|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
8-883 |
0e+00 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 587.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 8 DALLADLPRDGRGRLKVFLGAAPGVGKTYAMLQAAHTQLRQGVRLIAGVVETHGRAETEALLSGLPQQPLLRSEYRGVML 87
Cdd:PRK10490 11 DRLLEQTAEPHRGKLKIFFGACAGVGKTYAMLQEAQRLRAQGLDVLVGVVETHGRKETAALLEGLTVLPPKRIHHRGRHI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 88 EEMDLDGLLAAKPKLVLVDELAHSNAPGSRHEKRWQDIQELLAAGINVFTTVNVQHLESLNDQVRGITGVHVRETLPDWV 167
Cdd:PRK10490 91 SEFDLDAALARRPALILMDELAHSNAPGSRHPKRWQDVEELLEAGIDVFTTVNVQHLESLNDVVGGVTGIQVRETVPDPF 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 168 LQEADELLLIDLPSRELLERLRDGKVYVPEQARAAIDAFFTQTNLMALRELAMQTAAAHVDDDL-AQGYRQLGQAAPAVR 246
Cdd:PRK10490 171 FDAADEVVLVDLPPDDLRQRLNEGKVYIAGQAERAIEHFFRKGNLIALRELALRRTADRVDDQMrAWRDHQGEEKVWHTR 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 247 GRLLVGVDGDAQAERLVRHASRVAQRRHLPWSLVHIDNGR--ARDEQSRLRLQNAQQLAERLGGEVVLLRAGEVAKTLIQ 324
Cdd:PRK10490 251 DAILLCIGHNTGSEKLVRTAARLAARLGSVWHAVYVETPRlhRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVLR 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 325 HAAERRASLVLVGQ-SRMRWRRRlfgGGLAARLLRNARGLEINV--LDSDDMPAPPRLPDVRGLV--W----FDYGLAVV 395
Cdd:PRK10490 331 YAREHNLGKIIIGRrASRRWWRR---ESFADRLARLGPDLDLVIvaLDEPPARAIAKAPDSRPFKekWrvqiQGCLVAIA 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 396 ATIVAAALAWAVASVLPLPNISLVFLAAVLLVGVRSSLGPSLVCAALSFLTYDFLFIPPNFSFSIQREEDVLTLLFFLLM 475
Cdd:PRK10490 408 LCALITLIAMQWLPAFDAANLVMLYLLGVVVVALFYGRWPSVVATVINVASFDLFFVAPRGTLAVSDVQYLLTFAVMLTV 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 476 AALTGNLAARQRRQLQALRDTQEETSELLDLSRKLTAATDRQAVISAAAHHLQGWSDLELCLLNRDGQGGWkVETGAALN 555
Cdd:PRK10490 488 GLVIGNLTAGVRYQARVARYREQRTRHLYEMSKALAVGLSPEDIAATSEHFLASTFQARSQLLLPDDNGKL-QPLTHDQG 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 556 LTEAERAAADWAWQHDQPAGMGTGTLPFGRWWWWPLSGEEGPLGLLGVSPKPGLELS-GQRRRLLTALSQPLAQALARAQ 634
Cdd:PRK10490 567 MTPWDDAIARWSFDKGQPAGAGTDTLPGVPYQILPLKSAQKTYGLLAVEPGNLRQLMiPEQQRLLETFTLLIANALERLT 646
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 635 LAQELESARLHGETEQLRSALLASVSHDLRTPLTSMRGSIDSL---LALgEAIPL-----EDRRELLEGTrdeaerldRY 706
Cdd:PRK10490 647 LTASEEQARLASEREQLRNALLAALSHDLRTPLTVLFGQAEILtldLAS-EGSPHarqasEIRQQVLNTT--------RL 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 707 IQNLLDMTRLGHGALKLARDWVSPGDIVGSALGRLRAVLAPLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAH 786
Cdd:PRK10490 718 VNNLLDMARIQSGGFNLRKEWLTLEEVVGSALQMLEPGLSGHPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQ 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 787 GRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFytaARGDRGGQ--GTGLGLAICQGMVGAHGGHIRVEDGIEGrG 864
Cdd:PRK10490 798 AEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKF---ARGNKESAipGVGLGLAICRAIVEVHGGTIWAENRPEG-G 873
|
890
....*....|....*....
gi 2184758710 865 TCISLFLPLPTQPGPEREP 883
Cdd:PRK10490 874 ACFRVTLPLETPPELEEFH 892
|
|
| KdpD |
pfam02702 |
Osmosensitive K+ channel His kinase sensor domain; This is a family of KdpD sensor kinase ... |
18-227 |
1.31e-124 |
|
Osmosensitive K+ channel His kinase sensor domain; This is a family of KdpD sensor kinase proteins that regulate the kdpFABC operon responsible for potassium transport. The aligned region corresponds to the N-terminal cytoplasmic part of the protein which functions as the sensor domain responsible for sensing turgor pressure. It recognizes C-di-AMP and K+ (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 460656 [Multi-domain] Cd Length: 210 Bit Score: 374.06 E-value: 1.31e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 18 GRGRLKVFLGAAPGVGKTYAMLQAAHTQLRQGVRLIAGVVETHGRAETEALLSGLPQQPLLRSEYRGVMLEEMDLDGLLA 97
Cdd:pfam02702 1 RRGRLKIFLGAAPGVGKTYAMLQEAHRLKKRGVDVVIGYVETHGRPETEALLEGLEVIPRREIEYRGRTLEEMDLDAILA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 98 AKPKLVLVDELAHSNAPGSRHEKRWQDIQELLAAGINVFTTVNVQHLESLNDQVRGITGVHVRETLPDWVLQEADELLLI 177
Cdd:pfam02702 81 RRPEVVLVDELAHTNAPGSRHPKRWQDVEELLDAGIDVYTTVNIQHLESLNDVVEQITGVRVRETVPDSVLDRADEVELV 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2184758710 178 DLPSRELLERLRDGKVYVPEQARAAIDAFFTQTNLMALRELAMQTAAAHV 227
Cdd:pfam02702 161 DLTPEELLERLKEGKVYPPEKAERALKNFFRKGNLTALRELALRRVADRV 210
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
647-873 |
1.57e-75 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 246.36 E-value: 1.57e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 647 ETEQLRSALLASVSHDLRTPLTSMRGSIDsLLALGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLARD 726
Cdd:COG2205 11 ELERLKSEFLANVSHELRTPLTSILGAAE-LLLDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESGKLSLELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 727 WVSPGDIVGSALGRLRAVLAP--LQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAV 804
Cdd:COG2205 90 PVDLAELLEEAVEELRPLAEEkgIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREGDGVRISV 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2184758710 805 ADEGPGIPEDERAKIFDMFYTAARgDRGGQGTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCISLFLPL 873
Cdd:COG2205 170 SDNGPGIPEEELERIFERFYRGDN-SRGEGGTGLGLAIVKRIVEAHGGTIWVES-EPGGGTTFTVTLPL 236
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
647-873 |
6.78e-62 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 214.80 E-value: 6.78e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 647 ETEQLRSALLASVSHDLRTPLTSMRGSIDsLLALGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLARD 726
Cdd:COG5002 160 RLEQMRREFVANVSHELRTPLTSIRGYLE-LLLDGAADDPEERREYLEIILEEAERLSRLVNDLLDLSRLESGELKLEKE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 727 WVSPGDIVGSALGRLRAVLA--PLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAV 804
Cdd:COG5002 239 PVDLAELLEEVVEELRPLAEekGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQVRISV 318
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 805 ADEGPGIPEDERAKIFDMFYTAARGD-RGGQGTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCISLFLPL 873
Cdd:COG5002 319 RDTGIGIPEEDLPRIFERFYRVDKSRsRETGGTGLGLAIVKHIVEAHGGRIWVES-EPGKGTTFTITLPL 387
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
552-874 |
1.15e-57 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 200.90 E-value: 1.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 552 AALNLTEAERAAADWAWQHDQPAGMGTGTLPFGRWWWWPLSGEEGPLGLLGVSPKPGLELSGQRRRLLTALSQPLAQALA 631
Cdd:COG0642 16 LLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 632 RAQLAQELESArlhgetEQLRSALLASVSHDLRTPLTSMRGSIDSLLALGEaiplEDRRELLEGTRDEAERLDRYIQNLL 711
Cdd:COG0642 96 LLALLLLLEEA------NEAKSRFLANVSHELRTPLTAIRGYLELLLEELD----EEQREYLETILRSADRLLRLINDLL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 712 DMTRLGHGALKLARDWVSPGDIVGSALGRLRAVLAP--LQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRL 789
Cdd:COG0642 166 DLSRLEAGKLELEPEPVDLAELLEEVVELFRPLAEEkgIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 790 QVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTaARGDRGGQGTGLGLAICQGMVGAHGGHIRVEDGiEGRGTCISL 869
Cdd:COG0642 246 TVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFR-TDPSRRGGGTGLGLAIVKRIVELHGGTIEVESE-PGKGTTFTV 323
|
....*
gi 2184758710 870 FLPLP 874
Cdd:COG0642 324 TLPLA 328
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
515-873 |
5.35e-44 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 163.43 E-value: 5.35e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 515 DRQAVISAAAHHLQGWSDLELCLLNRDGQGGWKVETGAALNLTEAERAAADWAWQHDQPAGMGTGTLPFGRWWWWPLSGE 594
Cdd:COG4191 2 LRLLLLLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 595 EGPLGLLGVSPKPGLELSGQRRRLLTALSQPLAQALARAQLAQELESARlhgetEQLRSA--------LLASVSHDLRTP 666
Cdd:COG4191 82 LGLLLLLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRELQ-----EQLVQSeklaalgeLAAGIAHEINNP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 667 LTSMRGSIDSLLA-LGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGhgalKLARDWVSPGDIVGSALGRLRAVL 745
Cdd:COG4191 157 LAAILGNAELLRRrLEDEPDPEELREALERILEGAERAAEIVRSLRAFSRRD----EEEREPVDLNELIDEALELLRPRL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 746 --APLQVHTDVPAQLPLLYVHAALIEQALVNVLENA--ARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFD 821
Cdd:COG4191 233 kaRGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAidAMEEGEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFE 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 2184758710 822 MFYTAargDRGGQGTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCISLFLPL 873
Cdd:COG4191 313 PFFTT---KPVGKGTGLGLSISYGIVEKHGGRIEVES-EPGGGTTFTITLPL 360
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
655-873 |
8.45e-41 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 155.51 E-value: 8.45e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 655 LLASVSHDLRTPLTSMRGSIDSLLALGEAIPLEDRRELLEGTR---DEAERLDRYIQNLLDMTRLGhgalKLARDWVSPG 731
Cdd:COG5000 204 LARRIAHEIKNPLTPIQLSAERLRRKLADKLEEDREDLERALDtiiRQVDRLKRIVDEFLDFARLP----EPQLEPVDLN 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 732 DIVGSALGRLRAVLAP--LQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGP 809
Cdd:COG5000 280 ELLREVLALYEPALKEkdIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGP 359
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2184758710 810 GIPEDERAKIFDMFYTAARgdrggQGTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCISLFLPL 873
Cdd:COG5000 360 GIPEEVLERIFEPFFTTKP-----KGTGLGLAIVKKIVEEHGGTIELES-RPGGGTTFTIRLPL 417
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
647-880 |
6.88e-39 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 148.46 E-value: 6.88e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 647 ETEQLRSA--LLASVSHDLRTPLTSMRGSIDsLLAlgEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKla 724
Cdd:COG3852 128 RAEKLAAVgeLAAGLAHEIRNPLTGIRGAAQ-LLE--RELPDDELREYTQLIIEEADRLNNLVDRLLSFSRPRPPERE-- 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 725 rdWVSPGDIVGSALGRLRAVLAP-LQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVV------- 796
Cdd:COG3852 203 --PVNLHEVLERVLELLRAEAPKnIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRVErqvtlgg 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 797 ---DEQLFFAVADEGPGIPEDERAKIFDMFYTAargdrGGQGTGLGLAICQGMVGAHGGHIRVEdGIEGRGTCISLFLPL 873
Cdd:COG3852 281 lrpRLYVRIEVIDNGPGIPEEILDRIFEPFFTT-----KEKGTGLGLAIVQKIVEQHGGTIEVE-SEPGKGTTFRIYLPL 354
|
....*..
gi 2184758710 874 PTQPGPE 880
Cdd:COG3852 355 EQAEEEP 361
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
482-872 |
3.60e-37 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 146.85 E-value: 3.60e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 482 LAARQRRQLQALRDTQEETSELLDLSRKLTAATDRQAVISAAAHHLQGWSDLELCLLNRDGQGGWKVETGAALNLTEAER 561
Cdd:COG4251 107 LLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 562 AAADWAWQHDQPAGMGTGTLPFGRWWWWPLSGEEGPLGLLGVSPKPGLELSGQRRRLLTALSQPLAQALARAQLAQELEs 641
Cdd:COG4251 187 VLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELE- 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 642 ARLHGETEQLRSA------LLASVSHDLRTPLTSMRGSIDSLLALGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTR 715
Cdd:COG4251 266 EELEERTAELERSneeleqFAYVASHDLREPLRKISGFSQLLEEDYGDKLDEEGREYLERIRDAAERMQALIDDLLAYSR 345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 716 LGHGALKLArdWVSPGDIVGSALGRLRAVLAPLQVHTDVpAQLPLLYVHAALIEQALVNVLENAARFSP--AHGRLQVSA 793
Cdd:COG4251 346 VGRQELEFE--PVDLNELLEEVLEDLEPRIEERGAEIEV-GPLPTVRGDPTLLRQVFQNLISNAIKYSRpgEPPRIEIGA 422
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2184758710 794 GVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAARGDRGgQGTGLGLAICQGMVGAHGGHIRVEdGIEGRGTCISLFLP 872
Cdd:COG4251 423 EREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEY-EGTGIGLAIVKKIVERHGGRIWVE-SEPGEGATFYFTLP 499
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
644-873 |
4.59e-33 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 135.65 E-value: 4.59e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 644 LHGETEQL-----RSALLASVSHDLRTPLTSMRGSIDsllALGE-AIplEDrREL----LEGTRDEAERLDRYIQNLLDM 713
Cdd:NF033092 359 LHDVTEQEkieqeRREFVANVSHELRTPLTTMRSYLE---ALADgAW--KD-PELaprfLGVTQNETERMIRLVNDLLQL 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 714 TRLGHGALKLARDWVSPGDIVGSALGRLRAVLAP--LQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQV 791
Cdd:NF033092 433 SRMDSKDYKLNKEWVNFNEFFNYIIDRFEMILKNknITFKREFPKRDLWVEIDTDKITQVLDNIISNAIKYSPEGGTITF 512
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 792 SAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYtaaRGD----RGGQGTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCI 867
Cdd:NF033092 513 RLLETHNRIIISISDQGLGIPKKDLDKIFDRFY---RVDkarsRKMGGTGLGLAIAKEVVEAHGGRIWAES-EEGKGTTI 588
|
....*.
gi 2184758710 868 SLFLPL 873
Cdd:NF033092 589 YFTLPY 594
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
638-882 |
5.90e-33 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 133.95 E-value: 5.90e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 638 ELESARLHGETEQLRSALLASVSHDLRTPLTSMRGSIDsLLALGEaipLEDRRELLEGTRDEAERLDRYIQNLLDMTRlg 717
Cdd:COG5809 256 KLEELLRKSEKLSVVGELAAGIAHEIRNPLTSLKGFIQ-LLKDTI---DEEQKTYLDIMLSELDRIESIISEFLVLAK-- 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 718 HGALKLARdwVSPGDIVGS--ALGRLRAVLAPLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGV 795
Cdd:COG5809 330 PQAIKYEP--KDLNTLIEEviPLLQPQALLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNITIETKA 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 796 VDE-QLFFAVADEGPGIPEDERAKIFDMFYTaargdRGGQGTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCISLFLPLP 874
Cdd:COG5809 408 EDDdKVVISVTDEGCGIPEERLKKLGEPFYT-----TKEKGTGLGLMVSYKIIEEHGGKITVES-EVGKGTTFSITLPIK 481
|
....*...
gi 2184758710 875 TQPGPERE 882
Cdd:COG5809 482 LSEQVSMN 489
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
767-874 |
2.80e-32 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 121.22 E-value: 2.80e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 767 LIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAARGDRGGQGTGLGLAICQGM 846
Cdd:smart00387 5 RLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIGGTGLGLSIVKKL 84
|
90 100
....*....|....*....|....*...
gi 2184758710 847 VGAHGGHIRVEDGiEGRGTCISLFLPLP 874
Cdd:smart00387 85 VELHGGEISVESE-PGGGTTFTITLPLE 111
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
661-874 |
2.81e-32 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 131.51 E-value: 2.81e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 661 HDLRTPLTSMRGSIDsLLAlgEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRL-GHGALkLARDWVSPGDIVGSALG 739
Cdd:PRK11100 265 HELKSPLAAIRGAAE-LLQ--EDPPPEDRARFTGNILTQSARLQQLIDRLLELARLeQRQEL-EVLEPVALAALLEELVE 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 740 RL--RAVLAPLQVHTDVPAqlplLYVH--AALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDE 815
Cdd:PRK11100 341 AReaQAAAKGITLRLRPDD----ARVLgdPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPDYA 416
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2184758710 816 RAKIFDMFYTAARGDRGGQGTGLGLAICQGMVGAHGGHIRVEDGIEGrGTCISLFLPLP 874
Cdd:PRK11100 417 LPRIFERFYSLPRPANGRKSTGLGLAFVREVARLHGGEVTLRNRPEG-GVLATLTLPRH 474
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
768-871 |
7.78e-32 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 119.63 E-value: 7.78e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAaRGDRGGQGTGLGLAICQGMV 847
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRG-DKSREGGGTGLGLAIVRRIV 79
|
90 100
....*....|....*....|....
gi 2184758710 848 GAHGGHIRVEDgIEGRGTCISLFL 871
Cdd:cd00075 80 EAHGGRITVES-EPGGGTTFTVTL 102
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
655-873 |
2.62e-31 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 130.47 E-value: 2.62e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 655 LLASVSHDLRTPLTSMRGSIDSLLALGEAIPledRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALklarDWVSPGDIV 734
Cdd:PRK11360 393 LVAGVAHEIRNPLTAIRGYVQIWRQQTSDPP---SQEYLSVVLREVDRLNKVIDQLLEFSRPRESQW----QPVSLNALV 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 735 GSALGRLRAVL--APLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVV-DEQLFFAVADEGPGI 811
Cdd:PRK11360 466 EEVLQLFQTAGvqARVDFETELDNELPPIWADPELLKQVLLNILINAVQAISARGKIRIRTWQYsDGQVAVSIEDNGCGI 545
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2184758710 812 PEDERAKIFDMFYTAArgdrgGQGTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCISLFLPL 873
Cdd:PRK11360 546 DPELLKKIFDPFFTTK-----AKGTGLGLALSQRIINAHGGDIEVES-EPGVGTTFTLYLPI 601
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
643-872 |
3.88e-31 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 126.22 E-value: 3.88e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 643 RLHGETEQLRSAL------LASVSHDLRTPLTSMRGSIDSLlALG-----EAIPLEDRRELLEGTRDEAERLDRYIQNLL 711
Cdd:PRK09303 136 VLRQENETLLEQLkfkdrvLAMLAHDLRTPLTAASLALETL-ELGqidedTELKPALIEQLQDQARRQLEEIERLITDLL 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 712 DMTRLGHGALKLARDWVSPGDIVGSALGRLRAVLA--PLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRL 789
Cdd:PRK09303 215 EVGRTRWEALRFNPQKLDLGSLCQEVILELEKRWLakSLEIQTDIPSDLPSVYADQERIRQVLLNLLDNAIKYTPEGGTI 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 790 QVSA-GVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAARgDRGGQGTGLGLAICQGMVGAHGGHIRVeDGIEGRGTCIS 868
Cdd:PRK09303 295 TLSMlHRTTQKVQVSICDTGPGIPEEEQERIFEDRVRLPR-DEGTEGYGIGLSVCRRIVRVHYGQIWV-DSEPGQGSCFH 372
|
....
gi 2184758710 869 LFLP 872
Cdd:PRK09303 373 FTLP 376
|
|
| USP_KdpD-like |
cd01987 |
USP domain of the osmosensitive K+ channel histidine kinase family; The KdpDE two component ... |
248-365 |
6.67e-31 |
|
USP domain of the osmosensitive K+ channel histidine kinase family; The KdpDE two component system is widespread in bacteria and archaea; it controls potassium homeostasis and virulence by regulating the transcription of multiple genes, including a kdpFABC operon, which encodes a high-affinity P-type ATPase transporter. The KdpD histidine kinase (HK, EC:2.7.13.3) contain an N-terminal sensory cytoplasmic region (NTR) composed of KdpD' and universal stress protein (USP) domains, a canonical transmembrane domain, and a cytoplasmic C-terminal region with a transmitter GAF domain and an EnvZ-like catalytic HK domain. Proteins containing the USP domain are induced by many environmental stressors such as nutrient starvation, drought, extreme temperatures, high salinity, and the presence of uncouplers, antibiotics, and metals. It enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity.
Pssm-ID: 467491 [Multi-domain] Cd Length: 124 Bit Score: 117.73 E-value: 6.67e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 248 RLLVGVDGDAQAERLVRHASRVAQRRHLPWSLVHIDNGRAR--DEQSRLRLQNAQQLAERLGGEVVLLRAGEVAKTLIQH 325
Cdd:cd01987 1 RILVCISSSPTSEKLIRRAARLAERLNGELTAVYVETPEESrlDEESQRRLLTNLKLAEELGAEVVSVEGDDVAEAIVEF 80
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2184758710 326 AAERRASLVLVGQSRMRWRRRLFGGGLAARLLRNARGLEI 365
Cdd:cd01987 81 ARERNVTQIVLGQSRRRRWRRLFKGSLVDRLLREAPNIDV 120
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
649-875 |
7.33e-29 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 120.79 E-value: 7.33e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 649 EQLRSALLASVSHDLRTPLTSMRgsidslLAlGEAIPLEDRReLLEGTRDEAERLDRYIQNLLDMTRLGHgalKLARDWV 728
Cdd:PRK09467 226 EDDRTLLMAGVSHDLRTPLTRIR------LA-TEMMSEEDGY-LAESINKDIEECNAIIEQFIDYLRTGQ---EMPMEMA 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 729 S----PGDIVGSALGRLRavlaplQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSpaHGRLQVSAGVVDEQLFFAV 804
Cdd:PRK09467 295 DlnalLGEVIAAESGYER------EIETALQPGPIEVPMNPIAIKRALANLVVNAARYG--NGWIKVSSGTEGKRAWFQV 366
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2184758710 805 ADEGPGIPEDERAKIFDMFytaARGD--RGGQGTGLGLAICQGMVGAHGGHIRVEDGIEGrGTCISLFLPLPT 875
Cdd:PRK09467 367 EDDGPGIPPEQLKHLFQPF---TRGDsaRGSSGTGLGLAIVKRIVDQHNGKVELGNSEEG-GLSARAWLPLTT 435
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
638-873 |
2.34e-28 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 122.83 E-value: 2.34e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 638 ELESARLHGETEQLR-SALLASVSHDLRTPLTSMRGSIdSLLALGEAIPleDRRELLEGTRDEAERLDRYIQNLLDMTRL 716
Cdd:PRK15347 383 ALAEAKQRAEQANKRkSEHLTTISHEIRTPLNGVLGAL-ELLQNTPLTA--EQMDLADTARQCTLSLLAIINNLLDFSRI 459
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 717 GHGALKLARDWVSPGDIVGSALG--RLRAVLAPLQVHTDVPAQLPL-LYVHAALIEQALVNVLENAARFSPaHGRLQVSA 793
Cdd:PRK15347 460 ESGQMTLSLEETALLPLLDQAMLtiQGPAQSKSLTLRTFVGAHVPLyLHLDSLRLRQILVNLLGNAVKFTE-TGGIRLRV 538
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 794 GVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAargDRGGQGTGLGLAICQGMVGAHGGHIRVeDGIEGRGTCISLFLPL 873
Cdd:PRK15347 539 KRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQA---DTHSQGTGLGLTIASSLAKMMGGELTL-FSTPGVGSCFSLVLPL 614
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
648-868 |
7.22e-28 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 115.38 E-value: 7.22e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 648 TEQLRSALLASVSHDLRTPLTSMRGSIDSLLALGEAIPlEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLARDW 727
Cdd:TIGR02966 110 LEQMRRDFVANVSHELRTPLTVLRGYLETLADGPDEDP-EEWNRALEIMLEQSQRMQSLVEDLLTLSRLESAASPLEDEP 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 728 VSpgdiVGSALGRLRAVLAPL------QVHTDVPAQLPLLYVHAALiEQALVNVLENAARFSPAHGRLQVSAGVVDEQLF 801
Cdd:TIGR02966 189 VD----MPALLDHLRDEAEALsqgknhQITFEIDGGVDVLGDEDEL-RSAFSNLVSNAIKYTPEGGTITVRWRRDGGGAE 263
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2184758710 802 FAVADEGPGIPEDERAKIFDMFYtaaRGDRGGQ----GTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCIS 868
Cdd:TIGR02966 264 FSVTDTGIGIAPEHLPRLTERFY---RVDKSRSrdtgGTGLGLAIVKHVLSRHHARLEIES-ELGKGSTFS 330
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
768-875 |
1.19e-25 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 102.06 E-value: 1.19e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFSPAHGRLQVSAgVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAARgdRGGQGTGLGLAICQGMV 847
Cdd:pfam02518 6 LRQVLSNLLDNALKHAAKAGEITVTL-SEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADK--RGGGGTGLGLSIVRKLV 82
|
90 100
....*....|....*....|....*...
gi 2184758710 848 GAHGGHIRVEDGiEGRGTCISLFLPLPT 875
Cdd:pfam02518 83 ELLGGTITVESE-PGGGTTVTLTLPLAQ 109
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
642-857 |
2.44e-25 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 110.17 E-value: 2.44e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 642 ARLHGETEQLrSALLASVSHDLRTPLTSMRGSIDslLALGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGAL 721
Cdd:TIGR01386 232 GRLEDAFQRL-SQFSADLAHELRTPLTNLLGQTQ--VALSQPRTGEEYREVLESNLEELERLSRMVSDMLFLARADNGQL 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 722 KLARDWVSpgdiVGSALGRLRAVLAPLQVHTDVPAQLP---LLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVVDE 798
Cdd:TIGR01386 309 ALERVRLD----LAAELAKVAEYFEPLAEERGVRIRVEgegLVRGDPQMFRRAISNLLSNALRHTPDGGTITVRIERRSD 384
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 799 QLFFAVADEGPGIPEDERAKIFDMFYTAARGDRG-GQGTGLGLAICQGMVGAHGGHIRVE 857
Cdd:TIGR01386 385 EVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSNsGEGTGLGLAIVRSIMEAHGGRASAE 444
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
649-880 |
3.75e-25 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 109.72 E-value: 3.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 649 EQLRSALLASVSHDLRTPLTSMRGSIdsllalgEAIPLEDRR---ELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLAR 725
Cdd:PRK10549 237 EQMRRDFMADISHELRTPLAVLRGEL-------EAIQDGVRKftpESVASLQAEVGTLTKLVDDLHQLSLSDEGALAYRK 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 726 DWVSPGDIVGSALGRLRAVLA--PLQVHTDVPAQLPLLYVHAALIeQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFA 803
Cdd:PRK10549 310 TPVDLVPLLEVAGGAFRERFAsrGLTLQLSLPDSATVFGDPDRLM-QLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLT 388
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2184758710 804 VADEGPGIPEDERAKIFDMFYTA-ARGDRGGQGTGLGLAICQGMVGAHGGHIRVEDGIEGrGTCISLFLPLPTQPGPE 880
Cdd:PRK10549 389 FADSAPGVSDEQLQKLFERFYRTeGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFG-GVSITVELPLERDLQRE 465
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
655-873 |
5.44e-24 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 106.41 E-value: 5.44e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 655 LLASVSHDLRTPLTSMRGsidslLA--LGEAIPLE-DRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLardwVSPG 731
Cdd:PRK10364 240 LAAGVAHEIRNPLSSIKG-----LAkyFAERAPAGgEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQA----VDLN 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 732 DIVGSALGRLR--AVLAPLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGP 809
Cdd:PRK10364 311 DLINHSLQLVSqdANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGK 390
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2184758710 810 GIPEDERAKIFDMFYTAArgdrgGQGTGLGLAICQGMVGAHGGHIRVeDGIEGRGTCISLFLPL 873
Cdd:PRK10364 391 GIAADQLEAIFTPYFTTK-----AEGTGLGLAVVHNIVEQHGGTIQV-ASQEGKGATFTLWLPV 448
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
649-873 |
4.84e-22 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 100.39 E-value: 4.84e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 649 EQLRSA---LLASVSHDLRTPLTSMRgsidslLALGEAipledRRELLEG---TR--DEAERLDRYIQNLLDMTRLGHG- 719
Cdd:PRK09470 237 ERMMTSqqrLLSDISHELRTPLTRLQ------LATALL-----RRRQGESkelERieTEAQRLDSMINDLLVLSRNQQKn 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 720 -----ALKLARDWvspGDIVGSA------LGRLRAVLAPlqvhtdvPAQLPLlYVHAALIEQALVNVLENAARFSpaHGR 788
Cdd:PRK09470 306 hlereTFKANSLW---SEVLEDAkfeaeqMGKSLTVSAP-------PGPWPI-NGNPNALASALENIVRNALRYS--HTK 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 789 LQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFY--TAARgDRGGQGTGLGLAICQGMVGAHGGHIRVEDGIEGrGTC 866
Cdd:PRK09470 373 IEVAFSVDKDGLTITVDDDGPGVPEEEREQIFRPFYrvDEAR-DRESGGTGLGLAIVENAIQQHRGWVKAEDSPLG-GLR 450
|
....*..
gi 2184758710 867 ISLFLPL 873
Cdd:PRK09470 451 LTIWLPL 457
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
766-873 |
5.87e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 91.33 E-value: 5.87e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 766 ALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAargDRGGQGTGLGLAICQG 845
Cdd:cd16943 2 SQLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTT---KPVGEGTGLGLSLSYR 78
|
90 100
....*....|....*....|....*...
gi 2184758710 846 MVGAHGGHIRVEDgIEGRGTCISLFLPL 873
Cdd:cd16943 79 IIQKHGGTIRVAS-VPGGGTRFTIILPI 105
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-873 |
1.81e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 90.08 E-value: 1.81e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFSPahGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTA--ARgDRGGQGTGLGLAICQG 845
Cdd:cd16949 1 LARALENVLRNALRYSP--SKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVdsAR-DRESGGTGLGLAIAER 77
|
90 100
....*....|....*....|....*...
gi 2184758710 846 MVGAHGGHIRVEDGiEGRGTCISLFLPL 873
Cdd:cd16949 78 AIEQHGGKIKASNR-KPGGLRVRIWLPA 104
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
654-876 |
2.06e-21 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 98.14 E-value: 2.06e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 654 ALLAS-------VSHDLRTPLTSMRGSIDSLLALGEAIPLEDRRELlegtrdeaERLDRYIQNLLDMTRLGHGALKLARD 726
Cdd:PRK10604 207 ALIASkkqlidgIAHELRTPLVRLRYRLEMSDNLSAAESQALNRDI--------GQLEALIEELLTYARLDRPQNELHLS 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 727 WVSPGDIVGSALGRLRAVLAPLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFspAHGRLQVSAGVVDEQLFFAVAD 806
Cdd:PRK10604 279 EPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRY--AHSRVRVSLLLDGNQACLIVED 356
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2184758710 807 EGPGIPEDERAKIFDMF--YTAARgDRGGQGTGLGLAICQGMVGAHGGHIRVEDGIEGrGTCISLFLPLPTQ 876
Cdd:PRK10604 357 DGPGIPPEERERVFEPFvrLDPSR-DRATGGCGLGLAIVHSIALAMGGSVNCDESELG-GARFSFSWPVWHN 426
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
657-879 |
4.58e-21 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 95.81 E-value: 4.58e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 657 ASVSHDLRTPLTSMRGSIDSLLALG--EAIPLEDRRELLEGTrdeaerldryIQNLLDMTRLGH---GALKLARDWVSpg 731
Cdd:PRK10755 142 ADVAHELRTPLAGIRLHLELLEKQHhiDVAPLIARLDQMMHT----------VEQLLQLARAGQsfsSGHYQTVKLLE-- 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 732 DIVGSALGRLRAVLAPLQVHTDVPAQLPLLYVH--AALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGP 809
Cdd:PRK10755 210 DVILPSQDELSEMLEQRQQTLLLPESAADITVQgdATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGGAVLAVEDEGP 289
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 810 GIPEDERAKIFDMFYtaaRGDRGGQGTGLGLAICQGMVGAHGGHIRVEDGIEGRGTCISLFLPLPTQPGP 879
Cdd:PRK10755 290 GIDESKCGELSKAFV---RMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQERSGTRAWVWLPKAQNVAN 356
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
638-880 |
4.74e-21 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 99.21 E-value: 4.74e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 638 ELESARLHGE-TEQLRSALLASVSHDLRTPLTSMRGSIdSLLALGEAIPleDRRELLEGTRDEAERLDRYIQNLLDMTRL 716
Cdd:PRK11466 429 EHRQARAEAEkASQAKSAFLAAMSHEIRTPLYGILGTA-QLLADNPALN--AQRDDLRAITDSGESLLTILNDILDYSAI 505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 717 --GHGALKLARDWVSPGDIVGSAL----GRLRAvlAPLQVHTDVPAQLP-LLYVHAALIEQALVNVLENAARFSPaHGRL 789
Cdd:PRK11466 506 eaGGKNVSVSDEPFEPRPLLESTLqlmsGRVKG--RPIRLATDIADDLPtALMGDPRRIRQVITNLLSNALRFTD-EGSI 582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 790 QVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAArGDRGgqGTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCISL 869
Cdd:PRK11466 583 VLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVS-GKRG--GTGLGLTISSRLAQAMGGELSATS-TPEVGSCFCL 658
|
250
....*....|...
gi 2184758710 870 FLPL--PTQPGPE 880
Cdd:PRK11466 659 RLPLrvATAPVPK 671
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
768-873 |
2.46e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 86.78 E-value: 2.46e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFSPaHGRLQVSAGVVDE-----QLFFAVADEGPGIPEDERAKIFDMFYTAARGD-RGGQGTGLGLA 841
Cdd:cd16922 1 LRQILLNLLGNAIKFTE-EGEVTLRVSLEEEeedgvQLRFSVEDTGIGIPEEQQARLFEPFSQADSSTtRKYGGTGLGLA 79
|
90 100 110
....*....|....*....|....*....|..
gi 2184758710 842 ICQGMVGAHGGHIRVEDgIEGRGTCISLFLPL 873
Cdd:cd16922 80 ISKKLVELMGGDISVES-EPGQGSTFTFTLPL 110
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
655-874 |
9.38e-20 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 93.64 E-value: 9.38e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 655 LLASVSHDLRTPLTSMRGSIdSLLALGeaipLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLardwVSPGDIV 734
Cdd:COG5805 290 LAAGIAHEIRNPLTSIKGFL-QLLQPG----IEDKEEYFDIMLSELDRIESIISEFLALAKPQAVNKEK----ENINELI 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 735 GS--ALGRLRAVLAPLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIP 812
Cdd:COG5805 361 QDvvTLLETEAILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIP 440
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2184758710 813 EDERAKIFDMFYTAARgdrggQGTGLGLAICQGMVGAHGGHIRVEDGiEGRGTCISLFLPLP 874
Cdd:COG5805 441 EERLKKLGEPFFTTKE-----KGTGLGLMVSYKIIENHNGTIDIDSK-VGKGTTFTITLPLS 496
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
765-862 |
5.20e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 82.89 E-value: 5.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 765 AALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAARGDRGGQGTGLGLAICQ 844
Cdd:cd16945 2 PFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGQKSTGLGLAFVQ 81
|
90
....*....|....*...
gi 2184758710 845 GMVGAHGGHIRVEDGIEG 862
Cdd:cd16945 82 EVAQLHGGRITLRNRPDG 99
|
|
| DUF4118 |
pfam13493 |
Domain of unknown function (DUF4118); This domain is found in a wide variety of bacterial ... |
411-494 |
5.77e-18 |
|
Domain of unknown function (DUF4118); This domain is found in a wide variety of bacterial signalling proteins. It is likely to be a transmembrane domain involved in ligand sensing.
Pssm-ID: 463897 Cd Length: 107 Bit Score: 80.20 E-value: 5.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 411 LPLPNISLVFLAAVLLVGVRSSLGPSLVCAALSFLTYDFLFIPPNFSFSIQREEDVLTLLFFLLMAALTGNLAARQRRQL 490
Cdd:pfam13493 22 LPLANIALLFLLAVLLVALRGGRGPGLLAAVLSVLLFNYFFTPPYFTFTVSDPGYLLTLVVFLLVALLTSTLTARLRRQA 101
|
....
gi 2184758710 491 QALR 494
Cdd:pfam13493 102 RQAR 105
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-857 |
1.00e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 79.43 E-value: 1.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYtaaRGD----RGGQGTGLGLAIC 843
Cdd:cd16946 5 LQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFY---RVEssrnRASGGSGLGLAIC 81
|
90
....*....|....
gi 2184758710 844 QGMVGAHGGHIRVE 857
Cdd:cd16946 82 HNIALAHGGTISAE 95
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
659-872 |
4.01e-17 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 85.46 E-value: 4.01e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 659 VSHDLRTPLTSMRGSIDSLLALGEAIPLEDRR--ELLegtRDEAERLDRYIQNLLDMTRLGHGALKLARDWVSPGDIVGS 736
Cdd:NF040691 278 VSHELRTPLTTIRMAADVIHDSRDDFDPATARsaELL---HTELDRFESLLSDLLEISRFDAGAAELDVEPVDLRPLVRR 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 737 ALGRLR--AVLAPLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSpAHGRLQVSAGVVDEQLFFAVADEGPGIPED 814
Cdd:NF040691 355 VVDALRqlAERAGVELRVDAPGTPVVAEVDPRRVERVLRNLVVNAIEHG-EGKPVVVTVAQDDTAVAVTVRDHGVGLKPG 433
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 815 ERAKIFDMFYTA--ARGDRGGqGTGLGLAICQGMVGAHGGHIRVEdGIEGRGTCISLFLP 872
Cdd:NF040691 434 EVALVFDRFWRAdpARARTTG-GTGLGLAIALEDARLHGGWLEAW-GRPGQGSQFRLTLP 491
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-872 |
4.90e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 77.37 E-value: 4.90e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFS--PAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAaRGDRGGQGTGLGLAICQG 845
Cdd:cd16921 1 LGQVLTNLLGNAIKFRrpRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRL-HSREEYEGTGVGLAIVRK 79
|
90 100
....*....|....*....|....*..
gi 2184758710 846 MVGAHGGHIRVEDGiEGRGTCISLFLP 872
Cdd:cd16921 80 IIERHGGRIWLESE-PGEGTTFYFTLP 105
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
767-871 |
5.53e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 77.45 E-value: 5.53e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 767 LIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFfAVADEGPGIPEDERAKIFDMFYtaaRGD-RGGQGTGLGLAICQG 845
Cdd:cd16940 13 LLFLLLRNLVDNAVRYSPQGSRVEIKLSADDGAVI-RVEDNGPGIDEEELEALFERFY---RSDgQNYGGSGLGLSIVKR 88
|
90 100
....*....|....*....|....*.
gi 2184758710 846 MVGAHGGHIRVEDGiEGRGTCISLFL 871
Cdd:cd16940 89 IVELHGGQIFLGNA-QGGGLEAWVRL 113
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-872 |
7.65e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 76.72 E-value: 7.65e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFspAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYtaaRGD--RGGQGTGLGLAICQG 845
Cdd:cd16950 1 LKRVLSNLVDNALRY--GGGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFY---RGDnaRGTSGTGLGLAIVQR 75
|
90 100
....*....|....*....|....*..
gi 2184758710 846 MVGAHGGHIRVEDGiEGRGTCISLFLP 872
Cdd:cd16950 76 ISDAHGGSLTLANR-AGGGLCARIELP 101
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
641-873 |
1.12e-16 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 82.97 E-value: 1.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 641 SARLHGETEQLRSAL---------LASVSHDLRTPLTSMRGsidsLLALGEaipLEDRRELLEGTRDEAERLDRYIQNLL 711
Cdd:COG3290 169 TFRDRTELERLEEELegvkelaeaLRAQRHDFRNHLHTISG----LLQLGE---YDEALEYIDEISEELQELIDSLLSRI 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 712 DMTRLG---HGALKLARDwvspgdivgsaLGrlravlapLQVHTDVPAQLPLLYVHAALIEQALVNVLENA----ARFSP 784
Cdd:COG3290 242 GNPVLAallLGKAARARE-----------RG--------IDLTIDIDSDLPDLPLSDTDLVTILGNLLDNAieavEKLPE 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 785 AHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDM-FYTaargdRGGQGTGLGLAICQGMVGAHGGHIRVEDGiEGR 863
Cdd:COG3290 303 EERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERgFST-----KLGEGRGLGLALVKQIVEKYGGTIEVESE-EGE 376
|
250
....*....|
gi 2184758710 864 GTCISLFLPL 873
Cdd:COG3290 377 GTVFTVRLPK 386
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
657-874 |
1.76e-16 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 84.22 E-value: 1.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 657 ASVSHDLRTPLTSMRGSIDSLLAlgeaIPLEDR-RELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLARdwvSPGDIVG 735
Cdd:PRK11091 288 STISHELRTPLNGIVGLSRILLD----TELTAEqRKYLKTIHVSAITLGNIFNDIIDMDKMERRKLQLDN---QPIDFTD 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 736 -----SALGRLRAVLAPLQVHTDVPAQLPllyvHAALIE-----QALVNVLENAARFSPAHGrlqVSAGVVDEQ---LFF 802
Cdd:PRK11091 361 fladlENLSGLQAEQKGLRFDLEPLLPLP----HKVITDgtrlrQILWNLISNAVKFTQQGG---VTVRVRYEEgdmLTF 433
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2184758710 803 AVADEGPGIPEDERAKIFDMFYTAARGdRGGQ---GTGLGLAICQGMVGAHGGHIRVeDGIEGRGTCISLFLPLP 874
Cdd:PRK11091 434 EVEDSGIGIPEDELDKIFAMYYQVKDS-HGGKpatGTGIGLAVSKRLAQAMGGDITV-TSEEGKGSCFTLTIHAP 506
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-873 |
1.82e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 75.54 E-value: 1.82e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFspAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAARG-DRGGQGTGLGLAICQGM 846
Cdd:cd16939 1 MARALDNLLRNALRY--AHRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSrDRATGGFGLGLAIVHRV 78
|
90 100
....*....|....*....|....*..
gi 2184758710 847 VGAHGGHIRVEDGIEGrGTCISLFLPL 873
Cdd:cd16939 79 ALWHGGHVECDDSELG-GACFRLTWPR 104
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
652-873 |
1.35e-15 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 81.70 E-value: 1.35e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 652 RSALLASVSHDLRTPLTSMRGSIDslLALGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLARDWVSPG 731
Cdd:PRK09959 712 KSQFLATMSHEIRTPISSIMGFLE--LLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIP 789
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 732 DIVGSALGRLRAVLAPLQVHTDVPAQLP---LLYVHAALIEQALVNVLENAARFSpAHGRLQVSAGVV--DEQ---LFFA 803
Cdd:PRK09959 790 TLVQNTCHSFGAIAASKSIALSCSSTFPdhyLVKIDPQAFKQVLSNLLSNALKFT-TEGAVKITTSLGhiDDNhavIKMT 868
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 804 VADEGPGIPEDERAKIFDMFYTAARGdRGGQGTGLGLAICQGMVGAHGGHIRVEDGiEGRGTCISLFLPL 873
Cdd:PRK09959 869 IMDSGSGLSQEEQQQLFKRYSQTSAG-RQQTGSGLGLMICKELIKNMQGDLSLESH-PGIGTTFTITIPV 936
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
770-872 |
2.90e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 72.61 E-value: 2.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 770 QALVNVLENAARFSP-AHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTA-ARGDRGGQGTGLGLAICQGMV 847
Cdd:cd16953 3 QVLRNLIGNAISFSPpDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTErPANEAFGQHSGLGLSISRQII 82
|
90 100
....*....|....*....|....*...
gi 2184758710 848 GAHGGHIRVE---DGIEGRGTCISLFLP 872
Cdd:cd16953 83 EAHGGISVAEnhnQPGQVIGARFTVQLP 110
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-871 |
3.15e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 72.10 E-value: 3.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENA--ARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAargDRGGQGTGLGLAICQG 845
Cdd:cd16976 1 IQQVLMNLLQNAldAMGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTT---KPVGKGTGLGLSISYG 77
|
90 100
....*....|....*....|....*.
gi 2184758710 846 MVGAHGGHIRVEDGiEGRGTCISLFL 871
Cdd:cd16976 78 IVEEHGGRLSVANE-EGAGARFTFDL 102
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
748-862 |
7.09e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 72.28 E-value: 7.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 748 LQVHTDVPAQLPLLYVHAALIEqALVNVLENAARFspAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDmfyTAA 827
Cdd:cd16954 19 VSISLDISPELRFPGERNDLME-LLGNLLDNACKW--CLEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQ---RGQ 92
|
90 100 110
....*....|....*....|....*....|....*
gi 2184758710 828 RGDRGGQGTGLGLAICQGMVGAHGGHIRVEDGIEG 862
Cdd:cd16954 93 RLDEQRPGQGLGLAIAKEIVEQYGGELSLSDSPLG 127
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
650-873 |
7.31e-15 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 79.25 E-value: 7.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 650 QLRSALLASVSHDLRTPLTSMRGSIDSLLAlgEAIPLEDRReLLEGTRDEAERLDRYIQNLLDMTRLGHGALKLARDWVS 729
Cdd:PRK10841 445 QSKSMFLATVSHELRTPLYGIIGNLDLLQT--KELPKGVDR-LVTAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFS 521
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 730 PGD----IVGSALgrlravlaPLQV----------HTDVPAQL---PLLyvhaalIEQALVNVLENAARFSpAHGRLQVS 792
Cdd:PRK10841 522 PREvinhITANYL--------PLVVkkrlglycfiEPDVPVALngdPMR------LQQVISNLLSNAIKFT-DTGCIVLH 586
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 793 AGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAARG-DRGGQGTGLGLAICQGMVGAHGGHIRVEDGiEGRGTCISLFL 871
Cdd:PRK10841 587 VRVDGDYLSFRVRDTGVGIPAKEVVRLFDPFFQVGTGvQRNFQGTGLGLAICEKLINMMDGDISVDSE-PGMGSQFTIRI 665
|
..
gi 2184758710 872 PL 873
Cdd:PRK10841 666 PL 667
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
769-872 |
8.74e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 71.26 E-value: 8.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 769 EQALVNVLENAARFSPAHGRLQVSAG--VVDEQ-------------LFFAVADEGPGIPEDERAKIFDMFYTAargDRGG 833
Cdd:cd16919 2 ELAILNLAVNARDAMPEGGRLTIETSnqRVDADyalnyrdlipgnyVCLEVSDTGSGMPAEVLRRAFEPFFTT---KEVG 78
|
90 100 110
....*....|....*....|....*....|....*....
gi 2184758710 834 QGTGLGLAICQGMVGAHGGHIRVEDGIeGRGTCISLFLP 872
Cdd:cd16919 79 KGTGLGLSMVYGFVKQSGGHLRIYSEP-GVGTTVRIYLP 116
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-872 |
4.07e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 68.96 E-value: 4.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLEN---AARFSPAHGR---LQVSAGVVDEqLFFAVADEGPGIPEDERAKIFDMFYTAARgdrggQGTGLGLA 841
Cdd:cd16920 1 IQQVLINLVRNgieAMSEGGCERReltIRTSPADDRA-VTISVKDTGPGIAEEVAGQLFDPFYTTKS-----EGLGMGLS 74
|
90 100 110
....*....|....*....|....*....|.
gi 2184758710 842 ICQGMVGAHGGHIRVEDGiEGRGTCISLFLP 872
Cdd:cd16920 75 ICRSIIEAHGGRLSVESP-AGGGATFQFTLP 104
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
649-715 |
7.45e-14 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 66.85 E-value: 7.45e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2184758710 649 EQLRSALLASVSHDLRTPLTSMRGSIDSLlaLGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTR 715
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELL--EEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
765-872 |
1.32e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 67.56 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 765 AALIEQALVNVLENAAR------FSPAHGRLQVSAGVvDEQLFFAVADEGPGIPEDERAKIFDMFYTAArgdrgGQGTGL 838
Cdd:cd16944 2 TTQISQVLTNILKNAAEaiegrpSDVGEVRIRVEADQ-DGRIVLIVCDNGKGFPREMRHRATEPYVTTR-----PKGTGL 75
|
90 100 110
....*....|....*....|....*....|....
gi 2184758710 839 GLAICQGMVGAHGGHIRVEDGiEGRGTCISLFLP 872
Cdd:cd16944 76 GLAIVKKIMEEHGGRISLSNR-EAGGACIRIILP 108
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
768-872 |
1.57e-13 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 67.52 E-value: 1.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFSPAHGRLQVSAGVVDEQLF-FAVADEGPGIPEDERAKIFDMFYTAarGDRGGQ---GTGLGLAIC 843
Cdd:cd16925 5 YERVVLNLLSNAFKFTPDGGRIRCILEKFRLNRFlLTVSDSGPGIPPNLREEIFERFRQG--DGSSTRahgGTGLGLSIV 82
|
90 100
....*....|....*....|....*....
gi 2184758710 844 QGMVGAHGGHIRVEDgIEGRGTCISLFLP 872
Cdd:cd16925 83 KEFVELHGGTVTVSD-APGGGALFQVELP 110
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
652-719 |
3.38e-13 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 64.93 E-value: 3.38e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2184758710 652 RSALLASVSHDLRTPLTSMRGSIDSLLalgEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHG 719
Cdd:pfam00512 2 KSEFLANLSHELRTPLTAIRGYLELLR---DEKLDEEQREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
658-872 |
3.64e-13 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 73.18 E-value: 3.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 658 SVSHDLRTPLTSMRGSIDSLLALGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLardwVSPGDIVGSA 737
Cdd:COG4192 439 SLAHELNQPLNAMSMYLFSAKKALEQENYAQLPTSLDKIEGLIERMDKIIKSLRQFSRKSDTPLQP----VDLRQVIEQA 514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 738 LGRLRAVLAPLQVHTDVPaQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDEra 817
Cdd:COG4192 515 WELVESRAKPQQITLHIP-DDLMVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRVAISDNGNGWPLVD-- 591
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2184758710 818 KIFDMFYTAARgdrggQGTGLGLAICQGMVGAHGGHIRVEDGIEgRGTCISLFLP 872
Cdd:COG4192 592 KLFTPFTTTKE-----VGLGLGLSICRSIMQQFGGDLYLASTLE-RGAMVILEFN 640
|
|
| UspA |
COG0589 |
Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms]; |
248-361 |
4.01e-13 |
|
Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];
Pssm-ID: 440354 Cd Length: 136 Bit Score: 67.25 E-value: 4.01e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 248 RLLVGVDGDAQAERLVRHASRVAQRRHLPWSLVHI------------DNGRARDEQSRLRLQNAQQLAERLGGEV-VLLR 314
Cdd:COG0589 4 RILVPTDGSEEAERALEYAAELAKALGAELHLLHVvdpppsaaagpeELEEELREEAEEALEEAAERLEEAGVEVeTVVR 83
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 2184758710 315 AGEVAKTLIQHAAERRASLVLVGQSRMRWRRRLFGGGLAARLLRNAR 361
Cdd:COG0589 84 EGDPAEAILEAAEELDADLIVMGSRGRSGLRRLLLGSVAERVLRHAP 130
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
657-872 |
6.79e-13 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 72.11 E-value: 6.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 657 ASVSHDLRTPLTSMrgSIDSLLALGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALKLARDWVSPGDIVGS 736
Cdd:PRK09835 267 ADIAHEIRTPITNL--ITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLDLADEVGK 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 737 ALGRLRAVLAPLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDER 816
Cdd:PRK09835 345 VFDFFEAWAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEHL 424
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 817 AKIFDMFYtaaRGD----RGGQGTGLGLAICQGMVGAHGGHIRVEDgiEGRGTCISLFLP 872
Cdd:PRK09835 425 PRLFDRFY---RVDpsrqRKGEGSGIGLAIVKSIVVAHKGTVAVTS--DARGTRFVISLP 479
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
652-719 |
1.58e-12 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 63.35 E-value: 1.58e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2184758710 652 RSALLASVSHDLRTPLTSMRGSIDSLLalgEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHG 719
Cdd:smart00388 2 KREFLANLSHELRTPLTAIRGYLELLL---DTELSEEQREYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
482-877 |
1.84e-12 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 71.25 E-value: 1.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 482 LAARQRRQLQALRDTQEETSELLDLSRKLTAA--TDRQAVISAAAHHLQGWSDLELC-LLNRDGQGGWKVETGAALNLTE 558
Cdd:PRK13837 258 LVLRLRARTRVLRRRAAFEEVIAAISRCFEAAspHELEASIEAALGILAKFFDADSAaLALVDVGGRARIWTFPGLTPDP 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 559 AERAAADwAWQHDQPAGMGtGTLPFGRWWWWPLSG---EEGPLGLLGVSPKPG------LELSGQRRRLLTALSQPLAQA 629
Cdd:PRK13837 338 VWPDRLR-ALASTVKAAER-DVVFVDRNGPVRKRScltRRGPALWACLAFKSGdrivalLGLGRQRYGLRPPAGELQLLE 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 630 LARAQLAQELESARLHGETEQLRSAL-----------LAS-VSHDLRTPLTSMRGSIDslLALGEAIPLEDRRELLEGTR 697
Cdd:PRK13837 416 LALDCLAHAIERRRLETERDALERRLeharrleavgtLASgIAHNFNNILGAILGYAE--MALNKLARHSRAARYIDEII 493
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 698 DEAERLDRYIQNLLDMTRLGHGALKLardwVSPGDIVGSALGRLRAVLAP---LQVHTDV--------PAQLpllyvhaa 766
Cdd:PRK13837 494 SAGARARLIIDQILAFGRKGERNTKP----FDLSELVTEIAPLLRVSLPPgveLDFDQDQepavvegnPAEL-------- 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 767 liEQALVNVLENAARFSPAHGRLQVSAGVVD---------------EQLFFAVADEGPGIPEDERAKIFDMFYTAARGdr 831
Cdd:PRK13837 562 --QQVLMNLCSNAAQAMDGAGRVDISLSRAKlrapkvlshgvlppgRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRAG-- 637
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 2184758710 832 ggqGTGLGLAICQGMVGAHGGHIRVeDGIEGRGTCISLFLPLPTQP 877
Cdd:PRK13837 638 ---GTGLGLATVHGIVSAHAGYIDV-QSTVGRGTRFDVYLPPSSKV 679
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
767-869 |
3.81e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 63.63 E-value: 3.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 767 LIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAARGDRGGQGTGLGLAICQGM 846
Cdd:cd16975 4 LLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGHYGMGLYIAKNL 83
|
90 100
....*....|....*....|...
gi 2184758710 847 VGAHGGHIRVEDGIEGrGTCISL 869
Cdd:cd16975 84 VEKHGGSLIIENSQKG-GAEVTV 105
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
774-872 |
6.61e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 62.79 E-value: 6.61e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 774 NVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYtaaRGD--RGGQGTGLGLAICQGMVGAHG 851
Cdd:cd16923 7 NLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFY---RGDnsRNTEGAGLGLSIAKAIIELHG 83
|
90 100
....*....|....*....|.
gi 2184758710 852 GHIRVEdgIEGRGTCISLFLP 872
Cdd:cd16923 84 GSASAE--YDDNHDLFKVRLP 102
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
774-872 |
7.33e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 62.69 E-value: 7.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 774 NVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAargdRGGQGTGLGLAICQGMVGAHGGH 853
Cdd:cd16915 11 NALDALAATGAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVST----KGQGERGIGLALVRQSVERLGGS 86
|
90
....*....|....*....
gi 2184758710 854 IRVEDGIEGrGTCISLFLP 872
Cdd:cd16915 87 ITVESEPGG-GTTFSIRIP 104
|
|
| Usp |
pfam00582 |
Universal stress protein family; The universal stress protein UspA is a small cytoplasmic ... |
249-360 |
1.17e-11 |
|
Universal stress protein family; The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.
Pssm-ID: 425765 [Multi-domain] Cd Length: 137 Bit Score: 63.20 E-value: 1.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 249 LLVGVDGDAQAERLVRHASRVAQRRHLPWSLVHIDNGR---------------ARDEQSRLRLQNAQQLAERLGGEVV-- 311
Cdd:pfam00582 1 ILVAVDGSEESKRALEWAAELAKARGAELILLHVIDPPpsgaasladesaeeeELELELAEAEALAAAAAAEAGGVKVev 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2184758710 312 LLRAGEVAKTLIQHAAERRASLVLVGQSRMRWRRRLFGGGLAARLLRNA 360
Cdd:pfam00582 81 VVVVGDPAEEILEVAEEEDADLIVMGSRGRSGLSRLLLGSVAEYVLRHA 129
|
|
| USP-like |
cd00293 |
universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a ... |
248-361 |
1.17e-11 |
|
universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although USP lacks ATP-binding activity.
Pssm-ID: 467483 [Multi-domain] Cd Length: 135 Bit Score: 63.14 E-value: 1.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 248 RLLVGVDGDAQAERLVRHASRVAQRRHLPWSLVHIDNGRARDEQSRLR--------------LQNAQQLAERLGGEV-VL 312
Cdd:cd00293 1 KILVAVDGSEESERALEWALELAKRPGAELTLLHVVDPPPSSSLSGGLeeladelkeeaeelLEEAKKLAEEAGVEVeTI 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2184758710 313 LRAGEVAKTLIQHAAERRASLVLVGQSRMRWRRRLFGGGLAARLLRNAR 361
Cdd:cd00293 81 VVEGDPAEAILEEAKELGADLIVMGSRGRSGLKRLLLGSVSEYVLRHAP 129
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-872 |
4.36e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 60.49 E-value: 4.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAAR-FSPAHGRL--------QVSAGVVDEQLFF--AVADEGPGIPEDERAKIFDMFYTAARGdrggqGT 836
Cdd:cd16918 1 LIQVFLNLVRNAAQaLAGSGGEIilrtrtqrQVTLGHPRHRLALrvSVIDNGPGIPPDLQDTIFYPMVSGREN-----GT 75
|
90 100 110
....*....|....*....|....*....|....*.
gi 2184758710 837 GLGLAICQGMVGAHGGHIRVEDgiEGRGTCISLFLP 872
Cdd:cd16918 76 GLGLAIAQNIVSQHGGVIECDS--QPGHTVFSVSLP 109
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
749-857 |
1.48e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 59.45 E-value: 1.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 749 QVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAAR 828
Cdd:cd16947 2 QVEINIPDRPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLED 81
|
90 100 110
....*....|....*....|....*....|
gi 2184758710 829 G-DRGGQGTGLGLAICQGMVGAHGGHIRVE 857
Cdd:cd16947 82 SrNSAKQGNGLGLTITKRLAESMGGSIYVN 111
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
649-872 |
1.79e-10 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 63.88 E-value: 1.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 649 EQLRSALLASVSHDLRTPLTSMRGsidsLLALGEAIPLEDR-RELLEGT-RDEAERLDRYIQNLLdmtrlghgalklard 726
Cdd:PRK11006 201 EGARRNFFANVSHELRTPLTVLQG----YLEMMQDQPLEGAlREKALHTmREQTQRMEGLVKQLL--------------- 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 727 wvspgdivgsALGRLRAvlAP---LQVHTDVPAQLPLLYVHAALIEQ------------------------ALVNVLENA 779
Cdd:PRK11006 262 ----------TLSKIEA--APtidLNEKVDVPMMLRVLEREAQTLSQgkhtitfevdnslkvfgnedqlrsAISNLVYNA 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 780 ARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTA--ARGDRGGqGTGLGLAICQGMVGAHGGHIRVE 857
Cdd:PRK11006 330 VNHTPEGTHITVRWQRVPQGAEFSVEDNGPGIAPEHIPRLTERFYRVdkARSRQTG-GSGLGLAIVKHALSHHDSRLEIE 408
|
250
....*....|....*
gi 2184758710 858 DGIeGRGTCISLFLP 872
Cdd:PRK11006 409 SEV-GKGTRFSFVLP 422
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
655-872 |
2.14e-10 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 64.31 E-value: 2.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 655 LLASVSHDLRTPLTSMRGSIDSLLALGE--AIPLEDRRELLEGTRDEAERLDRYIQNLLDMTR---LGHGALKLARDWVS 729
Cdd:PRK13557 166 LTGGIAHDFNNLLQVMSGYLDVIQAALShpDADRGRMARSVENIRAAAERAATLTQQLLAFARkqrLEGRVLNLNGLVSG 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 730 PGDIVGSALG---RLRAVLAPLQVHTDV-PAQLpllyvhaaliEQALVNVLENAARFSPAHGRLQVSA-----GVVDEQL 800
Cdd:PRK13557 246 MGELAERTLGdavTIETDLAPDLWNCRIdPTQA----------EVALLNVLINARDAMPEGGRVTIRTrnveiEDEDLAM 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 801 F----------FAVADEGPGIPEDERAKIFDMFYTAargDRGGQGTGLGLAICQGMVGAHGGHIRVEDGiEGRGTCISLF 870
Cdd:PRK13557 316 YhglppgryvsIAVTDTGSGMPPEILARVMDPFFTT---KEEGKGTGLGLSMVYGFAKQSGGAVRIYSE-VGEGTTVRLY 391
|
..
gi 2184758710 871 LP 872
Cdd:PRK13557 392 FP 393
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
774-872 |
1.82e-08 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 58.00 E-value: 1.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 774 NVLENA--ARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAArgdrgGQGTGLGLAICQGMVGAHG 851
Cdd:PRK11086 440 NLIENAleAVGGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTK-----GSNRGVGLYLVKQSVENLG 514
|
90 100
....*....|....*....|.
gi 2184758710 852 GHIRVEDGIeGRGTCISLFLP 872
Cdd:PRK11086 515 GSIAVESEP-GVGTQFFVQIP 534
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-872 |
3.62e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 52.29 E-value: 3.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQalvnVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTAARGDRGGQGTGLGLAICQGMV 847
Cdd:cd16948 10 IGQ----IVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRNFQESTGMGLYLVKKLC 85
|
90 100
....*....|....*....|....*
gi 2184758710 848 GAHGGHIRVEDGiEGRGTCISLFLP 872
Cdd:cd16948 86 DKLGHKIDVESE-VGEGTTFTITFP 109
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
768-872 |
6.87e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 51.43 E-value: 6.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTA-ARGDRGGQGTGLGLAICQGM 846
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVdIERCRNTGGTGLGLAIVKHV 80
|
90 100
....*....|....*....|....*.
gi 2184758710 847 VGAHGGHIRVEDGIeGRGTCISLFLP 872
Cdd:cd16952 81 MSRHDARLLIASEL-GKGSRFTCLFP 105
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
698-876 |
7.86e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 55.79 E-value: 7.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 698 DEAERLDRYIQNLLDMTRLghgALKLARDWVSpgdiVGSALGRLRAVLA--------PLQVHTDVPAQLPLLYVhAALIE 769
Cdd:COG2972 270 EDPEEAEEMLEALSKLLRY---SLSKGDELVT----LEEELELIKSYLEiqklrfgdRLEVEIEIDEELLDLLI-PKLIL 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 770 QALVnvlENA----ARFSPAHGRLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDMFYTaargdrGGQGTGLGLA-ICQ 844
Cdd:COG2972 342 QPLV---ENAiehgIEPKEGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEELSS------KGEGRGIGLRnVRE 412
|
170 180 190
....*....|....*....|....*....|...
gi 2184758710 845 GMVGAHGGHIRVE-DGIEGRGTCISLFLPLPTQ 876
Cdd:COG2972 413 RLKLYYGEEYGLEiESEPGEGTTVTIRIPLEEE 445
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
649-873 |
1.02e-07 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 55.09 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 649 EQLRSA-------LLASVSHDLRTPLTSMRGSIdSLLAlgEAIPledRRELLEGTR---DEAERLDRYIQNLLDMTRLG- 717
Cdd:PRK11073 120 EQLQHAqqvaardLVRGLAHEIKNPLGGLRGAA-QLLS--KALP---DPALTEYTKviiEQADRLRNLVDRLLGPQRPGt 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 718 ------HGALKLARDWVS---PGDIVgsalgrlravlaplqVHTDVPAQLPLLYVHAALIEQALVNVLENAAR-FSPAHG 787
Cdd:PRK11073 194 hvtesiHKVAERVVQLVSlelPDNVR---------------LIRDYDPSLPELAHDPDQIEQVLLNIVRNALQaLGPEGG 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 788 ------RLQVSAGVVDEQLFFA----VADEGPGIPederAKIFD-MFYTAARGDRGgqGTGLGLAICQGMVGAHGGHIRV 856
Cdd:PRK11073 259 titlrtRTAFQLTLHGERYRLAaridIEDNGPGIP----PHLQDtLFYPMVSGREG--GTGLGLSIARNLIDQHSGKIEF 332
|
250
....*....|....*..
gi 2184758710 857 EDGiEGRgTCISLFLPL 873
Cdd:PRK11073 333 TSW-PGH-TEFSVYLPI 347
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
774-858 |
1.33e-07 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 55.02 E-value: 1.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 774 NVLENAARFSPAHgrLQVSAGVVDEQLFFAVADEGPGIPEDERAKIFDmfytaaRGDRGGQ---GTGLGLAICQGMVGAH 850
Cdd:PRK10815 385 NVLDNACKYCLEF--VEISARQTDEHLHIVVEDDGPGIPESKRELIFD------RGQRADTlrpGQGLGLSVAREITEQY 456
|
....*...
gi 2184758710 851 GGHIRVED 858
Cdd:PRK10815 457 EGKISAGD 464
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
643-883 |
1.93e-07 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 54.94 E-value: 1.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 643 RLHGETEQLRSALLASVSHDLRTPLTSMrgsIDSLLALGEAIPLEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGALK 722
Cdd:PRK10618 441 REYEKNQQARKAFLQNIGDELKQPLQSL---AQLAAQLRQTSDEEQQQPELDQLAEQSDVLVRLVDNIQLLNMLETQDWK 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 723 LARDWVSPG----DIVGSALGRLRAVLAPLQVHTDVPAQLpLLYVHAALIEQALVnVLENAARFSPAHGRLQVS---AGV 795
Cdd:PRK10618 518 PEQELFSLQdlidEVLPEVLPAIKRKGLQLLIHNHLKAEQ-LRIGDRDALRKILL-LLLNYAITTTAYGKITLEvdqDES 595
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 796 VDEQLFFAVADEGPGIPEDERAKIFDMFYTAARGDRGGQGTGLGLAICQGMVGAHGGH--IRVEDGIEGRGTcISLFLPL 873
Cdd:PRK10618 596 SPDRLTIRILDTGAGVSIKELDNLHFPFLNQTQGDRYGKASGLTFFLCNQLCRKLGGHltIKSREGLGTRYS-IHLKMLA 674
|
250
....*....|
gi 2184758710 874 PTQPGPEREP 883
Cdd:PRK10618 675 ADPEVEEEEE 684
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
661-862 |
1.56e-06 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 51.57 E-value: 1.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 661 HDLRTPLTSMRGSID-SLLALGEAiplEDRRELLEGTRDEAERLDRYIQNLLDMTRLGHGAlklardwvSPGDIVGSALG 739
Cdd:PRK10337 246 HELRSPLAALKVQTEvAQLSDDDP---QARKKALLQLHAGIDRATRLVDQLLTLSRLDSLD--------NLQDVAEIPLE 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 740 RL--RAVL--------APLQVHTDVPAQLPLLYVHAALIEQALVNVLENAARFSPAHGRLQVsagVVDEQLFfAVADEGP 809
Cdd:PRK10337 315 DLlqSAVMdiyhtaqqAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDV---TLNARNF-TVRDNGP 390
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2184758710 810 GIPEDERAKIFDMFYTAArgdrgGQ---GTGLGLAICQGMVGAHGGHIRVEDGIEG 862
Cdd:PRK10337 391 GVTPEALARIGERFYRPP-----GQeatGSGLGLSIVRRIAKLHGMNVSFGNAPEG 441
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
748-879 |
2.62e-06 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 51.39 E-value: 2.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 748 LQVHTDVPAQL---PLLyvhaalIEQALVNVLENAARFSPaHGRLQVS---AGVVDEQ--LFFAVADEGPGIPEDERAKI 819
Cdd:PRK11107 392 LNIDPDVPDNVigdPLR------LQQIITNLVGNAIKFTE-SGNIDILvelRALSNTKvqLEVQIRDTGIGISERQQSQL 464
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2184758710 820 FDMFYTA----ARgdRGGqGTGLGLAICQGMVGAHGGHIRVEDgIEGRGTCISLFLPLPTQPGP 879
Cdd:PRK11107 465 FQAFRQAdasiSR--RHG-GTGLGLVITQKLVNEMGGDISFHS-QPNRGSTFWFHLPLDLNPNP 524
|
|
| USP_Rv2623_repeat1 |
cd23944 |
universal stress protein Rv2623 and similar proteins, USP repeat 1; Mycobacterium tuberculosis ... |
249-362 |
4.54e-06 |
|
universal stress protein Rv2623 and similar proteins, USP repeat 1; Mycobacterium tuberculosis universal stress protein Rv2623 regulates mycobacterial growth in vitro and in vivo and is required for the entry of the tubercle bacillus into the chronic phase of infection in the host. In addition Rv2623 binds ATP and the growth-regulatory attribute of this USP is dependent on its ATP-binding activity. Rv2623 is thought to function as an ATP-dependent signaling intermediate in a pathway that promotes persistent infection. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although Usp lacks ATP-binding activity.
Pssm-ID: 467509 Cd Length: 140 Bit Score: 47.01 E-value: 4.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 249 LLVGVDGDAQAERLVRHASRVAQRRHLPWSLVHI---------------DNGRARDEQSRLRLQNAQQLAERLGGEVVL- 312
Cdd:cd23944 2 IIVGVDGSPASDAAVRWAAREAQLRQIPLTLVHVvppvvvswpegprpaEVLDWQQDEARQVIEQARKVAEEASGEGPPv 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2184758710 313 -----LRAGEVAKTLIQhaAERRASLVLVGQSRM-RWRRRLFgGGLAARLLRNARG 362
Cdd:cd23944 82 kveteIVPGSPVPTLVE--ASRDATMVVVGSRGIgALAGLLL-GSVSTSLVRHAHC 134
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
774-872 |
2.84e-05 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 47.52 E-value: 2.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 774 NVLENA--ARFSPAHGRLQVSAGVVDE--QLFFAVADEGPGIPEDERAKIFDMfYTAARGDRGGQgTGLGLAICQGMVGA 849
Cdd:PRK15053 439 NLLDNAfeASLRSDEGNKIVELFLSDEgdDVVIEVADQGCGVPESLRDKIFEQ-GVSTRADEPGE-HGIGLYLIASYVTR 516
|
90 100
....*....|....*....|...
gi 2184758710 850 HGGHIRVEDGiEGRGTCISLFLP 872
Cdd:PRK15053 517 CGGVITLEDN-DPCGTLFSIFIP 538
|
|
| EntF |
COG1020 |
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites ... |
26-442 |
1.44e-04 |
|
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440643 [Multi-domain] Cd Length: 1329 Bit Score: 45.62 E-value: 1.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 26 LGAAPGVGKTYAMlqaAHTQLRQGVRLIAGVVETHGRAETEALLSGLPQQPLLRSEYRGVMLEEMDLDGLLAAKPKLVLV 105
Cdd:COG1020 892 LLQHPGVREAVVV---AREDAPGDKRLVAYVVPEAGAAAAAALLRLALALLLPPYMVPAAVVLLLPLPLTGNGKLDRLAL 968
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 106 DELAHSNAPGSRHEKRWQDIQELLAAGINVFTTVNVQHLESLNDQVRGITGVHVRETLPDWVLQEADELLLIDLPSRELL 185
Cdd:COG1020 969 PAPAAAAAAAAAAPPAEEEEEEAALALLLLLVVVVGDDDFFFFGGGLGLLLLLALARAARLLLLLLLLLLLFLAAAAAAA 1048
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 186 ERLRDGKVYVPEQARAAIDAFFTQTNLMALRELAMQTAAAHVDDD--LAQGYRQLGQAAPAVRGRLLVGVDGDAQAERLV 263
Cdd:COG1020 1049 AAAAAAAAAAAAAPLAAAAAPLPLPPLLLSLLALLLALLLLLALLalLALLLLLLLLLLLLALLLLLALLLALLAALRAR 1128
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 264 RHASRVAQRRHLPWSLVHIDNGRARDEQSRLRLQNAQQLAERLGGEVVLLRAGEVAKTLIQHAAERRASLVLVGQSRMRW 343
Cdd:COG1020 1129 RAVRQEGPRLRLLVALAAALALAALLALLLAAAAAAAELLAAAALLLLLALLLLALLLLLLLLLLLLLLLLLLLLLLLLL 1208
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 344 RRRLFGGGLAARLLRNARGLEINVLDSDDMPAPPRLPDVRGLVWFDYGLAVVATIVAAALAWAVASVLPLPNISLVFLAA 423
Cdd:COG1020 1209 LLLLLLLLLLLLLLLLAAAAAALLALALLLALLALAALLALAALAALAAALLALALALLALALLLLALALLLPALARARA 1288
|
410
....*....|....*....
gi 2184758710 424 VLLVGVRSSLGPSLVCAAL 442
Cdd:COG1020 1289 ARTARALALLLLLALLLLL 1307
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
734-873 |
8.40e-04 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 40.28 E-value: 8.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 734 VGSALGRLRAVLAPLQVHTDVPAQLPLlyvhaALIEqALVNVLENAARFSPaHGRLQVSAGVVDEQLFFAVADEGPGIPE 813
Cdd:COG2172 11 LGLARRAVRALLRELGLDEDDADDLVL-----AVSE-AVTNAVRHAYGGDP-DGPVEVELELDPDGLEIEVRDEGPGFDP 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 814 DErakifdmfytAARGDRGGQGTGLGLAICQGMVgahgGHIRVEDgiEGRGTCISLFLPL 873
Cdd:COG2172 84 ED----------LPDPYSTLAEGGRGLFLIRRLM----DEVEYES--DPGGTTVRLVKRL 127
|
|
| HATPase_Phy-like |
cd16932 |
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana ... |
768-855 |
1.04e-03 |
|
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana Phytochrome A, B, C, D and E; This family includes the histidine kinase-like ATPase (HATPase) domains of plant red/far-red photoreceptors, the phytochromes, and includes the Arabidopsis thaliana phytochrome family phyA-phyE. Following red light absorption, biologically inactive forms of phytochromes convert to active forms, which rapidly convert back to inactive forms upon far-red light irradiation. Phytochromes can be considered as having an N-terminal photosensory region to which a bilin chromophore is bound, and a C-terminal output region, which includes the HATPase domain represented here, and is involved in dimerization and presumably contributes to relaying the light signal to downstream signaling events.
Pssm-ID: 340409 [Multi-domain] Cd Length: 113 Bit Score: 39.56 E-value: 1.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNVLENAARFSPAHG----------RLQVSAGVVDEQLFFAVADEGPGIPEderAKIFDMFytaaRGDRGGQGTG 837
Cdd:cd16932 7 LQQVLADFLLNAVRFTPSPGgwveikvsptKKQIGDGVHVIHLEFRITHPGQGLPE---ELVQEMF----EENQWTTQEG 79
|
90
....*....|....*...
gi 2184758710 838 LGLAICQGMVGAHGGHIR 855
Cdd:cd16932 80 LGLSISRKLVKLMNGDVR 97
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
767-871 |
3.67e-03 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 37.25 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 767 LIEQALVNVLENAARFSPaHGRLQVSAGVVDEQLFFAVADEGPGIPEDerakifdmfyTAARGDRGGQGTGLGLAICQGM 846
Cdd:cd16936 4 AVSEAVTNAVRHAYRHDG-PGPVRLELDLDPDRLRVEVTDSGPGFDPL----------RPADPDAGLREGGRGLALIRAL 72
|
90 100
....*....|....*....|....*
gi 2184758710 847 VgahgGHIRVEDGieGRGTCISLFL 871
Cdd:cd16936 73 M----DEVGYRRT--PGGKTVWLEL 91
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
692-875 |
5.02e-03 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 39.60 E-value: 5.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 692 LLEGTRDEAERLDRYIQNLLDMTRlghGALKLARDWV----SPGDIVGSALGRLRAVLAPLQVHTDVPAQLPLLYVHAAL 767
Cdd:COG4585 79 ARRLLDADPEAAREELEEIRELAR---EALAELRRLVrglrPPALDDLGLAAALEELAERLLRAAGIRVELDVDGDPDRL 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184758710 768 IEQALVNV-------LENAARFSPAHgRLQVSAGVVDEQLFFAVADEGPGIPEDERAkifdmfytaargdrggqGTGLGL 840
Cdd:COG4585 156 PPEVELALyrivqeaLTNALKHAGAT-RVTVTLEVDDGELTLTVRDDGVGFDPEAAP-----------------GGGLGL 217
|
170 180 190
....*....|....*....|....*....|....*...
gi 2184758710 841 AicqGM---VGAHGGHIRVEDGiEGRGTCISLFLPLPT 875
Cdd:COG4585 218 R---GMrerAEALGGTLTIGSA-PGGGTRVRATLPLAA 251
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
767-815 |
5.21e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 38.17 E-value: 5.21e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2184758710 767 LIEQALVNVLENAarFSP-AHGRLQVSAGVVDEQLFFAVADEGPGIPEDE 815
Cdd:cd16951 43 VVNELLQNALKHA--FSDrEGGTITIRSVVDGDYLRITVIDDGVGLPQDE 90
|
|
| |
