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Conserved domains on  [gi|2207173148|ref|WP_241166163|]
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transposase, partial [Citrobacter freundii]

Protein Classification

transposase( domain architecture ID 11459289)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism; similar to Escherichia coli IS150 protein InsAB

CATH:  1.10.10.10
Gene Ontology:  GO:0006313|GO:0003677|GO:0004803
PubMed:  20885819

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
2-88 1.04e-27

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


:

Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 96.92  E-value: 1.04e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207173148   2 KKRNFSAEFKRESAQLVVDQNYTVADAAKAMDVGLSTMTRWVKQLRDERQGKTPKASPITPEQIEIRELRKKLQRIEMEN 81
Cdd:COG2963     4 KRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLGGFPGDGRTTPEQAEIRRLRKELRRLEMEN 83


                  ....*..
gi 2207173148  82 EILKKAT 88
Cdd:COG2963    84 DILKKAA 90
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
2-88 1.04e-27

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 96.92  E-value: 1.04e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207173148   2 KKRNFSAEFKRESAQLVVDQNYTVADAAKAMDVGLSTMTRWVKQLRDERQGKTPKASPITPEQIEIRELRKKLQRIEMEN 81
Cdd:COG2963     4 KRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLGGFPGDGRTTPEQAEIRRLRKELRRLEMEN 83


                  ....*..
gi 2207173148  82 EILKKAT 88
Cdd:COG2963    84 DILKKAA 90
transpos_IS3 NF033516
IS3 family transposase;
9-87 2.25e-20

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 83.77  E-value: 2.25e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207173148   9 EFKRESAQLVVDQNYTVADAAKAMDVGLSTMTRWVKQLRDERQGKTPKAS--PITPEQIEIRELRKKLQRIEMENEILKK 86
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGGEAADAGRLkeLLTPEEEENRRLKRELAELRLENEILKK 80


                  .
gi 2207173148  87 A 87
Cdd:NF033516   81 A 81
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 2-74 8.81e-11

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 53.13  E-value: 8.81e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2207173148   2 KKRNFSAEFKRESAQLVVDQNYTVADAAKAMDVGLSTMTRWVKQLRdERQGKTPKASPITPEQIEIRELRKKL 74
Cdd:pfam01527   3 KRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYE-GGMGASPARPRLTALEEENRRLKREL 74
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
2-88 1.04e-27

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 96.92  E-value: 1.04e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207173148   2 KKRNFSAEFKRESAQLVVDQNYTVADAAKAMDVGLSTMTRWVKQLRDERQGKTPKASPITPEQIEIRELRKKLQRIEMEN 81
Cdd:COG2963     4 KRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLGGFPGDGRTTPEQAEIRRLRKELRRLEMEN 83


                  ....*..
gi 2207173148  82 EILKKAT 88
Cdd:COG2963    84 DILKKAA 90
transpos_IS3 NF033516
IS3 family transposase;
9-87 2.25e-20

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 83.77  E-value: 2.25e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207173148   9 EFKRESAQLVVDQNYTVADAAKAMDVGLSTMTRWVKQLRDERQGKTPKAS--PITPEQIEIRELRKKLQRIEMENEILKK 86
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGGEAADAGRLkeLLTPEEEENRRLKRELAELRLENEILKK 80


                  .
gi 2207173148  87 A 87
Cdd:NF033516   81 A 81
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 2-74 8.81e-11

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 53.13  E-value: 8.81e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2207173148   2 KKRNFSAEFKRESAQLVVDQNYTVADAAKAMDVGLSTMTRWVKQLRdERQGKTPKASPITPEQIEIRELRKKL 74
Cdd:pfam01527   3 KRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYE-GGMGASPARPRLTALEEENRRLKREL 74
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
 1-73 7.09e-04

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 37.14  E-value: 7.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2207173148   1 MKKRNFSAEFKRESAQLVVDQNYTVADAAKAMDVGLSTMTRWVKQ--------LRDERQGKTPKAspITPEQIE-IRELR 71
Cdd:COG3415    17 LRKTKDAREARRLRAVLLLAEGLSVREIAERLGVSRSTVYRWLKRyregglagLKDRPRGGRPSK--LSDEQRErLLELL 94


                  ..
gi 2207173148  72 KK 73
Cdd:COG3415    95 RE 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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