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Conserved domains on  [gi|2214430775|ref|WP_242834722|]
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flavin reductase [Acetobacterium dehalogenans]

Protein Classification

flavin reductase family protein( domain architecture ID 10091341)

flavin reductase family protein such as flavin reductase that catalyzes the reduction of FMN, and to a lesser extent, FAD, using NADH as an electron donor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RutF COG1853
FMN reductase RutF, DIM6/NTAB family [Energy production and conversion]; FMN reductase RutF, ...
 91-243 1.23e-37

FMN reductase RutF, DIM6/NTAB family [Energy production and conversion]; FMN reductase RutF, DIM6/NTAB family is part of the Pathway/BioSystem: Pyrimidine degradation


:

Pssm-ID: 441458  Cd Length: 160  Bit Score: 129.18  E-value: 1.23e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  91 KREALQTLLFNVSYGLYIISSI-KDEKLNGMVSNTFIQVTSTPLKASVCLGKGTLTSEYVRESGVFGVSILGKDNHDLIK 169
Cdd:COG1853     1 MPDAFRDALGRLAPGVAVVTTRdADGRPNGMTASSFTSVSLDPPLVLVSVAKSSDTLENIRETGEFVVNVLSEDQAELAN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775 170 HFGYQSGRDVDKFKT--LSYITGKTGCPGLLETLCFVECEVEQTIDLGTHYMFIGKVVDG--DGFSKEEPMTYA--YYHA 243
Cdd:COG1853    81 RFAGRSGRGVDKFAGagLTTASGEVGAPLLAEAPAWLECRVVDVIELGDHTLFIGEVVAVhvDEDVDGRPLLYLggRYRR 160
YotD super family cl27730
Rubrerythrin [Energy production and conversion];
35-81 1.09e-14

Rubrerythrin [Energy production and conversion];


The actual alignment was detected with superfamily member COG1592:

Pssm-ID: 441200 [Multi-domain]  Cd Length: 180  Bit Score: 69.85  E-value: 1.09e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2214430775  35 IEESEVIETVKEKKWRCTVCNYIHVGETPPDVCPVCGVGPEKFVLVE 81
Cdd:COG1592   134 LEAGKVFKKDEEVVWVCPVCGYIHEGKEAPEKCPVCGHPKSYFELFA 180
YotD super family cl27730
Rubrerythrin [Energy production and conversion];
2-36 3.12e-12

Rubrerythrin [Energy production and conversion];


The actual alignment was detected with superfamily member COG1592:

Pssm-ID: 441200 [Multi-domain]  Cd Length: 180  Bit Score: 62.91  E-value: 3.12e-12
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2214430775   2 KKWRCTVCNYVHEGDTPPDKCPICGVGPDKFVLIE 36
Cdd:COG1592   146 VVWVCPVCGYIHEGKEAPEKCPVCGHPKSYFELFA 180
 
Name Accession Description Interval E-value
RutF COG1853
FMN reductase RutF, DIM6/NTAB family [Energy production and conversion]; FMN reductase RutF, ...
 91-243 1.23e-37

FMN reductase RutF, DIM6/NTAB family [Energy production and conversion]; FMN reductase RutF, DIM6/NTAB family is part of the Pathway/BioSystem: Pyrimidine degradation


Pssm-ID: 441458  Cd Length: 160  Bit Score: 129.18  E-value: 1.23e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  91 KREALQTLLFNVSYGLYIISSI-KDEKLNGMVSNTFIQVTSTPLKASVCLGKGTLTSEYVRESGVFGVSILGKDNHDLIK 169
Cdd:COG1853     1 MPDAFRDALGRLAPGVAVVTTRdADGRPNGMTASSFTSVSLDPPLVLVSVAKSSDTLENIRETGEFVVNVLSEDQAELAN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775 170 HFGYQSGRDVDKFKT--LSYITGKTGCPGLLETLCFVECEVEQTIDLGTHYMFIGKVVDG--DGFSKEEPMTYA--YYHA 243
Cdd:COG1853    81 RFAGRSGRGVDKFAGagLTTASGEVGAPLLAEAPAWLECRVVDVIELGDHTLFIGEVVAVhvDEDVDGRPLLYLggRYRR 160
Flavin_Reduct pfam01613
Flavin reductase like domain; This is a flavin reductase family consisting of enzymes known to ...
 99-242 5.53e-36

Flavin reductase like domain; This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. VlmR is a flavin reductase that functions in a two-component enzyme system to provide isobutylamine N-hydroxylase with reduced flavin and may be involved in the synthesis of valanimycin. SnaC is a flavin reductase that provides reduced flavin for the oxidation of pristinamycin IIB to pristinamycin IIA as catalyzed by SnaA, SnaB heterodimer. This flavin reductase region characterized by enzymes of the family is present in the C-terminus of potential FMN proteins from Synechocystis sp. suggesting it is a flavin reductase domain.


Pssm-ID: 460266  Cd Length: 149  Bit Score: 124.70  E-value: 5.53e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  99 LFNVSYGLYIISSIKDEKLNGMVSNTFIQVTSTPLKASVCLGKGTLTSEYVRESGVFGVSILGKDNHDLIKHFGYQSGRd 178
Cdd:pfam01613   1 MRRFPTGVAVVTTDDGGEPNGMTVSSFTSVSLDPPLVLVSINRSSSTHDAIEASGEFVVNVLAEDQEELARRFAGRSGR- 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214430775 179 vDKFKTLSYITGKTGCPGLLETLCFVECEVEQTIDLGTHYMFIGKVVDGDGFSKEEPMTYAYYH 242
Cdd:pfam01613  80 -DKFAGITWVEGKVGAPLLKGALAALECRVVDTVDVGDHTLFIGEVVDVRVDEDADGEPLLYYR 142
Flavin_Reduct smart00903
Flavin reductase like domain; This entry represents the FMN-binding domain found in NAD(P) ...
 102-238 1.04e-32

Flavin reductase like domain; This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.


Pssm-ID: 214900  Cd Length: 147  Bit Score: 116.10  E-value: 1.04e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  102 VSYGLYIISSI--KDEKLNGMVSNtFIQVTSTPLKASVCLGKGTLTSEYVRESGVFGVSILGKDNHDLIKHFGYQSGRDV 179
Cdd:smart00903   4 FPTGVAVVTTRdgDGGRVGLTASS-FVSVSLDPPLVLVCVAKSSSTHPLIRESGRFVVNVLAEDQADLARRFAGKSGADR 82

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  180 DKFKTLSY-ITGKTGCPGLLETLCFVECEVEQTIDLGTHYMFIGKVVDGDGFSKEEPMTY 238
Cdd:smart00903  83 FEGVAWGLtEAGVTGAPILAGALAWLECRVVQVIEVGDHTIFVGEVVAVHVRDDGEPLVY 142
YotD COG1592
Rubrerythrin [Energy production and conversion];
35-81 1.09e-14

Rubrerythrin [Energy production and conversion];


Pssm-ID: 441200 [Multi-domain]  Cd Length: 180  Bit Score: 69.85  E-value: 1.09e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2214430775  35 IEESEVIETVKEKKWRCTVCNYIHVGETPPDVCPVCGVGPEKFVLVE 81
Cdd:COG1592   134 LEAGKVFKKDEEVVWVCPVCGYIHEGKEAPEKCPVCGHPKSYFELFA 180
YotD COG1592
Rubrerythrin [Energy production and conversion];
2-36 3.12e-12

Rubrerythrin [Energy production and conversion];


Pssm-ID: 441200 [Multi-domain]  Cd Length: 180  Bit Score: 62.91  E-value: 3.12e-12
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2214430775   2 KKWRCTVCNYVHEGDTPPDKCPICGVGPDKFVLIE 36
Cdd:COG1592   146 VVWVCPVCGYIHEGKEAPEKCPVCGHPKSYFELFA 180
rubredoxin_SM cd00729
Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present ...
 2-35 1.11e-11

Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and ferredoxin-thioredoxin reductase. In rubredoxin, the iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), and believed to be involved in electron transfer. Rubrerythrins and nigerythrins are small homodimeric proteins, generally consisting of 2 domains: a rubredoxin domain C-terminal to a non-sulfur, oxo-bridged diiron site in the N-terminal rubrerythrin domain. Rubrerythrins and nigerythrins have putative peroxide activity.


Pssm-ID: 238371 [Multi-domain]  Cd Length: 34  Bit Score: 57.59  E-value: 1.11e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2214430775   2 KKWRCTVCNYVHEGDTPPDKCPICGVGPDKFVLI 35
Cdd:cd00729     1 KVWVCPVCGYIHEGEEAPEKCPICGAPKEKFEEF 34
rubredoxin_SM cd00729
Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present ...
 47-80 1.69e-11

Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and ferredoxin-thioredoxin reductase. In rubredoxin, the iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), and believed to be involved in electron transfer. Rubrerythrins and nigerythrins are small homodimeric proteins, generally consisting of 2 domains: a rubredoxin domain C-terminal to a non-sulfur, oxo-bridged diiron site in the N-terminal rubrerythrin domain. Rubrerythrins and nigerythrins have putative peroxide activity.


Pssm-ID: 238371 [Multi-domain]  Cd Length: 34  Bit Score: 57.20  E-value: 1.69e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2214430775  47 KKWRCTVCNYIHVGETPPDVCPVCGVGPEKFVLV 80
Cdd:cd00729     1 KVWVCPVCGYIHEGEEAPEKCPICGAPKEKFEEF 34
hpaC PRK15486
4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional
 89-221 5.19e-06

4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional


Pssm-ID: 185383  Cd Length: 170  Bit Score: 45.42  E-value: 5.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  89 DKKREALQTLLFNVSYGLYIISSIKDEKLNGMVSNTFIQVTSTPLKASVCLGKGTLTSEYVRESGVFGVSILGKDNHDLI 168
Cdd:PRK15486    4 DEQRLRFRDAMASLSAAVNIVTTAGDAGRCGITATAVCSVTDTPPSVMVCINANSAMNPVFQGNGKLCINVLNHEQELMA 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2214430775 169 KHFGYQSGRDVDKFKTLS-YITGKTGCPGLLETLCFVECEVEQTIDLGTHYMFI 221
Cdd:PRK15486   84 RHFAGMTGMAMEERFSLScWQKGPLGQPVLKGSLASLEGEISDVQTIGTHLVYL 137
 
Name Accession Description Interval E-value
RutF COG1853
FMN reductase RutF, DIM6/NTAB family [Energy production and conversion]; FMN reductase RutF, ...
 91-243 1.23e-37

FMN reductase RutF, DIM6/NTAB family [Energy production and conversion]; FMN reductase RutF, DIM6/NTAB family is part of the Pathway/BioSystem: Pyrimidine degradation


Pssm-ID: 441458  Cd Length: 160  Bit Score: 129.18  E-value: 1.23e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  91 KREALQTLLFNVSYGLYIISSI-KDEKLNGMVSNTFIQVTSTPLKASVCLGKGTLTSEYVRESGVFGVSILGKDNHDLIK 169
Cdd:COG1853     1 MPDAFRDALGRLAPGVAVVTTRdADGRPNGMTASSFTSVSLDPPLVLVSVAKSSDTLENIRETGEFVVNVLSEDQAELAN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775 170 HFGYQSGRDVDKFKT--LSYITGKTGCPGLLETLCFVECEVEQTIDLGTHYMFIGKVVDG--DGFSKEEPMTYA--YYHA 243
Cdd:COG1853    81 RFAGRSGRGVDKFAGagLTTASGEVGAPLLAEAPAWLECRVVDVIELGDHTLFIGEVVAVhvDEDVDGRPLLYLggRYRR 160
Flavin_Reduct pfam01613
Flavin reductase like domain; This is a flavin reductase family consisting of enzymes known to ...
 99-242 5.53e-36

Flavin reductase like domain; This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. VlmR is a flavin reductase that functions in a two-component enzyme system to provide isobutylamine N-hydroxylase with reduced flavin and may be involved in the synthesis of valanimycin. SnaC is a flavin reductase that provides reduced flavin for the oxidation of pristinamycin IIB to pristinamycin IIA as catalyzed by SnaA, SnaB heterodimer. This flavin reductase region characterized by enzymes of the family is present in the C-terminus of potential FMN proteins from Synechocystis sp. suggesting it is a flavin reductase domain.


Pssm-ID: 460266  Cd Length: 149  Bit Score: 124.70  E-value: 5.53e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  99 LFNVSYGLYIISSIKDEKLNGMVSNTFIQVTSTPLKASVCLGKGTLTSEYVRESGVFGVSILGKDNHDLIKHFGYQSGRd 178
Cdd:pfam01613   1 MRRFPTGVAVVTTDDGGEPNGMTVSSFTSVSLDPPLVLVSINRSSSTHDAIEASGEFVVNVLAEDQEELARRFAGRSGR- 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214430775 179 vDKFKTLSYITGKTGCPGLLETLCFVECEVEQTIDLGTHYMFIGKVVDGDGFSKEEPMTYAYYH 242
Cdd:pfam01613  80 -DKFAGITWVEGKVGAPLLKGALAALECRVVDTVDVGDHTLFIGEVVDVRVDEDADGEPLLYYR 142
Flavin_Reduct smart00903
Flavin reductase like domain; This entry represents the FMN-binding domain found in NAD(P) ...
 102-238 1.04e-32

Flavin reductase like domain; This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.


Pssm-ID: 214900  Cd Length: 147  Bit Score: 116.10  E-value: 1.04e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  102 VSYGLYIISSI--KDEKLNGMVSNtFIQVTSTPLKASVCLGKGTLTSEYVRESGVFGVSILGKDNHDLIKHFGYQSGRDV 179
Cdd:smart00903   4 FPTGVAVVTTRdgDGGRVGLTASS-FVSVSLDPPLVLVCVAKSSSTHPLIRESGRFVVNVLAEDQADLARRFAGKSGADR 82

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  180 DKFKTLSY-ITGKTGCPGLLETLCFVECEVEQTIDLGTHYMFIGKVVDGDGFSKEEPMTY 238
Cdd:smart00903  83 FEGVAWGLtEAGVTGAPILAGALAWLECRVVQVIEVGDHTIFVGEVVAVHVRDDGEPLVY 142
YotD COG1592
Rubrerythrin [Energy production and conversion];
35-81 1.09e-14

Rubrerythrin [Energy production and conversion];


Pssm-ID: 441200 [Multi-domain]  Cd Length: 180  Bit Score: 69.85  E-value: 1.09e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2214430775  35 IEESEVIETVKEKKWRCTVCNYIHVGETPPDVCPVCGVGPEKFVLVE 81
Cdd:COG1592   134 LEAGKVFKKDEEVVWVCPVCGYIHEGKEAPEKCPVCGHPKSYFELFA 180
YotD COG1592
Rubrerythrin [Energy production and conversion];
2-36 3.12e-12

Rubrerythrin [Energy production and conversion];


Pssm-ID: 441200 [Multi-domain]  Cd Length: 180  Bit Score: 62.91  E-value: 3.12e-12
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2214430775   2 KKWRCTVCNYVHEGDTPPDKCPICGVGPDKFVLIE 36
Cdd:COG1592   146 VVWVCPVCGYIHEGKEAPEKCPVCGHPKSYFELFA 180
rubredoxin_SM cd00729
Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present ...
 2-35 1.11e-11

Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and ferredoxin-thioredoxin reductase. In rubredoxin, the iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), and believed to be involved in electron transfer. Rubrerythrins and nigerythrins are small homodimeric proteins, generally consisting of 2 domains: a rubredoxin domain C-terminal to a non-sulfur, oxo-bridged diiron site in the N-terminal rubrerythrin domain. Rubrerythrins and nigerythrins have putative peroxide activity.


Pssm-ID: 238371 [Multi-domain]  Cd Length: 34  Bit Score: 57.59  E-value: 1.11e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2214430775   2 KKWRCTVCNYVHEGDTPPDKCPICGVGPDKFVLI 35
Cdd:cd00729     1 KVWVCPVCGYIHEGEEAPEKCPICGAPKEKFEEF 34
rubredoxin_SM cd00729
Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present ...
 47-80 1.69e-11

Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and ferredoxin-thioredoxin reductase. In rubredoxin, the iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), and believed to be involved in electron transfer. Rubrerythrins and nigerythrins are small homodimeric proteins, generally consisting of 2 domains: a rubredoxin domain C-terminal to a non-sulfur, oxo-bridged diiron site in the N-terminal rubrerythrin domain. Rubrerythrins and nigerythrins have putative peroxide activity.


Pssm-ID: 238371 [Multi-domain]  Cd Length: 34  Bit Score: 57.20  E-value: 1.69e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2214430775  47 KKWRCTVCNYIHVGETPPDVCPVCGVGPEKFVLV 80
Cdd:cd00729     1 KVWVCPVCGYIHEGEEAPEKCPICGAPKEKFEEF 34
rubredoxin_like cd00350
Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family ...
 3-35 2.41e-10

Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and ferredoxin-thioredoxin reductase. In rubredoxin, the iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc and believed to be involved in electron transfer. Rubrerythrins and nigerythrins are small homodimeric proteins, generally consisting of 2 domains: a rubredoxin domain C-terminal to a non-sulfur, oxo-bridged diiron site in the N-terminal rubrerythrin domain. Rubrerythrins and nigerythrins have putative peroxide activity.


Pssm-ID: 238210 [Multi-domain]  Cd Length: 33  Bit Score: 54.10  E-value: 2.41e-10
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2214430775   3 KWRCTVCNYVHEGDTPPDKCPICGVGPDKFVLI 35
Cdd:cd00350     1 KYVCPVCGYIYDGEEAPWVCPVCGAPKDKFEKL 33
rubredoxin_like cd00350
Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family ...
 48-80 2.92e-10

Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and ferredoxin-thioredoxin reductase. In rubredoxin, the iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc and believed to be involved in electron transfer. Rubrerythrins and nigerythrins are small homodimeric proteins, generally consisting of 2 domains: a rubredoxin domain C-terminal to a non-sulfur, oxo-bridged diiron site in the N-terminal rubrerythrin domain. Rubrerythrins and nigerythrins have putative peroxide activity.


Pssm-ID: 238210 [Multi-domain]  Cd Length: 33  Bit Score: 53.71  E-value: 2.92e-10
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2214430775  48 KWRCTVCNYIHVGETPPDVCPVCGVGPEKFVLV 80
Cdd:cd00350     1 KYVCPVCGYIYDGEEAPWVCPVCGAPKDKFEKL 33
NorV COG1773
Flavorubredoxin [Inorganic ion transport and metabolism];
1-36 4.45e-06

Flavorubredoxin [Inorganic ion transport and metabolism];


Pssm-ID: 441379 [Multi-domain]  Cd Length: 53  Bit Score: 42.85  E-value: 4.45e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2214430775   1 MKKWRCTVCNYV---HEGD--------TP----PD--KCPICGVGPDKFVLIE 36
Cdd:COG1773     1 MKKYQCKVCGYVydpAEGDpengippgTPfedlPDdwVCPVCGAGKEDFEPVE 53
hpaC PRK15486
4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional
 89-221 5.19e-06

4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional


Pssm-ID: 185383  Cd Length: 170  Bit Score: 45.42  E-value: 5.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214430775  89 DKKREALQTLLFNVSYGLYIISSIKDEKLNGMVSNTFIQVTSTPLKASVCLGKGTLTSEYVRESGVFGVSILGKDNHDLI 168
Cdd:PRK15486    4 DEQRLRFRDAMASLSAAVNIVTTAGDAGRCGITATAVCSVTDTPPSVMVCINANSAMNPVFQGNGKLCINVLNHEQELMA 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2214430775 169 KHFGYQSGRDVDKFKTLS-YITGKTGCPGLLETLCFVECEVEQTIDLGTHYMFI 221
Cdd:PRK15486   84 RHFAGMTGMAMEERFSLScWQKGPLGQPVLKGSLASLEGEISDVQTIGTHLVYL 137
NorV COG1773
Flavorubredoxin [Inorganic ion transport and metabolism];
46-81 1.30e-04

Flavorubredoxin [Inorganic ion transport and metabolism];


Pssm-ID: 441379 [Multi-domain]  Cd Length: 53  Bit Score: 38.61  E-value: 1.30e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2214430775  46 EKKWRCTVCNYI---HVGE--------TP----PD--VCPVCGVGPEKFVLVE 81
Cdd:COG1773     1 MKKYQCKVCGYVydpAEGDpengippgTPfedlPDdwVCPVCGAGKEDFEPVE 53
rubredoxin cd00730
Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are ...
 3-35 7.96e-04

Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are believed to be involved in electron transfer.


Pssm-ID: 238372 [Multi-domain]  Cd Length: 50  Bit Score: 36.52  E-value: 7.96e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2214430775   3 KWRCTVCNYVH---EGD--------TP----PD--KCPICGVGPDKFVLI 35
Cdd:cd00730     1 KYECRICGYIYdpaEGDpdegippgTPfedlPDdwVCPVCGAGKDDFEPL 50
rubredoxin cd00730
Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are ...
 48-80 1.18e-03

Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are believed to be involved in electron transfer.


Pssm-ID: 238372 [Multi-domain]  Cd Length: 50  Bit Score: 36.13  E-value: 1.18e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2214430775  48 KWRCTVCNYIH---VGE--------TP----PD--VCPVCGVGPEKFVLV 80
Cdd:cd00730     1 KYECRICGYIYdpaEGDpdegippgTPfedlPDdwVCPVCGAGKDDFEPL 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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