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Conserved domains on  [gi|2190500896|ref|WP_237701963|]
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F0F1 ATP synthase subunit A [Salinibacter ruber]

Protein Classification

FoF1 ATP synthase subunit a( domain architecture ID 116)

FoF1 ATP synthase subunit a is part of the membrane proton channel (Fo complex) of the F-type ATPase that produces ATP from ADP in the presence of a proton gradient across the membrane; it plays a direct role in the translocation of protons across the membrane

Gene Ontology:  GO:0045263|GO:0015078|GO:0015986
PubMed:  11533110|12370007|30901262

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP-synt_Fo_a_6 super family cl00413
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 123-367 2.93e-66

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


The actual alignment was detected with superfamily member PRK13419:

Pssm-ID: 469762  Cd Length: 342  Bit Score: 213.84  E-value: 2.93e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 123 DLSISRHLIFGLLAMLIVLGVFIALAQRYKKEHDRpEAPKGVFqNMMEVLVVFVRDEIAKPNIPDGKWRtFLPYLLTAFF 202
Cdd:PRK13419  103 DISITKHVVMMWIASAILLVVFLAAGRKYKKMTKS-QAPKGLA-NAMEALVEFIRLDVAKSNIGHGYEK-FLPYLLTVFF 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 203 FILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLL-----YGSSDYYKELLTGPPDApvlIRIILVPIEIIGLVMRHL 277
Cdd:PRK13419  180 FILVCNLLGLVPYGATATGNINVTLTLAVFTFFITQYaaikaHGIKGYLAHLTGGTHWS---LWIIMIPIEFIGLFTKPF 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 278 ALAIRLFANMMGGSLIIFSLIGLVFMMNvimgeaAAWSTTVISIGFTVFILLLKLLVAFIQAYVFTILSALFIGMAVEEH 357
Cdd:PRK13419  257 ALTVRLFANMTAGHIVILSLIFISFILK------SYIVAVAVSVPFAIFIYLLELFVAFLQAYIFTMLSALFIGLATAHE 330

                         250
                  ....*....|
gi 2190500896 358 HPDGEEAAEP 367
Cdd:PRK13419  331 GHDEEHAEAH 340
 
Name Accession Description Interval E-value
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 123-367 2.93e-66

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 213.84  E-value: 2.93e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 123 DLSISRHLIFGLLAMLIVLGVFIALAQRYKKEHDRpEAPKGVFqNMMEVLVVFVRDEIAKPNIPDGKWRtFLPYLLTAFF 202
Cdd:PRK13419  103 DISITKHVVMMWIASAILLVVFLAAGRKYKKMTKS-QAPKGLA-NAMEALVEFIRLDVAKSNIGHGYEK-FLPYLLTVFF 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 203 FILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLL-----YGSSDYYKELLTGPPDApvlIRIILVPIEIIGLVMRHL 277
Cdd:PRK13419  180 FILVCNLLGLVPYGATATGNINVTLTLAVFTFFITQYaaikaHGIKGYLAHLTGGTHWS---LWIIMIPIEFIGLFTKPF 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 278 ALAIRLFANMMGGSLIIFSLIGLVFMMNvimgeaAAWSTTVISIGFTVFILLLKLLVAFIQAYVFTILSALFIGMAVEEH 357
Cdd:PRK13419  257 ALTVRLFANMTAGHIVILSLIFISFILK------SYIVAVAVSVPFAIFIYLLELFVAFLQAYIFTMLSALFIGLATAHE 330

                         250
                  ....*....|
gi 2190500896 358 HPDGEEAAEP 367
Cdd:PRK13419  331 GHDEEHAEAH 340
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 128-356 1.61e-60

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 194.52  E-value: 1.61e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 128 RHLIFGLLAMLIVLGVFIALAQRYKKehdrpeAPKGvFQNMMEVLVVFVRDEIAKpNIPdGKWRTFLPYLLTAFFFILVA 207
Cdd:COG0356     1 DTVLMSWLAMLLLLLLFLLATRKLKL------VPGG-LQNFVEMLVEFVRNQVKD-TIG-KKGRKFAPLLLTLFLFILVS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 208 NILGLVPFAGAATSNIAVTGVMAIMTFSIVLLY-----GSSDYYKELLTGPPdapVLIRIILVPIEIIGLVMRHLALAIR 282
Cdd:COG0356    72 NLLGLIPGLFPPTADINVTLALALIVFVLVHYYgikkkGLGGYLKHLFFPPF---PWLAPLMLPIEIISELARPLSLSLR 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2190500896 283 LFANMMGGSLIIFSLIGLVFMmnvimgeaaaWSTTVISIGFTVFILLLKLLVAFIQAYVFTILSALFIGMAVEE 356
Cdd:COG0356   149 LFGNMFAGHIILLLLAGLAPF----------LLLGVLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
130-351 7.69e-60

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 193.09  E-value: 7.69e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 130 LIFGLLAMLIVLGVFIALAQRYKKEhdrpeAPKGvFQNMMEVLVVFVrDEIAKPNIPDGKWRTFLPYLLTAFFFILVANI 209
Cdd:pfam00119   1 LLMSLIVALILLLFLLLATRKTKKL-----VPGR-LQNFVEMLVEFV-DNIVKDNIGKKKGRKFFPLLLTLFFFILVSNL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 210 LGLV---PFAGAATSNIAVTGVMAIMTFSIVLLYG-----SSDYYKELLtgPPDAPVLIRIILVPIEIIGLVMRHLALAI 281
Cdd:pfam00119  74 LGLIpksPGGFTVTADINVTLALALIVFLLVHYYGikkhgLGGYFKKLF--VPPVPLPLVPLLLPIEIISEFARPVSLSL 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 282 RLFANMMGGSLIIFSLIGLVFMMNVIMgeaaaWSTTVISIGFTVFILLLKLLVAFIQAYVFTILSALFIG 351
Cdd:pfam00119 152 RLFGNMLAGHLLLLLLAGLIFALLSAG-----FLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 190-351 5.43e-47

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 157.56  E-value: 5.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 190 WRTFLPYLLTAFFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSD----YYKELLtgPPDAPVLIRIILV 265
Cdd:cd00310     1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKhglgFFLHFL--PPGTPLPLAPLMV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 266 PIEIIGLVMRHLALAIRLFANMMGGSLIIFSLIGLVFMMNVIMGeaaawsttVISIGFTVFILLLKLLVAFIQAYVFTIL 345
Cdd:cd00310    79 PIELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVG--------LLPLLLPVALTLLELFVAFIQAYVFTLL 150


                  ....*.
gi 2190500896 346 SALFIG 351
Cdd:cd00310   151 TAVYIS 156
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 124-350 1.12e-33

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 125.01  E-value: 1.12e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 124 LSISRHLIFGLLAMLIVLGVFIALAQRykkehdrpeAPKGvFQNMMEVLVVFVRDEIaKPNIPdGKWRTFLPYLLTAFFF 203
Cdd:TIGR01131  13 FSLTLLSLILLLSLLIFLISSSLSRWL---------IPSR-WQNLMESIYEFVLSIV-KSQIG-GKKGKFFPLIFTLFLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 204 ILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSDYYKELLTG--PPDAPVLIRIILVPIEIIGLVMRHLALAI 281
Cdd:TIGR01131  81 ILISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHlvPSGTPLPLIPFLVIIETISYLARPISLSV 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2190500896 282 RLFANMMGGSLIIFSLIGLVFMMnvimgeaaaWSTTVISIGFTVFILL--LKLLVAFIQAYVFTILSALFI 350
Cdd:TIGR01131 161 RLFANISAGHLLLTLLSGLLFSL---------MSSAIFALLLLILVALiiLEIFVAFIQAYVFTLLTCLYL 222
 
Name Accession Description Interval E-value
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 123-367 2.93e-66

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 213.84  E-value: 2.93e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 123 DLSISRHLIFGLLAMLIVLGVFIALAQRYKKEHDRpEAPKGVFqNMMEVLVVFVRDEIAKPNIPDGKWRtFLPYLLTAFF 202
Cdd:PRK13419  103 DISITKHVVMMWIASAILLVVFLAAGRKYKKMTKS-QAPKGLA-NAMEALVEFIRLDVAKSNIGHGYEK-FLPYLLTVFF 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 203 FILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLL-----YGSSDYYKELLTGPPDApvlIRIILVPIEIIGLVMRHL 277
Cdd:PRK13419  180 FILVCNLLGLVPYGATATGNINVTLTLAVFTFFITQYaaikaHGIKGYLAHLTGGTHWS---LWIIMIPIEFIGLFTKPF 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 278 ALAIRLFANMMGGSLIIFSLIGLVFMMNvimgeaAAWSTTVISIGFTVFILLLKLLVAFIQAYVFTILSALFIGMAVEEH 357
Cdd:PRK13419  257 ALTVRLFANMTAGHIVILSLIFISFILK------SYIVAVAVSVPFAIFIYLLELFVAFLQAYIFTMLSALFIGLATAHE 330

                         250
                  ....*....|
gi 2190500896 358 HPDGEEAAEP 367
Cdd:PRK13419  331 GHDEEHAEAH 340
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 128-356 1.61e-60

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 194.52  E-value: 1.61e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 128 RHLIFGLLAMLIVLGVFIALAQRYKKehdrpeAPKGvFQNMMEVLVVFVRDEIAKpNIPdGKWRTFLPYLLTAFFFILVA 207
Cdd:COG0356     1 DTVLMSWLAMLLLLLLFLLATRKLKL------VPGG-LQNFVEMLVEFVRNQVKD-TIG-KKGRKFAPLLLTLFLFILVS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 208 NILGLVPFAGAATSNIAVTGVMAIMTFSIVLLY-----GSSDYYKELLTGPPdapVLIRIILVPIEIIGLVMRHLALAIR 282
Cdd:COG0356    72 NLLGLIPGLFPPTADINVTLALALIVFVLVHYYgikkkGLGGYLKHLFFPPF---PWLAPLMLPIEIISELARPLSLSLR 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2190500896 283 LFANMMGGSLIIFSLIGLVFMmnvimgeaaaWSTTVISIGFTVFILLLKLLVAFIQAYVFTILSALFIGMAVEE 356
Cdd:COG0356   149 LFGNMFAGHIILLLLAGLAPF----------LLLGVLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
130-351 7.69e-60

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 193.09  E-value: 7.69e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 130 LIFGLLAMLIVLGVFIALAQRYKKEhdrpeAPKGvFQNMMEVLVVFVrDEIAKPNIPDGKWRTFLPYLLTAFFFILVANI 209
Cdd:pfam00119   1 LLMSLIVALILLLFLLLATRKTKKL-----VPGR-LQNFVEMLVEFV-DNIVKDNIGKKKGRKFFPLLLTLFFFILVSNL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 210 LGLV---PFAGAATSNIAVTGVMAIMTFSIVLLYG-----SSDYYKELLtgPPDAPVLIRIILVPIEIIGLVMRHLALAI 281
Cdd:pfam00119  74 LGLIpksPGGFTVTADINVTLALALIVFLLVHYYGikkhgLGGYFKKLF--VPPVPLPLVPLLLPIEIISEFARPVSLSL 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 282 RLFANMMGGSLIIFSLIGLVFMMNVIMgeaaaWSTTVISIGFTVFILLLKLLVAFIQAYVFTILSALFIG 351
Cdd:pfam00119 152 RLFGNMLAGHLLLLLLAGLIFALLSAG-----FLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 190-351 5.43e-47

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 157.56  E-value: 5.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 190 WRTFLPYLLTAFFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSD----YYKELLtgPPDAPVLIRIILV 265
Cdd:cd00310     1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKhglgFFLHFL--PPGTPLPLAPLMV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 266 PIEIIGLVMRHLALAIRLFANMMGGSLIIFSLIGLVFMMNVIMGeaaawsttVISIGFTVFILLLKLLVAFIQAYVFTIL 345
Cdd:cd00310    79 PIELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVG--------LLPLLLPVALTLLELFVAFIQAYVFTLL 150


                  ....*.
gi 2190500896 346 SALFIG 351
Cdd:cd00310   151 TAVYIS 156
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 130-358 2.16e-44

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 153.41  E-value: 2.16e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 130 LIFGLLAMLIVLGVFIALAQRykkehDRPEAPKGvFQNMMEVLVVFVRDeIAKPNIpDGKWRTFLPYLLTAFFFILVANI 209
Cdd:PRK05815   17 LLLSVLLGVLILLLFALVATR-----KLSGVPGG-LQNFVEMIVEFVRG-QVKDNI-GGKGKKFAPLAFTLFLFILLMNL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 210 LGLVP-FAGAATSNIAVTGVMAIMTFSIVLLYGS-----SDYYKELLTGPPdapvlirIILVPIEIIGLVMRHLALAIRL 283
Cdd:PRK05815   89 LGLIPyLLFPPTADINVTLALALIVFVLVIYYGIkkkglGGYLKEFYLQPH-------PLLLPIEIISEFSRPISLSLRL 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2190500896 284 FANMMGGSlIIFSLIGLVFMMNVIMGeaaawsttVISIGFTVFILLLKLLVAFIQAYVFTILSALFIGMAVEEHH 358
Cdd:PRK05815  162 FGNMLAGE-LILALIALLGGAGLLLA--------LAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEEH 227
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 124-350 1.12e-33

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 125.01  E-value: 1.12e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 124 LSISRHLIFGLLAMLIVLGVFIALAQRykkehdrpeAPKGvFQNMMEVLVVFVRDEIaKPNIPdGKWRTFLPYLLTAFFF 203
Cdd:TIGR01131  13 FSLTLLSLILLLSLLIFLISSSLSRWL---------IPSR-WQNLMESIYEFVLSIV-KSQIG-GKKGKFFPLIFTLFLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 204 ILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSDYYKELLTG--PPDAPVLIRIILVPIEIIGLVMRHLALAI 281
Cdd:TIGR01131  81 ILISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHlvPSGTPLPLIPFLVIIETISYLARPISLSV 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2190500896 282 RLFANMMGGSLIIFSLIGLVFMMnvimgeaaaWSTTVISIGFTVFILL--LKLLVAFIQAYVFTILSALFI 350
Cdd:TIGR01131 161 RLFANISAGHLLLTLLSGLLFSL---------MSSAIFALLLLILVALiiLEIFVAFIQAYVFTLLTCLYL 222
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 110-357 1.97e-23

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 99.96  E-value: 1.97e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 110 HSTAVRTSGEVVADLSISRHLIFGLLAMLIVLGVFIALAQRYKKEhdrPEAPKGVFQNMMEVLVVFVRDEIAKPNIpDGK 189
Cdd:PRK13417   78 HETGKRFHYVGGFDMHITKRVTMMWIVAFFLFLIFIPAANIIAKN---PLKVQSRFANTVEVFVNFLRKDIVDESM-HGH 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 190 WRTFLPYLLTAFFFILVANILGLVPFAGAAT-----------------------------SNIAVTG----VMAIMTFSI 236
Cdd:PRK13417  154 GHSYYHYIFTLFFFILFCNLMGLVPSVGELTvvasdygglvalgvmdhtphalptfakvwSGITVTGdisvTMTLALLTM 233

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 237 VLLYGSSDYYKELL----TGPPDAPVLIRIILVPIE-IIGLVMRHLALAIRLFANMMGGSLIIFSLIGLVFMMNvimgea 311
Cdd:PRK13417  234 FLIYGAGFSYQGPKfiwhSVPNGVPLLLYPIMWPLEfIVSPMAKTFALTVRLLANMTAGHVIILALMGFIFQFQ------ 307

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 2190500896 312 aAWSTTVISIGFTVFILLLKLLVAFIQAYVFTILSALFIGMAVEEH 357
Cdd:PRK13417  308 -SWGIVPVSVIGSGLIYVLEIFVAFLQAYIFVLLTSLFVGLSMHRH 352
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 201-350 9.57e-22

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 92.54  E-value: 9.57e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 201 FFFILVANILGLVPFAGAATSNIAVTGVMAI---MTFsivLLYGSSDYYKELLTG--PPDAPVLIRIILVPIEIIGLVMR 275
Cdd:MTH00157   76 FSFILFNNFLGLFPYIFTSTSHLSLTLSLALplwLSF---MLFGWINNTNHMFAHlvPQGTPPILMPFMVLIETISNLIR 152

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2190500896 276 HLALAIRLFANMMGGSLIIfSLIGLVFMMNvimgeaaawSTTVISIGFTVFILL--LKLLVAFIQAYVFTILSALFI 350
Cdd:MTH00157  153 PGTLAVRLAANMIAGHLLL-TLLGNTGPSL---------SSMILSILILIQILLliLESAVAIIQSYVFSVLSTLYS 219
PRK13420 PRK13420
F0F1 ATP synthase subunit A; Provisional
 137-357 1.53e-18

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237382 [Multi-domain]  Cd Length: 226  Bit Score: 83.64  E-value: 1.53e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 137 MLIVLGVFIALAQRykkehdRPEAPKGVFQNMMEVLVVFVRDEIAkpNIPDGKWRTFLPYLLTAFFFILVANILGLVPFA 216
Cdd:PRK13420   26 IMIVLVLASWLTTR------RLSLDPGRFQVALEGVVSTIEDAIK--EVLPRHARLVLPFVGTLWIFILVANLIGLIPGF 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 217 GAATSNIAVTGVMAIMTFSIVLLYGS-----SDYYKELLTGPPdapvliriILVPIEIIGLVMRHLALAIRLFANMMggS 291
Cdd:PRK13420   98 HSPTADLSVTAALALLVFFSVHWFGIraeglREYLKHYLSPSP--------FLLPFHLISEITRTLALAVRLFGNIM--S 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2190500896 292 LIIFSLIGLVfmmnvimgeaaawsttVISIGFTVFILLLKLLVAFIQAYVFTILSALFIGMAVEEH 357
Cdd:PRK13420  168 LELAALLVLL----------------VAGFLVPVPILMLHIIEALVQAYIFGMLALIYIAGGIQAH 217
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 201-357 1.88e-18

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 83.38  E-value: 1.88e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 201 FFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSDYYKELLTG--PPDAPVLIRIILVPIEIIGLVMRHLA 278
Cdd:MTH00173   79 FLFLISLNLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGlvPAGAPAGLNPFLVLIETVSILIRPLT 158

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2190500896 279 LAIRLFANMMGGSlIIFSLIGLVFMMNVIMGeaaAWSTTVISIGFTVFILLLKLLVAFIQAYVFTILSALFigmaVEEH 357
Cdd:MTH00173  159 LTVRLLANISAGH-IVLTLIGNYLSSSLFSS---SVVSLLLVLLIQVGYFIFEVAVMLIQAYIFTLLIKLY----SDEH 229
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 197-349 9.33e-18

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 81.53  E-value: 9.33e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 197 LLTAFFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSDYYKELLTG--PPDAPVLIRIILVPIEIIGLVM 274
Cdd:MTH00179   73 FLSLMLFLLTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHllPEGTPTPLIPMLVWIETISLLI 152

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2190500896 275 RHLALAIRLFANMMGGSLIIFSLIGLVFMMNVIMGeaaawstTVISIGFTVFILL--LKLLVAFIQAYVFTILSALF 349
Cdd:MTH00179  153 RPLALGVRLTANITAGHLLMHLISSAVFVLMNFMG-------MVALLTLLVLFLLtlLEVAVAMIQAYVFVLLLSLY 222
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 192-357 2.01e-17

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 80.82  E-value: 2.01e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 192 TFLPYLLTAFFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSDYYKELLT--GPPDAPVLIRIILVPIEI 269
Cdd:MTH00175   81 KYFPFILSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSilMPGGAPLVLAPFLVLIET 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 270 IGLVMRHLALAIRLFANMMGGSLIIFSLIGLVFmmNVIMGEAAAWSTTVISIgfTVFILLLKLLVAFIQAYVFTILSALF 349
Cdd:MTH00175  161 LSYLIRAISLGVRLAANISAGHLLFAILSGFAF--NMLSNGLIILSLFPMLI--MIFITLLEMAVAVIQAYVFCLLTTIY 236


                  ....*...
gi 2190500896 350 IGMAVEEH 357
Cdd:MTH00175  237 LGDTIALH 244
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 193-349 1.04e-16

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 78.54  E-value: 1.04e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 193 FLPYLLTAFFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSDYYKELLTG--PPDAPVLIRIILVPIEII 270
Cdd:MTH00176   71 SASIIISLFILVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHlvPQGTPPLLNPFLVLIELV 150

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2190500896 271 GLVMRHLALAIRLFANMMGGSLiifsLIGLVFMMNVIMGEAAAWSTTVISIgFTVFILLLKLLVAFIQAYVFTILSALF 349
Cdd:MTH00176  151 SLLIRPLTLAVRLAANLSAGHL----LLGLLGAAMWGLLPVSPLIGFLLLI-VQILYFMFEIAVCMIQAYVFTLLLSLY 224
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 193-351 1.71e-16

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 78.16  E-value: 1.71e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 193 FLPYLLTAFFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYG----SSDYYKELLtgPPDAPVLIRIILVPIE 268
Cdd:MTH00172   71 YFPFIISLFFFIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGfwrfKWDFFSILM--PSGAPLGLAPLLVLIE 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 269 IIGLVMRHLALAIRLFANMMGGSLIIFSLIGLVFMMNVIMGEAAAWSTTVIsigftVFILLLKLLVAFIQAYVFTILSAL 348
Cdd:MTH00172  149 TVSYISRAISLGVRLAANLSAGHLLFAILAGFGFNMLCASGFLSLFPLLIM-----VFITLLEIAVAVIQAYVFCLLTTI 223


                  ...
gi 2190500896 349 FIG 351
Cdd:MTH00172  224 YLA 226
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 195-346 3.94e-16

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 76.94  E-value: 3.94e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 195 PYLLTAFFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSDYYKELLTG--PPDAPVLIRIILVPIEIIGL 272
Cdd:MTH00035   74 GLLTTVFILILSINVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHlvPQGTPSFLIPLMVWIETLSL 153

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2190500896 273 VMRHLALAIRLFANMMGGSLIIFSLIGLVFMmnvimgeaAAWSTTVISIGFTVFILL--LKLLVAFIQAYVFTILS 346
Cdd:MTH00035  154 FAQPIALGLRLAANLTAGHLLIFLLSTAIWE--------LSNSPLISIITLIIFFLLfiLEIGVACIQAYVFTALV 221
atpI CHL00046
ATP synthase CF0 A subunit
 134-351 4.75e-15

ATP synthase CF0 A subunit


Pssm-ID: 176987  Cd Length: 228  Bit Score: 73.81  E-value: 4.75e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 134 LLAMLIVLGVFIALAQRYKKEHDRpeAPKGvFQNMMEVLVVFVRDeIAKPNIPDGKWRTFLPYLLTAFFFILVANILG-L 212
Cdd:CHL00046   26 LITSWVVIAILLGSALLATRNLQT--IPTG-GQNFFEYVLEFIRD-LAKTQIGEEEYRPWVPFIGTMFLFIFVSNWSGaL 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 213 VPFA---------GAATSNIAVTGVMAIMTfSIVLLY------GSSdYYKELLTGPPdapvliriILVPIEIIGLVMRHL 277
Cdd:CHL00046  102 LPWKlielphgelAAPTNDINTTVALALLT-SVAYFYaglskkGLG-YFGKYIQPTP--------ILLPINILEDFTKPL 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2190500896 278 ALAIRLFANMMGGSLIIFSLIGLVFMmnvimgeaaawsttVISIGftvfILLLKLLVAFIQAYVFTILSALFIG 351
Cdd:CHL00046  172 SLSFRLFGNILADELVVAVLVSLVPL--------------VVPIP----VMFLGLFTSGIQALIFATLAAAYIG 227
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 189-350 7.00e-15

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 73.45  E-value: 7.00e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 189 KWRTFLPYLLTAFFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSDYYKELLTG--PPDAPVLIRIILVP 266
Cdd:MTH00101   64 KGQTWSLMLMSLILFIGSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHflPQGTPTPLIPMLVI 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 267 IEIIGLVMRHLALAIRLFANMMGGSLIIfSLIG--LVFMMNVimgeaaawSTTVISIGFTVFILL--LKLLVAFIQAYVF 342
Cdd:MTH00101  144 IETISLFIQPMALAVRLTANITAGHLLI-HLIGgaTLALMSI--------STTTALITFIILILLtiLEFAVALIQAYVF 214


                  ....*...
gi 2190500896 343 TILSALFI 350
Cdd:MTH00101  215 TLLVSLYL 222
PRK13421 PRK13421
F0F1 ATP synthase subunit A; Provisional
 136-360 1.97e-14

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237383  Cd Length: 223  Bit Score: 72.04  E-value: 1.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 136 AMLIVLGVFIALAQRykkehdRPEAPKGVFQNMMEVLVVFVRDEIAKPNIPDGkwRTFLPYLLTAFFFILVANILGLVPF 215
Cdd:PRK13421   28 AIMAVLAAGSALATR------RLSLAPGRLQSVLELVVTTIDAQIRDTMQTDP--APYRALIGTLFLFVLVANWSSLVPG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 216 AGAATSNIAVTGVMAIMTFSIVLLYG--SSDYYKELLTGPPDAPVLIriilvPIEIIGLVMRHLALAIRLFANMMGGsli 293
Cdd:PRK13421  100 VEPPTAHLETDAALALIVFLATIYYGvrARGVRGYLATFAEPTWVMI-----PLNLVEQLTRTFSLIVRLFGNVMSG--- 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2190500896 294 ifsliglVFMMNVIMGEAaawsttvisiGFTVFILL--LKLLVAFIQAYVFTILSALFIGMAVEEHHPD 360
Cdd:PRK13421  172 -------VFVIGIVLSLA----------GLLVPIPLmaLDLLTGAVQAYIFAVLAMVFIGAAVSDDEAS 223
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 184-350 4.15e-13

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 68.07  E-value: 4.15e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 184 NIPDGKWRTFLPYLLTaffFILVANILGLVPFAGAATS----NIAVTGVMAIMTFSIVLLYGSSDYYKELLtgPPDAPVL 259
Cdd:MTH00073   63 NTPGHKWALILTSLMV---FLITMNLLGLLPYTFTPTTqlslNLGLAVPLWLATVLIGLRNQPTASLGHLL--PEGTPTL 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 260 IRIILVPIEIIGLVMRHLALAIRLFANMMGGSLIIFSLIGLVFMMNVIMgeaaawsTTVISIGFTVFILL--LKLLVAFI 337
Cdd:MTH00073  138 LIPILIIIETISLFIRPLALGVRLTANLTAGHLLIQLISTATLVLLPLM-------PTVSILTMIVLFLLtlLEIAVAMI 210

                         170
                  ....*....|...
gi 2190500896 338 QAYVFTILSALFI 350
Cdd:MTH00073  211 QAYVFVLLLSLYL 223
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 197-349 7.70e-12

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 64.46  E-value: 7.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 197 LLTAFFFILVANILGLVPFAGAATSNIAVTGVMAI----MTFSIVLLYGSSDYYKELLtgPPDAPVLIRIILVPIEIIGL 272
Cdd:MTH00120   73 LTSLMLLLLLINLLGLLPYTFTPTTQLSMNMALAIplwlATVLTGLRNQPTTSLAHLL--PEGTPTPLIPALILIETISL 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 273 VMRHLALAIRLFANMMGGSLII--FSLIGLVFMMNvimgeaaawSTTVISIGFTVFILL--LKLLVAFIQAYVFTILSAL 348
Cdd:MTH00120  151 LIRPLALGVRLTANLTAGHLLIqlISTATLNLLPT---------MPTLSLLTLIILLLLtiLELAVAMIQAYVFVLLLSL 221


                  .
gi 2190500896 349 F 349
Cdd:MTH00120  222 Y 222
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 193-349 8.41e-12

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 64.37  E-value: 8.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 193 FLPYLLTAFFFILVANILGLVPFAGAATSNIAVTGVMAI-MTFSIVL---LYGSSDYYKELLtgPPDAPVLIRIILVPIE 268
Cdd:MTH00005   73 FSSLISALFTMIILMNLSGLLPYVFSTSSHLIFTLTLGLpLWLSLIMssvTFSPKKFAAHLL--PGGAPDWLNPFLVLIE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 269 IIGLVMRHLALAIRLFANMMGGSlIIFSLIGLVfmmnvimgEAAAWSTTVIS----IGFTVFILLLKLLVAFIQAYVFTI 344
Cdd:MTH00005  151 TISILVRPITLSFRLAANMSAGH-IVLSLIGIY--------AASALFSSISStillILTQMGYILFEVGICLIQAYIFCL 221


                  ....*
gi 2190500896 345 LSALF 349
Cdd:MTH00005  222 LLSLY 226
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 184-349 2.25e-11

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 62.97  E-value: 2.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 184 NIPDGKWRTFLPYLLtafFFILVANILGLVPFAGAATSNIAVTGVMAI----MTFSIVLLYGSSDYYKELLtgPPDAPVL 259
Cdd:MTH00132   63 NVGGHKWALLLTSLM---LFLITLNMLGLLPYTFTPTTQLSLNMGLAVplwlATVIIGMRNQPTHALGHLL--PEGTPTP 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 260 IRIILVPIEIIGLVMRHLALAIRLFANMMGGSLIIFSLIGLVFMMNVIMGEAAAWSTTVIsigftvFIL-LLKLLVAFIQ 338
Cdd:MTH00132  138 LIPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLL------FLLtLLEVAVAMIQ 211

                         170
                  ....*....|.
gi 2190500896 339 AYVFTILSALF 349
Cdd:MTH00132  212 AYVFVLLLSLY 222
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 193-357 2.66e-09

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 57.26  E-value: 2.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 193 FLPYLLTAFFFILVANILGLVPFAGAATSNIAVTGVMAIMTFSIVLLYGSSDYYKELLT--GPPDAPVLIRIILVPIEII 270
Cdd:MTH00174   90 YLAFVLSLFILILFGNGLGLFPYVFTPTVHMVITLGLSFAIIVGTTLAGLITFRFNFFSilMPQGAPLALAPLLTIIETL 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 271 GLVMRHLALAIRLFANMMGGSL---IIFSLIGLVFMMNVIMGeaaawstTVISIGFTVFILLLKLLVAFIQAYVFTILSA 347
Cdd:MTH00174  170 SYISRAISLGVRLAANISSGHLlfsIIASFAWKMINTGILIG-------SFVPFAILIFVTILEMAVAIIQAYVFTLLTI 242

                         170
                  ....*....|
gi 2190500896 348 LFIGMAVEEH 357
Cdd:MTH00174  243 VYLRDTVELH 252
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 201-349 5.46e-08

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 52.67  E-value: 5.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 201 FFFILVANILGLVPFAGAATSNIAVTGVMAIMT--------------FSIVLLYGSSDYYKELltgppdapvliriILVP 266
Cdd:MTH00087   59 FIVLLLFCFGGLFPYSFSPCGMVEFTFLYALVAwlstflsflsksekFSVYLSKGSDSFLKTF-------------SMLF 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2190500896 267 IEIIGLVMRHLALAIRLFANMMGGSLIIFSLIglvfmmnvIMGEAAAWsttvisigFTVFILLLKLLVAFIQAYVFTILS 346
Cdd:MTH00087  126 VEIVSELSRPLALTLRLTVNLMVGHLISSLLN--------FLGEKYVW--------LSILAIMMECFVAFIQSYIFSRLI 189


                  ...
gi 2190500896 347 ALF 349
Cdd:MTH00087  190 YLY 192
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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