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Conserved domains on  [gi|2294150752|ref|WP_259273617|]
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MULTISPECIES: small membrane protein [Klebsiella]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
KPN_two_small super family cl41475
small membrane protein; Members of this family, including paralogs KPN_01023 and KPN_01923 ...
2-31 8.36e-06

small membrane protein; Members of this family, including paralogs KPN_01023 and KPN_01923 from Klebsiella pneumoniae subsp. pneumoniae MGH 78578, are small proteins, typically 40 amino acids in length. A highly hydrophobic region, about 25 amino acids in length with a composition typical of transmembrane segments, is followed by a highly basic region of about 15 amino acids. Analogous proteins of similar size, with apparently similar hydrophobic regions, have been described as membrane-associated proteins expressed in response to various types of cell envelope stress.


The actual alignment was detected with superfamily member NF033853:

Pssm-ID: 411421  Cd Length: 37  Bit Score: 36.78  E-value: 8.36e-06
                         10        20        30
                 ....*....|....*....|....*....|
gi 2294150752  2 LCIFFFSISVYSFISYLKDRRRQKLTFNDK 31
Cdd:NF033853   8 VAIFLLGVSVYSLISYIKDRRKTKLPFNKR 37
 
Name Accession Description Interval E-value
KPN_two_small NF033853
small membrane protein; Members of this family, including paralogs KPN_01023 and KPN_01923 ...
2-31 8.36e-06

small membrane protein; Members of this family, including paralogs KPN_01023 and KPN_01923 from Klebsiella pneumoniae subsp. pneumoniae MGH 78578, are small proteins, typically 40 amino acids in length. A highly hydrophobic region, about 25 amino acids in length with a composition typical of transmembrane segments, is followed by a highly basic region of about 15 amino acids. Analogous proteins of similar size, with apparently similar hydrophobic regions, have been described as membrane-associated proteins expressed in response to various types of cell envelope stress.


Pssm-ID: 411421  Cd Length: 37  Bit Score: 36.78  E-value: 8.36e-06
                         10        20        30
                 ....*....|....*....|....*....|
gi 2294150752  2 LCIFFFSISVYSFISYLKDRRRQKLTFNDK 31
Cdd:NF033853   8 VAIFLLGVSVYSLISYIKDRRKTKLPFNKR 37
 
Name Accession Description Interval E-value
KPN_two_small NF033853
small membrane protein; Members of this family, including paralogs KPN_01023 and KPN_01923 ...
2-31 8.36e-06

small membrane protein; Members of this family, including paralogs KPN_01023 and KPN_01923 from Klebsiella pneumoniae subsp. pneumoniae MGH 78578, are small proteins, typically 40 amino acids in length. A highly hydrophobic region, about 25 amino acids in length with a composition typical of transmembrane segments, is followed by a highly basic region of about 15 amino acids. Analogous proteins of similar size, with apparently similar hydrophobic regions, have been described as membrane-associated proteins expressed in response to various types of cell envelope stress.


Pssm-ID: 411421  Cd Length: 37  Bit Score: 36.78  E-value: 8.36e-06
                         10        20        30
                 ....*....|....*....|....*....|
gi 2294150752  2 LCIFFFSISVYSFISYLKDRRRQKLTFNDK 31
Cdd:NF033853   8 VAIFLLGVSVYSLISYIKDRRKTKLPFNKR 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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