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Conserved domains on  [gi|2294038205|ref|WP_259225186|]
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MULTISPECIES: autotransporter assembly complex protein TamA [Raoultella]

Protein Classification

autotransporter assembly complex protein TamA( domain architecture ID 11432556)

autotransporter assembly complex protein TamA is part of the translocation and assembly module (TAM) complex which functions in translocating autotransporters across the outer membrane

CATH:  3.10.20.310
Gene Ontology:  GO:0097347|GO:0009306
SCOP:  4006413|4006144
TCDB:  1.B.33

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TamA COG0729
Outer membrane translocation and assembly module TamA [Cell wall/membrane/envelope biogenesis]; ...
 7-577 0e+00

Outer membrane translocation and assembly module TamA [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440493 [Multi-domain]  Cd Length: 574  Bit Score: 646.57  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205   7 LCVTSLLLVSGVASAASVRLQVEGLSGELQKNVRARLSTIQSDEVTPD-----RRFRARVDDAIREGLKALGYYEPTIDF 81
Cdd:COG0729     1 LLLLLALLLAAPAAAAPYEVEIDGLDGELRDNLRAHLSLLRLRDEPDLdpaelRRLARADPERIRAALRAEGYYSPTVTI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205  82 DLRPPPakGRQVLIAKVTPGEPVRIGGTDVILRGGARTDRDYLDLLKTRP-AIGTVLNHGDYDGFKSSLTRVALRKGYFD 160
Cdd:COG0729    81 RLDGRD--GPWTVTITVDPGPPVRIGKVDIELLGEAAQDPARRKLLAAWPlKPGDPLRHGAYEAAKSALLDALRERGYPD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 161 SEFNKSQLGVSLDRHQAFWDIDYNSGERYRFGAVTFSG-SQIRDEYLQNLVPFKQGDEYTSEDLAELNRRLAATGWFSSV 239
Cdd:COG0729   159 ARFTQSRAEVDPATNTADVTLTVDSGPRYRFGEITVEGlSRVPEDFLRRLAPFKPGEPYSPDKLLELQQRLQSTGYFSSV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 240 VVAPEFEKsRKTKVLPLKGVVAPRKENTVETGVGYSTDVGPRVKATWRKPWMNSYGHSLTSSLSLSAPEQQVDFSYKVPL 319
Cdd:COG0729   239 RVTPDEDP-APDGTVPVTVTLTERKRRRIGFGLGYSTDTGPRLSAGWEHRNLFGRGHRLRLELELSQPEQSLSADYRIPP 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 320 LKsPLEQYYLMQGGFKRTDLNDTKADSTTLGASRFWEMSSGWQRAINLRWSLDHFTQANVTNTTMLIYPGVSVNRTRSRG 399
Cdd:COG0729   318 LF-PLGQYLSLGAGLEREDTDDYDSRSLTLGAGRTRRLSDGWTRSLGLRLLYERFTDGDDDRTYTLLSPGLSWTRDRRDD 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 400 GLMPTWGDSQRYSVDYSNTMWGSDINFVVAQAQEVWIRTLYDRHRFVVRGNLGWIEADNFDKVPPDLRFFAGGDRSIRGY 479
Cdd:COG0729   397 PLDPTRGYRLSLELGPGSKLLGSDTSFLRLYARGSWYRPLGERHRLAGRAELGAILGADFDDVPPSLRFFAGGDGSVRGY 476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 480 KYKSISPKDDDGKLIGASKLATGSLEYQYNVSGKWWGAMFVDGGEAVSDIRRSDFKTGAGVGVRWQSPVGPIKLDIAAPV 559
Cdd:COG0729   477 GYQSLGPRDGDGDVIGGRSLAVGSLEYRYRVTENWGLAVFVDAGNAFNDFPFSDLKVGAGLGLRWYSPVGPIRLDLAYPL 556

                         570
                  ....*....|....*...
gi 2294038205 560 GDKDEHGLQFYIGLGPEL 577
Cdd:COG0729   557 NDRDDSSFRLYISLGQAF 574
 
Name Accession Description Interval E-value
TamA COG0729
Outer membrane translocation and assembly module TamA [Cell wall/membrane/envelope biogenesis]; ...
 7-577 0e+00

Outer membrane translocation and assembly module TamA [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440493 [Multi-domain]  Cd Length: 574  Bit Score: 646.57  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205   7 LCVTSLLLVSGVASAASVRLQVEGLSGELQKNVRARLSTIQSDEVTPD-----RRFRARVDDAIREGLKALGYYEPTIDF 81
Cdd:COG0729     1 LLLLLALLLAAPAAAAPYEVEIDGLDGELRDNLRAHLSLLRLRDEPDLdpaelRRLARADPERIRAALRAEGYYSPTVTI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205  82 DLRPPPakGRQVLIAKVTPGEPVRIGGTDVILRGGARTDRDYLDLLKTRP-AIGTVLNHGDYDGFKSSLTRVALRKGYFD 160
Cdd:COG0729    81 RLDGRD--GPWTVTITVDPGPPVRIGKVDIELLGEAAQDPARRKLLAAWPlKPGDPLRHGAYEAAKSALLDALRERGYPD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 161 SEFNKSQLGVSLDRHQAFWDIDYNSGERYRFGAVTFSG-SQIRDEYLQNLVPFKQGDEYTSEDLAELNRRLAATGWFSSV 239
Cdd:COG0729   159 ARFTQSRAEVDPATNTADVTLTVDSGPRYRFGEITVEGlSRVPEDFLRRLAPFKPGEPYSPDKLLELQQRLQSTGYFSSV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 240 VVAPEFEKsRKTKVLPLKGVVAPRKENTVETGVGYSTDVGPRVKATWRKPWMNSYGHSLTSSLSLSAPEQQVDFSYKVPL 319
Cdd:COG0729   239 RVTPDEDP-APDGTVPVTVTLTERKRRRIGFGLGYSTDTGPRLSAGWEHRNLFGRGHRLRLELELSQPEQSLSADYRIPP 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 320 LKsPLEQYYLMQGGFKRTDLNDTKADSTTLGASRFWEMSSGWQRAINLRWSLDHFTQANVTNTTMLIYPGVSVNRTRSRG 399
Cdd:COG0729   318 LF-PLGQYLSLGAGLEREDTDDYDSRSLTLGAGRTRRLSDGWTRSLGLRLLYERFTDGDDDRTYTLLSPGLSWTRDRRDD 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 400 GLMPTWGDSQRYSVDYSNTMWGSDINFVVAQAQEVWIRTLYDRHRFVVRGNLGWIEADNFDKVPPDLRFFAGGDRSIRGY 479
Cdd:COG0729   397 PLDPTRGYRLSLELGPGSKLLGSDTSFLRLYARGSWYRPLGERHRLAGRAELGAILGADFDDVPPSLRFFAGGDGSVRGY 476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 480 KYKSISPKDDDGKLIGASKLATGSLEYQYNVSGKWWGAMFVDGGEAVSDIRRSDFKTGAGVGVRWQSPVGPIKLDIAAPV 559
Cdd:COG0729   477 GYQSLGPRDGDGDVIGGRSLAVGSLEYRYRVTENWGLAVFVDAGNAFNDFPFSDLKVGAGLGLRWYSPVGPIRLDLAYPL 556

                         570
                  ....*....|....*...
gi 2294038205 560 GDKDEHGLQFYIGLGPEL 577
Cdd:COG0729   557 NDRDDSSFRLYISLGQAF 574
OM_YaeT TIGR03303
outer membrane protein assembly complex, YaeT protein; Members of this protein family are the ...
 64-572 1.02e-35

outer membrane protein assembly complex, YaeT protein; Members of this protein family are the YaeT protein of the YaeT/YfiO complex for assembling proteins into the outer membrane of Gram-negative bacteria. This protein is similar in sequence and function to a non-essential paralog, YtfM, that is also in the Omp85 family. Members of this family typically have five tandem copies of the surface antigen variable number repeat (pfam07244), followed by an outer membrane beta-barrel domain (pfam01103), while the YtfM family typically has a single pfam07244 repeat. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274514 [Multi-domain]  Cd Length: 741  Bit Score: 142.72  E-value: 1.02e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205  64 AIREGLKALGYYEPTIDFDLRPPPaKGRQVLIAKVTPGEPVRIGGTDVIlrgGAR--TDRDYLDLLKTRPAI-------G 134
Cdd:TIGR03303 111 ALKEFYRSRGKYNAKVEAKVTPLP-RNRVDLEFNIKEGKKAKIKKINFV---GNKafSDSELRDVFALKESNfwswftgD 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 135 TVLNHGDYDGFKSSLTRVALRKGYFDSEFNKSQLGVSLDRHQAFWDIDYNSGERYRFGAVTFSG-SQIRDEYLQNLVPFK 213
Cdd:TIGR03303 187 DKYSKQKLEADLELLRSFYLNRGYLDFKVESTQVSITPDKKGVYITYNIKEGEQYKFGEVTIEGdLIGPDEELKKLLKIK 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 214 QGDEYTSEDLAE----LNRRLAATGwFSSVVVAPEFEKSRKTKVLPLKGVVAPRK------------------------- 264
Cdd:TIGR03303 267 KGEVFNRSKVTKivkaIKDLLGEKG-YAFANVNPRPQINDENKTVDLTFKVDPGKrvyvrrinisgntrtrdevirrelr 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 265 --------------------------ENTVET-------------------------GVGYSTDVGPRVKATWRKP-WMN 292
Cdd:TIGR03303 346 qlegdwyslskikrskrrlerlgyfeTVNIETvpvgspdqvdlnvkvkeqptgsisfGVGYGSSSGLSFNASISERnFLG 425

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 293 SyGHSLTSSLSLSAPEQQVDFSYkvpllkspLEQYYLM----QGG------FKRTDLNDTKADSTTLGASrfweMSSGWQ 362
Cdd:TIGR03303 426 T-GNRLSLSANKSSLSTSYSLSF--------TDPYFTDdgvsLGFsifyseTDRNYKNFSDYKTKTYGGS----INLGYP 492

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 363 RAINLRWSL-------------DHFTQANV-------TNTTMLIYPGVSVNRTRSRggLMPTWGDSQRYSVDYsnTMWGS 422
Cdd:TIGR03303 493 ITEYLRVSLgygyeqnkikddsDSDSSASYfikeqggKFIDSSLSYGWSYDTLDSG--YFPTKGSIQRLSQEF--AGPGG 568

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 423 DINFVVAQAQEVWIRTLYDRHRFV--VRGNLGWIEADNFDKVPPDLRFFAGGDRSIRGYKYKSISPKD--DDGKLIGASK 498
Cdd:TIGR03303 569 DLKYYKLTYDSEYYIPLSKEDDWVlsLRGRLGYGNGYGGKDLPFYERFYAGGIGSVRGFESNGIGPRDinDSGDSIGGNA 648

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 499 LATGSLEYQYNVSG-----KWWGAMFVDGGeAVSDIRR---------SDFKTGAGVGVRWQSPVGPIKLDIAAPVGDKD- 563
Cdd:TIGR03303 649 MATANVELIFPLPFlpednGLRGSVFFDAG-NVWGTDQkkegdysddSSLRASVGVGLRWISPMGPLRFSYAKPLKKKKg 727

                         650
                  ....*....|.
gi 2294038205 564 --EHGLQFYIG 572
Cdd:TIGR03303 728 dkTQSFQFSIG 738
Omp85 pfam01103
Omp85 superfamily domain; The Omp85 protein superfamily contains bacterial outer membrane ...
 380-573 2.33e-30

Omp85 superfamily domain; The Omp85 protein superfamily contains bacterial outer membrane proteins, which can function as protein translocases or as membrane protein assembly factors. The family includes the membrane bound beta barrel of proteins such as BamA and TamA from E. coli.


Pssm-ID: 460065 [Multi-domain]  Cd Length: 319  Bit Score: 121.31  E-value: 2.33e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 380 TNTTMLIYPGVSVNrTRSRGgLMPTWGDSQRYSVDYSNTMWGSDINFVVAQAQEVWIRTLYDRHRFVV--RGNLGWIEAD 457
Cdd:pfam01103 110 KSLTFSLSYGWTYD-TRDDG-LFPTRGSYLKFNLEFTGPFLGGDVSYYKLTADGSYYYPLGKDDSFVLsaRVALGYLDGY 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 458 NFDKVPPDLRFFAGGDRSIRGYKYKSISPKDDDGKLIGASKLATGSLEYQY----NVSGKWWGAMFVDGG---------- 523
Cdd:pfam01103 188 GTKDLPFYERFYAGGSNSVRGFEYGGIGPRDEDGDALGGNSYVVASLELRFplpfVPKQSVRGVLFFDAGnvwntgstdp 267

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2294038205 524 -EAVSDIRRSDFKTGAGVGVRWQSPVGPIKLDIAAPVGDKDE-HGLQFYIGL 573
Cdd:pfam01103 268 gSSRGARSKAGIRASVGVGLRWLSPLGPLRFDYAFPLKKPDGdETQRFQFGI 319
PRK11067 PRK11067
outer membrane protein assembly factor YaeT; Provisional
 400-572 3.94e-09

outer membrane protein assembly factor YaeT; Provisional


Pssm-ID: 236834 [Multi-domain]  Cd Length: 803  Bit Score: 59.68  E-value: 3.94e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 400 GLMPTWGDSQRysVDYSNTMWGSDINFVVAQAQEVWIRTLYDRHRFVV--RGNLGWieADNFD--KVPPDLRFFAGGDRS 475
Cdd:PRK11067  583 GYFPTAGNRVN--LTGKVTIPGSDNEYYKVTLDTAQYVPLDDDHKWVLlgRGRLGY--GDGLGgkEMPFYENFYAGGSST 658

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 476 IRGYKYKSISPK-------------DDDGKL------IGASKLATGSLE-----------YQYNVSGkwwgAMFVDGG-- 523
Cdd:PRK11067  659 VRGFQSNTIGPKavyypgqasnytqDGAKDLcksddaVGGNAMAVASLElitptpfisdkYANSVRT----SFFWDMGtv 734

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2294038205 524 -------------EAVSDIRR-SDFKTGAGVGVRWQSPVGPIKLDIAAPV----GDKDEHgLQFYIG 572
Cdd:PRK11067  735 wdtnwdntaytraAGYPDYSDpSNIRMSAGIALQWMSPLGPLVFSYAQPFkkydGDKAEQ-FQFNIG 800
 
Name Accession Description Interval E-value
TamA COG0729
Outer membrane translocation and assembly module TamA [Cell wall/membrane/envelope biogenesis]; ...
 7-577 0e+00

Outer membrane translocation and assembly module TamA [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440493 [Multi-domain]  Cd Length: 574  Bit Score: 646.57  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205   7 LCVTSLLLVSGVASAASVRLQVEGLSGELQKNVRARLSTIQSDEVTPD-----RRFRARVDDAIREGLKALGYYEPTIDF 81
Cdd:COG0729     1 LLLLLALLLAAPAAAAPYEVEIDGLDGELRDNLRAHLSLLRLRDEPDLdpaelRRLARADPERIRAALRAEGYYSPTVTI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205  82 DLRPPPakGRQVLIAKVTPGEPVRIGGTDVILRGGARTDRDYLDLLKTRP-AIGTVLNHGDYDGFKSSLTRVALRKGYFD 160
Cdd:COG0729    81 RLDGRD--GPWTVTITVDPGPPVRIGKVDIELLGEAAQDPARRKLLAAWPlKPGDPLRHGAYEAAKSALLDALRERGYPD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 161 SEFNKSQLGVSLDRHQAFWDIDYNSGERYRFGAVTFSG-SQIRDEYLQNLVPFKQGDEYTSEDLAELNRRLAATGWFSSV 239
Cdd:COG0729   159 ARFTQSRAEVDPATNTADVTLTVDSGPRYRFGEITVEGlSRVPEDFLRRLAPFKPGEPYSPDKLLELQQRLQSTGYFSSV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 240 VVAPEFEKsRKTKVLPLKGVVAPRKENTVETGVGYSTDVGPRVKATWRKPWMNSYGHSLTSSLSLSAPEQQVDFSYKVPL 319
Cdd:COG0729   239 RVTPDEDP-APDGTVPVTVTLTERKRRRIGFGLGYSTDTGPRLSAGWEHRNLFGRGHRLRLELELSQPEQSLSADYRIPP 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 320 LKsPLEQYYLMQGGFKRTDLNDTKADSTTLGASRFWEMSSGWQRAINLRWSLDHFTQANVTNTTMLIYPGVSVNRTRSRG 399
Cdd:COG0729   318 LF-PLGQYLSLGAGLEREDTDDYDSRSLTLGAGRTRRLSDGWTRSLGLRLLYERFTDGDDDRTYTLLSPGLSWTRDRRDD 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 400 GLMPTWGDSQRYSVDYSNTMWGSDINFVVAQAQEVWIRTLYDRHRFVVRGNLGWIEADNFDKVPPDLRFFAGGDRSIRGY 479
Cdd:COG0729   397 PLDPTRGYRLSLELGPGSKLLGSDTSFLRLYARGSWYRPLGERHRLAGRAELGAILGADFDDVPPSLRFFAGGDGSVRGY 476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 480 KYKSISPKDDDGKLIGASKLATGSLEYQYNVSGKWWGAMFVDGGEAVSDIRRSDFKTGAGVGVRWQSPVGPIKLDIAAPV 559
Cdd:COG0729   477 GYQSLGPRDGDGDVIGGRSLAVGSLEYRYRVTENWGLAVFVDAGNAFNDFPFSDLKVGAGLGLRWYSPVGPIRLDLAYPL 556

                         570
                  ....*....|....*...
gi 2294038205 560 GDKDEHGLQFYIGLGPEL 577
Cdd:COG0729   557 NDRDDSSFRLYISLGQAF 574
BamA COG4775
Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis];
25-574 5.49e-60

Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443807 [Multi-domain]  Cd Length: 711  Bit Score: 211.87  E-value: 5.49e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205  25 RLQVEGLSGELQKNVRARLSTIQSDEVTPDRRF-RARVD---DAIREGLKALGYYEPTIDFD-LRPPPAKGRQVLIAKVT 99
Cdd:COG4775   148 KINFVGNKAFSDKELRKVLKTKESGWLTKSDKYsKEKLEadlERLRSFYLNRGYLDARVDSTqVELSPDKKDIYITINIE 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 100 PGEPVRIGgtDVILRGGARTDRDYLDLLKTRPaiGTVLNHGDYDGFKSSLTRVALRKGYFDSEFNkSQLGVSLDRHQAFW 179
Cdd:COG4775   228 EGEQYKVG--DIKFEGNLVDEEELRKLLKIKP--GDVYNREKLEKDIEAITDLYGDNGYAFARVE-PVPEIDPENDTVDL 302

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 180 DIDYNSGERYRFGAVTFSG-SQIRDEYLQNLVPFKQGDEYTSEDLAELNRRLAATGWFSSVVVAPEFEKSRKTKVlPLKG 258
Cdd:COG4775   303 TFRIDEGPRVYVDRIEIEGnTRTRDEVIRRELRLKEGDPFSREKLERSRRRLYRLGYFESVDVETEPGPSTPDQV-DLVV 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 259 VVAPRKENTVETGVGYSTDVGPRVKATWRKPWMNSYGHSLTSSLSLSAPEQQVDFSYKVP-LLKSPLeqYYLMQGGFKRT 337
Cdd:COG4775   382 DVKEKPTGSLSLGAGYSSDDGFIGGASLSQRNLLGTGQELSLSLQLGSYSQSYSLSFTEPyFFGSPL--SLGVSLFYRRR 459

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 338 DLNDTKA-DSTTLGAS--------RFWEMSSGWQ----RAINLRWSLDHFTQANVTNTTMLIYPGVSVNRTRSRggLMPT 404
Cdd:COG4775   460 DASDYSSyDLKRTGGGlglgyplsEDLRLSLGYGyertDISDVDSSPDYLPDQNGSSNTSSLGLGLTYDTRDNP--LFPT 537

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 405 WGDSQRYSVDYSNTMWGSDINFVVAQAQEVWIRTLYDRHRFVVRGNLGWIEADNfDKVPPDLRFFAGGDRSIRGYKYKSI 484
Cdd:COG4775   538 RGSYLSLSLEFAGPYLGGDLEYYKLSADARYYFPLGKKLVLALRAEAGYLGGYG-KDLPFFERFYLGGFGSLRGYEENSL 616

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 485 SPKdddgklIGASKLATGSLEYQY----NVSGKWWGAMFVDGG---EAVSDIRRSDFKTGAGVGVRWQSPVGPIKLDIAA 557
Cdd:COG4775   617 GPR------LGGNAYLLGSAELRFplplPPSAGLRGALFVDAGnvwDSGDDFDLSDLRYSAGVGLRWDTPLGPLRLDYAY 690

                         570
                  ....*....|....*...
gi 2294038205 558 PVGDKD-EHGLQFYIGLG 574
Cdd:COG4775   691 PLDKEPgDSGQRFHFSIG 708
OM_YaeT TIGR03303
outer membrane protein assembly complex, YaeT protein; Members of this protein family are the ...
 64-572 1.02e-35

outer membrane protein assembly complex, YaeT protein; Members of this protein family are the YaeT protein of the YaeT/YfiO complex for assembling proteins into the outer membrane of Gram-negative bacteria. This protein is similar in sequence and function to a non-essential paralog, YtfM, that is also in the Omp85 family. Members of this family typically have five tandem copies of the surface antigen variable number repeat (pfam07244), followed by an outer membrane beta-barrel domain (pfam01103), while the YtfM family typically has a single pfam07244 repeat. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274514 [Multi-domain]  Cd Length: 741  Bit Score: 142.72  E-value: 1.02e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205  64 AIREGLKALGYYEPTIDFDLRPPPaKGRQVLIAKVTPGEPVRIGGTDVIlrgGAR--TDRDYLDLLKTRPAI-------G 134
Cdd:TIGR03303 111 ALKEFYRSRGKYNAKVEAKVTPLP-RNRVDLEFNIKEGKKAKIKKINFV---GNKafSDSELRDVFALKESNfwswftgD 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 135 TVLNHGDYDGFKSSLTRVALRKGYFDSEFNKSQLGVSLDRHQAFWDIDYNSGERYRFGAVTFSG-SQIRDEYLQNLVPFK 213
Cdd:TIGR03303 187 DKYSKQKLEADLELLRSFYLNRGYLDFKVESTQVSITPDKKGVYITYNIKEGEQYKFGEVTIEGdLIGPDEELKKLLKIK 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 214 QGDEYTSEDLAE----LNRRLAATGwFSSVVVAPEFEKSRKTKVLPLKGVVAPRK------------------------- 264
Cdd:TIGR03303 267 KGEVFNRSKVTKivkaIKDLLGEKG-YAFANVNPRPQINDENKTVDLTFKVDPGKrvyvrrinisgntrtrdevirrelr 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 265 --------------------------ENTVET-------------------------GVGYSTDVGPRVKATWRKP-WMN 292
Cdd:TIGR03303 346 qlegdwyslskikrskrrlerlgyfeTVNIETvpvgspdqvdlnvkvkeqptgsisfGVGYGSSSGLSFNASISERnFLG 425

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 293 SyGHSLTSSLSLSAPEQQVDFSYkvpllkspLEQYYLM----QGG------FKRTDLNDTKADSTTLGASrfweMSSGWQ 362
Cdd:TIGR03303 426 T-GNRLSLSANKSSLSTSYSLSF--------TDPYFTDdgvsLGFsifyseTDRNYKNFSDYKTKTYGGS----INLGYP 492

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 363 RAINLRWSL-------------DHFTQANV-------TNTTMLIYPGVSVNRTRSRggLMPTWGDSQRYSVDYsnTMWGS 422
Cdd:TIGR03303 493 ITEYLRVSLgygyeqnkikddsDSDSSASYfikeqggKFIDSSLSYGWSYDTLDSG--YFPTKGSIQRLSQEF--AGPGG 568

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 423 DINFVVAQAQEVWIRTLYDRHRFV--VRGNLGWIEADNFDKVPPDLRFFAGGDRSIRGYKYKSISPKD--DDGKLIGASK 498
Cdd:TIGR03303 569 DLKYYKLTYDSEYYIPLSKEDDWVlsLRGRLGYGNGYGGKDLPFYERFYAGGIGSVRGFESNGIGPRDinDSGDSIGGNA 648

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 499 LATGSLEYQYNVSG-----KWWGAMFVDGGeAVSDIRR---------SDFKTGAGVGVRWQSPVGPIKLDIAAPVGDKD- 563
Cdd:TIGR03303 649 MATANVELIFPLPFlpednGLRGSVFFDAG-NVWGTDQkkegdysddSSLRASVGVGLRWISPMGPLRFSYAKPLKKKKg 727

                         650
                  ....*....|.
gi 2294038205 564 --EHGLQFYIG 572
Cdd:TIGR03303 728 dkTQSFQFSIG 738
Omp85 pfam01103
Omp85 superfamily domain; The Omp85 protein superfamily contains bacterial outer membrane ...
 380-573 2.33e-30

Omp85 superfamily domain; The Omp85 protein superfamily contains bacterial outer membrane proteins, which can function as protein translocases or as membrane protein assembly factors. The family includes the membrane bound beta barrel of proteins such as BamA and TamA from E. coli.


Pssm-ID: 460065 [Multi-domain]  Cd Length: 319  Bit Score: 121.31  E-value: 2.33e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 380 TNTTMLIYPGVSVNrTRSRGgLMPTWGDSQRYSVDYSNTMWGSDINFVVAQAQEVWIRTLYDRHRFVV--RGNLGWIEAD 457
Cdd:pfam01103 110 KSLTFSLSYGWTYD-TRDDG-LFPTRGSYLKFNLEFTGPFLGGDVSYYKLTADGSYYYPLGKDDSFVLsaRVALGYLDGY 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 458 NFDKVPPDLRFFAGGDRSIRGYKYKSISPKDDDGKLIGASKLATGSLEYQY----NVSGKWWGAMFVDGG---------- 523
Cdd:pfam01103 188 GTKDLPFYERFYAGGSNSVRGFEYGGIGPRDEDGDALGGNSYVVASLELRFplpfVPKQSVRGVLFFDAGnvwntgstdp 267

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2294038205 524 -EAVSDIRRSDFKTGAGVGVRWQSPVGPIKLDIAAPVGDKDE-HGLQFYIGL 573
Cdd:pfam01103 268 gSSRGARSKAGIRASVGVGLRWLSPLGPLRFDYAFPLKKPDGdETQRFQFGI 319
POTRA_TamA_1 pfam17243
POTRA domain TamA domain 1; This family represents the POTRA domain found in the membrane ...
 25-100 2.59e-24

POTRA domain TamA domain 1; This family represents the POTRA domain found in the membrane insertase TamA.


Pssm-ID: 435807 [Multi-domain]  Cd Length: 74  Bit Score: 96.51  E-value: 2.59e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2294038205  25 RLQVEGLSGELQKNVRARLSTIQSDEVTPDRRFRARVDDAIREGLKALGYYEPTIDFDLRPPPakGRQVLIAKVTP 100
Cdd:pfam17243   1 EVEIKGVDGELLDNVRAYLSLLPERDDDGSERLHRQAEEQIRKALQALGYYQPTIEFELEEDD--GCWTLTLTVDP 74
PRK11067 PRK11067
outer membrane protein assembly factor YaeT; Provisional
 400-572 3.94e-09

outer membrane protein assembly factor YaeT; Provisional


Pssm-ID: 236834 [Multi-domain]  Cd Length: 803  Bit Score: 59.68  E-value: 3.94e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 400 GLMPTWGDSQRysVDYSNTMWGSDINFVVAQAQEVWIRTLYDRHRFVV--RGNLGWieADNFD--KVPPDLRFFAGGDRS 475
Cdd:PRK11067  583 GYFPTAGNRVN--LTGKVTIPGSDNEYYKVTLDTAQYVPLDDDHKWVLlgRGRLGY--GDGLGgkEMPFYENFYAGGSST 658

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 476 IRGYKYKSISPK-------------DDDGKL------IGASKLATGSLE-----------YQYNVSGkwwgAMFVDGG-- 523
Cdd:PRK11067  659 VRGFQSNTIGPKavyypgqasnytqDGAKDLcksddaVGGNAMAVASLElitptpfisdkYANSVRT----SFFWDMGtv 734

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2294038205 524 -------------EAVSDIRR-SDFKTGAGVGVRWQSPVGPIKLDIAAPV----GDKDEHgLQFYIG 572
Cdd:PRK11067  735 wdtnwdntaytraAGYPDYSDpSNIRMSAGIALQWMSPLGPLVFSYAQPFkkydGDKAEQ-FQFNIG 800
POTRA pfam07244
Surface antigen variable number repeat; This family is found primarily in bacterial surface ...
 190-254 2.29e-06

Surface antigen variable number repeat; This family is found primarily in bacterial surface antigens, normally as variable number repeats at the N-terminus. The C-terminus of these proteins is normally represented by pfam01103. The alignment centres on a -GY- or -GF- motif. Some members of this family are found in the mitochondria. It is predicted to have a mixed alpha/beta secondary structure.


Pssm-ID: 462121 [Multi-domain]  Cd Length: 78  Bit Score: 45.41  E-value: 2.29e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2294038205 190 RFGAVTFSGSQ-IRDEYLQNLVPFKQGDEYTSEDLAE----LNRRLAATGWFSSVVVA-PEFEKSRKTKVL 254
Cdd:pfam07244   1 KIGDINFEGNKkTKDEELRRLLGLKEGDVYNREKLEEdkeaLKDRYGRLGYFDASVSTnVEIDDEVNTVDL 71
FhaC COG2831
Hemolysin activation/secretion protein [Intracellular trafficking, secretion, and vesicular ...
 309-563 7.88e-06

Hemolysin activation/secretion protein [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442079 [Multi-domain]  Cd Length: 547  Bit Score: 48.80  E-value: 7.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 309 QQVDFSYKVPLLKSPLEQYYLmQGGFKRTDLNDTKADSTTLGASRFwemssgwQRAINLRWSLDHFTQANVTNTTMLIYP 388
Cdd:COG2831   305 QTYGLRLSYPLIRSRDQKLSL-SLGLDYKDSRNYLLGTEIEVQRRR-------LSVLRLGLSYTRRLGGGVLSLSLSFSQ 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 389 GVSvnrtrsrgglmptWGDSQrysvDYSNTMWGSDINFVVAQAQEVWIRTLYDRHRFVVRGNLGWieadNFDKVPPDLRF 468
Cdd:COG2831   377 GLD-------------WLGAT----PAPDASRGPDGRFTKLRLSASRVQPLPQDFSLLLRLDGQY----SSDPLLSSEQF 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2294038205 469 FAGGDRSIRGYkyksispkdDDGKLIGASKLAtGSLEYQYNV-----SGKWWGAMFVDGGE-----AVSDIRRSDFKTGA 538
Cdd:COG2831   436 SLGGRYSVRGY---------DEGELSGDNGWY-LSNELRWPLprlslLGGLQLYAFLDAGRvwnnsALPGQLNGRTLAGA 505

                         250       260
                  ....*....|....*....|....*...
gi 2294038205 539 GVGVRWQspVGP---IKLDIAAPVGDKD 563
Cdd:COG2831   506 GLGLRLS--LGKnlsLDLDYARPLGDPD 531
BamA COG4775
Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis];
191-244 1.04e-03

Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443807 [Multi-domain]  Cd Length: 711  Bit Score: 42.00  E-value: 1.04e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2294038205 191 FGAVTFSGSQ-IRDEYLQNLVPFKQGDEYTSEDLAELNRRLAATGWFSSVVVAPE 244
Cdd:COG4775     1 IKDIRVEGLQrVEAGTVLSYLPLRVGDTFDDEKLDEAIKALYATGLFSDVRIERE 55
LPD38 pfam18857
Large polyvalent protein associated domain 38; This is an alpha and beta fold domain found in ...
 195-244 6.60e-03

Large polyvalent protein associated domain 38; This is an alpha and beta fold domain found in polyvalent proteins of phages and prophages.


Pssm-ID: 465888  Cd Length: 190  Bit Score: 38.14  E-value: 6.60e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2294038205 195 TFSGSQIRDEYLQNLVPFKQGDEYTSE---DLAELNRRLAATGWFSSVVVAPE 244
Cdd:pfam18857  97 NFTGAPIVPERLENLPPSLQYTESTSElskAIGEALNDATGDYEPGSIDVSPE 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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