|
Name |
Accession |
Description |
Interval |
E-value |
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
10-462 |
0e+00 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 681.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 10 LGRIRQVHMVGIGGIGMSSIAEVLLNRGYTVTGSDLERSDVTERLEAQGATIHEGHAAEQVGTADVVVYSSAVDPDeNPE 89
Cdd:COG0773 1 LDKIMHIHFIGIGGIGMSGLAEILLALGYKVSGSDLAESPMTERLEALGIPVFIGHDAENIDDADLVVVSSAIPRD-NPE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 90 TREAERRRISLIPRAEMLGELIRMKFGVGVAGTHGKTTTTSMAGLVVAEGGFDPTVIVGGKVTAFGSNAITGEGDVLVIE 169
Cdd:COG0773 80 LVAARERGIPVLSRAEMLAELMRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFGTNARLGDGDYFVAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 170 ADEYDRTFLRLTPSLAVITSIEEDHLDVYEDLAAIQAAFTQYANSVPFFGAAILCLDDPNVQAIVGDVERRVVTYGTTRQ 249
Cdd:COG0773 160 ADESDGSFLHYSPDIAVVTNIEADHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPRCGRPVITYGFSED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 250 AEVRGENVRREGMTTRFDVVVRGERLGTIELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRFEKKGEVG 329
Cdd:COG0773 240 ADYRAENIRIDGGGSTFDVLRRGEELGEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRRFELKGEVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 330 GITVLDDYAHHPTEIEATLDAAHQGFPDRRVVAVFQPHMYSRTQNFMDEFARSFFNADMLVLTDVYGAREAPIEGVTGGR 409
Cdd:COG0773 320 GVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYSRTRDFLDEFAEALSLADEVILLDIYAAREKPIPGVSSED 399
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 2255965446 410 LAERAEQFGHRaVHYVPEKTDLPGRLQELVGPGDVVLMLGAGDIWRASEAFVE 462
Cdd:COG0773 400 LAEAIRKRGKD-VVYVPDLDELVEALAEIARPGDVVLTMGAGDIGGLGEKLLE 451
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
15-461 |
0e+00 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 546.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 15 QVHMVGIGGIGMSSIAEVLLNRGYTVTGSDLERSDVTERLEAQGATIHEGHAAEQVGTADVVVYSSAVdPDENPETREAE 94
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENATTKRLEALGIPIYIGHSAENLDDADVVVVSAAI-KDDNPEIVEAK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 95 RRRISLIPRAEMLGELIRMKFGVGVAGTHGKTTTTSMAGLVVAEGGFDPTVIVGGKVTAFGSNAITGEGDVLVIEADEYD 174
Cdd:TIGR01082 80 ERGIPVIRRAEMLAELMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAGTNARLGSGEYLVAEADESD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 175 RTFLRLTPSLAVITSIEEDHLDVYE-DLAAIQAAFTQYANSVPFFGAAILCLDDPNVQAIVGDVERRVVTYGTTR-QAEV 252
Cdd:TIGR01082 160 ASFLHLQPNVAIVTNIEPDHLDTYGsSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELVPKATEQVITYGGSGeDADY 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 253 RGENVRREGMTTRFDVVVRGERLGTIELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRFEKKGEVGGIT 332
Cdd:TIGR01082 240 RAENIQQSGAEGKFSVRGKGKLYLEFTLNLPGRHNVLNALAAIAVALELGIDFEAILRALANFQGVKRRFEILGEFGGVL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 333 VLDDYAHHPTEIEATLDAAHQGFPDRRVVAVFQPHMYSRTQNFMDEFARSFFNADMLVLTDVYGAREAPIEGVTGGRLAE 412
Cdd:TIGR01082 320 LIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHRYSRTRDLFDDFAKVLSDADELILLDIYAAGEEPINGIDGKSLAR 399
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 2255965446 413 RAEQFGHRAVHYVPEKTDLPGRLQELVGPGDVVLMLGAGDIWRASEAFV 461
Cdd:TIGR01082 400 KITQLGKIEPYFVPDLAELVEFLAAVLQSGDLILTMGAGDIIKLARELL 448
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
15-459 |
2.87e-99 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 315.60 E-value: 2.87e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 15 QVHMVGIGGIGMSSIAEVLLNRGYTVTGSDLERSDVTERLEAQGATIHEGHAAEQVGTADVVVYSSAVDPDeNPETREAE 94
Cdd:PRK14573 6 FYHFIGIGGIGMSALAHILLDRGYSVSGSDLSEGKTVEKLKAKGARFFLGHQEEHVPEDAVVVYSSSISKD-NVEYLSAK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 95 RRRISLIPRAEMLGELIRMKFGVGVAGTHGKTTTTSMAGLVVAEGGFDPTVIVGGkVTAFGSNAITGEGDVLVIEADEYD 174
Cdd:PRK14573 85 SRGNRLVHRAELLAELMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIGG-LNQEGLNGYSGSSEYFVAEADESD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 175 RTFLRLTPSLAVITSIEEDHLDVYE-DLAAIQAAFTQYANSVpffgaailclDDPNVQAIVGDVER---RVV--TYGTTR 248
Cdd:PRK14573 164 GSLKHYTPEFSVITNIDNEHLSNFEgDRELLLASIQDFARKV----------QQINKCFYNGDCPRlkgCLQghSYGFSS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 249 QAEVRGENVRREGMTTRFDVVVRGERLGTIELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRFEKKGEV 328
Cdd:PRK14573 234 SCDLHILSYYQEGWRSYFSAKFLGVVYQDIELNLVGMHNVANAAAAMGIALTLGIDEGAIRNALKGFSGVQRRLERKNSS 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 329 GGITVLDDYAHHPTEIEATLDAAHQGFPDRRVVAVFQPHMYSRTQNFMDEFARSFFNADMLVLTDVYGAREAPIEGVTGG 408
Cdd:PRK14573 314 ETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFSRLRECLDSFPSAFQDADEVILTDVYSAGEEPEDSISYQ 393
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 2255965446 409 RLAERAEQFGHRAVHYVPEkTDLPGRLQELVGPGDVVLMLGAGDIWRASEA 459
Cdd:PRK14573 394 KLAEAISQSSIVKCTYVPF-HEIQRYLEQSIRVHDVCVSLGAGNIYTLGEA 443
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
19-361 |
5.75e-45 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 162.94 E-value: 5.75e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 19 VGIGGIGMS--SIAEVLLNRGYTVTGSDL--ERSDVTERLEAQGATIHEG-HAAEQVGTADVVVYSSAVDPDeNPETREA 93
Cdd:COG0771 7 VLVLGLGKSglAAARLLAKLGAEVTVSDDrpAPELAAAELEAPGVEVVLGeHPEELLDGADLVVKSPGIPPD-HPLLKAA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 94 ERRRISLIPRAEMLGELIRMKFgVGVAGTHGKTTTTSMAGLVVAEGGFDptVIVGGKV-TAFgSNAI--TGEGDVLVIEA 170
Cdd:COG0771 86 RAAGIPVIGEIELAYRLSPAPI-IAITGTNGKTTTTTLIGHILKAAGLR--VAVGGNIgTPL-LDLLlePEPPDVYVLEL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 171 DEY--DRTFlRLTPSLAVITSIEEDHLDVYEDLAA-IQAAFTQYANSVPFfGAAILCLDDPNVQAIVGDVERRVVTYGTT 247
Cdd:COG0771 162 SSFqlETTP-SLRPDVAVILNITPDHLDRHGSMEAyAAAKARIFANQTPD-DYAVLNADDPLTRALAEEAKARVVPFSLK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 248 RQAE----VRGENVRregmttrfdVVVRGERLGTI-ELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRF 322
Cdd:COG0771 240 EPLEggagLEDGKLV---------DRASGEELLPVdDLRLPGRHNLENALAALAAARALGVPPEAIREALRSFKGLPHRL 310
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 2255965446 323 EKKGEVGGITVLDD-YAhhpTEIEATLdAAHQGFpDRRVV 361
Cdd:COG0771 311 EFVAEINGVRFINDsKA---TNPDATL-AALESF-DGPVV 345
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
117-364 |
4.05e-37 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 141.75 E-value: 4.05e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 117 VGVAGTHGKTTTTSM-------AGLVVA-----EGGFDPTVIVGGKVTafgSNAIT---------GEG-DVLVIEAD--- 171
Cdd:COG0769 83 IGVTGTNGKTTTTYLlaqilraLGKKTGligtvGNGIGGELIPSSLTT---PEALDlqrllaemvDAGvTHVVMEVSsha 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 172 -EYDRTF-LRLtpSLAVITSIEEDHLDVYEDLAAIQAA----FTQYANSvpffGAAILCLDDPNVQAIVGDVERRVVTYG 245
Cdd:COG0769 160 lDQGRVDgVRF--DVAVFTNLTRDHLDYHGTMEAYFAAkarlFDQLGPG----GAAVINADDPYGRRLAAAAPARVITYG 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 246 TTRQAEVRGENVRREGMTTRFDVVVRGERlGTIELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRFEKK 325
Cdd:COG0769 234 LKADADLRATDIELSADGTRFTLVTPGGE-VEVRLPLIGRFNVYNALAAIAAALALGIDLEEILAALEKLKGVPGRMERV 312
|
250 260 270
....*....|....*....|....*....|....*....
gi 2255965446 326 GEVGGITVLDDYAHHPTEIEATLDAAHQgFPDRRVVAVF 364
Cdd:COG0769 313 DGGQGPTVIVDYAHTPDALENVLEALRP-HTKGRLIVVF 350
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
19-350 |
6.20e-36 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 137.86 E-value: 6.20e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 19 VGIGGIGMS--SIAEVLLNRGYTVTGSDL----ERSDVTERLEA-QGATIHEGHAAEQVGTADVVVYSSAVDPDeNPETR 91
Cdd:TIGR01087 2 ILILGLGKTgrAVARFLHKKGAEVTVTDLkpneELEPSMGQLRLnEGSVLHTGLHLEDLNNADLVVKSPGIPPD-HPLVQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 92 EAERRRISLIPRAEMLGELIRMKFgVGVAGTHGKTTTTSMAGLVVAEGGFDptVIVGGKVTAFGSNAITGEG-DVLVIEA 170
Cdd:TIGR01087 81 AAAKRGIPVVGDIELFLRLVPLPV-VAITGTNGKTTTTSLLYHLLKAAGLK--AFLGGNIGTPALEVLDQEGaELYVLEL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 171 D----EYDRTFlrlTPSLAVITSIEEDHLDVYEDLAA-IQAAFTQYANSvPFFGAAILCLDDPNVQAIVGDVERRVVTYG 245
Cdd:TIGR01087 158 SsfqlETTESL---RPEIALILNISEDHLDWHGSFEDyVAAKLKIFARQ-TEGDVAVLNADDPRFARLAQKSKAQVIWFS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 246 TTRQAEvRGENVRREGMTTRFDVVvrgerlgtiELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRFEKK 325
Cdd:TIGR01087 234 VEKDAE-RGLCIRDGGLYLKPNDL---------EGSLLGLHNAENILAAIALAKSLGLNLEAILEALRSFKGLPHRLEYV 303
|
330 340
....*....|....*....|....*
gi 2255965446 326 GEVGGITVLDDYAhhPTEIEATLDA 350
Cdd:TIGR01087 304 GQKNGVHFYNDSK--ATNVHATLAA 326
|
|
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
107-446 |
4.15e-35 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 136.00 E-value: 4.15e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 107 LGELIRMKFG---VGVAGTHGKTTTTSMAGLVVAEGGfdptvivggKVTA-FGS--NAI---------TGEGDVLVIE-- 169
Cdd:COG0770 90 LAAAHRARFNipvIAITGSNGKTTTKEMLAAVLSTKG---------KVLAtPGNfnNEIgvpltllrlPEDHEFAVLEmg 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 170 ---ADEYDRtflrLT----PSLAVITSIEEDHLDVYEDLAAIQAAFTQYANSVPFFGAAILCLDDPNVQAIVGDVERRVV 242
Cdd:COG0770 161 mnhPGEIAY----LAriarPDIAVITNIGPAHLEGFGSLEGIARAKGEIFEGLPPGGVAVLNADDPLLAALAERAKARVL 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 243 TYGTTRQAEVRGENVRREGMTTRFDVVVRGERLgTIELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRF 322
Cdd:COG0770 237 TFGLSEDADVRAEDIELDEDGTRFTLHTPGGEL-EVTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKGRL 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 323 EKKGEVGGITVLDD-YAHHPTEIEATLDAAHQGFPDRRVVAVFqphmysrtqnfmdefarsffnADMLVLtdvyG----- 396
Cdd:COG0770 316 EVIEGAGGVTLIDDsYNANPDSMKAALDVLAQLPGGGRRIAVL---------------------GDMLEL----Geesee 370
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 397 --------AREAPIEGV-TGGRLAER-AEQFGHRAVHYVPEKTDLPGRLQELVGPGDVVL 446
Cdd:COG0770 371 lhrevgelAAELGIDRLfTVGELARAiAEAAGGERAEHFEDKEELLAALKALLRPGDVVL 430
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
14-336 |
2.14e-30 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 122.77 E-value: 2.14e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 14 RQVHMVGIGGIGMSSiAEVLLNRGYTVTGSDL-ERSDVTERLEAQGATIHE----GHAAEQVGTADVVVYSSAVDPDENP 88
Cdd:PRK14106 6 KKVLVVGAGVSGLAL-AKFLKKLGAKVILTDEkEEDQLKEALEELGELGIElvlgEYPEEFLEGVDLVVVSPGVPLDSPP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 89 eTREAERRRISLIPRAEMLGELIRmKFGVGVAGTHGKTTTTSMAGLVVAEGGFDpTVIVGGKVTAFGSNAI-TGEGDVLV 167
Cdd:PRK14106 85 -VVQAHKKGIEVIGEVELAYRFSK-APIVAITGTNGKTTTTTLLGEIFKNAGRK-TLVAGNIGYPLIDAVEeYGEDDIIV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 168 IEADEYD-RTFLRLTPSLAVITSIEEDHLDVYEDLAA-IQAAFTQYANSVPFfGAAILCLDDPNVQAIVGDVERRVVTYG 245
Cdd:PRK14106 162 AEVSSFQlETIKEFKPKVGCILNITPDHLDRHKTMENyIKAKARIFENQRPS-DYTVLNYDDPRTRSLAKKAKARVIFFS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 246 TTRQAEvRGENVRREGMTTRFDvvvrGERLGTI---ELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRF 322
Cdd:PRK14106 241 RKSLLE-EGVFVKNGKIVISLG----GKEEEVIdidEIFIPGEHNLENALAATAAAYLLGISPDVIANTLKTFKGVEHRI 315
|
330
....*....|....
gi 2255965446 323 EKKGEVGGITVLDD 336
Cdd:PRK14106 316 EFVAEINGVKFIND 329
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
119-298 |
7.53e-25 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 101.61 E-value: 7.53e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 119 VAGTHGKTTTTSMAGLVV-AEGGFDPTVIVGGKVTAFGSNAITG-----------EGDVLVIEADEYDRTFLRLT----P 182
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILsLAGGVIGTIGTYIGKSGNTTNNAIGlpltlaemveaGAEYAVLEVSSHGLGEGRLSgllkP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 183 SLAVITSIEEDHLDVYEDLAAIQAAFTQYANSVPFFGAAILCLDDPNVQAIVGDVER---RVVTYGTTRQAEVRGENVRR 259
Cdd:pfam08245 81 DIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIAKLKKagvRVITYGIEGEADLRAANIEL 160
|
170 180 190
....*....|....*....|....*....|....*....
gi 2255965446 260 EGMTTRFDVVVRGERLGTIELHVPGMHNVRNALAAVAVG 298
Cdd:pfam08245 161 SSDGTSFDLFTVPGGELEIEIPLLGRHNVYNALAAIAAA 199
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
117-364 |
1.82e-19 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 90.58 E-value: 1.82e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 117 VGVAGTHGKTTTTSM-------AGLVVA-----EGGFDPTVIVGGKVTAFgsnAIT---------GEG-DVLVIEA---- 170
Cdd:PRK00139 98 IGVTGTNGKTTTAYLlaqilrlLGEKTAligtlGNGIGGELIPSGLTTPD---ALDlqrllaelvDAGvTYAAMEVssha 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 171 -DEyDRTF-LRLtpSLAVITSIEEDHLDVYEDLAAIQAA----FTQYAnsvpffGAAILCLDDPNVQAIVgdveRRVVTY 244
Cdd:PRK00139 175 lDQ-GRVDgLKF--DVAVFTNLSRDHLDYHGTMEDYLAAkarlFSELG------LAAVINADDEVGRRLL----ALPDAY 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 245 GTTRQ-AEVRGENVRREGMTTRFDVVvrgerlGTIELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRFE 323
Cdd:PRK00139 242 AVSMAgADLRATDVEYTDSGQTFTLV------TEVESPLIGRFNVSNLLAALAALLALGVPLEDALAALAKLQGVPGRME 315
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2255965446 324 KKGEVGGITVLDDYAHHPTEIEATLDAAHQgFPDRRVVAVF 364
Cdd:PRK00139 316 RVDAGQGPLVIVDYAHTPDALEKVLEALRP-HAKGRLICVF 355
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
16-114 |
6.56e-19 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 81.13 E-value: 6.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 16 VHMVGIGGIGMSSIAEVLLNRGYTVTGSDLERSdvterLEAQGATIHEGHAAEQVGTADvvvyssavdpdeNPETREAER 95
Cdd:pfam01225 2 IHFVGIDGRGMSPGALFLALKGYRVDGSDFIES-----LIALGAAAVVGHDAANNISPD------------NPELEAAKV 64
|
90
....*....|....*....
gi 2255965446 96 RRISLIPRAEMLGELIRMK 114
Cdd:pfam01225 65 PGIPVIDRREALAELAAAF 83
|
|
| murF |
TIGR01143 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the ... |
117-450 |
6.85e-19 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273468 [Multi-domain] Cd Length: 417 Bit Score: 88.48 E-value: 6.85e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 117 VGVAGTHGKTTTTSMAGLVVAEGGfdptvivggKVTAFGSN------------AITGEGDVLVIE--AD---EYDRTFLR 179
Cdd:TIGR01143 77 IGITGSSGKTTTKEMLAAILSHKY---------KVFATPGNfnneiglpltllRAPGDHDYAVLEmgAShpgEIAYLAEI 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 180 LTPSLAVITSIEEDHLDVYEDLAAIQAAFTQYANSVPFFGAAILCLDDPNVQAIVGDV-ERRVVTYGTTRqAEVRGENVR 258
Cdd:TIGR01143 148 AKPDIAVITNIGPAHLEGFGSLEGIAEAKGEILQGLKENGIAVINADDPAFADLAKRLpNRNILSFGFEG-GDFVAKDIS 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 259 R--EGMTtRFDVVVRGERLgTIELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRFEKKgEVGGITVLDD 336
Cdd:TIGR01143 227 YsaLGST-SFTLVAPGGEF-EVSLPLLGRHNVMNALAAAALALELGIPLEEIAEGLAELKLVKGRFEVQ-TKNGLTLIDD 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 337 -YAHHPTEIEATLDAAHQgFPDRRVVAVfqPHM-----YSRTqnFMDEFARSffnadmlvltdvygAREAPIEGV-TGGR 409
Cdd:TIGR01143 304 tYNANPDSMRAALDALAR-FPGKKILVL--GDMaelgeYSEE--LHAEVGRY--------------ANSLGIDLVfLVGE 364
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 2255965446 410 LAERAEQFGHRAVHYVPEKTDLPGRLQELVGPGDVVLMLGA 450
Cdd:TIGR01143 365 EAAVIYDSFGKQGKHFADKDELLAFLKTLVRKGDVVLVKGS 405
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
318-405 |
2.11e-17 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 77.00 E-value: 2.11e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 318 VRRRFEKKGEVGGITVLDDYAHHPTEIEATLDAAhQGFPDRRVVAVFQPhMYSRTQNFMDEFARSF-FNADMLVLTDVYG 396
Cdd:pfam02875 1 VPGRLEVVGENNGVLVIDDYAHNPDAMEAALRAL-RNLFPGRLILVFGG-MGDRDAEFHALLGRLAaALADVVILTGDYP 78
|
....*....
gi 2255965446 397 AREAPIEGV 405
Cdd:pfam02875 79 RAEDPGAII 87
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
104-364 |
8.57e-17 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 83.60 E-value: 8.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 104 AEMLGELIRMKFG--------VGVAGTHGKTTTTSM-----------AGLVVAEGGFDPTVIVGGKVT---AFGSNAITG 161
Cdd:PRK11929 94 RKALGELAARWYGrpseqlslVAVTGTNGKTSCAQLlaqlltrlgkpCGSIGTLGARLDGRLIPGSLTtpdAIILHRILA 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 162 E-----GDVLVIEADEYDRTFLRL---TPSLAVITSIEEDHLDVYEDLAAIQAAFTQYANSVPFFGAAILCLDDPNVQAi 233
Cdd:PRK11929 174 RmraagADAVAMEASSHGLEQGRLdglRIAVAGFTNLTRDHLDYHGTMQDYEEAKAALFSKLPGLGAAVINADDPAAAR- 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 234 VGDVERRVVTYGTTRQ---AEVRGENVRREGMTTRFDVVVRGERLgTIELHVPGMHNVRNALAAVAVGQELEISFERVRD 310
Cdd:PRK11929 253 LLAALPRGLKVGYSPQnagADVQARDLRATAHGQVFTLATPDGSY-QLVTRLLGRFNVSNLLLVAAALKKLGLPLAQIAR 331
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2255965446 311 GLGTFTGVRRRFEKKGEVGGIT---VLDDYAHHPTEIEATLDAAH--QGFPDRRVVAVF 364
Cdd:PRK11929 332 ALAAVSPVPGRMERVGPTAGAQgplVVVDYAHTPDALAKALTALRpvAQARNGRLVCVF 390
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
62-350 |
1.71e-16 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 82.44 E-value: 1.71e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 62 HEGHA----AEQVGTADVVVYSSAVDPD----ENPETREAerrrislipraemLGELIRM---KFG---VGVAGTHGKTT 127
Cdd:PRK11929 550 FDGHDylpqAFAAGACAAVVERQVADVDlpqiVVDDTRAA-------------LGRLATAwraRFSlpvVAITGSNGKTT 616
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 128 TTSMAGLVVAEGGFDPTVI---------VGGKVTAFgsnAITGEGDVLVIE-----ADEYDRTFLRLTPSLAVITSIEED 193
Cdd:PRK11929 617 TKEMIAAILAAWQGEDRVLategnfnneIGVPLTLL---RLRAQHRAAVFElgmnhPGEIAYLAAIAAPTVALVTNAQRE 693
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 194 HLDVYEDLAAIQAAFTQYANSVPFFGAAILCLDDPNVQAIV-GDVERRVVTYGTTRQAEVRGENVRREGMT-----TRFD 267
Cdd:PRK11929 694 HQEFMHSVEAVARAKGEIIAALPEDGVAVVNGDDPYTAIWAkLAGARRVLRFGLQPGADVYAEKIAKDISVgeaggTRCQ 773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 268 VVVRGErLGTIELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRFEKKGEVGGITVLDD-YAHHPTEIEA 346
Cdd:PRK11929 774 VVTPAG-SAEVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQPVAGRMQRRRLSCGTRIIDDtYNANPDSMRA 852
|
....
gi 2255965446 347 TLDA 350
Cdd:PRK11929 853 AIDV 856
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
117-364 |
1.22e-15 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 78.90 E-value: 1.22e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 117 VGVAGTHGKTTTTSM-------AGLVVAEGGFDPTVIVGGKVTAFGSNAITGE---------------GDVLVIEADEYD 174
Cdd:TIGR01085 88 IGVTGTNGKTTTTSLiaqllrlLGKKTGLIGTIGYRLGGNDLIKNPAALTTPEaltlqstlaemveagAQYAVMEVSSHA 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 175 RTFLRLTP---SLAVITSIEEDHLDVYEDLAAIQAAFTQYANSVPFFGAAILCLDDPNVQAIVGDVERRVVTYGTTRQAE 251
Cdd:TIGR01085 168 LAQGRVRGvrfDAAVFTNLSRDHLDFHGTMENYFAAKASLFTELGLKRFAVINLDDEYGAQFVKRLPKDITVSAITQPAD 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 252 VRGENVRREGMTTR-----FDVVVRGerlGTIELHVP--GMHNVRNALAAVAVG-QELEISFERVRDGLGTFTGVRRRFE 323
Cdd:TIGR01085 248 GRAQDIKITDSGYSfegqqFTFETPA---GEGHLHTPliGRFNVYNLLAALATLlHLGGIDLEDIVAALEKFRGVPGRME 324
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2255965446 324 KKGEVGGITVLDDYAHHPTEIEATLDAAhQGFPDRRVVAVF 364
Cdd:TIGR01085 325 LVDGGQKFLVIVDYAHTPDALEKALRTL-RKHKDGRLIVVF 364
|
|
| PRK14016 |
PRK14016 |
cyanophycin synthetase; Provisional |
117-316 |
4.53e-13 |
|
cyanophycin synthetase; Provisional
Pssm-ID: 237586 [Multi-domain] Cd Length: 727 Bit Score: 71.34 E-value: 4.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 117 VGVAGTHGKTTTT-------SMAGLVVaegGFDPT--VIVGGKVTAFGSNaiTG-----------EGDVLVIEADE---- 172
Cdd:PRK14016 483 VAVTGTNGKTTTTrliahilKLSGKRV---GMTTTdgVYIDGRLIDKGDC--TGpksarrvlmnpDVEAAVLETARggil 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 173 -----YDRTflrltpSLAVITSIEEDHL---DVY--EDLAAIQAafTQYANSVPFfGAAILCLDDPNVQAIVGDVERRVV 242
Cdd:PRK14016 558 reglaYDRC------DVGVVTNIGEDHLglgGINtlEDLAKVKR--VVVEAVKPD-GYAVLNADDPMVAAMAERCKGKVI 628
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 243 TYGTTRQAEVRGENVRREGMTtrfdVVVRGERL----GTIELHVP----------GM--HNVRNALAAVAVGQELEISFE 306
Cdd:PRK14016 629 FFSMDPDNPVIAEHRAQGGRA----VYVEGDYIvlaeGGWEIRIIsladipltlgGKagFNIENALAAIAAAWALGIDIE 704
|
250
....*....|
gi 2255965446 307 RVRDGLGTFT 316
Cdd:PRK14016 705 LIRAGLRTFV 714
|
|
| FolC |
COG0285 |
Folylpolyglutamate synthase/Dihydropteroate synthase [Coenzyme transport and metabolism]; ... |
180-446 |
9.33e-10 |
|
Folylpolyglutamate synthase/Dihydropteroate synthase [Coenzyme transport and metabolism]; Folylpolyglutamate synthase/Dihydropteroate synthase is part of the Pathway/BioSystem: Folate biosynthesis
Pssm-ID: 440054 [Multi-domain] Cd Length: 423 Bit Score: 60.50 E-value: 9.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 180 LTPSLAVITSIEEDHLDVY-EDLAAIqaAFTQyansvpffgAAILcldDPNVQAIVGDVE---RRVVtygtTRQAEVRGE 255
Cdd:COG0285 153 IDPLVSVITSIGLDHTDFLgDTLEEI--AREK---------AGII---KPGVPVVTGDQQpeaLEVI----EERAAELGA 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 256 NVRREGM--------TTRFDVVVRGERLGTIELHVPGMHNVRNALAAVAV-----GQELEISFERVRDGLGTfTGVRRRF 322
Cdd:COG0285 215 PLYRAGRdfsveereGAVFSYQGPGGEYEDLPLPLLGAHQAENAALALAAlealrELGLPISEEAIREGLAN-ARWPGRL 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 323 EKKGEvgGITVLDDYAHHPTEIEATLDAAHQGFPDRRVVAVF-----QPHmysrtQNFMDEFARsffNADMLVLTDVYGA 397
Cdd:COG0285 294 EVLSR--GPLVILDGAHNPAGARALAETLKELFPFRKLHLVFgmladKDI-----EGMLAALAP---LADEVIVTTPPSP 363
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 2255965446 398 REAPIEgvtggRLAERAEQFGHRaVHYVPEKTDLPGRLQELVGPGDVVL 446
Cdd:COG0285 364 RALDAE-----ELAEAARELGLR-VEVAPDVEEALEAALELADPDDLIL 406
|
|
| PRK14093 |
PRK14093 |
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; ... |
182-349 |
4.65e-07 |
|
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional
Pssm-ID: 184501 [Multi-domain] Cd Length: 479 Bit Score: 52.08 E-value: 4.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 182 PSLAVITSIEEDHLDVYEDLAAIQAAFTQYANSVPFFGAAILCLDDPNVQAIVGDVER----RVVTYGTTRQAEVRGENV 257
Cdd:PRK14093 184 PHVAIITTVEPVHLEFFSGIEAIADAKAEIFTGLEPGGAAVLNRDNPQFDRLAASARAagiaRIVSFGADEKADARLLDV 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 258 RREGMTTRFDVVVRGERLgTIELHVPGMHNVRNALAAVA----VGQELEIS---FERVRDGLGtfTGVRRRFEKKGevGG 330
Cdd:PRK14093 264 ALHADCSAVHADILGHDV-TYKLGMPGRHIAMNSLAVLAaaelAGADLALAalaLSQVQPAAG--RGVRHTLEVGG--GE 338
|
170 180
....*....|....*....|
gi 2255965446 331 ITVLDD-YAHHPTEIEATLD 349
Cdd:PRK14093 339 ATLIDEsYNANPASMAAALG 358
|
|
| PLN02913 |
PLN02913 |
dihydrofolate synthetase |
164-363 |
1.24e-03 |
|
dihydrofolate synthetase
Pssm-ID: 178501 [Multi-domain] Cd Length: 510 Bit Score: 41.34 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 164 DVLVIEAD---EYDRTFLRLTPSLA--VITSIEEDHLDVY----EDLAAIQAAFTQYANSV----PFFgaailclddPNV 230
Cdd:PLN02913 175 DIAVIEAGlggARDATNVIDSSGLAasVITTIGEEHLAALggslESIALAKSGIIKQGRPVvlggPFL---------PHI 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 231 QAIVGD----VERRVVT-YGTTRQAEVRGENVRREGMTTRFDVVVRGER-------LGTIELHVPGMHNVRNALAAVAVG 298
Cdd:PLN02913 246 ESILRDkassMNSPVVSaSDPGVRSSIKGIITDNGKPCQSCDIVIRVEKddplfieLSDVNLRMLGSHQLQNAVTAACAA 325
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2255965446 299 -----QELEISFERVRDGL-GTFTGVRRRF--EKKGEVGGI---TVLDDYAHHPTEIEATLDAAHQGFPDRRVVAV 363
Cdd:PLN02913 326 lclrdQGWRISDASIRAGLeNTNLLGRSQFltSKEAEVLGLpgaTVLLDGAHTKESAKALVDTIKTAFPEARLALV 401
|
|
| murF |
PRK10773 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed |
182-321 |
1.60e-03 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed
Pssm-ID: 182718 [Multi-domain] Cd Length: 453 Bit Score: 40.79 E-value: 1.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2255965446 182 PSLAVITSIEEDHLDVYEDLAAIQAAFTQYANSVPFFGAAILCLDD---PNVQAIVGDveRRVVTYGTTRQAEVR--GEN 256
Cdd:PRK10773 176 PEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADSndwLNWQSVIGS--KTVWRFSPNAANSVDftATN 253
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2255965446 257 VRREGMTTRFdvvVRGERLGTIE--LHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRR 321
Cdd:PRK10773 254 IHVTSHGTEF---TLHTPTGSVDvlLPLPGRHNIANALAAAALAMSVGATLDAVKAGLANLKAVPGR 317
|
|
| NAD_binding_2 |
pfam03446 |
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of ... |
21-83 |
5.72e-03 |
|
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold.
Pssm-ID: 427298 [Multi-domain] Cd Length: 159 Bit Score: 37.45 E-value: 5.72e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2255965446 21 IGGIGM----SSIAEVLLNRGYTVTGSDLERSdVTERLEAQGATIHEGhAAEQVGTADVVV----YSSAVD 83
Cdd:pfam03446 2 IGFIGLgvmgSPMALNLLKAGYTVTVYNRTPE-KVEELVAAGAIAAAS-PAEFVAGLDVVItmvpAGAAVD 70
|
|
| |
