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Conserved domains on  [gi|2289722154|ref|WP_258401773|]
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LuxR C-terminal-related transcriptional regulator, partial [Burkholderia multivorans]

Protein Classification

helix-turn-helix transcriptional regulator( domain architecture ID 11457944)

helix-turn-helix (HTH) transcriptional regulator containing a LuxR family HTH DNA-binding domain; may act as a transcription activator/repressor, or have a dual role for different sites; similar to Klebsiella aerogenes monoamine regulon transcriptional regulator

Gene Ontology:  GO:0006355|GO:0003677|GO:0003700
PubMed:  19076237|15808743|10473770|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 79-130 4.62e-17

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


:

Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 71.85  E-value: 4.62e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:COG2197    70 LTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELV 121
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
3-130 6.17e-09

DNA-binding transcriptional regulator, CsgD family [Transcription];


:

Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 51.68  E-value: 6.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289722154   3 ADVVEIWLRDDGRTVGAFSLLRFDTRGAARGGDGASARFAPGEIDALARLQPLAEAALSPLLRARRGIHRIECEA-RLTY 81
Cdd:COG2771    51 AAALAAALAAALLLGLLLLLLIALLLLLLLLLALLLLLALLALLAALLARLAALLLALALAALLLAALARLLARApGLTP 130

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2289722154  82 REEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:COG2771   131 REREVLRLLAEGLTLKEIARILGISERTVRTHLKRIYRKLGVSSRAELV 179
 
Name Accession Description Interval E-value
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 79-130 4.62e-17

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 71.85  E-value: 4.62e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:COG2197    70 LTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELV 121
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 77-130 5.54e-17

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 69.48  E-value: 5.54e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2289722154   77 ARLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:smart00421   2 ASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAV 55
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 79-130 1.51e-14

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 63.32  E-value: 1.51e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLV 52
GerE pfam00196
Bacterial regulatory proteins, luxR family;
79-130 7.46e-14

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 61.45  E-value: 7.46e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:pfam00196   3 LSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELV 54
PRK15369 PRK15369
two component system response regulator;
78-130 5.76e-12

two component system response regulator;


Pssm-ID: 185267 [Multi-domain]  Cd Length: 211  Bit Score: 60.09  E-value: 5.76e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2289722154  78 RLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:PRK15369  149 LLTPRERQILKLITEGYTNRDIAEQLSISIKTVETHRLNMMRKLDVHKVAELL 201
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
3-130 6.17e-09

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 51.68  E-value: 6.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289722154   3 ADVVEIWLRDDGRTVGAFSLLRFDTRGAARGGDGASARFAPGEIDALARLQPLAEAALSPLLRARRGIHRIECEA-RLTY 81
Cdd:COG2771    51 AAALAAALAAALLLGLLLLLLIALLLLLLLLLALLLLLALLALLAALLARLAALLLALALAALLLAALARLLARApGLTP 130

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2289722154  82 REEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:COG2771   131 REREVLRLLAEGLTLKEIARILGISERTVRTHLKRIYRKLGVSSRAELV 179
 
Name Accession Description Interval E-value
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 79-130 4.62e-17

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 71.85  E-value: 4.62e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:COG2197    70 LTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELV 121
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 77-130 5.54e-17

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 69.48  E-value: 5.54e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2289722154   77 ARLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:smart00421   2 ASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAV 55
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 71-134 9.97e-16

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 66.91  E-value: 9.97e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2289722154  71 HRIECEARLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELVGALF 134
Cdd:COG5905     5 SSTSHPSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWAL 68
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 79-130 1.51e-14

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 63.32  E-value: 1.51e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLV 52
GerE pfam00196
Bacterial regulatory proteins, luxR family;
79-130 7.46e-14

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 61.45  E-value: 7.46e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:pfam00196   3 LSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELV 54
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 46-130 2.08e-12

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 60.88  E-value: 2.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289722154  46 IDALARLQPLAEAALSPLLRARRGIHRIeceARLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSN 125
Cdd:COG4566   108 LDAVRRALARDRARRAERARRAELRARL---ASLTPREREVLDLVVAGLSNKQIARELGISPRTVEVHRANVMEKLGARS 184


                  ....*
gi 2289722154 126 RTELV 130
Cdd:COG4566   185 LAELV 189
PRK15369 PRK15369
two component system response regulator;
78-130 5.76e-12

two component system response regulator;


Pssm-ID: 185267 [Multi-domain]  Cd Length: 211  Bit Score: 60.09  E-value: 5.76e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2289722154  78 RLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:PRK15369  149 LLTPRERQILKLITEGYTNRDIAEQLSISIKTVETHRLNMMRKLDVHKVAELL 201
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
47-130 8.65e-12

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 59.33  E-value: 8.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289722154  47 DALARLQPLAEAALSPLLRARRGIHRIECEARLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNR 126
Cdd:COG2909    91 EALALLERLLALAEAAGRLLLRALALRALGDREEALAALRRRLLAEGLSNKEIAERLFISVNTVKTHLRNIYRKLGVRSR 170


                  ....
gi 2289722154 127 TELV 130
Cdd:COG2909   171 TEAV 174
PRK10100 PRK10100
transcriptional regulator CsgD;
60-130 8.79e-12

transcriptional regulator CsgD;


Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 59.88  E-value: 8.79e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2289722154  60 LSPLLRARRGIHRIE-CE-ARLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:PRK10100  135 LASYLITHSGNYRYNsTEsALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAV 207
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
79-130 1.45e-09

HTH-type transcriptional regulator MalT;


Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 54.57  E-value: 1.45e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:PRK04841  839 LTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGIAHRQEAV 890
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
3-130 6.17e-09

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 51.68  E-value: 6.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289722154   3 ADVVEIWLRDDGRTVGAFSLLRFDTRGAARGGDGASARFAPGEIDALARLQPLAEAALSPLLRARRGIHRIECEA-RLTY 81
Cdd:COG2771    51 AAALAAALAAALLLGLLLLLLIALLLLLLLLLALLLLLALLALLAALLARLAALLLALALAALLLAALARLLARApGLTP 130

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2289722154  82 REEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:COG2771   131 REREVLRLLAEGLTLKEIARILGISERTVRTHLKRIYRKLGVSSRAELV 179
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 77-128 3.17e-08

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 50.03  E-value: 3.17e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  77 ARLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTE 128
Cdd:PRK10651  154 NQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVE 205
PRK10360 PRK10360
transcriptional regulator UhpA;
38-134 1.14e-07

transcriptional regulator UhpA;


Pssm-ID: 182408 [Multi-domain]  Cd Length: 196  Bit Score: 48.43  E-value: 1.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289722154  38 SARFAPGEIDALARLQPLAEAALSPLLrarrgIHRIECEAR--LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLM 115
Cdd:PRK10360  100 SKRCSPDELIAAVHTVATGGCYLTPDI-----AIKLASGRQdpLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRA 174

                          90
                  ....*....|....*....
gi 2289722154 116 RMYRKLGVSNRTELVGALF 134
Cdd:PRK10360  175 NLMEKLGVSNDVELARRMF 193
PRK09935 PRK09935
fimbriae biosynthesis transcriptional regulator FimZ;
79-130 1.92e-06

fimbriae biosynthesis transcriptional regulator FimZ;


Pssm-ID: 182154 [Multi-domain]  Cd Length: 210  Bit Score: 45.25  E-value: 1.92e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTELV 130
Cdd:PRK09935  150 LSNREVTILRYLVSGLSNKEIADQLLLSNKTVSAHKSNIYGKLGLHSIVELI 201
PRK10188 PRK10188
transcriptional regulator SdiA;
36-129 3.81e-06

transcriptional regulator SdiA;


Pssm-ID: 182292 [Multi-domain]  Cd Length: 240  Bit Score: 44.39  E-value: 3.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289722154  36 GASARFAPGEIDALA-RLQPLAEAALSPLLRARRGIhRIECEARLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHL 114
Cdd:PRK10188  137 RCSAREIPILSDELElRLQLLVRESLMALMRLEDEM-VMTPEMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQ 215

                          90
                  ....*....|....*
gi 2289722154 115 MRMYRKLGVSNRTEL 129
Cdd:PRK10188  216 KNMQKKFNAPNKTQI 230
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
79-126 9.71e-04

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 37.52  E-value: 9.71e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNR 126
Cdd:PRK10403  154 LTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSR 201
PRK09483 PRK09483
response regulator; Provisional
 79-129 2.01e-03

response regulator; Provisional


Pssm-ID: 236538 [Multi-domain]  Cd Length: 217  Bit Score: 36.62  E-value: 2.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2289722154  79 LTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNRTEL 129
Cdd:PRK09483  149 LSERELQIMLMITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNISGDVEL 199
fixJ PRK09390
response regulator FixJ; Provisional
 48-130 5.00e-03

response regulator FixJ; Provisional


Pssm-ID: 181815 [Multi-domain]  Cd Length: 202  Bit Score: 35.36  E-value: 5.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2289722154  48 ALARLQPLA-EAALSPLLRARRgihrieceARLTYREEQIARLVRDGRSNKEIARDLALGQPTIKTHLMRMYRKLGVSNR 126
Cdd:PRK09390  118 ALAQAPEAAkSEAVAADIRARI--------ASLSERERQVMDGLVAGLSNKVIARDLDISPRTVEVYRANVMTKMQAGSL 189


                  ....
gi 2289722154 127 TELV 130
Cdd:PRK09390  190 SELV 193
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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