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Conserved domains on  [gi|2169656470|ref|WP_232735529|]
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MAE_28990/MAE_18760 family HEPN-like nuclease [Pseudoalteromonas sp. 3J6]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
HEPN_RiboL-PSP pfam18735
RiboL-PSP-HEPN; RiboL-PSP-HEPN. Fused to endoRNase L-PSP; in operon with ParB.
16-210 7.22e-26

RiboL-PSP-HEPN; RiboL-PSP-HEPN. Fused to endoRNase L-PSP; in operon with ParB.


:

Pssm-ID: 465851  Cd Length: 191  Bit Score: 99.26  E-value: 7.22e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2169656470  16 ERAWRRKELTNLKSLIHQS--RDAHNKTLVRAGVLLLYSHWEGYVKKVCEAFFHYLNFKAHKYSELQPNFLAVGIANQFN 93
Cdd:pfam18735   2 DLLWRLKELSKLLKSLNDIssDPELQEVLRRALIVLLYAHLEGFVKDLLKEYLEEINSKKLLYSDLKKNFLILRLLHELE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2169656470  94 GNFPQKRFGSYLKSVNFvlNDASNLKFRIDVGSRVDTKSNLTTEVLVELLNMLGINTEHFTNNQQYIDSkLLKYRNAIAH 173
Cdd:pfam18735  82 KFDWKKKNKNKELLKDL--LKLFGENFSEKFNKIIDTESNLKKKVLKEILKRLGIDLSKFELKESILNS-LVKRRNDIAH 158
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2169656470 174 GerteNNPDLSIDEDEFNEIYTRVNSLVDHFESIVCN 210
Cdd:pfam18735 159 G----NDTATDITFDELKEYIDFIKKLVEAIDELLEN 191
 
Name Accession Description Interval E-value
HEPN_RiboL-PSP pfam18735
RiboL-PSP-HEPN; RiboL-PSP-HEPN. Fused to endoRNase L-PSP; in operon with ParB.
16-210 7.22e-26

RiboL-PSP-HEPN; RiboL-PSP-HEPN. Fused to endoRNase L-PSP; in operon with ParB.


Pssm-ID: 465851  Cd Length: 191  Bit Score: 99.26  E-value: 7.22e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2169656470  16 ERAWRRKELTNLKSLIHQS--RDAHNKTLVRAGVLLLYSHWEGYVKKVCEAFFHYLNFKAHKYSELQPNFLAVGIANQFN 93
Cdd:pfam18735   2 DLLWRLKELSKLLKSLNDIssDPELQEVLRRALIVLLYAHLEGFVKDLLKEYLEEINSKKLLYSDLKKNFLILRLLHELE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2169656470  94 GNFPQKRFGSYLKSVNFvlNDASNLKFRIDVGSRVDTKSNLTTEVLVELLNMLGINTEHFTNNQQYIDSkLLKYRNAIAH 173
Cdd:pfam18735  82 KFDWKKKNKNKELLKDL--LKLFGENFSEKFNKIIDTESNLKKKVLKEILKRLGIDLSKFELKESILNS-LVKRRNDIAH 158
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2169656470 174 GerteNNPDLSIDEDEFNEIYTRVNSLVDHFESIVCN 210
Cdd:pfam18735 159 G----NDTATDITFDELKEYIDFIKKLVEAIDELLEN 191
 
Name Accession Description Interval E-value
HEPN_RiboL-PSP pfam18735
RiboL-PSP-HEPN; RiboL-PSP-HEPN. Fused to endoRNase L-PSP; in operon with ParB.
16-210 7.22e-26

RiboL-PSP-HEPN; RiboL-PSP-HEPN. Fused to endoRNase L-PSP; in operon with ParB.


Pssm-ID: 465851  Cd Length: 191  Bit Score: 99.26  E-value: 7.22e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2169656470  16 ERAWRRKELTNLKSLIHQS--RDAHNKTLVRAGVLLLYSHWEGYVKKVCEAFFHYLNFKAHKYSELQPNFLAVGIANQFN 93
Cdd:pfam18735   2 DLLWRLKELSKLLKSLNDIssDPELQEVLRRALIVLLYAHLEGFVKDLLKEYLEEINSKKLLYSDLKKNFLILRLLHELE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2169656470  94 GNFPQKRFGSYLKSVNFvlNDASNLKFRIDVGSRVDTKSNLTTEVLVELLNMLGINTEHFTNNQQYIDSkLLKYRNAIAH 173
Cdd:pfam18735  82 KFDWKKKNKNKELLKDL--LKLFGENFSEKFNKIIDTESNLKKKVLKEILKRLGIDLSKFELKESILNS-LVKRRNDIAH 158
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2169656470 174 GerteNNPDLSIDEDEFNEIYTRVNSLVDHFESIVCN 210
Cdd:pfam18735 159 G----NDTATDITFDELKEYIDFIKKLVEAIDELLEN 191
HEPN_MAE_28990 pfam18737
MAE_28990/MAE_18760-like HEPN; HEPN-like nuclease. MAE_28990 In operon with a ParB nuclease ...
9-217 9.76e-24

MAE_28990/MAE_18760-like HEPN; HEPN-like nuclease. MAE_28990 In operon with a ParB nuclease and DNA methylase genes. MAE_18760-like HEPN found fused to HEPN/RES-NTD1, HEPN/Toprim-NTD1, Schlafen and a novel beta rich domain. In operon with ParA/Soj ATPase of SIMIBI-type GTPase fold.


Pssm-ID: 436702  Cd Length: 210  Bit Score: 93.97  E-value: 9.76e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2169656470   9 FLDAIQLERAWRRKELTNLKSL---IHQSRDAHNKTLVRAGVLLLYSHWEGYVKKVCEAFFHYLNFKAHKYSELQPNFLA 85
Cdd:pfam18737   1 LLSELSEDLAWRKKEISELKILlesLSQSDRQLKKILRASLILLLYAHWEGFVKNALEAYLDYLNSLGLTYSDLSPEFRA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2169656470  86 VGIANQFNgNFPQKRFGSYLKSVNFV---LNDASNLKFRIDVGsrvdTKSNLTTEVLVE---LLNMLGINTEHFTNNQQY 159
Cdd:pfam18737  81 LAKKEALK-NLKQKKPERLLTALVNFkslFLDLIQAFFYKDLS----TGSNLDSEVIKNisdILQNLGIDLSTDYKKTIK 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2169656470 160 ID--SKLLKYRNAIAHGERTEnnpdlSIDEDEFNEIYTRVNSLVDHFESIVCNHVELETY 217
Cdd:pfam18737 156 IDleNTLVNRRNDIAHGEKSI-----DLDVEELLKLEDKVIALLRELADNIEDYLSKRKY 210
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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