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Conserved domains on  [gi|2314553684|ref|WP_262861556|]
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choline BCCT transporter BetT [Morganella morganii]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
5-512 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 706.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684   5 DTEQSAKKMKINPPVFYISALVILLIVGFAALFPQTADIHLKALQTSLFKNASWFYILAVALILLSVTFMGLSRFGDIKL 84
Cdd:COG1292     3 DKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  85 GPDHARPAYSYISWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVEAAKEAMRLTFFHWGLHAWAIYAVVALIL 163
Cdd:COG1292    83 GGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLAL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 164 AFFSYRHGLPLTLRSALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFGVLQVNAGLNHLFGLPQTETVQVVLIVVI 243
Cdd:COG1292   163 AYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVI 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 244 TSLATLSVVSGLDKGIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTGGYLSEIVSNTFNLFAYEPksDDWLGGWT 323
Cdd:COG1292   243 TALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGGWT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 324 LLYWGWWLSWSPFVGMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNTAIDLIKNqGATALATVVKEDVSLALFQF 403
Cdd:COG1292   321 VFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEAALFAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 404 LEYFPFSTVLSFFAMLMVIVFFVTSADSGAMVVDTLASGGDAHTPVWQRIFWAGLMGVVAITLLLAGGLSALQTVTIASA 483
Cdd:COG1292   400 LEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITA 479
                         490       500
                  ....*....|....*....|....*....
gi 2314553684 484 LPFAVVLLFSIYGLIKALRIDVHKRDSQQ 512
Cdd:COG1292   480 LPFSFVLLLMCVSLVKALREDPRRLRSAE 508
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
5-512 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 706.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684   5 DTEQSAKKMKINPPVFYISALVILLIVGFAALFPQTADIHLKALQTSLFKNASWFYILAVALILLSVTFMGLSRFGDIKL 84
Cdd:COG1292     3 DKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  85 GPDHARPAYSYISWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVEAAKEAMRLTFFHWGLHAWAIYAVVALIL 163
Cdd:COG1292    83 GGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLAL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 164 AFFSYRHGLPLTLRSALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFGVLQVNAGLNHLFGLPQTETVQVVLIVVI 243
Cdd:COG1292   163 AYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVI 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 244 TSLATLSVVSGLDKGIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTGGYLSEIVSNTFNLFAYEPksDDWLGGWT 323
Cdd:COG1292   243 TALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGGWT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 324 LLYWGWWLSWSPFVGMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNTAIDLIKNqGATALATVVKEDVSLALFQF 403
Cdd:COG1292   321 VFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEAALFAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 404 LEYFPFSTVLSFFAMLMVIVFFVTSADSGAMVVDTLASGGDAHTPVWQRIFWAGLMGVVAITLLLAGGLSALQTVTIASA 483
Cdd:COG1292   400 LEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITA 479
                         490       500
                  ....*....|....*....|....*....
gi 2314553684 484 LPFAVVLLFSIYGLIKALRIDVHKRDSQQ 512
Cdd:COG1292   480 LPFSFVLLLMCVSLVKALREDPRRLRSAE 508
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-662 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 689.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684   1 MSHQDTEQSAKKMKINPPVFYISALVILLIVGFAALFPQTADIHLKALQTSLFKNASWFYILAVALILLSVTFMGLSRFG 80
Cdd:PRK09928    1 MVMTDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  81 DIKLGPDHARPAYSYISWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVEAAKEAMRLTFFHWGLHAWAIYAVVA 160
Cdd:PRK09928   81 SIKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 161 LILAFFSYRHGLPLTLRSALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFGVLQVNAGLNHLFGLPQTETVQVVLI 240
Cdd:PRK09928  161 MALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALI 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 241 VVITSLATLSVVSGLDKGIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTGGYLSEIVSNTFNLFAYEPKSdDWLG 320
Cdd:PRK09928  241 ALSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPT-EWMN 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 321 GWTLLYWGWWLSWSPFVGMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNTAIDLIKNqGATALATVVKEDVSLAL 400
Cdd:PRK09928  320 NWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGF 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 401 FQFLEYFPFSTVLSFFAMLMVIVFFVTSADSGAMVVDTLAS-----GGDAhtPVWQRIFWAGLMGVVAITLLLAGGLSAL 475
Cdd:PRK09928  399 YSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSklkdiNSDA--PNWLRVFWSVAIGLLTLGMLMTNGISAL 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 476 QTVTIASALPFAVVLLFSIYGLIKALRIDVHKRDSQQLATiAPTAS--RNPIPWQRRLRNIGYFPKRSLVKRFIDEVVSE 553
Cdd:PRK09928  477 QNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDT-APRLVglQDRLNWKQRLSRVMNYPGTRYTRRMLDTVCRP 555
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 554 AMEMVSQELEKQSTPSRI------DRSRDDRITFEVDLGDDMNFIYETRLRYYNQPSFALSGmtdeeKDEEHRYYRAEIH 627
Cdd:PRK09928  556 AMEEVAQELRLRGAYVELnelppeEDERLGHLDLLVHLGDEQNFVYQIWPQRYSVPGFTYRA-----RSGKSTYYRLETF 630
                         650       660       670
                  ....*....|....*....|....*....|....*
gi 2314553684 628 LKEGGQDYDIMGWNKEQIIHDILDQYEKHIHFLHL 662
Cdd:PRK09928  631 LLEGSQGNDLMDYSKEQVINDILDQYERHLNFLHL 665
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
19-504 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 637.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  19 VFYISALVILLIVGFAALFPQTADIHLKALQTSLFKNASWFYILAVALILLSVTFMGLSRFGDIKLGPDHARPAYSYISW 98
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  99 FAMLFSAGMGIGLMFFGVAEPVMHYLS-PPVGTPETVEAAKEAMRLTFFHWGLHAWAIYAVVALILAFFSYRHGLPLTLR 177
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 178 SALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFGVLQVNAGLNHLFGLPQTETVQVVLIVVITSLATLSVVSGLDK 257
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 258 GIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTGGYLSEIVSNTFNLFAYEPkSDDWLGGWTLLYWGWWLSWSPFV 337
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGD-TGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 338 GMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNTAIDLIKNqGATALATVVKEDVSLALFQFLEYFPFSTVLSFFA 417
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELN-GPGDLADAVEAGPPAALFALLEQLPLGTILSVLA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 418 MLMVIVFFVTSADSGAMVVDTLASGGDAHTPVWQRIFWAGLMGVVAITLLLAGGLSALQTVTIASALPFAVVLLFSIYGL 497
Cdd:pfam02028 399 LLLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISL 478

                  ....*..
gi 2314553684 498 IKALRID 504
Cdd:pfam02028 479 FKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
57-504 1.10e-167

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 487.63  E-value: 1.10e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  57 SWFYILAVALILLSVTFMGLSRFGDIKLGPDHARPAYSYISWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVEA 136
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 137 AKE-AMRLTFFHWGLHAWAIYAVVALILAFFSYRHGLPLTLRSALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFG 215
Cdd:TIGR00842  81 AQEqALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 216 VLQVNAGLNHLFGLPQTETVQVVLIVVITSLATLSVVSGLDKGIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTG 295
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 296 GYLSEIVSNTFNLFAyEPKSDDWLGGWTLLYWGWWLSWSPFVGMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNT 375
Cdd:TIGR00842 241 NYLQNFPQMSFRTDP-DDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 376 AIDLIKNQGATALATVVKEDVSLALFQFLEYFPFSTVLSFFAMLMVIVFFVTSADSGAMVVDTLASGG---DAHTPVWQR 452
Cdd:TIGR00842 320 ALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlGEEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2314553684 453 IFWAGLMGVVAITLLLA-GGLSALQTVTIASALPFAVVLLFSIYGLIKALRID 504
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSgGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
5-512 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 706.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684   5 DTEQSAKKMKINPPVFYISALVILLIVGFAALFPQTADIHLKALQTSLFKNASWFYILAVALILLSVTFMGLSRFGDIKL 84
Cdd:COG1292     3 DKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  85 GPDHARPAYSYISWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVEAAKEAMRLTFFHWGLHAWAIYAVVALIL 163
Cdd:COG1292    83 GGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLAL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 164 AFFSYRHGLPLTLRSALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFGVLQVNAGLNHLFGLPQTETVQVVLIVVI 243
Cdd:COG1292   163 AYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVI 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 244 TSLATLSVVSGLDKGIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTGGYLSEIVSNTFNLFAYEPksDDWLGGWT 323
Cdd:COG1292   243 TALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGGWT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 324 LLYWGWWLSWSPFVGMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNTAIDLIKNqGATALATVVKEDVSLALFQF 403
Cdd:COG1292   321 VFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEAALFAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 404 LEYFPFSTVLSFFAMLMVIVFFVTSADSGAMVVDTLASGGDAHTPVWQRIFWAGLMGVVAITLLLAGGLSALQTVTIASA 483
Cdd:COG1292   400 LEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITA 479
                         490       500
                  ....*....|....*....|....*....
gi 2314553684 484 LPFAVVLLFSIYGLIKALRIDVHKRDSQQ 512
Cdd:COG1292   480 LPFSFVLLLMCVSLVKALREDPRRLRSAE 508
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-662 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 689.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684   1 MSHQDTEQSAKKMKINPPVFYISALVILLIVGFAALFPQTADIHLKALQTSLFKNASWFYILAVALILLSVTFMGLSRFG 80
Cdd:PRK09928    1 MVMTDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  81 DIKLGPDHARPAYSYISWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVEAAKEAMRLTFFHWGLHAWAIYAVVA 160
Cdd:PRK09928   81 SIKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 161 LILAFFSYRHGLPLTLRSALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFGVLQVNAGLNHLFGLPQTETVQVVLI 240
Cdd:PRK09928  161 MALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALI 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 241 VVITSLATLSVVSGLDKGIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTGGYLSEIVSNTFNLFAYEPKSdDWLG 320
Cdd:PRK09928  241 ALSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPT-EWMN 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 321 GWTLLYWGWWLSWSPFVGMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNTAIDLIKNqGATALATVVKEDVSLAL 400
Cdd:PRK09928  320 NWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGF 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 401 FQFLEYFPFSTVLSFFAMLMVIVFFVTSADSGAMVVDTLAS-----GGDAhtPVWQRIFWAGLMGVVAITLLLAGGLSAL 475
Cdd:PRK09928  399 YSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSklkdiNSDA--PNWLRVFWSVAIGLLTLGMLMTNGISAL 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 476 QTVTIASALPFAVVLLFSIYGLIKALRIDVHKRDSQQLATiAPTAS--RNPIPWQRRLRNIGYFPKRSLVKRFIDEVVSE 553
Cdd:PRK09928  477 QNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDT-APRLVglQDRLNWKQRLSRVMNYPGTRYTRRMLDTVCRP 555
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 554 AMEMVSQELEKQSTPSRI------DRSRDDRITFEVDLGDDMNFIYETRLRYYNQPSFALSGmtdeeKDEEHRYYRAEIH 627
Cdd:PRK09928  556 AMEEVAQELRLRGAYVELnelppeEDERLGHLDLLVHLGDEQNFVYQIWPQRYSVPGFTYRA-----RSGKSTYYRLETF 630
                         650       660       670
                  ....*....|....*....|....*....|....*
gi 2314553684 628 LKEGGQDYDIMGWNKEQIIHDILDQYEKHIHFLHL 662
Cdd:PRK09928  631 LLEGSQGNDLMDYSKEQVINDILDQYERHLNFLHL 665
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
19-504 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 637.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  19 VFYISALVILLIVGFAALFPQTADIHLKALQTSLFKNASWFYILAVALILLSVTFMGLSRFGDIKLGPDHARPAYSYISW 98
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  99 FAMLFSAGMGIGLMFFGVAEPVMHYLS-PPVGTPETVEAAKEAMRLTFFHWGLHAWAIYAVVALILAFFSYRHGLPLTLR 177
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 178 SALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFGVLQVNAGLNHLFGLPQTETVQVVLIVVITSLATLSVVSGLDK 257
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 258 GIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTGGYLSEIVSNTFNLFAYEPkSDDWLGGWTLLYWGWWLSWSPFV 337
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGD-TGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 338 GMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNTAIDLIKNqGATALATVVKEDVSLALFQFLEYFPFSTVLSFFA 417
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELN-GPGDLADAVEAGPPAALFALLEQLPLGTILSVLA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 418 MLMVIVFFVTSADSGAMVVDTLASGGDAHTPVWQRIFWAGLMGVVAITLLLAGGLSALQTVTIASALPFAVVLLFSIYGL 497
Cdd:pfam02028 399 LLLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISL 478

                  ....*..
gi 2314553684 498 IKALRID 504
Cdd:pfam02028 479 FKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
57-504 1.10e-167

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 487.63  E-value: 1.10e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  57 SWFYILAVALILLSVTFMGLSRFGDIKLGPDHARPAYSYISWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVEA 136
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 137 AKE-AMRLTFFHWGLHAWAIYAVVALILAFFSYRHGLPLTLRSALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFG 215
Cdd:TIGR00842  81 AQEqALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 216 VLQVNAGLNHLFGLPQTETVQVVLIVVITSLATLSVVSGLDKGIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTG 295
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 296 GYLSEIVSNTFNLFAyEPKSDDWLGGWTLLYWGWWLSWSPFVGMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNT 375
Cdd:TIGR00842 241 NYLQNFPQMSFRTDP-DDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 376 AIDLIKNQGATALATVVKEDVSLALFQFLEYFPFSTVLSFFAMLMVIVFFVTSADSGAMVVDTLASGG---DAHTPVWQR 452
Cdd:TIGR00842 320 ALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlGEEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2314553684 453 IFWAGLMGVVAITLLLA-GGLSALQTVTIASALPFAVVLLFSIYGLIKALRID 504
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSgGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09950 PRK09950
putative transporter; Provisional
11-504 9.37e-65

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 222.36  E-value: 9.37e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  11 KKMKINPPVFYISALVILLIVGFAALFPQTADIHLKALQTSLFKNASWFYILAVALILLSVTFMGLSRFGDIKLGpdHAR 90
Cdd:PRK09950    4 NKKKKDKPLISTSLLAVFFIVAALSLFPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLG--EGK 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  91 PAYSYISWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVEAAKEAMRLTFFHWGLHAWAIYAVVALILAF-FSY 168
Cdd:PRK09950   82 PEYSTLSWLFMFICAGLGSSTLYWGVMEWAYYYQTPGLNiAPRSPKALEYSVSYSFFHWGISAWATYALASLIMAYhFHV 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 169 RHGLPLTLRSALYPIIGDRIYGAAGHAVDIFAVVGTVFGVATSLGFGVLQVNAGLNHLFGLPQTETVQVVLIVVITSLAT 248
Cdd:PRK09950  162 RKNKGLSLSGIIAAITGVKPQGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIFC 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 249 LSVVSGLDKGIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTGGYLSEIVSntFNLFAYEPKSDDWLGGWTLLYWG 328
Cdd:PRK09950  242 LSSYIGIDNGLQRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFLQ--MSLFTDPMGDGSFTRNWTVFYWL 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 329 WWLSWSPFVGMFIARISRGRTIREFVFGVLfvpAGFTLLWMTFFG---NTAIDLIKNQGATALATVVKEDVSLALFQFLE 405
Cdd:PRK09950  320 WWISYTPGVAMFVTRVSRGRKIKEVIWGLI---LGSSVGCWFFFGvleSYAIHQFINGVINVPQILNTLGGETAVQQLLS 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 406 YFPFSTVLSFFAMLMVIVFFVTSADSGAMVVDTLA----SGGDAHTPVwQRIFWAGLMGVVAITLLLAGGLS-ALQTVTI 480
Cdd:PRK09950  397 SLPAGKLFLAAYLGIMIIFLASHMDAVAYTMAATStrnlREGDDPDRG-LRLFWCVVITLIPLSILFTGASLdTMKTTVV 475
                         490       500
                  ....*....|....*....|....
gi 2314553684 481 ASALPFAVVLLFSIYGLIKALRID 504
Cdd:PRK09950  476 LTALPFLVILLIKVYGFIRWLKQD 499
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
6-502 3.96e-61

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 212.29  E-value: 3.96e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684   6 TEQSAKKMKINPPVFYISALVILLIVGFAALFPQTADIHLKALQTSLFKNASWFYILAVALILLSVTFMGLSRFGDIKLG 85
Cdd:PRK03356    1 MKNEKKKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684  86 PDhaRPAYSYISWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVEAAKEAMRLTFFHWGLHAWAIYAVVALILA 164
Cdd:PRK03356   81 DE--KPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGlEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 165 FFSYRHGLPLTLRS-ALYPIIGDR-IYGAAGHAVDIFAVVGTVFGVATSLGFGVLQVNAGLNHLFGLPQTETVQVVLIVV 242
Cdd:PRK03356  159 YFFFVRKMDVIRPSsTLVPLVGEKhAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITC 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 243 ITSLATLSVVSGLDKGIRFLSELNLGLAVLLLIMVGVLGPTVLLLKSFVENTGGYLSEIVSNTFNLFAYEPKSddWLGGW 322
Cdd:PRK03356  239 WIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPIGKGG--FPQGW 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 323 TLLYWGWWLSWSPFVGMFIARISRGRTIREFVFGVLFVPAGFTLLWMTFFGNTAIDLIKNQGATALATVVKEDVSLALFQ 402
Cdd:PRK03356  317 TVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLMDKNIINIPNLIEQYGVARAIIE 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314553684 403 FLEYFPFSTVLSFFAMLMVIVFFVTSADSG----AMVVDTLASGGDaHTPVWQRIFWAGLMGVVAITLLLAGGLSALQTV 478
Cdd:PRK03356  397 TWAALPLSTATMWGFFILCFIATVTLINACsytlAMSTCREVRDGE-EPPLLVRIGWSILVGIIGIVLLALGGLKPIQTA 475
                         490       500
                  ....*....|....*....|....
gi 2314553684 479 TIASALPFAVVLLFSIYGLIKALR 502
Cdd:PRK03356  476 IIAGGCPLFFVNIMVTLSFIKDAK 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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