NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2227482804|ref|WP_246712397|]
View 

calcium-binding protein [Rhizobium leguminosarum]

Protein Classification

calcium-binding protein( domain architecture ID 11458495)

RTX toxin-related calcium-binding protein belongs to the serralysin-like M10 metalloprotease family, such as Bordetella pertussis adenylate cyclase toxin

CATH:  2.150.10.10|3.40.390.10
Gene Ontology:  GO:0005509
PubMed:  32860773|27058787|1558765
SCOP:  4002779|3001975

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COG2931 COG2931
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ...
 14-266 3.61e-09

Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 442175 [Multi-domain]  Cd Length: 252  Bit Score: 56.84  E-value: 3.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  14 GGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADSLAGAAGNDTLIG 93
Cdd:COG2931     1 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGDGGGGGGGGGGGGGGGGLDGGGGGGGGDGGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  94 GSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALANTITGGAGNDTL 173
Cdd:COG2931    81 GGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 174 NGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNlASYTLAANVENLSFAGTGPFAGTGNALNNVIVGGSGSN 253
Cdd:COG2931   161 YGGAGNDTLDGGAGNDTLTGGAGNDTLTGGAGNDTLDGGGG-DDTLGGGGGDDGLDGGDGDDGLGGGGGDDTLGGGGGGD 239

                         250
                  ....*....|...
gi 2227482804 254 TLTGGAGNDTLTG 266
Cdd:COG2931   240 GGGGGGGDDGLGG 252
 
Name Accession Description Interval E-value
COG2931 COG2931
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ...
 14-266 3.61e-09

Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442175 [Multi-domain]  Cd Length: 252  Bit Score: 56.84  E-value: 3.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  14 GGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADSLAGAAGNDTLIG 93
Cdd:COG2931     1 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGDGGGGGGGGGGGGGGGGLDGGGGGGGGDGGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  94 GSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALANTITGGAGNDTL 173
Cdd:COG2931    81 GGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 174 NGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNlASYTLAANVENLSFAGTGPFAGTGNALNNVIVGGSGSN 253
Cdd:COG2931   161 YGGAGNDTLDGGAGNDTLTGGAGNDTLTGGAGNDTLDGGGG-DDTLGGGGGDDGLDGGDGDDGLGGGGGDDTLGGGGGGD 239

                         250
                  ....*....|...
gi 2227482804 254 TLTGGAGNDTLTG 266
Cdd:COG2931   240 GGGGGGGDDGLGG 252
Peptidase_M10_C pfam08548
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ...
 224-288 4.95e-07

Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.


Pssm-ID: 430067 [Multi-domain]  Cd Length: 222  Bit Score: 50.06  E-value: 4.95e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 224 VENlSFAGTGPFAGTGNALNNVIVGGSGSNTLTGGAGNDTLTGGAAADVFVYL-----LNWGHDTITNFV 288
Cdd:pfam08548  81 IEN-AIGGSGNDVLIGNDADNILKGGAGNDILYGGGGADQLWGGAGNDIFVYAsakdsLTAAPDTIRDFV 149
34 PHA02584
long tail fiber, proximal subunit; Provisional
 146-300 9.76e-03

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 37.81  E-value: 9.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  146 TYTGSASFTGTGNALANTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNLASYTLAANVE 225
Cdd:PHA02584   906 TVNGSLTFTKNTNLSAPLVSSSTATFGGSVTANSTLTTQNTSNGTVVVVDETSIAFYSQNNTTGNIVFNIDGTVDPINVN 985

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2227482804  226 nlsfaGTGPFAGTGNALNNVIVGGSGSNTLTGGAGNDTLTGGAAADvfvyllnwGHDTITNFVATGAAHDTIRID 300
Cdd:PHA02584   986 -----ANGTLNATGVATNGRAVYAEGGGIARTNNAARAITGGFTIR--------NDGSTTVFLLTAAGDQTGGFN 1047
 
Name Accession Description Interval E-value
COG2931 COG2931
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ...
 14-266 3.61e-09

Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442175 [Multi-domain]  Cd Length: 252  Bit Score: 56.84  E-value: 3.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  14 GGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADSLAGAAGNDTLIG 93
Cdd:COG2931     1 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGDGGGGGGGGGGGGGGGGLDGGGGGGGGDGGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  94 GSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALANTITGGAGNDTL 173
Cdd:COG2931    81 GGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 174 NGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNlASYTLAANVENLSFAGTGPFAGTGNALNNVIVGGSGSN 253
Cdd:COG2931   161 YGGAGNDTLDGGAGNDTLTGGAGNDTLTGGAGNDTLDGGGG-DDTLGGGGGDDGLDGGDGDDGLGGGGGDDTLGGGGGGD 239

                         250
                  ....*....|...
gi 2227482804 254 TLTGGAGNDTLTG 266
Cdd:COG2931   240 GGGGGGGDDGLGG 252
COG2931 COG2931
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ...
 41-329 7.87e-09

Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442175 [Multi-domain]  Cd Length: 252  Bit Score: 55.68  E-value: 7.87e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  41 NLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADSLAGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATDIVIE 120
Cdd:COG2931     1 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGDGGGGGGGGGGGGGGGGLDGGGGGGGGDGGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 121 NVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALANTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLV 200
Cdd:COG2931    81 GGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 201 TevadegtdtvrtnlasytlaanvenlsfagtgpfagtGNALNNVIVGGSGSNTLTGGAGNDTLTGGAAADVFVYLLNWG 280
Cdd:COG2931   161 Y-------------------------------------GGAGNDTLDGGAGNDTLTGGAGNDTLTGGAGNDTLDGGGGDD 203

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 2227482804 281 HDTITNFVATGAAHDTIRIDHNIFADWESLFAASSQYGNDTIVTADIDN 329
Cdd:COG2931   204 TLGGGGGDDGLDGGDGDDGLGGGGGDDTLGGGGGGDGGGGGGGDDGLGG 252
COG2931 COG2931
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ...
 23-274 1.01e-08

Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442175 [Multi-domain]  Cd Length: 252  Bit Score: 55.30  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  23 AGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADSLAGAAGNDTLIGGSGADKMSG 102
Cdd:COG2931     1 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGDGGGGGGGGGGGGGGGGLDGGGGGGGGDGGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 103 GMGDDVYVVDIATDIVIENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALANTITGGAGNDTLNGAAGADTL 182
Cdd:COG2931    81 GGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 183 IGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNLASYTLAANVENLSFaGTGPFAGTGNALNNVIVGGSGSNTLTGGAGND 262
Cdd:COG2931   161 YGGAGNDTLDGGAGNDTLTGGAGNDTLTGGAGNDTLDGGGGDDTLGG-GGGDDGLDGGDGDDGLGGGGGDDTLGGGGGGD 239

                         250
                  ....*....|..
gi 2227482804 263 TLTGGAAADVFV 274
Cdd:COG2931   240 GGGGGGGDDGLG 251
COG2931 COG2931
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ...
 3-201 3.73e-08

Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442175 [Multi-domain]  Cd Length: 252  Bit Score: 53.76  E-value: 3.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   3 GAGADRLIGGAGGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADSL 82
Cdd:COG2931    54 GGGGGGGGGGGGGLDGGGGGGGGDGGGGGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTL 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  83 AGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVQtALSGYTLGNNVENLTYTGSASFTGTGNALAN 162
Cdd:COG2931   134 YGGAGNDTLTGGAGNDTLYGGAGNDTLYGGAGNDTLDGGAGNDTLTGG-AGNDTLTGGAGNDTLDGGGGDDTLGGGGGDD 212

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2227482804 163 TITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVT 201
Cdd:COG2931   213 GLDGGDGDDGLGGGGGDDTLGGGGGGDGGGGGGGDDGLG 251
COG2931 COG2931
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ...
 53-342 3.00e-07

Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442175 [Multi-domain]  Cd Length: 252  Bit Score: 51.06  E-value: 3.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  53 NLTYIGTATFVGTGNLLDNVITGGVGADSLAGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVQTA 132
Cdd:COG2931     4 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGDGGGGGGGGGGGGGGGGLDGGGGGGGGDGGGGGG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 133 LSGYTLGNNVENLTYTGSASFTGTGNALANTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTevadegtdtvr 212
Cdd:COG2931    84 GDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLY----------- 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 213 tnlasytlaanvenlsfagtgpfagtGNALNNVIVGGSGSNTLTGGAGNDTLTGGAAADVFVyllnWGHDTITNFVATGA 292
Cdd:COG2931   153 --------------------------GGAGNDTLYGGAGNDTLDGGAGNDTLTGGAGNDTLT----GGAGNDTLDGGGGD 202

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 2227482804 293 AHDTIRIDHNIFADWESLFAASSQYGNDTIVTADIDNTIVLRNVALTSLD 342
Cdd:COG2931   203 DTLGGGGGDDGLDGGDGDDGLGGGGGDDTLGGGGGGDGGGGGGGDDGLGG 252
COG2931 COG2931
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ...
 2-190 4.33e-07

Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442175 [Multi-domain]  Cd Length: 252  Bit Score: 50.67  E-value: 4.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   2 AGAGADRLIGGAGGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADS 81
Cdd:COG2931    62 GGGGGLDGGGGGGGGDGGGGGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDT 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  82 LAGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVqTALSGYTLGNNVENLTYTGSASFTGTGNALA 161
Cdd:COG2931   142 LTGGAGNDTLYGGAGNDTLYGGAGNDTLDGGAGNDTLTGGAGNDTLTG-GAGNDTLDGGGGDDTLGGGGGDDGLDGGDGD 220

                         170       180
                  ....*....|....*....|....*....
gi 2227482804 162 NTITGGAGNDTLNGAAGADTLIGRAGNDT 190
Cdd:COG2931   221 DGLGGGGGDDTLGGGGGGDGGGGGGGDDG 249
Peptidase_M10_C pfam08548
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ...
 224-288 4.95e-07

Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.


Pssm-ID: 430067 [Multi-domain]  Cd Length: 222  Bit Score: 50.06  E-value: 4.95e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 224 VENlSFAGTGPFAGTGNALNNVIVGGSGSNTLTGGAGNDTLTGGAAADVFVYL-----LNWGHDTITNFV 288
Cdd:pfam08548  81 IEN-AIGGSGNDVLIGNDADNILKGGAGNDILYGGGGADQLWGGAGNDIFVYAsakdsLTAAPDTIRDFV 149
COG2931 COG2931
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ...
 2-247 6.67e-07

Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442175 [Multi-domain]  Cd Length: 252  Bit Score: 49.90  E-value: 6.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   2 AGAGADRLIGGAGGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADS 81
Cdd:COG2931    44 GGGGGGDGGGGGGGGGGGGGGGGLDGGGGGGGGDGGGGGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDT 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  82 LAGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATDIVIenvnegtdtvqtalsgytlgnnvenltytgsasftgtGNALA 161
Cdd:COG2931   124 LTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTLY-------------------------------------GGAGN 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 162 NTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNLASYTLAANVENLSFAGTGPFAGTGNA 241
Cdd:COG2931   167 DTLDGGAGNDTLTGGAGNDTLTGGAGNDTLDGGGGDDTLGGGGGDDGLDGGDGDDGLGGGGGDDTLGGGGGGDGGGGGGG 246


                  ....*.
gi 2227482804 242 LNNVIV 247
Cdd:COG2931   247 DDGLGG 252
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 10-346 1.27e-05

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 47.07  E-value: 1.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   10 IGGAGGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADSLAGAAGND 89
Cdd:COG3210    814 VTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANA 893

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   90 TLIGGSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALANTITGGAG 169
Cdd:COG3210    894 GTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAG 973

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  170 NDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNLASYTLAANVENLSFAGTGPFAGTGNALNNVIVGG 249
Cdd:COG3210    974 SSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGI 1053

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  250 SGSNTLTGGAGNDTLTGGAAADVFVYLLNWGHDTITNFVATGAAHDTIRIDHNIFADWESLFAASSQYGNDTIVTADIDN 329
Cdd:COG3210   1054 SGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTS 1133

                          330
                   ....*....|....*..
gi 2227482804  330 TIVLRNVALTSLDSGDF 346
Cdd:COG3210   1134 TASTEAAGAGTLTGLVA 1150
Peptidase_M10_C pfam08548
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ...
 157-212 3.51e-05

Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.


Pssm-ID: 430067 [Multi-domain]  Cd Length: 222  Bit Score: 44.29  E-value: 3.51e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2227482804 157 GNALANTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVR 212
Cdd:pfam08548  95 GNDADNILKGGAGNDILYGGGGADQLWGGAGNDIFVYASAKDSLTAAPDTIRDFVS 150
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 2-272 1.49e-04

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 43.99  E-value: 1.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804    2 AGAGADRLIGGAGGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADS 81
Cdd:COG3210    433 LGITGNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIAT 512

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   82 LAGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALA 161
Cdd:COG3210    513 GLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGT 592

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  162 NTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNLASYTLAANVENLSFAGTGPFAGTGNA 241
Cdd:COG3210    593 GTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGG 672

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 2227482804  242 LNNVIVGGSGS-----NTLTGGAGNDTLTGGAAADV 272
Cdd:COG3210    673 GTTGTVTSGATggttgTTLNAATGGTLNNAGNTLTI 708
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 2-266 8.42e-04

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 41.30  E-value: 8.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   2 AGAGADRLIGGAGGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADS 81
Cdd:COG4625   217 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGG 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  82 LAGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNAlA 161
Cdd:COG4625   297 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGG-G 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 162 NTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNLASYTLAANVENLSFAGTGPFAGTGNA 241
Cdd:COG4625   376 GSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGG 455

                         250       260
                  ....*....|....*....|....*
gi 2227482804 242 LNNVIVGGSGSNTLTGGAGNDTLTG 266
Cdd:COG4625   456 AGGSGGGAGAGGGSGSGAGTLTLTG 480
HemolysinCabind pfam00353
RTX calcium-binding nonapeptide repeat (4 copies);
156-190 2.31e-03

RTX calcium-binding nonapeptide repeat (4 copies);


Pssm-ID: 459777 [Multi-domain]  Cd Length: 36  Bit Score: 35.11  E-value: 2.31e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2227482804 156 TGNALANTITGGAGNDTLNGAAGADTLIGRAGNDT 190
Cdd:pfam00353   1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDT 35
Peptidase_M10_C pfam08548
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ...
 70-116 3.78e-03

Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.


Pssm-ID: 430067 [Multi-domain]  Cd Length: 222  Bit Score: 38.12  E-value: 3.78e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2227482804  70 DNVITGGVGADSLAGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATD 116
Cdd:pfam08548  90 NDVLIGNDADNILKGGAGNDILYGGGGADQLWGGAGNDIFVYASAKD 136
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 2-276 4.00e-03

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 38.99  E-value: 4.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   2 AGAGADRLIGGAGGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADS 81
Cdd:COG4625   268 GGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGG 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  82 LAGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATDIVIENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALA 161
Cdd:COG4625   348 GGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGT 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804 162 NTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNLASYTLAANVE---NLSFAGTGPFAGT 238
Cdd:COG4625   428 GAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTGTTTVNgggNYTQSAGSTLAVE 507

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 2227482804 239 GNALNNVIVGGSGSNTLTGGAGNDTLTGGAAADVFVYL 276
Cdd:COG4625   508 VDAANSDRLVVTGTATLNGGTVVVLAGGYAPGTTYTIL 545
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 40-345 6.28e-03

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 38.59  E-value: 6.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   40 TNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADSLAGAAGNDTLIGGSGADKMSGGMGDDVYVVDIATDIVI 119
Cdd:COG3210    770 TTLTLANANGNTSAGATLDNAGAEISIDITADGTITAAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTT 849

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  120 ENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALANTITGGAGNDTLNGAAGADTLIGR-AGNDTYIIDNAGD 198
Cdd:COG3210    850 TGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATvTATGTGGGGLTGG 929

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  199 LVTEVADEGTDTVRTNLASYTLAANVENLSFAGTGPFAGTGNALNNVIVGGSGSNTLTGGAGNDTLTGGAAADVFVYLLN 278
Cdd:COG3210    930 NAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTT 1009

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2227482804  279 WGHDTITNFVATGAAHDTIRIDHNIFADWESLFAASSQYGNDTIVTADIDNTIVLRNVALTSLDSGD 345
Cdd:COG3210   1010 GGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAAS 1076
HemolysinCabind pfam00353
RTX calcium-binding nonapeptide repeat (4 copies);
74-108 7.40e-03

RTX calcium-binding nonapeptide repeat (4 copies);


Pssm-ID: 459777 [Multi-domain]  Cd Length: 36  Bit Score: 33.95  E-value: 7.40e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2227482804  74 TGGVGADSLAGAAGNDTLIGGSGADKMSGGMGDDV 108
Cdd:pfam00353   1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDT 35
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 2-293 8.80e-03

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 38.21  E-value: 8.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804    2 AGAGADRLIGGAGGDTYIVDNAGDLVTEAANEGIDTVRTNLSAYVLGANVENLTYIGTATFVGTGNLLDNVITGGVGADS 81
Cdd:COG3210    492 TVTTNATISNNAGGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLA 571

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804   82 LAGAAGNDTLIGGSGADkmSGGMGDDVYVVDIATDIVIENVNEGTDTVQTALSGYTLGNNVENLTYTGSASFTGTGNALA 161
Cdd:COG3210    572 ATGGTSNATTAGNSTSA--TGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSG 649

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  162 NTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNLASYTLAANVENLSFAGTGPFAGTGNA 241
Cdd:COG3210    650 TTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGSITVTGQIGALANANGDT 729

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2227482804  242 LNNVIVGGSGSNTLTGGAGNDTLTGGAAADVFVYLLNWGHDTITNFVATGAA 293
Cdd:COG3210    730 VTFGNLGTGATLTLNAGVTITSGNAGTLSIGLTANTTASGTTLTLANANGNT 781
34 PHA02584
long tail fiber, proximal subunit; Provisional
 146-300 9.76e-03

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 37.81  E-value: 9.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2227482804  146 TYTGSASFTGTGNALANTITGGAGNDTLNGAAGADTLIGRAGNDTYIIDNAGDLVTEVADEGTDTVRTNLASYTLAANVE 225
Cdd:PHA02584   906 TVNGSLTFTKNTNLSAPLVSSSTATFGGSVTANSTLTTQNTSNGTVVVVDETSIAFYSQNNTTGNIVFNIDGTVDPINVN 985

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2227482804  226 nlsfaGTGPFAGTGNALNNVIVGGSGSNTLTGGAGNDTLTGGAAADvfvyllnwGHDTITNFVATGAAHDTIRID 300
Cdd:PHA02584   986 -----ANGTLNATGVATNGRAVYAEGGGIARTNNAARAITGGFTIR--------NDGSTTVFLLTAAGDQTGGFN 1047
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH