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Conserved domains on  [gi|2214694677|ref|WP_242945093|]
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ribosomal L7Ae/L30e/S12e/Gadd45 family protein [Caminicella sporogenes]

Protein Classification

ribosomal L7Ae/L30e/S12e/Gadd45 family protein( domain architecture ID 624)

ribosomal L7Ae/L30e/S12e/Gadd45 family protein may be characterized as a K-turn binding protein; K-turns are RNA motifs comprised of a bulge flanked by canonical and noncanonical helices.

Gene Ontology:  GO:0005840
SCOP:  4001513

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_L7Ae super family cl00600
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 11-82 7.63e-23

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


The actual alignment was detected with superfamily member PRK13602:

Pssm-ID: 469835 [Multi-domain]  Cd Length: 82  Bit Score: 83.29  E-value: 7.63e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214694677 11 KLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIEIAKEKNVQIVYVDSMKKLGKACGIDVGAATAVILK 82
Cdd:PRK13602  11 SIVIGTKQTVKALKRGSVKEVVVAEDADPRLTEKVEALANEKGVPVSKVDSMKKLGKACGIEVGAAAVAIIK 82
 
Name Accession Description Interval E-value
PRK13602 PRK13602
50S ribosomal protein L7ae-like protein;
11-82 7.63e-23

50S ribosomal protein L7ae-like protein;


Pssm-ID: 184174 [Multi-domain]  Cd Length: 82  Bit Score: 83.29  E-value: 7.63e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214694677 11 KLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIEIAKEKNVQIVYVDSMKKLGKACGIDVGAATAVILK 82
Cdd:PRK13602  11 SIVIGTKQTVKALKRGSVKEVVVAEDADPRLTEKVEALANEKGVPVSKVDSMKKLGKACGIEVGAAAVAIIK 82
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 6-82 2.80e-15

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 64.41  E-value: 2.80e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2214694677  6 LKKQNKLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIEIAKEKNVQIVYVDSMKKLGKACGiDVGAATAVILK 82
Cdd:COG1358   10 ARRAGKLVSGEEQVLKAIRKGKAKLVIIAEDASENTKKKLLDLCEEYGVPVVEVGTKEELGKAIG-KVGRAVVAITD 85
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 3-81 2.88e-08

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 46.43  E-value: 2.88e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214694677  3 LMELKKQNKLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIE-IAKEKNVQIVYVDSMKKLGKACGIDVGAATAVIL 81
Cdd:pfam01248  7 LKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPaLCKEKNVPYVKVPSKKELGEACGKKRPVSALAIK 86
SNU13 cd21104
U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, ...
 3-71 8.39e-05

U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, also known as NHP2-like protein 1 or U4/U6.U5 tri-snRNP 15.5 kDa protein, is a component of the spliceosome B complex, involved in pre-mRNA splicing. It binds to the 5'-stem-loop of U4 snRNA.


Pssm-ID: 411046  Cd Length: 122  Bit Score: 38.08  E-value: 8.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214694677   3 LMELKKQ----NKLKVGTKQSTRALNEDKVATLFVAKDSEQhvvrniIEI-------AKEKNVQIVYVDSMKKLGKACGI 71
Cdd:cd21104    16 ILDLVQQaanyKQLKKGANEATKTLNRGIAEFIVMAADAEP------LEIllhlpllCEDKNVPYVFVPSKQALGRACGV 89
 
Name Accession Description Interval E-value
PRK13602 PRK13602
50S ribosomal protein L7ae-like protein;
11-82 7.63e-23

50S ribosomal protein L7ae-like protein;


Pssm-ID: 184174 [Multi-domain]  Cd Length: 82  Bit Score: 83.29  E-value: 7.63e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214694677 11 KLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIEIAKEKNVQIVYVDSMKKLGKACGIDVGAATAVILK 82
Cdd:PRK13602  11 SIVIGTKQTVKALKRGSVKEVVVAEDADPRLTEKVEALANEKGVPVSKVDSMKKLGKACGIEVGAAAVAIIK 82
PRK13601 PRK13601
putative L7Ae-like ribosomal protein; Provisional
 11-82 3.52e-20

putative L7Ae-like ribosomal protein; Provisional


Pssm-ID: 184173  Cd Length: 82  Bit Score: 76.56  E-value: 3.52e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214694677 11 KLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIEIAKEKNVQIVYVDSMKKLGKACGIDVGAATAVILK 82
Cdd:PRK13601   8 KRVVGAKQTLKAITNCNVLQVYIAKDAEEHVTKKIKELCEEKSIKIVYIDTMKELGVMCGIDVGAAAAADII 79
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 6-82 2.80e-15

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 64.41  E-value: 2.80e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2214694677  6 LKKQNKLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIEIAKEKNVQIVYVDSMKKLGKACGiDVGAATAVILK 82
Cdd:COG1358   10 ARRAGKLVSGEEQVLKAIRKGKAKLVIIAEDASENTKKKLLDLCEEYGVPVVEVGTKEELGKAIG-KVGRAVVAITD 85
PRK13600 PRK13600
putative ribosomal protein L7Ae-like; Provisional
 14-82 8.83e-09

putative ribosomal protein L7Ae-like; Provisional


Pssm-ID: 184172  Cd Length: 84  Bit Score: 47.54  E-value: 8.83e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214694677 14 VGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIEIAKEKNVQIVYVDSMKKLGKACGIDVGAATAVILK 82
Cdd:PRK13600  16 VGLKETLKALKKDQVTSLIIAEDVEVYLMTRVLSQINQKNIPVSFFKSKHALGKHVGINVNATIVALIK 84
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 3-81 2.88e-08

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 46.43  E-value: 2.88e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214694677  3 LMELKKQNKLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIE-IAKEKNVQIVYVDSMKKLGKACGIDVGAATAVIL 81
Cdd:pfam01248  7 LKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPaLCKEKNVPYVKVPSKKELGEACGKKRPVSALAIK 86
PRK06683 PRK06683
hypothetical protein; Provisional
 1-81 9.50e-08

hypothetical protein; Provisional


Pssm-ID: 136002  Cd Length: 82  Bit Score: 44.68  E-value: 9.50e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214694677  1 MHLMELKKQNKLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIEIAKEKNVQIVYVDSMKKLGKACGIDVGAATAVI 80
Cdd:PRK06683   1 MSYQKVSNAENVVVGHKRTLEAIKNGIVKEVVIAEDADMRLTHVIIRTALQHNIPITKVESVRKLGKVAGIQVGASAIGI 80


                 .
gi 2214694677 81 L 81
Cdd:PRK06683  81 I 81
SNU13 cd21104
U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, ...
 3-71 8.39e-05

U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, also known as NHP2-like protein 1 or U4/U6.U5 tri-snRNP 15.5 kDa protein, is a component of the spliceosome B complex, involved in pre-mRNA splicing. It binds to the 5'-stem-loop of U4 snRNA.


Pssm-ID: 411046  Cd Length: 122  Bit Score: 38.08  E-value: 8.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214694677   3 LMELKKQ----NKLKVGTKQSTRALNEDKVATLFVAKDSEQhvvrniIEI-------AKEKNVQIVYVDSMKKLGKACGI 71
Cdd:cd21104    16 ILDLVQQaanyKQLKKGANEATKTLNRGIAEFIVMAADAEP------LEIllhlpllCEDKNVPYVFVPSKQALGRACGV 89
RPL30E COG1911
Ribosomal protein L30E [Translation, ribosomal structure and biogenesis]; Ribosomal protein ...
 8-70 1.39e-03

Ribosomal protein L30E [Translation, ribosomal structure and biogenesis]; Ribosomal protein L30E is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441515 [Multi-domain]  Cd Length: 97  Bit Score: 34.42  E-value: 1.39e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214694677  8 KQNKLKVGTKQSTRALNEDKVATLFVAKDSEQHVVRNIIEIAKEKNVQI-VYVDSMKKLGKACG 70
Cdd:COG1911   13 KTGKVVLGSKQTIKAIKLGKAKLVILAANCPPEIREDIEYYAKLSNVPVyVYPGTSVELGALCG 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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