|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
115-323 |
2.11e-58 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 187.81 E-value: 2.11e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 115 NNIAHDLKTPLTRLKNKLENLKQTNPNKDS------SDALAECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDA 188
Cdd:COG2205 21 ANVSHELRTPLTSILGAAELLLDEEDLSPEerrellEIIRESAERLLRLIEDLLDLSRLESGKLSLELEPVDLAELLEEA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 189 IELYEPIFEQKNIRLKINILPRNLNI--DKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNEN 266
Cdd:COG2205 101 VEELRPLAEEKGIRLELDLPPELPLVyaDPELLEQVLANLLDNAIKYSPPGGTITISARREGDGVRISVSDNGPGIPEEE 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2164748496 267 TNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:COG2205 181 LERIFERFYRGDNSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPLA 237
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
1-323 |
5.32e-56 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 184.73 E-value: 5.32e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 1 MAMLFTVLLGLSIVSWIYIIFSAVGDRVIEHIIPLSIGIFCTVSVVIISYLISVFVVRKINHIASSAASIVNTRDFSQRI 80
Cdd:COG0642 1 LLLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 81 KSNTNWDDLSNLANILNILLANIEELLVDIKSVSNNIAHDLKTPLTRLKNKLENLKQTNPNKDSSDA---LAECNQLLDI 157
Cdd:COG0642 81 LLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELDEEQREYLetiLRSADRLLRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 158 FNSLLRLNRLEHGRENLIKKRLDIKNIIDDAIELYEPIFEQKNIRLKINI--LPRNLNIDKNLIFQSIINILDNCYKYSK 235
Cdd:COG0642 161 INDLLDLSRLEAGKLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLpdDLPTVRGDPDRLRQVLLNLLSNAIKYTP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 236 DNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLK 315
Cdd:COG0642 241 EGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSRRGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTT 320
|
....*...
gi 2164748496 316 MIISLPLH 323
Cdd:COG0642 321 FTVTLPLA 328
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
7-322 |
5.89e-55 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 183.60 E-value: 5.89e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 7 VLLGLSIVSWIYIIFSAVGDRVIEHIIPLSIGIFCTVSVVIISYLISVFVVRKINHIASSAASIVNTRDFSQRIKSNTNW 86
Cdd:COG5002 55 LLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 87 DDLSNLANILNILLANIEELLVDIKSVSN-------NIAHDLKTPLTRLKNKLENLkQTNPNKDSSD-------ALAECN 152
Cdd:COG5002 135 SLRLSALLLGLLLLAAVERDITELERLEQmrrefvaNVSHELRTPLTSIRGYLELL-LDGAADDPEErreyleiILEEAE 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 153 QLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDAIELYEPIFEQKNIRLKINILPRNLNI--DKNLIFQSIINILDNC 230
Cdd:COG5002 214 RLSRLVNDLLDLSRLESGELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLVlgDPDRLEQVLTNLLDNA 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 231 YKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQT--GNGLGLSLVKKIIQLHDGDVIAQN 308
Cdd:COG5002 294 IKYTPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSREtgGTGLGLAIVKHIVEAHGGRIWVES 373
|
330
....*....|....
gi 2164748496 309 NKPQGLKMIISLPL 322
Cdd:COG5002 374 EPGKGTTFTITLPL 387
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
117-323 |
1.48e-35 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 133.16 E-value: 1.48e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKQTNPNKDSSDA----------LAECNQLLDIFNSLLRLNRLEhgreNLIKKRLDIKNIID 186
Cdd:COG5000 208 IAHEIKNPLTPIQLSAERLRRKLADKLEEDRedleraldtiIRQVDRLKRIVDEFLDFARLP----EPQLEPVDLNELLR 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 187 DAIELYEPIFEQKNIRLKINILPRNLNI--DKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINN 264
Cdd:COG5000 284 EVLALYEPALKEKDIRLELDLDPDLPEVlaDRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGPGIPE 363
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2164748496 265 ENTNKIFERFFreekSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:COG5000 364 EVLERIFEPFF----TTKPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPLA 418
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
46-306 |
8.73e-35 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 131.74 E-value: 8.73e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 46 VIISYLISVFVVR---KINHIASSAASIVNTRDFSQRIKSNTNWDDLSNLANILNILLANIEELLVDIKSVSNNIAHDLK 122
Cdd:TIGR01386 174 VLLTALLGWWITRlglEPLRRLSAVAARISPESLDQRLDPSRAPAELRELAQSFNAMLGRLEDAFQRLSQFSADLAHELR 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 123 TPLTRLKNKLE-NLKQTNPNKDSSDALA----ECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDAIELYEPIFE 197
Cdd:TIGR01386 254 TPLTNLLGQTQvALSQPRTGEEYREVLEsnleELERLSRMVSDMLFLARADNGQLALERVRLDLAAELAKVAEYFEPLAE 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 198 QKNIRLKINILPRnLNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFRE 277
Cdd:TIGR01386 334 ERGVRIRVEGEGL-VRGDPQMFRRAISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRV 412
|
250 260 270
....*....|....*....|....*....|.
gi 2164748496 278 EKSR--SQTGNGLGLSLVKKIIQLHDGDVIA 306
Cdd:TIGR01386 413 DPARsnSGEGTGLGLAIVRSIMEAHGGRASA 443
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
2-323 |
5.12e-30 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 119.12 E-value: 5.12e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 2 AMLFTVLLGLSIVSWIYIIFSAVGDRVIEHIIPLSIGIFCTVSVVIISYLISVFVVRKINHIASSAASIVNTRDFSQRIK 81
Cdd:COG4251 174 ALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 82 SNTNWDDLSNLANILNILLANIEELLVDIKSVSNNIAHDLKTPLTRLKNKLENLKQTNPNKDSSDAL-------AECNQL 154
Cdd:COG4251 254 LLELRLELEELEEELEERTAELERSNEELEQFAYVASHDLREPLRKISGFSQLLEEDYGDKLDEEGReylerirDAAERM 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 155 LDIFNSLLRLNRLehGRENLIKKRLDIKNIIDDAIELYEPIFEQKNIRLKINILPRnLNIDKNLIFQSIINILDNCYKYS 234
Cdd:COG4251 334 QALIDDLLAYSRV--GRQELEFEPVDLNELLEEVLEDLEPRIEERGAEIEVGPLPT-VRGDPTLLRQVFQNLISNAIKYS 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 235 KDNT--EISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQ 312
Cdd:COG4251 411 RPGEppRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEYEGTGIGLAIVKKIVERHGGRIWVESEPGE 490
|
330
....*....|.
gi 2164748496 313 GLKMIISLPLH 323
Cdd:COG4251 491 GATFYFTLPKA 501
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
75-323 |
2.52e-29 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 116.66 E-value: 2.52e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 75 DFSQRIKSnTNWDDLSNLANILNILLANIEE-------LLVDIksvsnniAHDLKTPLTRLKNKLENL----KQTNPNKD 143
Cdd:PRK10549 206 DFTTRVTP-TSRDELGRLAQDFNQLASTLEKneqmrrdFMADI-------SHELRTPLAVLRGELEAIqdgvRKFTPESV 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 144 SSdALAECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDAIELYEPIFEQKNIRLKINiLPRNLNI--DKNLIFQ 221
Cdd:PRK10549 278 AS-LQAEVGTLTKLVDDLHQLSLSDEGALAYRKTPVDLVPLLEVAGGAFRERFASRGLTLQLS-LPDSATVfgDPDRLMQ 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 222 SIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQT--GNGLGLSLVKKIIQL 299
Cdd:PRK10549 356 LFNNLLENSLRYTDSGGSLHISAEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSRNRAsgGSGLGLAICLNIVEA 435
|
250 260
....*....|....*....|....
gi 2164748496 300 HDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:PRK10549 436 HNGRIIAAHSPFGGVSITVELPLE 459
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
219-320 |
1.91e-28 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 105.76 E-value: 1.91e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 219 IFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQTGNGLGLSLVKKIIQ 298
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSREGGGTGLGLAIVRRIVE 80
|
90 100
....*....|....*....|..
gi 2164748496 299 LHDGDVIAQNNKPQGLKMIISL 320
Cdd:cd00075 81 AHGGRITVESEPGGGTTFTVTL 102
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
214-322 |
6.12e-28 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 104.65 E-value: 6.12e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 214 IDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQT-GNGLGLSL 292
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIgGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|
gi 2164748496 293 VKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLPL 110
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
118-323 |
1.48e-27 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 111.86 E-value: 1.48e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 118 AHDLKTPLTRLKNKLENLKQTNPNKD----SSDALAECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDAIELYE 193
Cdd:PRK11100 264 THELKSPLAAIRGAAELLQEDPPPEDrarfTGNILTQSARLQQLIDRLLELARLEQRQELEVLEPVALAALLEELVEARE 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 194 PIFEQKNIRLKINILPRNLNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFER 273
Cdd:PRK11100 344 AQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPDYALPRIFER 423
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2164748496 274 FF---REEKSRSQTgnGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:PRK11100 424 FYslpRPANGRKST--GLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPRH 474
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
104-302 |
3.22e-27 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 109.66 E-value: 3.22e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 104 EELLVDIKS---VSNNIAHDLKTPLTRLKNKLENLKQTNPNKDSSDALAECNQLLDIFNSLLR-LNR-----LEHGR--- 171
Cdd:PRK09303 142 ETLLEQLKFkdrVLAMLAHDLRTPLTAASLALETLELGQIDEDTELKPALIEQLQDQARRQLEeIERlitdlLEVGRtrw 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 172 ENLI--KKRLDIKNIIDDAIELYEPIFEQKNIRLKINI---LPrNLNIDKNLIFQSIINILDNCYKYSKDNTEISI---- 242
Cdd:PRK09303 222 EALRfnPQKLDLGSLCQEVILELEKRWLAKSLEIQTDIpsdLP-SVYADQERIRQVLLNLLDNAIKYTPEGGTITLsmlh 300
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2164748496 243 --NTKIQnskyiIEIADQGIGINNENTNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDG 302
Cdd:PRK09303 301 rtTQKVQ-----VSICDTGPGIPEEEQERIFEDRVRLPRDEGTEGYGIGLSVCRRIVRVHYG 357
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
117-323 |
4.60e-27 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 108.73 E-value: 4.60e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLK----QTNPNKDSSDALAECNQLL----DIFNSLLRLNRlehgRENLIKKRLDIKNIIDDA 188
Cdd:COG4191 149 IAHEINNPLAAILGNAELLRrrleDEPDPEELREALERILEGAeraaEIVRSLRAFSR----RDEEEREPVDLNELIDEA 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 189 IELYEPIFEQKNIRLKINI---LPRnLNIDKNLIFQSIINILDNcykySKD------NTEISINTKIQNSKYIIEIADQG 259
Cdd:COG4191 225 LELLRPRLKARGIEVELDLppdLPP-VLGDPGQLEQVLLNLLIN----AIDameegeGGRITISTRREGDYVVISVRDNG 299
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2164748496 260 IGINNENTNKIFERFF---REEKsrsqtGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:COG4191 300 PGIPPEVLERIFEPFFttkPVGK-----GTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLPLA 361
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
117-322 |
1.59e-24 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 103.96 E-value: 1.59e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKQTNPNKDSSDALaECNQLLD-------IFNSLLRLNRLEHGRENLIKKRLDIKNIIDDAI 189
Cdd:PRK10490 671 LSHDLRTPLTVLFGQAEILTLDLASEGSPHAR-QASEIRQqvlnttrLVNNLLDMARIQSGGFNLRKEWLTLEEVVGSAL 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 190 ELYEPIFEQKNIRLKiniLPRNL---NIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNEN 266
Cdd:PRK10490 750 QMLEPGLSGHPINLS---LPEPLtliHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGERLQLDVWDNGPGIPPGQ 826
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2164748496 267 TNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:PRK10490 827 EQLIFDKFARGNKESAIPGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLPL 882
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
65-323 |
2.60e-23 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 99.29 E-value: 2.60e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 65 SSAASIVNTRDFSQRiksnTNWDDLSNLANI---LNILLANIEELLVDIKSVSNNIAHDLKTPLTRLKNKLENLKqtNPN 141
Cdd:PRK10604 168 EAAAQRLGDGHLAER----IHFDEGSSLERLgvaFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSD--NLS 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 142 KDSSDALA-ECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDAIELYEPIFEQKNIRLKINILPRNLNIDKNLIF 220
Cdd:PRK10604 242 AAESQALNrDIGQLEALIEELLTYARLDRPQNELHLSEPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGALDMRLME 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 221 QSIINILDNCYKYSKDNTEISIntKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKS--RSQTGNGLGLSLVKKIIQ 298
Cdd:PRK10604 322 RVLDNLLNNALRYAHSRVRVSL--LLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSrdRATGGCGLGLAIVHSIAL 399
|
250 260
....*....|....*....|....*
gi 2164748496 299 LHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:PRK10604 400 AMGGSVNCDESELGGARFSFSWPVW 424
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
96-323 |
4.07e-23 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 99.24 E-value: 4.07e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 96 LNILLANIEELLVDIksvsnniAHDLKTPLTRLKnkLENLKQTNPNKDSSDaLA----ECNQLLDIFNSLLRLNRLEHGR 171
Cdd:PRK09470 236 LERMMTSQQRLLSDI-------SHELRTPLTRLQ--LATALLRRRQGESKE-LErietEAQRLDSMINDLLVLSRNQQKN 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 172 EnLIKKRLDIKNIIDDAIElyEPIFE--QKNIRLKINILPRN--LNIDKNLIFQSIINILDNCYKYSKDntEISINTKIQ 247
Cdd:PRK09470 306 H-LERETFKANSLWSEVLE--DAKFEaeQMGKSLTVSAPPGPwpINGNPNALASALENIVRNALRYSHT--KIEVAFSVD 380
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2164748496 248 NSKYIIEIADQGIGINNENTNKIFERFFR--EEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:PRK09470 381 KDGLTITVDDDGPGVPEEEREQIFRPFYRvdEARDRESGGTGLGLAIVENAIQQHRGWVKAEDSPLGGLRLTIWLPLY 458
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
117-322 |
8.38e-23 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 97.16 E-value: 8.38e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKQTNPNKDSSD----ALAECNQLLDIFNSLLRLNRlehgRENLIKKRLDIKNIIDDAIELY 192
Cdd:COG5807 154 IAHEIRNPLTSIKGFLQLLQESREDSEREEyfniIISEIDRINTIITELLVLSK----PKKFNFKKLNLNDVLEDVIALL 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 193 EPIFEQKNIRLKINILPRN--LNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKI 270
Cdd:COG5807 230 STEAILKNISIKYDLADDEpvINGDKNQLKQVFINLIKNAIEAMETGGNITIKTYVEGDFVVISVKDEGIGIPEEVLEKI 309
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2164748496 271 FERFFreekSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:COG5807 310 GEPFF----TTKEEGTGLGLSICKKIIEEHNGTIEVESKPGKGTTFTIYLPL 357
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
117-322 |
1.44e-21 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 94.21 E-value: 1.44e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKQTNP------NKDssdaLAECNQLLDIFNSLLRlnrleHGREnLIKKRLDIKNIIDDAIE 190
Cdd:PRK09467 236 VSHDLRTPLTRIRLATEMMSEEDGylaesiNKD----IEECNAIIEQFIDYLR-----TGQE-MPMEMADLNALLGEVIA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 191 L---YEpifeqKNIRLKINILPRNLNIDKNLIFQSIINILDNCYKYSkdNTEISINTKiQNSKYI-IEIADQGIGINNEN 266
Cdd:PRK09467 306 AesgYE-----REIETALQPGPIEVPMNPIAIKRALANLVVNAARYG--NGWIKVSSG-TEGKRAwFQVEDDGPGIPPEQ 377
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2164748496 267 TNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:PRK09467 378 LKHLFQPFTRGDSARGSSGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLPL 433
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
46-323 |
1.56e-21 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 94.45 E-value: 1.56e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 46 VIISYLIsVFVVRKINHiaSSAASIvntRDFSQRIKSNTNWD------------DLSNLANILNILLANIEELLVDIKSV 113
Cdd:PRK09835 192 SVISLLI-VFIVLLAVH--KGHAPI---RSVSRQIQNITSKDldvrldpqtvpiELEQLVLSFNHMIERIEDVFTRQSNF 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 114 SNNIAHDLKTPLTRLKNKLE-NLKQTNPNKDSSDA----LAECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDA 188
Cdd:PRK09835 266 SADIAHEIRTPITNLITQTEiALSQSRSQKELEDVlysnLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLDLADEVGKV 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 189 IELYEPIFEQKNIRLKINILPRNLNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTN 268
Cdd:PRK09835 346 FDFFEAWAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEHLP 425
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2164748496 269 KIFERFFREEKSRSQT--GNGLGLSLVKKIIQLHDGDVIAQNNkPQGLKMIISLPLH 323
Cdd:PRK09835 426 RLFDRFYRVDPSRQRKgeGSGIGLAIVKSIVVAHKGTVAVTSD-ARGTRFVISLPRL 481
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
215-322 |
1.72e-21 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 87.42 E-value: 1.72e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 215 DKNLIFQSIINILDNCYKYSKDNTEISINTKiQNSKYIIEIADQGIGINNENTNKIFERFFREEKsRSQTGNGLGLSLVK 294
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKHAAKAGEITVTLS-EGGELTLTVEDNGIGIPPEDLPRIFEPFSTADK-RGGGGTGLGLSIVR 79
|
90 100
....*....|....*....|....*...
gi 2164748496 295 KIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:pfam02518 80 KLVELLGGTITVESEPGGGTTVTLTLPL 107
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
116-323 |
1.76e-21 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 93.37 E-value: 1.76e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 116 NIAHDLKTPLTRLKNKLENLKQTNPNKDSSDAL----AECNQLLDIFNSLLRLNRLEHGRenliKKRLDIKNIIDDAIEL 191
Cdd:COG3852 141 GLAHEIRNPLTGIRGAAQLLERELPDDELREYTqliiEEADRLNNLVDRLLSFSRPRPPE----REPVNLHEVLERVLEL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 192 YEPIFeQKNIRLKINILPR--NLNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYI----------IEIADQG 259
Cdd:COG3852 217 LRAEA-PKNIRIVRDYDPSlpEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRVERQVTLgglrprlyvrIEVIDNG 295
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2164748496 260 IGINNENTNKIFERFFreekSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:COG3852 296 PGIPEEILDRIFEPFF----TTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPLE 355
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
117-323 |
3.10e-21 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 94.26 E-value: 3.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKQTNPNKDSSDALAECNQLLDifnsllRLNR-----LEHGRENLIKKR-LDIKNIIDDAIE 190
Cdd:PRK11360 397 VAHEIRNPLTAIRGYVQIWRQQTSDPPSQEYLSVVLREVD------RLNKvidqlLEFSRPRESQWQpVSLNALVEEVLQ 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 191 LYEPIFEQKNIRLKINiLPRNL---NIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYI-IEIADQGIGINNEN 266
Cdd:PRK11360 471 LFQTAGVQARVDFETE-LDNELppiWADPELLKQVLLNILINAVQAISARGKIRIRTWQYSDGQVaVSIEDNGCGIDPEL 549
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2164748496 267 TNKIFERFFreekSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:PRK11360 550 LKKIFDPFF----TTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLPIN 602
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
219-322 |
1.12e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 85.07 E-value: 1.12e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 219 IFQSIINILDNCYKYSkdNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFR--EEKSRSQTGNGLGLSLVKKI 296
Cdd:cd16949 1 LARALENVLRNALRYS--PSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRvdSARDRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 2164748496 297 IQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLPA 104
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
215-320 |
3.46e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 81.30 E-value: 3.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 215 DKNLIFQSIINILDNCYKYSKDNTEISIntKIQNSKY-IIEIADQGIGINNENTNKIFERFFREEKsRSQTGNGLGLSLV 293
Cdd:cd16940 10 DALLLFLLLRNLVDNAVRYSPQGSRVEI--KLSADDGaVIRVEDNGPGIDEEELEALFERFYRSDG-QNYGGSGLGLSIV 86
|
90 100
....*....|....*....|....*..
gi 2164748496 294 KKIIQLHDGDVIAQNNKPQGLKMIISL 320
Cdd:cd16940 87 KRIVELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
117-322 |
1.77e-17 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 82.86 E-value: 1.77e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKqtnPNKDSSDA-----LAECNQLLDIFNSLLRLNRlehgRENLIKKRLDIKNIIDDAIEL 191
Cdd:COG5805 294 IAHEIRNPLTSIKGFLQLLQ---PGIEDKEEyfdimLSELDRIESIISEFLALAK----PQAVNKEKENINELIQDVVTL 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 192 YEP--IFEQKNIRLKINILPRNLNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNK 269
Cdd:COG5805 367 LETeaILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKK 446
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2164748496 270 IFERFFreekSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:COG5805 447 LGEPFF----TTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPL 495
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
117-323 |
1.60e-16 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 80.02 E-value: 1.60e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKQTNpNKDSSD----ALAECNQLLDIFNSLLRLNRLEHGRENLIkkrlDIKNIIDDAIELY 192
Cdd:COG5809 277 IAHEIRNPLTSLKGFIQLLKDTI-DEEQKTyldiMLSELDRIESIISEFLVLAKPQAIKYEPK----DLNTLIEEVIPLL 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 193 EPIFEQKNIRLKInILPRNLNI---DKNLIFQSIINILDNCYKYSKDNTEISINTKIQ-NSKYIIEIADQGIGINNENTN 268
Cdd:COG5809 352 QPQALLKNVQIEL-ELEDDIPDilgDENQLKQVFINLLKNAIEAMPEGGNITIETKAEdDDKVVISVTDEGCGIPEERLK 430
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2164748496 269 KIFERFFreekSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:COG5809 431 KLGEPFY----TTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPIK 481
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
96-321 |
4.09e-16 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 78.09 E-value: 4.09e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 96 LNILLANIEELLVDIKSVSNNIAHDLKTPLTRLKNKLENLKQTNPnKDSSDALAECNQLLDIFNSLLRLNRLEHGRENLI 175
Cdd:PRK10755 123 LNQLVSRLTSTLDQERLFTADVAHELRTPLAGIRLHLELLEKQHH-IDVAPLIARLDQMMHTVEQLLQLARAGQSFSSGH 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 176 KKRLD-IKNIIDDAIELYEPIFEQKNIRLKINILPRNLNI--DKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYI 252
Cdd:PRK10755 202 YQTVKlLEDVILPSQDELSEMLEQRQQTLLLPESAADITVqgDATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGGAV 281
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 253 IEIADQGIGINNENTNKIFERFFREEKSRSqtGNGLGLSLVKKIIQLHDGDVIAQNNKPQ-GLKMIISLP 321
Cdd:PRK10755 282 LAVEDEGPGIDESKCGELSKAFVRMDSRYG--GIGLGLSIVSRITQLHHGQFFLQNRQERsGTRAWVWLP 349
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
92-313 |
7.72e-16 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 77.77 E-value: 7.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 92 LANILNILLANIEELLVDIKSVSNNIAHDLKTPLTRLKNKLE--NLKQTNPnKDSSDALAECNQLLD----IFNSLLRLN 165
Cdd:PRK10337 219 LVEALNQLFARTHAMMVRERRFTSDAAHELRSPLAALKVQTEvaQLSDDDP-QARKKALLQLHAGIDratrLVDQLLTLS 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 166 RLEHGrENLIK-KRLDIKNIIDDA-IELYEPIfEQKNI--RLKINILPRNLNIDKNLIFQSIINILDNCYKYSKDNTEIS 241
Cdd:PRK10337 298 RLDSL-DNLQDvAEIPLEDLLQSAvMDIYHTA-QQAGIdvRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVD 375
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2164748496 242 INTKIQNskyiIEIADQGIGINNENTNKIFERFFREeKSRSQTGNGLGLSLVKKIIQLHDGDViAQNNKPQG 313
Cdd:PRK10337 376 VTLNARN----FTVRDNGPGVTPEALARIGERFYRP-PGQEATGSGLGLSIVRRIAKLHGMNV-SFGNAPEG 441
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
225-302 |
1.08e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 71.65 E-value: 1.08e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2164748496 225 NILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDG 302
Cdd:cd16923 7 NLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTEGAGLGLSIAKAIIELHGG 84
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
215-321 |
2.06e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 70.95 E-value: 2.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 215 DKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQT--GNGLGLSL 292
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRAsgGSGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 2164748496 293 VKKIIQLHDGDVIAQNNKPQGLKMIISLP 321
Cdd:cd16946 81 CHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
117-322 |
4.80e-15 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 75.93 E-value: 4.80e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKQTNPNKDS-----SDALAECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDAIEL 191
Cdd:PRK09959 719 MSHEIRTPISSIMGFLELLSGSGLSKEQrveaiSLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHS 798
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 192 YEPIFEQKNIRLKIN-ILPRN--LNIDKNLIFQSIINILDNCYKYSKDNTeISINTK---IQNSKYIIE--IADQGIGIN 263
Cdd:PRK09959 799 FGAIAASKSIALSCSsTFPDHylVKIDPQAFKQVLSNLLSNALKFTTEGA-VKITTSlghIDDNHAVIKmtIMDSGSGLS 877
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2164748496 264 NENTNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:PRK09959 878 QEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPV 936
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
117-322 |
1.60e-14 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 73.75 E-value: 1.60e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKQTNPNKDSSD-----ALAECNQLLDIFNSLLRLNRLEHGRenliKKRLDIKNIIDDAIEL 191
Cdd:COG5806 208 IAHEVRNPLTVVRGFIQLLQEPELSDEKRKqyiriALEELDRAEAIITDYLTFAKPQPEK----LEKIDVSEELEHVIDV 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 192 YEPIFEQKNIRLKINILPR-NLNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKI 270
Cdd:COG5806 284 LSPYANMNNVEIQTELEPGlYIEGDRQKLQQCLINIIKNGIEAMPNGGTLTIDVSIDKNKVIISIKDTGVGMTKEQLERL 363
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2164748496 271 FERFFreekSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:COG5806 364 GEPYF----STKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTITLPL 411
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
215-308 |
1.88e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 68.26 E-value: 1.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 215 DKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRS-QTGNGLGLSLV 293
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSgQKSTGLGLAFV 80
|
90
....*....|....*
gi 2164748496 294 KKIIQLHDGDVIAQN 308
Cdd:cd16945 81 QEVAQLHGGRITLRN 95
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
221-322 |
3.08e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 67.90 E-value: 3.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 221 QSIINILDNCYKYSkDNTEISINTKIQNSKY-----IIEIADQGIGINNENTNKIFERFFREEKS--RSQTGNGLGLSLV 293
Cdd:cd16922 3 QILLNLLGNAIKFT-EEGEVTLRVSLEEEEEdgvqlRFSVEDTGIGIPEEQQARLFEPFSQADSSttRKYGGTGLGLAIS 81
|
90 100
....*....|....*....|....*....
gi 2164748496 294 KKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:cd16922 82 KKLVELMGGDISVESEPGQGSTFTFTLPL 110
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
115-322 |
8.64e-14 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 71.98 E-value: 8.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 115 NNIAHDLKTPLTRLKNKLEnLKQTNPNKDSSDALAE----C-NQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDA- 188
Cdd:PRK15347 403 TTISHEIRTPLNGVLGALE-LLQNTPLTAEQMDLADtarqCtLSLLAIINNLLDFSRIESGQMTLSLEETALLPLLDQAm 481
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 189 IELYEPIFEqKNIRLKINI---LPRNLNIDKNLIFQSIINILDNCYKYSKDNtEISINTKIQNSKYIIEIADQGIGINNE 265
Cdd:PRK15347 482 LTIQGPAQS-KSLTLRTFVgahVPLYLHLDSLRLRQILVNLLGNAVKFTETG-GIRLRVKRHEQQLCFTVEDTGCGIDIQ 559
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2164748496 266 NTNKIFERFFREEKSRSqtGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:PRK15347 560 QQQQIFTPFYQADTHSQ--GTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLPL 614
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
216-321 |
1.50e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 65.77 E-value: 1.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 216 KNLIFqsIIN-ILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSR-SQTGNGLGLSLV 293
Cdd:cd16948 4 KWLSF--IIGqIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRnFQESTGMGLYLV 81
|
90 100
....*....|....*....|....*....
gi 2164748496 294 KKII-QLHDGDVIAQNNKpQGLKMIISLP 321
Cdd:cd16948 82 KKLCdKLGHKIDVESEVG-EGTTFTITFP 109
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
223-321 |
1.51e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 65.55 E-value: 1.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 223 IINILDNCYKYSkdNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDG 302
Cdd:cd16950 5 LSNLVDNALRYG--GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARGTSGTGLGLAIVQRISDAHGG 82
|
90
....*....|....*....
gi 2164748496 303 DVIAQNNKPQGLKMIISLP 321
Cdd:cd16950 83 SLTLANRAGGGLCARIELP 101
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
223-321 |
1.78e-13 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 65.59 E-value: 1.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 223 IINILDNCYKYSKDNTEISINTKIQNSKYI-IEIADQGIGINNENTNKIFERFFR--EEKSRSQTGNGLGLSLVKKIIQL 299
Cdd:cd16925 9 VLNLLSNAFKFTPDGGRIRCILEKFRLNRFlLTVSDSGPGIPPNLREEIFERFRQgdGSSTRAHGGTGLGLSIVKEFVEL 88
|
90 100
....*....|....*....|..
gi 2164748496 300 HDGDVIAQNNKPQGLKMIISLP 321
Cdd:cd16925 89 HGGTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
215-318 |
2.00e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 65.56 E-value: 2.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 215 DKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQTGN-GLGLSLV 293
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGHyGMGLYIA 80
|
90 100
....*....|....*....|....*
gi 2164748496 294 KKIIQLHDGDVIAQNNKPQGLKMII 318
Cdd:cd16975 81 KNLVEKHGGSLIIENSQKGGAEVTV 105
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
218-322 |
2.81e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 65.14 E-value: 2.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 218 LIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRsqTGNGLGLSLVKKII 297
Cdd:cd16943 3 QLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVG--EGTGLGLSLSYRII 80
|
90 100
....*....|....*....|....*
gi 2164748496 298 QLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:cd16943 81 QKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
116-321 |
1.85e-12 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 67.34 E-value: 1.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 116 NIAHDLKTPLTRLKNKLENLK-QTNPNKDSSDAL----AECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIID---- 186
Cdd:PRK11006 210 NVSHELRTPLTVLQGYLEMMQdQPLEGALREKALhtmrEQTQRMEGLVKQLLTLSKIEAAPTIDLNEKVDVPMMLRvler 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 187 DAIELYEpifEQKNIRLKINilpRNLNI--DKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINN 264
Cdd:PRK11006 290 EAQTLSQ---GKHTITFEVD---NSLKVfgNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAEFSVEDNGPGIAP 363
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2164748496 265 ENTNKIFERFFREEKSRS-QT-GNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLP 321
Cdd:PRK11006 364 EHIPRLTERFYRVDKARSrQTgGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
221-321 |
2.27e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 62.59 E-value: 2.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 221 QSIINILDNCYKYSKDNT-EISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQTG--NGLGLSLVKKII 297
Cdd:cd16953 3 QVLRNLIGNAISFSPPDTgRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFGqhSGLGLSISRQII 82
|
90 100
....*....|....*....|....*...
gi 2164748496 298 QLHDGDVIAQNNKP----QGLKMIISLP 321
Cdd:cd16953 83 EAHGGISVAENHNQpgqvIGARFTVQLP 110
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
225-321 |
2.85e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 62.34 E-value: 2.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 225 NILDNCYKYS--KDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDG 302
Cdd:cd16921 7 NLLGNAIKFRrpRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSREEYEGTGVGLAIVRKIIERHGG 86
|
90
....*....|....*....
gi 2164748496 303 DVIAQNNKPQGLKMIISLP 321
Cdd:cd16921 87 RIWLESEPGEGTTFYFTLP 105
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
197-322 |
1.11e-11 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 64.87 E-value: 1.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 197 EQKNIRLKINI--LPRNLNIDKNLIFqSII-NILDN----CYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNK 269
Cdd:COG3290 258 RERGIDLTIDIdsDLPDLPLSDTDLV-TILgNLLDNaieaVEKLPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEK 336
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2164748496 270 IFERFFReekSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:COG3290 337 IFERGFS---TKLGEGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLPK 386
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
117-322 |
2.54e-11 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 64.54 E-value: 2.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENL--KQTNPN-KDSSDALAECNQ-LLDIFNSLLRLNRLEHGREN--LIKKRLDIKNIIDDAIE 190
Cdd:PRK11466 451 MSHEIRTPLYGILGTAQLLadNPALNAqRDDLRAITDSGEsLLTILNDILDYSAIEAGGKNvsVSDEPFEPRPLLESTLQ 530
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 191 LYEPIFEQKNIRLKINI---LPRNLNIDKNLIFQSIINILDNCYKYSkDNTEISINTKIQNSKYIIEIADQGIGINNENT 267
Cdd:PRK11466 531 LMSGRVKGRPIRLATDIaddLPTALMGDPRRIRQVITNLLSNALRFT-DEGSIVLRSRTDGEQWLVEVEDSGCGIDPAKL 609
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2164748496 268 NKIFERFFREEKSRSqtGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:PRK11466 610 AEIFQPFVQVSGKRG--GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPL 662
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
104-322 |
3.07e-11 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 64.04 E-value: 3.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 104 EELLVDIKSVSNNIAHDLKTPLTRLKNKLENLKQTNPNKDSSDALA-----ECNQLLDIFNSLLRLNRLEHgrenLIKKR 178
Cdd:PRK10364 231 KEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAqvmakEADRLNRVVSELLELVKPTH----LALQA 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 179 LDIKNIIDDAIELYEPIFEQKNIRLKINI---LPRnLNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEI 255
Cdd:PRK10364 307 VDLNDLINHSLQLVSQDANSREIQLRFTAndtLPE-IQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISV 385
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2164748496 256 ADQGIGINNENTNKIFERFFreeKSRSQtGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:PRK10364 386 TDSGKGIAADQLEAIFTPYF---TTKAE-GTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPV 448
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
222-301 |
3.99e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 59.14 E-value: 3.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 222 SIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQ--TGNGLGLSLVKKIIQL 299
Cdd:cd16952 4 AFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRntGGTGLGLAIVKHVMSR 83
|
..
gi 2164748496 300 HD 301
Cdd:cd16952 84 HD 85
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
223-322 |
8.65e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 58.21 E-value: 8.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 223 IINILDNCYKYSkdNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRSQT--GNGLGLSLVKKIIQLH 300
Cdd:cd16939 5 LDNLLRNALRYA--HRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRAtgGFGLGLAIVHRVALWH 82
|
90 100
....*....|....*....|..
gi 2164748496 301 DGDVIAQNNKPQGLKMIISLPL 322
Cdd:cd16939 83 GGHVECDDSELGGACFRLTWPR 104
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
88-318 |
9.34e-11 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 62.34 E-value: 9.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 88 DLSNLANILNILLANIEELLVDIKSVSNNIAHDLKTPLTRLKNKLENLKqtnPNKDSSDALAE---------CNQLLDIF 158
Cdd:PRK10815 244 ELTSLVRNLNRLLKNERERYTKYRTTLTDLTHSLKTPLAVLQSTLRSLR---SGKQMSVEQAEpimleqisrISQQIGYY 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 159 nsLLRLNRleHGRENLIKKRL-DIKNIIDDAIELYEPIFEQKNIRLKINILPRNLNI-DKNLIFQSIINILDNCYKYSKD 236
Cdd:PRK10815 321 --LHRASM--RSEHNLLSRELhSVAPLLDNLTSALNKVYQRKGVNITLDISPEITFVgEKNDFMEVMGNVLDNACKYCLE 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 237 NTEISInTKIQNSKYIIeIADQGIGINNENTNKIFERFFREEKSRSqtGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKM 316
Cdd:PRK10815 397 FVEISA-RQTDEHLHIV-VEDDGPGIPESKRELIFDRGQRADTLRP--GQGLGLSVAREITEQYEGKISAGDSPLGGARM 472
|
..
gi 2164748496 317 II 318
Cdd:PRK10815 473 EV 474
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
225-321 |
1.83e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 57.30 E-value: 1.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 225 NILDNCYKYSKD----NTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFreeKSRSQTGNGLGLSLVKKIIQLH 300
Cdd:cd16915 7 NLIDNALDALAAtgapNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGV---STKGQGERGIGLALVRQSVERL 83
|
90 100
....*....|....*....|.
gi 2164748496 301 DGDVIAQNNKPQGLKMIISLP 321
Cdd:cd16915 84 GGSITVESEPGGGTTFSIRIP 104
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
195-320 |
2.80e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 57.64 E-value: 2.80e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 195 IFEQKNIRLKINILPR-NLNIDKNLIFQSIINILDNCYKYSKDNTEISIntkIQNS-KYIIEIADQGIGINNENTNKIFE 272
Cdd:cd16954 13 VYQRKGVSISLDISPElRFPGERNDLMELLGNLLDNACKWCLEFVEVTA---RQTDgGLHLIVDDDGPGVPESQRSKIFQ 89
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2164748496 273 RFFREEKSRSqtGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISL 320
Cdd:cd16954 90 RGQRLDEQRP--GQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
117-322 |
5.15e-10 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 60.34 E-value: 5.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPL------TR--LKNKL--ENLKQTNPNKDSSDALAecnqllDIFNSLLRLNRLEHGRENLIKKRLDIKNIID 186
Cdd:PRK11091 290 ISHELRTPLngivglSRilLDTELtaEQRKYLKTIHVSAITLG------NIFNDIIDMDKMERRKLQLDNQPIDFTDFLA 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 187 DAIELYEPIFEQKNIRLKINI---LPRNLNIDKNLIFQSIINILDNCYKYSKDNtEISINTKIQNSKYI-IEIADQGIGI 262
Cdd:PRK11091 364 DLENLSGLQAEQKGLRFDLEPllpLPHKVITDGTRLRQILWNLISNAVKFTQQG-GVTVRVRYEEGDMLtFEVEDSGIGI 442
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2164748496 263 NNENTNKIFERFFREEKS---RSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:PRK11091 443 PEDELDKIFAMYYQVKDShggKPATGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIHA 505
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
205-311 |
8.49e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 55.98 E-value: 8.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 205 INILPRNL--NIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKSRS 282
Cdd:cd16947 5 INIPDRPIyaNANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSRN 84
|
90 100 110
....*....|....*....|....*....|.
gi 2164748496 283 QT--GNGLGLSLVKKIIQLHDGDvIAQNNKP 311
Cdd:cd16947 85 SAkqGNGLGLTITKRLAESMGGS-IYVNSKP 114
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
219-313 |
3.38e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 50.53 E-value: 3.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 219 IFQSIINILDNCYK--YSKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFREEKsrSQTGNGLGLSLVKKI 296
Cdd:cd16976 1 IQQVLMNLLQNALDamGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKP--VGKGTGLGLSISYGI 78
|
90
....*....|....*..
gi 2164748496 297 IQLHDGDVIAQNNKPQG 313
Cdd:cd16976 79 VEEHGGRLSVANEEGAG 95
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
178-322 |
1.92e-07 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 52.21 E-value: 1.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 178 RLDIKNIIDDAIELYEPIFEQKNIRLKINILPRNLNIDKNLIFQSIIN-ILDNCYKY---SKDNTEISINTKIQNSKYII 253
Cdd:COG3920 358 GVDLRDYLRELLEPLRDSYGGRGIRIELDGPDVELPADAAVPLGLILNeLVTNALKHaflSGEGGRIRVSWRREDGRLRL 437
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2164748496 254 EIADQGIGINnentnkiferffreEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNnkPQGLKMIISLPL 322
Cdd:COG3920 438 TVSDNGVGLP--------------EDVDPPARKGLGLRLIRALVRQLGGTLELDR--PEGTRVRITFPL 490
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
116-323 |
2.38e-07 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 52.16 E-value: 2.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 116 NIAHDLKTPL------TR--LKNKLeNLKQTnpnkdssDALA----ECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKN 183
Cdd:PRK11107 299 NMSHELRTPLngvigfTRqtLKTPL-TPTQR-------DYLQtierSANNLLAIINDILDFSKLEAGKLVLENIPFSLRE 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 184 IIDDAIELYEPIFEQKNIRLKINI---LPRNLNIDKNLIFQSIINILDNCYKYS-KDNTEISINTKIQNSKYI---IEIA 256
Cdd:PRK11107 371 TLDEVVTLLAHSAHEKGLELTLNIdpdVPDNVIGDPLRLQQIITNLVGNAIKFTeSGNIDILVELRALSNTKVqleVQIR 450
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 257 DQGIGINNENTNKIFERFFREEKS--RSQTGNGLGLSLVKKIIQLHDGDvIAQNNKP-QGLKMIISLPLH 323
Cdd:PRK11107 451 DTGIGISERQQSQLFQAFRQADASisRRHGGTGLGLVITQKLVNEMGGD-ISFHSQPnRGSTFWFHLPLD 519
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
63-321 |
6.75e-07 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 50.60 E-value: 6.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 63 IASSAASIVNTRDF-SQRIKSN-----TNWDDLSNLANILNILLAniEELLVDIKSV-SNNIAHDLKTPLTRLKNKLENL 135
Cdd:PRK15053 265 LGKPIAEVVRPADFfTEQIDEKrqdvvANFNGLSVIANREAIRSG--DDLLGAIISFrSKDEISTLNAQLTQIKQYVESL 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 136 KQTNpnkdssdalAECNQLLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDD----------AIELYEPIFEQKNIRLKI 205
Cdd:PRK15053 343 RTLR---------HEHLNWMSTLNGLLQMKEYDRVLEMVQGESQAQQQLIDSlreafadrqvAGLLFGKVQRARELGLKM 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 206 NILPRNL------NIDKNLIFQSIINILDNCYKYSKDNTE----ISINTKIQNSKYIIEIADQGIGINNENTNKIFERFF 275
Cdd:PRK15053 414 VIVPGSQlsqlppGLDSTEFAAIVGNLLDNAFEASLRSDEgnkiVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGV 493
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2164748496 276 rEEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLP 321
Cdd:PRK15053 494 -STRADEPGEHGIGLYLIASYVTRCGGVITLEDNDPCGTLFSIFIP 538
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
215-313 |
7.46e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 47.15 E-value: 7.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 215 DKNLIFQSIINILDNCYKYSK----DNTEISINTKI-QNSKYIIEIADQGIGINNENTNKIFERFFreekSRSQTGNGLG 289
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEgrpsDVGEVRIRVEAdQDGRIVLIVCDNGKGFPREMRHRATEPYV----TTRPKGTGLG 76
|
90 100
....*....|....*....|....
gi 2164748496 290 LSLVKKIIQLHDGdVIAQNNKPQG 313
Cdd:cd16944 77 LAIVKKIMEEHGG-RISLSNREAG 99
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
116-170 |
8.09e-07 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 45.67 E-value: 8.09e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2164748496 116 NIAHDLKTPLTRLKNKLENLKQTNPNKDSSDAL----AECNQLLDIFNSLLRLNRLEHG 170
Cdd:pfam00512 8 NLSHELRTPLTAIRGYLELLRDEKLDEEQREYLetilRSAERLLRLINDLLDLSRIEAG 66
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
253-322 |
1.60e-06 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 49.68 E-value: 1.60e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 253 IEIADQGIGINNENTNKIFERFFreeKSRSQtGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPL 322
Cdd:PRK13837 610 LRVSDTGAGIDEAVLPHIFEPFF---TTRAG-GTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDVYLPP 675
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
116-170 |
1.63e-06 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 44.86 E-value: 1.63e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2164748496 116 NIAHDLKTPLTRLKNKLENLKQTNPNKDSSDAL----AECNQLLDIFNSLLRLNRLEHG 170
Cdd:smart00388 8 NLSHELRTPLTAIRGYLELLLDTELSEEQREYLetilREAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
219-321 |
2.78e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 45.47 E-value: 2.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 219 IFQSIINILDNCYKYSKDNT-EISINTKIQNSKYI----------IEIADQGIGINNENTNKIFERFF--REEksrsqtG 285
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSGgEIILRTRTQRQVTLghprhrlalrVSVIDNGPGIPPDLQDTIFYPMVsgREN------G 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 2164748496 286 NGLGLSLVKKIIQLHDGdVIAQNNKPQGLKMIISLP 321
Cdd:cd16918 75 TGLGLAIAQNIVSQHGG-VIECDSQPGHTVFSVSLP 109
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
35-322 |
3.07e-06 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 48.48 E-value: 3.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 35 LSIGIFCTVSVVIISYLISVFVVRKINHIASSAASIVNTRDFSQRIKSNtnwDDLSNLANILNILLANIEELLVDIKSVS 114
Cdd:COG2972 160 LLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLVRLEVSGN---DEIGILARSFNEMVERIKELIEEVYELE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 115 NNIAHdlktplTRLK------------NKLENLKQTNPNKDSSDAlaecNQLLDIFNSLLRLNRLEHGRENLIKKRLD-I 181
Cdd:COG2972 237 LEKKE------AELKalqaqinphflfNTLNSIRWLAELEDPEEA----EEMLEALSKLLRYSLSKGDELVTLEEELElI 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 182 KNIIddAIELYEpiFEQKnIRLKINI--LPRNLNIDKnLIFQSIInilDNCYKY----SKDNTEISINTKIQNSKYIIEI 255
Cdd:COG2972 307 KSYL--EIQKLR--FGDR-LEVEIEIdeELLDLLIPK-LILQPLV---ENAIEHgiepKEGGGTIRISIRKEGDRLVITV 377
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 256 ADQGIGINNENTNKIFERFfreekSRSQTGNGLGLSLVKKIIQLHDGD---VIAQNNKPQGLKMIISLPL 322
Cdd:COG2972 378 EDNGVGMPEEKLEKLLEEL-----SSKGEGRGIGLRNVRERLKLYYGEeygLEIESEPGEGTTVTIRIPL 442
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
117-323 |
3.33e-06 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 48.82 E-value: 3.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 117 IAHDLKTPLTRLKNKLENLKQTNPNKDSSDALAECNQ----LLDIFNSLLRLNRLEHGRENLIKKRLDIKNIIDDAIELY 192
Cdd:PRK10841 454 VSHELRTPLYGIIGNLDLLQTKELPKGVDRLVTAMNNssslLLKIISDILDFSKIESEQLKIEPREFSPREVINHITANY 533
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 193 EPIFEQKNIRLKINI---LPRNLNIDKNLIFQSIINILDNCYKYSkDNTEISINTKIQNSKYIIEIADQGIGINNENTNK 269
Cdd:PRK10841 534 LPLVVKKRLGLYCFIepdVPVALNGDPMRLQQVISNLLSNAIKFT-DTGCIVLHVRVDGDYLSFRVRDTGVGIPAKEVVR 612
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2164748496 270 IFERFFR--EEKSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLPLH 323
Cdd:PRK10841 613 LFDPFFQvgTGVQRNFQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIPLY 668
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
219-321 |
1.03e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 43.54 E-value: 1.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 219 IFQSIINILDNCYKYSKDNT----EISINTKIQNSKY-IIEIADQGIGINNENTNKIFERFFREEKSrsqtGNGLGLSLV 293
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEGGcerrELTIRTSPADDRAvTISVKDTGPGIAEEVAGQLFDPFYTTKSE----GLGMGLSIC 76
|
90 100
....*....|....*....|....*...
gi 2164748496 294 KKIIQLHDGDVIAQNNKPQGLKMIISLP 321
Cdd:cd16920 77 RSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
116-166 |
4.51e-05 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 40.66 E-value: 4.51e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2164748496 116 NIAHDLKTPLTRLKNKLENLKQTNPNKDSSD-----ALAECNQLLDIFNSLLRLNR 166
Cdd:cd00082 10 NVSHELRTPLTAIRGALELLEEELLDDEEQReylerIREEAERLLRLINDLLDLSR 65
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
1-118 |
5.38e-05 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 44.63 E-value: 5.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 1 MAMLFTVLLGLSIVSWIYIIFSAVGDRVIEHIIPLSIGIFCTVSVVIISYLISVFVVRKINHIASSAASIVNtRDFSQRI 80
Cdd:COG0840 151 ALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAE-GDLTVRI 229
|
90 100 110
....*....|....*....|....*....|....*...
gi 2164748496 81 KSNTNwDDLSNLANILNILLANIEELLVDIKSVSNNIA 118
Cdd:COG0840 230 DVDSK-DEIGQLADAFNRMIENLRELVGQVRESAEQVA 266
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
234-321 |
2.26e-04 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 42.59 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 234 SKDNTEISINTKIQNSKYIIEIADQGIGINNENTNKIFERFFreekSRSQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQG 313
Cdd:PRK11086 451 GEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGY----STKGSNRGVGLYLVKQSVENLGGSIAVESEPGVG 526
|
....*...
gi 2164748496 314 LKMIISLP 321
Cdd:PRK11086 527 TQFFVQIP 534
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
179-308 |
3.43e-04 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 42.37 E-value: 3.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 179 LDIKNIIDDAIELYEPIFEQKNIRLKINILPrNLNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQ 258
Cdd:COG4192 505 VDLRQVIEQAWELVESRAKPQQITLHIPDDL-MVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRVAISDN 583
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2164748496 259 GIGINnentnkIFERFFREEKSRSQTGNGLGLSLVKKIIQLHDGDV-IAQN 308
Cdd:COG4192 584 GNGWP------LVDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLyLAST 628
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
253-321 |
8.08e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 38.51 E-value: 8.08e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2164748496 253 IEIADQGIGINNENTNKIFERFF--REEKSrsqtGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISLP 321
Cdd:cd16919 50 LEVSDTGSGMPAEVLRRAFEPFFttKEVGK----GTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_ETR2_ERS2-EIN4-like |
cd16938 |
Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related ... |
208-320 |
6.34e-03 |
|
Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related domains; This family includes the histidine kinase-like ATPase domains (HATPase) of three out of the five receptors that recognize the plant hormone ethylene in Arabidopsis thaliana. These three proteins have been classified as belonging to subfamily 2: ETR2, ERS2, and EIN4. They lack most of the motifs characteristic of histidine kinases, and EIN4 is the only one in this group containing the conserved histidine that is phosphorylated in two-component and phosphorelay systems. This family also includes the HATPase domains of Escherichia coli RcsD phosphotransferase which is a component of the Rcs-signaling system, a complex multistep phosphorelay involving five proteins, and is involved in many transcriptional networks such as cell division, biofilm formation, and virulence, among others. Also included is Schizosaccharomyces pombe Mak3 (Phk1) which participates in a multi-step two-component related system which regulates H2O2-induced activation of the Sty1 stress-activated protein kinase pathway. Most proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a GAF sensor domain; most are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340415 [Multi-domain] Cd Length: 133 Bit Score: 36.28 E-value: 6.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164748496 208 LPRNLNIDKNLIFQSIINILDNCYKYSKDNTEISINTKIQNSKYIIEIADQG----------------IGINNENTNKIF 271
Cdd:cd16938 1 LPDVVVGDERRVFQVLLHMLGNLLKMRNGGGNITFRVFLEGGSEDRSDRDWGpwrpsmsdesveirfeVEINDSGSPSIE 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2164748496 272 ERFFREEKSR----SQTGNGLGLSLVKKIIQLHDGDVIAQNNKPQGLKMIISL 320
Cdd:cd16938 81 SASMRNSLNRrynlSELGEHLSFSICKQLVQLMGGNIWIVPGSGLGTTMSLLL 133
|
|
| |
