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MULTISPECIES: ATP-dependent DNA helicase [Anoxybacillus]
Protein Classification
ATP-dependent DNA helicase ( domain architecture ID 11439892 )
DNA helicase utilizes the energy from ATP hydrolysis to unwind double-stranded DNA, similar to XPD helicases, which play an important role in nucleotide excision repair pathway
List of domain hits
Name
Accession
Description
Interval
E-value
DinG
COG1199 Rad3-related DNA helicase DinG [Replication, recombination and repair];
27-618
1.20e-163
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain]
Cd Length: 629
Bit Score: 482.89
E-value: 1.20e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 27 YDI L PE A -- GFE L R DE Q IF MA FQLE RA FK E KKVMFA EAG V GTGKT IV YL LY A ICY AR YI GK PAI I AC A DET L I EQLV K K e 104
Cdd:COG1199 3 DGL L AL A fp GFE P R PG Q RE MA EAVA RA LA E GRHLLI EAG T GTGKT LA YL VP A LLA AR ET GK KVV I ST A TKA L Q EQLV E K - 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 105 g D IAKISRV L NINID V R L A K SPDQ YLCL NK L DDI L MTEEEELY E QI fdelps FVHDHAPLQTFYHY GDR KDYAH - LS DE Q 183
Cdd:COG1199 82 - D LPLLRKA L GLPLR V A L L K GRSN YLCL RR L EQA L QEGDDLDD E EL ------ LLARILAWASETWT GDR DELPL p ED DE L 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 184 W SKIAW D PFQ d CL A -- C EKRHR C GQT L S R DYY R K A t D LIICS H DFYMEHIWTY E arkregql P LLPE ASCV I F DE G H L L E 261
Cdd:COG1199 155 W RQVTS D ADN - CL G rr C PYYGV C PYE L A R RLA R E A - D VVVVN H HLLFADLALG E -------- E LLPE DDVL I I DE A H N L P 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 262 FA A QKALTYRMKETT L ET LL SR L LENDI R E --- Q L AY L I E DTL E LSARF F DE L MNHAK a VPGSNRQELTFTPS L SQLAQT 338
Cdd:COG1199 225 DR A RDMFSAELSSRS L LR LL RE L RKLGL R P glk K L LD L L E RLR E ALDDL F LA L EEEEE - LRLALGELPDEPEE L LEALDA 303
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 339 LR TKV E QIGDE L vfes E TYTIDHYQ L KVVD E Y L DQIHHS L YL F I --- HNRDAIT WLE SSLDGNT L VIM P RTVQEV LRE KV 415
Cdd:COG1199 304 LR DAL E ALAEA L ---- E EELERLAE L DALL E R L EELLFA L AR F L ria EDEGYVR WLE REGGDVR L HAA P LDPADL LRE LL 379
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 416 FS KRIPFIFS SATLS NEKS FDY M A KS LG I D - EYVSFHVD SPFDY DE Q MTI Y ---- M P IFENNERIF E KKYAYAI E KIRET 490
Cdd:COG1199 380 FS RARSVVLT SATLS VGGP FDY F A RR LG L D e DARTLSLP SPFDY EN Q ALL Y vprd L P RPSDRDGYL E AIAEAIA E LLEAS 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 491 N G RA LVLF PTREQ L NEFKARAQQEEGFTF L FE GD QEISE L VS RF QNEEET VL CA - QHL WEG L D I PG PS LS N VII WA LP Y P 569
Cdd:COG1199 460 G G NT LVLF TSYRA L EQVAELLRERLDIPV L VQ GD GSREA L LE RF REGGNS VL VG t GSF WEG V D L PG DA LS L VII VK LP F P 539
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 2191953110 570 - P N DPV FQ A K R KQTD ---- N P F WEVDV P YMILR L R QG V GRLIR QRD DRG I V CIF 618
Cdd:COG1199 540 p P D DPV LE A R R EALE argg N G F MYAYL P PAVIK L K QG A GRLIR SEE DRG V V VLL 593
Name
Accession
Description
Interval
E-value
DinG
COG1199 Rad3-related DNA helicase DinG [Replication, recombination and repair];
27-618
1.20e-163
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain]
Cd Length: 629
Bit Score: 482.89
E-value: 1.20e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 27 YDI L PE A -- GFE L R DE Q IF MA FQLE RA FK E KKVMFA EAG V GTGKT IV YL LY A ICY AR YI GK PAI I AC A DET L I EQLV K K e 104
Cdd:COG1199 3 DGL L AL A fp GFE P R PG Q RE MA EAVA RA LA E GRHLLI EAG T GTGKT LA YL VP A LLA AR ET GK KVV I ST A TKA L Q EQLV E K - 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 105 g D IAKISRV L NINID V R L A K SPDQ YLCL NK L DDI L MTEEEELY E QI fdelps FVHDHAPLQTFYHY GDR KDYAH - LS DE Q 183
Cdd:COG1199 82 - D LPLLRKA L GLPLR V A L L K GRSN YLCL RR L EQA L QEGDDLDD E EL ------ LLARILAWASETWT GDR DELPL p ED DE L 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 184 W SKIAW D PFQ d CL A -- C EKRHR C GQT L S R DYY R K A t D LIICS H DFYMEHIWTY E arkregql P LLPE ASCV I F DE G H L L E 261
Cdd:COG1199 155 W RQVTS D ADN - CL G rr C PYYGV C PYE L A R RLA R E A - D VVVVN H HLLFADLALG E -------- E LLPE DDVL I I DE A H N L P 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 262 FA A QKALTYRMKETT L ET LL SR L LENDI R E --- Q L AY L I E DTL E LSARF F DE L MNHAK a VPGSNRQELTFTPS L SQLAQT 338
Cdd:COG1199 225 DR A RDMFSAELSSRS L LR LL RE L RKLGL R P glk K L LD L L E RLR E ALDDL F LA L EEEEE - LRLALGELPDEPEE L LEALDA 303
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 339 LR TKV E QIGDE L vfes E TYTIDHYQ L KVVD E Y L DQIHHS L YL F I --- HNRDAIT WLE SSLDGNT L VIM P RTVQEV LRE KV 415
Cdd:COG1199 304 LR DAL E ALAEA L ---- E EELERLAE L DALL E R L EELLFA L AR F L ria EDEGYVR WLE REGGDVR L HAA P LDPADL LRE LL 379
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 416 FS KRIPFIFS SATLS NEKS FDY M A KS LG I D - EYVSFHVD SPFDY DE Q MTI Y ---- M P IFENNERIF E KKYAYAI E KIRET 490
Cdd:COG1199 380 FS RARSVVLT SATLS VGGP FDY F A RR LG L D e DARTLSLP SPFDY EN Q ALL Y vprd L P RPSDRDGYL E AIAEAIA E LLEAS 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 491 N G RA LVLF PTREQ L NEFKARAQQEEGFTF L FE GD QEISE L VS RF QNEEET VL CA - QHL WEG L D I PG PS LS N VII WA LP Y P 569
Cdd:COG1199 460 G G NT LVLF TSYRA L EQVAELLRERLDIPV L VQ GD GSREA L LE RF REGGNS VL VG t GSF WEG V D L PG DA LS L VII VK LP F P 539
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 2191953110 570 - P N DPV FQ A K R KQTD ---- N P F WEVDV P YMILR L R QG V GRLIR QRD DRG I V CIF 618
Cdd:COG1199 540 p P D DPV LE A R R EALE argg N G F MYAYL P PAVIK L K QG A GRLIR SEE DRG V V VLL 593
PRK08074
PRK08074 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
15-618
6.78e-65
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain]
Cd Length: 928
Bit Score: 230.22
E-value: 6.78e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 15 FD KLN E WIGDVFYDIL P ea GF E L R DE Q IF M AFQLER A FKEKKVMFA EAG V GTGK TIV YLL Y A ICY A RYIGK P AI I ACADE 94
Cdd:PRK08074 238 FD AFL E KTEEKLSLAM P -- KY E K R EG Q QE M MKEVYT A LRDSEHALI EAG T GTGK SLA YLL P A AYF A KKKEE P VV I STYTI 315
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 95 T L IE QL VK K eg DI AKISRVLNINIDVR L A K SPDQ YLCL N K LDDI L m T EE EEL Y E ------ Q IFDE L psfvhdhap LQ T fy 168
Cdd:PRK08074 316 Q L QQ QL LE K -- DI PLLQKIFPFPVEAA L L K GRSH YLCL R K FEQA L - Q EE DDN Y D valtka Q LLVW L --------- TE T -- 381
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 169 HY GD R kdyahls DE Q --------- W SK IA W D PFQ D C lac E K RHR cgq TL SR DY Y RK A ------ T DL I I CS H DFYM e HIW T 233
Cdd:PRK08074 382 ET GD L ------- DE L nlpsggkll W NR IA S D GES D G --- G K QSP --- WF SR CF Y QR A knrakf A DL V I TN H ALLL - TDL T 447
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 234 Y E A rkregql PLLP EASCV I F DE G H LL E F AA QKA L TYRMKETTLET LLSRL --- L E NDIREQ LA Y L IEDTLEL S ARF F DE 310
Cdd:PRK08074 448 S E E ------- PLLP SYEHI I I DE A H HF E E AA SRH L GEQFSYMSFQL LLSRL gtl E E DGLLSK LA K L FKKSDQA S RSS F RD 520
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 311 L --------------------- MNHA K AVPGSN R ------------------ Q EL T -- FTPS L SQ L AQT L RTKVEQIGDE 349
Cdd:PRK08074 521 L deslkelkfeadelfqmlrsf VLKR K KQEQNG R liyryntesekgklwdai T EL A nr LCYD L RD L LTL L EAQKKELQEK 600
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 350 LVF ES ETY T IDHYQ L KVVD E YLD Q IHH sl Y LF IHNR D AI TW L E SSLD G N ---- T L VIM P RT V Q E V L REKV F S K RIPF I FS 425
Cdd:PRK08074 601 MES ES AFL T GEYAH L IDLL E KMA Q LLQ -- L LF EEDP D YV TW I E IDAK G A inat R L YAQ P VE V A E R L ADEF F A K KKSV I LT 678
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 426 SATL SNEK SFDY MAKS LG I - D E Y V - SFHVD SPF D Y D EQ MTIYM P ----- I FENNERIFEKKY A YA I E KI - RE T N GR A LVL 497
Cdd:PRK08074 679 SATL TVNG SFDY IIER LG L e D F Y P r TLQIP SPF S Y E EQ AKLMI P tdmpp I KDVPIEEYIEEV A AY I A KI a KA T K GR M LVL 758
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 498 F PTR E Q L NEFKARAQQ E --- EG FTF L FE G DQEI S -- E L VSR FQ NEEETV L CA - QHL WEG L DIPG PS LS NVI I WA LP Y - PP 570
Cdd:PRK08074 759 F TSY E M L KKTYYNLKN E eel EG YVL L AQ G VSSG S ra R L TKQ FQ QFDKAI L LG t SSF WEG I DIPG DE LS CLV I VR LP F a PP 838
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 2191953110 571 ND PV FQ AK ---- RK Q TD NPF W E VDV P YMI LR LR QG V GRLIR QRD DRG I V CIF 618
Cdd:PRK08074 839 DQ PV ME AK sewa KE Q GE NPF Q E LSL P QAV LR FK QG F GRLIR TET DRG T V FVL 890
Helicase_C_2
pfam13307 Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
487-618
3.15e-34
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain]
Cd Length: 168
Bit Score: 128.06
E-value: 3.15e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 487 IRETN G RA LV L FP TREQ L NEFKA R AQQ --- E E G FTFLFE - G DQEISE L VSR F QNEEET - VL CA --- QHLW EG L D I PG PS L 558
Cdd:pfam13307 4 LKVIP G GV LV F FP SYSY L EKVAE R LKE sgl E K G IEIFVQ p G EGSREK L LEE F KKKGKG a VL FG vcg GSFS EG I D F PG DL L 83
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2191953110 559 SN VII WA LP Y P - P N DPV FQ AKR ---- KQTD NPF W E VDV P YMILRLR Q GV GRLIR QRD D R G IVCIF 618
Cdd:pfam13307 84 RA VII VG LP F P n P D DPV VE AKR eyld SKGG NPF N E WYL P QAVRAVN Q AI GRLIR HEN D Y G AIVLL 148
HELICc2
smart00491 helicase superfamily c-terminal domain;
547-617
8.59e-13
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain]
Cd Length: 142
Bit Score: 66.15
E-value: 8.59e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2191953110 547 LW EG L D I P GPSLSN VII WAL P Y P - P ND P VFQ A KRKQT D ----- N PF W EV DVPYMILR L R Q GV GR L IR QRD D R G I V CI 617
Cdd:smart00491 59 VS EG I D F P DDLGRA VII VGI P F P n P DS P ILR A RLEYL D ekggi R PF D EV YLFDAMRA L A Q AI GR A IR HKN D Y G V V VL 135
Csf4_U
cd09708 CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly ...
503-610
1.81e-05
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DinG family DNA helicase
Pssm-ID: 187839 [Multi-domain]
Cd Length: 632
Bit Score: 47.66
E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 503 QL N E FKAR A Q --- Q E E GFTF lfe GDQ E ISE L VSRFQNEEETVLC A QHL W E G L D IPG PS -------- L SNV II WAL P YPP N 571
Cdd:cd09708 505 QL V E LGIP A E ivi Q S E KNRL --- ASA E QQF L ALYANGIQPVLIA A GGA W T G I D LHD PS vspdkdnl L TDL II TCA P FGL N 581
90 100 110
....*....|....*....|....*....|....*....
gi 2191953110 572 DPVFQA KR KQTDNPFW E V d VPYMILR LRQG V GRL I R QR D 610
Cdd:cd09708 582 RSLSML KR IRKTSVRP E I - INESLMM LRQG L GRL V R HP D 619
Name
Accession
Description
Interval
E-value
DinG
COG1199 Rad3-related DNA helicase DinG [Replication, recombination and repair];
27-618
1.20e-163
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain]
Cd Length: 629
Bit Score: 482.89
E-value: 1.20e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 27 YDI L PE A -- GFE L R DE Q IF MA FQLE RA FK E KKVMFA EAG V GTGKT IV YL LY A ICY AR YI GK PAI I AC A DET L I EQLV K K e 104
Cdd:COG1199 3 DGL L AL A fp GFE P R PG Q RE MA EAVA RA LA E GRHLLI EAG T GTGKT LA YL VP A LLA AR ET GK KVV I ST A TKA L Q EQLV E K - 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 105 g D IAKISRV L NINID V R L A K SPDQ YLCL NK L DDI L MTEEEELY E QI fdelps FVHDHAPLQTFYHY GDR KDYAH - LS DE Q 183
Cdd:COG1199 82 - D LPLLRKA L GLPLR V A L L K GRSN YLCL RR L EQA L QEGDDLDD E EL ------ LLARILAWASETWT GDR DELPL p ED DE L 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 184 W SKIAW D PFQ d CL A -- C EKRHR C GQT L S R DYY R K A t D LIICS H DFYMEHIWTY E arkregql P LLPE ASCV I F DE G H L L E 261
Cdd:COG1199 155 W RQVTS D ADN - CL G rr C PYYGV C PYE L A R RLA R E A - D VVVVN H HLLFADLALG E -------- E LLPE DDVL I I DE A H N L P 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 262 FA A QKALTYRMKETT L ET LL SR L LENDI R E --- Q L AY L I E DTL E LSARF F DE L MNHAK a VPGSNRQELTFTPS L SQLAQT 338
Cdd:COG1199 225 DR A RDMFSAELSSRS L LR LL RE L RKLGL R P glk K L LD L L E RLR E ALDDL F LA L EEEEE - LRLALGELPDEPEE L LEALDA 303
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 339 LR TKV E QIGDE L vfes E TYTIDHYQ L KVVD E Y L DQIHHS L YL F I --- HNRDAIT WLE SSLDGNT L VIM P RTVQEV LRE KV 415
Cdd:COG1199 304 LR DAL E ALAEA L ---- E EELERLAE L DALL E R L EELLFA L AR F L ria EDEGYVR WLE REGGDVR L HAA P LDPADL LRE LL 379
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 416 FS KRIPFIFS SATLS NEKS FDY M A KS LG I D - EYVSFHVD SPFDY DE Q MTI Y ---- M P IFENNERIF E KKYAYAI E KIRET 490
Cdd:COG1199 380 FS RARSVVLT SATLS VGGP FDY F A RR LG L D e DARTLSLP SPFDY EN Q ALL Y vprd L P RPSDRDGYL E AIAEAIA E LLEAS 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 491 N G RA LVLF PTREQ L NEFKARAQQEEGFTF L FE GD QEISE L VS RF QNEEET VL CA - QHL WEG L D I PG PS LS N VII WA LP Y P 569
Cdd:COG1199 460 G G NT LVLF TSYRA L EQVAELLRERLDIPV L VQ GD GSREA L LE RF REGGNS VL VG t GSF WEG V D L PG DA LS L VII VK LP F P 539
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 2191953110 570 - P N DPV FQ A K R KQTD ---- N P F WEVDV P YMILR L R QG V GRLIR QRD DRG I V CIF 618
Cdd:COG1199 540 p P D DPV LE A R R EALE argg N G F MYAYL P PAVIK L K QG A GRLIR SEE DRG V V VLL 593
PRK08074
PRK08074 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
15-618
6.78e-65
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain]
Cd Length: 928
Bit Score: 230.22
E-value: 6.78e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 15 FD KLN E WIGDVFYDIL P ea GF E L R DE Q IF M AFQLER A FKEKKVMFA EAG V GTGK TIV YLL Y A ICY A RYIGK P AI I ACADE 94
Cdd:PRK08074 238 FD AFL E KTEEKLSLAM P -- KY E K R EG Q QE M MKEVYT A LRDSEHALI EAG T GTGK SLA YLL P A AYF A KKKEE P VV I STYTI 315
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 95 T L IE QL VK K eg DI AKISRVLNINIDVR L A K SPDQ YLCL N K LDDI L m T EE EEL Y E ------ Q IFDE L psfvhdhap LQ T fy 168
Cdd:PRK08074 316 Q L QQ QL LE K -- DI PLLQKIFPFPVEAA L L K GRSH YLCL R K FEQA L - Q EE DDN Y D valtka Q LLVW L --------- TE T -- 381
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 169 HY GD R kdyahls DE Q --------- W SK IA W D PFQ D C lac E K RHR cgq TL SR DY Y RK A ------ T DL I I CS H DFYM e HIW T 233
Cdd:PRK08074 382 ET GD L ------- DE L nlpsggkll W NR IA S D GES D G --- G K QSP --- WF SR CF Y QR A knrakf A DL V I TN H ALLL - TDL T 447
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 234 Y E A rkregql PLLP EASCV I F DE G H LL E F AA QKA L TYRMKETTLET LLSRL --- L E NDIREQ LA Y L IEDTLEL S ARF F DE 310
Cdd:PRK08074 448 S E E ------- PLLP SYEHI I I DE A H HF E E AA SRH L GEQFSYMSFQL LLSRL gtl E E DGLLSK LA K L FKKSDQA S RSS F RD 520
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 311 L --------------------- MNHA K AVPGSN R ------------------ Q EL T -- FTPS L SQ L AQT L RTKVEQIGDE 349
Cdd:PRK08074 521 L deslkelkfeadelfqmlrsf VLKR K KQEQNG R liyryntesekgklwdai T EL A nr LCYD L RD L LTL L EAQKKELQEK 600
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 350 LVF ES ETY T IDHYQ L KVVD E YLD Q IHH sl Y LF IHNR D AI TW L E SSLD G N ---- T L VIM P RT V Q E V L REKV F S K RIPF I FS 425
Cdd:PRK08074 601 MES ES AFL T GEYAH L IDLL E KMA Q LLQ -- L LF EEDP D YV TW I E IDAK G A inat R L YAQ P VE V A E R L ADEF F A K KKSV I LT 678
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 426 SATL SNEK SFDY MAKS LG I - D E Y V - SFHVD SPF D Y D EQ MTIYM P ----- I FENNERIFEKKY A YA I E KI - RE T N GR A LVL 497
Cdd:PRK08074 679 SATL TVNG SFDY IIER LG L e D F Y P r TLQIP SPF S Y E EQ AKLMI P tdmpp I KDVPIEEYIEEV A AY I A KI a KA T K GR M LVL 758
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 498 F PTR E Q L NEFKARAQQ E --- EG FTF L FE G DQEI S -- E L VSR FQ NEEETV L CA - QHL WEG L DIPG PS LS NVI I WA LP Y - PP 570
Cdd:PRK08074 759 F TSY E M L KKTYYNLKN E eel EG YVL L AQ G VSSG S ra R L TKQ FQ QFDKAI L LG t SSF WEG I DIPG DE LS CLV I VR LP F a PP 838
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 2191953110 571 ND PV FQ AK ---- RK Q TD NPF W E VDV P YMI LR LR QG V GRLIR QRD DRG I V CIF 618
Cdd:PRK08074 839 DQ PV ME AK sewa KE Q GE NPF Q E LSL P QAV LR FK QG F GRLIR TET DRG T V FVL 890
dinG
PRK11747 ATP-dependent DNA helicase DinG; Provisional
27-618
7.57e-50
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain]
Cd Length: 697
Bit Score: 184.65
E-value: 7.57e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 27 Y DI L P E A -- GF EL R DE Q IF M AFQLERAF ----- K EKKVMFA EAG V G T GKT IV YLL YA I CY AR YIG K PAI I AC A DET L I EQ 99
Cdd:PRK11747 14 Y KA L Q E Q lp GF IP R AG Q RQ M IAEVAKTL ageyl K DGRILVI EAG T G V GKT LS YLL AG I PI AR AEK K KLV I ST A TVA L Q EQ 93
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 100 LV K K eg D IAKISRVLNINIDVR LAK SPDQ Y L C LN KL DDILMT E EEELYEQI F DELPSFVH D HAPLQTF ------ YHY --- 170
Cdd:PRK11747 94 LV S K -- D LPLLLKISGLDFKFT LAK GRGR Y V C PR KL AALASD E GTQQDLLL F LDDELTPP D EEEQKLL arlaka LAT gkw 171
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 171 - GDR KDYAH - LS D EQ W SK I AW D PFQ d CL A -- C EKRHR C GQTLS R DYYRK A t D LIICS HD FYM ehiwtye A RKRE G QLPL L 246
Cdd:PRK11747 172 d GDR DHWPE p ID D SL W QR I TT D KHS - CL G rn C PYFRE C PFFKA R REIDE A - D VVVAN HD LVL ------- A DLEL G GGVV L 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 247 P EAS - CV - IF DEGH L L ------ E FAA Q ka LTYRMKETT LE T LL SR L LE ---------------- N DIR E Q L AY L IEDTLE 302
Cdd:PRK11747 243 P DPE n LL y VL DEGH H L pdvard H FAA S -- AELKGTADW LE K LL KL L TK lvalimepplalperl N AHC E E L RE L LASLNQ 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 303 LSAR F F ----------------- D EL MNH A KA vpgsnrqeltftps L SQ L AQT L RTKV E QIGDE L VFESE T YT ID HYQ L K 365
Cdd:PRK11747 321 ILNL F L paggeearyrfemgelp E EL LEL A ER -------------- L AK L TEK L LGLL E KLLND L SEAMK T GK ID IVR L E 386
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 366 ------- VVDEY L DQIHH -- S L YLFIHNRDAI --- T W LESSLDGNTLVIM ---- P RT V QEV L REKVF S KRIPFIFS SATL 429
Cdd:PRK11747 387 rlllelg RALGR L EALSK lw R L AAKEDQESGA pma R W ITREERDGQGDYL fhas P IR V GDQ L ERLLW S RAPGAVLT SATL 466
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 430 SNEK SFD YMAKSL G ID E ----- YVS fh VD SPFDY DE Q MTIYM P IFENNERIF E KKY A YAI E KIR --- E TNGRA LVLF PT R 501
Cdd:PRK11747 467 RSLN SFD RFQEQS G LP E kdgdr FLA -- LP SPFDY PN Q GKLVI P KMRAEPDNE E AHT A EMA E FLP ell E KHKGS LVLF AS R 544
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 502 E Q LNEFKARAQQEEGFTF L FE GDQ EISE L V ---- S R FQNE E ET VL CA - Q HLW EGLD I PG PS L SN VII WAL P Y - P P ND PV F 575
Cdd:PRK11747 545 R Q MQKVADLLPRDLRLML L VQ GDQ PRQR L L ekhk K R VDEG E GS VL FG l Q SFA EGLD L PG DY L TQ VII TKI P F a V P DS PV E 624
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 2191953110 576 QAK ---- RKQTD NPF W E VD VP YMILR L R Q G VGRLIR QRD DRG I V C I F 618
Cdd:PRK11747 625 ATL aewl KSRGG NPF M E IS VP DASFK L I Q A VGRLIR SEQ DRG R V T I L 671
Helicase_C_2
pfam13307 Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
487-618
3.15e-34
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain]
Cd Length: 168
Bit Score: 128.06
E-value: 3.15e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 487 IRETN G RA LV L FP TREQ L NEFKA R AQQ --- E E G FTFLFE - G DQEISE L VSR F QNEEET - VL CA --- QHLW EG L D I PG PS L 558
Cdd:pfam13307 4 LKVIP G GV LV F FP SYSY L EKVAE R LKE sgl E K G IEIFVQ p G EGSREK L LEE F KKKGKG a VL FG vcg GSFS EG I D F PG DL L 83
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2191953110 559 SN VII WA LP Y P - P N DPV FQ AKR ---- KQTD NPF W E VDV P YMILRLR Q GV GRLIR QRD D R G IVCIF 618
Cdd:pfam13307 84 RA VII VG LP F P n P D DPV VE AKR eyld SKGG NPF N E WYL P QAVRAVN Q AI GRLIR HEN D Y G AIVLL 148
HELICc2
smart00491 helicase superfamily c-terminal domain;
547-617
8.59e-13
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain]
Cd Length: 142
Bit Score: 66.15
E-value: 8.59e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2191953110 547 LW EG L D I P GPSLSN VII WAL P Y P - P ND P VFQ A KRKQT D ----- N PF W EV DVPYMILR L R Q GV GR L IR QRD D R G I V CI 617
Cdd:smart00491 59 VS EG I D F P DDLGRA VII VGI P F P n P DS P ILR A RLEYL D ekggi R PF D EV YLFDAMRA L A Q AI GR A IR HKN D Y G V V VL 135
PRK07246
PRK07246 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
34-617
5.00e-11
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 180905 [Multi-domain]
Cd Length: 820
Bit Score: 65.86
E-value: 5.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 34 G F E L R DE Q IFM A FQLERA F KEKKVM F A EA GV G T GKT IV YLL YAI cy A RYIGKPA I IACADET L IE Q LVKK E gd IAK I SR V 113
Cdd:PRK07246 243 G L E E R PK Q ESF A KLVGED F HDGPAS F I EA QT G I GKT YG YLL PLL -- A QSDQRQI I VSVPTKI L QD Q IMAE E -- VKA I QE V 318
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 114 LN I NI dv RLA K S P DQ YL ------- C L NKL DD -------------- ILM TE EEE L -------- Y EQI FD E L P sfv HD HAPL 164
Cdd:PRK07246 319 FH I DC -- HSL K G P QN YL kldafyd S L QQN DD nrlvnrykmqllvw LTE TE TGD L deikqkqr Y AAY FD Q L K --- HD GNLS 393
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 165 Q T -- FY H Y gdrk D Y ahlsdeq W SK iawdpfqdcl AC EK RHRC gqtlsrdyyrkat D L I I CS H DFYMEHIWTYEARK R e GQ 242
Cdd:PRK07246 394 Q S sl FY D Y ---- D F ------- W KR ---------- SY EK AKTA ------------- R L L I TN H AYFLTRVQDDKDFA R - NK 438
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 243 L pllpeasc VI FDE GHL L EFAAQKALTYRMKE T TLETLLSRL L ENDIR eqlay L IEDT L EL S AR F fd EL m NHAKAVPGSN 322
Cdd:PRK07246 439 V -------- LV FDE AQK L MLQLEQLSRHQLNI T SFLQTIQKA L SGPLP ----- L LQKR L LE S IS F -- EL - LQLSEQFYQG 502
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 323 RQELTFTP SLS Q L A Q TLRT - K V EQIGDELV F ESETYT id H Y Q L KV v DEYLDQ ihhslylfihnrd AI T W L E S SLDGN T LV 401
Cdd:PRK07246 503 KERQLIHD SLS R L H Q YFSE l E V AGFQELQA F FATAEG -- D Y W L ES - EKQSEK ------------- RV T Y L N S ASKAF T HF 566
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 402 -- IM P R T VQE vlrekvfskripf I F S SATL SNEKSF d YM A KS LG ID EY v S FH VDSPFDYDE Q MTIYMPIFENNERIFEKK 479
Cdd:PRK07246 567 sq LL P E T CKT ------------- Y F V SATL QISPRV - SL A DL LG FE EY - L FH KIEKDKKQD Q LVVVDQDMPLVTETSDEV 631
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 480 YA YA I ---- E KIRETNGRA LVLF PTREQ L --------- NEFKAR AQ QEE G FTF lfegdqeis ELVS RF QNE E ETV L C - AQ 545
Cdd:PRK07246 632 YA EE I akrl E ELKQLQQPI LVLF NSKKH L lavsdlldq WQVSHL AQ EKN G TAY --------- NIKK RF DRG E QQI L L g LG 702
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2191953110 546 HL WEG L D - IPGPSLSN VI I w A LP YP - P N DP VFQAK ---- RKQTD NPF WEVDV P YM ILRL R Q GV GR LI R QR D DRGI V C I 617
Cdd:PRK07246 703 SF WEG V D f VQADRMIE VI T - R LP FD n P E DP FVKKM nqyl LQEGK NPF YDYFL P MT ILRL K Q AI GR TM R RE D QKSA V L I 779
Csf4_U
cd09708 CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly ...
503-610
1.81e-05
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DinG family DNA helicase
Pssm-ID: 187839 [Multi-domain]
Cd Length: 632
Bit Score: 47.66
E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 503 QL N E FKAR A Q --- Q E E GFTF lfe GDQ E ISE L VSRFQNEEETVLC A QHL W E G L D IPG PS -------- L SNV II WAL P YPP N 571
Cdd:cd09708 505 QL V E LGIP A E ivi Q S E KNRL --- ASA E QQF L ALYANGIQPVLIA A GGA W T G I D LHD PS vspdkdnl L TDL II TCA P FGL N 581
90 100 110
....*....|....*....|....*....|....*....
gi 2191953110 572 DPVFQA KR KQTDNPFW E V d VPYMILR LRQG V GRL I R QR D 610
Cdd:cd09708 582 RSLSML KR IRKTSVRP E I - INESLMM LRQG L GRL V R HP D 619
DEXDc
smart00487 DEAD-like helicases superfamily;
34-154
2.27e-05
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain]
Cd Length: 201
Bit Score: 45.95
E-value: 2.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2191953110 34 GFE LR DE Q IFM afq L E RAFKEKKVMFAE A GV G T GKT IVY LL Y A ICYA - R YI G KPAIIACADET L I EQ LVKKEGDIAKISR 112
Cdd:smart00487 6 FEP LR PY Q KEA --- I E ALLSGLRDVILA A PT G S GKT LAA LL P A LEAL k R GK G GRVLVLVPTRE L A EQ WAEELKKLGPSLG 82
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2191953110 113 VLNINIDVRLA K SPDQYLCLNKLD DIL - M T eeeel YEQIF D E L 154
Cdd:smart00487 83 LKVVGLYGGDS K REQLRKLESGKT DIL v T T ----- PGRLL D L L 120
SF2_C_XPD
cd18788 C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ...
549-618
2.78e-05
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain]
Cd Length: 159
Bit Score: 44.90
E-value: 2.78e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2191953110 549 EG L D IPGPSLSN VI IWAL PYP P - N DP VFQA K RKQTDNPF ------ W E VDVPYMIL R - LR Q GV GR L IR QRD D R G IVCIF 618
Cdd:cd18788 78 EG I D FSDDLGRA VI MVGI PYP N t K DP ILKL K MDDLEYLR dkgllt G E DWYTFQAM R a VN Q AI GR A IR HKN D Y G AIVLL 155
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
