|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15057 |
PRK15057 |
UDP-glucose 6-dehydrogenase; Provisional |
1-388 |
0e+00 |
|
UDP-glucose 6-dehydrogenase; Provisional
Pssm-ID: 185017 [Multi-domain] Cd Length: 388 Bit Score: 744.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNQKKSPIVDKEIQDYLSNKSLNFRATTDKEDAYREADFVIIA 80
Cdd:PRK15057 1 MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 81 TPTDYDPKTNYFNTSTVEAVIKDVIAINPNAVMIIKSTIPVGFTKSIKEELGIDNVFFSPEFLREGRALYDNLHPSRIVI 160
Cdd:PRK15057 81 TPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 161 GERSERAERFAALLQEGAIKKDIPVLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEGVCLDPRIGN 240
Cdd:PRK15057 161 GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEGVCLDPRIGN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 241 HYNNPSFGYGGYCLPKDTKQLLANYQAVPNNLISAIVDANRTRKDFISDSILARQPKVVGVYRLIMKSGSDNFRASSIQG 320
Cdd:PRK15057 241 HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQG 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2193613060 321 IMKRIKAKGVQVIIYEPAMQEDEFFHSRVVRDLDAFKKEADVIISNRMAEELADVADKVYTRDLFGSD 388
Cdd:PRK15057 321 IMKRIKAKGVEVIIYEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD 388
|
|
| NDP-sugDHase |
TIGR03026 |
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ... |
1-378 |
7.17e-125 |
|
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.
Pssm-ID: 274399 [Multi-domain] Cd Length: 409 Bit Score: 366.17 E-value: 7.17e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIA-QNHEVVALDIVQAKVDMLNQKKSPIVDKEIQDYLSN--KSLNFRATTDKEDAYREADFV 77
Cdd:TIGR03026 1 MKIAVIGLGYVGLPLAALLAdLGHDVTGVDIDQEKVDKLNKGKSPIYEPGLDELLAKalKAGRLRATTDYEEAIRDADVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 78 IIATPTDYDPkTNYFNTSTVEAVIKDVIA-INPNAVMIIKSTIPVGFT----KSIKEELGID-----NVFFSPEFLREGR 147
Cdd:TIGR03026 81 IICVPTPLKE-DGSPDLSYVESAAETIAKhLRKGATVVLESTVPPGTTeevvKPILERSGLKlgedfYLAYNPEFLREGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 148 ALYDNLHPSRIVIGERSERAERFAALLQEGAikkDIPVLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQ 227
Cdd:TIGR03026 160 AVHDLLHPDRIVGGETEEAGEAVAELYSPII---DGPVLVTSIETAEMIKLAENTFRAVKIAFANELARICEALGIDVYE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 228 IIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQA--VPNNLISAIVDANRTRKDFISDSILAR----QPKVVGV 301
Cdd:TIGR03026 237 VIEAAGTDPRIGFNFLNPGPGVGGHCIPKDPLALIAKAKElgYNPELIEAAREINDSQPDYVVEKIKDLlgplKGKTVLI 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2193613060 302 YRLIMKSGSDNFRASSIQGIMKRIKAKGVQVIIYEPAMQEDEFFHSRVVRDLDAFKKEADVIISNRMAEELADVADK 378
Cdd:TIGR03026 317 LGLAFKPNTDDVRESPALDIIELLKEKGAKVKAYDPLVPEEEVKGLPSIDDLEEALKGADALVILTDHSEFKDLDLE 393
|
|
| Ugd |
COG1004 |
UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis]; |
1-341 |
6.33e-76 |
|
UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440628 [Multi-domain] Cd Length: 436 Bit Score: 241.46 E-value: 6.33e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIAQ-NHEVVALDIVQAKVDMLNQKKSPI----VDKEIQDYLSNKSLNFraTTDKEDAYREAD 75
Cdd:COG1004 1 MKIAVIGTGYVGLVTAACLAElGHEVTCVDIDEEKIEALNAGEIPIyepgLEELVARNVAAGRLRF--TTDLAEAVAEAD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 76 FVIIA--TPTDYDpktNYFNTSTVEAVIKDVI-AINPNAVMIIKSTIPVGFTKSIK----EELGIDNVFFS----PEFLR 144
Cdd:COG1004 79 VVFIAvgTPSDED---GSADLSYVLAAARSIGeALKGYKVVVTKSTVPVGTADRVRaiiaEELRGAGVDFDvvsnPEFLR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 145 EGRALYDNLHPSRIVIGERSERAERFAALLQEGAIKKDIPVLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLN 224
Cdd:COG1004 156 EGSAVEDFLRPDRIVIGVDSERAAEVLRELYAPFVRNGTPIIVTDLRSAELIKYAANAFLATKISFINEIANLCEKVGAD 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 225 TRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQL--LANYQAVPNNLISAIVDANRTRKDFISDSILAR-----QPK 297
Cdd:COG1004 236 VEEVARGIGLDSRIGPKFLYAGIGYGGSCFPKDVRALiaTARELGYDLRLLEAVEEVNERQKRRLVEKIREHlggdlKGK 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 2193613060 298 VVGVYRLIMKSGSDNFR-ASSIQgIMKRIKAKGVQVIIYEP-AMQE 341
Cdd:COG1004 316 TIAVLGLAFKPNTDDMReSPALD-IIEALLEAGARVRAYDPvAMEN 360
|
|
| UDPG_MGDP_dh_N |
pfam03721 |
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose ... |
1-176 |
5.69e-38 |
|
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.
Pssm-ID: 397677 [Multi-domain] Cd Length: 186 Bit Score: 135.07 E-value: 5.69e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIAQ-NHEVVALDIVQAKVDMLNQKKSPIVDKEIQDYL-SNKSLNFRATTDKEDAYREADFVI 78
Cdd:pfam03721 1 MKISVIGLGYVGLPTAACLAEiGHDVIGVDIDEEKVDKLNSGQIPIYEPGLDELVkANVSGRLSFTTDYSTAIEEADVIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 79 IATPTDYDPKTNYFNTSTVEAVIKDVI-AINPNAVMIIKSTIPVGFT----KSIKEEL----GID-NVFFSPEFLREGRA 148
Cdd:pfam03721 81 IAVGTPSKKGGGAADLKYVESAARSIApHLKKGKVVVVKSTVPVGTTenlvKPIIEEGgkkvGVDfDVASNPEFLREGSA 160
|
170 180
....*....|....*....|....*...
gi 2193613060 149 LYDNLHPSRIVIGERSERAErfaALLQE 176
Cdd:pfam03721 161 VYDLFNPDRVVIGVTEKCAE---AALEE 185
|
|
| UDPG_MGDP_dh_C |
smart00984 |
UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes ... |
300-385 |
1.06e-17 |
|
UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.
Pssm-ID: 214954 [Multi-domain] Cd Length: 99 Bit Score: 77.55 E-value: 1.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 300 GVYRLIMKSGSDNFRASSIQGIMKRIKAKGVQVIIYEP-AMQE-DEFFHSRVVRDLDAFKKEADVIISNRMAE------- 370
Cdd:smart00984 1 AVLGLAFKPNTDDLRESPALDIIEELLEAGAEVVVYDPyAMEEaREYGLTYVSDLEEALKGADAVVIATEHDEfrsldpe 80
|
90
....*....|....*...
gi 2193613060 371 ELADVADK---VYTRDLF 385
Cdd:smart00984 81 ELKDLMKKpvvVDGRNIL 98
|
|
| LDH_MDH_like |
cd00650 |
NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Members ... |
4-122 |
1.59e-03 |
|
NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Members of this family include ubiquitous enzymes like L-lactate dehydrogenases (LDH), L-2-hydroxyisocaproate dehydrogenases, and some malate dehydrogenases (MDH). LDH catalyzes the last step of glycolysis in which pyruvate is converted to L-lactate. MDH is one of the key enzymes in the citric acid cycle, facilitating both the conversion of malate to oxaloacetate and replenishing levels of oxalacetate by reductive carboxylation of pyruvate. The LDH/MDH-like proteins are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.
Pssm-ID: 133419 [Multi-domain] Cd Length: 263 Bit Score: 40.00 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 4 TISGTGYVG--LSNGILIAQNH---EVVALDIVQAKVDmlnqkkspIVDKEIQDYLSNKSL-NFRATTDKEDAYREADFV 77
Cdd:cd00650 3 VIGAGGNVGpaLAFGLADGSVLlaiELVLYDIDEEKLK--------GVAMDLQDAVEPLADiKVSITDDPYEAFKDADVV 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2193613060 78 IIAT-----PTDYDPKTNYFNTSTVEAVIKDVIAINPNAVMIIKSTiPVG 122
Cdd:cd00650 75 IITAgvgrkPGMGRLDLLKRNVPIVKEIGDNIEKYSPDAWIIVVSN-PVD 123
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15057 |
PRK15057 |
UDP-glucose 6-dehydrogenase; Provisional |
1-388 |
0e+00 |
|
UDP-glucose 6-dehydrogenase; Provisional
Pssm-ID: 185017 [Multi-domain] Cd Length: 388 Bit Score: 744.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNQKKSPIVDKEIQDYLSNKSLNFRATTDKEDAYREADFVIIA 80
Cdd:PRK15057 1 MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 81 TPTDYDPKTNYFNTSTVEAVIKDVIAINPNAVMIIKSTIPVGFTKSIKEELGIDNVFFSPEFLREGRALYDNLHPSRIVI 160
Cdd:PRK15057 81 TPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 161 GERSERAERFAALLQEGAIKKDIPVLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEGVCLDPRIGN 240
Cdd:PRK15057 161 GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEGVCLDPRIGN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 241 HYNNPSFGYGGYCLPKDTKQLLANYQAVPNNLISAIVDANRTRKDFISDSILARQPKVVGVYRLIMKSGSDNFRASSIQG 320
Cdd:PRK15057 241 HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQG 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2193613060 321 IMKRIKAKGVQVIIYEPAMQEDEFFHSRVVRDLDAFKKEADVIISNRMAEELADVADKVYTRDLFGSD 388
Cdd:PRK15057 321 IMKRIKAKGVEVIIYEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD 388
|
|
| NDP-sugDHase |
TIGR03026 |
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ... |
1-378 |
7.17e-125 |
|
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.
Pssm-ID: 274399 [Multi-domain] Cd Length: 409 Bit Score: 366.17 E-value: 7.17e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIA-QNHEVVALDIVQAKVDMLNQKKSPIVDKEIQDYLSN--KSLNFRATTDKEDAYREADFV 77
Cdd:TIGR03026 1 MKIAVIGLGYVGLPLAALLAdLGHDVTGVDIDQEKVDKLNKGKSPIYEPGLDELLAKalKAGRLRATTDYEEAIRDADVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 78 IIATPTDYDPkTNYFNTSTVEAVIKDVIA-INPNAVMIIKSTIPVGFT----KSIKEELGID-----NVFFSPEFLREGR 147
Cdd:TIGR03026 81 IICVPTPLKE-DGSPDLSYVESAAETIAKhLRKGATVVLESTVPPGTTeevvKPILERSGLKlgedfYLAYNPEFLREGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 148 ALYDNLHPSRIVIGERSERAERFAALLQEGAikkDIPVLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQ 227
Cdd:TIGR03026 160 AVHDLLHPDRIVGGETEEAGEAVAELYSPII---DGPVLVTSIETAEMIKLAENTFRAVKIAFANELARICEALGIDVYE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 228 IIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQA--VPNNLISAIVDANRTRKDFISDSILAR----QPKVVGV 301
Cdd:TIGR03026 237 VIEAAGTDPRIGFNFLNPGPGVGGHCIPKDPLALIAKAKElgYNPELIEAAREINDSQPDYVVEKIKDLlgplKGKTVLI 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2193613060 302 YRLIMKSGSDNFRASSIQGIMKRIKAKGVQVIIYEPAMQEDEFFHSRVVRDLDAFKKEADVIISNRMAEELADVADK 378
Cdd:TIGR03026 317 LGLAFKPNTDDVRESPALDIIELLKEKGAKVKAYDPLVPEEEVKGLPSIDDLEEALKGADALVILTDHSEFKDLDLE 393
|
|
| Ugd |
COG1004 |
UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis]; |
1-341 |
6.33e-76 |
|
UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440628 [Multi-domain] Cd Length: 436 Bit Score: 241.46 E-value: 6.33e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIAQ-NHEVVALDIVQAKVDMLNQKKSPI----VDKEIQDYLSNKSLNFraTTDKEDAYREAD 75
Cdd:COG1004 1 MKIAVIGTGYVGLVTAACLAElGHEVTCVDIDEEKIEALNAGEIPIyepgLEELVARNVAAGRLRF--TTDLAEAVAEAD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 76 FVIIA--TPTDYDpktNYFNTSTVEAVIKDVI-AINPNAVMIIKSTIPVGFTKSIK----EELGIDNVFFS----PEFLR 144
Cdd:COG1004 79 VVFIAvgTPSDED---GSADLSYVLAAARSIGeALKGYKVVVTKSTVPVGTADRVRaiiaEELRGAGVDFDvvsnPEFLR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 145 EGRALYDNLHPSRIVIGERSERAERFAALLQEGAIKKDIPVLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLN 224
Cdd:COG1004 156 EGSAVEDFLRPDRIVIGVDSERAAEVLRELYAPFVRNGTPIIVTDLRSAELIKYAANAFLATKISFINEIANLCEKVGAD 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 225 TRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQL--LANYQAVPNNLISAIVDANRTRKDFISDSILAR-----QPK 297
Cdd:COG1004 236 VEEVARGIGLDSRIGPKFLYAGIGYGGSCFPKDVRALiaTARELGYDLRLLEAVEEVNERQKRRLVEKIREHlggdlKGK 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 2193613060 298 VVGVYRLIMKSGSDNFR-ASSIQgIMKRIKAKGVQVIIYEP-AMQE 341
Cdd:COG1004 316 TIAVLGLAFKPNTDDMReSPALD-IIEALLEAGARVRAYDPvAMEN 360
|
|
| WecC |
COG0677 |
UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis]; |
2-364 |
1.88e-41 |
|
UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440441 [Multi-domain] Cd Length: 413 Bit Score: 150.60 E-value: 1.88e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 2 KITISGTGYVGLSNGILIAQN-HEVVALDIVQAKVDMLNQKKSPIV---DKEIQDYLSNKslNFRATTDkEDAYREADFV 77
Cdd:COG0677 1 KIAVIGLGYVGLPLAVAFAKAgFRVIGFDINPERVEELNAGEDPILepgDELLAEAVAAG--RLRATTD-PEALAEADVV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 78 IIATPTDYDpKTNYFNTSTVEAVIKDVIA-INPNAVMIIKSTIPVGFT----KSIKEE-----LGID-NVFFSPEflRE- 145
Cdd:COG0677 78 IIAVPTPLD-EDKEPDLSYLESASETIAPhLKPGDLVVLESTVYPGTTeevcVPILEKrsglkAGEDfFLAYSPE--RIn 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 146 -GRALYDNLHPSRIV--IGERSerAERFAALLQEGAIKKDIPVlfTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLG 222
Cdd:COG0677 155 pGNKLHELRNIPKVVggITPES--AERAAALYGSVVTAGVVPV--SSIKVAEAAKLIENTYRDVNIALANELALICDRLG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 223 LNTRQIIEGVCLDPRIGNHYnnPSFGYGGYCLPKDTKQLLANYQAVPNN--LISA---IVD------ANRTRKDFISDSI 291
Cdd:COG0677 231 IDVWEVIEAANTKPGFLIFY--PGPGVGGHCIPVDPYYLTWKARELGYHprLILAareINDsmpeyvVERVVKALNEAGK 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2193613060 292 LARQPKVVgVYRLIMKSGSDNFRASSIQGIMKRIKAKGVQVIIYEPAMQEDEFFH-SRVVRDLDAFKKEADVII 364
Cdd:COG0677 309 SLKGARVL-VLGLAYKENVDDLRESPALDIIEELREYGAEVDVHDPYVDEEEVEGeYGELVDLEEALEGADAVV 381
|
|
| UDPG_MGDP_dh_N |
pfam03721 |
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose ... |
1-176 |
5.69e-38 |
|
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.
Pssm-ID: 397677 [Multi-domain] Cd Length: 186 Bit Score: 135.07 E-value: 5.69e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIAQ-NHEVVALDIVQAKVDMLNQKKSPIVDKEIQDYL-SNKSLNFRATTDKEDAYREADFVI 78
Cdd:pfam03721 1 MKISVIGLGYVGLPTAACLAEiGHDVIGVDIDEEKVDKLNSGQIPIYEPGLDELVkANVSGRLSFTTDYSTAIEEADVIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 79 IATPTDYDPKTNYFNTSTVEAVIKDVI-AINPNAVMIIKSTIPVGFT----KSIKEEL----GID-NVFFSPEFLREGRA 148
Cdd:pfam03721 81 IAVGTPSKKGGGAADLKYVESAARSIApHLKKGKVVVVKSTVPVGTTenlvKPIIEEGgkkvGVDfDVASNPEFLREGSA 160
|
170 180
....*....|....*....|....*...
gi 2193613060 149 LYDNLHPSRIVIGERSERAErfaALLQE 176
Cdd:pfam03721 161 VYDLFNPDRVVIGVTEKCAE---AALEE 185
|
|
| UDPG_MGDP_dh |
pfam00984 |
UDP-glucose/GDP-mannose dehydrogenase family, central domain; The UDP-glucose/GDP-mannose ... |
192-281 |
3.27e-34 |
|
UDP-glucose/GDP-mannose dehydrogenase family, central domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.
Pssm-ID: 460015 [Multi-domain] Cd Length: 92 Bit Score: 121.72 E-value: 3.27e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 192 EAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQA--VP 269
Cdd:pfam00984 1 SAELIKLAENAFLAVKISFINELANLCEALGADVWEVIEAAGTDPRIGPKFLYPGPGVGGSCLPKDPRALIYLARElgVP 80
|
90
....*....|..
gi 2193613060 270 NNLISAIVDANR 281
Cdd:pfam00984 81 ARLLEAAREVNE 92
|
|
| PLN02353 |
PLN02353 |
probable UDP-glucose 6-dehydrogenase |
1-361 |
2.52e-25 |
|
probable UDP-glucose 6-dehydrogenase
Pssm-ID: 177986 [Multi-domain] Cd Length: 473 Bit Score: 107.07 E-value: 2.52e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIAQNH---EVVALDIVQAKVDMLNQKKSPIVD---KEIQDYLSNKSLNFraTTDKEDAYREA 74
Cdd:PLN02353 2 VKICCIGAGYVGGPTMAVIALKCpdiEVVVVDISVPRIDAWNSDQLPIYEpglDEVVKQCRGKNLFF--STDVEKHVAEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 75 D--FVIIATPTdydpKT---------NYFNTSTVEAVIKDVIaiNPNAVMIIKSTIPVGFTKSIKEEL-----GID-NVF 137
Cdd:PLN02353 80 DivFVSVNTPT----KTrglgagkaaDLTYWESAARMIADVS--KSDKIVVEKSTVPVKTAEAIEKILthnskGINfQIL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 138 FSPEFLREGRALYDNLHPSRIVIGERsERAERFAALlqegAIKKD-----IP---VLFTDSTEAEAIKLFANTYLAMRVA 209
Cdd:PLN02353 154 SNPEFLAEGTAIEDLFKPDRVLIGGR-ETPEGQKAV----QALKDvyahwVPeerIITTNLWSAELSKLAANAFLAQRIS 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 210 YFNELDSYAESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLL-----------ANY--QAVPNNlisai 276
Cdd:PLN02353 229 SVNAMSALCEATGADVSQVSHAVGKDSRIGPKFLNASVGFGGSCFQKDILNLVyicecnglpevAEYwkQVIKMN----- 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 277 vDANRTR--KDFISDSILARQPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGVQVIIYEPAMQEDEFFhsrvvRDLD 354
Cdd:PLN02353 304 -DYQKSRfvNRVVSSMFNTVSGKKIAVLGFAFKKDTGDTRETPAIDVCKGLLGDKAKLSIYDPQVTEEQIQ-----RDLS 377
|
....*..
gi 2193613060 355 AFKKEAD 361
Cdd:PLN02353 378 MNKFDWD 384
|
|
| UDPG_MGDP_dh_C |
smart00984 |
UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes ... |
300-385 |
1.06e-17 |
|
UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.
Pssm-ID: 214954 [Multi-domain] Cd Length: 99 Bit Score: 77.55 E-value: 1.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 300 GVYRLIMKSGSDNFRASSIQGIMKRIKAKGVQVIIYEP-AMQE-DEFFHSRVVRDLDAFKKEADVIISNRMAE------- 370
Cdd:smart00984 1 AVLGLAFKPNTDDLRESPALDIIEELLEAGAEVVVYDPyAMEEaREYGLTYVSDLEEALKGADAVVIATEHDEfrsldpe 80
|
90
....*....|....*...
gi 2193613060 371 ELADVADK---VYTRDLF 385
Cdd:smart00984 81 ELKDLMKKpvvVDGRNIL 98
|
|
| wecC |
PRK11064 |
UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional |
2-257 |
3.23e-12 |
|
UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional
Pssm-ID: 182940 [Multi-domain] Cd Length: 415 Bit Score: 67.32 E-value: 3.23e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 2 KITISGTGYVGLSNGILIAQ-NHEVVALDIVQAKVDMLNQKKSPIV----DKEIQDYLSNKSLnfRATTDKEdayrEADF 76
Cdd:PRK11064 5 TISVIGLGYIGLPTAAAFASrQKQVIGVDINQHAVDTINRGEIHIVepdlDMVVKTAVEGGYL--RATTTPE----PADA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 77 VIIATPT----DYDPKTNYfntstVEAVIKdviAINP----NAVMIIKSTIPVGFTKSIKEEL-------------GID- 134
Cdd:PRK11064 79 FLIAVPTpfkgDHEPDLTY-----VEAAAK---SIAPvlkkGDLVILESTSPVGATEQMAEWLaearpdltfpqqaGEQa 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 135 --NVFFSPEFLREGRALYDNLHPSRiVIG----ERSERAERFAALLQEGAikkdipVLFTDSTEAEAIKLFANTYLAMRV 208
Cdd:PRK11064 151 diNIAYCPERVLPGQVMVELIKNDR-VIGgmtpVCSARASELYKIFLEGE------CVVTNSRTAEMCKLTENSFRDVNI 223
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 2193613060 209 AYFNELDSYAESLGLNTRQIIEGVCLDPRIgnhyN--NPSFGYGGYCLPKD 257
Cdd:PRK11064 224 AFANELSLICADQGINVWELIRLANRHPRV----NilQPGPGVGGHCIAVD 270
|
|
| PRK15182 |
PRK15182 |
Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB; |
1-343 |
2.98e-08 |
|
Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB;
Pssm-ID: 185104 [Multi-domain] Cd Length: 425 Bit Score: 55.08 E-value: 2.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNQKKSPIVDKEIQDYLSNKSLNFRATTDKedaYREADFVIIA 80
Cdd:PRK15182 7 VKIAIIGLGYVGLPLAVEFGKSRQVVGFDVNKKRILELKNGVDVNLETTEEELREARYLKFTSEIEK---IKECNFYIIT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 81 TPTDYDPKTNYFNTSTVEAVIKDVIAINPNAVMIIKSTIPVGFTKS-----IKEELGID-----NVFFSPEFLREGRALY 150
Cdd:PRK15182 84 VPTPINTYKQPDLTPLIKASETVGTVLNRGDIVVYESTVYPGCTEEecvpiLARMSGMTfnqdfYVGYSPERINPGDKKH 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 151 DNLHPSRIVIGERSERAERFAALLQE----GAIKKD-IPVlftdsteAEAIKLFANTYLAMRVAYFNELDSYAESLGLNT 225
Cdd:PRK15182 164 RLTNIKKITSGSTAQIAELIDEVYQQiisaGTYKAEsIKV-------AEAAKVIENTQRDLNIALVNELAIIFNRLNIDT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 226 RQIIEGVcldpriGNHYNNPSFG---YGGYCLPKDTKQLLANYQAVpnNLISAIVDANRTRKD----FISDSILARQPK- 297
Cdd:PRK15182 237 EAVLRAA------GSKWNFLPFRpglVGGHCIGVDPYYLTHKSQGI--GYYPEIILAGRRLNDnmgnYVSEQLIKAMIKk 308
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 2193613060 298 ---VVGVYRLIM----KSGSDNFRASSIQGIMKRIKAKGVQVIIYEPAMQEDE 343
Cdd:PRK15182 309 ginVEGSSVLILgftfKENCPDIRNTRIIDVVKELGKYSCKVDIFDPWVDAEE 361
|
|
| UDPG_MGDP_dh_C |
pfam03720 |
UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; The UDP-glucose/GDP-mannose ... |
300-364 |
5.82e-08 |
|
UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.
Pssm-ID: 427462 [Multi-domain] Cd Length: 103 Bit Score: 50.27 E-value: 5.82e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2193613060 300 GVYRLIMKSGSDNFRASSIQGIMKRIKAKGVQVIIYEP----AMQEDEFFHSRVVRDLDAFKKEADVII 364
Cdd:pfam03720 1 AVLGLAFKPNTDDLRESPALDIIELLLEEGAEVKVYDPyvpeEAIEALGDGVTLVDDLEEALKGADAIV 69
|
|
| PanE |
COG1893 |
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of ... |
1-180 |
1.55e-04 |
|
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Pssm-ID: 441497 [Multi-domain] Cd Length: 305 Bit Score: 43.31 E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTG----YVGlsnGILIAQNHEVVALDiVQAKVDMLNQK----KSPIVDKEIQDylsnkslnFRATTDKEDAyR 72
Cdd:COG1893 1 MKIAILGAGaiggLLG---ARLARAGHDVTLVA-RGAHAEALRENglrlESPDGDRTTVP--------VPAVTDPEEL-G 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 73 EADFVIIATPTdYDpktnyfntstVEAVIKDVI-AINPNAVMIiksTI--PVGFTKSIKEELGIDNVFFS---PEFLREG 146
Cdd:COG1893 68 PADLVLVAVKA-YD----------LEAAAEALApLLGPDTVVL---SLqnGLGHEERLAEALGAERVLGGvvtIGATREE 133
|
170 180 190
....*....|....*....|....*....|....*...
gi 2193613060 147 RALYDNLHPSRIVIGER----SERAERFAALLQEGAIK 180
Cdd:COG1893 134 PGVVRHTGGGRLVLGELdggpSERLEALAELLEAAGIP 171
|
|
| gpsA |
PRK00094 |
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; |
1-83 |
3.48e-04 |
|
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
Pssm-ID: 234629 [Multi-domain] Cd Length: 325 Bit Score: 41.98 E-value: 3.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGYVGLSNGILIAQN-HEVVALDIVQAKVDMLNQkkspivDKEIQDYLSNKSL--NFRATTDKEDAYREADFV 77
Cdd:PRK00094 2 MKIAVLGAGSWGTALAIVLARNgHDVTLWARDPEQAAEINA------DRENPRYLPGIKLpdNLRATTDLAEALADADLI 75
|
....*.
gi 2193613060 78 IIATPT 83
Cdd:PRK00094 76 LVAVPS 81
|
|
| LDH_MDH_like |
cd00650 |
NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Members ... |
4-122 |
1.59e-03 |
|
NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Members of this family include ubiquitous enzymes like L-lactate dehydrogenases (LDH), L-2-hydroxyisocaproate dehydrogenases, and some malate dehydrogenases (MDH). LDH catalyzes the last step of glycolysis in which pyruvate is converted to L-lactate. MDH is one of the key enzymes in the citric acid cycle, facilitating both the conversion of malate to oxaloacetate and replenishing levels of oxalacetate by reductive carboxylation of pyruvate. The LDH/MDH-like proteins are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.
Pssm-ID: 133419 [Multi-domain] Cd Length: 263 Bit Score: 40.00 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 4 TISGTGYVG--LSNGILIAQNH---EVVALDIVQAKVDmlnqkkspIVDKEIQDYLSNKSL-NFRATTDKEDAYREADFV 77
Cdd:cd00650 3 VIGAGGNVGpaLAFGLADGSVLlaiELVLYDIDEEKLK--------GVAMDLQDAVEPLADiKVSITDDPYEAFKDADVV 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2193613060 78 IIAT-----PTDYDPKTNYFNTSTVEAVIKDVIAINPNAVMIIKSTiPVG 122
Cdd:cd00650 75 IITAgvgrkPGMGRLDLLKRNVPIVKEIGDNIEKYSPDAWIIVVSN-PVD 123
|
|
| GpsA |
COG0240 |
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ... |
1-83 |
5.35e-03 |
|
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 440010 [Multi-domain] Cd Length: 327 Bit Score: 38.48 E-value: 5.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2193613060 1 MKITISGTGyvglSNG----ILIAQN-HEVVALDIVQAKVDMLNQkkspivDKEIQDYLSNKSL--NFRATTDKEDAYRE 73
Cdd:COG0240 1 MKIAVLGAG----SWGtalaKVLARNgHEVTLWGRDPEVAEEINE------TRENPRYLPGVKLpeNLRATSDLEEALAG 70
|
90
....*....|
gi 2193613060 74 ADFVIIATPT 83
Cdd:COG0240 71 ADLVLLAVPS 80
|
|
| |
