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Conserved domains on  [gi|2178847744|ref|WP_234594644|]
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bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase [Shewanella chilikensis]

Protein Classification

bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase( domain architecture ID 11437151)

bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase containing an N-terminal domain similar to ADP-forming acetate--CoA ligase that catalyzes the formation of acetate and ATP from acetyl-CoA by using ADP and phosphate, and a C-terminal domain that may catalyze the transfer of an acetyl group from acetyl-CoA to a substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-717 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


:

Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 909.50  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744   1 MSQRTLHTLFKPGSIAVIGASNSHKRAGNVVMKNLLSGGFAGPIMPVTPKYHAVMGVLAYPNIESLPIKPDLAIICTRAS 80
Cdd:COG1042     1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744  81 SVPAIVETLAQFGCKVAIIMASGMAdELNEQGENLLELTQGNARRYGMRILGPNSLGMMLPPQGLNASLAHAGALPGKIA 160
Cdd:COG1042    81 TVPDVVEECGEKGVKAAVVISAGFA-ETGEEGAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 161 FVSQSAAICTTVLDWANNKGIGFSSFISLGDATDIDFDELLDFLGRDSRTSAIMLYIDSVNEKRHFLSAARAAARHKPIL 240
Cdd:COG1042   160 LVSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVV 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 241 VIKSGRSAEGGNAAKLHTGGIAGNDAVYEAAFRRAGMLRVTDLVELFAALESLAHLNPLNGERLCILSNGGGPAVLAVDE 320
Cdd:COG1042   240 VLKSGRSEAGARAAASHTGALAGSDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 321 LVLKGGKLAQLSEATLDKLSQLLPSTWSGQNPVDIIGDAGAERYSQALSVLMDSDELDAILVLHSPSALGESVTIADALI 400
Cdd:COG1042   320 LEDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALI 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 401 ETVKQHSKrnrvSILTNWSGEDAAYRARKHFSKAGIPTYRTPEGAVRAFMHMVEYRRNQKLLQEVPQsiPDSIPTDSATA 480
Cdd:COG1042   400 EAAKGSGK----PVLASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA--SEDFDPDRERA 473

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 481 RSLLQQAIAKGKRVLETHDARNILNAYGLDTIDTWYAKDAAEAVAIADKAGYPVALKVQSPDILHKSDVHGVMLNLTSAN 560
Cdd:COG1042   474 RAIIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAE 553

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 561 EVNQAAAAIVERVHASNPAASVEGMIVQKMAltAGAQELRVAVISDPVFGPAIMLGEGGSEWEPTRDAAVALPPLNMALA 640
Cdd:COG1042   554 AVRAAFEEILARVRAARPDARIDGVLVQPMV--PGGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALA 631

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2178847744 641 RYMVIQALKTQKIRDRHLPQGLDMRALCLMLTQISQLIIDCPEIESLDLNPVLAAGEKITLLDVNLRLNPEVTDNAG 717
Cdd:COG1042   632 REMIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPPAPR 708
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 740-889 1.26e-12

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 66.95  E-value: 1.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 740 VMLRPILPEDEPKHLDFDNsltDED--RYKRYFGVRSRMTHEEMAVLTQIDYAREMAFIATIRDENGEeeTLGAVRAS-I 816
Cdd:COG1670     8 LRLRPLRPEDAEALAELLN---DPEvaRYLPGPPYSLEEARAWLERLLADWADGGALPFAIEDKEDGE--LIGVVGLYdI 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178847744 817 DPDNTEAEFAMAVRSSHQGIGIGKLLLEKLINYYRTT-GTQVLTGFTMFENRNMASLAKSLGFTVTFDMEEHLI 889
Cdd:COG1670    83 DRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALV 156
 
Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-717 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 909.50  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744   1 MSQRTLHTLFKPGSIAVIGASNSHKRAGNVVMKNLLSGGFAGPIMPVTPKYHAVMGVLAYPNIESLPIKPDLAIICTRAS 80
Cdd:COG1042     1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744  81 SVPAIVETLAQFGCKVAIIMASGMAdELNEQGENLLELTQGNARRYGMRILGPNSLGMMLPPQGLNASLAHAGALPGKIA 160
Cdd:COG1042    81 TVPDVVEECGEKGVKAAVVISAGFA-ETGEEGAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 161 FVSQSAAICTTVLDWANNKGIGFSSFISLGDATDIDFDELLDFLGRDSRTSAIMLYIDSVNEKRHFLSAARAAARHKPIL 240
Cdd:COG1042   160 LVSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVV 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 241 VIKSGRSAEGGNAAKLHTGGIAGNDAVYEAAFRRAGMLRVTDLVELFAALESLAHLNPLNGERLCILSNGGGPAVLAVDE 320
Cdd:COG1042   240 VLKSGRSEAGARAAASHTGALAGSDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 321 LVLKGGKLAQLSEATLDKLSQLLPSTWSGQNPVDIIGDAGAERYSQALSVLMDSDELDAILVLHSPSALGESVTIADALI 400
Cdd:COG1042   320 LEDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALI 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 401 ETVKQHSKrnrvSILTNWSGEDAAYRARKHFSKAGIPTYRTPEGAVRAFMHMVEYRRNQKLLQEVPQsiPDSIPTDSATA 480
Cdd:COG1042   400 EAAKGSGK----PVLASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA--SEDFDPDRERA 473

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 481 RSLLQQAIAKGKRVLETHDARNILNAYGLDTIDTWYAKDAAEAVAIADKAGYPVALKVQSPDILHKSDVHGVMLNLTSAN 560
Cdd:COG1042   474 RAIIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAE 553

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 561 EVNQAAAAIVERVHASNPAASVEGMIVQKMAltAGAQELRVAVISDPVFGPAIMLGEGGSEWEPTRDAAVALPPLNMALA 640
Cdd:COG1042   554 AVRAAFEEILARVRAARPDARIDGVLVQPMV--PGGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALA 631

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2178847744 641 RYMVIQALKTQKIRDRHLPQGLDMRALCLMLTQISQLIIDCPEIESLDLNPVLAAGEKITLLDVNLRLNPEVTDNAG 717
Cdd:COG1042   632 REMIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPPAPR 708
AcCoA-syn-alpha TIGR02717
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ...
 6-456 3.34e-162

acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.


Pssm-ID: 131764 [Multi-domain]  Cd Length: 447  Bit Score: 481.04  E-value: 3.34e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744   6 LHTLFKPGSIAVIGASNSHKRAGNVVMKNLLSGGFAGPIMPVTPKYHAVMGVLAYPNIESLPIKPDLAIICTRASSVPAI 85
Cdd:TIGR02717   1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744  86 VETLAQFGCKVAIIMASGMAdELNEQGENLLELTQGNARRYGMRILGPNSLGMMLPPQGLNASLAHAGALPGKIAFVSQS 165
Cdd:TIGR02717  81 VEECGEKGVKGAVVITAGFK-EVGEEGAELEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTMPKKGGIAFISQS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 166 AAICTTVLDWANNKGIGFSSFISLGDATDIDFDELLDFLGRDSRTSAIMLYIDSVNEKRHFLSAARAAARHKPILVIKSG 245
Cdd:TIGR02717 160 GALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKFLKTAREISKKKPIVVLKSG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 246 RSAEGGNAAKLHTGGIAGNDAVYEAAFRRAGMLRVTDLVELFAALESLAHLNPLNGERLCILSNGGGPAVLAVDELVLKG 325
Cdd:TIGR02717 240 TSEAGAKAASSHTGALAGSDEAYDAAFKQAGVIRADSIEELFDLARLLSNQPLPKGNRVAIITNAGGPGVIATDACEENG 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 326 GKLAQLSEATLDKLSQLLPSTWSGQNPVDIIGDAGAERYSQALSVLMDSDELDAILVLHSPSALGESVTIADALIETVKQ 405
Cdd:TIGR02717 320 LELAELSEATKNKLRNILPPEASIKNPVDVLGDATPERYAKALKTVAEDENVDGVVVVLTPTAMTDPEEVAKGIIEGAKK 399

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2178847744 406 HskrNRVSILTNWSGEDAAYRARKHFSKAGIPTYRTPEGAVRAFMHMVEYR 456
Cdd:TIGR02717 400 S---NEKPVVAGFMGGKSVDPAKRILEENGIPNYTFPERAVKALSALYRYA 447
ATP-grasp_5 pfam13549
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ...
 486-708 1.51e-91

ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.


Pssm-ID: 463918 [Multi-domain]  Cd Length: 221  Bit Score: 288.61  E-value: 1.51e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 486 QAIAKGKRVLETHDARNILNAYGLDTIDTWYAKDAAEAVAIADKAGYPVALKVQSPDILHKSDVHGVMLNLTSANEVNQA 565
Cdd:pfam13549   1 KALAEGRTVLTEPEAKALLAAYGIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 566 AAAIVERVHASNPAASVEGMIVQKMALtaGAQELRVAVISDPVFGPAIMLGEGGSEWEPTRDAAVALPPLNMALARYMvI 645
Cdd:pfam13549  81 YEEILERVRRYRPDARIEGVLVQPMAP--GGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREM-I 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178847744 646 QALKTQKIRDRHLPQ-GLDMRALCLMLTQISQLIIDCPEIESLDLNPVLAAGEKITLLDVNLRL 708
Cdd:pfam13549 158 RRTRAYKLLKGYRGEpPADLDALEDVLVRVSQLVIDFPEIRELDINPLLADEDGVVALDARIRL 221
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 9-103 3.50e-20

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 86.02  E-value: 3.50e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744    9 LFKPG-SIAVIGASNSHKRAGNVVMKNLLSGG--FAGPIMP--VTPKYHavmGVLAYPNIESLPIK--PDLAIICTRASS 81
Cdd:smart00881   1 LLNPNtSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYPgkVGPKVD---GVPVYDSVAEAPEEtgVDVAVIFVPAEA 77

                           90       100
                   ....*....|....*....|..
gi 2178847744   82 VPAIVETLAQFGCKVAIIMASG 103
Cdd:smart00881  78 APDAIDEAIEAGIKGIVVITEG 99
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 740-889 1.26e-12

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 66.95  E-value: 1.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 740 VMLRPILPEDEPKHLDFDNsltDED--RYKRYFGVRSRMTHEEMAVLTQIDYAREMAFIATIRDENGEeeTLGAVRAS-I 816
Cdd:COG1670     8 LRLRPLRPEDAEALAELLN---DPEvaRYLPGPPYSLEEARAWLERLLADWADGGALPFAIEDKEDGE--LIGVVGLYdI 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178847744 817 DPDNTEAEFAMAVRSSHQGIGIGKLLLEKLINYYRTT-GTQVLTGFTMFENRNMASLAKSLGFTVTFDMEEHLI 889
Cdd:COG1670    83 DRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALV 156
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 777-878 1.67e-07

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 50.59  E-value: 1.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 777 THEEMAVLTQIDYAREMAFIATIRDEngeeETLGAVRASIDPDNTE--AEFAMAVRSSHQGIGIGKLLLEKLINYYRTTG 854
Cdd:pfam00583  17 PDEPLDLLEDWDEDASEGFFVAEEDG----ELVGFASLSIIDDEPPvgEIEGLAVAPEYRGKGIGTALLQALLEWARERG 92

                          90       100
                  ....*....|....*....|....
gi 2178847744 855 TQVLTGFTMFENRNMASLAKSLGF 878
Cdd:pfam00583  93 CERIFLEVAADNLAAIALYEKLGF 116
 
Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-717 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 909.50  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744   1 MSQRTLHTLFKPGSIAVIGASNSHKRAGNVVMKNLLSGGFAGPIMPVTPKYHAVMGVLAYPNIESLPIKPDLAIICTRAS 80
Cdd:COG1042     1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744  81 SVPAIVETLAQFGCKVAIIMASGMAdELNEQGENLLELTQGNARRYGMRILGPNSLGMMLPPQGLNASLAHAGALPGKIA 160
Cdd:COG1042    81 TVPDVVEECGEKGVKAAVVISAGFA-ETGEEGAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 161 FVSQSAAICTTVLDWANNKGIGFSSFISLGDATDIDFDELLDFLGRDSRTSAIMLYIDSVNEKRHFLSAARAAARHKPIL 240
Cdd:COG1042   160 LVSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVV 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 241 VIKSGRSAEGGNAAKLHTGGIAGNDAVYEAAFRRAGMLRVTDLVELFAALESLAHLNPLNGERLCILSNGGGPAVLAVDE 320
Cdd:COG1042   240 VLKSGRSEAGARAAASHTGALAGSDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 321 LVLKGGKLAQLSEATLDKLSQLLPSTWSGQNPVDIIGDAGAERYSQALSVLMDSDELDAILVLHSPSALGESVTIADALI 400
Cdd:COG1042   320 LEDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALI 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 401 ETVKQHSKrnrvSILTNWSGEDAAYRARKHFSKAGIPTYRTPEGAVRAFMHMVEYRRNQKLLQEVPQsiPDSIPTDSATA 480
Cdd:COG1042   400 EAAKGSGK----PVLASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA--SEDFDPDRERA 473

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 481 RSLLQQAIAKGKRVLETHDARNILNAYGLDTIDTWYAKDAAEAVAIADKAGYPVALKVQSPDILHKSDVHGVMLNLTSAN 560
Cdd:COG1042   474 RAIIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAE 553

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 561 EVNQAAAAIVERVHASNPAASVEGMIVQKMAltAGAQELRVAVISDPVFGPAIMLGEGGSEWEPTRDAAVALPPLNMALA 640
Cdd:COG1042   554 AVRAAFEEILARVRAARPDARIDGVLVQPMV--PGGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALA 631

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2178847744 641 RYMVIQALKTQKIRDRHLPQGLDMRALCLMLTQISQLIIDCPEIESLDLNPVLAAGEKITLLDVNLRLNPEVTDNAG 717
Cdd:COG1042   632 REMIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPPAPR 708
AcCoA-syn-alpha TIGR02717
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ...
 6-456 3.34e-162

acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.


Pssm-ID: 131764 [Multi-domain]  Cd Length: 447  Bit Score: 481.04  E-value: 3.34e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744   6 LHTLFKPGSIAVIGASNSHKRAGNVVMKNLLSGGFAGPIMPVTPKYHAVMGVLAYPNIESLPIKPDLAIICTRASSVPAI 85
Cdd:TIGR02717   1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744  86 VETLAQFGCKVAIIMASGMAdELNEQGENLLELTQGNARRYGMRILGPNSLGMMLPPQGLNASLAHAGALPGKIAFVSQS 165
Cdd:TIGR02717  81 VEECGEKGVKGAVVITAGFK-EVGEEGAELEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTMPKKGGIAFISQS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 166 AAICTTVLDWANNKGIGFSSFISLGDATDIDFDELLDFLGRDSRTSAIMLYIDSVNEKRHFLSAARAAARHKPILVIKSG 245
Cdd:TIGR02717 160 GALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKFLKTAREISKKKPIVVLKSG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 246 RSAEGGNAAKLHTGGIAGNDAVYEAAFRRAGMLRVTDLVELFAALESLAHLNPLNGERLCILSNGGGPAVLAVDELVLKG 325
Cdd:TIGR02717 240 TSEAGAKAASSHTGALAGSDEAYDAAFKQAGVIRADSIEELFDLARLLSNQPLPKGNRVAIITNAGGPGVIATDACEENG 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 326 GKLAQLSEATLDKLSQLLPSTWSGQNPVDIIGDAGAERYSQALSVLMDSDELDAILVLHSPSALGESVTIADALIETVKQ 405
Cdd:TIGR02717 320 LELAELSEATKNKLRNILPPEASIKNPVDVLGDATPERYAKALKTVAEDENVDGVVVVLTPTAMTDPEEVAKGIIEGAKK 399

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2178847744 406 HskrNRVSILTNWSGEDAAYRARKHFSKAGIPTYRTPEGAVRAFMHMVEYR 456
Cdd:TIGR02717 400 S---NEKPVVAGFMGGKSVDPAKRILEENGIPNYTFPERAVKALSALYRYA 447
ATP-grasp_5 pfam13549
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ...
 486-708 1.51e-91

ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.


Pssm-ID: 463918 [Multi-domain]  Cd Length: 221  Bit Score: 288.61  E-value: 1.51e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 486 QAIAKGKRVLETHDARNILNAYGLDTIDTWYAKDAAEAVAIADKAGYPVALKVQSPDILHKSDVHGVMLNLTSANEVNQA 565
Cdd:pfam13549   1 KALAEGRTVLTEPEAKALLAAYGIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 566 AAAIVERVHASNPAASVEGMIVQKMALtaGAQELRVAVISDPVFGPAIMLGEGGSEWEPTRDAAVALPPLNMALARYMvI 645
Cdd:pfam13549  81 YEEILERVRRYRPDARIEGVLVQPMAP--GGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREM-I 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178847744 646 QALKTQKIRDRHLPQ-GLDMRALCLMLTQISQLIIDCPEIESLDLNPVLAAGEKITLLDVNLRL 708
Cdd:pfam13549 158 RRTRAYKLLKGYRGEpPADLDALEDVLVRVSQLVIDFPEIRELDINPLLADEDGVVALDARIRL 221
Succ_CoA_lig pfam13607
Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from ...
 156-293 1.06e-60

Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from Succinyl-CoA ligase alpha subunit and other related enzymes. A conserved histidine is involved in phosphoryl transfer.


Pssm-ID: 433345 [Multi-domain]  Cd Length: 138  Bit Score: 202.31  E-value: 1.06e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 156 PGKIAFVSQSAAICTTVLDWANNKGIGFSSFISLGDATDIDFDELLDFLGRDSRTSAIMLYIDSVNEKRHFLSAARAAAR 235
Cdd:pfam13607   1 PGNIALVSQSGALGAALLDWARSRGIGFSKFVSLGNEADVDFADLLEYLADDPETRVILLYLEGIRDGRRFLRAARRAAR 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2178847744 236 HKPILVIKSGRSAEGGNAAKLHTGGIAGNDAVYEAAFRRAGMLRVTDLVELFAALESL 293
Cdd:pfam13607  81 RKPVVVLKAGRSEAGARAAASHTGALAGSDAVYDAAFRQAGVIRVDDLEELFDAAEAL 138
CoA_binding_2 pfam13380
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 14-141 9.02e-28

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 433162 [Multi-domain]  Cd Length: 116  Bit Score: 108.40  E-value: 9.02e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744  14 SIAVIGASNSHKRAGNVVMKNLLSGGFagPIMPVTPKYHAVMGVLAYPNIESLPIKPDLAIICTRASSVPAIVETLAQFG 93
Cdd:pfam13380   2 TIAVVGASPNPGRPGYKVARYLLEHGY--PVIPVNPKAKEILGEPVYPSLADPPEPVDLVDVFRPPEAVPEIVEEALALG 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2178847744  94 CKVAIIMASGMADELNEQgenlleltqgnARRYGMRILGPNSLGMMLP 141
Cdd:pfam13380  80 AKAVWLQPGIENEEAAAI-----------ARAAGIRVVGDRCLGVEHP 116
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 9-103 3.50e-20

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 86.02  E-value: 3.50e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744    9 LFKPG-SIAVIGASNSHKRAGNVVMKNLLSGG--FAGPIMP--VTPKYHavmGVLAYPNIESLPIK--PDLAIICTRASS 81
Cdd:smart00881   1 LLNPNtSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYPgkVGPKVD---GVPVYDSVAEAPEEtgVDVAVIFVPAEA 77

                           90       100
                   ....*....|....*....|..
gi 2178847744   82 VPAIVETLAQFGCKVAIIMASG 103
Cdd:smart00881  78 APDAIDEAIEAGIKGIVVITEG 99
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 740-889 1.26e-12

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 66.95  E-value: 1.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 740 VMLRPILPEDEPKHLDFDNsltDED--RYKRYFGVRSRMTHEEMAVLTQIDYAREMAFIATIRDENGEeeTLGAVRAS-I 816
Cdd:COG1670     8 LRLRPLRPEDAEALAELLN---DPEvaRYLPGPPYSLEEARAWLERLLADWADGGALPFAIEDKEDGE--LIGVVGLYdI 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178847744 817 DPDNTEAEFAMAVRSSHQGIGIGKLLLEKLINYYRTT-GTQVLTGFTMFENRNMASLAKSLGFTVTFDMEEHLI 889
Cdd:COG1670    83 DRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALV 156
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
739-890 2.97e-11

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 62.70  E-value: 2.97e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 739 EVMLRPILPEDEPKHLDFDNSLTDEdRYKRYFGVRsrMTHEEMAV-LTQIDYAREMAFIAtirDENGEeeTLGAVRASI- 816
Cdd:COG1247     1 EMTIRPATPEDAPAIAAIYNEAIAE-GTATFETEP--PSEEEREAwFAAILAPGRPVLVA---EEDGE--VVGFASLGPf 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2178847744 817 ---DPDNTEAEFAMAVRSSHQGIGIGKLLLEKLINYYRTTGTQVLTGFTMFENRNMASLAKSLGFTVTFDMEEHLIK 890
Cdd:COG1247    73 rprPAYRGTAEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGFEEVGTLPEVGFK 149
YccU COG1832
Predicted CoA-binding protein [General function prediction only];
14-96 1.58e-10

Predicted CoA-binding protein [General function prediction only];


Pssm-ID: 441437 [Multi-domain]  Cd Length: 138  Bit Score: 59.76  E-value: 1.58e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744  14 SIAVIGASNSHKRAGNVVMKNLLSGGFAgpIMPVTPKYHAVMGVLAYPNIESLPIKPDLAIICTRASSVPAIVETLAQFG 93
Cdd:COG1832    18 TIAVVGLSPNPERPSYYVAKYLQRHGYR--VIPVNPGAKEILGEKVYASLADIPEPVDIVDVFRRSEAVPEIVDEAIAIG 95


                  ...
gi 2178847744  94 CKV 96
Cdd:COG1832    96 AKV 98
SucD COG0074
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ...
 123-276 1.87e-10

Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439844 [Multi-domain]  Cd Length: 288  Bit Score: 62.77  E-value: 1.87e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 123 ARRYGMRILGPNSLGMMLPPQ---GLNASLAHAgalPGKIAFVSQSAAICTTVLDWANNKGIGFSSFISLGdaTD----I 195
Cdd:COG0074   111 AKAKGTRLIGPNCPGIITPGEcklGIMPGHIFK---PGRVGIVSRSGTLTYEAVWQLTQAGLGQSTCVGIG--GDpiigT 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 196 DFDELLDFLGRDSRTSAIMLY--IDSVNEKRhflsAAR--AAARHKPILVIKSGRSA-EG---GNAAKLHTGGiAGNDAV 267
Cdd:COG0074   186 SFIDVLELFEEDPETEAIVMIgeIGGSAEEE----AAEyiKENMTKPVVAYIAGRTApPGkrmGHAGAIISGG-KGTAES 260


                  ....*....
gi 2178847744 268 YEAAFRRAG 276
Cdd:COG0074   261 KIEALEAAG 269
CoA_binding pfam02629
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 10-103 4.41e-10

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 396961 [Multi-domain]  Cd Length: 97  Bit Score: 57.22  E-value: 4.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744  10 FKPGSIAVIGASNSHKRAGNVVMKNLLSGGFAGpIMPVTPK--YHAVMGVLAYPNIESLP--IKPDLAIICTRASSVPAI 85
Cdd:pfam02629   1 DKDTKVIVIGAGGLGIQGLNYHFIQMLGYGIKM-VFGVNPGkgGTEILGIPVYNSVDELEekTGVDVAVITVPAPFAQEA 79

                          90
                  ....*....|....*...
gi 2178847744  86 VETLAQFGCKVAIIMASG 103
Cdd:pfam02629  80 IDELVDAGIKGIVNITPG 97
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 777-878 1.67e-07

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 50.59  E-value: 1.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 777 THEEMAVLTQIDYAREMAFIATIRDEngeeETLGAVRASIDPDNTE--AEFAMAVRSSHQGIGIGKLLLEKLINYYRTTG 854
Cdd:pfam00583  17 PDEPLDLLEDWDEDASEGFFVAEEDG----ELVGFASLSIIDDEPPvgEIEGLAVAPEYRGKGIGTALLQALLEWARERG 92

                          90       100
                  ....*....|....*....|....
gi 2178847744 855 TQVLTGFTMFENRNMASLAKSLGF 878
Cdd:pfam00583  93 CERIFLEVAADNLAAIALYEKLGF 116
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 810-896 1.68e-06

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 46.96  E-value: 1.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 810 GAVRASIDPDNTEAE-FAMAVRSSHQGIGIGKLLLEKLINYYRTTGTQVLTGFTMFENRNMASLAKSLGFTVT--FDMEE 886
Cdd:COG0456     1 GFALLGLVDGGDEAEiEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGFEEVgeRPNYY 80

                          90
                  ....*....|
gi 2178847744 887 HLIKMHMELP 896
Cdd:COG0456    81 GDDALVMEKE 90
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 805-895 6.06e-06

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 46.59  E-value: 6.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 805 EEETLGAVRASIDPDNTeAEFA-MAVRSSHQGIGIGKLLLEKLINYYRTTGTQVLTGFTMFENRNMASLAKSLGFTVTFD 883
Cdd:COG0454    42 KGEPIGFAGLRRLDDKV-LELKrLYVLPEYRGKGIGKALLEALLEWARERGCTALELDTLDGNPAAIRFYERLGFKEIER 120

                          90
                  ....*....|...
gi 2178847744 884 MEEHLI-KMHMEL 895
Cdd:COG0454   121 YVAYVGgEFEKEL 133
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 740-879 2.06e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 45.03  E-value: 2.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 740 VMLRPILPEDEPkhlDFDNSLTDEDRykRYFGVRSRMTHEE-----MAVLTQIDYAREMAFIATIRDENgeeeTLGAVR- 813
Cdd:pfam13302   2 LLLRPLTEEDAE---ALFELLSDPEV--MRYGVPWPLTLEEarewlARIWAADEAERGYGWAIELKDTG----FIGSIGl 72

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2178847744 814 ASIDPDNTEAEFAMAVRSSHQGIGIGKLLLEKLINY-YRTTGTQVLTGFTMFENRNMASLAKSLGFT 879
Cdd:pfam13302  73 YDIDGEPERAELGYWLGPDYWGKGYATEAVRALLEYaFEELGLPRLVARIDPENTASRRVLEKLGFK 139
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 805-880 4.28e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 42.83  E-value: 4.28e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2178847744 805 EEETLGAVRASIDPDNTE-AEFAMAVRSSHQGIGIGKLLLEKLINYYRTTGtqvLTGFTMFENRNMASLAKSLGFTV 880
Cdd:pfam13508  11 DGKIVGFAALLPLDDEGAlAELRLAVHPEYRGQGIGRALLEAAEAAAKEGG---IKLLELETTNRAAAFYEKLGFEE 84
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
788-881 2.76e-03

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 38.91  E-value: 2.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2178847744 788 DYAREMAFIATIrdengEEETLGAVRASIDPDNTEAEFA----MAVRSSHQGIGIGKLLLEKLINYYRTTGTQVLTGFTm 863
Cdd:COG3153    35 DPAAGLSLVAED-----DGEIVGHVALSPVDIDGEGPALllgpLAVDPEYRGQGIGRALMRAALEAARERGARAVVLLG- 108

                          90
                  ....*....|....*...
gi 2178847744 864 feNRNMASLAKSLGFTVT 881
Cdd:COG3153   109 --DPSLLPFYERFGFRPA 124
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
826-890 2.90e-03

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 37.58  E-value: 2.90e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2178847744 826 AMAVRSSHQGIGIGKLLLEKLINYYRTTGTQVLTGFTMFENRNMASLAKSLGFTVTFDMEEHLIK 890
Cdd:COG3393    20 GVYTHPEYRGRGLASALVAALAREALARGARTPFLYVDADNPAARRLYERLGFRPVGEYATVLFR 84
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 805-881 7.47e-03

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 37.66  E-value: 7.47e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2178847744 805 EEETLGAVRASIDPDNTeAEFA-MAVRSSHQGIGIGKLLLEKLINYYRTTGTQVLTGFTmfeNRNMASLAKSLGFTVT 881
Cdd:COG1246    36 DGEIVGCAALHPLDEDL-AELRsLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLT---TSAAIHFYEKLGFEEI 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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