|
Name |
Accession |
Description |
Interval |
E-value |
| PBP1_ABC_LIVBP-like |
cd06342 |
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ... |
10-343 |
4.39e-136 |
|
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.
Pssm-ID: 380565 [Multi-domain] Cd Length: 334 Bit Score: 390.35 E-value: 4.39e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDeSGVSAVVGHFCSSST 89
Cdd:cd06342 1 KIGVAGPLTGPNAALGQDIRNGAELAVDEINAKGGGLGFKIELVAQDDACDPAQAVAAAQKLVA-DGVVAVIGHYNSGAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd06342 80 IAAAPIYAEAGIPMISPSATNPKLTEQGYKNFFRVVGTDDQQGPAAADYAAKTLKAKRVAVIHDGTAYGKGLADAFKKAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGGpqF 249
Cdd:cd06342 160 KALGGTVVGREGITPGTTDFSALLTKIKAANPDAVYFGGYYPEAGLLLRQLREAGLKAPFMGGDGIVSPDFIKAAGD--A 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 250 TNGVLMTFGKDP-RTISEGKTVIEKFRASGF-EPEGYTLYAYASIQAIAAAYNAVGADNTKA-SEWLKSHSVDTVMGKKA 326
Cdd:cd06342 238 AEGVYATTPGAPpEKLPAAKAFLKAYKAKFGePPGAYAAYAYDAAQVLLAAIEKAGSTDRAAvAAALRATDFDGVTGTIS 317
|
330
....*....|....*..
gi 2294037010 327 WDGKGDLKVSDYVVYAW 343
Cdd:cd06342 318 FDAKGDLTGPAFTVYQV 334
|
|
| PRK15404 |
PRK15404 |
high-affinity branched-chain amino acid ABC transporter substrate-binding protein; |
1-348 |
3.09e-129 |
|
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
Pssm-ID: 237959 [Multi-domain] Cd Length: 369 Bit Score: 374.36 E-value: 3.09e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 1 MAFCAQAD-VKIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDEsGVSA 79
Cdd:PRK15404 17 LSHAALADdIKIAIVGPMSGPVAQYGDMEFTGARQAIEDINAKGGIKGDKLEGVEYDDACDPKQAVAVANKVVND-GIKY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 80 VVGHFCSSSTMPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQ 159
Cdd:PRK15404 96 VIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLIFRTIGLDSDQGPTAAKYILEKVKPKRIAVLHDKQQYGE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 160 GLADATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEE 239
Cdd:PRK15404 176 GLARSVKDGLKKAGANVVFFEGITAGDKDFSALIAKLKKENVDFVYYGGYHPEMGQILRQAREAGLKTQFMGPEGVGNKS 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 240 LVTTAGGPqfTNGVLMTFGKDPRTISEGKTVIEKFRASGFEPEG-YTLYAYASIQAIAAAYNAVGADN-TKASEWLKSHS 317
Cdd:PRK15404 256 LSNIAGPA--SEGMLVTLPKRYDQDPANKAIVDAFKAKKQDPSGpFVWTTYAAVQSLAAGINRAGSDDpAKVAKYLKANT 333
|
330 340 350
....*....|....*....|....*....|.
gi 2294037010 318 VDTVMGKKAWDGKGDLKVSDYVVYAWDDKGK 348
Cdd:PRK15404 334 FDTVIGPLSWDEKGDLKGFEFGVFEWHADGT 364
|
|
| LivK |
COG0683 |
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ... |
6-349 |
6.52e-89 |
|
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];
Pssm-ID: 440447 [Multi-domain] Cd Length: 314 Bit Score: 269.49 E-value: 6.52e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 6 QADVKIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFC 85
Cdd:COG0683 1 ADPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAAGGVLGRKIELVVEDDASDPDTAVAAARKLIDQDKVDAIVGPLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 86 SSSTMPASEVYDEAGILTITPGSTNPLITERGMKD-MFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADA 164
Cdd:COG0683 81 SGVALAVAPVAEEAGVPLISPSATAPALTGPECSPyVFRTAPSDAQQAEALADYLAKKLGAKKVALLYDDYAYGQGLAAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 165 TRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFfsgdcvvteelvtta 244
Cdd:COG0683 161 FKAALKAAGGEVVGEEYYPPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKGPL--------------- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 245 ggpqftngvlmtfgkdprtiseGKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVGADNTKA-SEWLKSHSVDTVM 322
Cdd:COG0683 226 ----------------------NKAFVKAYKAKyGREPSSYAAAGYDAALLLAEAIEKAGSTDREAvRDALEGLKFDGVT 283
|
330 340
....*....|....*....|....*..
gi 2294037010 323 GKKAWDGKGDLkVSDYVVYAWDDKGKY 349
Cdd:COG0683 284 GPITFDPDGQG-VQPVYIVQVKADGKF 309
|
|
| PBP1_ABC_HAAT-like |
cd06349 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-332 |
2.11e-84 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380572 [Multi-domain] Cd Length: 338 Bit Score: 259.04 E-value: 2.11e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06349 1 KIGVSGPLTGDNAEYGQQFKNGVELAVDEINAAGGVNGRKLELVVYDDQGDPKEAVNIAQKFVSDDKVVAVIGDFSSSCS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGmKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd06349 81 MAAAPIYEEAGLVQISPTASHPDFTKGG-DYVFRNSPTQAVEAPFLADYAVKKLGAKKIAIIYLNTDWGVSAADAFKKAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGGPqf 249
Cdd:cd06349 160 KALGGEIVATEAYLPGTKDFSAQITKIKNANPDAIYLAAYYNDAALIAKQARQLGWDVQIFGSSSLYSPEFIELAGDA-- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 250 TNGVLMTFG-----KDPRTisegKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVGADNTKASEWLKSHSVDTVM- 322
Cdd:cd06349 238 AEGVYLSSPffpesPDPEV----KEFVKAYKAKyGEDPDDFAARAYDAVNILAEAIEKAGTDREAIRDALANIKDFSGLt 313
|
330
....*....|
gi 2294037010 323 GKKAWDGKGD 332
Cdd:cd06349 314 GTITFDENGD 323
|
|
| PBP1_ABC_LivK_ligand_binding-like |
cd06347 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-332 |
5.13e-82 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380570 [Multi-domain] Cd Length: 334 Bit Score: 252.85 E-value: 5.13e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06347 1 KIGVIGPLTGEAAAYGQPALNGAELAVDEINAAGGILGKKIELIVYDNKSDPTEAANAAQKLIDEDKVVAIIGPVTSSIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITErGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDK-DTYGQGLADATRAA 168
Cdd:cd06347 81 LAAAPIAQKAKIPMITPSATNPLVTK-GGDYIFRACFTDPFQGAALAKFAYEELGAKKAAVLYDVsSDYSKGLAKAFKEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVtTAGGPQ 248
Cdd:cd06347 160 FEKLGGEIVAEETYTSGDTDFSAQLTKIKAANPDVIFLPGYYEEAALIIKQARELGITAPILGGDGWDSPELL-ELGGDA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 249 FTNGVLMTFGKDPRTISEGKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAY-NAVGADNTKASEWLKSH-SVDTVMGKK 325
Cdd:cd06347 239 VEGVYFTTHFSPDDPSPEVQEFVKAYKAKyGEPPNAFAALGYDAVMLLADAIkRAGSTDPEAIRDALAKTkDFEGVTGTI 318
|
....*..
gi 2294037010 326 AWDGKGD 332
Cdd:cd06347 319 TFDPNGN 325
|
|
| PBP1_ABC_transporter_LIVBP-like |
cd06268 |
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ... |
10-296 |
7.72e-77 |
|
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.
Pssm-ID: 380492 [Multi-domain] Cd Length: 298 Bit Score: 238.38 E-value: 7.72e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06268 1 KIGVVVPLTGPYADYGEEILRGVALAVEEINAAGGINGRKLELVIADDQGDPETAVAVARKLVDDDKVLAVVGHYSSSVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd06268 81 LAAAPIYQEAGIPLISPGSTAPELTEGGGPYVFRTVPSDAMQAAALADYLAKKLKGKKVAILYDDYDYGKSLADAFKKAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDcVVTEELVTTAGGPQF 249
Cdd:cd06268 161 KALGGEIVAEEDFPLGTTDFSAQLTKIKAAGPDVLFLAGYGADAANALKQARELGLKLPILGGD-GLYSPELLKLGGEAA 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2294037010 250 TNGVLMTFGKDPRTISEGKTVIEKFRA-SGFEPEGYTLYAYASIQAIA 296
Cdd:cd06268 240 EGVVVAVPWHPDSPDPPKQAFVKAYKKkYGGPPSWRAATAYDATQALA 287
|
|
| PBP1_ABC_ligand_binding-like |
cd19980 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-340 |
5.24e-75 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380635 [Multi-domain] Cd Length: 334 Bit Score: 234.81 E-value: 5.24e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd19980 1 KIGVIAPLSGPVAALGQQVLNGAKLAVEEINAKGGVLGRKLELVVEDDKCPPAEGVAAAKKLITDDKVPAIIGAWCSSVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd19980 81 LAVMPVAERAKVPLVVEISSAPKITEGGNPYVFRLNPTNSMLAKAFAKYLADKGKPKKVAFLAENDDYGRGAAEAFKKAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGGPqf 249
Cdd:cd19980 161 KAKGVKVVATEYFDQGQTDFTTQLTKLKAANPDAIFVVAETEDGALILKQARELGLKQQLVGTGGTTSPDLIKLAGDA-- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 250 TNGVLMTFGKDPrTISEG--KTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVGADNTKA--SEWLKSHSVDTVMGK 324
Cdd:cd19980 239 AEGVYGASIYAP-TADNPanKAFVAAYKKKyGEPPDKFAALGYDAVMVIAEAIKKAGSTDPEKirAAALKKVDYKGPGGT 317
|
330
....*....|....*.
gi 2294037010 325 KAWDGKGDLKVSDYVV 340
Cdd:cd19980 318 IKFDEKGQAHKNVVLV 333
|
|
| PBP1_ABC_HAAT-like |
cd19988 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-296 |
4.33e-71 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380643 [Multi-domain] Cd Length: 302 Bit Score: 223.69 E-value: 4.33e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd19988 1 KIGVFGPLSGDAAPYGQAMLQGAELAVEEINAAGGILGIPIELVVEDDEGLPAASVSAAKKLIYQDKVWAIIGSINSSCT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd19988 81 LAAIRVALKAGVPQINPGSSAPTITESGNPWVFRCTPDDRQQAYALVDYAFEKLKVTKIAVLYVNDDYGRGGIDAFKDAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGGpqF 249
Cdd:cd19988 161 KKYGIEVVVEESYNRGDKDFSPQLEKIKDSGAQAIVMWGQYTEGALIAKQARELGLKQPLFGSDGLVTPKFIELAGD--A 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 2294037010 250 TNGVLMTFGKDPRTISEG-KTVIEKFRAS-GFEPEGYTLYAYASIQAIA 296
Cdd:cd19988 239 AEGAIATTPFLPDSDDPKvSAFVEKYKKRyGEEPDVFAAQAYDAMNILA 287
|
|
| PBP1_ABC_ligand_binding-like |
cd19984 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-296 |
1.10e-69 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380639 [Multi-domain] Cd Length: 296 Bit Score: 219.78 E-value: 1.10e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd19984 1 KIGVILPLTGDAASYGEDMKNGIELAVEEINAAGGINGKKIELIYEDSKCDPKKAVSAANKLINVDKVKAIIGGVCSSET 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGmkD-MFRMCGRDDQQGAIAANYMLDVLKaKKIAVIHDKDTYGQGLADATRAA 168
Cdd:cd19984 81 LAIAPIAEQNKVVLISPGASSPEITKAG--DyIFRNYPSDAYQGKVLAEFAYNKLY-KKVAILYENNDYGVGLKDVFKKE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGgpQ 248
Cdd:cd19984 158 FEELGGKIVASESFEQGETDFRTQLTKIKAANPDAIFLPGYPKEGGLILKQAKELGIKAPILGSDGFEDPELLEIAG--E 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 2294037010 249 FTNGVLMTFGKDPRTISEGKTVIEKFRASGF--EPEGYTLYAYASIQAIA 296
Cdd:cd19984 236 AAEGVIFTYPAFDDSSEKKQKFFFYRYKEKYgkEPDIYAALAYDAVMILA 285
|
|
| PBP1_ABC_ligand_binding-like |
cd06340 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
10-309 |
1.41e-64 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380563 [Multi-domain] Cd Length: 352 Bit Score: 208.57 E-value: 1.41e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIK---GEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCS 86
Cdd:cd06340 1 KIGVLYPLSGPLALIGQEAKRGAELAVDEINAAGGIKslgGAKIELVVADTQSDPEVAASEAERLITQEGVVAIIGAYSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 87 SSTMPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKA-----KKIAVIHDKDTYGQGL 161
Cdd:cd06340 81 SVTLAASQVAERYGVPFVTASAVADEITERGFKYVFRTAPTASQFAEDAVDFLKELAKKkgkkiKKVAIIYEDSAFGTSV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 162 ADATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFF--SGDCVVTEE 239
Cdd:cd06340 161 AKGLKKAAKKAGLEVVLDEPYPAGATDLSSEVLKLKAAKPDVVFATSYTNDAILLLRTMKELGFKPKAIigVGGGYSDPE 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2294037010 240 LVTTAGGpqFTNGVL-------MTFGKDPRTisegKTVIEKFRA-SGFEPEGYTLYAYASIQAIAAAYNAVGADNTKA 309
Cdd:cd06340 241 FLKALGK--DAEGVFsvvpwspDLAKKKPGA----KEVNERYKKkYGEDMTGHAARAYTAAWVLADALERAGSTDPEA 312
|
|
| PBP1_ABC_HAAT-like |
cd06344 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
8-334 |
3.90e-64 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380567 [Multi-domain] Cd Length: 332 Bit Score: 206.69 E-value: 3.90e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 8 DVKIGVAGPFtgpnASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSS 87
Cdd:cd06344 1 DIVIGVAWPF----APDGDLFLEGVELAVEEINAAGGVLGRKIRLVEYDDEASVDKGLAIAQRFADNPDVVAVIGHRSSY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 88 STMPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDvLKAKKIAVIHDKDTYGQGLADATRA 167
Cdd:cd06344 77 VAIPASIIYERAGLLMLSPGATAPKLTQHGFKYIFRNIPSDEDIARQLARYAAR-QGYKRIVIYYDDDSYGKGLANAFEE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 168 ALAKRGTKEVLYEGLSRGEKDFNALVTKIGAL-KPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGg 246
Cdd:cd06344 156 EARELGITIVDRRSYSSDEEDFRRLLSKWKALdFFDAIFLAGSMPEGAEFIKQARELGIKVPIIGGDGLDSPELIEIAG- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 247 pQFTNGVLMTFGKDP-RTISEGKTVIEKFRA-SGFEPEGYTLYAYASIQAIAAAYNAVGADNTKA--------SEWlksh 316
Cdd:cd06344 235 -KAAEGVVVATVFDPdDPRPEVRAFVEAFRKkYGREPDVWAAQGYDAVKLLAEAIEKAGSTVPAKiasalrflENW---- 309
|
330
....*....|....*...
gi 2294037010 317 svDTVMGKKAWDGKGDLK 334
Cdd:cd06344 310 --EGVTGTYSFDANGDVV 325
|
|
| PBP1_ABC_ligand_binding-like |
cd06346 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-304 |
5.69e-64 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380569 [Multi-domain] Cd Length: 314 Bit Score: 205.88 E-value: 5.69e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06346 1 KIGALLPLTGPLASLGPPMLAAAELAVEEINAAGGVLGKKVELVVEDSQTDPTAAVDAARKLVDVEGVPAIVGAASSGVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMKDM-FRMCGRDDQQGAIAANYMLDvLKAKKIAVIHDKDTYGQGLADATRAA 168
Cdd:cd06346 81 LAVASVAVPNGVVQISPSSTSPALTTLEDKGYvFRTAPSDALQGVVLAQLAAE-RGFKKVAVIYVNNDYGQGLADAFKKA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRG---TKEVLYEglsRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQA-KFFSGDCVVTEELVTTA 244
Cdd:cd06346 160 FEALGgtvTASVPYE---PGQTSYRAELAQAAAGGPDALVLIGYPEDGATILREALELGLDFtPWIGTDGLKSDDLVEAA 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2294037010 245 gGPQFTNGVLMTFGKDPRTISeGKTVIEKFRA-SGFEPEGYTLYAYASIQAIAAAYnaVGA 304
Cdd:cd06346 237 -GAEALEGMLGTAPGSPGSPA-YEAFAAAYKAeYGDDPGPFAANAYDAVMLLALAY--EGA 293
|
|
| PBP1_ABC_HAAT-like |
cd19981 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-296 |
7.19e-58 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380636 [Multi-domain] Cd Length: 297 Bit Score: 189.42 E-value: 7.19e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd19981 1 KIGFFAPLTGPAAADGKSALHGAELAVEQINAAGGINGKKVELVVYDDQASPKQAVNIAQKLIEQDKVVAVVSGSYSGPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGmKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd19981 81 RAAAPIFQEAKVPMVSAYAVHPDITKAG-DYVFRVAFLGPVQGRAGAEYAVKDLGAKKVAILTIDNDFGKSLAAGFKEEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGgpQF 249
Cdd:cd19981 160 KKLGAEIVSEYAYALGDRDFRPILTKIKSANPDAIYASGYYAEAAPIVKQARELGIKVPIIGQEGYDSPKFIEIAG--SA 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 2294037010 250 TNGVLMT--FGKD-PRTISegKTVIEKFR-ASGFEPEGYTLYAYASIQAIA 296
Cdd:cd19981 238 AEGVIITtsLNRDsDRPIT--QKFIKEYRkRYGIDPDMVAASTYDAVMVLA 286
|
|
| PBP1_ABC_ligand_binding-like |
cd06338 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
10-343 |
2.19e-57 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380561 [Multi-domain] Cd Length: 347 Bit Score: 189.72 E-value: 2.19e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGE----KIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFC 85
Cdd:cd06338 1 KIGASLSLTGPFAGEGKAQKRGYELWVEDVNAAGGVKGGgkkrPVELVYYDDQSDPATAVRLYEKLITEDKVDLLLGPYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 86 SSSTMPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLD-VLKAKKIAVIHDKDTYGQGLADA 164
Cdd:cd06338 81 SGLTLAAAPVAEKYGIPMIAGGAASDSIFERGYKYVFGVLPPASDYAKGLLDLLAElGPKPKTVAIVYEDDPFGKEVAEG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 165 TRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTA 244
Cdd:cd06338 161 AREAAKKAGLEVVYDESYPPGTTDFSPLLTKVKAANPDILLVGGYPPDAITLVRQMKELGYNPKAFFLTVGPAFPAFREA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 245 GGPQfTNGVL--------MTFGKDPRTisegKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVGA-DNTKASEWLK 314
Cdd:cd06338 241 LGKD-AEGVLgpsqwepsLPYKVFPGA----KEFVKAYKEKfGEEPSYHAAAAYAAGQVLQQAIEKAGSlDPEKVRDALA 315
|
330 340
....*....|....*....|....*....
gi 2294037010 315 SHSVDTVMGKKAWDGKGDLKVSDYVVYAW 343
Cdd:cd06338 316 SLDFDTVYGPIKFDETGLQIGKPMVVVQW 344
|
|
| Peripla_BP_6 |
pfam13458 |
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ... |
9-348 |
2.50e-54 |
|
Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.
Pssm-ID: 433225 [Multi-domain] Cd Length: 342 Bit Score: 181.70 E-value: 2.50e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 9 VKIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSS 88
Cdd:pfam13458 2 IKIGVLTPLSGPYASSGKSSRAGARAAIEEINAAGGVNGRKIELVVADDQGDPDVAAAAARRLVDQDGVDAIVGGVSSAV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 89 TMPASEVYDEAGILTITPGSTNPlitERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAA 168
Cdd:pfam13458 82 ALAVAEVLAKKGVPVIGPAALTG---EKCSPYVFSLGPTYSAQATALGRYLAKELGGKKVALIGADYAFGRALAAAAKAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGGPQ 248
Cdd:pfam13458 159 AKAAGGEVVGEVRYPLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDAKGIKLVGLGGDEPDLKALGGD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 249 FTNGVLMT--FGKDPRTiSEGKTVIEKF--RASGFEPEGYTLYAYASIQAIAAAYNAVGADNTKA-SEWLKSHSVDTVMG 323
Cdd:pfam13458 239 AAEGVYATvpFFPDLDN-PATRAFVAAFaaKYGEAPPTQFAAGGYIAADLLLAALEAAGSPTREAvIAALRALPYDGPFG 317
|
330 340
....*....|....*....|....*
gi 2294037010 324 KKAWDGKGDLKVSDYVVYAWDDKGK 348
Cdd:pfam13458 318 PVGFRAEDHQAVHCMYLVQVKADGK 342
|
|
| PBP1_ABC_RPA1789-like |
cd06333 |
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ... |
10-308 |
1.38e-53 |
|
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380556 [Multi-domain] Cd Length: 342 Bit Score: 179.67 E-value: 1.38e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06333 1 KIGAILSLTGPAASLGIPERNAVELLVEQINAAGGINGRKLELIVYDDESDPTKAVTNARKLIEEDKVDAIIGPSTTGES 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPlITERGMKDMFRMCGRDDQQGAIAANYMLDVlKAKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd06333 81 LAVAPIAEEAKVPLISLAGAAA-IVEPVRKWVFKTPQSDSLVAEAILDYMKKK-GIKKVALLGDSDAYGQSGRAALKKLA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGGPqf 249
Cdd:cd06333 159 PEYGIEIVADERFARTDTDMTAQLTKIRAAKPDAVLVWASGPPAALVAKNLRQLGYKGPIYQSHGAANQDFIKLAGKA-- 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 250 TNGVLMTFGK--DPRTISEG---KTVIEKFRAS-----GFEPEGYTLYAYASIQAIAAAY-NAVGADNTK 308
Cdd:cd06333 237 AEGVILPAGKllVADQLPDSdpqKKVLLEFVKAyeakyGEGPSTFAGHAYDALLLLVEAIePAGGTDRAA 306
|
|
| PBP1_ABC_ligand_binding-like |
cd06336 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
10-330 |
5.59e-53 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380559 [Multi-domain] Cd Length: 345 Bit Score: 178.20 E-value: 5.59e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIK--GE--KIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFC 85
Cdd:cd06336 1 KIGFLGPLSGPAAAWGLPMLRGLELAADEINAAGGIKvgGKkyKVEVVSYDDKYTPAEAVAAARRLVSQDGVKFIFGPGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 86 SSSTMPASEVYDEAGILTITPGSTNPlITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADAT 165
Cdd:cd06336 81 SAIAAAVQPVTERNKVLLLTAAFSDP-ILGPDNPLLFRIPPTPYEYAPPFIKWLKKNGPIKTVALIAPNDATGKDWAAAF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 166 RAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHP-EAGPLVRQMREQGLQAKFFSGDCVVTEELVtTA 244
Cdd:cd06336 160 VAAWKAAGGEVVAEEFYDRGTTDFYPVLTKILALKPDALDLGGSSPgPAGLIIKQARELGFKGPFVSEGGAKADEIL-KE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 245 GGPQFTNGVLMTFGKDPRTISE--GKTVIEKFRA-SGFEPEGYTLYAYASIQAIAAAYNAVG-ADNTKASEWL--KSHSV 318
Cdd:cd06336 239 VGGEAAEGFIGVLPADDDPIASpgAKAFVERYKKkYGEPPNSESALFYDAAYILVKAMEKAGtVDDTKKIRAAlaMLSPD 318
|
330
....*....|..
gi 2294037010 319 DTVMGKKAWDGK 330
Cdd:cd06336 319 ETLFGKLKWGGK 330
|
|
| PBP1_ABC_HAAT-like |
cd19986 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-296 |
1.49e-52 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380641 [Multi-domain] Cd Length: 297 Bit Score: 175.51 E-value: 1.49e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd19986 1 KIGVVAPLTGPAALNGEYQKNGAQLALEEINAAGGVLGRPLELVVEDDQGTNTGAVNAVNKLISDDKVVAVIGPHYSTQV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITpGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd19986 81 LAVSPLVKEAKIPVIT-GGTSPKLTEQGNPYMFRIRPSDSVSAKALAKYAVEELGAKKIAILYDNDDFGTGGADVVTAAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVyFGGCHPEAGPL-VRQMREQGLQAKFFSGDCVVTEELVTTAGgpQ 248
Cdd:cd19986 160 KALGLEPVAVESYNTGDKDFTAQLLKLKNSGADVI-IAWGHDAEAALiARQIRQLGLDVPVIGSSSFATPTVLLLAG--E 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 2294037010 249 FTNGVLMTFGKDPRTISE-GKTVIEKFRAS-GFEPEGYTLYAYASIQAIA 296
Cdd:cd19986 237 ALEGIYSVTDFVPSDPDPkVQAFVKKYKAKyGEDPDLYSAWYYDAMYLLA 286
|
|
| PBP1_ABC_ligand_binding-like |
cd06343 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
9-305 |
8.77e-52 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.
Pssm-ID: 380566 [Multi-domain] Cd Length: 355 Bit Score: 175.45 E-value: 8.77e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 9 VKIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSS 88
Cdd:cd06343 7 IKIGTSLPLSGPAAAYGKPVRAGAAAYFDEVNAAGGINGRKIELIVEDDGYDPARAVAAVRKLVEQDKVFAIVGGLGTPT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 89 TMPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAA 168
Cdd:cd06343 87 NLAVRPYLNEAGVPQLFPATGASALSPPPKPYTFGVQPSYEDEGRILADYIVETLPAAKVAVLYQNDDFGKDGLEGLKEA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGGPQ 248
Cdd:cd06343 167 LKAYGLEVVAEETYEPGDTDFSSQVLKLKAAGADVVVLGTLPKEAAAALKEAAKLGWKPTFLGSSVSADPTTLAKAGGDA 246
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2294037010 249 FTNGVLMTFGKDPRTIS--EGKTVIEKFRA--SGFEPEGYTLYAYASIQAIAAAYNAVGAD 305
Cdd:cd06343 247 AEGVYSASYLKDPTDADdpAVKEFREAYKKyfPDDPPNAYALYGYAAAQVFVEALKRAGKD 307
|
|
| PBP1_ABC_ligand_binding-like |
cd06335 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
10-309 |
5.10e-50 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380558 [Multi-domain] Cd Length: 348 Bit Score: 170.48 E-value: 5.10e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06335 1 KIGVIGPLTGPSAELGESARRGVELAVEEINAAGGILGRKIELVERDDEANPTKAVQNAQELIDKEKVVAIIGPTNSGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMKD---MFRMCGRDDQQGAIAANYMLDVlKAKKIAVIHDKDTYGQGLADATR 166
Cdd:cd06335 81 LATIPILQEAKIPLIIPVATGTAITKPPAKPrnyIFRVAASDTLQADFLVDYAVKK-GFKKIAILHDTTGYGQGGLKDVE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 167 AALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGG 246
Cdd:cd06335 160 AALKKRGITPVATESFKIGDTDMTPQLLKAKDAGADVILVYGLGPDLAQILKAMEKLGWKVPLVGSWGLSMPNFIELAGP 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2294037010 247 pqFTNGVLM--TFGKDPRTiSEGKTVIEKFRASGFEPEGYTLY----AYASIQAIAAAYNAVGADNTKA 309
Cdd:cd06335 240 --LAEGTIMtqTFIEDYLT-PRAKKFIDAYKKKYGTDRIPSPVsaaqGYDAVYLLAAAIKQAGSTDGKK 305
|
|
| PBP1_As_SBP-like |
cd06330 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
10-324 |
6.87e-50 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.
Pssm-ID: 380553 [Multi-domain] Cd Length: 342 Bit Score: 170.05 E-value: 6.87e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06330 1 KIGVITPLSGAAAVYGEPARNGAELAVEEINAAGGILGRKIELVVRDDKGKPDEAVRAARELVLQEGVDFLIGTISSGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLIT-ERGMKDMFRMCGRDDQQGAIAANYMLDVLK-AKKIAVIHDKDTYGQGLADATRA 167
Cdd:cd06330 81 LAVAPVAEELKVLFIATDAATDRLTeENFNPYVFRTSPNTYMDAVAAALYAAKKPPdVKRWAGIGPDYEYGRDSWAAFKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 168 ALAKRGTK-EVLYEGLSR-GEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGL--QAKFFSGDcvVTEELVTT 243
Cdd:cd06330 161 ALKKLKPDvEVVGELWPKlGATDYTAYITALLAAKPDGVFSSLWGGDLVTFVKQAKPYGLfdKTKVVSGL--GGGSEVLQ 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 244 AGGPQFTNGVLMT------FGKDPrtisEGKTVIEKFRA-SGFEPEGYTLYAYASIQAIAAAYNAVGADNTKA-SEWLKS 315
Cdd:cd06330 239 ALGKEMPEGLIGGgrypfgWPDTP----LNKAFVEAYRAkYGEYPTYWAYEAYAAVMALKAAIEKAGSTDTDKvIAALEG 314
|
....*....
gi 2294037010 316 HSVDTVMGK 324
Cdd:cd06330 315 LTFDTPGGK 323
|
|
| PBP1_ABC_HAAT-like |
cd06348 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-340 |
2.48e-49 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380571 [Multi-domain] Cd Length: 342 Bit Score: 168.57 E-value: 2.48e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06348 1 KIGVALSLTGPGALYGQSQKNGAQLAVEEINAAGGVGGVKIELIVEDTAGDPEQAINAFQKLINQDKVLAILGPTLSSEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGmKDMFRMCGRDDQqgAIAANYM--LDVLKAKKIAVIHD-KDTYGQGLADATR 166
Cdd:cd06348 81 FAADPIAQQAKVPVVGISNTAPGITDIG-PYIFRNSLPEDK--VIPPTVKaaKKKYGIKKVAVLYDqDDAFTVSGTKVFP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 167 AALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGg 246
Cdd:cd06348 158 AALKKNGVEVLDTETFQTGDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPDLIKLAG- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 247 pQFTNGVLMT---FGKDPRTISegKTVIEKFR-ASGFEPEGYTLYAYASIQAIAAAYNAVG-------ADNTKASEWLKS 315
Cdd:cd06348 237 -KAAEGVIVGsawSPDNPDPKN--QAFVAAYKeKYGKEPDQFAAQAYDAAYILAEAIKKAGsttdradLRDALARILIAK 313
|
330 340
....*....|....*....|....*
gi 2294037010 316 hSVDTVMGKKAWDGKGDLKVSDYVV 340
Cdd:cd06348 314 -DFEGPLGPFSFDADRDGIQPPVVL 337
|
|
| PBP1_ABC_ligand_binding-like |
cd06345 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-332 |
1.10e-47 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380568 [Multi-domain] Cd Length: 356 Bit Score: 164.75 E-value: 1.10e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTgpnASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06345 1 KIGVLGPLS---APAGEAMERGAELAVEEINAAGGILGRKVELVVADTQGKPEDGVAAAERLITEDKVDAIVGGFRSEVV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMKD------MFRMCGRDDQQGAIAANYMLDVLKA----KKIAVIHDKDTYGQ 159
Cdd:cd06345 78 LAAMEVAAEYKVPFIVTGAASPAITKKVKKDyekykyVFRVGPNNSYLGATVAEFLKDLLVEklgfKKVAILAEDAAWGR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 160 GLADATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFsGDCVVtee 239
Cdd:cd06345 158 GIAEALKKLLPEAGLEVVGVERFPTGTTDFTPILSKIKASGADVIVTIFSGPGGILLVKQWAELGVPAPLV-GINVP--- 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 240 lvttAGGPQF-------TNGVLMT---FGKDPRTiSEGKTVIEKFRA-SGFEPEGYTLYAYASIQAIAAAYNAVG-ADNT 307
Cdd:cd06345 234 ----AQDPEFwentggaGEYEITLafaAPKAKVT-PKTKPFVDAYKKkYGEAPNYTAYTAYDAIYILAEAIERAGsTDPD 308
|
330 340
....*....|....*....|....*
gi 2294037010 308 KASEWLKSHSVDTVMGKKAWDGKGD 332
Cdd:cd06345 309 ALVKALEKTDYEGVRGRIKFDKKDE 333
|
|
| PBP1_ABC_HAAT-like |
cd19985 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-233 |
2.03e-46 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380640 [Multi-domain] Cd Length: 321 Bit Score: 160.52 E-value: 2.03e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVsAVVGHFCSSST 89
Cdd:cd19985 1 HIAVVGPMSGKSASKGKSMLRGAELYIDQINAAGGINGKKVKLDVFDDQNDPDAARKAAQIIVSDKAL-AVIGHYYSSAS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITErgmkD---MFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATR 166
Cdd:cd19985 80 IAAGKIYKKAGIPAITPSATADAVTR----DnpwYFRVIFNDSLQGRFLANYAKKVLKKDKVSIIYEEDSYGKSLASVFE 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2294037010 167 AALAKRGTKEVLYEGLSRGEKDFNALVTKI-GALK-----PDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGD 233
Cdd:cd19985 156 ATARALGLKVLKKWSFDTDSSQLDQNLDQIvDELKkapdePGVIFLATHADEGAKLIKKLRDAGLKAPIIGPD 228
|
|
| PBP1_ABC_ligand_binding-like |
cd19982 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
10-296 |
4.64e-46 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380637 [Multi-domain] Cd Length: 302 Bit Score: 158.98 E-value: 4.64e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd19982 1 KIGAILSLTGPFAPFGEMFKNGYEMALEEINAAGGIKGKKLELVIEDDQSKPQTALAAAEKLVSQDKVPLIVGGYSSGIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd19982 81 LPVAAVAERQKIPLLVPTAADDDITKPGYKYVFRLNPPASIYAKALFDFFKELVKPKTIAILYENTAFGTSVAKAARRFA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGdcvvteelvtTAGG--- 246
Cdd:cd19982 161 KKRGIEVVADESYDKGATDFKPLLNKVKAANPDVVYMVSYLNDAILLMRQAKELGLNPKLFAG----------GGAGfti 230
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2294037010 247 PQFTNGV------LMTFG------KDPRTISEGKTVIEKFrasGFEPEGYTLYAYASIQAIA 296
Cdd:cd19982 231 PEFLKQAgplaeyVVTATlwspdvKYPGAKEFYEKYKAKY---GVEPSYHEAEAYAALYVAA 289
|
|
| PBP1_ABC_transporter_GPCR_C-like |
cd04509 |
Family C of G-protein coupled receptors and their close homologs, the type 1 ... |
10-229 |
5.47e-40 |
|
Family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems; This CD includes members of the family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems. The family C GPCR includes glutamate/glycine-gated ion channels such as the NMDA receptor, G-protein-coupled receptors, metabotropic glutamate, GABA-B, calcium sensing, pheromone receptors, and atrial natriuretic peptide-guanylate cyclase receptors. The glutamate receptors that form cation-selective ion channels, iGluR, can be classified into three different subgroups according to their binding-affinity for the agonists NMDA (N-methyl-D-asparate), AMPA (alpha-amino-3-dihydro-5-methyl-3-oxo-4-isoxazolepropionic acid), and kainate. L-glutamate is a major neurotransmitter in the brain of vertebrates and acts through either mGluRs or iGluRs. mGluRs subunits possess seven transmembrane segments and a large N-terminal extracellular domain. ABC-type leucine-isoleucine-valine binding protein (LIVBP) is a bacterial periplasmic binding protein that has homology with the amino-terminal domain of the glutamate-receptor ion channels (iGluRs). The extracellular regions of iGluRs are made of two PBP-like domains in tandem, a LIVBP-like domain that constitutes the N terminus (included in this model) followed by a domain related to lysine-arginine-ornithine-binding protein (LAOBP) that belongs to the type 2 periplasmic binding fold protein superfamily. The uncharacterized periplasmic components of various ABC-type transport systems are also included in this family.
Pssm-ID: 380490 Cd Length: 306 Bit Score: 143.21 E-value: 5.47e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTG----------PNASYGAQYWKGASQAVADINAAG-GIKGEKIVLVQGDDACEPKQAVAVANRLVDES--- 75
Cdd:cd04509 1 KVGVLFAVHGkgpsgvpcgdIVAQYGIQRFEAMEQALDDINADPnLLPNNTLGIVIYDDCCDPKQALEQSNKFVNDLiqk 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 76 -------------------GVSAVVGHFCSSSTMPASEVYDEAGILTITPGSTNP-LITERGMKDMFRMCGRDDQQGAIA 135
Cdd:cd04509 81 dtsdvrctngeppvfvkpeGIKGVIGHLCSSVTIPVSNILELFGIPQITYAATAPeLSDDRGYQLFLRVVPLDSDQAPAM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 136 ANYMLDvLKAKKIAVIHDKDTYGQGLADATRAALAKRGTKEVLYEGL--SRGEKDFNALVTKIGALKP-DVVYFGGCHPE 212
Cdd:cd04509 161 ADIVKE-KVWQYVSIVHDEGQYGEGGARAFQDGLKKGGLCIAFSDGItaGEKTKDFDRLVARLKKENNiRFVVYFGYHPE 239
|
250
....*....|....*..
gi 2294037010 213 AGPLVRQMREQGLQAKF 229
Cdd:cd04509 240 MGQILRAARRAGLVGKF 256
|
|
| PBP1_ABC_HAAT-like |
cd19983 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
10-296 |
2.62e-38 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380638 [Multi-domain] Cd Length: 303 Bit Score: 138.49 E-value: 2.62e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDEsGVSAVVGHFCSSST 89
Cdd:cd19983 1 RIGFVGGLTGRYSDLGVQGRNGAQLAVEEINAAGGINGRPVELIIRDDQQDPEAAKAADRELIAG-GVVAIIGHMTSAMT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITerGMKDMF-RMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKD--TYGQGLADATR 166
Cdd:cd19983 80 VAVLPVINEAKVLMISPTVSTPELS--GKDDYFfRVTPTTRESAQALARYAYNRGGLRRVAVIYDLSnrAYSESWLDNFR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 167 AALAKRG---TKEVLYEglSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTT 243
Cdd:cd19983 158 SEFEALGgriVAEIPFS--SGADVDFSDLARRLLASKPDGLLLVASAVDTAMLAQQIRKLGSKIPLFSSAWAATEELLEL 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2294037010 244 AGgpQFTNGVLMT-----FGKDPRTISEGKTVIEKFrasGFEPEGYTLYAYASIQAIA 296
Cdd:cd19983 236 GG--KAVEGMLFSqaydrNSSNPRYLAFKEAYEERF---GREPSFAAAYAYEAAMVLA 288
|
|
| PBP1_ABC_ligand_binding-like |
cd06326 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
9-256 |
4.11e-36 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380549 [Multi-domain] Cd Length: 339 Bit Score: 133.44 E-value: 4.11e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 9 VKIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSS 88
Cdd:cd06326 1 IVIGQSAPLSGPLAELGREYLAGAKAYFDQVNAAGGINGRKIRLVTLDDGYDPARTVENTRQLIEQDKVVALFGYVGTAN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 89 TMPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQ-GAIAANymLDVLKAKKIAVIHDKDTYGQGLADATRA 167
Cdd:cd06326 81 VEAVLPLLEEAGVPLVGPLTGADSLREPGNPYVFHVRASYADEvEKIVRH--LATLGLKRIAVVYQDDPFGKEGLAAAEA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 168 ALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDcVVTEELVTTAGGP 247
Cdd:cd06326 159 ALAARGLEPVATAAVARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFIKALRAAGGAAQFYGLS-VVGAAALAKALGD 237
|
....*....
gi 2294037010 248 QfTNGVLMT 256
Cdd:cd06326 238 A-ARGVVVS 245
|
|
| PBP1_ABC_ligand_binding-like |
cd19978 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
9-256 |
1.67e-34 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380633 [Multi-domain] Cd Length: 341 Bit Score: 129.23 E-value: 1.67e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 9 VKIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSS 88
Cdd:cd19978 1 IRLGMSAALSGPAAELGNEMKRGIEAAFNEVNAQGGVNGRKIKLIALDDGYEPDRTVKNTKKLIEEDKVFALIGYVGTPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 89 TMPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAA 168
Cdd:cd19978 81 ALAALPLANEKKIPLFGPFTGAEFLRTPFLPYVFNLRASYADETEALVDYLVKTLGPKRIAIFYQNDAFGLAGLEGAKKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRGTKEVL---YEglsRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAG 245
Cdd:cd19978 161 LKKRGLTPVAegsYT---RNTLDVEEALAKILKAKPEAIILVGTYAPAAEFIRLARAAGLNPLFANVSFVGSEALALELG 237
|
250
....*....|.
gi 2294037010 246 GpqFTNGVLMT 256
Cdd:cd19978 238 D--YGEGVIVS 246
|
|
| PBP1_AmiC-like |
cd06331 |
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ... |
10-309 |
1.25e-33 |
|
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380554 [Multi-domain] Cd Length: 333 Bit Score: 126.95 E-value: 1.25e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06331 1 KIGLLTPLSGPASVYGRAIANGAELAVEEINAAGGVLGRPVELVVEDDASDPATAVAAARRLIQQDKVDAIVGPITSATR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTItpgstNPLITERGM--KDMFRMCGRDDQQGAIAANYMLDvLKAKKIAVIHDKDTYGQGLADATRA 167
Cdd:cd06331 81 NAVAPVAERAKVPLL-----YPTFYEGGEcsPYLFCFGEVPNQQLDPLIPWLME-EYGKKFYLIGSDYVWPRTMNDAARR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 168 ALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGGP 247
Cdd:cd06331 155 VIEAHGGEVVGEEYLPLGTTDFSSVIEKIKASGADVVLSTLVGADAVTFLKQFAAAGLRRKVRIAALLFDENTLAGLGAE 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2294037010 248 QfTNGVLMTFG-----KDPrtisEGKTVIEKFRASgFEPEGYTLY-----AYASIQAIAAAYNAVGADNTKA 309
Cdd:cd06331 235 A-AEGIYSVLSyfqslDTP----ENKAFVAAYRKK-FGEDAPPITslseaAYEAVHLYAAAVEKAGSTDPEA 300
|
|
| PBP1_SBP-like |
cd19989 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
10-296 |
3.83e-32 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380644 [Multi-domain] Cd Length: 299 Bit Score: 122.00 E-value: 3.83e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd19989 1 KIGVLTPLSGPYAALGEEARRGAQLAVEEINAAGGILGRPVELVVEDTEGKPATAVQKARKLVEQDGVDFLTGAVSSAVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGS-TNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLkAKKIAVIHDKDTYGQGLADATRAA 168
Cdd:cd19989 81 LAVAPKAAELKVPYLVTVAaDDELTGENCNRYTFRVNTSDRMIARALAPWLAENG-GKKWYIVYADYAWGQSSAEAFKEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKF-FSGDCVVTEELVTTAGGP 247
Cdd:cd19989 160 IEELGGEVVGTLFAPLGTTDFSSYITQISDSGADGLLLALAGSDAVNFLKQAGQFGLGKKYkIVGGILSIEPLALPALGD 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 2294037010 248 qFTNGVLMTFGKDPrTIS--EGKTVIEKFRASGFEPEGYTLY-AYASIQAIA 296
Cdd:cd19989 240 -AAEGVYGGVRYPP-TLDtpANRAFVEAYEKEYGEAPDNFAGeAYEAMQALA 289
|
|
| PBP1_aromatic_compounds-like |
cd06332 |
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ... |
10-340 |
2.09e-25 |
|
type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.
Pssm-ID: 380555 [Multi-domain] Cd Length: 336 Bit Score: 104.60 E-value: 2.09e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINaaGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06332 1 KIGLLAPLTGPFAALGEDMVRGFELALEEVG--GEVAGRKVELVVEDDAGDPDTAVTKARKLVEQDKVDVLIGPLSGDEG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGM-KDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRAA 168
Cdd:cd06332 79 LAVAPYAKEPGVPFINPVAGADDLTQRAKaPNFFRTSFTGSQWSAPLGDYAYKELGYKKVATIGSDYAFGYEQAAGFKRG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRG---TKEVLYEGlsrGEKDFNALVTKIGALKpDVVYFGGCHPEAGPLVRQMREQGLQAK-FFSGDCVVTEELVTTA 244
Cdd:cd06332 159 FEAAGgevVQEIWVPL---GTTDFSPYIAQIPSAD-DAVFAFLGGADAVRFLKQYREFGLKDKiPLIGGGTTVDESVLPA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 245 GGPQFTNGVLMTFGKDPRTISEGKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVG---ADNTKASEWLKSHSVDT 320
Cdd:cd06332 235 MGDAALGIISASHYAEGLDNPENKKFVAAYKKKfGKLPSLYAAGGYDGAQAILEALEAVGgdvSDKQALAAALRKVKFDS 314
|
330 340
....*....|....*....|
gi 2294037010 321 VMGKKAWDGKGDLKVSDYVV 340
Cdd:cd06332 315 PRGPFSFDENRNPVQNVYIR 334
|
|
| PBP1_RPA0668_benzoate-like |
cd20014 |
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ... |
10-310 |
2.98e-24 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380667 [Multi-domain] Cd Length: 346 Bit Score: 101.54 E-value: 2.98e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINaaGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd20014 1 KIGLLLPYSGVYAALGEDIRNGFQLYLDEHG--GKLGGRPIELVKEDDEADPDVALQKARKLIEQDKVDVLVGPVSSGVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPG-STNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKaKKIAVIHDKDTYGQGLADATRAA 168
Cdd:cd20014 79 LAIRDVVEQAKVPLIVANaGANALTRAACSPYIFRTSFSNWQLGYALGKYAAENVG-KTVVTIASDYAAGREVVAGFKEG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRGTKeVLYEGLSR--GEKDFNALVTKIGALKPDVVY--FGGchPEAGPLVRQMREQGLQAKF-FSGDCVVTEELVTT 243
Cdd:cd20014 158 FEAAGGK-VVGEIWTPlgTTTDFSPYLTQIAASGPDAVYafFAG--ADAVRFVKQYAEFGLKGKIpLYGPGFLTDEDVLP 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2294037010 244 AGGPQFTNGVLMTFGKDPRTISEGKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVGADNTKAS 310
Cdd:cd20014 235 ALGEAAEGIITVLHYAPTLDNPANRAFVAAYQAKyGRLPDVYAVQGYDAAQVIDAALEAVGGDTSDKD 302
|
|
| PBP1_SBP-like |
cd19987 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
10-327 |
3.91e-23 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380642 [Multi-domain] Cd Length: 353 Bit Score: 98.56 E-value: 3.91e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAG------------GIKGEKIVLVQGDDACEPKQAVAVANRLVDESGV 77
Cdd:cd19987 1 TIGLNVPLSGPYAPQGEDQRRGFELAVDHLNNGGglvdkdsrlsgdGILGKKVELVTADTETKADTAVDNAKRLIEQDGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 78 SAVVGHFCSSSTMPASEVYDEAGIL---TITPgsTNPLITERGMKDMFRMCGRDDQQGAIAANYMLDVL-KAKKIAVIHD 153
Cdd:cd19987 81 VMITGGSSSAVAVAAQKLAQKEGVLyfaGLSH--SNDTTGKDCHRYGFRECFNAHMSAKALAPYLVEKFgKDRKYFYLTA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 154 KDTYGQGLADATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDV---VYFGGchpEAGPLVRQMREQGLQAKFf 230
Cdd:cd19987 159 DYTWGHSTEQSMREYTEAHGWKTVGNPATPLGETDFSAALLNAADSGADVlvlVLFGR---DMVNALKQAKQFGLLKKM- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 231 sgDCVV--TEELVTTAGGPQFTNGVLMTFGKDPR---TISEGKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVGA 304
Cdd:cd19987 235 --DIVVplLTAFMAESVGPEIMEGVLGTVNWHWSlpdDYSYAFGKAEAFEKEyGAYPSQAAASAYVQVLQYAAAVERAGS 312
|
330 340
....*....|....*....|....
gi 2294037010 305 -DNTKASEWLKSHSVDTVMGKKAW 327
Cdd:cd19987 313 fDPPAVIRALEGHEYTLLKGEQYW 336
|
|
| PBP1_SBP-like |
cd06329 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
10-309 |
2.74e-21 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380552 [Multi-domain] Cd Length: 343 Bit Score: 93.11 E-value: 2.74e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDE------SGVSAVVGH 83
Cdd:cd06329 1 KIAFIDPLSGPFASVGEIYLKGLQFAIEEINAGGGLLGRKIELVPFDNKGSPQEALIQLKKAIDQgirfvlQGNSSAVAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 84 FCSSSTMPASEVYDEAGILTITPGSTNPLITErgmKDM----FRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQ 159
Cdd:cd06329 81 ALIDAIEKHNQRNPDKRVLFLNYGAEAPELTG---AKCsfwhFRFDANADMKMAALADYMKKDGSIKKVYLINQDYSFGR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 160 GLADATRAALA-KRGTKEVLyeglsrGE--------KDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFF 230
Cdd:cd06329 158 DVAAAAKKNLKkKRPDIEIV------GEdlhplgkvKDFSPYIAKIKASGADTVITGNWGNDLTLLMKAARDSGLKAPFY 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 231 SgdCVVTEELVTTAGGPQFTNGVLMTF-----GKDPrtisEGKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVGA 304
Cdd:cd06329 232 T--YYADGPGAPAAIGEAGVGRLVAVAywhpnPKTP----ELEKFAEAFRAKyGRYPDFNIGRTYMGVEMLAAAIKKAGS 305
|
....*
gi 2294037010 305 DNTKA 309
Cdd:cd06329 306 TDPEK 310
|
|
| PBP1_alkylbenzenes-like |
cd06360 |
type 1 periplasmic binding component of active transport systems predicted be involved in ... |
10-349 |
6.43e-21 |
|
type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Pssm-ID: 380583 [Multi-domain] Cd Length: 357 Bit Score: 92.36 E-value: 6.43e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADI-NAAGGikgEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSS 88
Cdd:cd06360 1 KIGVLLPLTGPLAVNGEDVRDGFELYFDEIgNQVAG---RKIELIVEDDEGKPDVGLTKARKLVERDKVHVLAGIVSSAV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 89 TMPASEVYDEAGILTITPGST-NPLITERGMKDMFRMCGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGLADATRA 167
Cdd:cd06360 78 AYAVRDYVVEQKIPLVISNAGaAPLTQELASPYIFRTSFSNGQYDAPFGQYAYEKLGYRRIAVMASDYAAGHEQAGAFAR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 168 ALAKRGTKEV--LYEGLsrGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKF--FSGDCVVTEELVTT 243
Cdd:cd06360 158 TFKQAGGKVVqeIYPPL--GTADFAPYLARIQQDAADAVWAFFAGADAIRFVKQYDEYGLKGKLplVGIGGLVDDAILPE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 244 AGGPQF--TNGVLMTFGKDprtISEGKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVG---ADNTKASEWLKSHS 317
Cdd:cd06360 236 QGDAALgiVSYLHYSAALD---TPENKAFVQAYRKKyGRDPGLYAEGGYVAARAIAEALEAVKgnvEDKEAFLEALRKVR 312
|
330 340 350
....*....|....*....|....*....|..
gi 2294037010 318 VDTVMGKKAWDGKGDLKVSDYVVYAWDDKGKY 349
Cdd:cd06360 313 FEAPRGPFRFDPYQQAVVTTYIRRVEKVDGKL 344
|
|
| PBP1_ABC_ligand_binding-like |
cd06334 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
10-245 |
1.40e-20 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380557 [Multi-domain] Cd Length: 360 Bit Score: 91.15 E-value: 1.40e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHfCSSST 89
Cdd:cd06334 1 KIGLLTDLTGPTADVGKPYAQGVRDYLNYVNEEGGINGVKIELEECDTGYKVPRAVACYKRLKAQDGVVAILGW-GTGDT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGS---------TNPLItergmkdmFRMCGRDDQQGAIAANYMLD----VLKAKKIAVIHDKDT 156
Cdd:cd06334 80 EALAPRVAKDKIPYISASYgrsladdgkVFPYN--------FFVGATYSSQARALLKYIAQewggKLKGPKVAFVYHDSP 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 157 YGQGLADATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKF----FSG 232
Cdd:cd06334 152 FGREPIPALKAYAKELGFEVVAEQVPSPGALDATAQWLRIRRAGPDYVIIQGTGGSVAVIIKDAKRLGLKTKFigniWGG 231
|
250
....*....|...
gi 2294037010 233 DcvvtEELVTTAG 245
Cdd:cd06334 232 D----EDLIKLAG 240
|
|
| ANF_receptor |
pfam01094 |
Receptor family ligand binding region; This family includes extracellular ligand binding ... |
35-345 |
1.66e-20 |
|
Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
Pssm-ID: 460062 [Multi-domain] Cd Length: 347 Bit Score: 90.91 E-value: 1.66e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 35 AVADINAAGGI-KGEKIVLVQGDDACEPKQAVAVANRLVdESGVSAVVGHFCSSSTMPASEVYDEAGILTITPGSTNPLI 113
Cdd:pfam01094 9 AVEDINADPGLlPGTKLEYIILDTCCDPSLALAAALDLL-KGEVVAIIGPSCSSVASAVASLANEWKVPLISYGSTSPAL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 114 TERGMKDMF-RMCGRDDQQG-AIAAnyMLDVLKAKKIAVIHDKDTYGQGLADATRAALAKRG---TKEVLYEGLSRGEKD 188
Cdd:pfam01094 88 SDLNRYPTFlRTTPSDTSQAdAIVD--ILKHFGWKRVALIYSDDDYGESGLQALEDALRERGirvAYKAVIPPAQDDDEI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 189 FNALVTKIgALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFS---GDCVVTEELVTTAGGPQFTNGVLmTFgKDPRTIS 265
Cdd:pfam01094 166 ARKLLKEV-KSRARVIVVCCSSETARRLLKAARELGMMGEGYVwiaTDGLTTSLVILNPSTLEAAGGVL-GF-RLHPPDS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 266 EGKT--VIEKFRAS-------GFEPEGYTLYAYASIQAIAAAYNAVGADNTKAS---------------EWLKSHSVDTV 321
Cdd:pfam01094 243 PEFSefFWEKLSDEkelyenlGGLPVSYGALAYDAVYLLAHALHNLLRDDKPGRacgalgpwnggqkllRYLKNVNFTGL 322
|
330 340
....*....|....*....|....
gi 2294037010 322 MGKKAWDGKGDLKVSDYVVYAWDD 345
Cdd:pfam01094 323 TGNVQFDENGDRINPDYDILNLNG 346
|
|
| PBP1_ABC_ligand_binding-like |
cd06341 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
10-310 |
8.86e-20 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380564 [Multi-domain] Cd Length: 340 Bit Score: 88.90 E-value: 8.86e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFcSSST 89
Cdd:cd06341 1 KIGLIYPDTGPGAASFSAARAGAEARFGLANAAGGINGRKVEYVWCDDQSDPATNLQAARQLVEDEKVFALVGSS-SAAS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPlITERGMKDMFRMCGrdDQQGAIAANYMLDVLKAKKIAVI-HDKDTYGQGLADATRAA 168
Cdd:cd06341 80 GSANDYLAQAGIPVVGGAGVSV-WCFRNMFSNFFSLG--GGGSTTTYGQYAAALGGTKAAVVvTDIPAASQQLAQQLAAS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 LAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFSGDCVVTEELVTTAGgpQ 248
Cdd:cd06341 157 LRAAGVEVVGTAPYAAAAPDYTAVAQAAKAAGADAVVGVLDPDVAARVLKAARAQGLDLKVALSPSGYDPSVLAAYG--A 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 249 FTNGVLMTFGKDPRTisEGKTVIEKFRA--SGFEPE------GYTLYAYASIQAIAAAYNAVGADNTKAS 310
Cdd:cd06341 235 ALAGVSVASTFLPFE--ADTPAVKAYRAamAKYAPElqdplqQFALSGYIAADLFVRGLEAAGGCPTRAA 302
|
|
| PBP1_SBP-like |
cd06328 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
10-225 |
4.76e-18 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380551 [Multi-domain] Cd Length: 336 Bit Score: 83.89 E-value: 4.76e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKG-------ASQAVADINaaggikGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVG 82
Cdd:cd06328 1 KIGVITSLTGPLAAYGKQTERGfelgleyATDGTMEVD------GRKIEVIVKDDQGDPDTAKAAATELIGDDGVDILVG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 83 HFCSSSTMPASEVYDEAGILTITPGSTNPLITERGM-KDMFRMcGRDDQQGAIAANYMLDVLKAKKIAVIHDKDTYGQGL 161
Cdd:cd06328 75 TVSSAVALALAPVAEQNKKILIVGPAAADSITGENWnKYTFRT-SRNSWQDAIAGAKALADPLGKSVAFLAQDYAFGQDG 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2294037010 162 ADATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGL 225
Cdd:cd06328 154 VAAFKKALEAKGGKIVGEELVPVTTTDFTPYLQRILDAKPDVLFVAWAGTGALTLWQQLADQGV 217
|
|
| PBP1_ABC_ligand_binding-like |
cd19979 |
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ... |
10-231 |
8.92e-18 |
|
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380634 [Multi-domain] Cd Length: 350 Bit Score: 83.04 E-value: 8.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVG--Hfcss 87
Cdd:cd19979 1 VIGLDADLSGGSAASGEAIKRGIQLAIDEINAAGGLLGRKLELVAKDHRGNPARGVDNLREFAADPDVLAVFGglH---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 88 sTMPASEVYD---EAGILTITPGSTNPLITERGMKD--MFRMCGRDDQQGAIAANYMLDVlKAKKIAVIHDKDTYGQGLA 162
Cdd:cd19979 77 -SPVLLAELDfihELKIPYLVPWAAATPITRNGYSPnyIFRLSVDDSLAGPFLVEYALKK-GCKRPALLLENTGWGRSNL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2294037010 163 DATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKFFS 231
Cdd:cd19979 155 KAMTKALAKKGLQPVGVEWFNWGDTDAKPQLRALKAAGADAILLVANAPEGAAIVKALAALPERLPIIS 223
|
|
| PBP1_Nba-like |
cd06359 |
type 1 periplasmic binding component of active transport systems predicted to be involved in ... |
10-305 |
1.77e-15 |
|
type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.
Pssm-ID: 380582 [Multi-domain] Cd Length: 333 Bit Score: 76.14 E-value: 1.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINaaGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06359 1 KIGFITTLSGPAAVLGQDMRDGFNLALEQLG--GKLGGLPVEVVVEDDQLKPDVAKQAAERLIERDKVDFVTGIIFSNVM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGST-NPLITERGMKDMFRMCGRDDQQGAIAANYMLDvLKAKKIAVIHDKDTYGQGLADAtraa 168
Cdd:cd06359 79 LAVVKPVVDSKVFYISANAGpSDLAGKGCNPNFFVTSWQNDQLHEAAGKYAND-KGYKRVYLLAPNYQAGKDALAG---- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 169 lAKRGTK-EVLYEGLSR-GEKDFNALVTKIGALKPDVVYF---GGchpeAG-PLVRQMREQGLQAK------FFSGDCVV 236
Cdd:cd06359 154 -FKRTYKgEVVGEIYTPlGQLDFSAELAQIRAAKPDAVFAfypGG----MGvNFVKQYAQAGLKKKiplytvGTLDDEDL 228
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2294037010 237 TEELVTTAGG--------PQFTNgvlmtfgkdprtiSEGKTVIEKFRAS-GFEPEGYTLYAYASIQAIAAAYNAVGAD 305
Cdd:cd06359 229 LPAMGDAALGvlsvsqwsPDLDN-------------PENKRFVAAFRKKyGRPPSNYAAQGYDAALLIDAAVKAVGGD 293
|
|
| PBP1_NHase |
cd06358 |
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively ... |
10-205 |
3.54e-15 |
|
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides; This group includes the type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides, which are subsequently converted by amidases to yield free carboxylic acids and ammonia. NHases from bacteria and fungi have been purified and characterized. In Rhodococcus sp., the nitrile hydratase operon consists of six genes encoding NHase regulator 2, NHase regulator 1, amidase, NHase alpha subunit, NHase beta subunit, and NHase activator. The operon produces a constitutive hydratase that has a broad substrate spectrum: aliphatic and aromatic nitriles, mononitriles and dinitriles, hydroxynitriles and amino-nitriles, and a constitutive amidase of equally low substrate specificity. NHases are metalloenzymes containing either cobalt or iron, and therefore can be classified into two subgroups: ferric NHases and cobalt NHases.
Pssm-ID: 380581 [Multi-domain] Cd Length: 333 Bit Score: 75.32 E-value: 3.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06358 1 RIGLLIPLSGPAGLWGPSCEACAELAAAEINAAGGILGREVELVLIDAGGPPAEVAAAARRLVDDGAVDAIVGMHTSAVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASE--------VY--------DEAGILTItpGSTnplitergmkdmfrmcgrDDQQGAIAANYMLDVLKAKKIAVIHD 153
Cdd:cd06358 81 QALANavggrvpyVYtplyeggeRTPGVYAI--GET------------------PEEQLRPALRWLADERRVRRWFLVGN 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2294037010 154 KDTYGQGLADATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVY 205
Cdd:cd06358 141 DYVWPRASHAAARRYIARLGGEVVGERFVPLGEDDFERVLARIRASRPDAVL 192
|
|
| PBP1_YraM_LppC_lipoprotein-like |
cd06339 |
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ... |
10-226 |
5.24e-15 |
|
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).
Pssm-ID: 380562 [Multi-domain] Cd Length: 331 Bit Score: 75.00 E-value: 5.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINaaggikGEKIVLVQGDDAcEPKQAVAVANRLVDEsGVSAVVGHFCSSST 89
Cdd:cd06339 1 RIALLLPLSGPYAAAGQAIRDGIELALFDAG------GSRPELRVYDTG-GPEGAAAAYQQAVAE-GADLIIGPLLKSSV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMkdmFRMCGRDDQQGAIAANYMLDVLKaKKIAVIHDKDTYGQGLADATRAAL 169
Cdd:cd06339 73 AALAAAAQALGVPVLALNNDESATAGPGL---FQFGLSPEDEARQAARYAVQQGL-RRFAVLAPDNAYGQRVANAFREAW 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2294037010 170 AKRGTKEVLYEGLSRGEKDFNALVTKIGAL----------------------KPDVVYFGGCHPEAGPLVRQMREQGLQ 226
Cdd:cd06339 149 QALGGTVVAVESYDPDETDFSAAIRRLLGVdqsearirqlgellefeprrrqDFDAIFLPAGPEQARLIAPQLAFYGAG 227
|
|
| PBP1_SBP-like |
cd20378 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
10-309 |
6.04e-15 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380668 [Multi-domain] Cd Length: 357 Bit Score: 75.07 E-value: 6.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVAdinAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd20378 1 TLGGLVSMSGAFAAAGKLADRGMRLAVE---EYGGALGRPLKYITRDTEGKPGTGVRKVQEAIAQDGARFFIGGTLSSVA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGSTNPLITERGMKDMFRMCGrdDQQGAIAAN--YMLDVL-KAKKIAVIHDKDTYGQGLADATR 166
Cdd:cd20378 78 LAVSEEAEKAGGVYITSGGADEITGSRCNRSTFRWSV--PTYGAIRQTvrPVIKAMpKAKRWYTITPQYVFGESLLKNAK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 167 AALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKffsgdcvVTEELVTTAG- 245
Cdd:cd20378 156 EVLKEKGIEHVGNSYHSLGEREFSGYLTKAMAARPDVLLILNFGSQAVDALRQAVSFGLKRK-------MKILVAWSSGl 228
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2294037010 246 ------GPQFTNGVLMTFGKDPRTISEG-KTVIEKFRASGFEPEGYTL-YAYASIQAIAAAYNAVGADNTKA 309
Cdd:cd20378 229 dqfqelGPDICEGVYFGAQYWHDVDTPAnKALVKVYQAKFKETPSYALaAGYACTRMLLDAIDKAGSTDPAA 300
|
|
| PBP1_FmdD-like |
cd06355 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
35-228 |
3.72e-13 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380578 [Multi-domain] Cd Length: 347 Bit Score: 69.53 E-value: 3.72e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 35 AVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSSTMPASEVYDEAGILTItpgstNPLIT 114
Cdd:cd06355 26 AIDEINAAGGLLGRKIEPVIEDGASDWPTFAEKAEKLITQDKVAVIFGCWTSASRKAVLPVIEKYNGLLF-----YPVQY 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 115 ErGM---KDMFRMCGRDDQQGAIAANYMLDVLkAKKIAVIHDKDTYGQGLADATRAALAKRGTKEVLYEGLSRGEKDFNA 191
Cdd:cd06355 101 E-GLeqsPNIVYTGATPNQQILPAIDWLLENL-GKRFFLVGSDYVFPRTANKIIRDQLKALGGEVVGEEYVPLGGTDFDA 178
|
170 180 190
....*....|....*....|....*....|....*....
gi 2294037010 192 LVTKIGALKPDVVY--FGGCHPEAgpLVRQMREQGLQAK 228
Cdd:cd06355 179 IVAKIKAFKPDVIVntLNGDSNIA--FFKQLAAAGITAS 215
|
|
| PBP1_amide_urea_BP-like |
cd06356 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
10-205 |
1.00e-11 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the type 1 periplasmic-binding proteins that are predicted to have a function similar to that of an active transport system for short chain amides and/or urea in bacteria and Archaea, by sequence comparison and phylogenetic analysis.
Pssm-ID: 380579 [Multi-domain] Cd Length: 334 Bit Score: 65.01 E-value: 1.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSST 89
Cdd:cd06356 1 KIGSIFDLSGGLNIYGKPMVHAMKLAVEEINAAGGLLGRQIELVAYDTQSDMQKYTQYAQQLILRDKVDVVFGGITSASR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 90 MPASEVYDEAGILTITPGstnplITERGMKDMFRMC-GRD-DQQGAIAANYMLDVLkAKKIAVIHDKDTYGQGLADATRA 167
Cdd:cd06356 81 EAIRPILRRNKILYFYNT-----QYEGGVCDKNTFCtGSTpEQQVSPLIEWAIKKY-GKKVYIIAADYNFGQISADWVKK 154
|
170 180 190
....*....|....*....|....*....|....*...
gi 2294037010 168 ALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVY 205
Cdd:cd06356 155 YAKKNGGEVVGEEFFPLDVTDFGPTIQKIQAAKPDFVV 192
|
|
| PBP1_SBP-like |
cd06327 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
10-327 |
2.96e-11 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380550 [Multi-domain] Cd Length: 336 Bit Score: 63.74 E-value: 2.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQ-AVADinAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSS 88
Cdd:cd06327 1 RIGVLTDLSGVYADLSGPGSVEAAKmAVED--FGGKVLGRPIEVVSADHQNKPDVASAIAREWYDRDGVDAIVDVPNSAV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 89 TMPASEVYDEAGILTITPGSTNPLITERGmkdmfrmCGRDDQQ-----GAIAANYMLDVLKA--KKIAVIHDKDTYGQGL 161
Cdd:cd06327 79 ALAVQKLAKEKKKIAIVTGAGSSDLTGKA-------CSPYGVHwaydtYALARGTVKALVKQggKSWFFITADYAFGHSL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 162 ADATRAALAKRGTKEVlyeGLSR---GEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAKffsGDCVVTE 238
Cdd:cd06327 152 EADATAAVKAAGGKVV---GSVRhplGTTDFSSFLLQAQASGADVIALANAGADLVNAVKQAREFGLTDG---GQKLAAL 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 239 ELVTT---AGGPQFTNGVLMT----FGKDPRTISEGKTVIEKFrasGFEPEGYTLYAYASI----QAIAAAynavGADNT 307
Cdd:cd06327 226 LLFITdihALGLDAAQGLYLTtafyWDRDDATRAWAKRFFART---GKMPTMLQAGVYSAVlhylKAVKAA----GTDDA 298
|
330 340
....*....|....*....|.
gi 2294037010 308 KA-SEWLKSHSVDTVMGKKAW 327
Cdd:cd06327 299 DAvVAKMREMPVNDFFAKNGR 319
|
|
| Peripla_BP_5 |
pfam13433 |
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ... |
9-228 |
4.52e-11 |
|
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins.
Pssm-ID: 463875 [Multi-domain] Cd Length: 363 Bit Score: 63.38 E-value: 4.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 9 VKIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSS 88
Cdd:pfam13433 1 IKVGVLHSLTGTMAISERSLKDATLMAIEEINAAGGVLGRKIEPVVVDPASDWPLFAEKARKLIDQDKVRVVFGCWTSAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 89 TMPASEVYDEAGILTITpgstnPLITErGM---KDMFRMCGRDDQQGAIAANYMLDVLKaKKIAVIHDKDTYGQGLADAT 165
Cdd:pfam13433 81 RKAVLPVFERHNGLLFY-----PVQYE-GFessRNIFYTGAAPNQQAIPAVDYLLSELG-KRFFLVGSDYVYPRTTNRIL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2294037010 166 RAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYFGGCHPEAGPLVRQMREQGLQAK 228
Cdd:pfam13433 154 RAYLKAKGGEVVGERYLPLGSSDWQSIVAKIKAAGPDVVFSTINGDSNVAFYRALRAAGITAE 216
|
|
| PBP1_AmiC |
cd06357 |
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ... |
10-205 |
1.40e-10 |
|
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.
Pssm-ID: 380580 [Multi-domain] Cd Length: 357 Bit Score: 61.83 E-value: 1.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSS- 88
Cdd:cd06357 1 RVGLLFSQTGVTAIIEQSMLNGALLAIEEINAAGGVNGRPIEPVVYDPASDPDRYRELAERLLLEDGVRHIFGCYTSASr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 89 --TMPASEVYDeaGIL---TITPG---STNpLItergmkdmfrMCGRDDQQGAIA-ANYMLDVLKaKKIAVIHDKDTYGQ 159
Cdd:cd06357 81 kaVLPVVERHN--ALLwypTPYEGfeySPN-VI----------YTGAVPNQHLLPlARYLLAHFG-KRVFLVGSNYVYPW 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2294037010 160 GLADATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVY 205
Cdd:cd06357 147 ESNRVARELIEASGGEVVGERYVPLGDTDFAEIIEEIKSLKPDVVF 192
|
|
| PBP1_RPA0985_benzoate-like |
cd20013 |
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the ... |
10-228 |
1.79e-10 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0985 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0985 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380666 [Multi-domain] Cd Length: 356 Bit Score: 61.50 E-value: 1.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQAVADinAAGGIKGEKIVLVQGDDA-CEPKQAVAVANRLVDESGVSAVVGHFCSSS 88
Cdd:cd20013 1 KVGVIGPFSGPFADYGKQFDRGIDLYLKL--HGDKVGGRKVEVIYRDDGgPNPAVAKRLAQELIVRDKVQILIGFGFTPN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 89 TMPASEVYDEAGILTITPGSTNPLITERGmKDMFRMCGRDDQQGAIAANYMLDvlKAKKIAVIHDKDtYGQGL--ADATR 166
Cdd:cd20013 79 ALAVAPVATEAKTPTVIMNAATSSITRKS-PYFVRTSFTMWQVAYPMGKWAAK--NGIKKAYTAVAD-YAPGHdaETAFK 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2294037010 167 AALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVYF---GGchPEAGPLVRQMREQGLQAK 228
Cdd:cd20013 155 KAFEAAGGKIVGSIRVPLATPDFAPFMQRIKDAKPDAVFVfvpAG--APSIGFLKAYAERGLKEA 217
|
|
| PBP1_GPCR_family_C-like |
cd06350 |
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory ... |
72-295 |
8.19e-10 |
|
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate; categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (m; Ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate and are categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs). The metabotropic glutamate receptors (mGluR) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. The mGluRs are coupled to G proteins and are thus distinct from the iGluRs which internally contain ligand-gated ion channels. The mGluR structure is divided into three regions: the extracellular region, the seven-spanning transmembrane region and the cytoplasmic region. The extracellular region is further divided into the ligand-binding domain (LBD) and the cysteine-rich domain. The LBD has sequence similarity to the LIVBP, which is a bacterial periplasmic protein (PBP), as well as to the extracellular region of both iGluR and the gamma-aminobutyric acid (GABA)b receptor. iGluRs are divided into three main subtypes based on pharmacological profile: NMDA, AMPA, and kainate receptors. All family C GPCRs have a large extracellular N terminus that contain a domain with homology to bacterial periplasmic amino acid-binding proteins.
Pssm-ID: 380573 Cd Length: 350 Bit Score: 59.62 E-value: 8.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 72 VDESGVSAVVGHFCSSSTMPASEVYDEAGILTITPGSTNPLITERGMKDMF-RMCGRDDQQG-AIAAnyMLDVLKAKKIA 149
Cdd:cd06350 90 IGPPNIVAVIGAASSSVSIAVANLLGLFKIPQISYASTSPELSDKIRYPYFlRTVPSDTLQAkAIAD--LLKHFNWNYVS 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 150 VIHDKDTYGQGLADATRAALAKRG-----TKEVLYEGLsrgEKDFNALVTKIGALKPD--VVYFGGCHpEAGPLVRQMRE 222
Cdd:cd06350 168 TVYSDDDYGRSGIEAFEREAKERGiciaqTIVIPENST---EDEIKRIIDKLKSSPNAkvVVLFLTES-DARELLKEAKR 243
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2294037010 223 QGLQAKFFSGDCVVTEELVTTAGGPQFTNGVLmtfgkdprTISEGKTVIEKFRasgfepEGYTLYAYASIQAI 295
Cdd:cd06350 244 RNLTGFTWIGSDGWGDSLVILEGYEDVLGGAI--------GVVPRSKEIPGFD------DYLKSYAPYVIDAV 302
|
|
| PBP1_glutamate_receptors-like |
cd06269 |
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl ... |
35-205 |
6.75e-07 |
|
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as natriuretic peptide receptors (NPRs), and N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of ionotropic glutamate rece; This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs), and the N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the ionotropic glutamate receptors, all of which are structurally similar and related to the periplasmic-binding fold type 1 family. The family C GPCRs consists of metabotropic glutamate receptor (mGluR), a calcium-sensing receptor (CaSR), gamma-aminobutyric acid receptor (GABAbR), the promiscuous L-alpha-amino acid receptor GPR6A, families of taste and pheromone receptors, and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids, ions, and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors, AMPA receptors, and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B), the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E, GC-F), and olfactory receptors (GC-D and GC-G).
Pssm-ID: 380493 [Multi-domain] Cd Length: 332 Bit Score: 50.49 E-value: 6.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 35 AVADINAAGGI-KGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSSTMPASEVYDEAGILTITPGSTNPLI 113
Cdd:cd06269 25 ALSDVNSRPDLlPKTTLGLAIRDSECNPTQALLSACDLLAAAKVVAILGPGCSASAAPVANLARHWDIPVLSYGATAPGL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 114 TERGMKDMFRMCGRDDqqgAIAANYMLDVLKA---KKIAVIHDKDTYGQGLADATRAALAKRGTKEV-LYEGLSRGEKDF 189
Cdd:cd06269 105 SDKSRYAYFLRTVPPD---SKQADAMLALVRRlgwNKVVLIYSDDEYGEFGLEGLEELFQEKGGLITsRQSFDENKDDDL 181
|
170
....*....|....*.
gi 2294037010 190 NALVTKIGALKPDVVY 205
Cdd:cd06269 182 TKLLRNLRDTEARVII 197
|
|
| PBP1_GABAb_receptor |
cd06366 |
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for ... |
11-301 |
1.92e-06 |
|
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA); Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380589 [Multi-domain] Cd Length: 404 Bit Score: 49.17 E-value: 1.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 11 IGVAGPFTGPNASY-GAQYWKGASQAVADINAAGGI-KGEKIVLVQGDDACEPKQAVavaNRLVD----ESGVSAVVGHF 84
Cdd:cd06366 2 IGGLFPLSGSKGWWgGAGILPAAEMALEHINNRSDIlPGYNLELIWNDTQCDPGLGL---KALYDllytPPPKVMLLGPG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 85 CSSSTMPASEVYDEAGILTITPGSTNPLITERGM-KDMFRMCGRDDQQGA--IAanyMLDVLKAKKIAVIHDKDTYGQGL 161
Cdd:cd06366 79 CSSVTEPVAEASKYWNLVQLSYAATSPALSDRKRyPYFFRTVPSDTAFNParIA---LLKHFGWKRVATIYQNDEVFSST 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 162 ADATRAALAKRGTKEVLYEGLSRGEkdfnaLVTKIGALK-PDV-VYFGGCHPEAGPLV-RQMREQGLQAK----FFSG-- 232
Cdd:cd06366 156 AEDLEELLEEANITIVATESFSSED-----PTDQLENLKeKDArIIIGLFYEDAARKVfCEAYKLGMYGPkyvwILPGwy 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 233 ------------DCVVtEELVTTAGGpQFTNGVLMTFGKDPRTISeGKTV-------IEKFRASGFEPEGYTLYAYASIQ 293
Cdd:cd06366 231 ddnwwdvpdndvNCTP-EQMLEALEG-HFSTELLPLNPDNTKTIS-GLTAqeflkeyLERLSNSNYTGSPYAPFAYDAVW 307
|
....*...
gi 2294037010 294 AIAAAYNA 301
Cdd:cd06366 308 AIALALNK 315
|
|
| PBP1_ABC_ligand_binding-like |
cd06337 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
10-228 |
2.01e-05 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380560 [Multi-domain] Cd Length: 354 Bit Score: 45.75 E-value: 2.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAqYWKGASQAVADINAAGGIK--GEK--IVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFC 85
Cdd:cd06337 1 KIGRVSPLTGPLAAFGE-ADPWVLEQIREAFADGGIKvgGKKypVEIVVRDSQSDPNRAGEAARDLILRDKVDLMLASGT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 86 SSSTMPASEVYDEAG---ILTITPgsTNPLITERG--MKDMFRMC-----GRDDqqgaIAANY--MLDVLKA-KKIAVIH 152
Cdd:cd06337 80 PDTVNPVADQCEANGvpcISTDAP--WQAWFFGRGgdPAKGFKWTfhffwGLED----IAANFlgMWDQVPTnKVVGLLW 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2294037010 153 DKDTYGQGLADATRAALAKRGTKEVLYEGLSRGEKDFNALVTKIGALKPDVVyFGGCH-PEAGPLVRQMREQGLQAK 228
Cdd:cd06337 154 PNDPDGTAFADAFLGLPAAAGYTLVDPGRFPPGTDDFSSIINAFKKAGVEIV-TGVMIpPDFATFWRQAAQQGFKPK 229
|
|
| PBP1_GABAb_receptor_plant |
cd19990 |
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close ... |
35-175 |
5.54e-05 |
|
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants; This group includes the ligand-binding domain of Arabidopsis thaliana glutamate receptors, which have sequence similarity with animal ionotropic glutamate receptor and its close homologs in other plants. The ligand-binding domain of GABAb receptors are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380645 [Multi-domain] Cd Length: 373 Bit Score: 44.53 E-value: 5.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 35 AVADINAAGGIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSSSTMPASEVYDEAGILTITPGSTNPLIT 114
Cdd:cd19990 23 AVSDFNSDSSSYGTKLVLHVRDSKGDPLQAASAALDLIKNKKVEAIIGPQTSEEASFVAELGNKAQVPIISFSATSPTLS 102
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2294037010 115 ERGMKDMFRMCGRDDQQ-GAIAAnyMLDVLKAKKIAVIHDKDTYGQGLADATRAALAKRGTK 175
Cdd:cd19990 103 SLRWPFFIRMTHNDSSQmKAIAA--IVQSYGWRRVVLIYEDDDYGSGIIPYLSDALQEVGSR 162
|
|
| PBP1_NPR_GC-like |
cd06352 |
ligand-binding domain of membrane guanylyl-cyclase receptors; Ligand-binding domain of ... |
10-179 |
1.81e-04 |
|
ligand-binding domain of membrane guanylyl-cyclase receptors; Ligand-binding domain of membrane guanylyl-cyclase receptors. Membrane guanylyl cyclases (GC) have a single membrane-spanning region and are activated by endogenous and exogenous peptides. This family can be divided into three major subfamilies: the natriuretic peptide receptors (NPRs), sensory organ-specific membrane GCs, and the enterotoxin/guanylin receptors. The binding of peptide ligands to the receptor results in the activation of the cytosolic catalytic domain. Three types of NPRs have been cloned from mammalian tissues: NPR-A/GC-A, NPR-B/ GC-B, and NPR-C. In addition, two of the GCs, GC-D and GC-G, appear to be pseudogenes in humans. Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are produced in the heart, and both bind to the NPR-A. NPR-C, also termed the clearance receptor, binds each of the natriuretic peptides and can alter circulating levels of these peptides. The ligand binding domain of the NPRs exhibits strong structural similarity to the type 1 periplasmic binding fold protein family.
Pssm-ID: 380575 [Multi-domain] Cd Length: 391 Bit Score: 43.11 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 10 KIGVAGPFTGPNASYGAQYWKGASQ-AVADINAAG-GIKGEKIVLVQGDDACEPKQAVAVANRLVDESGVSAVVGHFCSS 87
Cdd:cd06352 1 KVGVLAPSNSQSLPVGYARSAPAIDiAIERINSEGlLLPGFNFEFTYRDSCCDESEAVGAAADLIYKRNVDVFIGPACSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 88 STMPASEV---YDeagILTITPGSTNPLITERGMKDMF-RMCGRDDQQGaIAANYMLDVLKAKKIAVIHDKDT-YGQGLA 162
Cdd:cd06352 81 AADAVGRLatyWN---IPIITWGAVSASFLDKSRYPTLtRTSPNSLSLA-EALLALLKQFNWKRAAIIYSDDDsKCFSIA 156
|
170
....*....|....*..
gi 2294037010 163 DATRAALAKRGTKEVLY 179
Cdd:cd06352 157 NDLEDALNQEDNLTISY 173
|
|
| PBP1_mGluR |
cd06362 |
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of ... |
77-196 |
8.22e-04 |
|
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of the metabotropic glutamate receptors (mGluR), which are members of the family C of G-protein-coupled receptors that transduce extracellular signals into G-protein activation and ultimately into cellular responses. mGluRs bind to glutamate and function as an excitatory neurotransmitter; they are involved in learning, memory, anxiety, and the perception of pain. Eight subtypes of mGluRs have been cloned so far, and are classified into three groups according to their sequence similarities, transduction mechanisms, and pharmacological profiles. Group I is composed of mGlu1R and mGlu5R that both stimulate PLC hydrolysis. Group II includes mGlu2R and mGlu3R, which inhibit adenylyl cyclase, as do mGlu4R, mGlu6R, mGlu7R, and mGlu8R, which form group III.
Pssm-ID: 380585 [Multi-domain] Cd Length: 460 Bit Score: 41.12 E-value: 8.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294037010 77 VSAVVGHFCSSSTMPASEVYDEAGILTITPGSTNPLITERGMKDMF-RMCGRDDQQgaiaANYMLDVLKA---KKIAVIH 152
Cdd:cd06362 108 VVGVIGAESSSVSIQVANLLRLFKIPQISYASTSDELSDKERYPYFlRTVPSDSFQ----AKAIVDILLHfnwTYVSVVY 183
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2294037010 153 DKDTYGQGLADATRAALAKRGT----KEVLYEglSRGEKDFNALVTKI 196
Cdd:cd06362 184 SEGSYGEEGYKAFKKLARKAGIciaeSERISQ--DSDEKDYDDVIQKL 229
|
|
| |
