316
Cdd:COG1732    25 AAAAGDTIVVGSKNFTEQEILAEIYAQALE-AAGLKVERKLNLGG-TEVVRQALKSGEIDLYPEYTGTALTTYLKEDPIT 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 317 S-ENLFDELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVY 395
Cdd:COG1732   103 DpEEVYEAVKEALPEKNGLTWLDPAGFNNTYALAVTKETAEKYGLKTISDLAKVAGELTLGADPEFAERPDGLPGLKKAY 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 396 GMDFKDTKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTN 475
Cdd:COG1732   183 GFEFKEVKPMDTGLTYTALANGQVDVADAYTTDGRIAALDLVVLEDDKNFFPPYNAAPLVRKEVLEKYPELAEVLNKLSG 262
                         250       260       270
                  ....*....|....*....|....*....|
gi 2124835902 476 TITDQDMSYMNYEVESEGQKPHDVAERYLR 505
Cdd:COG1732   263 KLTTETMQELNYQVDVDGEDPADVAREFLK 292
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
1-210 1.35e-85

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 262.68  E-value: 1.35e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902   1 MIQNIYHLLVENWSFFSGLLWEHIGIALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGI 80
Cdd:COG1174     1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  81 GNATAVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFI 160
Cdd:COG1174    81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2124835902 161 GAGGLGVAIYRGITTNNTTMTVAGSLLIAFLALIMDAVLGFFEKIILYRG 210
Cdd:COG1174   161 GAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPRG 210
OpuAC pfam04069
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity ...
244-505 1.96e-58

Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX), histidine (HisX) and taurine (TauA).


Pssm-ID: 397954 [Multi-domain]  Cd Length: 257  Bit Score: 194.08  E-value: 1.96e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIEQDtDLTVEVTAGvgGGTSNIQPAMESGQFDIYP-EYTGTGWNAVLKrdtqysenlfd 322
Cdd:pfam04069   3 IVIGSKNWTEQEILANIAAQLLEAL-GYVVELVGL--GSSAVLFAALASGDIDLYPeEWTGTTYEAYKK----------- 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 323 elqrAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGY------SGLQRVYG 396
Cdd:pfam04069  69 ----AVEEKLGLLVLGPLGAGNTYGLAVPKYVAEKPGIKSISDLAKPADDLELGFKGEFIGRPDGWgcmrstEGLLKAYG 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 397 MD-----FKDTKDMDiGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPS-YVCGNVVRIDVLKKHPELESVL 470
Cdd:pfam04069 145 LDkyelvEGSEAAMD-ALIYAAYKRGEPDVVYAWTPDWMIKKYDLVVLEDPKGLFPPaYNVVPVVRKGFAEKHPEVAAFL 223
                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2124835902 471 LKLtnTITDQDMSYMNYEVESEGQKPHDVAERYLR 505
Cdd:pfam04069 224 NKL--SLDTEDLNELNAQVDVEGKDPEEVAKDWLA 256
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
20-195 4.19e-23

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 96.58  E-value: 4.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  20 LWEHIGIALLSSIIAIILGLVAGILLNEYRRAV-NPTMMVINFLYTIPSISMLGFLI---------PFSGIGNATAVIAL 89
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLdRLLRRIIDLLLSLPSLVLGLLLVllfgvllgwGILPGLGLPALILA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  90 VIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFIGAG---GLG 166
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGeapGPG 160
                         170       180
                  ....*....|....*....|....*....
gi 2124835902 167 VAIYRGITTNNTTMTVAGSLLIAFLALIM 195
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLS 189
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
24-196 1.31e-21

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 96.31  E-value: 1.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  24 IGIALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGIGNATAVIALVIYALLPMVRNTYT 103
Cdd:PRK10952  150 LALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTIL 229
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 104 GLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFIGAGGLGVAIYRGITTNNTTMTVA 183
Cdd:PRK10952  230 GINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATV 309
                         170
                  ....*....|...
gi 2124835902 184 GSLLIAFLALIMD 196
Cdd:PRK10952  310 GGVGIVILAIILD 322
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
34-204 2.30e-21

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 91.59  E-value: 2.30e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  34 AIILGLVAGILLNeyRRAVNPTMMVINFLYTIPSISMLGFLIPFSGI-----GNATAVIALVIYALLPMVRNTYTGLSSI 108
Cdd:pfam00528   1 GIPLGIIAALRRG--RRLDRLLRPLIDLLQALPSFVLAILLVVIAILsilghGILPAIILALLGWAGYARLIRRAALRSL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 109 DKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFIGAG-GLGV----AIYRGITTNNTTMTVA 183
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLllieAILGYDYPEIQGPVLA 158
                         170       180
                  ....*....|....*....|.
gi 2124835902 184 GSLLIAFLALIMDAVLGFFEK 204
Cdd:pfam00528 159 AALILLLLNLLVDILQRLLDP 179
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
8-198 8.37e-11

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 62.17  E-value: 8.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902   8 LLVENWSFFS---GLLWEHIGIALLSSIIAIILGLVAGIL----LNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGI 80
Cdd:TIGR01097  45 MFPPDWSYLPrilKALLETLAMAILGTVLAAVLAVPLALLaarnITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGL 124
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  81 GNATAVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELP------LAFSVIM--VGIRNMLVMtia 152
Cdd:TIGR01097 125 GPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPqvlpqfLSYTLYRfeINVRAAAVL--- 201
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2124835902 153 ltgvaSFIGAGGLGVAIYRGITTNNTTMTVAGSLLIAFLALIMDAV 198
Cdd:TIGR01097 202 -----GLVGAGGIGLELDTAIGLFDYDEVSAIILVILVVVVIIDLI 242
 
Name Accession Description Interval E-value
PBP2_ProWX cd13612
Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; ...
243-509 0e+00

Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWX of Helicobacter pylori is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270330  Cd Length: 267  Bit Score: 523.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 243 VIHVATKPMTEQLILGDMLKLLIEQDTDLTVEVTAGVGGGTSNIQPAMESGQFDIYPEYTGTGWNAVLKRDTQYSENLFD 322
Cdd:cd13612     1 TIHIATKPMTEQYILGEMLKQLIEQDTDLKVELTKGVGGGTSNIHPAMVKGEFDLYPEYTGTGWLFVLKKDGTYSEELFD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 323 ELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGMDFKDT 402
Cdd:cd13612    81 QLQKEYEEKYNLTWLGLYGFNNTYGLAVRKELAEKYNLKTYSDLAKVSNQLVFGAEYDFFEREDGYDALQKAYGFNFKKT 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 403 KDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITDQDM 482
Cdd:cd13612   161 VDMDIGLKYQAIESGKVDVINVFTTDGQLSDADIVVLEDDKGFFPSYYAGTVVREETLEKYPELEDVLEKLTGLISDEDM 240
                         250       260
                  ....*....|....*....|....*..
gi 2124835902 483 SYMNYEVESEGQKPHDVAERYLRIKGL 509
Cdd:cd13612   241 AEMNYQVEIEKKDPKDVAKEFLEEKGL 267
OsmF COG1732
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system ...
237-505 6.42e-116

Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441338 [Multi-domain]  Cd Length: 294  Bit Score: 343.67  E-value: 6.42e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 237 PSQQSDVIHVATKPMTEQLILGDMLKLLIEqDTDLTVEVTAGVGGgTSNIQPAMESGQFDIYPEYTGTGWNAVLKRDTQY 316
Cdd:COG1732    25 AAAAGDTIVVGSKNFTEQEILAEIYAQALE-AAGLKVERKLNLGG-TEVVRQALKSGEIDLYPEYTGTALTTYLKEDPIT 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 317 S-ENLFDELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVY 395
Cdd:COG1732   103 DpEEVYEAVKEALPEKNGLTWLDPAGFNNTYALAVTKETAEKYGLKTISDLAKVAGELTLGADPEFAERPDGLPGLKKAY 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 396 GMDFKDTKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTN 475
Cdd:COG1732   183 GFEFKEVKPMDTGLTYTALANGQVDVADAYTTDGRIAALDLVVLEDDKNFFPPYNAAPLVRKEVLEKYPELAEVLNKLSG 262
                         250       260       270
                  ....*....|....*....|....*....|
gi 2124835902 476 TITDQDMSYMNYEVESEGQKPHDVAERYLR 505
Cdd:COG1732   263 KLTTETMQELNYQVDVDGEDPADVAREFLK 292
PBP2_osmoprotectants cd13528
Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 ...
244-505 1.42e-113

Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 periplasmic-binding protein fold; This family represents the periplasmic substrate-binding component of ABC transport systems that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270246 [Multi-domain]  Cd Length: 264  Bit Score: 336.49  E-value: 1.42e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIEQDTDLTVEVTAGVGGgTSNIQPAMESGQFDIYPEYTGTGWNAVLKRD--TQYSENLF 321
Cdd:cd13528     2 IVVGSKNFTEQYILGEMLAQLLEANTDLTVERKLNLGG-TEVAFNALKNGDIDLYVEYTGTALLTILKEDapITDPEEVY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 322 DELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGMDFKD 401
Cdd:cd13528    81 EKVKKEYEEKFGLTWLDPLGFNNTYALAVRKDTAEKYGLKTISDLAPHSDQLVFGADPEFYERSDGLPGLKKTYGFDFKE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 402 TKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITDQD 481
Cdd:cd13528   161 VKTMDPGLTYEALDNGEVDVIDAFSTDGRIKAFDLVVLEDDKNFFPPYNAAPVVREDVLKKHPELEEVLNKLSGKLTDET 240
                         250       260
                  ....*....|....*....|....
gi 2124835902 482 MSYMNYEVESEGQKPHDVAERYLR 505
Cdd:cd13528   241 MQQLNYQVDVEGKDPEEVARDFLK 264
PBP2_Opu_like_1 cd13609
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 ...
243-505 1.10e-96

Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270327  Cd Length: 263  Bit Score: 293.35  E-value: 1.10e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 243 VIHVATKPMTEQLILGDMLKLLIEQDTDLTVEVTAGVGGgTSNIQPAMESGQFDIYPEYTGTGWNAVLKR-DTQYSENLF 321
Cdd:cd13609     1 TIVIGSKNFTEQLILGNMYADLIEANTDIKVERKLNLGG-SSVCFSALKNGDIDMYVDYTGTILVNILKEpPISDPDEVY 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 322 DELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGMDFKD 401
Cdd:cd13609    80 NTVKELMKEKYNLEVLKPLGFNNTYTLAVRKETAEKYNLKTISDLAKVSDELTLGCTLEFLNREDGLPGLEKTYGLNFKD 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 402 TKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITDQD 481
Cdd:cd13609   160 VKGLDGSLRYTALENGEVDVIDAFSTDGLLKKFDLVVLEDDKNFFPPYYAVPLVREETLEKYPELEDVLNKLAGKISEET 239
                         250       260
                  ....*....|....*....|....
gi 2124835902 482 MSYMNYEVESEGQKPHDVAERYLR 505
Cdd:cd13609   240 MRELNYKVDELGKDPEDVAHEFLV 263
PBP2_QAT_like cd13614
Substrate-binding domain of quaternary amine ABC-type transporter; the type 2 ...
243-505 1.43e-86

Substrate-binding domain of quaternary amine ABC-type transporter; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative quaternary amine ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270332  Cd Length: 264  Bit Score: 267.33  E-value: 1.43e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 243 VIHVATKPMTEQLILGDMLKLLIEqDTDLTVEVTAGvGGGTSNIQPAMESGQFDIYPEYTGTGWNAVLKRDTQYS-ENLF 321
Cdd:cd13614     1 AIRVGSKNFTEQFILGEMYALALE-DAGIKVERKLN-LGGTLIAHQALVNGEIDLYPEYTGTALLTVLKGEPSSDaKQVY 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 322 DELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGM-DFK 400
Cdd:cd13614    79 KTVKDAYAEQFQLTWLEPAPFNNTYALVMTRETAEKYGIKTLSDLAKAAGELVFGGGPEFQDREDGLPGLKAKYGAfDFK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 401 DTKDMD-IGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITD 479
Cdd:cd13614   159 EFVQVDpLGLRYQALAQGQIDVAVGFGTDGQIAAYGLVVLEDDKNLFPPYQVAPVVRQDVLDANPKIAEVLNKLSALLDN 238
                         250       260
                  ....*....|....*....|....*.
gi 2124835902 480 QDMSYMNYEVESEGQKPHDVAERYLR 505
Cdd:cd13614   239 ETMQRLNYEVDGNKREPKDVAREFLK 264
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
1-210 1.35e-85

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 262.68  E-value: 1.35e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902   1 MIQNIYHLLVENWSFFSGLLWEHIGIALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGI 80
Cdd:COG1174     1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  81 GNATAVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFI 160
Cdd:COG1174    81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2124835902 161 GAGGLGVAIYRGITTNNTTMTVAGSLLIAFLALIMDAVLGFFEKIILYRG 210
Cdd:COG1174   161 GAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPRG 210
PBP2_OpuCC_like cd13608
Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; ...
244-505 2.06e-82

Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; the type 2 periplasmic-binding protein fold; This subfamily includes the periplasmic substrate-binding protein OpuCC of the ABC transporter OpuC (where Opu is osmoprotectant uptake), which can recognize a broad spectrum of compatible solutes, and its paralog OpuBC that can solely bind choline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270326  Cd Length: 265  Bit Score: 256.78  E-value: 2.06e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIEQDTDLTVEVTAGVGGGTSNIQpAMESGQFDI-YPEYTGTGWNAVLKRDTQYS-ENLF 321
Cdd:cd13608     2 IRIGSQSTTESQILAEMVKQLIEHYTDLKVELINNLGSSTVQHQ-AMLNGDANIsAARYTGTDLTGELGMEPIKDpEKAL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 322 DELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQ-DGYSGLQRVYGMDFK 400
Cdd:cd13608    81 KVVQKEFQKRFDQTWFDSYGFANTYAFMVTKEFAEKYNLKKVSDLKKVADNLKLGVDTSWLNRKgDGYPGFKETYGFDFG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 401 DTKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITDQ 480
Cdd:cd13608   161 TVYPMQIGLVYDAVASGKMDVVLGYSTDGRIKSYDLVVLEDDKQFFPPYDASPVATNEILKKYPELEEILEKLEGKISTE 240
                         250       260
                  ....*....|....*....|....*
gi 2124835902 481 DMSYMNYEVESEGQKPHDVAERYLR 505
Cdd:cd13608   241 TMQELNYQVDNDLKEPSVVAKEFLE 265
PBP2_Opu_like_2 cd13613
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 ...
244-504 1.65e-81

Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270331  Cd Length: 264  Bit Score: 254.19  E-value: 1.65e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIEQDTDLTVEVTAGVGGgTSNIQPAMESGQFDIYPEYTGTGWNAVLKRDTQYS-ENLFD 322
Cdd:cd13613     2 IIIGSKNFTEQVILGELLAQQIEARTDLKVERRFNLGG-TFICHQALLSGAIDAYVEYTGTALTAILKQPPIRDpQRVYE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 323 ELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGMDF-KD 401
Cdd:cd13613    81 QVKQLYADRFGLEVMPPLGFENTFAILVRGEDARKLGLKTLSDAAPYTPGWRAGFGYEFLERADGYPGLAKTYGLKFaKT 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 402 TKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITDQD 481
Cdd:cd13613   161 PRVMDLGLLYRALAQKQVDLIAGNSTDGLIAALDLVILEDDRHYFPPYQAVPVVRQATLAKYPELRTAIAELAGKISAET 240
                         250       260
                  ....*....|....*....|...
gi 2124835902 482 MSYMNYEVESEGQKPHDVAERYL 504
Cdd:cd13613   241 MQQMNYQVDGEHRDVAEVAREFL 263
PBP2_AfProX_like cd13607
Substrate-binding protein ProX of ABC-type osmoregulatory transporter from Archaeoglobus ...
244-505 6.68e-72

Substrate-binding protein ProX of ABC-type osmoregulatory transporter from Archaeoglobus fulgidus and its related proteins; the type 2 periplasmic-binding protein fold; This subfamily includes the periplasmic substrate-binding protein ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus and its related proteins. AfProX is involved in uptake of compatible solutes such as the trimethylammonium compound glycine betaine and the dimethylammonium compound proline betaine, but the relative substrate preference is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. AfProX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270325  Cd Length: 261  Bit Score: 229.39  E-value: 6.68e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIEqDTDLTVEVTAGVGGGTSNIQpAMESGQFDIYPEYTGTGWNAVLKR-DTQYSENLFD 322
Cdd:cd13607     2 VVIGSKTFTEQYILAEMIAQLLE-EAGYPAEHREGLGGTRVLFE-ALKSGEIDVYVEYTGTLYAEILKRpETWDPAAVLA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 323 ELQRA-YEDTyqfkwVGMY---GFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGMD 398
Cdd:cd13607    80 ELKEAlAERG-----IVVAgplGFENTYALAMREDRAEALGIRTISDLLARAPDLRFGFDPEFLDRPDGWPALRRVYGLP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 399 FKDTKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTIT 478
Cdd:cd13607   155 FKEVRGLDHTLAYRALKSGQVDVIDAYTTDARIDAYDLRVLEDDRGAFPPYDAVLLYRADLAERAPKAVAALRRLEGRID 234
                         250       260
                  ....*....|....*....|....*..
gi 2124835902 479 DQDMSYMNYEVESEGQKPHDVAERYLR 505
Cdd:cd13607   235 ADTMRALNAQVDLEKRSEAEVAAEFLA 261
PBP2_ChoS cd13610
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; ...
244-504 1.45e-68

Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270328  Cd Length: 264  Bit Score: 220.93  E-value: 1.45e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIEQDT-DLTVEVTAGVGGgTSNIQPAMESGQFDIYPEYTGTGWNAVLKRDTQYSEN--L 320
Cdd:cd13610     2 IVIAGKLGSEPDILINMYKLLIEEETpDLQVTLKPNFGK-TSFLFNALKSGDIDIYPEFTGTVLETLLKEPPKSNDPmeV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 321 FDELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGMDFK 400
Cdd:cd13610    81 YEQARDGLAKQYQLTYLKPMAYNNTYALAVKKEFAKQHNLKTISDLQKVQDKLKAGFTLEFMDREDGYKGLQKAYGLNFN 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 401 dTKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITDQ 480
Cdd:cd13610   161 -VKSMEPALRYQAINNGQVNVIDAYSTDSEIKQYDLVVLKDDKHLFPPYQGAPLMREEFLKKHPELVKALNKLAGKITDE 239
                         250       260
                  ....*....|....*....|....
gi 2124835902 481 DMSYMNYEVESEGQKPHDVAERYL 504
Cdd:cd13610   240 EMQEMNYRVDVKHKSAAKVAKEYL 263
PBP2_YehZ cd13611
Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 ...
244-505 1.25e-67

Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein YehZ of Clostridium sticklandii is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. YehZ belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270329  Cd Length: 267  Bit Score: 218.61  E-value: 1.25e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIeQDTDLTVEVTAGVGGgTSNIQPAMESGQFDIYPEYTGTGWNAVLKRDtqysENLFDE 323
Cdd:cd13611     2 ITVGSKDFTEQLILGKITVQAL-QAAGADVTDKTNLGG-SASARQALENGQVDVYWEYTGTAWITYLGHT----EPILDP 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 324 lQRAYEDTYQ------FKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVS---SQLILGGEYDFFGRQDGYSGLQRV 394
Cdd:cd13611    76 -QEQYEAVKDldaekgLVWLDPAPLNNTYALAMREATAEELGITTLSDLALAKlppGDRTFCVDAEFASRPDGLPPLLEA 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 395 YGMDF--KDTKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLK 472
Cdd:cd13611   155 YGFEFprANVRQMDTGLVYTATANGQCDFGEVFTTDGRIKALDLVVLEDDKGFFPAYNAAPVVRTEVLDAHPELAEILNP 234
                         250       260       270
                  ....*....|....*....|....*....|...
gi 2124835902 473 LTNTITDQDMSYMNYEVESEGQKPHDVAERYLR 505
Cdd:cd13611   235 ISAKLDNDTMQELNARVDVDGEDPADVARDWLV 267
PBP2_ProWY cd13615
Substrate-binding domain of ABC-type osmoregulated transporter; the type 2 periplasmic-binding ...
244-504 1.81e-66

Substrate-binding domain of ABC-type osmoregulated transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWY of Streptococcus thermophilus is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWY belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270333  Cd Length: 262  Bit Score: 215.38  E-value: 1.81e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIEqDTDLTVEVTAGVGGgtSNIQPAMESGQFDIYPEYTGTGWNAVLKRDTQY-SENLFD 322
Cdd:cd13615     2 IRVGSKDFTENLIVAEIYALALE-DAGYKVKRKPNISS--SVVHQALTSGQIDLYPEYTGTGLLAVLKKEAITdPQKVYA 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 323 ELQRAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYG-MDFKD 401
Cdd:cd13615    79 TVKDGYAKKFNLVWLDYAPANDGQGLVIRTSVAKKYGIKTISDLQKNASQIRFASQGEFDQREDGLPGLEKVYGkFSFKS 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 402 TKDMDIGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKKHPELESVLLKLTNTITDQD 481
Cdd:cd13615   159 TKVYDNGLKYQVLANDKADITPAYTTEGQLDTSKFTLLKDDKHVWPPYNLAPVVRKDVLKANPKIASALNKVSAKLTTKT 238
                         250       260
                  ....*....|....*....|...
gi 2124835902 482 MSYMNYEVESEGQKPHDVAERYL 504
Cdd:cd13615   239 LTQLNAKVDVDKQEYADVAKDFY 261
OpuAC pfam04069
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity ...
244-505 1.96e-58

Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX), histidine (HisX) and taurine (TauA).


Pssm-ID: 397954 [Multi-domain]  Cd Length: 257  Bit Score: 194.08  E-value: 1.96e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIEQDtDLTVEVTAGvgGGTSNIQPAMESGQFDIYP-EYTGTGWNAVLKrdtqysenlfd 322
Cdd:pfam04069   3 IVIGSKNWTEQEILANIAAQLLEAL-GYVVELVGL--GSSAVLFAALASGDIDLYPeEWTGTTYEAYKK----------- 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 323 elqrAYEDTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGY------SGLQRVYG 396
Cdd:pfam04069  69 ----AVEEKLGLLVLGPLGAGNTYGLAVPKYVAEKPGIKSISDLAKPADDLELGFKGEFIGRPDGWgcmrstEGLLKAYG 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 397 MD-----FKDTKDMDiGLKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPS-YVCGNVVRIDVLKKHPELESVL 470
Cdd:pfam04069 145 LDkyelvEGSEAAMD-ALIYAAYKRGEPDVVYAWTPDWMIKKYDLVVLEDPKGLFPPaYNVVPVVRKGFAEKHPEVAAFL 223
                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2124835902 471 LKLtnTITDQDMSYMNYEVESEGQKPHDVAERYLR 505
Cdd:pfam04069 224 NKL--SLDTEDLNELNAQVDVEGKDPEEVAKDWLA 256
PBP2_OsmF cd13616
Substrate-binding domain OsmF of an osmoregulated ABC-type transporter; the type 2 ...
244-504 2.34e-44

Substrate-binding domain OsmF of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein OsmF of an ABC transporter (YehZYXW) from Escherichia coli is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. OsmF belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270334  Cd Length: 274  Bit Score: 157.49  E-value: 2.34e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 244 IHVATKPMTEQLILGDMLKLLIEqdtDLTVEVTAGVG-GGTSNIQPAMESGQFDIYPEYTGTGwnAVLKRDTqySENLFD 322
Cdd:cd13616     2 VVVGSKIDTEGALLGNMIVLALE---AHGFPVEDKTGlGTTPVVRKALLSGEIDLYPEYTGNG--AFFFPEA--DDPVWK 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 323 ELQRAYE-------DTYQFKWVGMYGFNNTYGMAVRKDIANKYNLKTYSDLAR-VSS--QLILGGEYDFFGRQDGYSGLQ 392
Cdd:cd13616    75 DARKGYEtvkeldaKNNGLVWLDPAPANNTWAIAVRRDLAEKNNLKTLADLAAyVNEggAFKLAASAEFVERPDALPAFE 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 393 RVYGmdFKDTKDMDI----GLKYQAIE------SGhVDAMPIFTTDGQLSHASIVVLEDDKHLYPSYVCGNVVRIDVLKK 462
Cdd:cd13616   155 KAYG--FKLSKDQLVilsgGNTAQTEQaaaqgtSG-VNAAMAYGTDGAIAALGLVVLEDPKGAQPVYAPAPVVRQEVLEA 231
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2124835902 463 HPELESVLLKLTNTITDQDMSYMNYEVESEGQKPHDVAERYL 504
Cdd:cd13616   232 YPEIAEILKPVFATLDLKTLQELNARIAVEGESAEDVARDYL 273
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
15-209 3.03e-38

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 140.28  E-value: 3.03e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  15 FFSGLLWEHIGI----ALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGIGNATAVIALV 90
Cdd:COG0600    54 LASGELWEHLLAsllrVLLGFALAALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIF 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  91 IYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRnmLVMTIALTG--VASFIGAG-GLGV 167
Cdd:COG0600   134 LGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLR--IALGLAWIGlvVAELLGASsGLGY 211
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2124835902 168 AIYRGITTNNTTMTVAGSLLIAFLALIMDAVLGFFEKIILYR 209
Cdd:COG0600   212 LILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLLERRLLRW 253
PBP2_ProX_like cd13606
Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related ...
252-505 1.34e-34

Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; This group includes periplasmic substrate-binding component of ABC transport systems from gram-negative and -positive bacteria that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270324  Cd Length: 260  Bit Score: 130.76  E-value: 1.34e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 252 TEQLILGDMLKLLIEqDTDLTVEVTAGVGGGTSNIqPAMESGQFDIYPEYTGTGWNAVLKRDTQYS-ENLFDELQRA--- 327
Cdd:cd13606    10 PESEILAEIYAQALE-AAGVKVTRKLNIGSREVYL-PALEDGSIDLVPEYTGNLLQYLDKDATATDpEEVYAALKAAlpe 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 328 ---------YEDTyqfkwvgmygfnNTYgmAVRKDIANKYNLKTYSDLARVSSQLILGGEYDFFGRQDGYSGLQRVYGMD 398
Cdd:cd13606    88 glevldpspAEDK------------DAL--VVTKETAEKYGLKSIADLAPVAGELTLGGPPEFKTRPYGLPGLKEVYGVT 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 399 FKDTKDMDIG--LKYQAIESGHVDAMPIFTTDGQLSHASIVVLEDDKHLYPSyvcGNVV---RIDVLkkHPELESVLLKL 473
Cdd:cd13606   154 FKEFKPLDAGgpLTVKALKDGTVQVANIFTTDPAIADNGLVVLEDPKNLFPA---QNVVplvRKAKL--DDKAADALNAV 228
                         250       260       270
                  ....*....|....*....|....*....|..
gi 2124835902 474 TNTITDQDMSYMNYEVESEGQKPHDVAERYLR 505
Cdd:cd13606   229 SAKLTTEDLTELNKQVVGDKADPADVAKEWLK 260
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
20-195 4.19e-23

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 96.58  E-value: 4.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  20 LWEHIGIALLSSIIAIILGLVAGILLNEYRRAV-NPTMMVINFLYTIPSISMLGFLI---------PFSGIGNATAVIAL 89
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLdRLLRRIIDLLLSLPSLVLGLLLVllfgvllgwGILPGLGLPALILA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  90 VIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFIGAG---GLG 166
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGeapGPG 160
                         170       180
                  ....*....|....*....|....*....
gi 2124835902 167 VAIYRGITTNNTTMTVAGSLLIAFLALIM 195
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLS 189
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
24-196 1.31e-21

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 96.31  E-value: 1.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  24 IGIALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGIGNATAVIALVIYALLPMVRNTYT 103
Cdd:PRK10952  150 LALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTIL 229
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 104 GLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFIGAGGLGVAIYRGITTNNTTMTVA 183
Cdd:PRK10952  230 GINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATV 309
                         170
                  ....*....|...
gi 2124835902 184 GSLLIAFLALIMD 196
Cdd:PRK10952  310 GGVGIVILAIILD 322
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
34-204 2.30e-21

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 91.59  E-value: 2.30e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  34 AIILGLVAGILLNeyRRAVNPTMMVINFLYTIPSISMLGFLIPFSGI-----GNATAVIALVIYALLPMVRNTYTGLSSI 108
Cdd:pfam00528   1 GIPLGIIAALRRG--RRLDRLLRPLIDLLQALPSFVLAILLVVIAILsilghGILPAIILALLGWAGYARLIRRAALRSL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 109 DKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFIGAG-GLGV----AIYRGITTNNTTMTVA 183
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLllieAILGYDYPEIQGPVLA 158
                         170       180
                  ....*....|....*....|.
gi 2124835902 184 GSLLIAFLALIMDAVLGFFEK 204
Cdd:pfam00528 159 AALILLLLNLLVDILQRLLDP 179
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
24-202 1.09e-19

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 88.63  E-value: 1.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  24 IGIALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFL-YTIPSISM-LGFLIPFSGIGNA----TAVIALVIYALLPM 97
Cdd:COG1177    67 LLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLpLVVPGIVLgVALLLLFSALGLSgglwGLILAHVVFTLPFV 146
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  98 VRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIrnMLVMTIAL--TGVASFIGAGG---LGVAIYRG 172
Cdd:COG1177   147 VLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGA--LLAFTLSFdeFVITLFLAGPGvttLPVYIYSM 224
                         170       180       190
                  ....*....|....*....|....*....|
gi 2124835902 173 ITTNNTTMTVAGSLLIAFLALIMDAVLGFF 202
Cdd:COG1177   225 IRRGISPEINALSTLLILLSLLLLLLAERL 254
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
11-194 3.10e-19

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 86.26  E-value: 3.10e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  11 ENWSFFSGLLWEHIG----IALLSSIIAIILGLVAGILLNEYR-------RAVNPTM-MVINFLYTIPSISMLGFLIPF- 77
Cdd:COG2011     3 TMWSELWPLLLQATGetlyMVGVSTLIAVLLGLPLGVLLVLTRpggllpnPVLYRVLgVIVNIFRSIPFIILLVALIPLt 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  78 -----SGIGNATAVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIA 152
Cdd:COG2011    83 rlivgTSIGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIG 162
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2124835902 153 LTGVASFIGAGGLG-VAIYRGITTNNTT-MTVAGSLLIAFLALI 194
Cdd:COG2011   163 YSAMAGAVGGGGLGdLAIRYGYQRFDTDvMLVTVVILIVLVQII 206
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
15-194 4.43e-18

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 87.14  E-value: 4.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  15 FFSGLLWEHIG----IALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFL-YTIPSISM-LGFLIPFSGIGN----AT 84
Cdd:COG1178   331 LLDPSLLRALLnsllLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLpYAVPGIVLgLGLLLLFNRPLPlllyGT 410
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  85 AVIALVIYAL--LPM-VRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIrnMLVMTIALT--GVASF 159
Cdd:COG1178   411 LAILVLAYVVrfLPFaLRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAA--LLVFVTSMKelSATLL 488
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2124835902 160 IGAGG---LGVAIYRGITTNNTTMTVAGSLLIAFLALI 194
Cdd:COG1178   489 LRPPGfetLAVLIYQLASSGRYGEAAALALLLVLVSLL 526
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
7-204 1.25e-16

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 78.58  E-value: 1.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902   7 HLLVENWSFFSGLLWEHIGIALLSSIIAIILGLVAGILlneyRRAVNPTMMVINFLYT-----IPSISML---GFLIPFS 78
Cdd:COG0765     6 SVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALA----RLSPNPVLRWLATAYVeffrgTPLLVQLffiYFGLPLL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  79 GI---GNATAVIALVIYA---LLPMVRntyTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIA 152
Cdd:COG0765    82 GIdlsPFVAAVIALTLNSaayLAEIVR---AGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLK 158
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2124835902 153 LTGVASFIGAGGLgvaIYRGITTNNTTMTVAGSLLIA-----FLALIMDAVLGFFEK 204
Cdd:COG0765   159 DTSLVSVIGVPEL---TRAAQQIASRTFRPFEVYLVAaliylVLTLPLSLLARRLER 212
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
12-195 1.15e-14

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 73.58  E-value: 1.15e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  12 NWSFFSGL---LWEHIGIALLSSIIAIILGLVAGIL----LNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGIGNAT 84
Cdd:COG3639    42 DWSYLPDLlsaLLETLAIALLGTLLGAVLALPLAFLaarnLAPNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFA 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  85 AVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIM--------VGIRNMLVMtialtgv 156
Cdd:COG3639   122 GVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFLsytlyrfeINIRAATVL------- 194
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2124835902 157 aSFIGAGGLGVAIYRGITTNNttMTVAGSLLIAFLALIM 195
Cdd:COG3639   195 -GLVGAGGIGLLLNEAIRLFQ--YDEVAAILLVILVLVL 230
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
14-195 2.94e-13

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 70.18  E-value: 2.94e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  14 SFFSGLLWEHIGIALLSSIIAIILGLVAGILLNEYRRAVNPTMMvinFLYTIP--------SISMLGFL----------- 74
Cdd:COG1176    63 PLYLKVLLRTLWIALLTTLICLLLGYPIAYFLARAPPRWRNLLL---LLVILPfwtsflvrTYAWIVLLgrngllnslll 139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  75 ------IPFSGIGNATAVIALVIYALLP-MVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIrnML 147
Cdd:COG1176   140 alglidEPLRLLYTEFAVVIGLVYVYLPfMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGS--LL 217
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2124835902 148 VMTIALT--GVASFIGAGG---LGVAIYRGITTNN---TTMTVAGSLLIAFLALIM 195
Cdd:COG1176   218 VFIPALGafVTPALLGGGKvlmIGNLIYQQFLSALnwpLAAALAVVLLLIVLLVLL 273
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
17-207 4.70e-13

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 69.19  E-value: 4.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  17 SGLLWEHIGI----ALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGIGNATAVIALVIY 92
Cdd:PRK11365   55 SGELWQHLAIsswrALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALG 134
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  93 ALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFIGA-GGLGVAIYR 171
Cdd:PRK11365  135 TLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISAnSGIGYLAMN 214
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2124835902 172 GITTNNTTMTVAGSLLIAFLALIMDAVLGFFEKIIL 207
Cdd:PRK11365  215 AREFLQTDVVVVAIILYALLGKLADVSAQLLERLWL 250
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
26-195 5.18e-13

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 68.15  E-value: 5.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  26 IALLSSIIAIILGLVAGILLNEYRRavnPTMMVINFLYTIPSI-------------------------SMLGFLIPFSGI 80
Cdd:COG4149    15 VALIATLLLLLLGIPLAWWLARTRF---RGKGLLEALVTLPLVlpptvlgfyllllfgrngplgqlleELFGISLVFTWT 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  81 GnatAVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGirnmLVMTIALT----GV 156
Cdd:COG4149    92 G---AVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAG----AVLAFARAlgefGA 164
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2124835902 157 ASFIgAGG-------LGVAIYRGITTNNTTMT---VAGSLLIAFLALIM 195
Cdd:COG4149   165 TLMF-AGNipgktqtLPLAIYDAVEAGDYAAAhalSLILLAISFVVLLL 212
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
15-195 1.01e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 70.19  E-value: 1.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  15 FFSGLLWEHIG----IALLSSIIAIILGLVAGILLNEY----RRAVNpTMMVINFLytIPS-------ISMLG------- 72
Cdd:COG1178    47 LSDPYLWRALGntllLALLVTLLSLLLGVPLAWLLARTdfpgRRLLR-WLLLLPLA--LPPyvvalawIALFGpngllnt 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  73 FLIPFSGIGNAT------AVIALVIYaLLPMV-RNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIrn 145
Cdd:COG1178   124 LLRALFGLEPPDiyglggIILVLVLF-NYPYVyLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGA-- 200
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2124835902 146 MLVMTIALT--GVASFIGAGG--LGVAIYRGITT--NNTTMTVAGSLLIAFLALIM 195
Cdd:COG1178   201 LLVFLLCLAdfGTPLVLGGGYttLTTAIYQAWLGdfDLGAAAALALVLLLLVLLLL 256
PRK10160 PRK10160
taurine ABC transporter permease TauC;
15-196 1.83e-11

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 64.81  E-value: 1.83e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  15 FFSGLLWEHIGIAL----LSSIIAIILGLVAGILLneyrrAVNPTMM-----VINFLYTIPSISMLGFLIPFSGIGNATA 85
Cdd:PRK10160   71 FMDATLWQHLAASLtrivLALLAAVVIGIPVGIAM-----GLSPTVRgildpLIELYRPVPPLAYLPLMVIWFGIGETSK 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  86 V--IALVIYAllPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFIGAG 163
Cdd:PRK10160  146 IllIYLAIFA--PVAMSALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAAT 223
                         170       180       190
                  ....*....|....*....|....*....|....
gi 2124835902 164 -GLGVAIYRGITTNNTTMTVAGSLLIAFLALIMD 196
Cdd:PRK10160  224 rGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLE 257
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
8-198 8.37e-11

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 62.17  E-value: 8.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902   8 LLVENWSFFS---GLLWEHIGIALLSSIIAIILGLVAGIL----LNEYRRAVNPTMMVINFLYTIPSISMLGFLIPFSGI 80
Cdd:TIGR01097  45 MFPPDWSYLPrilKALLETLAMAILGTVLAAVLAVPLALLaarnITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGL 124
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  81 GNATAVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELP------LAFSVIM--VGIRNMLVMtia 152
Cdd:TIGR01097 125 GPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPqvlpqfLSYTLYRfeINVRAAAVL--- 201
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2124835902 153 ltgvaSFIGAGGLGVAIYRGITTNNTTMTVAGSLLIAFLALIMDAV 198
Cdd:TIGR01097 202 -----GLVGAGGIGLELDTAIGLFDYDEVSAIILVILVVVVIIDLI 242
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
24-194 1.98e-10

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 61.30  E-value: 1.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  24 IGIALLSSIIAIILGLVAGILLNEY----RRAVN---------PTMmVINFLYTI---------PSISMLGFLIPFSGIG 81
Cdd:COG0555    60 LGTALIAALINLVFGLPLAWVLVRYrfpgKRLVDalvdlpfalPTA-VAGIALLLlfgpngwlgQLLAPLGIKVAFTPLG 138
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  82 natAVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIrnmlVMTIALT----GVA 157
Cdd:COG0555   139 ---IVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGF----ALAFARAlgefGAV 211
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2124835902 158 SFIgAGG-------LGVAIYRGITTNNTTMTVAGS---LLIAFLALI 194
Cdd:COG0555   212 IFI-AGNlpmkteiLPLLIYLKLEEGDYAGATAIAlvlLLISFLLLL 257
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
13-194 2.17e-09

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 57.44  E-value: 2.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  13 WSFFSGLlWEHIGIALLSSIIAIILGLVAGILLN--------EYRRAVNPTMMVINFLYTIPSISMLGFLIPF------S 78
Cdd:PRK10782    7 WLLVRGV-WETLAMTFVSGFFGFVIGLPVGVLLYvtrpgqiiANAKLYRTLSALVNIFRSIPFIILLVWMIPFtrvivgT 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  79 GIGNATAVIALVIYALLPMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVAS 158
Cdd:PRK10782   86 SIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGG 165
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2124835902 159 FIGAGGLGVAIYR--GITTNNTTMTVAGSLLIAFLALI 194
Cdd:PRK10782  166 AVGAGGLGQIGYQygYIGYNATVMNTVLVLLVILVYLI 203
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
16-193 5.80e-09

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 57.32  E-value: 5.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  16 FSGLLWEHIGIALLSSIIAIILGLVAGILLneyrrAVNP---TMMVINFLYTIpsISMLGFLIPFS--------GIGNAT 84
Cdd:PRK15050   71 FRGALLTTLQIAFASTAGCLVLGVLLALVL-----AFVPfpgASLVGRFIDTF--VAFPSFLITLAftflygsaGSVNIA 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  85 A-------------------VIALVIYALLPMV-RNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIR 144
Cdd:PRK15050  144 LqrlfgleappldflyspggVILAEITFYTPFVvRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAGGS 223
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2124835902 145 NMLVMTIALTGVASFIGAGG---LGVAIY-RGITTNNTTMTVAGSLLIAFLAL 193
Cdd:PRK15050  224 LCLLLTLNEFGIVLFTGAKDvvtLPVLIYsKAIVDFDYPTACAIAVVNLALSL 276
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
6-142 1.06e-07

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 53.06  E-value: 1.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902   6 YHLLVENWSFFSGLlWEHIGIALLSSIIAIILGLVAGILLNEYRRAVNPTMMVINFLYTI-PSISM-LGFLIPFSGIGNA 83
Cdd:PRK09500   46 YELLFNNDSLLQAA-QHSLTMAVFSATFATLIGSLTAVALYRYRFRGKKFVSGMLFVVMMsPDIVMaISLLVLFMLLGIQ 124
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2124835902  84 TAVIALVIYAL---LPMVRNT-YTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVG 142
Cdd:PRK09500  125 LGFWSLLFAHItfcLPFVVVTvYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAG 187
YnjC COG4135
ABC-type uncharacterized transport system YnjBCD, permease component [General function ...
13-141 8.48e-07

ABC-type uncharacterized transport system YnjBCD, permease component [General function prediction only];


Pssm-ID: 443310 [Multi-domain]  Cd Length: 564  Bit Score: 51.41  E-value: 8.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  13 WSFFSGLLWEHIGIALLSSIIAIILGLVAgiLLNEYRRAVNPTMMVINFLYT---IPSISML-GFLIPFSGIGNATAVIA 88
Cdd:COG4135   351 APGLLEPLGNTLLLALASALIALVLVLAC--LEAEARRGRRPGRRALWLLYLpllVPQIAFLfGLQVLLLRLGLDGTWLA 428
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2124835902  89 LVIYAL---LPmvrntYTGLS------SIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMV 141
Cdd:COG4135   429 VIWAHLvfvLP-----YVFLSlagpwrALDPRYAQVAASLGASPWRVFWRVKLPLLLRPILT 485
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
26-195 8.57e-07

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 50.52  E-value: 8.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  26 IALLSSIIAIILGLVAGILLNEYRRAVN--------PTM-------MVINFLYTiPSISMLGFLIPFSGIGN-------A 83
Cdd:COG1175    84 FTVVSVPLQLVLGLLLALLLNRKLRGRGffrtlfflPWVispvvvaLIWKWLFN-PDYGLLNALLGALGLEPinwlgdpS 162
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  84 TAVIALVIYAL-----LPMVrNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPL-----AFSVIMVGIRNMLVMTI-- 151
Cdd:COG1175   163 LALPAVIIVTVwkgtgFNML-IFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLlrptiLFVLVLSTIGALQVFDLvy 241
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2124835902 152 ALTGvasfigaGG-------LGVAIYR-GITTNNTTMTVAGSLLIAFLALIM 195
Cdd:COG1175   242 VLTG-------GGpgnstttLVLYIYQtAFQQFDFGYASAIAVVLFLIILVL 286
cysT CHL00187
sulfate transport protein; Provisional
11-143 7.08e-06

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 47.32  E-value: 7.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  11 ENWSFFSGLLWEHIGI---------ALLSSIIAIILGLVAGILLNEYR--------RAVN-----PTMMVINFLYTIPSI 68
Cdd:CHL00187   39 QPWSDFLQKATEPIALsaysltlsmALIAALINGFFGLLIAWVLVRYNfpgkrlldAAVDlpfalPTSVAGLTLATVYGD 118
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  69 --------SMLGFLIPFSGIGNATAVIalviYALLP-MVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVI 139
Cdd:CHL00187  119 ngwighllSHLGIQIVFTKLGVLLAMI----FVSFPfVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPAL 194

                  ....
gi 2124835902 140 MVGI 143
Cdd:CHL00187  195 LTGL 198
TauA COG0715
ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion ...
271-466 1.90e-05

ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion transport and metabolism];


Pssm-ID: 440479 [Multi-domain]  Cd Length: 297  Bit Score: 46.54  E-value: 1.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 271 LTVEVTAGVGGgtSNIQPAMESGQFDIypeyTGTGWNAVLkrdtqysenlfdelqRAYEDTYQFKWVGMYGFNNTYGMAV 350
Cdd:COG0715    51 LDVELVEFAGG--AAALEALAAGQADF----GVAGAPPAL---------------AARAKGAPVKAVAALSQSGGNALVV 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 351 RKDiankYNLKTYSDLA--RVSSQLILGGEYdffgrqdgysGLQRV---YGMDFKDTK--DMDIGLKYQAIESGHVDAMP 423
Cdd:COG0715   110 RKD----SGIKSLADLKgkKVAVPGGSTSHY----------LLRALlakAGLDPKDVEivNLPPPDAVAALLAGQVDAAV 175
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2124835902 424 IFTTDGQ--LSHASIVVLEDDKHLYPSYVCGN-VVRIDVLKKHPEL 466
Cdd:COG0715   176 VWEPFESqaEKKGGGRVLADSADLVPGYPGDVlVASEDFLEENPEA 221
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
26-189 2.43e-04

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 42.83  E-value: 2.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  26 IALLSSIIAIILGLVAGILLNEYR-RAVNPTMMVINFLYTIPSI-SMLGFLIPFSGIGNATAVIALV-IYA--LLPMvrN 100
Cdd:COG3833    81 VAVVTAIISVFLAALAAYAFSRFRfKGRKAGLLALLLLQMFPAFlALVALYLLLSALGLLNTLLGLIlVYLggAIPF--N 158
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 101 TYT--G-LSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVgirnmlvmtialTGVASFIGAGG------------- 164
Cdd:COG3833   159 TWLmkGyFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAV------------VALLSFIGPWNdfilasvllrspe 226
                         170       180       190
                  ....*....|....*....|....*....|.
gi 2124835902 165 ---LGVAIYRGIT---TNNTTMTVAGSLLIA 189
Cdd:COG3833   227 nytLAVGLYSFVSdqrNTNWGVFAAGAVLVA 257
PRK15111 PRK15111
peptide ABC transporter permease SapC;
26-151 5.99e-04

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 42.00  E-value: 5.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  26 IALLSSIIAIILGLVAGiLLNEYRRAVnpTMMVINFLYTIPSISMLGFLIPFSGIGNATAVIAlVIYALLP-MVRNTYTG 104
Cdd:PRK15111  105 VTLAATLCGLVLGVFAG-ATHGLRSAV--LNHILDTLLSIPSLLLAIIVVAFAGPSLSHAMFA-VWLALLPrMVRSIYSA 180
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2124835902 105 L-SSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTI 151
Cdd:PRK15111  181 VhDELEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAI 228
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
84-153 7.19e-04

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 41.60  E-value: 7.19e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2124835902  84 TAVIALVIYALLP-MVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIrnMLVMTIAL 153
Cdd:PRK09497  151 SAVIIGLVYILLPfMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGC--LLVLLPAM 219
modB PRK09421
molybdate ABC transporter permease subunit;
21-143 7.48e-04

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 41.06  E-value: 7.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  21 WEHIGIALLSSIIAIILGL---VAGILL--NEYRRAVnptmmVINFLYtipsiSMLGFLIPFSGIGnatAVIALVIYALL 95
Cdd:PRK09421   39 CRFPGKSLLDSLLHLPLVLppvVTGYLLliSMGRRGF-----IGQWLY-----EWFGISFAFSWRG---AALAAAVMAFP 105
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2124835902  96 PMVRNTYTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGI 143
Cdd:PRK09421  106 LMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGT 153
UgpB COG1653
ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport ...
237-373 1.18e-03

ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport and metabolism];


Pssm-ID: 441259 [Multi-domain]  Cd Length: 363  Bit Score: 41.18  E-value: 1.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 237 PSQQSDVIHVATKPMTEQLILGDMLKLLIEQDTDLTVEVT-AGVGGGTSNIQPAMESGQ-FDIY-------PEYTGTGW- 306
Cdd:COG1653    28 AAAGKVTLTVWHTGGGEAAALEALIKEFEAEHPGIKVEVEsVPYDDYRTKLLTALAAGNaPDVVqvdsgwlAEFAAAGAl 107
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2124835902 307 ---NAVLKRDTQYSENLFDELQRAYedTYQFKWVGMYGFNNTYGMAVRKDIANKYNL---KTYSDLARVSSQL 373
Cdd:COG1653   108 vplDDLLDDDGLDKDDFLPGALDAG--TYDGKLYGVPFNTDTLGLYYNKDLFEKAGLdppKTWDELLAAAKKL 178
COG4986 COG4986
ABC-type anion transport system, duplicated permease component [Inorganic ion transport and ...
102-162 1.70e-03

ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism];


Pssm-ID: 444010 [Multi-domain]  Cd Length: 576  Bit Score: 40.98  E-value: 1.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902 102 YTGLSSIDKEMIEAATSLGLSRAQRLRYIELPLAfsviMVG-IRNMLV-------------------MTIALTGVASFIG 161
Cdd:COG4986   153 YQSLRTVPRDLDEAARIFRLSGWQRFWRLELPFA----MPGlVWNSMMsmsggwfflvaseaisvgnQDIRLPGIGSYLA 228

                  .
gi 2124835902 162 A 162
Cdd:COG4986   229 L 229
PRK15100 PRK15100
cystine ABC transporter permease;
25-203 7.34e-03

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 38.19  E-value: 7.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  25 GIALLSSIIAIILGLVAGILLNEYR----RAVN-PTMMVINFLYTIPSISMLgFLI----PFSGIGNATAVIALVIYALl 95
Cdd:PRK15100   20 GYTLQLSIGGMFFGLLLGFILALMRlspiWPVRwLARFYVSIFRGTPLIAQL-FMIyyglPQFGIELDPIPAAMIGLSL- 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124835902  96 pmvrNT--YTG------LSSIDKEMIEAATSLGLSRAQRLRYIELPLAFSVIMVGIRNMLVMTIALTGVASFIGAGGLgv 167
Cdd:PRK15100   98 ----NTaaYAAetlraaISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATIQVPEL-- 171
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2124835902 168 aiYR--GITTNNT----TMTVAGSLLIAFLALIMDAVLGFFE 203
Cdd:PRK15100  172 --FRqaQLITSRTlevfTMYLAASLIYWIMATVLSALQNRFE 211
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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