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Conserved domains on  [gi|2168732169|ref|WP_232515690|]
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MULTISPECIES: helix-turn-helix transcriptional regulator [Aeribacillus]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 10007659)

helix-turn-helix (HTH) domain-containing protein with an XRE (Xenobiotic Response Element) family HTH domain, binds DNA and may function as a transcriptional regulator

CATH:  1.10.10.10
Gene Ontology:  GO:0003677
PubMed:  15808743|2644244|8831795
SCOP:  4000362

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YozG COG3655
DNA-binding transcriptional regulator, XRE family [Transcription];
8-75 7.63e-14

DNA-binding transcriptional regulator, XRE family [Transcription];


:

Pssm-ID: 442872 [Multi-domain]  Cd Length: 69  Bit Score: 59.77  E-value: 7.63e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2168732169  8 IHIKLDNLLKQKRMTKRELARQADIRHTLVWEMCHNKTKRLPLDKLAKICSVLQVDIHDVIELVERKE 75
Cdd:COG3655    2 IYVKLDELLAERGMTKKELAEATGISRATLSRLKNGKAKAVRLDTLEKICKALDCQPGDLLEYVPDEE 69
 
Name Accession Description Interval E-value
YozG COG3655
DNA-binding transcriptional regulator, XRE family [Transcription];
8-75 7.63e-14

DNA-binding transcriptional regulator, XRE family [Transcription];


Pssm-ID: 442872 [Multi-domain]  Cd Length: 69  Bit Score: 59.77  E-value: 7.63e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2168732169  8 IHIKLDNLLKQKRMTKRELARQADIRHTLVWEMCHNKTKRLPLDKLAKICSVLQVDIHDVIELVERKE 75
Cdd:COG3655    2 IYVKLDELLAERGMTKKELAEATGISRATLSRLKNGKAKAVRLDTLEKICKALDCQPGDLLEYVPDEE 69
HTH_26 pfam13443
Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to ...
 11-71 1.19e-11

Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433211 [Multi-domain]  Cd Length: 63  Bit Score: 54.08  E-value: 1.19e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2168732169 11 KLDNLLKQKRMTKRELARQADIRHTLVWEMCHNKTKRLPLDKLAKICSVLQVDIHDVIELV 71
Cdd:pfam13443  1 KLRKLMADRGISKSDLARATGISRATLSRLRKGKPKRVSLDTLDKICDALGCQPGDLLEYV 61
 
Name Accession Description Interval E-value
YozG COG3655
DNA-binding transcriptional regulator, XRE family [Transcription];
8-75 7.63e-14

DNA-binding transcriptional regulator, XRE family [Transcription];


Pssm-ID: 442872 [Multi-domain]  Cd Length: 69  Bit Score: 59.77  E-value: 7.63e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2168732169  8 IHIKLDNLLKQKRMTKRELARQADIRHTLVWEMCHNKTKRLPLDKLAKICSVLQVDIHDVIELVERKE 75
Cdd:COG3655    2 IYVKLDELLAERGMTKKELAEATGISRATLSRLKNGKAKAVRLDTLEKICKALDCQPGDLLEYVPDEE 69
HTH_26 pfam13443
Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to ...
 11-71 1.19e-11

Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433211 [Multi-domain]  Cd Length: 63  Bit Score: 54.08  E-value: 1.19e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2168732169 11 KLDNLLKQKRMTKRELARQADIRHTLVWEMCHNKTKRLPLDKLAKICSVLQVDIHDVIELV 71
Cdd:pfam13443  1 KLRKLMADRGISKSDLARATGISRATLSRLRKGKPKRVSLDTLDKICDALGCQPGDLLEYV 61
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-72 1.49e-03

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 33.82  E-value: 1.49e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2168732169  1 MEKKEYVIHIKLDNLLKQKRMTKRELARQADIRHTLV--WEmchNKTKRLPLDKLAKICSVLQVDIHDVIELVE 72
Cdd:COG1396    1 MSTLKKALGERLRELRKARGLTQEELAERLGVSRSTIsrIE---RGRRNPSLETLLKLAKALGVSLDELLGGAD 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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