|
Name |
Accession |
Description |
Interval |
E-value |
| T4SS-DNA_transf |
pfam02534 |
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and ... |
120-568 |
1.13e-90 |
|
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.
Pssm-ID: 367119 [Multi-domain] Cd Length: 468 Bit Score: 288.53 E-value: 1.13e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 120 SFTLDGD-------EKEGIIVGLKDKKIIRYVGA----------AFSAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKR 182
Cdd:pfam02534 1 RWANDGDlesagllTRENTIIGDVYTKDPDAWYAggllntdgdfSHVLVFAGTGSGKGVGVVIPNLLVWKGSIVVLDPKG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 183 ECFNITSLIRRVILRqEVFKFDPFSSVTH-RFNPLFYVSMGTSEGFNQLENLALIVYPYKTDGADAGsyLNKTAGSLFKS 261
Cdd:pfam02534 81 ELWELTSGIREKQGR-KVFVLEPFNPKTSdRYNPLDYIDRGSEQETEDILKVASLIMPGKGGGRDDF--FNNTARQLLVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 262 LavtlWFMIAKDKQALKELDIEPLfsmskinLLFERADPENLLSFLSEIRGD-LKGKEKTLVdigVSGLKAFIEMEDKTK 340
Cdd:pfam02534 158 L----IALVLRSKPTRTIGQTLRF-------VRNMLSEPNLIENKELAVLLNeLDGSHHDRV---GDNLRFYVNKTDETR 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 341 AQLKSNFLNGLSPFSNPNVAKATDGNDFDLRQVRKKRMTVYFCISGDNARLAEKVTNIFFQLAIQVNLEKMPTDDPEIKH 420
Cdd:pfam02534 224 SSVIGTAVSELALYADPEVRNATSGSDFDLRDLRRDKTSVYVILNPKDLTVVSPLLRVFFQMVVELLYLKLPNGDGRPKE 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 421 dCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSAS-DVKDARELSEAM 499
Cdd:pfam02534 304 -VLFLLDEFPSLGKLEILEEALATIRGYGIRLTTICQSISQLKETYGGEGAKSILSNHAVVICFAASnDEETAKYISKLL 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2304598917 500 GTKTVTIGSKSKSRSRGGMSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYMNEYF 568
Cdd:pfam02534 383 GKTTVEVESSSKSTDAKGSSRSRSISEVQRPLLTPDEVLRMPDDEQIVITKGQPPIKCKKALYFKDEDF 451
|
|
| VirD4 |
COG3505 |
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ... |
153-563 |
6.61e-79 |
|
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain] Cd Length: 402 Bit Score: 255.29 E-value: 6.61e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 153 AGTRAGKGAGIVITNLMKYW--WSVIILDPKRECFNITSLIRRvILRQEVFKFDPFSSV-THRFNPLFYVsmgtsEGFNQ 229
Cdd:COG3505 6 GPTGSGKTVGLVIPNLTQLArgESVVVTDPKGDLAELTAGFRR-RAGYDVYVFDPFDPErSHRWNPLDEI-----RDPAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 230 LENLALIVYPYKTDGADAGSYLNKTAGSLFKSLavtLWFMIAKDKQALKELdieplfsmskinllferadPENLLSFLSE 309
Cdd:COG3505 80 AQELAEALIPALGGGGGGDPFWREAARALLAAL---ILALAEEGRRTLADV-------------------YRLLSEPEEE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 310 IRGDLKGKEKTLVDIGVSGLKAFIEMEDKTKAQLKSNFLNGLSPFSNPNVAKATDGNDFDLRQVRKKRMTVYFCISGDNA 389
Cdd:COG3505 138 LRELLEALPESPHPPVADTLAAFLNAAEKTRSSVLSTLASALELLSDPEVAALTSGSDFDLRDLIREKGTLYLVLPPDDL 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 390 RLAEKVTNIFFQLAIQVNLEKMPTDDPEiKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYA 469
Cdd:COG3505 218 STLAPLLRLLLSQLIRALLRRAERSGRL-PRPVLLLLDEFANLGRLPSLETLLATGRGYGIRLVLILQSLAQLEAIYGEE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 470 GSKTLLASAPCKIVYSASDVKDARELSEAMGTKTVTigSKSKSRSRGgmSRSESESLIERPLVTTNELLTLKFSEEILAM 549
Cdd:COG3505 297 GAETILGNCGTKIFLGVNDPETAEYLSELLGKRTVE--RRSESRSRG--SRSRSRSEQERPLLTPDELRRLPDGEAIVLV 372
|
410
....*....|....
gi 2304598917 550 KGENPIRCEKAFYY 563
Cdd:COG3505 373 RGGPPIRAKKIRYY 386
|
|
| PRK13897 |
PRK13897 |
type IV secretion system component VirD4; Provisional |
1-587 |
3.07e-48 |
|
type IV secretion system component VirD4; Provisional
Pssm-ID: 237549 [Multi-domain] Cd Length: 606 Bit Score: 178.07 E-value: 3.07e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 1 MKKFNKQQSVFIFGIMLAFT-----WFSGsfAFFVLYFNQVQ---------NIKPLK-AIFKAIDAYNMDSFiKSLVLTG 65
Cdd:PRK13897 3 HKILNHIRNILGHAIIHFVVlefcfYISG--AFFALFTWGPGaldfnainpSIADFPwAYWPTIFNYIINVW-GQPKIYD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 66 VADEIRLIAFLALCSGFVLSLAIPVMALIK---LNEEKENVFGDARFATIKDVKESNSFTldgdeKEGIIVGlKDKKIIr 142
Cdd:PRK13897 80 YNLKLKLLASLLGPAIIVIIFYIKLRERIKswrPFKKKEKVHGDARWASESDIRKAGLRS-----KKGMLLG-KDKGGY- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 143 YVGAAF--SAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIRRVIlRQEVFKFDPFS--SVTHRFNPLFY 218
Cdd:PRK13897 153 FVADGFqhALLFAPTGSGKGVGFVIPNLLFWEDSVVVHDIKLENYELTSGWREKQ-GQKVFVWEPANpdGISHCYNPLDW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 219 VSMGTSEGFNQLENLALIVYPYKtdgadagSYLNKTAGSLFksLAVTLWFMiakdkqalkeldieplfsmskinllferA 298
Cdd:PRK13897 232 VSTKPGQMVDDVQKIANLIMPEQ-------DFWNNEARSLF--LGVVLYLL----------------------------A 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 299 DPENLLSF---LSEIRGD---------LKGKEKTLVDIGVSGLKAFIEMEDKTKAQLKSNFLNGLSPFSNPNVAKATDGN 366
Cdd:PRK13897 275 DPEKVKSFgevVRTMRSDdvvynlavvLDTLGKVIHPVAYMNIAAFLQKADKERSGVISTMNSSLELWANPLIDTATASS 354
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 367 DFDLRQVRKKRMTVYFCISGDNARLAEKVTNIFFQLAIQVNLEKMPTDDPeiKHDCLFLLDEFPSIGAVDYIKSKSGLIA 446
Cdd:PRK13897 355 DFNIQEFKKKKTTVYVGLTPDNLTRLQPLMQVFYQQATEFLCRKLPDKDE--PYGVLFLMDEFPTLGKMEQFKTGIAYFR 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 447 GYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTKTVTIGSKSKSR--SRGGMSRSESE 524
Cdd:PRK13897 433 GYRVRLFLIIQDTEQLKGIYEEAGMNSFLSNSTYRITFAANNIETANLISQLVGNKTVEQESLNKPKflDLNPASRSLHI 512
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2304598917 525 SLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYMNEYFFGDFIK--VAPSLESVFPKKN 587
Cdd:PRK13897 513 SEVQRALLLPQEVIMLPRDEQILLIESTYPIKSKKIKYYEDKFFTSRLLPptFVPTQEPYDPRAN 577
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
382-483 |
2.43e-10 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 58.77 E-value: 2.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 382 FCISGDNARLAEKVTNIFFQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQ 461
Cdd:cd01127 40 FLVIPDRDDSFAALRALFFNQLFRALTELASLSPGRLPRRVWFILDEFANLGRIPNLPNLLATGRKRGISVVLILQSLAQ 119
|
90 100
....*....|....*....|..
gi 2304598917 462 LEEIYSYAGSKTLLASAPCKIV 483
Cdd:cd01127 120 LEAVYGKDGAQTILGNCNTKLY 141
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| T4SS-DNA_transf |
pfam02534 |
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and ... |
120-568 |
1.13e-90 |
|
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.
Pssm-ID: 367119 [Multi-domain] Cd Length: 468 Bit Score: 288.53 E-value: 1.13e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 120 SFTLDGD-------EKEGIIVGLKDKKIIRYVGA----------AFSAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKR 182
Cdd:pfam02534 1 RWANDGDlesagllTRENTIIGDVYTKDPDAWYAggllntdgdfSHVLVFAGTGSGKGVGVVIPNLLVWKGSIVVLDPKG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 183 ECFNITSLIRRVILRqEVFKFDPFSSVTH-RFNPLFYVSMGTSEGFNQLENLALIVYPYKTDGADAGsyLNKTAGSLFKS 261
Cdd:pfam02534 81 ELWELTSGIREKQGR-KVFVLEPFNPKTSdRYNPLDYIDRGSEQETEDILKVASLIMPGKGGGRDDF--FNNTARQLLVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 262 LavtlWFMIAKDKQALKELDIEPLfsmskinLLFERADPENLLSFLSEIRGD-LKGKEKTLVdigVSGLKAFIEMEDKTK 340
Cdd:pfam02534 158 L----IALVLRSKPTRTIGQTLRF-------VRNMLSEPNLIENKELAVLLNeLDGSHHDRV---GDNLRFYVNKTDETR 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 341 AQLKSNFLNGLSPFSNPNVAKATDGNDFDLRQVRKKRMTVYFCISGDNARLAEKVTNIFFQLAIQVNLEKMPTDDPEIKH 420
Cdd:pfam02534 224 SSVIGTAVSELALYADPEVRNATSGSDFDLRDLRRDKTSVYVILNPKDLTVVSPLLRVFFQMVVELLYLKLPNGDGRPKE 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 421 dCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSAS-DVKDARELSEAM 499
Cdd:pfam02534 304 -VLFLLDEFPSLGKLEILEEALATIRGYGIRLTTICQSISQLKETYGGEGAKSILSNHAVVICFAASnDEETAKYISKLL 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2304598917 500 GTKTVTIGSKSKSRSRGGMSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYMNEYF 568
Cdd:pfam02534 383 GKTTVEVESSSKSTDAKGSSRSRSISEVQRPLLTPDEVLRMPDDEQIVITKGQPPIKCKKALYFKDEDF 451
|
|
| VirD4 |
COG3505 |
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ... |
153-563 |
6.61e-79 |
|
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain] Cd Length: 402 Bit Score: 255.29 E-value: 6.61e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 153 AGTRAGKGAGIVITNLMKYW--WSVIILDPKRECFNITSLIRRvILRQEVFKFDPFSSV-THRFNPLFYVsmgtsEGFNQ 229
Cdd:COG3505 6 GPTGSGKTVGLVIPNLTQLArgESVVVTDPKGDLAELTAGFRR-RAGYDVYVFDPFDPErSHRWNPLDEI-----RDPAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 230 LENLALIVYPYKTDGADAGSYLNKTAGSLFKSLavtLWFMIAKDKQALKELdieplfsmskinllferadPENLLSFLSE 309
Cdd:COG3505 80 AQELAEALIPALGGGGGGDPFWREAARALLAAL---ILALAEEGRRTLADV-------------------YRLLSEPEEE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 310 IRGDLKGKEKTLVDIGVSGLKAFIEMEDKTKAQLKSNFLNGLSPFSNPNVAKATDGNDFDLRQVRKKRMTVYFCISGDNA 389
Cdd:COG3505 138 LRELLEALPESPHPPVADTLAAFLNAAEKTRSSVLSTLASALELLSDPEVAALTSGSDFDLRDLIREKGTLYLVLPPDDL 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 390 RLAEKVTNIFFQLAIQVNLEKMPTDDPEiKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYA 469
Cdd:COG3505 218 STLAPLLRLLLSQLIRALLRRAERSGRL-PRPVLLLLDEFANLGRLPSLETLLATGRGYGIRLVLILQSLAQLEAIYGEE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 470 GSKTLLASAPCKIVYSASDVKDARELSEAMGTKTVTigSKSKSRSRGgmSRSESESLIERPLVTTNELLTLKFSEEILAM 549
Cdd:COG3505 297 GAETILGNCGTKIFLGVNDPETAEYLSELLGKRTVE--RRSESRSRG--SRSRSRSEQERPLLTPDELRRLPDGEAIVLV 372
|
410
....*....|....
gi 2304598917 550 KGENPIRCEKAFYY 563
Cdd:COG3505 373 RGGPPIRAKKIRYY 386
|
|
| PRK13897 |
PRK13897 |
type IV secretion system component VirD4; Provisional |
1-587 |
3.07e-48 |
|
type IV secretion system component VirD4; Provisional
Pssm-ID: 237549 [Multi-domain] Cd Length: 606 Bit Score: 178.07 E-value: 3.07e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 1 MKKFNKQQSVFIFGIMLAFT-----WFSGsfAFFVLYFNQVQ---------NIKPLK-AIFKAIDAYNMDSFiKSLVLTG 65
Cdd:PRK13897 3 HKILNHIRNILGHAIIHFVVlefcfYISG--AFFALFTWGPGaldfnainpSIADFPwAYWPTIFNYIINVW-GQPKIYD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 66 VADEIRLIAFLALCSGFVLSLAIPVMALIK---LNEEKENVFGDARFATIKDVKESNSFTldgdeKEGIIVGlKDKKIIr 142
Cdd:PRK13897 80 YNLKLKLLASLLGPAIIVIIFYIKLRERIKswrPFKKKEKVHGDARWASESDIRKAGLRS-----KKGMLLG-KDKGGY- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 143 YVGAAF--SAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIRRVIlRQEVFKFDPFS--SVTHRFNPLFY 218
Cdd:PRK13897 153 FVADGFqhALLFAPTGSGKGVGFVIPNLLFWEDSVVVHDIKLENYELTSGWREKQ-GQKVFVWEPANpdGISHCYNPLDW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 219 VSMGTSEGFNQLENLALIVYPYKtdgadagSYLNKTAGSLFksLAVTLWFMiakdkqalkeldieplfsmskinllferA 298
Cdd:PRK13897 232 VSTKPGQMVDDVQKIANLIMPEQ-------DFWNNEARSLF--LGVVLYLL----------------------------A 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 299 DPENLLSF---LSEIRGD---------LKGKEKTLVDIGVSGLKAFIEMEDKTKAQLKSNFLNGLSPFSNPNVAKATDGN 366
Cdd:PRK13897 275 DPEKVKSFgevVRTMRSDdvvynlavvLDTLGKVIHPVAYMNIAAFLQKADKERSGVISTMNSSLELWANPLIDTATASS 354
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 367 DFDLRQVRKKRMTVYFCISGDNARLAEKVTNIFFQLAIQVNLEKMPTDDPeiKHDCLFLLDEFPSIGAVDYIKSKSGLIA 446
Cdd:PRK13897 355 DFNIQEFKKKKTTVYVGLTPDNLTRLQPLMQVFYQQATEFLCRKLPDKDE--PYGVLFLMDEFPTLGKMEQFKTGIAYFR 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 447 GYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTKTVTIGSKSKSR--SRGGMSRSESE 524
Cdd:PRK13897 433 GYRVRLFLIIQDTEQLKGIYEEAGMNSFLSNSTYRITFAANNIETANLISQLVGNKTVEQESLNKPKflDLNPASRSLHI 512
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2304598917 525 SLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYMNEYFFGDFIK--VAPSLESVFPKKN 587
Cdd:PRK13897 513 SEVQRALLLPQEVIMLPRDEQILLIESTYPIKSKKIKYYEDKFFTSRLLPptFVPTQEPYDPRAN 577
|
|
| PRK13850 |
PRK13850 |
type IV secretion system protein VirD4; Provisional |
149-594 |
2.85e-35 |
|
type IV secretion system protein VirD4; Provisional
Pssm-ID: 237531 [Multi-domain] Cd Length: 670 Bit Score: 141.55 E-value: 2.85e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 149 SAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIRRViLRQEVFKFDPFSSV--THRFNPLFYVS-MGTSE 225
Cdd:PRK13850 142 SLVVAPTRAGKGVGVVIPTLLTFKGSVIALDVKGELFELTSRARKA-SGDAVFKFAPLDPErrTHCYNPVLDIAaLPPER 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 226 GFNQLENLALIVYPYKTDGADAgsYLNKtAGSLFKSLAVTLwfmiakdkqalkeldIE---PlfSMSKINLLFerADPEN 302
Cdd:PRK13850 221 RFTETRRLAANLITAKGKGAEG--FIDG-ARDLFVAGILAC---------------IErgtP--TIGAVYDLF--AQPGE 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 303 LLSFLSEIRGDLKGKEktlvdigvsGLKAFIEMEDkTKAQLKSNFLN-----GLSPFSNPNVAKATDGNDFDLRQVRKKR 377
Cdd:PRK13850 279 KYKLFAQLAEETQNKE---------AQRIFDNMAG-NDTKILTSYTSvlgdgGLNLWADPLVKAATSRSDFSVYDLRRKR 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 378 MTVYFCISGDNARLAEKVTNIFFQLAIQVNLEKMPTDDPeiKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQ 457
Cdd:PRK13850 349 TCIYLCVSPNDLEVVAPLMRLLFQQVVSILQRSLPGKDE--RHEVLFLLDEFKHLGKLEAIETAITTIAGYKGRFMFIIQ 426
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 458 VGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTKTVTIGSKSKSRSRgGMSRSESESLIERPLVTTNEL 537
Cdd:PRK13850 427 SLSALTGTYDEAGKQNFLSNTGVQVFMATADDETPTYISKAIGDYTFKARSTSYSQAR-MFDHNIQISDQGAPLLRPEQV 505
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 2304598917 538 LTLKFSEEILAMKGENPIRCEKAFYYMNEyffgdfikvapSLESVFPKKNGKLSMPP 594
Cdd:PRK13850 506 RLLDDDTEIVLIKGQPPLKLRKVRYYSDR-----------ELKRIFEAQTGSLPEPA 551
|
|
| PRK13880 |
PRK13880 |
conjugal transfer coupling protein TraG; Provisional |
73-540 |
1.99e-28 |
|
conjugal transfer coupling protein TraG; Provisional
Pssm-ID: 237540 Cd Length: 636 Bit Score: 120.62 E-value: 1.99e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 73 IAFLALCSGFVLSLAIPVMALIKLNEEKENVFGDARFATIKDVKES-----------NSFTLDGDEKEGIIVG-LKDKK- 139
Cdd:PRK13880 86 SIGMVVSTVGLLGVAVAKVVTSNSSKANEYLHGSARWAEKKDIQAAgllprernvleIVTGKAAPTATGVYVGgWQDKDg 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 140 ---IIRYVGAAFSAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIRRVILRQEVFKFDPFSSV-THRFNP 215
Cdd:PRK13880 166 nfhYLRHNGPEHVLTYAPTRSGKGVGLVVPTLLSWGHSSVITDLKGELWALTAGWRQKHAKNKVLRFEPASLSgSVCWNP 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 216 LFYVSMGTSEGFNQLENLA-LIVYPyktDGADAGSYLNKTAGSLFKSLAVtlwfmiakdkQALKELDIEPLF-SMSKINL 293
Cdd:PRK13880 246 LDEIRLGTEYEVGDVQNLAtLIVDP---DGKGLESHWQKTAFALLVGVIL----------HALYKAKNEGGTaTLPSVDA 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 294 LFerADPE-NLLSFLSEIR--GDLKGKEKTLvdIGVSGlKAFIEMEDKTKAQLKSNFLNGLSPFSNPNVAKATDGNDFDL 370
Cdd:PRK13880 313 ML--ADPNrDIGELWMEMTtyGHVDGQNHPA--IGSAA-RDMMDRPEEEAGSVLSTAKSYLALYRDPVVARNVSRSDFRI 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 371 RQVRKKRMTVYFCI---SGDNARLAEKVtNIFFQLAIQVNLEKMPTDD----PEIKHDCLFLLDEFPSIGAVDYIKSKSG 443
Cdd:PRK13880 388 KDLMHHDDPVSLYIvtqPNDKARLRPLV-RVMVNMIVRLLADKMDFENgrpvAHYKHRLLMMLDEFPSLGKLEILQESLA 466
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 444 LIAGYKLKLLIVYQVGSQLEEIYS-YAGSKTLLASAPCKIVYSASDVKDARELSEAMGTKTV-----TIGSKSKSRSRGG 517
Cdd:PRK13880 467 FVAGYGIKCYLICQDINQLKSRETgYGHDESITSNCHVQNAYPPNRVETAEHLSKLTGQTTVvkeqiTTSGRRTSAMLGQ 546
|
490 500
....*....|....*....|...
gi 2304598917 518 MSRSESEslIERPLVTTNELLTL 540
Cdd:PRK13880 547 VSRTYQE--VQRPLLTPDECLRM 567
|
|
| TraG-D_C |
pfam12696 |
TraM recognition site of TraD and TraG; This family includes both TraG and TraD as well as ... |
422-542 |
1.43e-26 |
|
TraM recognition site of TraD and TraG; This family includes both TraG and TraD as well as VirD4 proteins. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. This domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore.
Pssm-ID: 432726 [Multi-domain] Cd Length: 125 Bit Score: 104.65 E-value: 1.43e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 422 CLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGT 501
Cdd:pfam12696 2 VLFVLDEFANLGKIPDLEKLISTGRSRGISLMLILQSIAQLEELYGKDGAETILGNCNTKVFLGGGDEETAKYLSKLLGK 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2304598917 502 KTVTIGSKSKSRSRGG---MSRSESESLIERPLVTTNELLTLKF 542
Cdd:pfam12696 82 YTVVSTTTSSSSSGSGgsgSSSSSSSQLVGRPLLTPDELRRLPR 125
|
|
| PRK13822 |
PRK13822 |
conjugal transfer coupling protein TraG; Provisional |
73-563 |
8.17e-21 |
|
conjugal transfer coupling protein TraG; Provisional
Pssm-ID: 237522 [Multi-domain] Cd Length: 641 Bit Score: 96.57 E-value: 8.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 73 IAFLALCsgFVLSLAIPVMALIKLNEE-----KENVFGDARFATIKDVkeSNSFTLDGdekeGIIVGLK---DKKIIRYV 144
Cdd:PRK13822 126 VGFFAGA--FALRVSLVGNAAFARAEPrrirgKRAIHGDADWMKMKEA--AKLFPPDG----GIVIGERyrvDKDSVAAL 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 145 gaAFSAM-----GAGTR------------------AGKGA----GIVITNLMKYWWSVIILDPKRECFNITSLIRRVILR 197
Cdd:PRK13822 198 --PFRPDdrttwGKGGKaplltfdgdfgsthglvfAGSGGfkttSVVVPTALKWGGPLVVLDPSTEVAPMVSEHRRDAGR 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 198 qEVFKFDPFSSVTHrFNPLFYV--SMGTSEgfnqlENLALIVYPYKTDGADAGSylnkTAGSLFKSLAVTLWF-MIA--- 271
Cdd:PRK13822 276 -EVIVLDPTNPGTG-FNVLDWIgrSGGTKE-----EDIVAVASWILSDSKRTES----SRDDFFRNSAHQLLTaLLAhvc 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 272 ------KDKQALKELdieplfsmsKINLlferADPENllSFLSEIRGDLKGKEKTLVDIGVSglkAFIEMEDKTKAQLKS 345
Cdd:PRK13822 345 lsgeyeGKERTLRTL---------RAIL----SEPEP--SLRARLRDIYENSESDFIRENVG---VFVNMTEQTFSGVYA 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 346 NFLNGLSPFSNPNVAKATDGNDFDLRQVRKKRMTVYFCISG----DNARLAEKVTNIFfqlaiqvnLEKMPTDDPEIKHD 421
Cdd:PRK13822 407 TASKDTQWLSYPNYAALVSGNSFSTSDLAAGNTDVFINIPLkileSYPGLARVIIGSL--------LNAMYNADGNVKGR 478
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 422 CLFLLDEFPSIG-------AVDyiksksgliAG--YKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCkIVYSA-SDVKD 491
Cdd:PRK13822 479 ALFLLDEVARLGymriletARD---------AGrkYGITLMLIYQSIGQLREHFGGRGATSWFESASW-ISFAAiKDLDT 548
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2304598917 492 ARELSEAMGTKTVTIGSKSKSRSRGGMSRSESESLIERPLVTTNELL-TLKFSEEILAMKGENPIRCEKAFYY 563
Cdd:PRK13822 549 ADYISERCGEMTVEVDQTSRSSGWSGSSRSRSKQLQRRPLIMPHEILqSMRADEQIIFVQGNPPLRCGRAIYF 621
|
|
| PRK13876 |
PRK13876 |
conjugal transfer coupling protein TraG; Provisional |
8-563 |
1.74e-19 |
|
conjugal transfer coupling protein TraG; Provisional
Pssm-ID: 237538 Cd Length: 663 Bit Score: 92.68 E-value: 1.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 8 QSVFIFGIMLAFTWFSGSFAFFVLYFnQVQNIKPLKAIFK--------------AIDAYNMDSFIKSlvltgvadeirli 73
Cdd:PRK13876 10 QIAVVFLIVLAGVWAATQWTAWALGF-QPQLGSPWFDLFGwpvyyppaffwwwyFFDAYAPHVFDEG------------- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 74 AFLALCSGFV-LSLAIpVMALIKLNEEKeNV--FGDARFATIKDVKESNsftLDGDEkeGIIVGLKDKKIIRYVGA---- 146
Cdd:PRK13876 76 GAIAASGGFVaIAVAI-AMSVWRAREAK-RVttYGSARWAERREIRAAG---LLGPD--GVVLGRHDRDYLRHDGPehvl 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 147 AFsamgAGTRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIR----RVILrqevfkFDPFSSVTHRFNPLFYVSMG 222
Cdd:PRK13876 149 CF----APTRSGKGVGLVVPTLLTWPGSAIVHDIKGENWQLTAGFRarfgRVLL------FDPTNAKSAAYNPLLEVRRG 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 223 TSEgFNQLENLALI-VYPyktDGA-DAGSYLNKTAGSLF-------------KSLA--------------VTLWFMIAKd 273
Cdd:PRK13876 219 EWE-VRDVQNIADIlVDP---EGSlERRNHWEKTSHALLvgailhvlyaeedKTLAgvanflsdpkrpieATLRAMMTT- 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 274 kQALKELDIEPLFSMSKINLLfERADPE------NLLSFLseirgdlkgkektlvdigvsglkafiemedktkaqlksnf 347
Cdd:PRK13876 294 -PHLGEAGPHPVVASAARELL-NKSDNErsgvlsTAMSFL---------------------------------------- 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 348 lnGLspFSNPNVAKATDGNDF---DLrqVRKKR-MTVYFCIS-GDNARLAEKVTNIFFQLAIQVNlEKMPTDDPeiKHDC 422
Cdd:PRK13876 332 --GL--YRDPVVAEVTSRCDWriaDL--VAGERpVSLYLVVPpSDISRTKPLIRLILNQIGRRLT-EDLDGKAR--RHRL 402
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 423 LFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSktLLASAPCKIVYSASDVKDARELSEAMGTK 502
Cdd:PRK13876 403 LLMLDEFPALGRLDFFESALAFMAGYGIKSFLIAQSLNQIEKAYGQNNS--ILDNCHVRVSFATNDERTAKRVSDALGTA 480
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2304598917 503 TVTIGSKSKSRSR-----GGMSRSESESliERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYY 563
Cdd:PRK13876 481 TELRAMKNYAGHRlspwlGHLMVSRQET--ARPLLTPGEVMQLPPDDEIVMVSGVPPIRAKKARYY 544
|
|
| TrwB_AAD_bind |
pfam10412 |
Type IV secretion-system coupling protein DNA-binding domain; The plasmid conjugative coupling ... |
362-540 |
9.51e-13 |
|
Type IV secretion-system coupling protein DNA-binding domain; The plasmid conjugative coupling protein TrwB forms hexamers from six structurally very similar protomers. This hexamer contains a central channel running from the cytosolic pole (made up by the AADs) to the membrane pole ending at the transmembrane pore shaped by 12 transmembrane helices, rendering an overall mushroom-like structure. The TrwB_AAD (all-alpha domain) domain appears to be the DNA-binding domain of the structure. TrwB, a basic integral inner-membrane nucleoside-triphosphate-binding protein, is the structural prototype for the type IV secretion system coupling proteins, a family of proteins essential for macromolecular transport between cells and export.
Pssm-ID: 431268 [Multi-domain] Cd Length: 386 Bit Score: 70.02 E-value: 9.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 362 ATDGNDFDLRQ-VRKKRMTVYFCISGDNARLAekVTNIFFQ----LAIQVNLEKMPTDDPEIkhdcLFLLDEFPSIGAVD 436
Cdd:pfam10412 186 APDGERFSIREwITEEDPGGWLFITYRADQRA--ALRPLLScwldLAIRALLSLPPSRDRRL----WFFLDELPALGRLP 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 437 YIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMG-------TKTVTIGsk 509
Cdd:pfam10412 260 SLKDLLAEGRKFGGAVVLGLQSIAQLREIYGEDGAQTILSNCGTKLILRVSDGETAELCSDLLGdrevermDESLSYG-- 337
|
170 180 190
....*....|....*....|....*....|.
gi 2304598917 510 sKSRSRGGMSRSESESliERPLVTTNELLTL 540
Cdd:pfam10412 338 -ANNSRDGVTLGRQRR--VRPLVLPSEIMNL 365
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
382-483 |
2.43e-10 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 58.77 E-value: 2.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2304598917 382 FCISGDNARLAEKVTNIFFQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQ 461
Cdd:cd01127 40 FLVIPDRDDSFAALRALFFNQLFRALTELASLSPGRLPRRVWFILDEFANLGRIPNLPNLLATGRKRGISVVLILQSLAQ 119
|
90 100
....*....|....*....|..
gi 2304598917 462 LEEIYSYAGSKTLLASAPCKIV 483
Cdd:cd01127 120 LEAVYGKDGAQTILGNCNTKLY 141
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
153-185 |
1.11e-03 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 39.90 E-value: 1.11e-03
10 20 30
....*....|....*....|....*....|....*
gi 2304598917 153 AGTRAGKGAGIVITNLMKYW--WSVIILDPKRECF 185
Cdd:cd01127 6 GTTGSGKTTSIVIPLLDQAArgGSVIITDPKGELF 40
|
|
| |
