NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2271089218|ref|WP_254398433|]
View 

MULTISPECIES: RNA polymerase sigma factor [unclassified Streptomyces]

Protein Classification

RNA polymerase sigma factor( domain architecture ID 11446377)

RNA polymerase sigma factor plays a role in bacterial signal transduction and is regulated by anti-sigma factors. May belong to the ECF-type subfamily. Generally, sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

CATH:  1.10.1740.10
Gene Ontology:  GO:0016987|GO:0006352|GO:0003677
PubMed:  28575802
SCOP:  4003741

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
 1-169 3.47e-26

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


:

Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 98.91  E-value: 3.47e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218   1 MAGNQDSWNRIVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLRDPEKLAQWIAVSARRESLKIIEKSGRSV 80
Cdd:COG1595    12 RAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  81 PVGDSPVFDRSEPSENhPEERALAKERDNEVLLAYCALSPKCQALLGLLVTDpPMSYDEISATLGMPRGSLGPIRARCLA 160
Cdd:COG1595    92 ELLDELAEELPDEAAD-PEEALEAEELLEALLAALERLPPRQREVLVLRYLE-GLSYAEIAEILGISEGTVKSRLSRARK 169


                  ....*....
gi 2271089218 161 HLGKLLQRE 169
Cdd:COG1595   170 KLREALEEE 178
 
Name Accession Description Interval E-value
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
 1-169 3.47e-26

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 98.91  E-value: 3.47e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218   1 MAGNQDSWNRIVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLRDPEKLAQWIAVSARRESLKIIEKSGRSV 80
Cdd:COG1595    12 RAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  81 PVGDSPVFDRSEPSENhPEERALAKERDNEVLLAYCALSPKCQALLGLLVTDpPMSYDEISATLGMPRGSLGPIRARCLA 160
Cdd:COG1595    92 ELLDELAEELPDEAAD-PEEALEAEELLEALLAALERLPPRQREVLVLRYLE-GLSYAEIAEILGISEGTVKSRLSRARK 169


                  ....*....
gi 2271089218 161 HLGKLLQRE 169
Cdd:COG1595   170 KLREALEEE 178
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
 6-166 8.90e-20

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 81.62  E-value: 8.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218   6 DSWNRIVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLRDPEKLAQWIAVSARRESLKIIEKSgRSVPVGDS 85
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEGSFKAWLFRIARNLILDYLRRK-RRLRRELD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  86 PVFDRSEPSENhPEERALAKERDNEVLLAYCALSPKCQALLGLLVTDpPMSYDEISATLGMPRGSLGPIRARCLAHLGKL 165
Cdd:TIGR02937  80 LLEELLDSDPS-PEEELEQEEEREALREALEKLPEREREVLVLRYLE-GLSYKEIAEILGISVGTVKRRLKRARKKLREL 157


                  .
gi 2271089218 166 L 166
Cdd:TIGR02937 158 L 158
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
 11-78 7.70e-07

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 44.89  E-value: 7.70e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  11 IVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLRD--PEKLAQWIAVSARRESLKIIEKSGR 78
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPerGVSFSTWLYTIIRNAIIDYLRKQRR 70
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
 10-172 1.78e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 46.12  E-value: 1.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  10 RIVERYTPliWAIARGHRL--SAADSEDVSQTTWMRVIQHLGKLRDPEKLAQWIAVSARRESLKIIEKSGRSVPVGDS-- 85
Cdd:PRK11924   17 ELFRPHAP--DLLRYARRQlgDRALAEDAVQEAFLRAWRKADLFNGKGSARTWLLTIARNVCYDLLRRRRREKAVLSDda 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  86 --PVFDRSEPSenhPEERALAKeRDNEVLLAYCALSPKCQALLGLLVTDPPMSYDEISATLGMPRGSLGPIRARCLAHLG 163
Cdd:PRK11924   95 lePEFAETAET---PEAALLAK-DDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVKSRLRRARQLLR 170


                  ....*....
gi 2271089218 164 KLLQRETER 172
Cdd:PRK11924  171 ECLEAQWEA 179
 
Name Accession Description Interval E-value
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
 1-169 3.47e-26

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 98.91  E-value: 3.47e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218   1 MAGNQDSWNRIVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLRDPEKLAQWIAVSARRESLKIIEKSGRSV 80
Cdd:COG1595    12 RAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  81 PVGDSPVFDRSEPSENhPEERALAKERDNEVLLAYCALSPKCQALLGLLVTDpPMSYDEISATLGMPRGSLGPIRARCLA 160
Cdd:COG1595    92 ELLDELAEELPDEAAD-PEEALEAEELLEALLAALERLPPRQREVLVLRYLE-GLSYAEIAEILGISEGTVKSRLSRARK 169


                  ....*....
gi 2271089218 161 HLGKLLQRE 169
Cdd:COG1595   170 KLREALEEE 178
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
 6-166 8.90e-20

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 81.62  E-value: 8.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218   6 DSWNRIVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLRDPEKLAQWIAVSARRESLKIIEKSgRSVPVGDS 85
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEGSFKAWLFRIARNLILDYLRRK-RRLRRELD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  86 PVFDRSEPSENhPEERALAKERDNEVLLAYCALSPKCQALLGLLVTDpPMSYDEISATLGMPRGSLGPIRARCLAHLGKL 165
Cdd:TIGR02937  80 LLEELLDSDPS-PEEELEQEEEREALREALEKLPEREREVLVLRYLE-GLSYKEIAEILGISVGTVKRRLKRARKKLREL 157


                  .
gi 2271089218 166 L 166
Cdd:TIGR02937 158 L 158
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
 11-78 7.70e-07

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 44.89  E-value: 7.70e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  11 IVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLRD--PEKLAQWIAVSARRESLKIIEKSGR 78
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPerGVSFSTWLYTIIRNAIIDYLRKQRR 70
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
 10-172 1.78e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 46.12  E-value: 1.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  10 RIVERYTPliWAIARGHRL--SAADSEDVSQTTWMRVIQHLGKLRDPEKLAQWIAVSARRESLKIIEKSGRSVPVGDS-- 85
Cdd:PRK11924   17 ELFRPHAP--DLLRYARRQlgDRALAEDAVQEAFLRAWRKADLFNGKGSARTWLLTIARNVCYDLLRRRRREKAVLSDda 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  86 --PVFDRSEPSenhPEERALAKeRDNEVLLAYCALSPKCQALLGLLVTDPPMSYDEISATLGMPRGSLGPIRARCLAHLG 163
Cdd:PRK11924   95 lePEFAETAET---PEAALLAK-DDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVKSRLRRARQLLR 170


                  ....*....
gi 2271089218 164 KLLQRETER 172
Cdd:PRK11924  171 ECLEAQWEA 179
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
 2-157 1.85e-06

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 46.34  E-value: 1.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218   2 AGNQDSWNRIVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLRDPEKLAQW---IAVSARRESLKiieKSGR 78
Cdd:PRK09652    6 RGDRAAFALLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAYRALHSFRGGAAFYTWlyrIARNTAINYLR---KQGR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  79 SVPVGDSPVFD------RSEPSE-NHPEERALAKERDNEVLLAYCALSPKCQALL------GLlvtdppmSYDEISATLG 145
Cdd:PRK09652   83 RPPASDVDAEEaedfdlADALRDiSTPENELLSAELEQRVRAAIESLPEELRTAItlreieGL-------SYEEIAEIMG 155

                         170
                  ....*....|..
gi 2271089218 146 MPrgsLGPIRAR 157
Cdd:PRK09652  156 CP---IGTVRSR 164
PRK09647 PRK09647
RNA polymerase sigma factor SigE; Reviewed
 7-182 7.82e-06

RNA polymerase sigma factor SigE; Reviewed


Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 44.78  E-value: 7.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218   7 SWNRIVERYTPLIWAIArgHRLS--AADSEDVSQTTWMRVIQHLGKLRdPEKLAQWIAVSARRESLKIIEKSGRSVPVGD 84
Cdd:PRK09647   29 SWEELVRQHADRVYRLA--YRLSgnQHDAEDLTQETFIRVFRSLQNYQ-PGTFEGWLHRITTNLFLDMVRRRARIRMEAL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  85 SPVFDRSEPSENHPEERALAKERDNEVLLAYCALSPKCQALLgLLVTDPPMSYDEISATLGMprgSLGPIRARC---LAH 161
Cdd:PRK09647  106 PEDYDRVPGDEPNPEQIYHDARLDPDLQAALDSLPPEFRAAV-VLCDIEGLSYEEIAATLGV---KLGTVRSRIhrgRQQ 181

                         170       180
                  ....*....|....*....|.
gi 2271089218 162 LGKLLQRETERSERATELLDA 182
Cdd:PRK09647  182 LRAALAAHAPHAECAALLNPA 202
PRK11922 PRK11922
RNA polymerase sigma factor; Provisional
 2-88 1.46e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 237024 [Multi-domain]  Cd Length: 231  Bit Score: 44.18  E-value: 1.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218   2 AGNQDSWNRIVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLRDPEKLAQWIAVSARRESLKIIEKSGRSVP 81
Cdd:PRK11922   26 AGDEAAFEALMRRHNRRLYRTARAILRNDAEAEDVVQEAYLRAFRALGTFRGDASLSTWLSRIVLNEALGRLRRRRRLVN 105


                  ....*..
gi 2271089218  82 VGDSPVF 88
Cdd:PRK11922  106 LAEMVMA 112
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
 14-165 2.10e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 40.43  E-value: 2.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  14 RYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKlrDPEK--LAQWIAV----------SARRESLKIIEKSGRSVP 81
Cdd:PRK12519   37 RHAGLVYGLALKILGNSQEAEDLTQEIFLSLWRKSSY--DPKRgsLSSYLLTltrsraidrlRSRRSRQRLLERWQQELL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  82 VgdspvfdrsEPSENHPEERALAKERDNEVLLAYCALSPKCQALLGLLVTDpPMSYDEISATLGMPrgsLGPIRARCLAH 161
Cdd:PRK12519  115 G---------EASEDTPLEQASLAERSQRVQTALAQLPESQRQVLELAYYE-GLSQSEIAKRLGIP---LGTVKARARQG 181


                  ....
gi 2271089218 162 LGKL 165
Cdd:PRK12519  182 LLKL 185
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
 26-100 4.71e-03

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 36.50  E-value: 4.71e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2271089218  26 HRLS-AADSEDVSQTTWMRVIQHLGKLRDPEKLAQWIAVSARRESLKIIEKSGRSVPVGDSPVFDRSEPSENHPEE 100
Cdd:PRK09637   20 SRVSnEADVDDLLQEVLIKTHSNLHSLKDGSSIKSWLYQIANNTIIDFYRKKNRSEELPDDLLFEDEEREENAKKE 95
PRK09639 PRK09639
RNA polymerase sigma factor SigX; Provisional
 34-172 5.32e-03

RNA polymerase sigma factor SigX; Provisional


Pssm-ID: 236602 [Multi-domain]  Cd Length: 166  Bit Score: 36.08  E-value: 5.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  34 EDVSQTTWMRVIQHlgKLRDPEKLAQWIAVSARRESLKII--EKSGRSVPVGdspVFDRSEPS-ENHPEERALAKErdnE 110
Cdd:PRK09639   31 EDLAQEVFLRLYRS--DFKGIENEKGWLIKSARNVAYNYLrsEKRRRARILG---EFQWQEVDnEPSPEEIWIRKE---E 102

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2271089218 111 VLLAYCALSpKC----QALLGLLVTDppMSYDEISATLGMPRGSLGPIRARCLAHLGKLLQRETER 172
Cdd:PRK09639  103 ITKVQEVLA-KMterdRTVLLLRFSG--YSYKEIAEALGIKESSVGTTLARAKKKFRKIYEQMEEE 165
PRK13919 PRK13919
putative RNA polymerase sigma E protein; Provisional
 3-166 6.21e-03

putative RNA polymerase sigma E protein; Provisional


Pssm-ID: 184395 [Multi-domain]  Cd Length: 186  Bit Score: 36.05  E-value: 6.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218   3 GNQDSWNRIVERYTPLIWAIARGHRLSAADSEDVSQTTWMRVIQHLGKLrDPEKLA--QWIAVSARRESLKIIeksgRSV 80
Cdd:PRK13919   20 GEEEALRALFRRYAGAFLALARRMGLDGAAAEDVVQEVFIRVWKKAKEF-DPRRGSarAWLLALAHHAAVDHV----RRR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271089218  81 PVGDSPVfdrsEPSENHPEERALAKERDNE--------VLLAYCALSPKCQALLGLLVTDpPMSYDEISATLGMPRGSLG 152
Cdd:PRK13919   95 AARPQPL----EPDEREPEAFDLPGPGLDEeghldrtrLGRALKALSPEERRVIEVLYYQ-GYTHREAAQLLGLPLGTLK 169

                         170
                  ....*....|....
gi 2271089218 153 PIRARCLAHLGKLL 166
Cdd:PRK13919  170 TRARRALSRLKEVL 183
PRK08295 PRK08295
RNA polymerase sporulation sigma factor SigH;
2-38 9.73e-03

RNA polymerase sporulation sigma factor SigH;


Pssm-ID: 181361 [Multi-domain]  Cd Length: 208  Bit Score: 35.65  E-value: 9.73e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2271089218   2 AGNQDSWNRIVERYTPLIWAIARGHRLSAADSEDVSQ 38
Cdd:PRK08295   20 SGDKEALEYLIEKYKNFVRAKARSYFLIGADREDIVQ 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH