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Conserved domains on  [gi|2189084632|ref|WP_237115645|]
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aspartate aminotransferase family protein [Pseudoalteromonas sp. CF6-2]

Protein Classification

pyridoxal phosphate-dependent decarboxylase family protein( domain architecture ID 10000562)

pyridoxal phosphate-dependent decarboxylase family protein is primarily involved in the biosynthesis of amino acids and amino acid-derived metabolites, but it is also found in the biosynthetic pathways of amino sugars and in the synthesis or catabolism of neurotransmitters

CATH:  3.40.640.10
EC:  4.1.1.-
Gene Ontology:  GO:0016830|GO:0030170|GO:0019752
PubMed:  8690703|7748903
SCOP:  4003328

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
GadA COG0076
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ...
 36-506 9.43e-171

Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


:

Pssm-ID: 439846 [Multi-domain]  Cd Length: 460  Bit Score: 490.11  E-value: 9.43e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632  36 DYAQLIQLGISTLSERIKEVNSPTSGVQPAQLQEEFAAiDLNTPLSDINQVLEELDHLYLKHAIYFHHQDYLAHLNCPVM 115
Cdd:COG0076     1 EFRALLHQALDLAADYLAGLDRPVFGPSPEELRAALDE-PLPEEGLPPEEALAELEDLVLPGSVDWNHPRFLAFVTGGTT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 116 LTSLLAELFSSSINTAVETWDQSAGATFIEQKVIDWTCQRIGYDEGADGVFTTGGTQSNLMALLLARELAGKLEPHSHtn 195
Cdd:COG0076    80 PAALAADLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLPEGAGGVFTSGGTEANLLALLAARDRALARRVRAE-- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 196 itsGLSSnAHRYRILCSEYSHFSIQKAAALLGLGHDAVISVACDENRCIDTHSLENTLNELQRANLLPIAVIATAGTTDF 275
Cdd:COG0076   158 ---GLPG-APRPRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNT 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 276 GAIDPIASIAHLCKKHNCYLHVDAAYGGALLVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVKDKRLLSF-LTY 354
Cdd:COG0076   234 GAIDPLAEIADIAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREaFSF 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 355 HADYLNPkaqAQAGVPDLINKSLQTTRRFDALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQLQAAQVPSLTT 434
Cdd:COG0076   314 HASYLGP---ADDGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELLAPPELNI 390

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2189084632 435 LVFRFNDSTLsqTQLDECNRTIRRALAQSSRAMIAATKVNNVQYLKFTLLNPHASIDSIDEVLNEICKIGEQ 506
Cdd:COG0076   391 VCFRYKPAGL--DEEDALNYALRDRLRARGRAFLSPTKLDGRVVLRLVVLNPRTTEDDVDALLDDLREAAAE 460
 
Name Accession Description Interval E-value
GadA COG0076
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ...
 36-506 9.43e-171

Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 439846 [Multi-domain]  Cd Length: 460  Bit Score: 490.11  E-value: 9.43e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632  36 DYAQLIQLGISTLSERIKEVNSPTSGVQPAQLQEEFAAiDLNTPLSDINQVLEELDHLYLKHAIYFHHQDYLAHLNCPVM 115
Cdd:COG0076     1 EFRALLHQALDLAADYLAGLDRPVFGPSPEELRAALDE-PLPEEGLPPEEALAELEDLVLPGSVDWNHPRFLAFVTGGTT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 116 LTSLLAELFSSSINTAVETWDQSAGATFIEQKVIDWTCQRIGYDEGADGVFTTGGTQSNLMALLLARELAGKLEPHSHtn 195
Cdd:COG0076    80 PAALAADLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLPEGAGGVFTSGGTEANLLALLAARDRALARRVRAE-- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 196 itsGLSSnAHRYRILCSEYSHFSIQKAAALLGLGHDAVISVACDENRCIDTHSLENTLNELQRANLLPIAVIATAGTTDF 275
Cdd:COG0076   158 ---GLPG-APRPRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNT 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 276 GAIDPIASIAHLCKKHNCYLHVDAAYGGALLVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVKDKRLLSF-LTY 354
Cdd:COG0076   234 GAIDPLAEIADIAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREaFSF 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 355 HADYLNPkaqAQAGVPDLINKSLQTTRRFDALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQLQAAQVPSLTT 434
Cdd:COG0076   314 HASYLGP---ADDGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELLAPPELNI 390

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2189084632 435 LVFRFNDSTLsqTQLDECNRTIRRALAQSSRAMIAATKVNNVQYLKFTLLNPHASIDSIDEVLNEICKIGEQ 506
Cdd:COG0076   391 VCFRYKPAGL--DEEDALNYALRDRLRARGRAFLSPTKLDGRVVLRLVVLNPRTTEDDVDALLDDLREAAAE 460
DOPA_deC_like cd06450
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 106-500 3.50e-104

DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.


Pssm-ID: 99743 [Multi-domain]  Cd Length: 345  Bit Score: 315.68  E-value: 3.50e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 106 YLAHLNCPVMLTSLLAELFSSSINTAVETWDQSAGATFIEQKVIDWTCQRIGYD-EGADGVFTTGGTQSNLMALLLAREL 184
Cdd:cd06450     1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLPsEDADGVFTSGGSESNLLALLAARDR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 185 AGKlephshtNITSGLSSNAHRYRILCSEYSHFSIQKAAALLGlghDAVISVACDENRCIDTHSLENTLNELQRANLLPI 264
Cdd:cd06450    81 ARK-------RLKAGGGRGIDKLVIVCSDQAHVSVEKAAAYLD---VKVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPI 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 265 AVIATAGTTDFGAIDPIASIAHLCKKHNCYLHVDAAYGGALLVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVK 344
Cdd:cd06450   151 MVVATAGTTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLVR 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 345 dkrllsfltyhadylnpkaqaqagvpdlinkslqttrrfdALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQL 424
Cdd:cd06450   231 ----------------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGF 270

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2189084632 425 QAAQVPSLTTLVFRFNDStlsqTQLDECNRTIRRALAQSSRAMIAATKVNNVQYLKFTLLNPHASIDSIDEVLNEI 500
Cdd:cd06450   271 ELLGEPNLSLVCFRLKPS----VKLDELNYDLSDRLNERGGWHVPATTLGGPNVLRFVVTNPLTTRDDADALLEDI 342
Pyridoxal_deC pfam00282
Pyridoxal-dependent decarboxylase conserved domain;
76-438 9.87e-56

Pyridoxal-dependent decarboxylase conserved domain;


Pssm-ID: 395219  Cd Length: 373  Bit Score: 191.09  E-value: 9.87e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632  76 LNTPLSDINQVLEELDHLYLKHAIYF----HHQDYLAHLNCPVMLTSLLAELFSSSINTAVETWDQSAGATFIEQKVIDW 151
Cdd:pfam00282   8 LPLAAPIIPEPELQIDGDIRRNLMPGvttwHSPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTELENVVMNW 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 152 TCQRIGYDE-----GADGVFTTGGTQSNLMALLLARElagKLEPHSHTNITSGLSSNAH-RYRILCSEYSHFSIQKAAAL 225
Cdd:pfam00282  88 LGEMLGLPAeflgqEGGGVLQPGSSESNLLALLAART---KWIKRMKAAGKPADSSGILaKLVAYTSDQAHSSIEKAALY 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 226 LGLGhdaVISVACDENRCIDTHSLENTLNELQRANLLPIAVIATAGTTDFGAIDPIASIAHLCKKHNCYLHVDAAYGGAL 305
Cdd:pfam00282 165 GGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAYGGSA 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 306 LVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVKDKRLL-SFLTYHADYLnpkaQAQAGVPDLINKSLQTTRRFD 384
Cdd:pfam00282 242 FICPEFRHWLFGIERADSITFNPHKWMLVLLDCSAVWVKDKEALqQAFQFNPLYL----GHTDSAYDTGHKQIPLSRRFR 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2189084632 385 ALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQLQAAQVPSLTTLVFR 438
Cdd:pfam00282 318 ILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGRFEICAEVGLGLVCFR 371
PLN02880 PLN02880
tyrosine decarboxylase
 60-486 5.91e-33

tyrosine decarboxylase


Pssm-ID: 215475 [Multi-domain]  Cd Length: 490  Bit Score: 131.18  E-value: 5.91e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632  60 SGVQPAQLQEEFAAIDLNTPLSdINQVLEELDHLYLKHAIYFHHQDYLAHLNCPVMLTSLLAELFSSSINTAVETWDQSA 139
Cdd:PLN02880   40 SQVQPGYLRELLPDSAPNQPET-LDQVLDDVQAKILPGVTHWQSPNYFAYYPSNSSVAGFLGEMLSAGLNIVGFSWITSP 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 140 GATFIEQKVIDWTCQRIGYDE------GADGVFTTGGTQSNLMALLLARELAgkLEPHSHTNItsglssnaHRYRILCSE 213
Cdd:PLN02880  119 AATELEMIVLDWLAKLLNLPEqflstgNGGGVIQGTASEAVLVVLLAARDRV--LRKVGKNAL--------EKLVVYASD 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 214 YSHFSIQKAAALLGLGHD--AVISVACDENRCIDTHSLENTLNELQRANLLPIAVIATAGTTDFGAIDPIASIAHLCKKH 291
Cdd:PLN02880  189 QTHSALQKACQIAGIHPEncRLLKTDSSTNYALAPELLSEAISTDLSSGLIPFFLCATVGTTSSTAVDPLLELGKIAKSN 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 292 NCYLHVDAAYGGALLVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVKDKR-LLSFLTYHADYLNPKAQAQAGVP 370
Cdd:PLN02880  269 GMWFHVDAAYAGSACICPEYRHYIDGVEEADSFNMNAHKWFLTNFDCSLLWVKDRNaLIQSLSTNPEFLKNKASQANSVV 348

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 371 DLINKSLQTTRRFDALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQLQAAQVPSLTTLVFRFNDSTLSQTQLD 450
Cdd:PLN02880  349 DYKDWQIPLGRRFRSLKLWMVLRLYGVENLQSYIRNHIKLAKEFEQLVAQDSRFEVVTPRIFSLVCFRLVPPKNNEDNGN 428

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 2189084632 451 ECNRTIRRALAQSSRAMIAATKVNNVQYLKFTLLNP 486
Cdd:PLN02880  429 KLNHDLLDAVNSSGKIFISHTVLSGKYVLRFAVGAP 464
 
Name Accession Description Interval E-value
GadA COG0076
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ...
 36-506 9.43e-171

Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 439846 [Multi-domain]  Cd Length: 460  Bit Score: 490.11  E-value: 9.43e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632  36 DYAQLIQLGISTLSERIKEVNSPTSGVQPAQLQEEFAAiDLNTPLSDINQVLEELDHLYLKHAIYFHHQDYLAHLNCPVM 115
Cdd:COG0076     1 EFRALLHQALDLAADYLAGLDRPVFGPSPEELRAALDE-PLPEEGLPPEEALAELEDLVLPGSVDWNHPRFLAFVTGGTT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 116 LTSLLAELFSSSINTAVETWDQSAGATFIEQKVIDWTCQRIGYDEGADGVFTTGGTQSNLMALLLARELAGKLEPHSHtn 195
Cdd:COG0076    80 PAALAADLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLPEGAGGVFTSGGTEANLLALLAARDRALARRVRAE-- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 196 itsGLSSnAHRYRILCSEYSHFSIQKAAALLGLGHDAVISVACDENRCIDTHSLENTLNELQRANLLPIAVIATAGTTDF 275
Cdd:COG0076   158 ---GLPG-APRPRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNT 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 276 GAIDPIASIAHLCKKHNCYLHVDAAYGGALLVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVKDKRLLSF-LTY 354
Cdd:COG0076   234 GAIDPLAEIADIAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREaFSF 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 355 HADYLNPkaqAQAGVPDLINKSLQTTRRFDALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQLQAAQVPSLTT 434
Cdd:COG0076   314 HASYLGP---ADDGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELLAPPELNI 390

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2189084632 435 LVFRFNDSTLsqTQLDECNRTIRRALAQSSRAMIAATKVNNVQYLKFTLLNPHASIDSIDEVLNEICKIGEQ 506
Cdd:COG0076   391 VCFRYKPAGL--DEEDALNYALRDRLRARGRAFLSPTKLDGRVVLRLVVLNPRTTEDDVDALLDDLREAAAE 460
DOPA_deC_like cd06450
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 106-500 3.50e-104

DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.


Pssm-ID: 99743 [Multi-domain]  Cd Length: 345  Bit Score: 315.68  E-value: 3.50e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 106 YLAHLNCPVMLTSLLAELFSSSINTAVETWDQSAGATFIEQKVIDWTCQRIGYD-EGADGVFTTGGTQSNLMALLLAREL 184
Cdd:cd06450     1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLPsEDADGVFTSGGSESNLLALLAARDR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 185 AGKlephshtNITSGLSSNAHRYRILCSEYSHFSIQKAAALLGlghDAVISVACDENRCIDTHSLENTLNELQRANLLPI 264
Cdd:cd06450    81 ARK-------RLKAGGGRGIDKLVIVCSDQAHVSVEKAAAYLD---VKVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPI 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 265 AVIATAGTTDFGAIDPIASIAHLCKKHNCYLHVDAAYGGALLVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVK 344
Cdd:cd06450   151 MVVATAGTTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLVR 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 345 dkrllsfltyhadylnpkaqaqagvpdlinkslqttrrfdALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQL 424
Cdd:cd06450   231 ----------------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGF 270

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2189084632 425 QAAQVPSLTTLVFRFNDStlsqTQLDECNRTIRRALAQSSRAMIAATKVNNVQYLKFTLLNPHASIDSIDEVLNEI 500
Cdd:cd06450   271 ELLGEPNLSLVCFRLKPS----VKLDELNYDLSDRLNERGGWHVPATTLGGPNVLRFVVTNPLTTRDDADALLEDI 342
Pyridoxal_deC pfam00282
Pyridoxal-dependent decarboxylase conserved domain;
76-438 9.87e-56

Pyridoxal-dependent decarboxylase conserved domain;


Pssm-ID: 395219  Cd Length: 373  Bit Score: 191.09  E-value: 9.87e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632  76 LNTPLSDINQVLEELDHLYLKHAIYF----HHQDYLAHLNCPVMLTSLLAELFSSSINTAVETWDQSAGATFIEQKVIDW 151
Cdd:pfam00282   8 LPLAAPIIPEPELQIDGDIRRNLMPGvttwHSPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTELENVVMNW 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 152 TCQRIGYDE-----GADGVFTTGGTQSNLMALLLARElagKLEPHSHTNITSGLSSNAH-RYRILCSEYSHFSIQKAAAL 225
Cdd:pfam00282  88 LGEMLGLPAeflgqEGGGVLQPGSSESNLLALLAART---KWIKRMKAAGKPADSSGILaKLVAYTSDQAHSSIEKAALY 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 226 LGLGhdaVISVACDENRCIDTHSLENTLNELQRANLLPIAVIATAGTTDFGAIDPIASIAHLCKKHNCYLHVDAAYGGAL 305
Cdd:pfam00282 165 GGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAYGGSA 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 306 LVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVKDKRLL-SFLTYHADYLnpkaQAQAGVPDLINKSLQTTRRFD 384
Cdd:pfam00282 242 FICPEFRHWLFGIERADSITFNPHKWMLVLLDCSAVWVKDKEALqQAFQFNPLYL----GHTDSAYDTGHKQIPLSRRFR 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2189084632 385 ALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQLQAAQVPSLTTLVFR 438
Cdd:pfam00282 318 ILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGRFEICAEVGLGLVCFR 371
PLN02880 PLN02880
tyrosine decarboxylase
 60-486 5.91e-33

tyrosine decarboxylase


Pssm-ID: 215475 [Multi-domain]  Cd Length: 490  Bit Score: 131.18  E-value: 5.91e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632  60 SGVQPAQLQEEFAAIDLNTPLSdINQVLEELDHLYLKHAIYFHHQDYLAHLNCPVMLTSLLAELFSSSINTAVETWDQSA 139
Cdd:PLN02880   40 SQVQPGYLRELLPDSAPNQPET-LDQVLDDVQAKILPGVTHWQSPNYFAYYPSNSSVAGFLGEMLSAGLNIVGFSWITSP 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 140 GATFIEQKVIDWTCQRIGYDE------GADGVFTTGGTQSNLMALLLARELAgkLEPHSHTNItsglssnaHRYRILCSE 213
Cdd:PLN02880  119 AATELEMIVLDWLAKLLNLPEqflstgNGGGVIQGTASEAVLVVLLAARDRV--LRKVGKNAL--------EKLVVYASD 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 214 YSHFSIQKAAALLGLGHD--AVISVACDENRCIDTHSLENTLNELQRANLLPIAVIATAGTTDFGAIDPIASIAHLCKKH 291
Cdd:PLN02880  189 QTHSALQKACQIAGIHPEncRLLKTDSSTNYALAPELLSEAISTDLSSGLIPFFLCATVGTTSSTAVDPLLELGKIAKSN 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 292 NCYLHVDAAYGGALLVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVKDKR-LLSFLTYHADYLNPKAQAQAGVP 370
Cdd:PLN02880  269 GMWFHVDAAYAGSACICPEYRHYIDGVEEADSFNMNAHKWFLTNFDCSLLWVKDRNaLIQSLSTNPEFLKNKASQANSVV 348

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 371 DLINKSLQTTRRFDALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQLQAAQVPSLTTLVFRFNDSTLSQTQLD 450
Cdd:PLN02880  349 DYKDWQIPLGRRFRSLKLWMVLRLYGVENLQSYIRNHIKLAKEFEQLVAQDSRFEVVTPRIFSLVCFRLVPPKNNEDNGN 428

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 2189084632 451 ECNRTIRRALAQSSRAMIAATKVNNVQYLKFTLLNP 486
Cdd:PLN02880  429 KLNHDLLDAVNSSGKIFISHTVLSGKYVLRFAVGAP 464
PLN02590 PLN02590
probable tyrosine decarboxylase
 60-486 2.01e-32

probable tyrosine decarboxylase


Pssm-ID: 178200 [Multi-domain]  Cd Length: 539  Bit Score: 130.60  E-value: 2.01e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632  60 SGVQPAQLQEEFAAIDLNTPLSdINQVLEELDHLYLKHAIYFHHQDYLAHLNCPVMLTSLLAELFSSSINTAVETWDQSA 139
Cdd:PLN02590   88 SQVQPGYLRDMLPDSAPERPES-LKELLDDVSKKIMPGITHWQSPSYFAYYASSTSVAGFLGEMLNAGLSVVGFTWLTSP 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 140 GATFIEQKVIDWTCQRIGYDE------GADGVFTTGGTQSNLMALLLARElagKLEPHSHTNITSGLSSNAhryrilcSE 213
Cdd:PLN02590  167 AATELEIIVLDWLAKLLQLPDhflstgNGGGVIQGTGCEAVLVVVLAARD---RILKKVGKTLLPQLVVYG-------SD 236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 214 YSHFSIQKAAALLGLGHDAVISVACDE--NRCIDTHSLENTLNELQRANLLPIAVIATAGTTDFGAIDPIASIAHLCKKH 291
Cdd:PLN02590  237 QTHSSFRKACLIGGIHEENIRLLKTDSstNYGMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKY 316

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 292 NCYLHVDAAYGGALLVSQRHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVKDK-RLLSFLTYHADYLNPKAQAQAGVP 370
Cdd:PLN02590  317 GIWLHVDAAYAGNACICPEYRKFIDGIENADSFNMNAHKWLFANQTCSPLWVKDRySLIDALKTNPEYLEFKVSKKDTVV 396

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 371 DLINKSLQTTRRFDALKLWLSLRTEGPDAIGAMFDTLLEKTQQVYQRLTRHSQLQAAQVPSLTTLVFRFNDSTLSQTQLD 450
Cdd:PLN02590  397 NYKDWQISLSRRFRSLKLWMVLRLYGSENLRNFIRDHVNLAKHFEDYVAQDPSFEVVTTRYFSLVCFRLAPVDGDEDQCN 476

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 2189084632 451 ECNRTIRRALAQSSRAMIAATKVNNVQYLKFTLLNP 486
Cdd:PLN02590  477 ERNRELLAAVNSTGKIFISHTALSGKFVLRFAVGAP 512
PRK02769 PRK02769
histidine decarboxylase; Provisional
 84-437 2.75e-23

histidine decarboxylase; Provisional


Pssm-ID: 235068 [Multi-domain]  Cd Length: 380  Bit Score: 101.66  E-value: 2.75e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632  84 NQVLEELDHLYLKhaIYFHHQDYLAHLNCPVMLTSLLAELFSSSINTAVETWDQSAGA--TF-IEQKVIDW--------T 152
Cdd:PRK02769    5 PADQKEIEDFWLY--LRHNQYFNVGYPEAADFDYSALKRFFSFSINNCGDPYSKSNYPlnSFdFERDVMNFfaelfkipF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 153 CQRIGYdegadgvFTTGGTQSNLMALLLARELagklephshtnitsglSSNAHRYRilcSEYSHFSIQKAAALLGLGHDA 232
Cdd:PRK02769   83 NESWGY-------ITNGGTEGNLYGCYLAREL----------------FPDGTLYY---SKDTHYSVSKIARLLRIKSRV 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 233 VISVACDEnrcIDTHSLENTLNELQRANllPIaVIATAGTTDFGAIDPIASIAHLCKKH---NCYLHVDAAYGGALLVSQ 309
Cdd:PRK02769  137 ITSLPNGE---IDYDDLISKIKENKNQP--PI-IFANIGTTMTGAIDNIKEIQEILKKIgidDYYIHADAALSGMILPFV 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 310 RHNERLLGIDLADSVSIDFHKTFFQPVCCSALLVKDKRLLSFLTyHADYLNPKAQAQAGvpdlinkslqtTRR-FDALKL 388
Cdd:PRK02769  211 NNPPPFSFADGIDSIAISGHKFIGSPMPCGIVLAKKKYVERISV-DVDYIGSRDQTISG-----------SRNgHTALLL 278

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2189084632 389 WLSLRTEGPDAIGAMFDTLLEKTQQVYQRltrhsqLQAAQVPSL-----TTLVF 437
Cdd:PRK02769  279 WAAIRSLGSKGLRQRVQHCLDMAQYAVDR------LQANGIPAWrnpnsITVVF 326
NifS COG1104
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino ...
 165-330 4.32e-08

Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino acid transport and metabolism];


Pssm-ID: 440721 [Multi-domain]  Cd Length: 381  Bit Score: 55.05  E-value: 4.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 165 VFTTGGTQSNLMALL-LARELAGKlephshtnitsglssnahRYRILCSEYSHFSIQKAAALL-GLGHDaVISVACDENR 242
Cdd:COG1104    66 IFTSGGTEANNLAIKgAARAYRKK------------------GKHIITSAIEHPAVLETARFLeKEGFE-VTYLPVDEDG 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 243 CIDTHSLENTLnelqRANLLPIAVIA----TagttdfGAIDPIASIAHLCKKHNCYLHVDA--AYG-GALLVSQrhnerl 315
Cdd:COG1104   127 RVDLEALEAAL----RPDTALVSVMHanneT------GTIQPIAEIAEIAKEHGVLFHTDAvqAVGkIPVDVKE------ 190

                         170
                  ....*....|....*
gi 2189084632 316 LGIDLAdsvSIDFHK 330
Cdd:COG1104   191 LGVDLL---SLSAHK 202
PLN03032 PLN03032
serine decarboxylase; Provisional
 109-419 7.19e-08

serine decarboxylase; Provisional


Pssm-ID: 166673 [Multi-domain]  Cd Length: 374  Bit Score: 54.45  E-value: 7.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 109 HLNCPVMLT---SLLAELFSSSINtavetwdqSAGATFIEQK-----------VIDWTCQRIGYDEGAD-GVFTTGGTQS 173
Cdd:PLN03032   26 HFGYPYNLDfdyGELSQLMKYSIN--------NLGDPFIESNygvhsrqfevgVLDWFARLWELEKDEYwGYITTCGTEG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 174 NLMALLLARElagklephshtNITSGLssnahryrILCSEYSHFSIQKAAALLGLGHDAVISVACDENRCIDTHSlentl 253
Cdd:PLN03032   98 NLHGILVGRE-----------VFPDGI--------LYASRESHYSVFKAARMYRMEAVKVPTLPSGEIDYDDLER----- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 254 nELQRANLLPIAVIATAGTTDFGAIDPIASIAHLCKK-----HNCYLHVDAAYGGALLVSQRHNERLLGIDLADSVSIDF 328
Cdd:PLN03032  154 -ALAKNRDKPAILNVNIGTTVKGAVDDLDRILRILKElgyteDRFYIHCDGALFGLMMPFVSRAPEVTFRKPIGSVSVSG 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 329 HKTFFQPVCCSALLVKDKRLLSfLTYHADYLNPKaqaqagvpdliNKSLQTTRRFDA-LKLWLSLRTEGPDAIGAMFDTL 407
Cdd:PLN03032  233 HKFLGCPMPCGVALTRKKHVKA-LSQNVEYLNSR-----------DATIMGSRNGHApLYLWYTLRRKGYRGIKRDVQHC 300

                         330
                  ....*....|..
gi 2189084632 408 LEKTQQVYQRLT 419
Cdd:PLN03032  301 MRNAHYLKDRLT 312
PRK02948 PRK02948
IscS subfamily cysteine desulfurase;
162-332 1.50e-07

IscS subfamily cysteine desulfurase;


Pssm-ID: 179511 [Multi-domain]  Cd Length: 381  Bit Score: 53.58  E-value: 1.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 162 ADGV-FTTGGTQSNLMALllaRELAgklephshtnitsglssNAHRY---RILCSEYSHFSIQKAAALL-GLGHDaVISV 236
Cdd:PRK02948   60 EQGIyFTSGGTESNYLAI---QSLL-----------------NALPQnkkHIITTPMEHASIHSYFQSLeSQGYT-VTEI 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 237 ACDENRCIDTHSLENTLNE------LQRANllpiaviatagtTDFGAIDPIASIAHLCKKHNCYLHVDAAYGGALLvsqR 310
Cdd:PRK02948  119 PVDKSGLIRLVDLERAITPdtvlasIQHAN------------SEIGTIQPIAEIGALLKKYNVLFHSDCVQTFGKL---P 183

                         170       180
                  ....*....|....*....|..
gi 2189084632 311 HNERLLGIdlaDSVSIDFHKTF 332
Cdd:PRK02948  184 IDVFEMGI---DSLSVSAHKIY 202
Aminotran_5 pfam00266
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ...
 165-319 8.41e-07

Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.


Pssm-ID: 425567 [Multi-domain]  Cd Length: 368  Bit Score: 51.09  E-value: 8.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 165 VFTTGGTQS-NLMALLLARELAGKLEphshtnitsglssnahryrILCSEYSHFSIQKAAALLGLGHDAVISVA-CDENR 242
Cdd:pfam00266  65 IFTSGTTEAiNLVALSLGRSLKPGDE-------------------IVITEMEHHANLVPWQELAKRTGARVRVLpLDEDG 125

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2189084632 243 CIDTHSLENTLNElqRANLLPIaviaTAGTTDFGAIDPIASIAHLCKKHNCYLHVDAAYGgalLVSQRHNERLLGID 319
Cdd:pfam00266 126 LLDLDELEKLITP--KTKLVAI----THVSNVTGTIQPVPEIGKLAHQYGALVLVDAAQA---IGHRPIDVQKLGVD 193
AAT_I cd01494
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ...
 158-344 1.98e-06

Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).


Pssm-ID: 99742 [Multi-domain]  Cd Length: 170  Bit Score: 48.15  E-value: 1.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 158 YDEGADG-VFTTGGTQSNLMALLLARElagklephshtnitsglssnaHRYRILCSEYSHFS-IQKAAALLGLGhdaVIS 235
Cdd:cd01494    13 LQPGNDKaVFVPSGTGANEAALLALLG---------------------PGDEVIVDANGHGSrYWVAAELAGAK---PVP 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 236 VACDEN--RCIDTHSLENTLNELQranllPIAVIATAGTTDFGAIDPIASIAHLCKKHNCYLHVDAAYGGAllvSQRHNE 313
Cdd:cd01494    69 VPVDDAgyGGLDVAILEELKAKPN-----VALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGG---ASPAPG 140

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2189084632 314 RLLGIDLADSVSIDFHKTFFQPVcCSALLVK 344
Cdd:cd01494   141 VLIPEGGADVVTFSLHKNLGGEG-GGVVIVK 170
TA_like cd06502
Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP) ...
 160-359 3.32e-05

Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a secondary glycine biosynthetic pathway.


Pssm-ID: 99748 [Multi-domain]  Cd Length: 338  Bit Score: 46.17  E-value: 3.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 160 EGADGVFTTGGTQSNLMALllarelagklepHSHTnitsglssnaHRY-RILCSEYSHFSIQKAAALLGLGhdAVISVAC 238
Cdd:cd06502    46 GKEAALFVPSGTAANQLAL------------AAHT----------QPGgSVICHETAHIYTDEAGAPEFLS--GVKLLPV 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 239 D-ENRCIDTHSLENTLNELQRANLLPIAVIATAGTTDFGAIDP---IASIAHLCKKHNCYLHVD--------AAYGGALL 306
Cdd:cd06502   102 PgENGKLTPEDLEAAIRPRDDIHFPPPSLVSLENTTEGGTVYPldeLKAISALAKENGLPLHLDgarlanaaAALGVALK 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2189084632 307 VSQRHnerllgidlADSVSIDFHKTFFQPVccSALLVKDKRLLSfltyHADYL 359
Cdd:cd06502   182 TYKSG---------VDSVSFCLSKGGGAPV--GAVVVGNRDFIA----RARRR 219
PLN02651 PLN02651
cysteine desulfurase
 165-344 6.36e-05

cysteine desulfurase


Pssm-ID: 178257 [Multi-domain]  Cd Length: 364  Bit Score: 45.42  E-value: 6.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 165 VFTTGGTQSNLMALLLARELAGKLEPHSHTNITSG---LSSNAHRYRILCsEYSHFSIQKAaallGLGHDAVISVACDEN 241
Cdd:PLN02651   64 IFTSGATESNNLAIKGVMHFYKDKKKHVITTQTEHkcvLDSCRHLQQEGF-EVTYLPVKSD----GLVDLDELAAAIRPD 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 242 RCIDTHSLENtlNELqranllpiaviatagttdfGAIDPIASIAHLCKKHNCYLHVDAAYG-GALLVsqrhNERLLGIDL 320
Cdd:PLN02651  139 TALVSVMAVN--NEI-------------------GVIQPVEEIGELCREKKVLFHTDAAQAvGKIPV----DVDDLGVDL 193

                         170       180
                  ....*....|....*....|....
gi 2189084632 321 adsVSIDFHKtFFQPVCCSALLVK 344
Cdd:PLN02651  194 ---MSISGHK-IYGPKGVGALYVR 213
Beta_elim_lyase pfam01212
Beta-eliminating lyase;
164-336 3.57e-04

Beta-eliminating lyase;


Pssm-ID: 426128 [Multi-domain]  Cd Length: 288  Bit Score: 42.59  E-value: 3.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 164 GVFTTGGTQSNLMALLLArelagkLEPHshtnitsglssnahrYRILCSEYSH--FSIQKAAALLGLGHdaVISVACDEN 241
Cdd:pfam01212  50 ALFVPSGTAANQLALMAH------CQRG---------------DEVICGEPAHihFDETGGHAELGGVQ--PRPLDGDEA 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 242 RCIDTHSLENTLNELQRANLLPIAVIATAGTTDFGA-----IDPIASIAHLCKKHNCYLHVDAAyggallvsqrhneRL- 315
Cdd:pfam01212 107 GNMDLEDLEAAIREVGADIFPPTGLISLENTHNSAGgqvvsLENLREIAALAREHGIPVHLDGA-------------RFa 173

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2189084632 316 -----LGIDL------ADSVSIDFHKTFFQPV 336
Cdd:pfam01212 174 naavaLGVIVkeitsyADSVTMCLSKGLGAPV 205
PRK14012 PRK14012
IscS subfamily cysteine desulfurase;
161-346 5.93e-03

IscS subfamily cysteine desulfurase;


Pssm-ID: 184450 [Multi-domain]  Cd Length: 404  Bit Score: 39.16  E-value: 5.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 161 GADG---VFTTGGTQSNLMALLLARELAGKLEPHShtnITSglssnahryrilCSEyshfsiqkaaallglgHDAVIsva 237
Cdd:PRK14012   63 GADPreiVFTSGATESDNLAIKGAAHFYQKKGKHI---ITS------------KTE----------------HKAVL--- 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2189084632 238 cDENRCIDTHSLENTLNELQRANLLPIAVIATAGTTD------------FGAIDPIASIAHLCKKHNCYLHVDAAYG-GA 304
Cdd:PRK14012  109 -DTCRQLEREGFEVTYLDPQSNGIIDLEKLEAAMRDDtilvsimhvnneIGVIQDIAAIGEICRERGIIFHVDAAQSvGK 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2189084632 305 LLVsqrhNERLLGIDLAdsvSIDFHKTfFQPVCCSALLVKDK 346
Cdd:PRK14012  188 VPI----DLSKLKVDLM---SFSAHKI-YGPKGIGALYVRRK 221
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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