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Conserved domains on  [gi|2155110619|ref|WP_229810586|]
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LuxR C-terminal-related transcriptional regulator [Actinomadura citrea]

Protein Classification

ATP-binding protein( domain architecture ID 10008120)

ATP-binding protein similar to Mycobacterium tuberculosis uncharacterized protein Mb0918

CATH:  3.40.50.300
Gene Ontology:  GO:0005524
PubMed:  15381417
SCOP:  2000039

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3903 COG3903
Predicted ATPase [General function prediction only];
3-799 7.97e-91

Predicted ATPase [General function prediction only];


:

Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 306.94  E-value: 7.97e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619   3 TNLPAEPNAFVGRERDAADLGRLLEGMRAVTLCGAGGIGKTRLALHVAHavldapRAADAHDGGVWFVELADVRpdgTTG 82
Cdd:COG3903   150 PPPAPLAALARRAAALAAAARALLSAARLVTLTGPGGVGKTRLALEVAH------RLADRFPDGVWFVDLAGVT---DPA 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  83 PVARRVAAVLDVAEEDGRPLTETLADALRAPAVLLVLDNCEHVVEECAKLTGLLLARCPRLRILATSREPLRMAGENVWR 162
Cdd:COG3903   221 LVLAAVARALGVRDAPGRDPAARLRAALADRRLLLVLDNCEHVVDAAAALVRPLLPAAPGLRVLATSREPLGLPGERVLP 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 163 VPPL---------EPGEAVRLFLERARAARPGFAASE----AVHEVTRALDGMPLAVELAAARVRVLSAEQIARRLADRF 229
Cdd:COG3903   301 LPPLavpppgaeaLASEAVALFVERAGAARPGFALDAaeaaAVAEICRRLDGLPLAIELAAARLRTLSLAELAARLDDRL 380

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 230 RLLSAGDRTAPARQRTLRAAIDWSHELLDGPERVLLRRLSVFAG-WTLEQAEHVCADPassdpapsgaalPADDVLDALT 308
Cdd:COG3903   381 RLLTGGRRDAPPRHRTLRAALDWSYDLLSPAERRLLRRLSVFPGgFTLEAAEAVCGGD------------GPADVLDLLA 448

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 309 ALVDKSLATVTGeAGGEVRFRLLDSIREYAAERLAGAGEEAVFRGRHRDAVLADAERDGRIGLGVEPAPWadrvalFHRY 388
Cdd:COG3903   449 ALVDKSLLEVEG-GGGGPRYRLLETVREYAAERLAEAGERAAARRRHADYYLALAERAAAELRGPDQLAW------LARL 521

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 389 DTELGNVEAALTWSLDHGDIAEGLRLCTALRTFWIARGRVAEWADRTDRFLSAARDPGRRgldprvlgpALAGRAQLAMG 468
Cdd:COG3903   522 DAEHDNLRAALRWALAHGDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAGEAAAA---------LAAAAALAAAA 592

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 469 GRDFAQAARHADEALVLCREAGNEFMTATALITGAECLARAGRFTDAARRLDEADALVRGPGREWTRAYACAARGYLLIR 548
Cdd:COG3903   593 AAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAA 672

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 549 ESRLREARERLDTAAAVMRDIGQLWGASHAMIGLGRLAELRGDPAAARGHYAAVLPILTEIGARPEMARALAGLGRVALA 628
Cdd:COG3903   673 AAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAA 752

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 629 RGDLASARASLAESLALSRSSGIRLDMARALDAFAELVASEGDARGAVRLAGAASALREATGREPGAGARRERTLEPIRR 708
Cdd:COG3903   753 AAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAA 832

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 709 RIGEPLVAQYWGEGRAMPADEAIAHALRAPETVPPPRRPVSDAPVKDVAEPVTPPSGLTAREREIARLVSRGLSNRGIAD 788
Cdd:COG3903   833 ALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAA 912

                         810
                  ....*....|.
gi 2155110619 789 ELVISPATVAR 799
Cdd:COG3903   913 AAAALAAAAAA 923
 
Name Accession Description Interval E-value
COG3903 COG3903
Predicted ATPase [General function prediction only];
3-799 7.97e-91

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 306.94  E-value: 7.97e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619   3 TNLPAEPNAFVGRERDAADLGRLLEGMRAVTLCGAGGIGKTRLALHVAHavldapRAADAHDGGVWFVELADVRpdgTTG 82
Cdd:COG3903   150 PPPAPLAALARRAAALAAAARALLSAARLVTLTGPGGVGKTRLALEVAH------RLADRFPDGVWFVDLAGVT---DPA 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  83 PVARRVAAVLDVAEEDGRPLTETLADALRAPAVLLVLDNCEHVVEECAKLTGLLLARCPRLRILATSREPLRMAGENVWR 162
Cdd:COG3903   221 LVLAAVARALGVRDAPGRDPAARLRAALADRRLLLVLDNCEHVVDAAAALVRPLLPAAPGLRVLATSREPLGLPGERVLP 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 163 VPPL---------EPGEAVRLFLERARAARPGFAASE----AVHEVTRALDGMPLAVELAAARVRVLSAEQIARRLADRF 229
Cdd:COG3903   301 LPPLavpppgaeaLASEAVALFVERAGAARPGFALDAaeaaAVAEICRRLDGLPLAIELAAARLRTLSLAELAARLDDRL 380

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 230 RLLSAGDRTAPARQRTLRAAIDWSHELLDGPERVLLRRLSVFAG-WTLEQAEHVCADPassdpapsgaalPADDVLDALT 308
Cdd:COG3903   381 RLLTGGRRDAPPRHRTLRAALDWSYDLLSPAERRLLRRLSVFPGgFTLEAAEAVCGGD------------GPADVLDLLA 448

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 309 ALVDKSLATVTGeAGGEVRFRLLDSIREYAAERLAGAGEEAVFRGRHRDAVLADAERDGRIGLGVEPAPWadrvalFHRY 388
Cdd:COG3903   449 ALVDKSLLEVEG-GGGGPRYRLLETVREYAAERLAEAGERAAARRRHADYYLALAERAAAELRGPDQLAW------LARL 521

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 389 DTELGNVEAALTWSLDHGDIAEGLRLCTALRTFWIARGRVAEWADRTDRFLSAARDPGRRgldprvlgpALAGRAQLAMG 468
Cdd:COG3903   522 DAEHDNLRAALRWALAHGDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAGEAAAA---------LAAAAALAAAA 592

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 469 GRDFAQAARHADEALVLCREAGNEFMTATALITGAECLARAGRFTDAARRLDEADALVRGPGREWTRAYACAARGYLLIR 548
Cdd:COG3903   593 AAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAA 672

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 549 ESRLREARERLDTAAAVMRDIGQLWGASHAMIGLGRLAELRGDPAAARGHYAAVLPILTEIGARPEMARALAGLGRVALA 628
Cdd:COG3903   673 AAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAA 752

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 629 RGDLASARASLAESLALSRSSGIRLDMARALDAFAELVASEGDARGAVRLAGAASALREATGREPGAGARRERTLEPIRR 708
Cdd:COG3903   753 AAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAA 832

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 709 RIGEPLVAQYWGEGRAMPADEAIAHALRAPETVPPPRRPVSDAPVKDVAEPVTPPSGLTAREREIARLVSRGLSNRGIAD 788
Cdd:COG3903   833 ALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAA 912

                         810
                  ....*....|.
gi 2155110619 789 ELVISPATVAR 799
Cdd:COG3903   913 AAAALAAAAAA 923
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 763-820 7.03e-19

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 81.03  E-value: 7.03e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2155110619  763 PSGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWA 820
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
GerE pfam00196
Bacterial regulatory proteins, luxR family;
766-820 7.50e-15

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 69.54  E-value: 7.50e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2155110619 766 LTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWA 820
Cdd:pfam00196   3 LSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 766-822 2.60e-14

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 67.94  E-value: 2.60e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2155110619 766 LTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWAVD 822
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYAIR 57
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 764-823 9.80e-13

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 68.13  E-value: 9.80e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 764 SGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWAVDN 823
Cdd:PRK10651  154 NQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQE 213
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 5-211 8.18e-06

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 49.53  E-value: 8.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619   5 LPAEPNAFVGRERDAADL-GRLLEGMRAV---TLCGAGGIGKTRLALHVAHavldapRAADAHDgGVWFV---------- 70
Cdd:NF040586    1 VPPRNPNFTGREELLERLrDQLRSGGAAVvpqALHGLGGVGKTQLALEYAH------RFRADYD-LVWWIpadqpelvra 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  71 ---ELADVRPDGT-TGPVARRVAAVLdvaeedgrpltetlaDALRAPAV----LLVLDNcehvVEECAKLTGlLLARCPR 142
Cdd:NF040586   74 slaELARRLGLPLgPDDVDEAARAVL---------------DALRRGEPyrrwLLVFDN----ADDPEDLRD-LLPTGGP 133

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 143 LRILATSREPL-RMAGENVWRVPPLEPGEAVRLFLERAraarPGFAASEAVHEVTRALDGMPLAVELAAA 211
Cdd:NF040586  134 GHVLITSRNRAwSEVAAATLEVDVFSREESVALLRRRV----PGLTSEEDADRLAEALGDLPLALEQAAA 199
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
 766-808 6.79e-05

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 44.09  E-value: 6.79e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2155110619 766 LTAREREIARLvSR--GLSNRGIADELVISPATVARHVTNILTKL 808
Cdd:TIGR02985 114 LPEQCREIFIL-SRfeGLSNKEIAEELGISVKTVEYHITKALKFL 157
 
Name Accession Description Interval E-value
COG3903 COG3903
Predicted ATPase [General function prediction only];
3-799 7.97e-91

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 306.94  E-value: 7.97e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619   3 TNLPAEPNAFVGRERDAADLGRLLEGMRAVTLCGAGGIGKTRLALHVAHavldapRAADAHDGGVWFVELADVRpdgTTG 82
Cdd:COG3903   150 PPPAPLAALARRAAALAAAARALLSAARLVTLTGPGGVGKTRLALEVAH------RLADRFPDGVWFVDLAGVT---DPA 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  83 PVARRVAAVLDVAEEDGRPLTETLADALRAPAVLLVLDNCEHVVEECAKLTGLLLARCPRLRILATSREPLRMAGENVWR 162
Cdd:COG3903   221 LVLAAVARALGVRDAPGRDPAARLRAALADRRLLLVLDNCEHVVDAAAALVRPLLPAAPGLRVLATSREPLGLPGERVLP 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 163 VPPL---------EPGEAVRLFLERARAARPGFAASE----AVHEVTRALDGMPLAVELAAARVRVLSAEQIARRLADRF 229
Cdd:COG3903   301 LPPLavpppgaeaLASEAVALFVERAGAARPGFALDAaeaaAVAEICRRLDGLPLAIELAAARLRTLSLAELAARLDDRL 380

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 230 RLLSAGDRTAPARQRTLRAAIDWSHELLDGPERVLLRRLSVFAG-WTLEQAEHVCADPassdpapsgaalPADDVLDALT 308
Cdd:COG3903   381 RLLTGGRRDAPPRHRTLRAALDWSYDLLSPAERRLLRRLSVFPGgFTLEAAEAVCGGD------------GPADVLDLLA 448

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 309 ALVDKSLATVTGeAGGEVRFRLLDSIREYAAERLAGAGEEAVFRGRHRDAVLADAERDGRIGLGVEPAPWadrvalFHRY 388
Cdd:COG3903   449 ALVDKSLLEVEG-GGGGPRYRLLETVREYAAERLAEAGERAAARRRHADYYLALAERAAAELRGPDQLAW------LARL 521

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 389 DTELGNVEAALTWSLDHGDIAEGLRLCTALRTFWIARGRVAEWADRTDRFLSAARDPGRRgldprvlgpALAGRAQLAMG 468
Cdd:COG3903   522 DAEHDNLRAALRWALAHGDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAGEAAAA---------LAAAAALAAAA 592

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 469 GRDFAQAARHADEALVLCREAGNEFMTATALITGAECLARAGRFTDAARRLDEADALVRGPGREWTRAYACAARGYLLIR 548
Cdd:COG3903   593 AAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAA 672

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 549 ESRLREARERLDTAAAVMRDIGQLWGASHAMIGLGRLAELRGDPAAARGHYAAVLPILTEIGARPEMARALAGLGRVALA 628
Cdd:COG3903   673 AAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAA 752

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 629 RGDLASARASLAESLALSRSSGIRLDMARALDAFAELVASEGDARGAVRLAGAASALREATGREPGAGARRERTLEPIRR 708
Cdd:COG3903   753 AAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAA 832

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 709 RIGEPLVAQYWGEGRAMPADEAIAHALRAPETVPPPRRPVSDAPVKDVAEPVTPPSGLTAREREIARLVSRGLSNRGIAD 788
Cdd:COG3903   833 ALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAA 912

                         810
                  ....*....|.
gi 2155110619 789 ELVISPATVAR 799
Cdd:COG3903   913 AAAALAAAAAA 923
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 763-820 7.03e-19

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 81.03  E-value: 7.03e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2155110619  763 PSGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWA 820
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 766-823 3.37e-18

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 81.48  E-value: 3.37e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2155110619 766 LTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWAVDN 823
Cdd:COG2197    70 LTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELVLLALRL 127
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 760-821 7.45e-18

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 78.46  E-value: 7.45e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2155110619 760 VTPPSGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWAV 821
Cdd:COG5905     7 TSHPSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWAL 68
GerE pfam00196
Bacterial regulatory proteins, luxR family;
766-820 7.50e-15

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 69.54  E-value: 7.50e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2155110619 766 LTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWA 820
Cdd:pfam00196   3 LSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 766-822 2.60e-14

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 67.94  E-value: 2.60e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2155110619 766 LTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWAVD 822
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYAIR 57
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 764-823 9.80e-13

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 68.13  E-value: 9.80e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 764 SGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWAVDN 823
Cdd:PRK10651  154 NQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQE 213
PRK15369 PRK15369
two component system response regulator;
761-820 4.06e-09

two component system response regulator;


Pssm-ID: 185267 [Multi-domain]  Cd Length: 211  Bit Score: 57.40  E-value: 4.06e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 761 TPPSGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWA 820
Cdd:PRK15369  145 TNPPLLTPRERQILKLITEGYTNRDIAEQLSISIKTVETHRLNMMRKLDVHKVAELLNWA 204
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 766-821 6.53e-09

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 56.65  E-value: 6.53e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2155110619 766 LTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWAV 821
Cdd:COG4566   138 LTPREREVLDLVVAGLSNKQIARELGISPRTVEVHRANVMEKLGARSLAELVRLAL 193
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
656-821 3.42e-08

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 54.38  E-value: 3.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 656 ARALDAFAELVASEGDARGAVRLAGAASALREATGREPGAGARRERTLEPIRRRIGEPLVAQYWGEGRAMPADEAIAHAL 735
Cdd:COG2771    20 LLALLLLLLLAALLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLLLLALLLLLALLALLAALLA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 736 RAPETVPPPRRPVSDAPvkDVAEPVTPPSGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQ 815
Cdd:COG2771   100 RLAALLLALALAALLLA--ALARLLARAPGLTPREREVLRLLAEGLTLKEIARILGISERTVRTHLKRIYRKLGVSSRAE 177


                  ....*.
gi 2155110619 816 IAAWAV 821
Cdd:COG2771   178 LVALAL 183
COG3903 COG3903
Predicted ATPase [General function prediction only];
161-560 4.81e-07

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 53.48  E-value: 4.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 161 WRVPPLEPGEAVRLFLERARAARPGFAASEAVHEVTRALDGMPLAVELAAARVRVLSAEQIARRLADRFRLLSAGDRTAP 240
Cdd:COG3903   534 WALAHGDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAA 613

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 241 ARQRTLRAAIDWSHELLDGPERVLLRRLSVFAGWTLEQAEHVCADPASSDPAPSGAALPADDVLDALTALVDKSLATVTG 320
Cdd:COG3903   614 AAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAA 693

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 321 EAGGEVRFRLLDSIREYAAERLAGAGEEAVFRGRHRDAVLADAERDGRIGLGVEPAPWADRVALFHRYDTELGNVEAALT 400
Cdd:COG3903   694 LAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALA 773

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 401 WSLDHGDIAEGLRLCTALRTFWIARGRVAEWADRTDRFLSAARDPGRRGLDPRVLGPALAGRAQLAMGGRDFAQAARHAD 480
Cdd:COG3903   774 ALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAA 853

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 481 EALVLCREAGNEFMTATALITGAECLARAGRFTDAARRLDEADALVRGPGREWTRAYACAARGYLLIRESRLREARERLD 560
Cdd:COG3903   854 LAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAAAAAAAAA 933
PRK10360 PRK10360
transcriptional regulator UhpA;
766-817 1.31e-06

transcriptional regulator UhpA;


Pssm-ID: 182408 [Multi-domain]  Cd Length: 196  Bit Score: 49.59  E-value: 1.31e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2155110619 766 LTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIA 817
Cdd:PRK10360  138 LTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLMEKLGVSNDVELA 189
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
768-820 1.42e-06

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 49.32  E-value: 1.42e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2155110619 768 AREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWA 820
Cdd:COG2909   125 ALAALRRRLLAEGLSNKEIAERLFISVNTVKTHLRNIYRKLGVRSRTEAVARA 177
PRK10100 PRK10100
transcriptional regulator CsgD;
766-824 1.46e-06

transcriptional regulator CsgD;


Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 49.87  E-value: 1.46e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2155110619 766 LTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWAVDNI 824
Cdd:PRK10100  156 LTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNL 214
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 503-695 1.54e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.50  E-value: 1.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 503 AECLARAGRFTDAARRLDEADALVRGpgrewtRAYACAARGYLLIRESRLREARERLDTAAAVMRDigqlwgASHAMIGL 582
Cdd:COG2956    83 AQDYLKAGLLDRAEELLEKLLELDPD------DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPE------NAHAYCEL 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 583 GRLAELRGDPAAARGHYAAVLpilteiGARPEMARALAGLGRVALARGDLASARASLAESLALSRssgirlDMARALDAF 662
Cdd:COG2956   151 AELYLEQGDYDEAIEALEKAL------KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDP------DYLPALPRL 218

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2155110619 663 AELVASEGDargavrLAGAASALREATGREPGA 695
Cdd:COG2956   219 AELYEKLGD------PEEALELLRKALELDPSD 245
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 5-211 8.18e-06

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 49.53  E-value: 8.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619   5 LPAEPNAFVGRERDAADL-GRLLEGMRAV---TLCGAGGIGKTRLALHVAHavldapRAADAHDgGVWFV---------- 70
Cdd:NF040586    1 VPPRNPNFTGREELLERLrDQLRSGGAAVvpqALHGLGGVGKTQLALEYAH------RFRADYD-LVWWIpadqpelvra 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  71 ---ELADVRPDGT-TGPVARRVAAVLdvaeedgrpltetlaDALRAPAV----LLVLDNcehvVEECAKLTGlLLARCPR 142
Cdd:NF040586   74 slaELARRLGLPLgPDDVDEAARAVL---------------DALRRGEPyrrwLLVFDN----ADDPEDLRD-LLPTGGP 133

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 143 LRILATSREPL-RMAGENVWRVPPLEPGEAVRLFLERAraarPGFAASEAVHEVTRALDGMPLAVELAAA 211
Cdd:NF040586  134 GHVLITSRNRAwSEVAAATLEVDVFSREESVALLRRRV----PGLTSEEDADRLAEALGDLPLALEQAAA 199
PRK09935 PRK09935
fimbriae biosynthesis transcriptional regulator FimZ;
766-820 8.26e-06

fimbriae biosynthesis transcriptional regulator FimZ;


Pssm-ID: 182154 [Multi-domain]  Cd Length: 210  Bit Score: 47.56  E-value: 8.26e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2155110619 766 LTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWA 820
Cdd:PRK09935  150 LSNREVTILRYLVSGLSNKEIADQLLLSNKTVSAHKSNIYGKLGLHSIVELIDYA 204
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 458-679 8.39e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.19  E-value: 8.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 458 ALAGRAQLAMGGRDFAQAARHADEALVLCREAgnefmtATALITGAECLARAGRFTDAARRLDEADALVRGPgrewtrAY 537
Cdd:COG2956    78 ALLELAQDYLKAGLLDRAEELLEKLLELDPDD------AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN------AH 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 538 ACAARGYLLIRESRLREARERLDTAAAVMRDigqlwgASHAMIGLGRLAELRGDPAAARGHYAAVLPIlteigaRPEMAR 617
Cdd:COG2956   146 AYCELAELYLEQGDYDEAIEALEKALKLDPD------CARALLLLAELYLEQGDYEEAIAALERALEQ------DPDYLP 213

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2155110619 618 ALAGLGRVALARGDLASARASLAESLALSRSSgirldmaRALDAFAELVASEGDARGAVRLA 679
Cdd:COG2956   214 ALPRLAELYEKLGDPEEALELLRKALELDPSD-------DLLLALADLLERKEGLEAALALL 268
COG3899 COG3899
Predicted ATPase [General function prediction only];
427-821 1.23e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 49.09  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  427 RVAEWADRTDRFLSAARDPGRRGLDPRVLGPALAGRAQLAMGgrDFAQAARHADEALVLCREAGNEFMTATALITGAECL 506
Cdd:COG3899    763 EAEALLERALAARALAALAALRHGNPPASARAYANLGLLLLG--DYEEAYEFGELALALAERLGDRRLEARALFNLGFIL 840

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  507 ARAGRFTDAARRLDEADALVRGPGrEWTRAYACAARGYLLIRESRLREARERLDTAAAVMRDIGQLWGASHAMIGLGRLA 586
Cdd:COG3899    841 HWLGPLREALELLREALEAGLETG-DAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELA 919

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  587 ELRGDPAAARGHYAAVLPILTEIGARPEMARALAGLGRVALARGDLASARASLAESLALSRSSGIRLDMARALDAFAELV 666
Cdd:COG3899    920 RLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALL 999

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  667 ASEGDARGAVRLAGAASALREATGREPGAGARRERTLEPIRRRIGEPLVAQYWGEGRAMPADEAIAHALRAPETVPPPRR 746
Cdd:COG3899   1000 ALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAA 1079

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2155110619  747 PVSDAPVKDVAEPVTPPSGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSRAQIAAWAV 821
Cdd:COG3899   1080 AAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALALAALLLLAA 1154
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 423-645 1.29e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.84  E-value: 1.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 423 IARGRVAEWADRTDRFLSAARDPGRRGLDPRVLGPALAGRAQLAMGGRDFAQAARHADEALVLCREAGNEFMTATALitg 502
Cdd:COG3914    12 LAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLL--- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 503 aeclARAGRFTDAARRLDEAdaLVRGPgrewTRAYACAARGYLLIRESRLREARERLDTAAAVMRDIGQLWgashamIGL 582
Cdd:COG3914    89 ----QALGRYEEALALYRRA--LALNP----DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAY------LNL 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2155110619 583 GRLAELRGDPAAARGHYAAVLPIlteigaRPEMARALAGLGRVALARGDLASARASLAESLAL 645
Cdd:COG3914   153 GEALRRLGRLEEAIAALRRALEL------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALEL 209
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
496-737 4.99e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.77  E-value: 4.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 496 ATALITGAECLARAGRFTDAARRLDEADALVRGPgrewtrAYACAARGYLLIRESRLREARERLDTAAAVMRDIGQLWga 575
Cdd:COG0457     8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDD------AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEAL-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 576 shamIGLGRLAELRGDPAAARGHYAAVLPIlteigaRPEMARALAGLGRVALARGDLASARASLAESLALSRSSGIRL-- 653
Cdd:COG0457    80 ----NNLGLALQALGRYEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALyn 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 654 ---------DMARALDAFAELVASEGDARGAVRLAGAASALREATGREPGAGARRERTLEPIRRRIGEPLVAQYWGEGRA 724
Cdd:COG0457   150 lgialeklgRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALAL 229

                         250
                  ....*....|...
gi 2155110619 725 MPADEAIAHALRA 737
Cdd:COG0457   230 LLALRLAALALYQ 242
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
 766-808 6.79e-05

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 44.09  E-value: 6.79e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2155110619 766 LTAREREIARLvSR--GLSNRGIADELVISPATVARHVTNILTKL 808
Cdd:TIGR02985 114 LPEQCREIFIL-SRfeGLSNKEIAEELGISVKTVEYHITKALKFL 157
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
458-708 9.33e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.00  E-value: 9.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 458 ALAGRAQLAMGGRDFAQAARHADEALVLCREagnefmTATALITGAECLARAGRFTDAARRLDEADALvrgpgrEWTRAY 537
Cdd:COG0457    10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPD------DAEALYNLGLAYLRLGRYEEALADYEQALEL------DPDDAE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 538 ACAARGYLLIRESRLREARERLDTAAAVMRDIGQLWgashamIGLGRLAELRGDPAAARGHYAAVLPIlteigaRPEMAR 617
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEAL------YNLGLALLELGRYDEAIEAYERALEL------DPDDAD 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 618 ALAGLGRVALARGDLASARASLAESLALSRSSGIRLDMARALDAFAELVASEGDARGAVRLAGAASALREATGREPGAGA 697
Cdd:COG0457   146 ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLL 225

                         250
                  ....*....|.
gi 2155110619 698 RRERTLEPIRR 708
Cdd:COG0457   226 ALALLLALRLA 236
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
762-813 1.05e-04

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 44.46  E-value: 1.05e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2155110619 762 PPSGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSR 813
Cdd:PRK10403  150 PFSVLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSR 201
COG3899 COG3899
Predicted ATPase [General function prediction only];
382-737 1.27e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 46.00  E-value: 1.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  382 VALFHRYDTELGNVEAALTWSLDHGDIAEGLRLCTALRTFWIARGRVAEWADRTDRFLSAARDPGRRGLDPRVLGPALAG 461
Cdd:COG3899    800 LLLLGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAA 879

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  462 RAQLAMGGRDFAQAARHADEALVLCREAGNEFMTATALITGAEC--LARAGRFTDAARRLDEADALVRGPGREWTRAYAC 539
Cdd:COG3899    880 AAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAaaAAAAALALAAAAAAAAAAALAAAAAAAALAAALA 959

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  540 AARGYLLIRESRLREARERLDTAAAVMRDIGQLWGASHAMIGLGRLAELRGDPAAARGHYAAVLPILTEIGARPEMARAL 619
Cdd:COG3899    960 LAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAA 1039

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  620 AGLGRVALARGDLASARASLAESLALSRSSGIRLDMARALDAFAELVASEGDARGAVRLAGAASALREATGREPGAGARR 699
Cdd:COG3899   1040 AAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAA 1119

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 2155110619  700 ERTLEPIRRRIGEPLVAQYWGEGRAMPADEAIAHALRA 737
Cdd:COG3899   1120 LAALALAAAARAAAALLLLAAALALALAALLLLAALLL 1157
SPS1 COG0515
Serine/threonine protein kinase [Signal transduction mechanisms];
553-780 1.82e-04

Serine/threonine protein kinase [Signal transduction mechanisms];


Pssm-ID: 440281 [Multi-domain]  Cd Length: 482  Bit Score: 45.00  E-value: 1.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 553 REARERLDTAAAVMRDIGQLW-GASHAMIGLGRLAELRGDPAAARGHYAAVLPILTEIGARPEMARALAGLGRVALARGD 631
Cdd:COG0515   249 KDPEERYQSAAELAAALRAVLrSLAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAA 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 632 LASARASLAESLALSRSSGIRLDMARALDAFAELVASEGDARGAVRLAGAASALREATGREPGAGARRERTLEPIRRRIG 711
Cdd:COG0515   329 AAAAAAALAAAAAAAAAAAAAALLAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAALAAAAAAAA 408

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2155110619 712 EPLVAQYWGEGRAMPADEAIAHALRAPETVPPPRRPVSDAPVKDVAEPVTPPSGLTAREREIARLVSRG 780
Cdd:COG0515   409 AAAAAAAAAAALAAAAAAAAAAAAAAAAAAAAAARLLAAAAAAAAAAAAAPLLAALLAAAALAAAAAAA 477
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
764-813 2.27e-04

HTH-type transcriptional regulator MalT;


Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 44.94  E-value: 2.27e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2155110619 764 SGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKLGFSSR 813
Cdd:PRK04841  837 SPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGIAHR 886
EntF COG1020
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites ...
 80-511 2.70e-04

EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440643 [Multi-domain]  Cd Length: 1329  Bit Score: 44.85  E-value: 2.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619   80 TTGPVARRVAAVLdVAEEDGRPLTETLADALRAPAVLLVLDnCEHVVEECAKLTGLLLARCPRLRILATSREPLRmagen 159
Cdd:COG1020    907 EDAPGDKRLVAYV-VPEAGAAAAAALLRLALALLLPPYMVP-AAVVLLLPLPLTGNGKLDRLALPAPAAAAAAAA----- 979

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  160 vwRVPPLEPGEAVRLFLERARAARPGFAASEAVHEVTRALDGMPLAVELAAARVRVLSAEQIARRLADRFRLLSAGDRTA 239
Cdd:COG1020    980 --AAPPAEEEEEEAALALLLLLVVVVGDDDFFFFGGGLGLLLLLALARAARLLLLLLLLLLLFLAAAAAAAAAAAAAAAA 1057

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  240 PARQRTLRAAIDWSHELLDGPERVLLRRLSVFAGWTLEQAEHVCADPASSDPAPSGAALPADDVLDALTALVDKSLATVT 319
Cdd:COG1020   1058 AAAAPLAAAAAPLPLPPLLLSLLALLLALLLLLALLALLALLLLLLLLLLLLALLLLLALLLALLAALRARRAVRQEGPR 1137

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  320 GEAGGEVRFRLLDSIREYAAERLAGAGEEAVFRGRHRDAVLADAERDGRIGLGVEPAPWADRVALFHRYDTELGNVEAAL 399
Cdd:COG1020   1138 LRLLVALAAALALAALLALLLAAAAAAAELLAAAALLLLLALLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 1217

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  400 TWSLDHGDIAEGLRLCTALRTFWIARGRVAEWADRTDRFLSAARDPGRRGLDPRVLGPALAGRAQLAMGGRDFAQAARHA 479
Cdd:COG1020   1218 LLLLLLLAAAAAALLALALLLALLALAALLALAALAALAAALLALALALLALALLLLALALLLPALARARAARTARALAL 1297

                          410       420       430
                   ....*....|....*....|....*....|..
gi 2155110619  480 DEALVLCREAGNEFMTATALITGAECLARAGR 511
Cdd:COG1020   1298 LLLLALLLLLALALALLLLLLLLLALLLLALL 1329
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 496-646 2.86e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.72  E-value: 2.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 496 ATALITGAECLARAGRFTDAARRLDEADALVRgpgrewTRAYACAARGYLLIRESRLREARERLDTAAAVMRDigqlwgA 575
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELDP------DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD------E 71

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2155110619 576 SHAMIGLGRLAELRGDPAAARGHYAAVLpilteiGARPEMARALAGLGRVALARGDLASARASLAESLALS 646
Cdd:COG4783    72 PEARLNLGLALLKAGDYDEALALLEKAL------KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 547-641 4.28e-04

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 43.92  E-value: 4.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  547 IRESRLR-EARERLDTAAAvMRDIGQLWGASHAM----------IGLGRLAELRGDPAAARGHYAAVLPIlteigaRPEM 615
Cdd:PRK11447   564 IQELAQRlQSDQVLETANR-LRDSGKEAEAEALLrqqppstridLTLADWAQQRGDYAAARAAYQRVLTR------EPGN 636

                           90       100
                   ....*....|....*....|....*.
gi 2155110619  616 ARALAGLGRVALARGDLASARASLAE 641
Cdd:PRK11447   637 ADARLGLIEVDIAQGDLAAARAQLAK 662
TPR_12 pfam13424
Tetratricopeptide repeat;
575-648 7.50e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.91  E-value: 7.50e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2155110619 575 ASHAMIGLGRLAELRGDPAAARGHYAAVLPILTEI--GARPEMARALAGLGRVALARGDLASARASLAESLALSRS 648
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
PRK06930 PRK06930
positive control sigma-like factor; Validated
 689-809 7.59e-04

positive control sigma-like factor; Validated


Pssm-ID: 180757 [Multi-domain]  Cd Length: 170  Bit Score: 41.25  E-value: 7.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 689 TGREPGA--GARRERTLEpiRRRIGEPLVAQ-YWgegRAMPADEAIAHalrapetvpPPRRPVSDAPVKDVAEPVtppSG 765
Cdd:PRK06930   52 KGRQPGNrrGIDRRAAYQ--REVICDPLLIQrYF---RSMEDLEWDIE---------EPESVISEWDKIRIEDAL---SV 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2155110619 766 LTAREREIArLVSR--GLSNRGIADELVISPATVARHVTNILTKLG 809
Cdd:PRK06930  115 LTEREKEVY-LMHRgyGLSYSEIADYLNIKKSTVQSMIERAEKKIA 159
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 456-682 1.55e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 41.53  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 456 GPALAGRAQLAMGGRDFAQAARHADEALVLCREAGNEFMTATALITGAECLARaGRFTDAARRLDEADALVRGPGREWTR 535
Cdd:pfam17874   1 GEIAALRAQLAISKGDAERALELAEQALALLPEDDLLARGLATFVLGEAYLCL-GDLDAALQAMREAEALARRADSPHVT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 536 AYACAARGYLLIRESRLREARERLDTAAAVMRDIG--QLWGASHAMIGLGRLAELRGDPAAARGHYAAVLPILTEIGARP 613
Cdd:pfam17874  80 LWALLQQGEILRAQGRLHQALETYQQALQLARDHGlqHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQWEPDA 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 614 EMArALAGLGRVALARGDLASARASLAESLALSRSSGIRLDM-ARALDAFAELVASEGDARGAVRLAGAA 682
Cdd:pfam17874 160 AVD-AYVLLARIALAQGELEEALTLLRRAELLARQSFFHVDWlANAERVRVRLWLARGDLRAAVRWLRAA 228
fixJ PRK09390
response regulator FixJ; Provisional
 729-812 2.25e-03

response regulator FixJ; Provisional


Pssm-ID: 181815 [Multi-domain]  Cd Length: 202  Bit Score: 39.99  E-value: 2.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 729 EAIAHALRAPetvppPRRPVSDAPVKDVAEPVtppSGLTAREREIARLVSRGLSNRGIADELVISPATVARHVTNILTKL 808
Cdd:PRK09390  113 GAIERALAQA-----PEAAKSEAVAADIRARI---ASLSERERQVMDGLVAGLSNKVIARDLDISPRTVEVYRANVMTKM 184


                  ....
gi 2155110619 809 GFSS 812
Cdd:PRK09390  185 QAGS 188
NACHT COG5635
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
30-784 5.25e-03

Predicted NTPase, NACHT family domain [Signal transduction mechanisms];


Pssm-ID: 444362 [Multi-domain]  Cd Length: 935  Bit Score: 40.56  E-value: 5.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619  30 RAVTLCGAGGIGKTRLALHVAHAVLDapRAADAHDGGVWFVELADVRPDgttgpvARRVAAVLDVAEEDGRPLTETLADA 109
Cdd:COG5635   181 KRLLILGEPGSGKTTLLRYLALELAE--RYLDAEDPIPILIELRDLAEE------ASLEDLLAEALEKRGGEPEDALERL 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 110 LRAPAVLLVLDNCEHVVEECAKLTGL-----LLARCPRLRILATSR----EPLRMAGENVWRVPPLEPgEAVRLFLERAR 180
Cdd:COG5635   253 LRNGRLLLLLDGLDEVPDEADRDEVLnqlrrFLERYPKARVIITSRpegyDSSELEGFEVLELAPLSD-EQIEEFLKKWF 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 181 AARPgfaaseavhevtraldgmplavELAAARVRVLSAEQIARRLADRFRLLS-------AGDRTAPARQRTLRAAIDWS 253
Cdd:COG5635   332 EATE----------------------RKAERLLEALEENPELRELARNPLLLTllalllrERGELPDTRAELYEQFVELL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 254 HELLDGPERV----------LLRRLSVFAGWTLEQAEHVCADPASSD--PAPSGAALPADDVLDALTAlvdkSLATVTGE 321
Cdd:COG5635   390 LERWDEQRGLtiyrelsreeLRELLSELALAMQENGRTEFAREELEEilREYLGRRKDAEALLDELLL----RTGLLVER 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 322 AGGEVRFRLLdSIREY-AAERLAGAGEEavfrgrHRDAVLADAERDGR--------IGLGVEPAPWADRVALFHRYDTEL 392
Cdd:COG5635   466 GEGRYSFAHR-SFQEYlAARALVEELDE------ELLELLAEHLEDPRwrevllllAGLLDDVKQIKELIDALLARDDAA 538

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 393 GNVEAALTWSLDHGDIAEGLRLCTALRTFWIARGRVAEWADRTDRFLSAARDPGRRGLDPRVLGPALAGRAQLAMGGRDF 472
Cdd:COG5635   539 ALALAAALLLALLLALALLALLALLLLLRLLLALLALLLLALLLLLLLALLLALLALDLGLAALLLLLLLLLLLLLLLAL 618

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 473 AQAARHADEALVLCREAGNEFMTATALITGAECLARAGRFTDAARRLDEADALVRGPGREWTRAYACAARGYLLIRESRL 552
Cdd:COG5635   619 ALLLALLLLLLLLLLAELLLLALLALVLLSLLLASRLLLITLLLLAAASAALLLLLLLLLAELLLALLALASLLLLLLLA 698

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 553 REARERLDTAAAVMRDIGQLWGASHAMIGLGRLAELRGDPAAARGHYAAVLPILTEIGARPEMARALAGLGRVALARGDL 632
Cdd:COG5635   699 LALALALLLLAVLLAAALDLLLLLVLLLALLLVLALALSLLLLALALLLAGALLLESSALLAVLLASLLLALLLLSLLLL 778

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155110619 633 ASARASLAESLALSRSSGIRLDMARALDAFAELVASEGDARGAVRLAGAASALREATGREPGAGARRERTLEPIRRRIGE 712
Cdd:COG5635   779 LVLLLALALLASLLLALLLLILLLVLLGSLLLLRLLDDLALLLLLALAAARLLLSSLALVALELARASLGASLVLLALLL 858

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2155110619 713 PLVAQYWGEGRAMPADEAIAHALRAPETVPPPRRPVSDAPVKDVAEPVTPPSGLTAREREIARLVSRGLSNR 784
Cdd:COG5635   859 ATLLLLLLLLLALALALLSLLSLSSLALLSLLGLLLALSLLALLLLSLSLALAALLLAAREALTLDRLLSLA 930
HTH_38 pfam13936
Helix-turn-helix domain; This helix-turn-helix domain is often found in transferases and is ...
 763-801 7.66e-03

Helix-turn-helix domain; This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.


Pssm-ID: 433591 [Multi-domain]  Cd Length: 44  Bit Score: 35.18  E-value: 7.66e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2155110619 763 PSGLTARER-EIARLVSRGLSNRGIADELVISPATVARHV 801
Cdd:pfam13936   2 GKHLSLEEReEIARLLAEGLSLREIARRLGRSPSTISREL 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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