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Conserved domains on  [gi|2327962477|ref|WP_265147813|]
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sigma-54-dependent Fis family transcriptional regulator [Rhodococcus opacus]

Protein Classification

sigma-54-dependent Fis family transcriptional regulator( domain architecture ID 11461735)

sigma-54-dependent Fis family transcriptional regulator similar to the acetoin dehydrogenase operon transcriptional activator AcoR, a transcriptional activator of the acoABCL operon that encodes the acetoin dehydrogenase complex

Gene Ontology:  GO:0005524|GO:0043565|GO:0000160|GO:0006355
PubMed:  8830233|11274109|32088504

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AcoR COG3284
Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];
3-521 9.36e-71

Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];


:

Pssm-ID: 442514 [Multi-domain]  Cd Length: 625  Bit Score: 237.88  E-value: 9.36e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477   3 LRQVAGEIVEHRRAALSQSSCSLAMTDSSGRLLRRWVeDRGFASILDSQCIAPDYTWGEAAVGTNSSGIVLETGRSATVA 82
Cdd:COG3284    66 LLRAARPVLERLYEQLAGSGSVVLLTDADGVILDTLG-DPRFLDRARRVGLAPGADWSEEARGTNAIGTALAEGRPVTVH 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477  83 GPEHFSEELLDFTCAGAPIRHPiTRRLVGTLNVTVRFRDTSPILQTWVTDLALEIERALLNVASRREQVLMSAYLAENRD 162
Cdd:COG3284   145 GAEHFLEANHGLTCSAAPIFDP-DGRLLGVLDISGPARSSQPHTLALVRAAARRIENRLFLRSFRREWRLRLHFLPEFLG 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 163 -IRHPVICLDDQTVI--SNAAAARRFSSVDQALLWEHASTVLHSSAphDSTVSLGDGTPAVVKVSKVFDGtRPVGAVLRV 239
Cdd:COG3284   224 sLSEGLLAFDEDGRIvaANRAARRLLGLADAALLGRPLEELFGLDL--EALPDGARRAPASPRPLRLRDG-RRLGALLRL 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 240 MPDSTCAASLLPKGYGAEPIRGLVGTSDAWRKLCHEAAELGQR--PKLLVGDAGVGKFAVASAL--AGSRA----VVVEA 311
Cdd:COG3284   301 RPARRAARAAPAGAPAPAALAALAGGDPAMRRALRRARRLADRdiPVLILGETGTGKELFARAIhaASPRAdgpfVAVNC 380

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 312 ESLSNESFEHWL--------DNVRRmvsGGAPKLILRR------LDRVNDDEAHALIRLLD-----EFTRNG----IQVD 368
Cdd:COG3284   381 AAIPEELIESELfgyepgafTGARR---KGRPGKIEQAdggtlfLDEIGDMPLALQARLLRvlqerEVTPLGgtkpIPVD 457

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 369 -----ATMRQVSPHEDRSPIAEwfD-------VVLEVPSLSQRiQDLPLILDALTMRHLPAARSVRWLPNAVQTLSRIHW 436
Cdd:COG3284   458 vrliaATHRDLRELVAAGRFRE--DlyyrlngLTLTLPPLRER-EDLPALIEHLLRELAAGRGPLRLSPEALALLAAYPW 534

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 437 NRNVASIDAVVREILARHRHPTISAADLPPRLRAE------AGRRDLAGLEHVEAKAILDALQKARGNKRIAADDLGIAR 510
Cdd:COG3284   535 PGNVRELRNVLRTALALADGGVITVEDLPDELRAElaaaapAAAAPLTSLEEAERDAILRALRACGGNVSAAARALGISR 614

                         570
                  ....*....|.
gi 2327962477 511 STLYRKVRALG 521
Cdd:COG3284   615 STLYRKLKRYG 625
 
Name Accession Description Interval E-value
AcoR COG3284
Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];
3-521 9.36e-71

Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];


Pssm-ID: 442514 [Multi-domain]  Cd Length: 625  Bit Score: 237.88  E-value: 9.36e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477   3 LRQVAGEIVEHRRAALSQSSCSLAMTDSSGRLLRRWVeDRGFASILDSQCIAPDYTWGEAAVGTNSSGIVLETGRSATVA 82
Cdd:COG3284    66 LLRAARPVLERLYEQLAGSGSVVLLTDADGVILDTLG-DPRFLDRARRVGLAPGADWSEEARGTNAIGTALAEGRPVTVH 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477  83 GPEHFSEELLDFTCAGAPIRHPiTRRLVGTLNVTVRFRDTSPILQTWVTDLALEIERALLNVASRREQVLMSAYLAENRD 162
Cdd:COG3284   145 GAEHFLEANHGLTCSAAPIFDP-DGRLLGVLDISGPARSSQPHTLALVRAAARRIENRLFLRSFRREWRLRLHFLPEFLG 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 163 -IRHPVICLDDQTVI--SNAAAARRFSSVDQALLWEHASTVLHSSAphDSTVSLGDGTPAVVKVSKVFDGtRPVGAVLRV 239
Cdd:COG3284   224 sLSEGLLAFDEDGRIvaANRAARRLLGLADAALLGRPLEELFGLDL--EALPDGARRAPASPRPLRLRDG-RRLGALLRL 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 240 MPDSTCAASLLPKGYGAEPIRGLVGTSDAWRKLCHEAAELGQR--PKLLVGDAGVGKFAVASAL--AGSRA----VVVEA 311
Cdd:COG3284   301 RPARRAARAAPAGAPAPAALAALAGGDPAMRRALRRARRLADRdiPVLILGETGTGKELFARAIhaASPRAdgpfVAVNC 380

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 312 ESLSNESFEHWL--------DNVRRmvsGGAPKLILRR------LDRVNDDEAHALIRLLD-----EFTRNG----IQVD 368
Cdd:COG3284   381 AAIPEELIESELfgyepgafTGARR---KGRPGKIEQAdggtlfLDEIGDMPLALQARLLRvlqerEVTPLGgtkpIPVD 457

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 369 -----ATMRQVSPHEDRSPIAEwfD-------VVLEVPSLSQRiQDLPLILDALTMRHLPAARSVRWLPNAVQTLSRIHW 436
Cdd:COG3284   458 vrliaATHRDLRELVAAGRFRE--DlyyrlngLTLTLPPLRER-EDLPALIEHLLRELAAGRGPLRLSPEALALLAAYPW 534

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 437 NRNVASIDAVVREILARHRHPTISAADLPPRLRAE------AGRRDLAGLEHVEAKAILDALQKARGNKRIAADDLGIAR 510
Cdd:COG3284   535 PGNVRELRNVLRTALALADGGVITVEDLPDELRAElaaaapAAAAPLTSLEEAERDAILRALRACGGNVSAAARALGISR 614

                         570
                  ....*....|.
gi 2327962477 511 STLYRKVRALG 521
Cdd:COG3284   615 STLYRKLKRYG 625
PRK11388 PRK11388
DNA-binding transcriptional regulator DhaR; Provisional
 18-529 9.24e-20

DNA-binding transcriptional regulator DhaR; Provisional


Pssm-ID: 183114 [Multi-domain]  Cd Length: 638  Bit Score: 92.82  E-value: 9.24e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477  18 LSQSSCSLAMTDSSGRLLRRwVEDRGFASILDSQCIAPDYTWGEAAVGTNSSGIVLETGRSATVAGPEHFSEELLDFTCA 97
Cdd:PRK11388   68 MADRECALLILDETGCILSR-NGDPQTLQQLSALGFNDGTYCAEGIIGTNALSLAAISGQPVKTMGDQHFKQALHNWAFC 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477  98 GAPIrHPITRRLVGTLNVTVRFRDTSpilqtwVTDLALeierallNVASRRE---QVLMSAYLAENRdiRH--------- 165
Cdd:PRK11388  147 ATPV-FDSKGRLTGTIALACPVEQTS------AADLPL-------TLSIAREvgnLLLTDSLLAESN--RHlnqlnalle 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 166 ----PVICLDDQTVIS--NAAAARRFSSVDQALLWEHASTV------LHSSAPHDSTVSLGDGT--------PAVVKVSK 225
Cdd:PRK11388  211 smddGVIAWDEQGNLQflNAQAARLLRLDATASQGRAITELltlpavLQQAIKQAHPLKHVEVTfesqgqfiDAVITLKP 290

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 226 VFDGTR--------PVGAVLRVMPDSTCAASLlpkgygaePIRGLVGTSDAWRKLCHEA--AELGQRPKLLVGDAGVGKF 295
Cdd:PRK11388  291 IIEGQGtsfilllhPVEQMRQLMTSQLGKVSH--------TFDHMPQDSPQMRRLIHFGrqAAKSSFPVLLCGEEGVGKA 362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 296 AVASAL------AGSRAVVVEAESLSNESFEHWL------DNVRRMVS------GGApkLILRRLDRVNDDEAHALIRLL 357
Cdd:PRK11388  363 LLAQAIhneserAAGPYIAVNCQLYPDEALAEEFlgsdrtDSENGRLSkfelahGGT--LFLEKVEYLSPELQSALLQVL 440

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 358 DE--FTR----NGIQVD--------ATMRQ--VSPHEDRSPIAEWFDVVLEVPSLSQRIQDLPLILDALtMRHLPAARSV 421
Cdd:PRK11388  441 KTgvITRldsrRLIPVDvrviatttADLAMlvEQNRFSRQLYYALHAFEITIPPLRMRREDIPALVNNK-LRSLEKRFST 519

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 422 RWL--PNAVQTLSRIHWNRNVASIDAVVREILARHRHPTISAADLPPRLRAEAGRRDLAG--------LEHVEAKAILDA 491
Cdd:PRK11388  520 RLKidDDALARLVSYRWPGNDFELRSVIENLALSSDNGRIRLSDLPEHLFTEQATDDVSAtrlstslsLAELEKEAIINA 599

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 2327962477 492 LQKARGNKRIAADDLGIARSTLYRKVRALGIDLSSSNY 529
Cdd:PRK11388  600 AQVCGGRIQEMAALLGIGRTTLWRKMKQHGIDAGQFKR 637
HTH_8 pfam02954
Bacterial regulatory protein, Fis family;
480-519 2.17e-07

Bacterial regulatory protein, Fis family;


Pssm-ID: 427077 [Multi-domain]  Cd Length: 40  Bit Score: 47.00  E-value: 2.17e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2327962477 480 LEHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRA 519
Cdd:pfam02954   1 LEEVEKELIEAALERTGGNKSKAARLLGISRRTLYRKLKK 40
PEP_resp_reg TIGR02915
PEP-CTERM-box response regulator transcription factor; Members of this protein family share ...
 388-522 1.56e-04

PEP-CTERM-box response regulator transcription factor; Members of this protein family share full-length homology with (but do not include) the acetoacetate metabolism regulatory protein AtoC (see SP|Q06065). These proteins have a Fis family DNA binding sequence (pfam02954), a response regulator receiver domain (pfam00072), and sigma-54 interaction domain (pfam00158). [Regulatory functions, DNA interactions]


Pssm-ID: 274348 [Multi-domain]  Cd Length: 445  Bit Score: 44.35  E-value: 1.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 388 DVVLEVPSLSQRIQDLPLILDALTMRH-LPAARSVRWLP-NAVQTLSRIHWNRNVASIDAVVREILARHRHPTISAADLP 465
Cdd:TIGR02915 304 EISITIPPLRSRDGDAVLLANAFLERFaRELKRKTKGFTdDALRALEAHAWPGNVRELENKVKRAVIMAEGNQITAEDLG 383

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2327962477 466 PRLRAEAGRRDLAGL----EHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRALGI 522
Cdd:TIGR02915 384 LDARERAETPLEVNLrevrERAEREAVRKAIARVDGNIARAAELLGITRPTLYDLMKKHGI 444
CE4_u9 cd10933
Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase ...
 446-528 8.09e-03

Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; This family corresponds to a group of uncharacterized bacterial proteins with high sequence similarity to the catalytic domain of the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily.


Pssm-ID: 200559 [Multi-domain]  Cd Length: 266  Bit Score: 38.44  E-value: 8.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 446 VVREILAR------HRHPTISAADLPPRLRAEAGRRDLAGLEHVEAKAIL----DALQKARGNKRIA--ADDLGIARSTL 513
Cdd:cd10933    75 IVRLIVARghdvqlHLHPEWLDEARPLLPGGDRNRRHMHDYSLEEQTQLIeegrDLLKRAGAPDPIAfrAGGFGANDDTL 154

                          90
                  ....*....|....*
gi 2327962477 514 yRKVRALGIDLSSSN 528
Cdd:cd10933   155 -RALAANGIRIDSSY 168
 
Name Accession Description Interval E-value
AcoR COG3284
Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];
3-521 9.36e-71

Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];


Pssm-ID: 442514 [Multi-domain]  Cd Length: 625  Bit Score: 237.88  E-value: 9.36e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477   3 LRQVAGEIVEHRRAALSQSSCSLAMTDSSGRLLRRWVeDRGFASILDSQCIAPDYTWGEAAVGTNSSGIVLETGRSATVA 82
Cdd:COG3284    66 LLRAARPVLERLYEQLAGSGSVVLLTDADGVILDTLG-DPRFLDRARRVGLAPGADWSEEARGTNAIGTALAEGRPVTVH 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477  83 GPEHFSEELLDFTCAGAPIRHPiTRRLVGTLNVTVRFRDTSPILQTWVTDLALEIERALLNVASRREQVLMSAYLAENRD 162
Cdd:COG3284   145 GAEHFLEANHGLTCSAAPIFDP-DGRLLGVLDISGPARSSQPHTLALVRAAARRIENRLFLRSFRREWRLRLHFLPEFLG 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 163 -IRHPVICLDDQTVI--SNAAAARRFSSVDQALLWEHASTVLHSSAphDSTVSLGDGTPAVVKVSKVFDGtRPVGAVLRV 239
Cdd:COG3284   224 sLSEGLLAFDEDGRIvaANRAARRLLGLADAALLGRPLEELFGLDL--EALPDGARRAPASPRPLRLRDG-RRLGALLRL 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 240 MPDSTCAASLLPKGYGAEPIRGLVGTSDAWRKLCHEAAELGQR--PKLLVGDAGVGKFAVASAL--AGSRA----VVVEA 311
Cdd:COG3284   301 RPARRAARAAPAGAPAPAALAALAGGDPAMRRALRRARRLADRdiPVLILGETGTGKELFARAIhaASPRAdgpfVAVNC 380

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 312 ESLSNESFEHWL--------DNVRRmvsGGAPKLILRR------LDRVNDDEAHALIRLLD-----EFTRNG----IQVD 368
Cdd:COG3284   381 AAIPEELIESELfgyepgafTGARR---KGRPGKIEQAdggtlfLDEIGDMPLALQARLLRvlqerEVTPLGgtkpIPVD 457

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 369 -----ATMRQVSPHEDRSPIAEwfD-------VVLEVPSLSQRiQDLPLILDALTMRHLPAARSVRWLPNAVQTLSRIHW 436
Cdd:COG3284   458 vrliaATHRDLRELVAAGRFRE--DlyyrlngLTLTLPPLRER-EDLPALIEHLLRELAAGRGPLRLSPEALALLAAYPW 534

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 437 NRNVASIDAVVREILARHRHPTISAADLPPRLRAE------AGRRDLAGLEHVEAKAILDALQKARGNKRIAADDLGIAR 510
Cdd:COG3284   535 PGNVRELRNVLRTALALADGGVITVEDLPDELRAElaaaapAAAAPLTSLEEAERDAILRALRACGGNVSAAARALGISR 614

                         570
                  ....*....|.
gi 2327962477 511 STLYRKVRALG 521
Cdd:COG3284   615 STLYRKLKRYG 625
PRK11388 PRK11388
DNA-binding transcriptional regulator DhaR; Provisional
 18-529 9.24e-20

DNA-binding transcriptional regulator DhaR; Provisional


Pssm-ID: 183114 [Multi-domain]  Cd Length: 638  Bit Score: 92.82  E-value: 9.24e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477  18 LSQSSCSLAMTDSSGRLLRRwVEDRGFASILDSQCIAPDYTWGEAAVGTNSSGIVLETGRSATVAGPEHFSEELLDFTCA 97
Cdd:PRK11388   68 MADRECALLILDETGCILSR-NGDPQTLQQLSALGFNDGTYCAEGIIGTNALSLAAISGQPVKTMGDQHFKQALHNWAFC 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477  98 GAPIrHPITRRLVGTLNVTVRFRDTSpilqtwVTDLALeierallNVASRRE---QVLMSAYLAENRdiRH--------- 165
Cdd:PRK11388  147 ATPV-FDSKGRLTGTIALACPVEQTS------AADLPL-------TLSIAREvgnLLLTDSLLAESN--RHlnqlnalle 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 166 ----PVICLDDQTVIS--NAAAARRFSSVDQALLWEHASTV------LHSSAPHDSTVSLGDGT--------PAVVKVSK 225
Cdd:PRK11388  211 smddGVIAWDEQGNLQflNAQAARLLRLDATASQGRAITELltlpavLQQAIKQAHPLKHVEVTfesqgqfiDAVITLKP 290

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 226 VFDGTR--------PVGAVLRVMPDSTCAASLlpkgygaePIRGLVGTSDAWRKLCHEA--AELGQRPKLLVGDAGVGKF 295
Cdd:PRK11388  291 IIEGQGtsfilllhPVEQMRQLMTSQLGKVSH--------TFDHMPQDSPQMRRLIHFGrqAAKSSFPVLLCGEEGVGKA 362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 296 AVASAL------AGSRAVVVEAESLSNESFEHWL------DNVRRMVS------GGApkLILRRLDRVNDDEAHALIRLL 357
Cdd:PRK11388  363 LLAQAIhneserAAGPYIAVNCQLYPDEALAEEFlgsdrtDSENGRLSkfelahGGT--LFLEKVEYLSPELQSALLQVL 440

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 358 DE--FTR----NGIQVD--------ATMRQ--VSPHEDRSPIAEWFDVVLEVPSLSQRIQDLPLILDALtMRHLPAARSV 421
Cdd:PRK11388  441 KTgvITRldsrRLIPVDvrviatttADLAMlvEQNRFSRQLYYALHAFEITIPPLRMRREDIPALVNNK-LRSLEKRFST 519

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 422 RWL--PNAVQTLSRIHWNRNVASIDAVVREILARHRHPTISAADLPPRLRAEAGRRDLAG--------LEHVEAKAILDA 491
Cdd:PRK11388  520 RLKidDDALARLVSYRWPGNDFELRSVIENLALSSDNGRIRLSDLPEHLFTEQATDDVSAtrlstslsLAELEKEAIINA 599

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 2327962477 492 LQKARGNKRIAADDLGIARSTLYRKVRALGIDLSSSNY 529
Cdd:PRK11388  600 AQVCGGRIQEMAALLGIGRTTLWRKMKQHGIDAGQFKR 637
AtoC COG2204
DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, ...
 256-521 2.27e-17

DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains [Signal transduction mechanisms];


Pssm-ID: 441806 [Multi-domain]  Cd Length: 418  Bit Score: 84.24  E-value: 2.27e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 256 AEPIRGLVGTSDAWRKLCHEAAELGQR--PKLLVGDAGVGKFAVASAL--AGSRA----VVVEAESLSNESFEHWLDNVR 327
Cdd:COG2204   127 NAEDSGLIGRSPAMQEVRRLIEKVAPSdaTVLITGESGTGKELVARAIhrLSPRAdgpfVAVNCAAIPEELLESELFGHE 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 328 RMVSGGAPKLILRR----------LDRVNDDEAHALIRLL-----DEFTRNG----IQVD-----ATMR----QVSPHED 379
Cdd:COG2204   207 KGAFTGAVARRIGKfeladggtlfLDEIGEMPLALQAKLLrvlqeREFERVGgnkpIPVDvrviaATNRdleeLVEEGRF 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 380 RSPIAEWFDVV-LEVPSLSQRIQDLPLILDALTMRHLPAA-RSVRWLPNAVQTLSRIHWNRNVASIDAVVREILARHRHP 457
Cdd:COG2204   287 REDLYYRLNVFpIELPPLRERREDIPLLARHFLARFAAELgKPVKLSPEALEALLAYDWPGNVRELENVIERAVILADGE 366

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2327962477 458 TISAADLPPRLraeagrrdlaglEHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRALG 521
Cdd:COG2204   367 VITAEDLPEAL------------EEVERELIERALEETGGNVSRAAELLGISRRTLYRKLKKYG 418
RocR COG3829
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis ...
 389-523 4.68e-17

RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];


Pssm-ID: 443041 [Multi-domain]  Cd Length: 448  Bit Score: 83.67  E-value: 4.68e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 389 VVLEVPSLSQRIQDLPLILDALtMRHLPAA---RSVRWLPNAVQTLSRIHW--NrnvasidavVRE---ILAR----HRH 456
Cdd:COG3829   305 IPIHIPPLRERKEDIPLLAEHF-LEKFNKKygkNIKGISPEALELLLAYDWpgN---------VRElenVIERavvlSEG 374

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2327962477 457 PTISAADLPPRLRAEAGRRDLAG-------LEHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRALGID 523
Cdd:COG3829   375 DVITPEHLPEYLLEEAEAASAAEegslkeaLEEVEKELIEEALEKTGGNKSKAAKALGISRSTLYRKLKKYGIK 448
PRK10365 PRK10365
sigma-54-dependent response regulator transcription factor ZraR;
261-517 1.98e-14

sigma-54-dependent response regulator transcription factor ZraR;


Pssm-ID: 182412 [Multi-domain]  Cd Length: 441  Bit Score: 75.45  E-value: 1.98e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 261 GLVGTSDAWRKLCHEAAELGQRPK--LLVGDAGVGKFAVASALAGSRA------VVVEAESLSNESFEHWLDNVRRMVSG 332
Cdd:PRK10365  140 GMVGKSPAMQHLLSEIALVAPSEAtvLIHGDSGTGKELVARAIHASSArsekplVTLNCAALNESLLESELFGHEKGAFT 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 333 GAPKlilRR-------------LDRVNDDEAHALIRLLD-----EFTRNG----IQVD-----ATMR----QVSPHEDRS 381
Cdd:PRK10365  220 GADK---RRegrfveadggtlfLDEIGDISPMMQVRLLRaiqerEVQRVGsnqtISVDvrliaATHRdlaaEVNAGRFRQ 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 382 PIAEWFDVV-LEVPSLSQRIQDLPLILDALTMRHlpAARSVR----WLPNAVQTLSRIHWNRNVASIDAVVREILARHRH 456
Cdd:PRK10365  297 DLYYRLNVVaIEVPSLRQRREDIPLLAGHFLQRF--AERNRKavkgFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTG 374

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2327962477 457 PTISAADLPPRLRAE----AGRRDLAGLEHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKV 517
Cdd:PRK10365  375 EYISERELPLAIASTpiplGQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKL 439
FhlA COG3604
FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis ...
 391-523 1.61e-12

FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];


Pssm-ID: 442823 [Multi-domain]  Cd Length: 338  Bit Score: 68.72  E-value: 1.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 391 LEVPSLSQRIQDLPLILDALTMRHLPA--ARSVRWLPNAVQTLSRIHWNRNVASIDAVVREILARHRHPTISAADLPPRL 468
Cdd:COG3604   212 IRLPPLRERREDIPLLAEHFLEKFSRRlgKPILRLSPEALEALMAYPWPGNVRELENVIERAVILAEGGVLDADDLAPGS 291

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2327962477 469 RAEagrrdlagLEHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRALGID 523
Cdd:COG3604   292 REA--------LEEVEREHILEALERTGGNIAGAARLLGLTPSTLRSRMKKLGIK 338
PRK15424 PRK15424
propionate catabolism operon regulatory protein PrpR; Provisional
 391-519 4.01e-08

propionate catabolism operon regulatory protein PrpR; Provisional


Pssm-ID: 237963 [Multi-domain]  Cd Length: 538  Bit Score: 55.88  E-value: 4.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 391 LEVPSLSQRIQDLPLILDALtMRHLPAARSVRWLPNAVQTLS-------RIHWNRNVASIDAVVREI---LARHRHPTIS 460
Cdd:PRK15424  396 LQLPPLRERVADILPLAESF-LKQSLAALSAPFSAALRQGLQqcetlllHYDWPGNVRELRNLMERLalfLSVEPTPDLT 474

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2327962477 461 AADLppRLRAEAGRRDLAGLEH--VEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRA 519
Cdd:PRK15424  475 PQFL--QLLLPELARESAKTPAprLLAATLQQALERFNGDKTAAANYLGISRTTLWRRLKA 533
HTH_8 pfam02954
Bacterial regulatory protein, Fis family;
480-519 2.17e-07

Bacterial regulatory protein, Fis family;


Pssm-ID: 427077 [Multi-domain]  Cd Length: 40  Bit Score: 47.00  E-value: 2.17e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2327962477 480 LEHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRA 519
Cdd:pfam02954   1 LEEVEKELIEAALERTGGNKSKAARLLGISRRTLYRKLKK 40
PRK11361 PRK11361
acetoacetate metabolism transcriptional regulator AtoC;
389-523 8.66e-07

acetoacetate metabolism transcriptional regulator AtoC;


Pssm-ID: 183099 [Multi-domain]  Cd Length: 457  Bit Score: 51.39  E-value: 8.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 389 VVLEVPSLSQRIQDLPLILDALTMRHlpAARSVRWL----PNAVQTLSRIHWNRNVASIDAVVREILARHRHPTISAADL 464
Cdd:PRK11361  309 IHLILPPLRDRREDISLLANHFLQKF--SSENQRDIididPMAMSLLTAWSWPGNIRELSNVIERAVVMNSGPIIFSEDL 386

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2327962477 465 PPRLRAEA-----------GRRDLAGL-EHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRALGID 523
Cdd:PRK11361  387 PPQIRQPVcnagevktapvGERNLKEEiKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYKLQEYGID 457
pspF PRK11608
phage shock protein operon transcriptional activator; Provisional
 387-520 8.74e-06

phage shock protein operon transcriptional activator; Provisional


Pssm-ID: 236936 [Multi-domain]  Cd Length: 326  Bit Score: 47.74  E-value: 8.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 387 FDVVlEVPSLSQRIQDLPLILD--ALTM-RHLPAARSVRWLPNAVQTLSRIHWNRNVASIDAVVREILARH--------- 454
Cdd:PRK11608  171 FDVV-QLPPLRERQSDIMLMAEhfAIQMcRELGLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHgtseypldn 249

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2327962477 455 -------RHPTISAADLPPRLRAEAGRRDLAGLEHVEAKAILD-ALQKARGNKRIAADDLGIArstlYRKVRAL 520
Cdd:PRK11608  250 iiidpfkRRPAEEAIAVSETTSLPTLPLDLREWQHQQEKELLQrSLQQAKFNQKRAAELLGLT----YHQLRAL 319
PRK15429 PRK15429
formate hydrogenlyase transcriptional activator FlhA;
342-523 2.31e-05

formate hydrogenlyase transcriptional activator FlhA;


Pssm-ID: 237965 [Multi-domain]  Cd Length: 686  Bit Score: 47.13  E-value: 2.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 342 LDRVND---DEAHALIRLLDE--FTRNG----IQVD-----ATMRQ----VSPHEDRSPIAEWFDVV-LEVPSLSQRIQD 402
Cdd:PRK15429  476 LDEVGDmplELQPKLLRVLQEqeFERLGsnkiIQTDvrliaATNRDlkkmVADREFRSDLYYRLNVFpIHLPPLRERPED 555

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 403 LPLILDALTM---RHLpaARSVRWLP-NAVQTLSRIHWNRNVASIDAVVRE--ILARHRHPTISAADL-PPRLRAEAGRR 475
Cdd:PRK15429  556 IPLLVKAFTFkiaRRM--GRNIDSIPaETLRTLSNMEWPGNVRELENVIERavLLTRGNVLQLSLPDItLPEPETPPAAT 633

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2327962477 476 DLAGLEHVEAKAILDALQKARG---NKRIAADDLGIARSTLYRKVRALGID 523
Cdd:PRK15429  634 VVAQEGEDEYQLIVRVLKETNGvvaGPKGAAQRLGLKRTTLLSRMKRLGID 684
Fis COG2901
DNA-binding protein Fis (factor for inversion stimulation) [Transcription];
480-523 3.48e-05

DNA-binding protein Fis (factor for inversion stimulation) [Transcription];


Pssm-ID: 442146 [Multi-domain]  Cd Length: 83  Bit Score: 42.11  E-value: 3.48e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2327962477 480 LEHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRALGID 523
Cdd:COG2901    40 LAEVEKPLLETVLEHTRGNQSRAAEMLGINRNTLRKKLKQYGLL 83
PEP_resp_reg TIGR02915
PEP-CTERM-box response regulator transcription factor; Members of this protein family share ...
 388-522 1.56e-04

PEP-CTERM-box response regulator transcription factor; Members of this protein family share full-length homology with (but do not include) the acetoacetate metabolism regulatory protein AtoC (see SP|Q06065). These proteins have a Fis family DNA binding sequence (pfam02954), a response regulator receiver domain (pfam00072), and sigma-54 interaction domain (pfam00158). [Regulatory functions, DNA interactions]


Pssm-ID: 274348 [Multi-domain]  Cd Length: 445  Bit Score: 44.35  E-value: 1.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 388 DVVLEVPSLSQRIQDLPLILDALTMRH-LPAARSVRWLP-NAVQTLSRIHWNRNVASIDAVVREILARHRHPTISAADLP 465
Cdd:TIGR02915 304 EISITIPPLRSRDGDAVLLANAFLERFaRELKRKTKGFTdDALRALEAHAWPGNVRELENKVKRAVIMAEGNQITAEDLG 383

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2327962477 466 PRLRAEAGRRDLAGL----EHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVRALGI 522
Cdd:TIGR02915 384 LDARERAETPLEVNLrevrERAEREAVRKAIARVDGNIARAAELLGITRPTLYDLMKKHGI 444
glnG PRK10923
nitrogen regulation protein NR(I); Provisional
 391-523 1.76e-03

nitrogen regulation protein NR(I); Provisional


Pssm-ID: 182842 [Multi-domain]  Cd Length: 469  Bit Score: 41.01  E-value: 1.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 391 LEVPSLSQRIQDLPLILDAL---TMRHLPAARSVrWLPNAVQTLSRIHWNRNVASIDAVVREILARHRHPTISAADLPPR 467
Cdd:PRK10923  306 VHLPPLRERREDIPRLARHFlqvAARELGVEAKL-LHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGE 384

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 468 LRA---------------------------EAGRRDL--AGLEHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVR 518
Cdd:PRK10923  385 LFEstvpestsqmqpdswatllaqwadralRSGHQNLlsEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLK 464


                  ....*
gi 2327962477 519 ALGID 523
Cdd:PRK10923  465 ELGME 469
PRK05022 PRK05022
nitric oxide reductase transcriptional regulator NorR;
391-522 2.22e-03

nitric oxide reductase transcriptional regulator NorR;


Pssm-ID: 235331 [Multi-domain]  Cd Length: 509  Bit Score: 40.54  E-value: 2.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 391 LEVPSLSQRIQDLPL----ILDALtmRHLPAARSVRWLPNAVQTLSRIHWNRNVasidavvRE---------ILARHRHP 457
Cdd:PRK05022  355 LSVPPLRERGDDVLLlagyFLEQN--RARLGLRSLRLSPAAQAALLAYDWPGNV-------RElehvisraaLLARARGA 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 458 ----TISAADL---------------PPRLRAEAGRRDLagLEHVEAKAILDALQKARGNKRIAADDLGIARSTLYRKVR 518
Cdd:PRK05022  426 grivTLEAQHLdlpaevalpppeaaaAPAAVVSQNLREA--TEAFQRQLIRQALAQHQGNWAAAARALELDRANLHRLAK 503


                  ....
gi 2327962477 519 ALGI 522
Cdd:PRK05022  504 RLGL 507
PRK15115 PRK15115
response regulator GlrR; Provisional
 389-515 4.82e-03

response regulator GlrR; Provisional


Pssm-ID: 185070 [Multi-domain]  Cd Length: 444  Bit Score: 39.44  E-value: 4.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 389 VVLEVPSLSQRIQDLPLILDAL----TMRHLPAARSvrWLPNAVQTLSRIHWNRNVASIDAVVREILARHRHPTISAADL 464
Cdd:PRK15115  300 VSLKIPALAERTEDIPLLANHLlrqaAERHKPFVRA--FSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALV 377

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2327962477 465 PPRLRAEagrrDLAGLEHVEAKA------ILDALQKARGNKRIAADDLGIARSTLYR 515
Cdd:PRK15115  378 EQALEGE----NTALPTFVEARNqfelnyLRKLLQITKGNVTHAARMAGRNRTEFYK 430
CE4_u9 cd10933
Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase ...
 446-528 8.09e-03

Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; This family corresponds to a group of uncharacterized bacterial proteins with high sequence similarity to the catalytic domain of the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily.


Pssm-ID: 200559 [Multi-domain]  Cd Length: 266  Bit Score: 38.44  E-value: 8.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2327962477 446 VVREILAR------HRHPTISAADLPPRLRAEAGRRDLAGLEHVEAKAIL----DALQKARGNKRIA--ADDLGIARSTL 513
Cdd:cd10933    75 IVRLIVARghdvqlHLHPEWLDEARPLLPGGDRNRRHMHDYSLEEQTQLIeegrDLLKRAGAPDPIAfrAGGFGANDDTL 154

                          90
                  ....*....|....*
gi 2327962477 514 yRKVRALGIDLSSSN 528
Cdd:cd10933   155 -RALAANGIRIDSSY 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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