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Conserved domains on  [gi|2212133718|ref|WP_242385158|]
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CDP-alcohol phosphatidyltransferase family protein [Phocaeicola sartorii]

Protein Classification

CDP-alcohol phosphatidyltransferase family protein( domain architecture ID 10001704)

CDP-alcohol phosphatidyltransferase family protein catalyzes the transfer of a substituted phosphate group from a cytidine-5'-diphosphate-linked donor to an alcohol acceptor, an essential reaction in the biosynthesis of phospholipids

CATH:  1.20.120.1760
EC:  2.7.8.-
Gene Ontology:  GO:0016780|GO:0008654|GO:0016020|GO:0000287
PubMed:  24923293|24573438|21259003|24942835
SCOP:  3002413

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PgsA COG0558
Phosphatidylglycerophosphate synthase [Lipid transport and metabolism]; ...
 46-107 1.90e-09

Phosphatidylglycerophosphate synthase [Lipid transport and metabolism]; Phosphatidylglycerophosphate synthase is part of the Pathway/BioSystem: Phospholipid biosynthesis


:

Pssm-ID: 440324 [Multi-domain]  Cd Length: 177  Bit Score: 56.02  E-value: 1.90e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2212133718  46 PNVVTVFSIILGIGAGVMFYYPDMKHTLIGILLLMWAnhYDSADGQLARLTGQKTQWGRMLD 107
Cdd:COG0558    12 PNQLTLLRILLVPVFALLLLLGGALLLALVLFLLAGL--TDALDGYLARRLGQVSRFGAFLD 71
 
Name Accession Description Interval E-value
PgsA COG0558
Phosphatidylglycerophosphate synthase [Lipid transport and metabolism]; ...
 46-107 1.90e-09

Phosphatidylglycerophosphate synthase [Lipid transport and metabolism]; Phosphatidylglycerophosphate synthase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440324 [Multi-domain]  Cd Length: 177  Bit Score: 56.02  E-value: 1.90e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2212133718  46 PNVVTVFSIILGIGAGVMFYYPDMKHTLIGILLLMWAnhYDSADGQLARLTGQKTQWGRMLD 107
Cdd:COG0558    12 PNQLTLLRILLVPVFALLLLLGGALLLALVLFLLAGL--TDALDGYLARRLGQVSRFGAFLD 71
CDP-OH_P_transf pfam01066
CDP-alcohol phosphatidyltransferase; All of these members have the ability to catalyze the ...
 46-110 4.69e-05

CDP-alcohol phosphatidyltransferase; All of these members have the ability to catalyze the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond and concomitant breaking of a phosphoride anhydride bond.


Pssm-ID: 460049 [Multi-domain]  Cd Length: 157  Bit Score: 42.93  E-value: 4.69e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2212133718  46 PNVVTVFSIILgIGAGVMFYYPDmKHTLIGILLLMWANHYDSADGQLARLTGQKTQWGRMLDGFA 110
Cdd:pfam01066   4 PNLLTLLRILL-VPVFVVLLLGP-GNRILAAVVFALAALTDFLDGKIARKLNQVTDFGKFLDPLA 66
 
Name Accession Description Interval E-value
PgsA COG0558
Phosphatidylglycerophosphate synthase [Lipid transport and metabolism]; ...
 46-107 1.90e-09

Phosphatidylglycerophosphate synthase [Lipid transport and metabolism]; Phosphatidylglycerophosphate synthase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440324 [Multi-domain]  Cd Length: 177  Bit Score: 56.02  E-value: 1.90e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2212133718  46 PNVVTVFSIILGIGAGVMFYYPDMKHTLIGILLLMWAnhYDSADGQLARLTGQKTQWGRMLD 107
Cdd:COG0558    12 PNQLTLLRILLVPVFALLLLLGGALLLALVLFLLAGL--TDALDGYLARRLGQVSRFGAFLD 71
CDP-OH_P_transf pfam01066
CDP-alcohol phosphatidyltransferase; All of these members have the ability to catalyze the ...
 46-110 4.69e-05

CDP-alcohol phosphatidyltransferase; All of these members have the ability to catalyze the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond and concomitant breaking of a phosphoride anhydride bond.


Pssm-ID: 460049 [Multi-domain]  Cd Length: 157  Bit Score: 42.93  E-value: 4.69e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2212133718  46 PNVVTVFSIILgIGAGVMFYYPDmKHTLIGILLLMWANHYDSADGQLARLTGQKTQWGRMLDGFA 110
Cdd:pfam01066   4 PNLLTLLRILL-VPVFVVLLLGP-GNRILAAVVFALAALTDFLDGKIARKLNQVTDFGKFLDPLA 66
EPT1 COG5050
sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases [Lipid transport and ...
 22-107 4.31e-03

sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases [Lipid transport and metabolism];


Pssm-ID: 444050  Cd Length: 176  Bit Score: 37.36  E-value: 4.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2212133718  22 FLDIYFNRPIGY---AWalffkklkVHPNVVTVFSII--LGIGAGVMFYYPDMKHTLIGILLLMWAN-HYDSADGQLARL 95
Cdd:COG5050    19 FLERYFLRWLAArlpAW--------VTPNLLTASGALgaLAIFVGYLASNGDTGAYLWLAPVGLIVYwFGDSLDGSLARR 90

                          90
                  ....*....|..
gi 2212133718  96 TGQKTQWGRMLD 107
Cdd:COG5050    91 TGISRPYGEFLD 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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