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Conserved domains on  [gi|2178196832|ref|WP_234397268|]
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tol-pal system YbgF family protein [Polynucleobacter asymbioticus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11448200)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes; similar to Schizosaccharomyces pombe mitochondrial pentatricopeptide repeat-containing protein 4

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 36-113 7.10e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.21  E-value: 7.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  36 YQAIESGQLAKADSMMQEVLKNHPNS---GKAHYIASELYLKEGKLDAARNAFVQAENLAPGLPFVqPESVQKL-QAQLR 111
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKA-PDALLKLgLSYLE 79


                  ..
gi 2178196832 112 AG 113
Cdd:COG1729    80 LG 81
 
Name Accession Description Interval E-value
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 36-113 7.10e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.21  E-value: 7.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  36 YQAIESGQLAKADSMMQEVLKNHPNS---GKAHYIASELYLKEGKLDAARNAFVQAENLAPGLPFVqPESVQKL-QAQLR 111
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKA-PDALLKLgLSYLE 79


                  ..
gi 2178196832 112 AG 113
Cdd:COG1729    80 LG 81
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 35-106 3.62e-04

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 39.19  E-value: 3.62e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2178196832  35 VYQAIESGQLAKADSMMQEVLKNHPNS---GKAHYIASELYLKEGKLDAARNAFVQAENLAPGLPFVqPESVQKL 106
Cdd:TIGR02795   7 ALLVLKAGDYADAIQAFQAFLKKYPKStyaPNAHYWLGEAYYAQGDYADAAKAFLAVVKKYPKSPKA-PDALLKL 80
TPR_19 pfam14559
Tetratricopeptide repeat;
41-110 7.32e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.18  E-value: 7.32e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  41 SGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPglpfvQPESVQKLQAQL 110
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADP-----DDPRYAALLAKL 65
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 38-93 4.94e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 37.61  E-value: 4.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2178196832  38 AIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAP 93
Cdd:cd24142    10 LLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
 
Name Accession Description Interval E-value
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 36-113 7.10e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.21  E-value: 7.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  36 YQAIESGQLAKADSMMQEVLKNHPNS---GKAHYIASELYLKEGKLDAARNAFVQAENLAPGLPFVqPESVQKL-QAQLR 111
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKA-PDALLKLgLSYLE 79


                  ..
gi 2178196832 112 AG 113
Cdd:COG1729    80 LG 81
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 14-98 1.43e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 1.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  14 LFASAMLLTSNVAFAEPTLPEVYQAIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAP 93
Cdd:COG5010    40 DELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSP 119


                  ....*
gi 2178196832  94 GLPFV 98
Cdd:COG5010   120 DNPNA 124
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 37-115 2.88e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.33  E-value: 2.88e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2178196832  37 QAIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPGLPFVQPESVQKLQAQLRAGAA 115
Cdd:COG2956   153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEA 231
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 12-98 3.08e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.87  E-value: 3.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  12 IGLFASAMLLTSNVAFAEPTLPEVYQA-----IESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFV 86
Cdd:COG4783    17 AGDYDEAEALLEKALELDPDNPEAFALlgeilLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLE 96

                          90
                  ....*....|..
gi 2178196832  87 QAENLAPGLPFV 98
Cdd:COG4783    97 KALKLDPEHPEA 108
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 37-96 1.94e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 1.94e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  37 QAIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPGLP 96
Cdd:COG4783    13 ALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP 72
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 37-113 2.24e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 2.24e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2178196832  37 QAIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPglpfvqpesvQKLQAQLRAG 113
Cdd:COG2956    17 NYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDP----------DRAEALLELA 83
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 13-93 3.29e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.25  E-value: 3.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  13 GLFASAMLLTSNVAFAEPTLPEVYQAI-----ESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQ 87
Cdd:COG2956    90 GLLDRAEELLEKLLELDPDDAEALRLLaeiyeQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEK 169


                  ....*.
gi 2178196832  88 AENLAP 93
Cdd:COG2956   170 ALKLDP 175
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 35-106 3.62e-04

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 39.19  E-value: 3.62e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2178196832  35 VYQAIESGQLAKADSMMQEVLKNHPNS---GKAHYIASELYLKEGKLDAARNAFVQAENLAPGLPFVqPESVQKL 106
Cdd:TIGR02795   7 ALLVLKAGDYADAIQAFQAFLKKYPKStyaPNAHYWLGEAYYAQGDYADAAKAFLAVVKKYPKSPKA-PDALLKL 80
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 28-93 5.51e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.40  E-value: 5.51e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2178196832  28 AEPTLPEVYQAI-----ESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAP 93
Cdd:COG4783    67 LDPDEPEARLNLglallKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 39-93 5.62e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.22  E-value: 5.62e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2178196832  39 IESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAP 93
Cdd:COG4235    62 LAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 38-98 5.99e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.48  E-value: 5.99e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2178196832  38 AIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPGLPFV 98
Cdd:COG2956   188 YLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
TPR_19 pfam14559
Tetratricopeptide repeat;
41-110 7.32e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.18  E-value: 7.32e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  41 SGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPglpfvQPESVQKLQAQL 110
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADP-----DDPRYAALLAKL 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 41-93 9.19e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 9.19e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2178196832  41 SGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAP 93
Cdd:TIGR02917 749 SGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
38-96 1.46e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.07  E-value: 1.46e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2178196832  38 AIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARnAFVQAENLAPGLP 96
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNA 59
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 35-97 1.59e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.68  E-value: 1.59e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2178196832  35 VYQAIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPGLPF 97
Cdd:TIGR02917 438 ILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFP 500
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 51-96 1.87e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 1.87e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2178196832  51 MQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPGLP 96
Cdd:COG4235     6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNA 51
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 34-115 1.91e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 1.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  34 EVYQAieSGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPGLPFVQPESVQKLQAQLRAG 113
Cdd:COG2956    84 QDYLK--AGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYD 161


                  ..
gi 2178196832 114 AA 115
Cdd:COG2956   162 EA 163
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 12-93 2.02e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 2.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  12 IGLFASAMLLTSNVAFAEPTLPEVYQAieSGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENL 91
Cdd:COG2956    28 IDLLEEALELDPETVEAHLALGNLYRR--RGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL 105


                  ..
gi 2178196832  92 AP 93
Cdd:COG2956   106 DP 107
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 12-96 2.06e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.21  E-value: 2.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178196832  12 IGLFASAMLLTSNVAFAEPTLPEVYQAIesGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENL 91
Cdd:COG3914    98 LALYRRALALNPDNAEALFNLGNLLLAL--GRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALEL 175


                  ....*
gi 2178196832  92 APGLP 96
Cdd:COG3914   176 DPDNA 180
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 38-114 4.35e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 37.97  E-value: 4.35e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2178196832  38 AIESGQLAKADSMMQEVLKNHPNSGKA-HYIASELYLKEGKLDAARNAFVQAENLAPGLPfvqpeSVQKLQAQLRAGA 114
Cdd:COG3071    60 AQALGDYERRDEYLAQALELAPEAELAvLLTRAELLLDQGQAEQALATLEALRAGAPRHP-----QVLRLLLQAYRQL 132
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
29-96 4.69e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 37.68  E-value: 4.69e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2178196832  29 EPTLPEVYQAI-----ESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPGLP 96
Cdd:COG0457    72 DPDDAEALNNLglalqALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDA 144
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 38-93 4.94e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 37.61  E-value: 4.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2178196832  38 AIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAP 93
Cdd:cd24142    10 LLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 39-93 6.91e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 36.48  E-value: 6.91e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2178196832  39 IESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAP 93
Cdd:COG5010    99 SRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
39-95 7.48e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 35.15  E-value: 7.48e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2178196832  39 IESGQLAKADSMmQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPGL 95
Cdd:COG3063    37 LEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSA 92
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
29-96 9.45e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 36.52  E-value: 9.45e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2178196832  29 EPTLPEVYQAI-----ESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAPGLP 96
Cdd:COG0457     4 DPDDAEAYNNLglayrRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDA 76
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 30-93 9.93e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 36.81  E-value: 9.93e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178196832  30 PTLPEVYQAIESGQLAKADSMMQEVLKNHPNSGKAHYIASELYLKEGKLDAARNAFVQAENLAP 93
Cdd:COG3071   226 PRLVRLYGRLQGGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRP 289
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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