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Conserved domains on  [gi|2246628406|ref|WP_250207038|]
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contractile injection system protein, VgrG/Pvc8 family, partial [Escherichia coli]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VgrG super family cl34624
Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly ...
 1-93 1.49e-14

Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly [Intracellular trafficking, secretion, and vesicular transport, Mobilome: prophages, transposons, General function prediction only];


The actual alignment was detected with superfamily member COG3501:

Pssm-ID: 442724 [Multi-domain]  Cd Length: 743  Bit Score: 67.09  E-value: 1.49e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2246628406   1 MSSEGLRFTLSVDGIVEMAT-AVVSFRLYQHHCTPFILDVDIASGLSDLTAEDFLEKSAVLTVWQGDTAQRYVSGIVTEV 79
Cdd:COG3501     1 MSLSQSNRLLTLETPLGDDAlLVLRFSGEEALSRPFEFELELLSEDADLDLDALLGKPATLTLRTADGPERYFHGIVTEF 80

                          90
                  ....*....|....
gi 2246628406  80 QLGENNDWQMRYSL 93
Cdd:COG3501    81 EQLGTDGGLARYRL 94
 
Name Accession Description Interval E-value
VgrG COG3501
Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly ...
 1-93 1.49e-14

Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly [Intracellular trafficking, secretion, and vesicular transport, Mobilome: prophages, transposons, General function prediction only];


Pssm-ID: 442724 [Multi-domain]  Cd Length: 743  Bit Score: 67.09  E-value: 1.49e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2246628406   1 MSSEGLRFTLSVDGIVEMAT-AVVSFRLYQHHCTPFILDVDIASGLSDLTAEDFLEKSAVLTVWQGDTAQRYVSGIVTEV 79
Cdd:COG3501     1 MSLSQSNRLLTLETPLGDDAlLVLRFSGEEALSRPFEFELELLSEDADLDLDALLGKPATLTLRTADGPERYFHGIVTEF 80

                          90
                  ....*....|....
gi 2246628406  80 QLGENNDWQMRYSL 93
Cdd:COG3501    81 EQLGTDGGLARYRL 94
VI_Rhs_Vgr TIGR03361
type VI secretion system Vgr family protein; Members of this protein family belong to the Rhs ...
 8-93 9.11e-13

type VI secretion system Vgr family protein; Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.


Pssm-ID: 274542 [Multi-domain]  Cd Length: 513  Bit Score: 61.83  E-value: 9.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2246628406   8 FTLSVDGiVEMATAVVSFRLYQHHCTPFILDVDIASGLSDLTAEDFLEKSAVLTVWQGDTAQRYVSGIVTEVQLGENNDW 87
Cdd:TIGR03361   1 FTLSTPL-GPDALQVLSFSGDEALSRLFSFRLELVSADPDIDLEDLLGQPATLTLGRDGGGPRYFHGIVTRFEQGGTGRR 79


                  ....*.
gi 2246628406  88 QMRYSL 93
Cdd:TIGR03361  80 LTRYRL 85
Phage_GPD pfam05954
Phage tail baseplate hub (GPD); This family includes a number of phage late expression gene D ...
 32-94 5.69e-09

Phage tail baseplate hub (GPD); This family includes a number of phage late expression gene D proteins and related bacterial sequences. This family also includes Bacteriophage Mu P proteins and related sequences. This protein forms the phage central baseplate hub.


Pssm-ID: 428689  Cd Length: 302  Bit Score: 51.16  E-value: 5.69e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2246628406  32 CTPFILDVDIASGLSDLTAEDFLEKSAVLTVWQGDTAQRYVSGIVTEVQLGENNDWQMRYSLS 94
Cdd:pfam05954   3 SRLFEFELTLLSDDPDIDLKALLGQPVTVSIELDGGGPRYFHGIVTEFEQVGSDGRLTRYRLT 65
 
Name Accession Description Interval E-value
VgrG COG3501
Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly ...
 1-93 1.49e-14

Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly [Intracellular trafficking, secretion, and vesicular transport, Mobilome: prophages, transposons, General function prediction only];


Pssm-ID: 442724 [Multi-domain]  Cd Length: 743  Bit Score: 67.09  E-value: 1.49e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2246628406   1 MSSEGLRFTLSVDGIVEMAT-AVVSFRLYQHHCTPFILDVDIASGLSDLTAEDFLEKSAVLTVWQGDTAQRYVSGIVTEV 79
Cdd:COG3501     1 MSLSQSNRLLTLETPLGDDAlLVLRFSGEEALSRPFEFELELLSEDADLDLDALLGKPATLTLRTADGPERYFHGIVTEF 80

                          90
                  ....*....|....
gi 2246628406  80 QLGENNDWQMRYSL 93
Cdd:COG3501    81 EQLGTDGGLARYRL 94
VI_Rhs_Vgr TIGR03361
type VI secretion system Vgr family protein; Members of this protein family belong to the Rhs ...
 8-93 9.11e-13

type VI secretion system Vgr family protein; Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.


Pssm-ID: 274542 [Multi-domain]  Cd Length: 513  Bit Score: 61.83  E-value: 9.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2246628406   8 FTLSVDGiVEMATAVVSFRLYQHHCTPFILDVDIASGLSDLTAEDFLEKSAVLTVWQGDTAQRYVSGIVTEVQLGENNDW 87
Cdd:TIGR03361   1 FTLSTPL-GPDALQVLSFSGDEALSRLFSFRLELVSADPDIDLEDLLGQPATLTLGRDGGGPRYFHGIVTRFEQGGTGRR 79


                  ....*.
gi 2246628406  88 QMRYSL 93
Cdd:TIGR03361  80 LTRYRL 85
Phage_GPD pfam05954
Phage tail baseplate hub (GPD); This family includes a number of phage late expression gene D ...
 32-94 5.69e-09

Phage tail baseplate hub (GPD); This family includes a number of phage late expression gene D proteins and related bacterial sequences. This family also includes Bacteriophage Mu P proteins and related sequences. This protein forms the phage central baseplate hub.


Pssm-ID: 428689  Cd Length: 302  Bit Score: 51.16  E-value: 5.69e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2246628406  32 CTPFILDVDIASGLSDLTAEDFLEKSAVLTVWQGDTAQRYVSGIVTEVQLGENNDWQMRYSLS 94
Cdd:pfam05954   3 SRLFEFELTLLSDDPDIDLKALLGQPVTVSIELDGGGPRYFHGIVTEFEQVGSDGRLTRYRLT 65
vgr_GE TIGR01646
Rhs element Vgr protein; This model represents the Vgr family of proteins, associated with ...
 21-94 4.94e-05

Rhs element Vgr protein; This model represents the Vgr family of proteins, associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region, VGXXXXXX, found in the Vgr of Rhs classes G and E.


Pssm-ID: 273730 [Multi-domain]  Cd Length: 483  Bit Score: 40.15  E-value: 4.94e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2246628406  21 AVVSFRLYQHHCTPFILDVDIASGLSDLTAEDFLEKSAVLTVWQGDTA--QRYVSGIVTEVQLGENNDWQMRYSLS 94
Cdd:TIGR01646   2 TVLSFEGNEILSQPFTYELILRSADADLDLAAMLGKDASLSLELPDAAstQRIFTGVIAGFSLGSTANGDARYSLV 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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