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Conserved domains on  [gi|2255892240|ref|WP_251889592|]
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MULTISPECIES: FAD-binding oxidoreductase [Klebsiella]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11429741)

FAD/NAD(P)-binding oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.30.9.10
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660
SCOP:  3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
2-361 1.86e-77

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


:

Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 242.50  E-value: 1.86e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   2 KQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQP--GATAAGMGHLVC---MDDDPAELALSAWSLERWRAITPRMPD 76
Cdd:COG0665     1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPgsGASGRNAGQLRPglaALADRALVRLAREALDLWRELAAELGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  77 NCAWRGCGTLWLAESEEEMTVADEKQRRMAGHQVHSERQTPQQIAGREPLLRGGLAGG-LWVPGDGIVYAPNVARWLIAD 155
Cdd:COG0665    81 DCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGgLYDPDDGHVDPAKLVRALARA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 156 AGDH-LTCLRDS-VQTI----DEPQVLLASGQRLQARAIVVACGLEANALLAEN----WLRPKKGQLAITDRYRPRVQHQ 225
Cdd:COG0665   161 ARAAgVRIREGTpVTGLeregGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLglrlPLRPVRGYVLVTEPLPDLPLRP 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 226 LVelgygasahgggTSVAFNLQPRPTGQLLIGSSRQFDNRERELDLPLLAQMLDRARHFVPELATLNIIRCWSGLRAASQ 305
Cdd:COG0665   241 VL------------DDTGVYLRPTADGRLLVGGTAEPAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTP 308

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2255892240 306 DGNPLIGPHPARRGVWLALGHEGLGVTTAPATAELLAAQILDERSPLAPDAWLPVR 361
Cdd:COG0665   309 DGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
2-361 1.86e-77

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 242.50  E-value: 1.86e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   2 KQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQP--GATAAGMGHLVC---MDDDPAELALSAWSLERWRAITPRMPD 76
Cdd:COG0665     1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPgsGASGRNAGQLRPglaALADRALVRLAREALDLWRELAAELGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  77 NCAWRGCGTLWLAESEEEMTVADEKQRRMAGHQVHSERQTPQQIAGREPLLRGGLAGG-LWVPGDGIVYAPNVARWLIAD 155
Cdd:COG0665    81 DCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGgLYDPDDGHVDPAKLVRALARA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 156 AGDH-LTCLRDS-VQTI----DEPQVLLASGQRLQARAIVVACGLEANALLAEN----WLRPKKGQLAITDRYRPRVQHQ 225
Cdd:COG0665   161 ARAAgVRIREGTpVTGLeregGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLglrlPLRPVRGYVLVTEPLPDLPLRP 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 226 LVelgygasahgggTSVAFNLQPRPTGQLLIGSSRQFDNRERELDLPLLAQMLDRARHFVPELATLNIIRCWSGLRAASQ 305
Cdd:COG0665   241 VL------------DDTGVYLRPTADGRLLVGGTAEPAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTP 308

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2255892240 306 DGNPLIGPHPARRGVWLALGHEGLGVTTAPATAELLAAQILDERSPLAPDAWLPVR 361
Cdd:COG0665   309 DGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 5-344 2.75e-52

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 176.82  E-value: 2.75e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLID------NGQPGATAAGMGHLVCMDDDPAELALSAWSLERWRAITPRMPDNC 78
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLErgddpgSGASGRNAGLIHPGLRYLEPSELARLALEALDLWEELEEELGIDC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  79 AWRGCGTLWLAESEEEmTVADEKQRRMAGHQVHSERQTPQQIAGREPlLRGGLAGGLWVPGDGIVYAPNVARWLIADAGD 158
Cdd:pfam01266  81 GFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEP-LLPGLRGGLFYPDGGHVDPARLLRALARAAEA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 159 H-LTCLRDS-VQTIDEPQVLLASGQRLQARAIVVACGLEANALLAENW---LRPKKGQLAITdryRPRVQHQLVELGYGA 233
Cdd:pfam01266 159 LgVRIIEGTeVTGIEEEGGVWGVVTTGEADAVVNAAGAWADLLALPGLrlpVRPVRGQVLVL---EPLPEALLILPVPIT 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 234 SAHGGGTSVAfnlqPRPTGQLLIGSSRQFDNRER-ELDLPLLAQMLDRARHFVPELAtlNIIRCWSGLRAASqDGNPLIG 312
Cdd:pfam01266 236 VDPGRGVYLR----PRADGRLLLGGTDEEDGFDDpTPDPEEIEELLEAARRLFPALA--DIERAWAGLRPLP-DGLPIIG 308

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2255892240 313 PHPArRGVWLALGHEGLGVTTAPATAELLAAQ 344
Cdd:pfam01266 309 RPGS-PGLYLATGHGGHGLTLAPGIGKLLAEL 339
MnmC_Cterm TIGR03197
tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain; In ...
 18-357 6.11e-25

tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain; In Escherichia coli, the protein previously designated YfcK is now identified as the bifunctional enzyme MnmC. It acts, following the action of the heterotetramer of GidA and MnmE, in the modification of U-34 of certain tRNA to 5-methylaminomethyl-2-thiouridine (mnm5s2U). In other bacterial, the corresponding proteins are usually but always found as a single polypeptide chain, but occasionally as the product of tandem genes. This model represents the C-terminal region of the multifunctional protein. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 274478 [Multi-domain]  Cd Length: 381  Bit Score: 104.27  E-value: 6.11e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  18 CAWQLAKRGQSVTLID-NGQPGATAAG-----MGHLVCMDDDP-AELALSAW--SLERWRAITPRMPDNcAWRGCGTLWL 88
Cdd:TIGR03197   1 TAYSLARRGWQVTLYEqDEAPAQGASGnpqgaLYPLLSADDNPlSRFFLAAFlyARRFYRQLAEAGFPF-DHEWCGVLQL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  89 AESEEEMtvadEKQRRMAGHQVHSE-------RQTPQQIAGrepllRGGLAGGLWVPGDGIVYAPNVARWLIADAGDHLT 161
Cdd:TIGR03197  80 AYDEKEA----ERLQKLLEQLGFPEelarwvdAEQASQLAG-----IPLPYGGLFFPQGGWLSPPQLCRALLAHAGIRLT 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 162 CLRDS-----VQTIDEPQVLLASGQRLQARAIVVACGLEANALLAENWL--RPKKGQLAI--TDRYRPRVQHQLVELGYg 232
Cdd:TIGR03197 151 LHFNTeitslERDGEGWQLLDANGEVIAASVVVLANGAQAPQLAQTAHLplRPVRGQVSHlpATEALSALKTVLCYDGY- 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 233 asahgggtsvafnLQPRPTGQLLIGSSRQFDNRERELDLPLLAQMLDRARHFVPELATLN-----IIRCWSGLRAASQDG 307
Cdd:TIGR03197 230 -------------LTPANNGEHCIGASYDRNDDDLALREADHAENLERLAECLPALAWASevdisALQGRVGVRCASPDH 296

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2255892240 308 NPLIGP---------------HPARR----------GVWLALGHEGLGVTTAPATAELLAAQILDERSPLAPDAW 357
Cdd:TIGR03197 297 LPLVGAvpdfeaikeayaelaKDKNRpiaepapyypGLYVLGGLGSRGLTSAPLAAEILAAQICGEPLPLERDLL 371
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 5-352 8.39e-21

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 93.76  E-value: 8.39e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLID-NGQPGATA----AGMGHLVCMDDDPA--ELALSA--WSLERWRAITPRMP 75
Cdd:PRK01747  262 DAAIIGGGIAGAALALALARRGWQVTLYEaDEAPAQGAsgnrQGALYPLLSKDDNAlsRFFRAAflFARRFYDALPAAGV 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  76 DNcAWRGCGTLWLAESEEEmtvaDEKQRRMAGHQVHSE------RQTPQQIAGrepllRGGLAGGLWVPGDGIVYAPNVA 149
Cdd:PRK01747  342 AF-DHDWCGVLQLAWDEKS----AEKIAKMLALGLPAElaraldAEEAEELAG-----LPVPCGGIFYPQGGWLCPAELC 411

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 150 RWLIADAGDHLTCLRDS-----VQTIDEPQVLLASGQRLQARAIVVACGLEANAL--LAENWLRPKKGQ---LAITDRYR 219
Cdd:PRK01747  412 RALLALAGQQLTIHFGHevarlEREDDGWQLDFAGGTLASAPVVVLANGHDAARFaqTAHLPLYSVRGQvshLPTTPALS 491

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 220 PRVQhQLVELGYgasahgggtsvafnLQPRPTGQL-LIGSSRQFDNRERELDLPLLAQMLDRARHFVPELATLNII---- 294
Cdd:PRK01747  492 ALKQ-VLCYDGY--------------LTPQPANGThCIGASYDRDDTDTAFREADHQENLERLAECLPQALWAKEVdvsa 556

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 295 ---RCwsGLRAASQDGNPLIGP---------------HPARR-------GVWLALGHEGLGVTTAPATAELLAAQILDER 349
Cdd:PRK01747  557 lqgRV--GFRCASRDRLPMVGNvpdeaatlaeyaalaNQQPArdaprlpGLYVAGALGSRGLCSAPLGAELLASQIEGEP 634


                  ...
gi 2255892240 350 SPL 352
Cdd:PRK01747  635 LPL 637
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
2-361 1.86e-77

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 242.50  E-value: 1.86e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   2 KQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQP--GATAAGMGHLVC---MDDDPAELALSAWSLERWRAITPRMPD 76
Cdd:COG0665     1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPgsGASGRNAGQLRPglaALADRALVRLAREALDLWRELAAELGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  77 NCAWRGCGTLWLAESEEEMTVADEKQRRMAGHQVHSERQTPQQIAGREPLLRGGLAGG-LWVPGDGIVYAPNVARWLIAD 155
Cdd:COG0665    81 DCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGgLYDPDDGHVDPAKLVRALARA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 156 AGDH-LTCLRDS-VQTI----DEPQVLLASGQRLQARAIVVACGLEANALLAEN----WLRPKKGQLAITDRYRPRVQHQ 225
Cdd:COG0665   161 ARAAgVRIREGTpVTGLeregGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLglrlPLRPVRGYVLVTEPLPDLPLRP 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 226 LVelgygasahgggTSVAFNLQPRPTGQLLIGSSRQFDNRERELDLPLLAQMLDRARHFVPELATLNIIRCWSGLRAASQ 305
Cdd:COG0665   241 VL------------DDTGVYLRPTADGRLLVGGTAEPAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTP 308

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2255892240 306 DGNPLIGPHPARRGVWLALGHEGLGVTTAPATAELLAAQILDERSPLAPDAWLPVR 361
Cdd:COG0665   309 DGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 5-344 2.75e-52

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 176.82  E-value: 2.75e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLID------NGQPGATAAGMGHLVCMDDDPAELALSAWSLERWRAITPRMPDNC 78
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLErgddpgSGASGRNAGLIHPGLRYLEPSELARLALEALDLWEELEEELGIDC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  79 AWRGCGTLWLAESEEEmTVADEKQRRMAGHQVHSERQTPQQIAGREPlLRGGLAGGLWVPGDGIVYAPNVARWLIADAGD 158
Cdd:pfam01266  81 GFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEP-LLPGLRGGLFYPDGGHVDPARLLRALARAAEA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 159 H-LTCLRDS-VQTIDEPQVLLASGQRLQARAIVVACGLEANALLAENW---LRPKKGQLAITdryRPRVQHQLVELGYGA 233
Cdd:pfam01266 159 LgVRIIEGTeVTGIEEEGGVWGVVTTGEADAVVNAAGAWADLLALPGLrlpVRPVRGQVLVL---EPLPEALLILPVPIT 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 234 SAHGGGTSVAfnlqPRPTGQLLIGSSRQFDNRER-ELDLPLLAQMLDRARHFVPELAtlNIIRCWSGLRAASqDGNPLIG 312
Cdd:pfam01266 236 VDPGRGVYLR----PRADGRLLLGGTDEEDGFDDpTPDPEEIEELLEAARRLFPALA--DIERAWAGLRPLP-DGLPIIG 308

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2255892240 313 PHPArRGVWLALGHEGLGVTTAPATAELLAAQ 344
Cdd:pfam01266 309 RPGS-PGLYLATGHGGHGLTLAPGIGKLLAEL 339
MnmC_Cterm TIGR03197
tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain; In ...
 18-357 6.11e-25

tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain; In Escherichia coli, the protein previously designated YfcK is now identified as the bifunctional enzyme MnmC. It acts, following the action of the heterotetramer of GidA and MnmE, in the modification of U-34 of certain tRNA to 5-methylaminomethyl-2-thiouridine (mnm5s2U). In other bacterial, the corresponding proteins are usually but always found as a single polypeptide chain, but occasionally as the product of tandem genes. This model represents the C-terminal region of the multifunctional protein. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 274478 [Multi-domain]  Cd Length: 381  Bit Score: 104.27  E-value: 6.11e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  18 CAWQLAKRGQSVTLID-NGQPGATAAG-----MGHLVCMDDDP-AELALSAW--SLERWRAITPRMPDNcAWRGCGTLWL 88
Cdd:TIGR03197   1 TAYSLARRGWQVTLYEqDEAPAQGASGnpqgaLYPLLSADDNPlSRFFLAAFlyARRFYRQLAEAGFPF-DHEWCGVLQL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  89 AESEEEMtvadEKQRRMAGHQVHSE-------RQTPQQIAGrepllRGGLAGGLWVPGDGIVYAPNVARWLIADAGDHLT 161
Cdd:TIGR03197  80 AYDEKEA----ERLQKLLEQLGFPEelarwvdAEQASQLAG-----IPLPYGGLFFPQGGWLSPPQLCRALLAHAGIRLT 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 162 CLRDS-----VQTIDEPQVLLASGQRLQARAIVVACGLEANALLAENWL--RPKKGQLAI--TDRYRPRVQHQLVELGYg 232
Cdd:TIGR03197 151 LHFNTeitslERDGEGWQLLDANGEVIAASVVVLANGAQAPQLAQTAHLplRPVRGQVSHlpATEALSALKTVLCYDGY- 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 233 asahgggtsvafnLQPRPTGQLLIGSSRQFDNRERELDLPLLAQMLDRARHFVPELATLN-----IIRCWSGLRAASQDG 307
Cdd:TIGR03197 230 -------------LTPANNGEHCIGASYDRNDDDLALREADHAENLERLAECLPALAWASevdisALQGRVGVRCASPDH 296

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2255892240 308 NPLIGP---------------HPARR----------GVWLALGHEGLGVTTAPATAELLAAQILDERSPLAPDAW 357
Cdd:TIGR03197 297 LPLVGAvpdfeaikeayaelaKDKNRpiaepapyypGLYVLGGLGSRGLTSAPLAAEILAAQICGEPLPLERDLL 371
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
1-361 7.98e-25

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 104.46  E-value: 7.98e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKR-GQSVTLID-NGQPGATA----AGMGHlVCMDDDP----AELA------LSAWSL 64
Cdd:COG0579     2 MEMYDVVIIGAGIVGLALARELSRYeDLKVLVLEkEDDVAQESsgnnSGVIH-AGLYYTPgslkARLCvegnelFYELCR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  65 ERwraitprmpdNCAWRGCGTLWLAESEEEMTVADEKQRRMAGHQVHS-ERQTPQQIAGREPLLRGGLAGGLWVPGDGIV 143
Cdd:COG0579    81 EL----------GIPFKRCGKLVVATGEEEVAFLEKLYERGKANGVPGlEILDREELRELEPLLSDEGVAALYSPSTGIV 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 144 YAPNVARWLIADAGDH-LTCLRDS-VQTIDEPQ---VLLASGQRLQARAIVVACGLEANALLA----ENWLR--PKKGQL 212
Cdd:COG0579   151 DPGALTRALAENAEANgVELLLNTeVTGIEREGdgwEVTTNGGTIRARFVINAAGLYADRLAQmagiGKDFGifPVKGEY 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 213 AITDRYRPRVQHqLVelgYG-ASAHGGGTSVAFNlqPRPTGQLLIG-----------------SSRQFDNRERELDLPLL 274
Cdd:COG0579   231 LVLDKPAELVNA-KV---YPvPDPGAPFLGVHLT--RTIDGNLLFGpnavfvpkkedslldlfESLRFPNFWPMLAKNLL 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 275 ------------AQMLDRARHFVPELATLNIIRCWSGLRAA--SQDGNPLIGPHPARRGVWLALGhEGLGVTTAPATAEL 340
Cdd:COG0579   305 tkylesvtslskEAFLEALRKYVPELPDEDLIPAFAGIRAQiiKPDGDFVIEEADDPGSIHVLGI-ESPGATSALAIAEH 383

                         410       420
                  ....*....|....*....|.
gi 2255892240 341 LAAQILDErspLAPDAWLPVR 361
Cdd:COG0579   384 VAELLPEK---LEEKDWQPKR 401
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 5-352 8.39e-21

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 93.76  E-value: 8.39e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLID-NGQPGATA----AGMGHLVCMDDDPA--ELALSA--WSLERWRAITPRMP 75
Cdd:PRK01747  262 DAAIIGGGIAGAALALALARRGWQVTLYEaDEAPAQGAsgnrQGALYPLLSKDDNAlsRFFRAAflFARRFYDALPAAGV 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  76 DNcAWRGCGTLWLAESEEEmtvaDEKQRRMAGHQVHSE------RQTPQQIAGrepllRGGLAGGLWVPGDGIVYAPNVA 149
Cdd:PRK01747  342 AF-DHDWCGVLQLAWDEKS----AEKIAKMLALGLPAElaraldAEEAEELAG-----LPVPCGGIFYPQGGWLCPAELC 411

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 150 RWLIADAGDHLTCLRDS-----VQTIDEPQVLLASGQRLQARAIVVACGLEANAL--LAENWLRPKKGQ---LAITDRYR 219
Cdd:PRK01747  412 RALLALAGQQLTIHFGHevarlEREDDGWQLDFAGGTLASAPVVVLANGHDAARFaqTAHLPLYSVRGQvshLPTTPALS 491

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 220 PRVQhQLVELGYgasahgggtsvafnLQPRPTGQL-LIGSSRQFDNRERELDLPLLAQMLDRARHFVPELATLNII---- 294
Cdd:PRK01747  492 ALKQ-VLCYDGY--------------LTPQPANGThCIGASYDRDDTDTAFREADHQENLERLAECLPQALWAKEVdvsa 556

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240 295 ---RCwsGLRAASQDGNPLIGP---------------HPARR-------GVWLALGHEGLGVTTAPATAELLAAQILDER 349
Cdd:PRK01747  557 lqgRV--GFRCASRDRLPMVGNvpdeaatlaeyaalaNQQPArdaprlpGLYVAGALGSRGLCSAPLGAELLASQIEGEP 634


                  ...
gi 2255892240 350 SPL 352
Cdd:PRK01747  635 LPL 637
PRK00711 PRK00711
D-amino acid dehydrogenase;
297-355 1.97e-07

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 52.49  E-value: 1.97e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2255892240 297 WSGLRAASQDGNPLIGPHPArRGVWLALGHEGLGVTTAPATAELLAAQILDERSPLAPD 355
Cdd:PRK00711  352 WTGLRPMTPDGTPIVGATRY-KNLWLNTGHGTLGWTMACGSGQLLADLISGRKPAIDAD 409
solA PRK11259
N-methyl-L-tryptophan oxidase;
1-37 8.32e-07

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 50.22  E-value: 8.32e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQP 37
Cdd:PRK11259    1 TMRYDVIVIGLGSMGSAAGYYLARRGLRVLGLDRFMP 37
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 1-50 1.89e-06

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 49.41  E-value: 1.89e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQPGATAAGMGhlvCM 50
Cdd:PRK06292    1 MEKYDVIVIGAGPAGYVAARRAAKLGKKVALIEKGPLGGTCLNVG---CI 47
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 1-40 8.44e-06

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 47.39  E-value: 8.44e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQPGAT 40
Cdd:COG1249     1 MKDYDLVVIGAGPGGYVAAIRAAQLGLKVALVEKGRLGGT 40
GlpB COG3075
Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];
3-36 1.03e-05

Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];


Pssm-ID: 442309  Cd Length: 415  Bit Score: 47.10  E-value: 1.03e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2255892240   3 QCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQ 36
Cdd:COG3075     2 KFDVVVIGGGLAGLTAAIRAAEAGLRVAIVSAGQ 35
HI0933_like pfam03486
HI0933-like protein;
4-38 1.10e-05

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 46.81  E-value: 1.10e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2255892240   4 CDVIVIGAGIIGAACAWQLAKRGQSVTLIDNG-QPG 38
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKGkKLG 36
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 5-33 1.35e-05

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 46.75  E-value: 1.35e-05
                          10        20
                  ....*....|....*....|....*....
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLID 33
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGKKTLLLE 30
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
8-42 1.39e-05

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 42.52  E-value: 1.39e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2255892240   8 VIGAGIIGAACAWQLAKRGQSVTLIDNG-QPGATAA 42
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRdRLGGNAY 36
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
4-199 2.25e-05

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 45.97  E-value: 2.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   4 CDVIVIGAGIIGAACAWQLAKR--GQSVTLIDN-GQPGA--TA-------AGM----GHLvcmdddPAELAlsawslerw 67
Cdd:PRK11728    3 YDFVIIGGGIVGLSTAMQLQERypGARIAVLEKeSGPARhqTGhnsgvihAGVyytpGSL------KARFC--------- 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240  68 RAITPRMPDNCAWRG-----CGTLWLAESEEEMTVADEKQRRMAGHQVHSERQTPQQIAGREPLLRGGLAGglWVPGDGI 142
Cdd:PRK11728   68 RRGNEATKAFCDQHGipyeeCGKLLVATSELELERMEALYERARANGIEVERLDAEELREREPNIRGLGAI--FVPSTGI 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2255892240 143 VYAPNVARWL---IADAGDHLtCLRDSVQTIDEP---QVLLASGQRLQARAIVVACGLEANAL 199
Cdd:PRK11728  146 VDYRAVAEAMaelIQARGGEI-RLGAEVTALDEHangVVVRTTQGEYEARTLINCAGLMSDRL 207
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
1-33 2.74e-05

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 45.64  E-value: 2.74e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLID 33
Cdd:COG3380     1 MSMPDIAIIGAGIAGLAAARALQDAGHEVTVFE 33
PRK00711 PRK00711
D-amino acid dehydrogenase;
6-39 2.96e-05

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 45.56  E-value: 2.96e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2255892240   6 VIVIGAGIIGAACAWQLAKRGQSVTLIDNgQPGA 39
Cdd:PRK00711    3 VVVLGSGVIGVTSAWYLAQAGHEVTVIDR-QPGP 35
GIDA pfam01134
Glucose inhibited division protein A;
5-32 2.98e-05

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 45.62  E-value: 2.98e-05
                          10        20
                  ....*....|....*....|....*...
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLI 32
Cdd:pfam01134   1 DVIVIGGGHAGCEAALAAARMGAKVLLI 28
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 1-39 3.29e-05

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 45.53  E-value: 3.29e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQPGA 39
Cdd:PRK08849    1 MNKYDIAVVGGGMVGAATALGFAKQGRSVAVIEGGEPKA 39
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 5-45 4.24e-05

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 44.97  E-value: 4.24e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQP--GATAAGMG 45
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPfgGATAWSSG 43
TrmFO COG1206
Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and ...
 5-31 4.33e-05

Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and biogenesis]; Folate-dependent tRNA-U54 methylase TrmFO/GidA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440819  Cd Length: 436  Bit Score: 45.05  E-value: 4.33e-05
                          10        20
                  ....*....|....*....|....*..
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTL 31
Cdd:COG1206     3 PVTVIGGGLAGSEAAWQLAERGVPVRL 29
PRK05335 PRK05335
tRNA (uracil-5-)-methyltransferase Gid; Reviewed
 6-31 4.57e-05

tRNA (uracil-5-)-methyltransferase Gid; Reviewed


Pssm-ID: 235416  Cd Length: 436  Bit Score: 45.14  E-value: 4.57e-05
                          10        20
                  ....*....|....*....|....*.
gi 2255892240   6 VIVIGAGIIGAACAWQLAKRGQSVTL 31
Cdd:PRK05335    5 VNVIGAGLAGSEAAWQLAKRGVPVEL 30
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-38 5.50e-05

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 44.84  E-value: 5.50e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLID-NGQPG 38
Cdd:COG1233     1 MMMYDVVVIGAGIGGLAAAALLARAGYRVTVLEkNDTPG 39
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-70 8.48e-05

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 44.16  E-value: 8.48e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQPGATaagmghlvcmddDPAELALSAWSLERWRAI 70
Cdd:COG0654     1 MMRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRP------------DGRGIALSPRSLELLRRL 58
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
4-51 1.08e-04

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 44.07  E-value: 1.08e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2255892240   4 CDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQpGATAAGMGhlvCMD 51
Cdd:PRK05329    3 FDVLVIGGGLAGLTAALAAAEAGKRVALVAKGQ-GALHFSSG---SID 46
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-38 1.47e-04

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 43.67  E-value: 1.47e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2255892240   3 QCDVIVIGAGIIGAACAWQLAKRGQSVTLID-NGQPG 38
Cdd:COG1232     1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEaSDRVG 37
glycerol3P_GlpB TIGR03378
glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are ...
 5-36 2.20e-04

glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are the B subunit, product of the glpB gene, of a three-subunit, membrane-anchored, FAD-dependent anaerobic glycerol-3-phosphate dehydrogenase. [Energy metabolism, Anaerobic]


Pssm-ID: 213807  Cd Length: 419  Bit Score: 43.08  E-value: 2.20e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQ 36
Cdd:TIGR03378   2 DVIIIGGGLAGLSCALRLAEAGKKCAIIAAGQ 33
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 6-33 3.71e-04

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 42.32  E-value: 3.71e-04
                          10        20
                  ....*....|....*....|....*...
gi 2255892240   6 VIVIGAGIIGAACAWQLAKRGQSVTLID 33
Cdd:PRK12409    4 IAVIGAGITGVTTAYALAQRGYQVTVFD 31
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
1-32 4.06e-04

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 42.22  E-value: 4.06e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLI 32
Cdd:COG1231     5 ARGKDVVIVGAGLAGLAAARELRKAGLDVTVL 36
PRK07121 PRK07121
FAD-binding protein;
4-46 1.08e-03

FAD-binding protein;


Pssm-ID: 180854 [Multi-domain]  Cd Length: 492  Bit Score: 41.03  E-value: 1.08e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2255892240   4 CDVIVIGAGIIGAACAWQLAKRGQSVTLID--NGQPGATAAGMGH 46
Cdd:PRK07121   21 ADVVVVGFGAAGACAAIEAAAAGARVLVLEraAGAGGATALSGGV 65
PRK07233 PRK07233
hypothetical protein; Provisional
 6-56 1.11e-03

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 40.64  E-value: 1.11e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2255892240   6 VIVIGAGIIGAACAWQLAKRGQSVTLID-NGQPGataaGMGHLVCMDDDPAE 56
Cdd:PRK07233    2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEaDDQLG----GLAASFEFGGLPIE 49
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 1-32 1.15e-03

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 40.86  E-value: 1.15e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQsVTLI 32
Cdd:COG0029     2 RLKTDVLVIGSGIAGLSAALKLAERGR-VTLL 32
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
3-33 1.30e-03

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 40.55  E-value: 1.30e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2255892240   3 QCDVIVIGAGIIGAACAWQLAKRGQSVTLID 33
Cdd:COG3573     5 DADVIVVGAGLAGLVAAAELADAGRRVLLLD 35
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 6-44 1.30e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 40.63  E-value: 1.30e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2255892240   6 VIVIGAGIIGAACAWQLAKRGQSVTLIDNG-QPGataaGM 44
Cdd:PRK12771  140 VAVIGGGPAGLSAAYHLRRMGHAVTIFEAGpKLG----GM 175
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-38 2.54e-03

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 39.45  E-value: 2.54e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLID-NGQPG 38
Cdd:COG3349     1 MMPPRVVVVGGGLAGLAAAVELAEAGFRVTLLEaRPRLG 39
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 1-33 2.59e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.22  E-value: 2.59e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLID 33
Cdd:pfam07992 150 LLPKRVVVVGGGYIGVELAAALAKLGKEVTLIE 182
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 1-58 2.96e-03

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 39.43  E-value: 2.96e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQP--GATAAGMGHLVCMDDDPAELA 58
Cdd:COG1053     1 DHEYDVVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPrgGHTAAAQGGINAAGTNVQKAA 60
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-40 3.39e-03

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 39.08  E-value: 3.39e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLID-NGQPGAT 40
Cdd:COG2072     4 TEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEkADDVGGT 44
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 6-33 4.18e-03

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 38.99  E-value: 4.18e-03
                          10        20
                  ....*....|....*....|....*...
gi 2255892240   6 VIVIGAGIIGAACAWQLAKRGQSVTLID 33
Cdd:PRK12810  146 VAVVGSGPAGLAAADQLARAGHKVTVFE 173
PRK09126 PRK09126
FAD-dependent hydroxylase;
1-72 4.36e-03

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 38.77  E-value: 4.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLIDnGQPGATAAgmghlvcmddDPA----ELAL---SAWSLER---WRAI 70
Cdd:PRK09126    1 MMHSDIVVVGAGPAGLSFARSLAGSGLKVTLIE-RQPLAALA----------DPAfdgrEIALthaSREILQRlgaWDRI 69


                  ..
gi 2255892240  71 TP 72
Cdd:PRK09126   70 PE 71
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 6-35 5.02e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 35.64  E-value: 5.02e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 2255892240   6 VIVIGAGIIGAACAWQLAKRGQSVTLIDNG 35
Cdd:pfam00070   2 VVVVGGGYIGLELAGALARLGSKVTVVERR 31
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 282-345 6.14e-03

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 38.47  E-value: 6.14e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2255892240 282 RHFvPELATLNIIRcWSGLRAASQDGNPLIGPHpARRGVWLALGHEGLGVTTAPATAELLAAQI 345
Cdd:PRK12409  343 RNF-PDVSTRRVVP-WAGLRPMMPNMMPRVGRG-RRPGVFYNTGHGHLGWTLSAATADLVAQVV 403
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 5-40 6.18e-03

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 38.59  E-value: 6.18e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQPGAT 40
Cdd:PRK06416    6 DVIVIGAGPGGYVAAIRAAQLGLKVAIVEKEKLGGT 41
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
5-41 6.39e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 38.40  E-value: 6.39e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQPGATA 41
Cdd:PRK07608    7 DVVVVGGGLVGASLALALAQSGLRVALLAPRAPPRPA 43
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 5-77 6.72e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 38.07  E-value: 6.72e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLID------NGQPGATAAgmghLVCMDDDPAELALSAWSLERWRAITPRMPDN 77
Cdd:pfam07992   2 DVVVIGGGPAGLAAALTLAQLGGKVTLIEdegtcpYGGCVLSKA----LLGAAEAPEIASLWADLYKRKEEVVKKLNNG 76
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 1-33 6.81e-03

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 38.34  E-value: 6.81e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLID 33
Cdd:PRK12834    2 AMDADVIVVGAGLAGLVAAAELADAGKRVLLLD 34
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
4-38 7.00e-03

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 37.79  E-value: 7.00e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2255892240   4 CDVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQPG 38
Cdd:COG0492     1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIEGGEPG 35
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
5-37 7.19e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 38.30  E-value: 7.19e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQP 37
Cdd:PRK08773    8 DAVIVGGGVVGAACALALADAGLSVALVEGREP 40
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
1-33 7.29e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 37.96  E-value: 7.29e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2255892240   1 MKQCDVIVIGAGIIGAACAWQLAKRGQSVTLID 33
Cdd:PRK07494    5 KEHTDIAVIGGGPAGLAAAIALARAGASVALVA 37
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 5-43 9.01e-03

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 37.66  E-value: 9.01e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2255892240   5 DVIVIGAGIIGAACAWQLAKRGQSVTLIDNGQPGATAAG 43
Cdd:PRK08020    7 DIAIVGGGMVGAALALGLAQHGFSVAVLEHAAPAPFDAD 45
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 6-34 9.53e-03

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 37.35  E-value: 9.53e-03
                          10        20
                  ....*....|....*....|....*....
gi 2255892240   6 VIVIGAGIIGAACAWQLAKRGQSVTLIDN 34
Cdd:COG0569    98 VIIIGAGRVGRSLARELEEEGHDVVVIDK 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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