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Conserved domains on  [gi|2182224429|ref|WP_235604770|]
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TniQ family protein [Sulfitobacter sp. EhC04]

Protein Classification

TniQ family protein( domain architecture ID 5146)

TniQ family protein similar to Vibrio cholerae TniQ protein that is part of the RNA-guided DNA integration in type I-F CRISPR-Cas system; TniQ binds to the Cascade complex and recruits the core TnsABC machinery for transposition, thus playing an essential role in transposition

Gene Ontology:  GO:0032196|GO:0015074
PubMed:  8594337|31900425

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TniQ super family cl05839
TniQ; This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is ...
 10-132 1.59e-08

TniQ; This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.


The actual alignment was detected with superfamily member pfam06527:

Pssm-ID: 461938  Cd Length: 143  Bit Score: 51.05  E-value: 1.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2182224429  10 TSLLSRLAARNGaISMQRFCGDIAFPIDPLFRGE------KVAIEQLAQLAGCDVGALE---------RVSIRHVGKGHF 74
Cdd:pfam06527  13 SSYLARLARANG-VSPKTLLRDLFGGSGRSLADLdlplnlPALLARLAALTGLDPERLEamtllpyylRSVLVPPGGRIR 91

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2182224429  75 RLRDEFASLQSFQRTRIRVCPECtrsempsaAESWRVP--RRLQWKFSSIRSCPEHGSML 132
Cdd:pfam06527  92 RRLGLAISSRGLRREGLRFCPLC--------LAEDGVPyyWRLLWQLPLVTVCPKHGCRL 143
 
Name Accession Description Interval E-value
TniQ pfam06527
TniQ; This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is ...
 10-132 1.59e-08

TniQ; This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.


Pssm-ID: 461938  Cd Length: 143  Bit Score: 51.05  E-value: 1.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2182224429  10 TSLLSRLAARNGaISMQRFCGDIAFPIDPLFRGE------KVAIEQLAQLAGCDVGALE---------RVSIRHVGKGHF 74
Cdd:pfam06527  13 SSYLARLARANG-VSPKTLLRDLFGGSGRSLADLdlplnlPALLARLAALTGLDPERLEamtllpyylRSVLVPPGGRIR 91

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2182224429  75 RLRDEFASLQSFQRTRIRVCPECtrsempsaAESWRVP--RRLQWKFSSIRSCPEHGSML 132
Cdd:pfam06527  92 RRLGLAISSRGLRREGLRFCPLC--------LAEDGVPyyWRLLWQLPLVTVCPKHGCRL 143
 
Name Accession Description Interval E-value
TniQ pfam06527
TniQ; This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is ...
 10-132 1.59e-08

TniQ; This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.


Pssm-ID: 461938  Cd Length: 143  Bit Score: 51.05  E-value: 1.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2182224429  10 TSLLSRLAARNGaISMQRFCGDIAFPIDPLFRGE------KVAIEQLAQLAGCDVGALE---------RVSIRHVGKGHF 74
Cdd:pfam06527  13 SSYLARLARANG-VSPKTLLRDLFGGSGRSLADLdlplnlPALLARLAALTGLDPERLEamtllpyylRSVLVPPGGRIR 91

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2182224429  75 RLRDEFASLQSFQRTRIRVCPECtrsempsaAESWRVP--RRLQWKFSSIRSCPEHGSML 132
Cdd:pfam06527  92 RRLGLAISSRGLRREGLRFCPLC--------LAEDGVPyyWRLLWQLPLVTVCPKHGCRL 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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