NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2179459699|ref|WP_234823411|]
View 

TetR/AcrR family transcriptional regulator [Bacillus altitudinis]

Protein Classification

TetR/AcrR family transcriptional regulator( domain architecture ID 11442015)

TetR/AcrR family transcriptional regulator may control genes involved in one of a variety of processes including antibiotic production, osmotic stress response, efflux pump expression, and multidrug resistance

CATH:  1.10.10.60|1.10.357.10
Gene Ontology:  GO:0003700|GO:0003677|GO:0006355
PubMed:  23602932
SCOP:  4000333

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
7-100 1.08e-12

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


:

Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 62.99  E-value: 1.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2179459699   7 DPRILRTRQLIVDSFLSLASEKDFNHITVRDITEKATINRATFYAHFDDKFDLLHSTI---TNTFTDKLKKRLNDHDGfn 83
Cdd:COG1309     1 RRRREATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLerlLEELLAALEEALAAEDP-- 78

                          90
                  ....*....|....*..
gi 2179459699  84 EKVIANIFLAMCDHHKE 100
Cdd:COG1309    79 RERLRALLRAYLEFLAE 95
 
Name Accession Description Interval E-value
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
7-100 1.08e-12

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 62.99  E-value: 1.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2179459699   7 DPRILRTRQLIVDSFLSLASEKDFNHITVRDITEKATINRATFYAHFDDKFDLLHSTI---TNTFTDKLKKRLNDHDGfn 83
Cdd:COG1309     1 RRRREATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLerlLEELLAALEEALAAEDP-- 78

                          90
                  ....*....|....*..
gi 2179459699  84 EKVIANIFLAMCDHHKE 100
Cdd:COG1309    79 RERLRALLRAYLEFLAE 95
TetR_N pfam00440
Bacterial regulatory proteins, tetR family;
17-61 9.38e-06

Bacterial regulatory proteins, tetR family;


Pssm-ID: 425684 [Multi-domain]  Cd Length: 47  Bit Score: 41.24  E-value: 9.38e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2179459699  17 IVDSFLSLASEKDFNHITVRDITEKATINRATFYAHFDDKFDLLH 61
Cdd:pfam00440   1 ILDAARELFAERGYDATTVREIAKRAGVSKGALYRYFGSKEELLE 45
PRK11202 PRK11202
HTH-type transcriptional repressor FabR;
11-55 3.95e-04

HTH-type transcriptional repressor FabR;


Pssm-ID: 236881 [Multi-domain]  Cd Length: 203  Bit Score: 39.60  E-value: 3.95e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2179459699  11 LRTRQLIVDS-FLSLASEKDFNHITVRDITEKATINRATFYAHFDD 55
Cdd:PRK11202   10 EKTRRALIDAaFSQLSAERSFSSLSLREVAREAGIAPTSFYRHFRD 55
 
Name Accession Description Interval E-value
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
7-100 1.08e-12

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 62.99  E-value: 1.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2179459699   7 DPRILRTRQLIVDSFLSLASEKDFNHITVRDITEKATINRATFYAHFDDKFDLLHSTI---TNTFTDKLKKRLNDHDGfn 83
Cdd:COG1309     1 RRRREATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLerlLEELLAALEEALAAEDP-- 78

                          90
                  ....*....|....*..
gi 2179459699  84 EKVIANIFLAMCDHHKE 100
Cdd:COG1309    79 RERLRALLRAYLEFLAE 95
TetR_N pfam00440
Bacterial regulatory proteins, tetR family;
17-61 9.38e-06

Bacterial regulatory proteins, tetR family;


Pssm-ID: 425684 [Multi-domain]  Cd Length: 47  Bit Score: 41.24  E-value: 9.38e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2179459699  17 IVDSFLSLASEKDFNHITVRDITEKATINRATFYAHFDDKFDLLH 61
Cdd:pfam00440   1 ILDAARELFAERGYDATTVREIAKRAGVSKGALYRYFGSKEELLE 45
PRK11202 PRK11202
HTH-type transcriptional repressor FabR;
11-55 3.95e-04

HTH-type transcriptional repressor FabR;


Pssm-ID: 236881 [Multi-domain]  Cd Length: 203  Bit Score: 39.60  E-value: 3.95e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2179459699  11 LRTRQLIVDS-FLSLASEKDFNHITVRDITEKATINRATFYAHFDD 55
Cdd:PRK11202   10 EKTRRALIDAaFSQLSAERSFSSLSLREVAREAGIAPTSFYRHFRD 55
PRK09975 PRK09975
DNA-binding transcriptional regulator EnvR; Provisional
 11-59 1.29e-03

DNA-binding transcriptional regulator EnvR; Provisional


Pssm-ID: 182177 [Multi-domain]  Cd Length: 213  Bit Score: 38.18  E-value: 1.29e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2179459699  11 LRTRQLIVDSFLSLASEKDFNHITVRDITEKATINRATFYAHFDDKFDL 59
Cdd:PRK09975   10 LKTRQELIETAIAQFALRGVSNTTLNDIADAANVTRGAIYWHFENKTQL 58
PRK10668 PRK10668
DNA-binding transcriptional repressor AcrR; Provisional
 11-61 4.90e-03

DNA-binding transcriptional repressor AcrR; Provisional


Pssm-ID: 182632 [Multi-domain]  Cd Length: 215  Bit Score: 36.52  E-value: 4.90e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2179459699  11 LRTRQLIVDSFLSLASEKDFNHITVRDITEKATINRATFYAHFDDKFDLLH 61
Cdd:PRK10668   10 QETRQHILDAALRLFSQQGVSATSLADIAKAAGVTRGAIYWHFKNKSDLFS 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH