|
Name |
Accession |
Description |
Interval |
E-value |
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
2-724 |
0e+00 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 1545.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 2 MDPSLLLDGLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMG 81
Cdd:PRK11773 1 MDVSYLLDSLNDKQREAVAAPLGNMLVLAGAGSGKTRVLVHRIAWLMQVENASPYSIMAVTFTNKAAAEMRHRIEQLLGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 82 SASGMWNGTFHGICHRILRAHYLDAKLPEDFQIIDSDDQQRLLKRLIKAQNLDEKQWPARQVSWWINGKKDEGLRPNHID 161
Cdd:PRK11773 81 SQGGMWVGTFHGLAHRLLRAHWQDANLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAQWYINGQKDEGLRPQHIQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 162 AYHDPITQTYLQLYSAYQEACDRAGLVDFAEILLRAHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPD 241
Cdd:PRK11773 161 SYGDPVEQTWLKIYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYQERFTHILVDEFQDTNAIQYAWIRLLAGDT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 242 SHVMIVGDDDQSIYGWRGAKIENIEKFTLEFPSVNTIRLEQNYRSTKTILEASNTLIANNTERMGKELWTDGKEGEPISV 321
Cdd:PRK11773 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIANNNGRLGKELWTDGGDGEPISL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 322 YSAYNELDEARFAVNKIKEWQDKGGVLNDAAMLYRNNAQSRVLEEALIQAGLPYRIYGGMRFFERQEIKDALSYLRLMAN 401
Cdd:PRK11773 321 YCAFNELDEARFVVERIKTWQDNGGALSDCAILYRSNAQSRVLEEALLQAGIPYRIYGGMRFFERQEIKDALAYLRLIAN 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 402 RNDDAAFERVVNTPTRGLGDKTLETIRLAARERGCTMWDASKALLDEQVLPGRASGALSRFIELINALEDDTDEMSLHSQ 481
Cdd:PRK11773 401 RNDDAAFERVVNTPTRGIGDRTLDVVRQTARDRQLTLWQACRALLQEKVLAGRAASALQRFIELIDALAQETADMPLHEQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 482 TDHVIKYSGLFAMYEQEKGEKSKARIENLEELVTATRQFEKPEEADEMSMLTAFLTHAALEAGEGQADEFEDAVQLMTLH 561
Cdd:PRK11773 481 TDRVIKDSGLRAMYEQEKGEKGQARIENLEELVTATRQFSYPDEDEDLTPLQAFLSHAALEAGEGQADAHEDAVQLMTLH 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 562 SAKGLEFPLVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMQKLYITYAEMRRLYGQDKYHKPSRFIRELPEKC 641
Cdd:PRK11773 561 SAKGLEFPLVFIVGMEEGLFPSQMSLEEGGRLEEERRLAYVGITRAMQKLTLTYAESRRLYGKEVYHRPSRFIREIPEEC 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 642 LDEVRMKAQVSRPATSGRFSQTAVKEnfNETGFTLGSRVMHPKFGEGTIINFEGSGPQSRVQVAFNGEGIKWLVTAYAKL 721
Cdd:PRK11773 641 VEEVRLRATVSRPVSHQRMGTPAVEA--NDSGFKLGQRVRHPKFGEGTIVNFEGSGAHARVQVAFQGQGIKWLVAAYAKL 718
|
...
gi 2327038875 722 EKL 724
Cdd:PRK11773 719 EAV 721
|
|
| uvrD |
TIGR01075 |
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, ... |
7-722 |
0e+00 |
|
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130147 [Multi-domain] Cd Length: 715 Bit Score: 1315.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 7 LLDGLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMGSASGM 86
Cdd:TIGR01075 1 LLDGLNDKQREAVAAPPGNLLVLAGAGSGKTRVLTHRIAWLLSVENASPHSIMAVTFTNKAAAEMRHRIGALLGTSARGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 87 WNGTFHGICHRILRAHYLDAKLPEDFQIIDSDDQQRLLKRLIKAQNLDEKQWPARQVSWWINGKKDEGLRPNHIDAYHDP 166
Cdd:TIGR01075 81 WIGTFHGLAHRLLRAHHLDAGLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAMWYINNQKDEGLRPSHIQAFDNP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 167 ITQTYLQLYSAYQEACDRAGLVDFAEILLRAHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDSHVMI 246
Cdd:TIGR01075 161 VERTWIKIYQAYQEACDRAGLVDFAELLLRAHELLRNKPHILQHYQERFTHILVDEFQDTNKIQYAWIRLLAGNTGNVMI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 247 VGDDDQSIYGWRGAKIENIEKFTLEFPSVNTIRLEQNYRSTKTILEASNTLIANNTERMGKELWTDGKEGEPISVYSAYN 326
Cdd:TIGR01075 241 VGDDDQSIYGWRGAQVENIQKFLKDFPGAETIRLEQNYRSTANILAAANALIANNDERLGKNLWTDGEVGEPISLYSAFN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 327 ELDEARFAVNKIKEWQDKGGVLNDAAMLYRNNAQSRVLEEALIQAGLPYRIYGGMRFFERQEIKDALSYLRLMANRNDDA 406
Cdd:TIGR01075 321 ELDEARFVVSRIKTWQRNGGALDECAVLYRSNAQSRVLEEALLQASIPYRIYGGMRFFERQEIKDALAYLRLIANRNDDA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 407 AFERVVNTPTRGLGDKTLETIRLAARERGCTMWDASKALLDEQVLPGRASGALSRFIELINALEDDTDEMSLHSQTDHVI 486
Cdd:TIGR01075 401 AFERVINTPTRGIGDRTLDVVRQAARDRGLTLWQAARELTQEKVLAGRAASALQRFVELIEALANETADMPLHVQTDHVI 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 487 KYSGLFAMYEQEKGEKSKARIENLEELVTATRQFEKPEEADEMSMLTAFLTHAALEAGEGQADEFEDAVQLMTLHSAKGL 566
Cdd:TIGR01075 481 KDSGLREMYQQEKGEKGQARIENLEELVTATRQFSLPENDEDMTPLTAFLSHAALEAGEGQADAGQDAVQLMTLHSAKGL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 567 EFPLVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMQKLYITYAEMRRLYGQDKYHKPSRFIRELPEKCLDEVR 646
Cdd:TIGR01075 561 EFPLVFLVGMEEGMFPSQMSLDEGGRLEEERRLAYVGITRAMQKLTITYAETRRLYGKEVYHIPSRFIRELPEECLHEVR 640
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2327038875 647 MKAQVSRPATSGRFSQTAVKEnFNETGFTLGSRVMHPKFGEGTIINFEGSGPQSRVQVAFNGEGIKWLVTAYAKLE 722
Cdd:TIGR01075 641 LRAQVSRPTNLGRVGTPSVDE-INDAGFKLGQRVRHPKFGEGTIINAEGSGEHSRLQIAFQGQGIKWLVAAYAKLE 715
|
|
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
7-715 |
0e+00 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 943.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 7 LLDGLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMGSASGM 86
Cdd:COG0210 3 LLAGLNPEQRAAVEHPEGPLLVLAGAGSGKTRVLTHRIAYLIAEGGVDPEQILAVTFTNKAAREMRERIEALLGRLARGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 87 WNGTFHGICHRILRAHYLDAKLPEDFQIIDSDDQQRLLKRLIKAQNLDEKQWPARQVSWWINGKKDEGLRPNHIDAY--H 164
Cdd:COG0210 83 WVGTFHSLALRILRRHAELLGLPPNFTILDGDDQLRLIKELLKELGLDEKRFPPRELLSLISRAKNEGLTPEELAELlaA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 165 DPITQTYLQLYSAYQEACDRAGLVDFAEILLRAHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDSHV 244
Cdd:COG0210 163 DPEWRAAAELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVDEYQDTNPAQYELLRLLAGDGRNL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 245 MIVGDDDQSIYGWRGAKIENIEKFTLEFPSVNTIRLEQNYRSTKTILEASNTLIANNTERMGKELWTDGKEGEPISVYSA 324
Cdd:COG0210 243 CVVGDDDQSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANNPGRLGKNLWTDNGEGEKVRLYVA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 325 YNELDEARFAVNKIKEWQDKGGVLNDAAMLYRNNAQSRVLEEALIQAGLPYRIYGGMRFFERQEIKDALSYLRLMANRND 404
Cdd:COG0210 323 PDEEEEARFVADEIRELHEEGVPLSDIAVLYRTNAQSRALEEALRRAGIPYRVVGGLRFYERAEIKDLLAYLRLLANPDD 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 405 DAAFERVVNTPTRGLGDKTLETIRLAARERGCTMWDASKALLDEQVLPGRASGALSRFIELINALEDDTDEMSLHSQTDH 484
Cdd:COG0210 403 DVALLRILNVPRRGIGAATLERLREAAREEGISLLEALRDLGELAGLSGRAAKALRRFAELLEALRAAAERLPLEELLEA 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 485 VIKYSGLFAMYEQEKGEKSKARIENLEELVTATRQFekpEEADEMSMLTAFLTHAALEAGEGQADEFEDAVQLMTLHSAK 564
Cdd:COG0210 483 LLDESGYEEELREEAGEEAERRLENLEELVDAAARF---EERNPGASLEAFLEELALLSDLDAADEDEDAVTLMTLHAAK 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 565 GLEFPLVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMQKLYITYAEMRRLYGQDKYHKPSRFIRELPEKCLDE 644
Cdd:COG0210 560 GLEFPVVFLVGLEEGLFPHQRSLDDEEELEEERRLFYVAITRARERLYLTYAASRRLWGETQDNEPSRFLDELPEELLEW 639
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2327038875 645 VRMKAQVSRPATSGRFSQTAVKENFNE-------TGFTLGSRVMHPKFGEGTIINFEGSGPQSRVQVAFNGEGIKWLV 715
Cdd:COG0210 640 VRPKAEAAAAAASAAAALPASGAGAAAlaagaaaAAAAAGGGAAVAGAGLGRAAAAGGADGGAAGAGGGLAAVALTVL 717
|
|
| pcrA |
TIGR01073 |
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. ... |
7-722 |
0e+00 |
|
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273429 [Multi-domain] Cd Length: 726 Bit Score: 749.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 7 LLDGLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMGSASGM 86
Cdd:TIGR01073 1 LLAHLNPEQREAVKTTEGPLLIMAGAGSGKTRVLTHRIAHLIAEKNVAPWNILAITFTNKAAREMKERVEKLLGPVAEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 87 WNGTFHGICHRILRAHYLDAKLPEDFQIIDSDDQQRLLKRLIKAQNLDEKQWPARQVSWWINGKKDEGLRPNHI----DA 162
Cdd:TIGR01073 81 WISTFHSMCVRILRRDIDRIGINRNFSIIDPTDQLSLMKTILKDKNLDPKKFEPRSILGTISNAKNELLPPEDFakeaTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 163 YHDpitQTYLQLYSAYQEACDRAGLVDFAEILLRAHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDS 242
Cdd:TIGR01073 161 YFE---KVVAEVYQEYQKRLLRNNALDFDDLIMTTINLFQRVPDVLEYYQRKFQYIHVDEYQDTNRAQYTLVRLLASRFR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 243 HVMIVGDDDQSIYGWRGAKIENIEKFTLEFPSVNTIRLEQNYRSTKTILEASNTLIANNTERMGKELWTDGKEGEPISVY 322
Cdd:TIGR01073 238 NLCVVGDADQSIYGWRGADIQNILSFEKDYPNATTILLEQNYRSTKNILQAANEVIEHNSNRKPKNLWTENSSGDKITYY 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 323 SAYNELDEARFAVNKIKEWQDKGGV-LNDAAMLYRNNAQSRVLEEALIQAGLPYRIYGGMRFFERQEIKDALSYLRLMAN 401
Cdd:TIGR01073 318 EADTERDEAQFVAGEIDKLVKNGERkYGDFAILYRTNAQSRVFEETLLKANIPYKIVGGLKFYDRKEIKDILAYLRVIAN 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 402 RNDDAAFERVVNTPTRGLGDKTLETIRLAARERGCTMWDASKALLDEQVLPGRASGALSRFIELINALEDDTDEMSLHSQ 481
Cdd:TIGR01073 398 PDDDLSLLRIINVPKRGIGASSLEKIVNYALELNISLFEAIGEIDEIGGLAAKSANALLAFATMIENLRQQQEYLSPTEL 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 482 TDHVIKYSGLFAMYEQEKGEKSKARIENLEELVTATRQFEkpEEADEMSmLTAFLTHAALEAGEGQADEFE--DAVQLMT 559
Cdd:TIGR01073 478 VEEVLDKSGYREMLKAEKTEEAQSRLENLDEFLSVTKEFE--DESEDKS-LIDFLTDLALVSDLDELEETEegGAVTLMT 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 560 LHSAKGLEFPLVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMQKLYITYAEMRRLYGQDKYHKPSRFIRELPE 639
Cdd:TIGR01073 555 LHAAKGLEFPVVFLIGMEEGVFPHSRSLMDEKELEEERRLAYVGITRAEEELYLTHATMRTLFGRIQMNPPSRFLNEIPA 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 640 KCLDEVR---------------MKAQVSRPATSGrfSQTAVKenfnETGFTLGSRVMHPKFGEGTIINFEGSGPQSRVQV 704
Cdd:TIGR01073 635 ELLETAStgrrtgatdpkgpsiRQAGASRPTTSQ--PTAGGD----TLSWAVGDRVNHKKWGIGTVVSVKGGGDDQELDI 708
|
730
....*....|....*...
gi 2327038875 705 AFNGEGIKWLVTAYAKLE 722
Cdd:TIGR01073 709 AFPSIGVKRLLAAFAPIE 726
|
|
| rep |
TIGR01074 |
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. ... |
10-652 |
5.85e-180 |
|
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130146 [Multi-domain] Cd Length: 664 Bit Score: 528.94 E-value: 5.85e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 10 GLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRI-EELMMGSASGMWN 88
Cdd:TIGR01074 1 KLNPQQQEAVEYVTGPCLVLAGAGSGKTRVITNKIAYLIQNCGYKARNIAAVTFTNKAAREMKERVaKTLGKGEARGLTI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 89 GTFHGICHRILRAHYLDAKLPEDFQIIDSDDQQRLLKRLIKAQNLDEK---QWPARQVSWWingkKDEGLRPNHIDAY-H 164
Cdd:TIGR01074 81 STFHTLGLDIIKREYNALGYKSNFSLFDETDQLALLKELTEGLIKDDKdllDKLISTISNW----KNDLLTPEQALASaR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 165 DPITQTYLQLYSAYQEACDRAGLVDFAEILLRAHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDSHV 244
Cdd:TIGR01074 157 GEREQTFAHCYALYQAHLRAYNALDFDDLILLPTLLLQQNEEVRNRWQNKIRYLLVDEYQDTNTSQYELVKLLVGDRARF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 245 MIVGDDDQSIYGWRGAKIENIEKFTLEFPSVNTIRLEQNYRSTKTILEASNTLIANNTERMGKELWTDGKEGEPISVYSA 324
Cdd:TIGR01074 237 TVVGDDDQSIYSWRGARPENLVLLKEDFPQLKVIKLEQNYRSTGRILKAANILIANNPHVFEKKLFSELGYGEKIKVIEC 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 325 YNELDEA-RFAVNKIKEWQDKGGVLNDAAMLYRNNAQSRVLEEALIQAGLPYRIYGGMRFFERQEIKDALSYLRLMANRN 403
Cdd:TIGR01074 317 NNEEHEAeRIAGEIIAHKLVNKTQYKDYAILYRGNHQSRLLEKALMQNRIPYKLSGGTSFFSRPEIKDLLSYLRLLVNPD 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 404 DDAAFERVVNTPTRGLGDKTLETIRLAARERGCTMWDASKALLDEQVLPGRASGALSRFIELINALEDDTDEMSLHSQTD 483
Cdd:TIGR01074 397 DDAAFLRIVNTPKREIGPATLEKLGELAMERNKSLFTASFDMGLLQTLSGRGYESLQRFTDWLVEIRRLAERSEPIEAVR 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 484 ---HVIKYsgLFAMYEQEKGEKS-KARIENLEELVTA-TRQFEKPEEADEMSMLTAFLTHAALEAGEGQADEFE-DAVQL 557
Cdd:TIGR01074 477 sliEDIDY--ENWLYETSPSPKAaEMRMKNVNTLFSWfKEMLEGDEEDEPMTLTQVVTRLTLRDMLERGEDEEElDQVQL 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 558 MTLHSAKGLEFPLVFMVGVEEGMFPSQMSAEEaGRLEEERRLCYVGMTRAMQKLYITYAEMRRLYGQDKYHKPSRFIREL 637
Cdd:TIGR01074 555 MTLHASKGLEFPYVFIVGMEEGILPHQSSIEE-DNVEEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLDEL 633
|
650
....*....|....*
gi 2327038875 638 PEKCLDEVRMKAQVS 652
Cdd:TIGR01074 634 PQEDLQWEGDDPVVS 648
|
|
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
11-639 |
1.22e-143 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 435.81 E-value: 1.22e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 11 LNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRIEELM-MGSASGMWNG 89
Cdd:PRK10919 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVAQTLgRKEARGLMIS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 90 TFHGICHRILRAHYLDAKLPEDFQIIDSDDQQRLLKRLIKAQNLDEKQWPARQVSWWINGKKDEGLRPNHIDAYHDPITQ 169
Cdd:PRK10919 83 TFHTLGLDIIKREYAALGMKSNFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAGAKGERDR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 170 TYLQLYSAYQEACDRAGLVDFAEILLRAHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDSHVMIVGD 249
Cdd:PRK10919 163 IFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGD 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 250 DDQSIYGWRGAKIENIEKFTLEFPSVNTIRLEQNYRSTKTILEASNTLIANNTERMGKELWTDGKEGEPISVYSAYNELD 329
Cdd:PRK10919 243 DDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVLSANNEEH 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 330 EARFAVNK------IKEWQDKggvlnDAAMLYRNNAQSRVLEEALIQAGLPYRIYGGMRFFERQEIKDALSYLRLMANRN 403
Cdd:PRK10919 323 EAERVTGEliahhfVNKTQYK-----DYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPD 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 404 DDAAFERVVNTPTRGLGDKTLETIRLAARERGCTMWDASKALLDEQVLPGRASGALSRFIELINALEDDTDEMSLHSQTD 483
Cdd:PRK10919 398 DDSAFLRIVNTPKREIGPATLQKLGEWAMTRNKSLFTASFDMGLSQTLSGRGYESLTRFTHWLAEIQRLAEREPVAAVRD 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 484 --HVIKYSGLfaMYEQEKGEK-SKARIENLEELVTATRQFEKPEEADEMSMLTAFLTHAALE--AGEGQADEFEDAVQLM 558
Cdd:PRK10919 478 liHGIDYESW--LYETSPSPKaAEMRMKNVNQLFSWMTEMLEGSELDEPMTLTQVVTRFTLRdmMERGESEEELDQVQLM 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 559 TLHSAKGLEFPLVFMVGVEEGMFPSQMSAEEaGRLEEERRLCYVGMTRAMQKLYITYAEMRRLYGQDKYHKPSRFIRELP 638
Cdd:PRK10919 556 TLHASKGLEFPYVYLVGMEEGLLPHQSSIDE-DNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELP 634
|
.
gi 2327038875 639 E 639
Cdd:PRK10919 635 Q 635
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
11-273 |
1.54e-110 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 335.75 E-value: 1.54e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 11 LNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMGS-ASGMWNG 89
Cdd:pfam00580 1 LNPEQRKAVTHLGGPLLVLAGAGSGKTRVLTERIAYLILEGGIDPEEILAVTFTNKAAREMKERILKLLGKAeLSELNIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 90 TFHGICHRILRAHYLDAKLPEDFQIIDSDDQQRLLKRLIKAQ--NLDEKQWPARQVSWWINGKKDEGLRPNHIDAYH-DP 166
Cdd:pfam00580 81 TFHSFCLRILRKYANRIGLLPNFSILDELDQLALLKELLEKDrlNLDPKLLRKLELKELISKAKNRLLSPEELQQGAaDP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 167 ITQTYLQLYSAYQEACDRAGLVDFAEILLRAHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDSHVMI 246
Cdd:pfam00580 161 RDKLAAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPIQYRLLKLLAGGHENLFL 240
|
250 260
....*....|....*....|....*..
gi 2327038875 247 VGDDDQSIYGWRGAKIENIEKFTLEFP 273
Cdd:pfam00580 241 VGDPDQSIYGFRGADIENILKFEKDFP 267
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
1-636 |
3.34e-108 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 348.88 E-value: 3.34e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 1 MMDPSLlldglNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRI----- 75
Cdd:COG1074 1 MSEPPW-----TDAQRRALDPLGGSVLVEASAGSGKTYTLVARYLRLLLERGLDPEEILVVTFTRAAAAEMRERIrerla 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 76 EELMMGSASGMWN-------------------GTFHGICHRILRAHYLDAKLPEDFQIIDSDDQ---------------- 120
Cdd:COG1074 76 EAADLEDPDLEELararrrlaralenldraaiSTIHSFCQRLLREFAFEAGLDPNFELLDDAEAllleeavddllreaya 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 121 ---------------------QRLLKRLIKAQNldEKQWPARQVSWWINGKKDEGLRPNHIDAYHDPITQTYLQLYS--- 176
Cdd:COG1074 156 pldalalarlldafgrdddslEELLLALYKLRS--RPDWLEELAELDEALEALREALLKAKEALAALREALAAAAAPlla 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 177 -----------AYQEACDRAGLVDFAEILLRAHELLRDKKH--IREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDSH 243
Cdd:COG1074 234 allrllaavlaRYERRKRERGLLDFDDLLHRALRLLRDEDApwVAERLRERYRHILVDEFQDTSPLQWEILRRLAGEALA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 244 ----VMIVGDDDQSIYGWRGAKIENIEKFTLEF---PSVNTIRLEQNYRSTKTILEASNTL--------------IANNT 302
Cdd:COG1074 314 dgrtLFLVGDPKQSIYRFRGADPELFLEARRALegrVDGERLTLTTNFRSTPEVVDAVNALfaqlmgagfgeipyEPVEA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 303 ERMGK----ELWTDGKEGEPISVYSAYneldEARFAVNKIKEWQDKGGVLN---------DAAMLYRNNAQSRVLEEALI 369
Cdd:COG1074 394 LRPGAypavELWPLEPDDVSEEDARER----EARAVAARIRRLLAEGTTVEgggrpvrpgDIAVLVRTRSEAAAIARALK 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 370 QAGLPYRIYGGMRFFERQEIKDALSYLRLMANRNDDAAFERVVNTPTRGLGDKTLEtiRLAARERGCTMWDAskalldeq 449
Cdd:COG1074 470 AAGIPVAASDRLSLFESPEVRDLLALLRALLNPEDDLALAAVLRSPLFGLSDEDLA--ALAADRKGESLWEA-------- 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 450 vLpgRASGALSRFIELINALEDDTDEMSLHSQTDHVIKYSGLFAMY-EQEKGEKSKARIENLEELVTATRQFEKPEEADE 528
Cdd:COG1074 540 -L--RAYERLARALERLRALRELARRLGLAELLERLLEETGLLERLlALPGGERRLANLLHLDELLQLALEYEQTGGPGL 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 529 MSMLtAFLTHAALEAGEGQA---DEFEDAVQLMTLHSAKGLEFPLVFMvgveegmfPSQMSAEEAGRLEEERRLCYVGMT 605
Cdd:COG1074 617 AGFL-RWLERLIEDGGDEEKrrlESDADAVRIMTIHKSKGLEFPVVFL--------PALRERARAEELAEELRLLYVALT 687
|
730 740 750
....*....|....*....|....*....|.
gi 2327038875 606 RAMQKLYITYAEmrrlyGQDKYHKPSRFIRE 636
Cdd:COG1074 688 RARDRLVLSGAV-----KKKDAEKESSWLAR 713
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
278-617 |
1.31e-93 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 295.85 E-value: 1.31e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 278 IRLEQNYRSTKTILEASNTLIANNTERM----GKELWTDGKEGEPISVYSAYNELDEARFAVNKIKEWQDKGGVLNDAAM 353
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRAtiypKKILAETVEDGEKIKIIEAETEEEEAEWIALEIKKLVARDEKYNDIAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 354 LYRNNAQSRVLEEALIQAGLPYRIYGGMRFFERQEIKDALSYLRLMANRNDDAAFERVVNTPTRGLGDKTLETIR----- 428
Cdd:pfam13361 81 LTRSNSDADLIEEALKKLGIPYFVVGQTKFFRREEIKDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERIReykkr 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 429 ------LAARERGCTMWDASKALLDEQV------------------------LPGRA--SGALSRFIELINALEDDTdem 476
Cdd:pfam13361 161 glrlsdFINPDTLTYGDPFVIALEQDNIvvfdvettgldttedeiiqiaaikLNKKGvvIESFERFLRLKKPVGDSL--- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 477 slhsqtdHVIKYSGLFamyEQEKGEKSKA-------RIENLEELVTATRQFEKPEEADEMSM-LTAFLTHAALEAGEGQA 548
Cdd:pfam13361 238 -------QVHGFSDEF---LQENGETPAEalrdfleKLENLRELYSILREYDDIEETPEPEDaLRNFLEIATLSNSELEG 307
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2327038875 549 DEFEDAVQLMTLHSAKGLEFPLVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMQKLYITYAE 617
Cdd:pfam13361 308 SDIKERIPIMTIHQAKGLEFDTVFLAGLEEGIFPSYRSIKDEGNLEEERRLFYVAITRAKKRLYISYSK 376
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
12-284 |
3.86e-83 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 261.30 E-value: 3.86e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 12 NDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMG-SASGMWNGT 90
Cdd:cd17932 1 NPEQREAVTHPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGVPPERILAVTFTNKAAKEMRERLRKLLGEqLASGVWIGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 91 FHGICHRILRAHYldaklpedfqiidsddqqrllkrlikaqnldekqwparqvswwingkkdeglrpnhidayhdpitqt 170
Cdd:cd17932 81 FHSFALRILRRYG------------------------------------------------------------------- 93
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 171 ylqlysayqeacdraglvDFAEILLRAHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDSHVMIVGDD 250
Cdd:cd17932 94 ------------------DFDDLLLYALELLEENPDVREKLQSRFRYILVDEYQDTNPLQYELLKLLAGDGKNLFVVGDD 155
|
250 260 270
....*....|....*....|....*....|....
gi 2327038875 251 DQSIYGWRGAKIENIEKFTLEFPSVNTIRLEQNY 284
Cdd:cd17932 156 DQSIYGFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| addA_Gpos |
TIGR02785 |
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, ... |
13-613 |
2.03e-35 |
|
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274299 [Multi-domain] Cd Length: 1230 Bit Score: 144.46 E-value: 2.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 13 DKQREAVAAPLENLLILAGAGSGKTRVLVHRIawlmsVEQ-ASPFSI---MSVTFTNKAAAEMRGRIEELM--------- 79
Cdd:TIGR02785 4 DEQWQAIYTRGQDILVSASAGSGKTAVLVERI-----IRKiTRGVDVdrlLVVTFTNAAAREMKERIAEALekelvqepn 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 80 ----------MGSASgmwNGTFHGICHRILRAHY------------------------LDAKLPEDFQIID--------- 116
Cdd:TIGR02785 79 skhlrrqlalLNTAN---ISTLHSFCLKVIRKHYylldldpsfriltdteqlllikevLDDVFEEEYYKEDkeaffelvd 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 117 ------SDDQ-QRLLKRL-------------------------------------IK----------------------- 129
Cdd:TIGR02785 156 nfsgdrSDDGlRDLILQLydfsrstpnpekwlnnlaeayevkekftieslklqqqIKellkneleglqeklqralelfma 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 130 --------------AQNLDEK-QWPARQVSW-----------WINGK---KDEGLRP----------------------- 157
Cdd:TIGR02785 236 edglaprlenfqldLQNIDELiQESLAQADWnelrkavaafkFKNLKaakGDEEDADlleeadklreeakkqleklktdy 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 158 ------NHIDAYHD--PITQTYLQLYS----AYQEACDRAGLVDFAEILLRAHELL----RDKKHIREHYQARFKHILVD 221
Cdd:TIGR02785 316 ftrseeDHLRIMQEmkPVVKTLVQLVKdfieRFGAEKREKNILDFSDLEHYALQILtnenESPSEAAEFYREKFHEVLVD 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 222 EFQDTNNIQYAWLRMMAGPDSH---VMIVGDDDQSIYGWRGAK----IENIEKFTLEFPSVNT-IRLEQNYRSTKTILEA 293
Cdd:TIGR02785 396 EYQDTNLVQESILQLVKRGPEEegnLFMVGDVKQSIYRFRQADpllfLEKYHRFAQEGEEHGKrIDLAENFRSRAEVLDT 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 294 SNTL------------------------------IANNTERMGKELWTDGKEGEPiSVYSAYNELDEARFAVNKI----- 338
Cdd:TIGR02785 476 TNFLfkqlmdeevgeidydeeaqlkfgaakypenPDNKTEELLYEKLLIEEAEEE-EIDEEAEILDKAQQEATMVaerik 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 339 ------------KEWQDKGGVLNDAAMLYRNNAQSRVLEEALIQAGLPYRIYGGMRFFERQEIKDALSYLRLMANRNDDA 406
Cdd:TIGR02785 555 alikegfkvydkKTGTYRPVTYRDIVILTRSRGWNLQIMEEFKKYGIPVFANDAENYFQTTEVRVMLSLLRVIDNPYQDI 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 407 AFERVVNTPTRGLGDKTLETIRLAARERgcTMWDASKALLDEQVLPGRASGALSRFIELINALEDDTDEMSL-------H 479
Cdd:TIGR02785 635 PLVAVLRSPIVGFDENELALIRLENKDS--SYYEAVKDYVKAGLIEDELYEKLNTFLDSLQKWREFARTHSVseliwkiY 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 480 SQTDHVIKYSGLFAmyeqekgekSKARIENLEELVTATRQFEKpeeademsmlTAF--------LTHAALEAGE--GQA- 548
Cdd:TIGR02785 713 NDTGYYDYVGGLPG---------GKQRQANLYALYERARQYES----------TSFkglfqfirFIERMQERQKdlASAv 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 549 --DEFEDAVQLMTLHSAKGLEFPLVFMVGV-----------------------------EEGMFPSQmsAEEAGR----- 592
Cdd:TIGR02785 774 avGEAENAVRLMTIHKSKGLEFPVVFVLGMgkqfnkqdlnssylldrqlglgikyidpqERLSYPSL--PKVAIKqkmkr 851
|
890 900
....*....|....*....|...
gi 2327038875 593 --LEEERRLCYVGMTRAMQKLYI 613
Cdd:TIGR02785 852 elLSEEMRVLYVALTRAKEKLIL 874
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
286-615 |
1.00e-31 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 120.80 E-value: 1.00e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 286 STKTILEASNTLIANNTERMGKELWTDGKEGEPISVYSAYNELDEARFAVNKIKEWQDKGGV-LNDAAMLYRNNAQSRVL 364
Cdd:cd18807 1 STKNILDAANSLIKQNKNRPKKPLKAGNKSGGPVELLLAKDEADEAKAIADEIKRLIESGPVqYSDIAILVRTNRQARVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 365 EEALIqaglpyriyggmrfferqeikdalsylrlmanrnddaafervvntptrglgdktletirlaarergctmwdaska 444
Cdd:cd18807 81 EEALR--------------------------------------------------------------------------- 85
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 445 lldeqvlpgrasgalsrfielinaleddtdemslhsqtdhvikysglfamyeqekgekskarienleelvtatrqfekpe 524
Cdd:cd18807 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 525 eademsmltaflthaaleagegqadefedaVQLMTLHSAKGLEFPLVFMVGVEEGMFPSQMSAEEAG----RLEEERRLC 600
Cdd:cd18807 86 ------------------------------VTLMTIHASKGLEFPVVFIVGLGEGFIPSDASYHAAKedeeRLEEERRLL 135
|
330
....*....|....*
gi 2327038875 601 YVGMTRAMQKLYITY 615
Cdd:cd18807 136 YVALTRAKKELYLVG 150
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
11-314 |
7.50e-28 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 119.67 E-value: 7.50e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 11 LNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRGRIEELMmgSASGMWNGT 90
Cdd:PRK11054 197 LNPSQARAVVNGEDSLLVLAGAGSGKTSVLVARAGWLLARGQAQPEQILLLAFGRQAAEEMDERIRERL--GTEDITART 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 91 FHGICHRILRAhyLDAKLPEdFQIIDSDDQQRlLKRLIKA--QNLDEK--------QWPARQVSW-------WINGKKDE 153
Cdd:PRK11054 275 FHALALHIIQQ--GSKKVPV-ISKLENDSKAR-HALLIAEwrKQCSEKkaqakgwrQWLTEELQWdvpegnfWDDEKLQR 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 154 GLRP--------------------NHIDAYHDPITQTYLQL----YSAYQEACDRAGLVDFAEILLRAHELLRDKKHIRE 209
Cdd:PRK11054 351 RLASrlerwvslmrmhggsqaemiAQAPEEVRDLFQKRLKLmaplLKAWKKALKAENAVDFSGLIHQAVNYLEKGRFISP 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 210 hyqarFKHILVDEFQDtnnIQYAWLRMMAG-----PDSHVMIVGDDDQSIYGWRGAKIENIEKFTLEFPSVNTIRLEQNY 284
Cdd:PRK11054 431 -----WKHILVDEFQD---ISPQRAALLAAlrkqnSQTTLFAVGDDWQAIYRFSGADLSLTTAFHERFGEGDRCHLDTTY 502
|
330 340 350
....*....|....*....|....*....|..
gi 2327038875 285 RSTKTILEASNTLIANNTERMGKEL--WTDGK 314
Cdd:PRK11054 503 RFNSRIGEVANRFIQQNPHQLKKPLnsLTKGD 534
|
|
| recB |
TIGR00609 |
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with ... |
27-617 |
2.90e-27 |
|
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with potent ATP-dependent exodeoxyribonuclease activity. Ejection of RecD, as occurs at chi recombinational hotspots, cripples exonuclease activity in favor of recombinagenic helicase activity. All proteins in this family for which functions are known are DNA-DNA helicases that are used as part of an exonuclease-helicase complex (made up of RecBCD homologs) that function to generate substrates for the initiation of recombination and recombinational repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273172 [Multi-domain] Cd Length: 1087 Bit Score: 118.69 E-value: 2.90e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 27 LILAGAGSGKTRV---LVHRIawLMSVEQASPFSIMSVTFTNKAAAEMRGRI---------------------EELMMGS 82
Cdd:TIGR00609 13 LIEASAGTGKTFTiaqLYLRL--LLEGGPLTVEEILVVTFTNAATEELKTRIrgrihqalralkaaltsqelpEPLKEAI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 83 ASGMWNG------------------TFHGICHRILRAHYLDAKLPEDFQIIDSDD----------------------QQR 122
Cdd:TIGR00609 91 QDEKVKQaitrlrnalatmdeaaiyTIHGFCQRMLEQHAFESDEIFDVELIEDESlllaeitkdfwrrnfynlpfdiAQI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 123 LLKRLIKAQNL--DEKQWPARQVSWWINGK--KDEGLRPNHIDAYHDPITQTY----------------------LQLYS 176
Cdd:TIGR00609 171 VLKTKKSPQAVltQILADLLLQSYLAFPSPplDLEQLIKWHEQIYKDLDKLDHavfeeidklnaernnlfclkdrVFLTL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 177 A------YQEACDRAGLVDFAEILLRAHELLRDKKH------IREHYQArfkhILVDEFQDTNNIQYAWL-RMMAGPDSH 243
Cdd:TIGR00609 251 LkevqeeLKKEKKRRREIGFDDLLSRLETALKSAEGeklaqaIREQYPI----ALIDEFQDTDPQQYRIFsKLFIAQKET 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 244 VMI-VGDDDQSIYGWRGAKIENIEKFTLEFPSVNTirLEQNYRSTKTILEASNTLIANNTERM------------GKE-- 308
Cdd:TIGR00609 327 SLFlIGDPKQAIYSFRGADIFTYLQAKSKADARYT--LGTNWRSTPALVGSLNKLFSLISNPFlekpifipvlahQKNsk 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 309 --LWTDGKEGEPISVYSAYNE--------LDEARFAVNKIKEW-----------QDKGG----VLNDAAMLYRNNAQSRV 363
Cdd:TIGR00609 405 gsFVINGQEQPPIHFFTTEVEsegvddyrQTIAQKCAREIALWlasaalglanfIATFGgrplRAGDIAVLVRGRKEANQ 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 364 LEEALIQAGLPyRIYGGMR--FFERQEIKDALSYLR-LMANRNDdaafervvntptrglgdktlETIRLAArergctmwd 440
Cdd:TIGR00609 485 IRKALKKAQIP-SVYLSDKssVFATEEAQELLALLEaLLEPENE--------------------GTLRAAL--------- 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 441 ASKALldeqvlpgrasGALSRFIELINALEDDTDEMSLHSQT--DHVIKYsGLFAMY--------------EQEKGEKSK 504
Cdd:TIGR00609 535 ASSIF-----------GLSALELETLNQDEITWERVVEKFREyhDIWRKI-GVLAMFqrlmlekgigerllSQPGGERIL 602
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 505 ARIENLEELVTATRQFEKpeeaDEMSMLTAFLTHAALE-AGEGQA---DEFEDAVQLMTLHSAKGLEFPLVFMVGV---- 576
Cdd:TIGR00609 603 TNLLHLAELLQEAAHQER----NKLSLLRWLEDQISNEeEEEEEIirlESDAELVKIVTIHKSKGLEYPIVFLPFItdak 678
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 2327038875 577 -------------EEGMFPSQMSAEEAG-----RLEEERRLCYVGMTRAMQKLYITYAE 617
Cdd:TIGR00609 679 ksnfaslhdqhshEYQLYDFNQSEENQKlarveRLAEDLRLLYVALTRAKKQLFIGIAP 737
|
|
| addA_alphas |
TIGR02784 |
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, ... |
167-614 |
3.44e-27 |
|
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274298 [Multi-domain] Cd Length: 1135 Bit Score: 118.25 E-value: 3.44e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 167 ITQTYLQLYSAYQEAcdrAGLVDFAEILLRAHELLRDKKhirEHYQARFK------HILVDEFQDTNNIQYAWLRMMA-- 238
Cdd:TIGR02784 343 LAARLLQRYARLKKA---RGLLDFNDLIERTVALLARPG---AGAWVHYKldrgidHILVDEAQDTSPEQWDIIQALAee 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 239 ---------GPDSHVMIVGDDDQSIYGWRGAKIENIEKFTLEFPS--------VNTIRLEQNYRSTKTILEASNTLIANN 301
Cdd:TIGR02784 417 ffsgegarsGVERTIFAVGDEKQSIYSFQGADPERFAEERREFSRkvravgrkFEDLSLNYSFRSTPDVLAAVDLVFADP 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 302 TERMG----------------------------------KELWTDGKEGEPISvySAYNELDEARFAVnkIKEWQDKGGV 347
Cdd:TIGR02784 497 ENARGlsadsdapvheafrddlpgrvdlwdliskeegeePEDWTDPVDELGER--APEVRLAERIAAE--IRAWLDRGTP 572
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 348 L---------NDAAMLYRNNAQsrvLEEALIQA----GLPyrIYGGMRFFERQEI--KDALSYLRLMANRNDDAAFERVV 412
Cdd:TIGR02784 573 IpgrgravrpGDILVLVRKRDA---FFSALIRAlkrrGIP--VAGADRLKLTSHIavKDLMALGRFVLQPEDDLSLAALL 647
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 413 NTPTRGLGDKTLetIRLAARERGCTMWDASkalldeqvlpGRASGALSRFIELINALEDDTDEMSLHSqtdhvikysgLF 492
Cdd:TIGR02784 648 KSPLFGLDEDDL--FRLAAGRSGGSLWAAL----------RRREAEFAATLAVLRDWLSLADFLTPFE----------FY 705
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 493 AMYEQEKGEKSK--ARI-----ENLEELVTATRQFEKPEEADemsmLTAFLthAALEAGE----GQADEFEDAVQLMTLH 561
Cdd:TIGR02784 706 ARLLGRDGGRRKllARLgaeaeDILDEFLSQALAYERTGLPG----LQAFL--SWLEADDpeikREMDQARDEVRVMTVH 779
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 562 SAKGLEFPLVFMVGVEEGMFPSQ---------------------------MSAEEAGRL-----EEERRLCYVGMTRAMQ 609
Cdd:TIGR02784 780 GAKGLEAPVVFLVDTGSKPFASQraplllatggsggkaplwrpasafdpsLSAAARERLkeraeDEYRRLLYVAMTRAED 859
|
....*
gi 2327038875 610 KLYIT 614
Cdd:TIGR02784 860 RLIVC 864
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
27-639 |
1.57e-26 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 116.38 E-value: 1.57e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 27 LILAGAGSGKTRVLVHRIAWLMsvEQASPFsIMSVTFTNKAAAEmrgrIEELMMGSASGMWNG---TFHGICHRILRAHY 103
Cdd:COG3857 2 FILGRAGSGKTTYLLEEIKEEL--KEGKPI-ILLVPEQMTFQAE----RALLKRLGLGGSIRAqvlSFSRLAWRVLQETG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 104 LDAKlpedfQIIDSDDQQRLLKRLIK--AQNL----DEKQWP--ARQVSWWINGKKDEGLRPNHIDAYHDPITQTYLQL- 174
Cdd:COG3857 75 GATR-----PLLSDAGKRMLLRKILEehKDELkvfaRAADKPgfIEQLAELITELKRYGITPEDLEEAAELLKEKLRDLa 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 175 --YSAYQEACdRAGLVDFAEILLRAHELLRDKKHIREHyqarfkHILVDEFQDTNNIQYAWLRMMAGPDSHVMI---VGD 249
Cdd:COG3857 150 liYEAYEEKL-AGRYIDSEDLLRLLAEKLEKSEFLEGA------EIYIDGFTDFTPQELELLEALLKKAKEVTItltLDP 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 250 DDQSIYGWRGAKIENIEKFTLEfpsvntIRLEQNYRSTKTILEASNTLIANNTErmgkelwtdgKEGEPISVYSAYNELD 329
Cdd:COG3857 223 DELDLFSATGETYERLLELAKE------NGVEVEFKKSPELAHLERNLFAYPPE----------EEPEGIEIIEAANRRA 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 330 EARFAVNKIKEWQDKGGV-LNDAAMLYRN-NAQSRVLEEALIQAGLPYRIYGGMRFFERQEIKDALSYLRLMANRNDDAA 407
Cdd:COG3857 287 EVEAVAREIRRLVREEGYrYRDIAVVVRDlEAYAPLIERVFAEYGIPYFIDEKRPLSHHPLVELILSLLELVRSNFRYED 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 408 FERVVNTP-TRGLGDKTLETIRLAARERGCTMWDASKALLDEQVLPG--------RASGALSRFIELINALEDDTDEM-S 477
Cdd:COG3857 367 VFRLLKTGlLRPLSREEIDRLENYVLAYGIRGRRWLERYLEEEEELTdeeeedleRLNELRDRLLEPLLPLRERLKKAkT 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 478 LHSQTD---HVIKYSGLFAMYEQEKGEKSKARIENLEE-------LVTATRQFEKPEEADEMSMLTAF--LTHAALEAGE 545
Cdd:COG3857 447 VREWAEalyEFLEELGVPEKLEEWREAEEAGDLEEAREheqawnaLIELLDELVEVLGDEKLSLEEFLriLESGLEELTF 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 546 GQADEFEDAVQLMTLHSAKGLEFPLVFMVGVEEGMFPSQMSAE------------EAG---------RLEEERRLCYVGM 604
Cdd:COG3857 527 GLIPPSLDQVQVGGLDRARGLDFKAVFVLGLNEGVFPARPREDgllsdeererlnELGlelpptsreRLLEERFLFYRAL 606
|
650 660 670
....*....|....*....|....*....|....*
gi 2327038875 605 TRAMQKLYITYAEMRRlygQDKYHKPSRFIRELPE 639
Cdd:COG3857 607 TRASERLYLSYPLADE---EGKALLPSPLIDRLRE 638
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
25-284 |
2.96e-20 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 86.77 E-value: 2.96e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 25 NLLILAGAGSGKTRVLVHRIAWLMSVEQASPFSIMSVTFTNKAAAEMRgrieelmmgsasgmwngtfhgichrilrahyl 104
Cdd:cd17914 1 LSLIQGPPGTGKTRVLVKIVAALMQNKNGEPGRILLVTPTNKAAAQLD-------------------------------- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 105 daklpedfqiidsddqqrllkrlikaqnldekqwparqvswwingkkdeglrpnhidayhdpitqtylqlysayqeacdr 184
Cdd:cd17914 --------------------------------------------------------------------------------
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 185 aglvdfaeillrahellrdkkhirehyqarfkHILVDEFQDTNNIQYAWLRMMAGPDSHVMIVGDDDQSIYGWRGAKIEN 264
Cdd:cd17914 49 --------------------------------NILVDEAAQILEPETSRLIDLALDQGRVILVGDHDQLGPVWRGAVLAK 96
|
250 260
....*....|....*....|....*
gi 2327038875 265 -----IEKFTLEFPSVNTIRLEQNY 284
Cdd:cd17914 97 icneqSLFTRLVRLGVSLIRLQVQY 121
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
30-613 |
5.40e-19 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 91.96 E-value: 5.40e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 30 AGAGSGKTRVLVHR-IAWLMsvEQASPFSIMSVTFTNKAAAEMRGRI---------------------------EELMMG 81
Cdd:PRK13909 5 ASAGSGKTFALSVRfLALLF--KGANPSEILALTFTKKAANEMKERIidtllnlekekeeselneleeklglskEELLNK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 82 SASGMWN--------GTFHGICHRILRAHYLDAKLPEDFQI---------------IDSDDQQRLL-------------- 124
Cdd:PRK13909 83 RDKVYQEflnselkiSTIDAFFQKILRKFCLNLGLSPDFSIkedtkeelnekflsaLSKEELLELLafikqceskknnsf 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 125 ----------------------------------------------------KRLIKAQNLDE-----KQWPARQVSWW- 146
Cdd:PRK13909 163 felleklyeknnelklfekaknpiefdeekfleelrslkqqiqsietasknaKKAFKKEDFEEllnssKTWLEKESEYRy 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 147 ---INGKKDEGLR-------PNHIDAYHDPITQTYLQLYSAYQEACDRA----GLVDFAEILLRAHELLRDKKHIREHY- 211
Cdd:PRK13909 243 fkkLYNEELDAEFeelknalKRYYDAKENYKLSKLFKLLQLYKEAKNELnkkkNALDFDDISKKVYELLGEEEIDKDFLy 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 212 ---QARFKHILVDEFQDTNNIQYAWLR-----MMAG----PDSHVMIVGDDDQSIYGWRGAKIENIEKFTLEFpSVNTIR 279
Cdd:PRK13909 323 frlDSKISHILIDEFQDTSVLQYKILLplideIKSGegqkKFRSFFYVGDVKQSIYRFRGGKKELFDKVSKDF-KQKVDN 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 280 LEQNYRSTKTILEASNTLIANNTERMGKELWTDGKEGEPISVYSAYNELDE-ARFAVNKIKEWQDKGGVLNDAAML-YRN 357
Cdd:PRK13909 402 LDTNYRSAPLIVDFVNEVFKKKYKNYKTQYAEQHKSGGYVEVVEVADESEElLEQLLQEIQFLLEKGIDPDDIAILcWTN 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 358 NAQSRV---LEEALiqaGLPYRIYGGMRFFERQEIK---DALSYLrLMANRNDDAAFERVVNTPTRGLGD------KTLE 425
Cdd:PRK13909 482 DDALEIkefLQEQF---GIKAVTESSAKLINQPEVKaliEALKYC-LFGEEIYKHNVLKLLGKEPDKIPSflpkeeSVAE 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 426 TIRLAARERGctmwdaskaLLDEQVLpgrasgalsRFIELINaleddtdemslhsqtdhvikysglfamyeqekgekska 505
Cdd:PRK13909 558 FVKKLIEELK---------LYDENLL---------KFLELAS-------------------------------------- 581
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 506 RIENLEELVTATRQFEKPeeademsmltaflthAALEAGEGqadefedaVQLMTLHSAKGLEFP---------------- 569
Cdd:PRK13909 582 GYEDIEEFLFKLEPCDKE---------------IASEESKG--------VQIMTVHKSKGLEFEhvivcdrlgkpnsdss 638
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 570 -LVFMVGVEEGM---------------FPSQMSAEEAGRLEEERRLCYVGMTRAMQKLYI 613
Cdd:PRK13909 639 nLLFEYDGIELWqiyyrikgrenfdkdYARALEKEKALKYEEEINVLYVAFTRAKNSLIV 698
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
15-127 |
2.80e-16 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 76.10 E-value: 2.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 15 QREAV--AAPLENLLILAGAGSGKTRVLVHRIAWLMSVEQAsPFSIMSVTFTNKAAAEMRgrieELMMGSASgmwngTFH 92
Cdd:pfam13245 1 QREAVrtALPSKVVLLTGGPGTGKTTTIRHIVALLVALGGV-SFPILLAAPTGRAAKRLS----ERTGLPAS-----TIH 70
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2327038875 93 GIC--HRILRAHYL---DAKLPED------FQIIDSDDQQRLLKRL 127
Cdd:pfam13245 71 RLLgfDDLEAGGFLrdeEEPLDGDllivdeFSMVDLPLAYRLLKAL 116
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
15-346 |
3.52e-12 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 69.89 E-value: 3.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 15 QREAVAAPL-ENLLILAGAGSGKTRVLVHRIAWLM-----------------------------------SVEQASPFSI 58
Cdd:COG3973 196 QDRIIRADLrGVLVVQGGAGSGKTAVALHRAAYLLythrerlerggvlivgpnrlfldyisqvlpslgeeGVVQTTFGDL 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 59 MSVTFTN-------------KAAAEMRGRIEELmmgsasgmwngtfhgICHRILRAHYLDAKLPEDFQIIDSDD------ 119
Cdd:COG3973 276 VPELLGVeataeedpevarlKGSLRMAEVLDRA---------------VRDLEREVPFEDIRVEGGEVILSAEEiaeafy 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 120 ---------------QQRLLKRLIKAQNLDEKQWPARQVSWWING-KKDEGLRpNHIDAYHDPIT--QTYLQLYS--AYQ 179
Cdd:COG3973 341 rarrslphnkrrerlRERLLDALKDQLAAELGKLWDEERDELRRElRRSKPVR-AALNRLWPFLDpaELYRDLFSdpELL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 180 EACDRAGLVDFAEILLR--------------------AHELLRDKKHIREhyqarFKHILVDEFQDTNNIQYAWLrMMAG 239
Cdd:COG3973 420 ARAAGWLSPEERALLLRptrelkkgrwtvadvalldeLAELLGGPDRTWT-----YGHVVVDEAQDLSPMQWRVL-KRRF 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 240 PDSHVMIVGDDDQSIYGWRGAKIENIEKFTLEFPSVNTIRLEQNYRSTKTILEASNTLIAnntermgkELWTDGKE---- 315
Cdd:COG3973 494 PSASFTIVGDLAQAIHPYRGAESWEEVLEPLGGDRARLVELTKSYRSTAEIMEFANRVLR--------AAGPDLPPpesv 565
|
410 420 430
....*....|....*....|....*....|....
gi 2327038875 316 ---GEPISVYSAYNELDEARFAVNKIKEWQDKGG 346
Cdd:COG3973 566 rrhGEPPRVVRVPSEAELAAAVVEAVRELLAEGE 599
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
13-398 |
4.00e-11 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 66.01 E-value: 4.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 13 DKQREAVAAPL--ENLLILAGAGSGKTRVLVHRIAWLMSVEQASPFsimSVTFTNKA-AAEMRGRIEE-LMMGSASGMWN 88
Cdd:COG3972 161 DLQQERIARSIpdGPQRIRGVAGSGKTVLLAAKAAYLALKHPGWRI---LVTCFNRSlADHLRDLIPRfLRRFSNGEPED 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 89 ----GTFHGICHRILRAHyldaklpedfqiidsddqqrllkrlikaqnldekqwparqvswwiNGKKDEGLRPNhidayh 164
Cdd:COG3972 238 nvklIVFHAWGGKLLKQY---------------------------------------------GIPPLTFSQPN------ 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 165 dpitqtylqlySAYQEACDRAglvdFAEILLRAHEllrdkkhirehyqARFKHILVDEFQDTNNIQYaWL--RMMAGPDS 242
Cdd:COG3972 267 -----------EAFDEACKAL----LEAIQGEIIP-------------PIYDAILIDEAQDFEPEFL-RLlyQLLKPPKK 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 243 HVMIVGDDDQSIYGWRGAKIENIEKFTLEfpsvnTIRLEQNYRSTKTILEASNTL----------IANNTERMGKELWTD 312
Cdd:COG3972 318 RLIWAYDEAQNIYGRKIPSAGGIPAGIGR-----DTILKKNYRNTRPILTFAHAFgmgllrppglLQGDAEDYEVERPGD 392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 313 -----------GKEGEPISVYSAYNELDEARFAVNKIKEWQDKGGV-LNDAAMLYRNNAQSR----VLEEALIQAGLPYR 376
Cdd:COG3972 393 kvtlirppepaGRKGPLPEFKKYDDRAEELEAIAEEIKKNLRDEGLrPSDIAVIYLGNNEAKelgdRLAAALERQGIDSY 472
|
410 420
....*....|....*....|..
gi 2327038875 377 IYGGMRFFERQEIKDALSYLRL 398
Cdd:COG3972 473 IAGARSDPNFFWKDGGVTISTI 494
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
25-91 |
1.29e-10 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 57.91 E-value: 1.29e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2327038875 25 NLLILAGAGSGKTRVLVHRIAWLMSveqaSPFSIMSVTFTNKAAAEMRGRIEE--LMMGSASGMWNGTF 91
Cdd:cd17912 1 NILHLGPTGSGKTLVAIQKIASAMS----SGKSVLVVTPTKLLAHEILIVIDEiq*ILDPAAGWAWATR 65
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
552-622 |
2.44e-10 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 63.70 E-value: 2.44e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2327038875 552 EDAVQLMTLHSAKGLEFPLVFMVGVEEgmfpsqmsAEEAGRLEEERRLCYVGMTRAMQKLYITY--AEMRRLY 622
Cdd:COG3972 486 DGGVTISTIHRAKGLEAPVVIIVGLDQ--------LAKGESLERLRNLLYVAMTRARGWLVVSGsgESMAELY 550
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
544-614 |
5.93e-10 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 56.29 E-value: 5.93e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2327038875 544 GEGQADEFEDAVQLMTLHSAKGLEFPLVFMVGVEEGMfpsqmsaeeagrleEERRLCYVGMTRAMQKLYIT 614
Cdd:cd18786 32 GLSLDEFDLQLVGAITIDSSQGLTFDVVTLYLPTANS--------------LTPRRLYVALTRARKRLVIY 88
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
558-614 |
6.29e-08 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 49.49 E-value: 6.29e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2327038875 558 MTLHSAKGLEFPLVFMVGVEEGmfpsqmsaeEAGRLEEERRLCYVGMTRAMQKLYIT 614
Cdd:pfam13538 5 LTVHKAQGSEFPAVFLVDPDLT---------AHYHSMLRRRLLYTAVTRARKKLVLV 52
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
207-297 |
7.62e-07 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 52.67 E-value: 7.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327038875 207 IREhyqaRFKHILVDEFQDTNNIQYAWLRMMAG--PDSHVMIVGDDDQSIYGWRGAKIeniekFTL-----EFPSVNTir 279
Cdd:PRK10876 374 IRT----RYPVAMIDEFQDTDPQQYRIFRRIYRhqPETALLLIGDPKQAIYAFRGADI-----FTYmkarsEVSAHYT-- 442
|
90
....*....|....*...
gi 2327038875 280 LEQNYRSTKTILEASNTL 297
Cdd:PRK10876 443 LDTNWRSAPGMVNSVNKL 460
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
11-72 |
4.80e-04 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 43.43 E-value: 4.80e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2327038875 11 LNDKQREAV--AAPLENLLILAG-AGSGKTRvLVHRIAWLMsveQASPFSIMSVTFTNKAAAEMR 72
Cdd:COG0507 125 LSDEQREAValALTTRRVSVLTGgAGTGKTT-TLRALLAAL---EALGLRVALAAPTGKAAKRLS 185
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
558-613 |
1.66e-03 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 37.93 E-value: 1.66e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2327038875 558 MTLHSAKGLEFPLVFMVGVEEGMFpsqmsaeeagrleEERRLCYVGMTRAMQKLYI 613
Cdd:cd18809 36 MTIHKSQGSEFDRVIVVLPTSHPM-------------LSRGLLYTALTRARKLLTL 78
|
|
| |
