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Conserved domains on  [gi|2329596546|ref|WP_265589603|]
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amidase family protein, partial [Enterobacter sp. C6]

Protein Classification

amidase( domain architecture ID 139642)

amidase catalyzes the hydrolysis of an amide

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Amidase super family cl18951
Amidase;
1-229 3.00e-119

Amidase;


The actual alignment was detected with superfamily member PRK09201:

Pssm-ID: 450241 [Multi-domain]  Cd Length: 465  Bit Score: 347.34  E-value: 3.00e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546   1 TSDGFQAESSREQTRPLLDRGLDGLRCAVLGGYFTTWCDTDARDAVARVAKALDVQDELQFPDAELARSAAFIISASEGG 80
Cdd:PRK09201  237 PQDPFQADRPAEPTAPLLDRGAEGLRIAVLGGYFAQWADPEARAAVDRVAKALGATREVELPEAARARAAAFIITASEGG 316
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  81 NQYLPALRREPERFEPHSRERLLAGAMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATLAGEQTMEINGQL 160
Cdd:PRK09201  317 NLHLPALRTRPQDFDPASRDRLLAGAMLPAAWYVQAQRFRRWFRQAVLELFEHVDVLIAPATPCSAPLIGQETMRIDGVE 396
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2329596546 161 LPIRASMGMLTQPISFLGLPVTTVPLRTAQGAPIGLQLIAAPFNEQACLRVARVLEESGITDARPAEIA 229
Cdd:PRK09201  397 LPVRANLGILTQPISFIGLPVVAVPLRTPGGLPIGVQLIAAPWREDLALRAAAALEQQGVAAAPVPTVF 465
 
Name Accession Description Interval E-value
PRK09201 PRK09201
AtzE family amidohydrolase;
1-229 3.00e-119

AtzE family amidohydrolase;


Pssm-ID: 236409 [Multi-domain]  Cd Length: 465  Bit Score: 347.34  E-value: 3.00e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546   1 TSDGFQAESSREQTRPLLDRGLDGLRCAVLGGYFTTWCDTDARDAVARVAKALDVQDELQFPDAELARSAAFIISASEGG 80
Cdd:PRK09201  237 PQDPFQADRPAEPTAPLLDRGAEGLRIAVLGGYFAQWADPEARAAVDRVAKALGATREVELPEAARARAAAFIITASEGG 316
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  81 NQYLPALRREPERFEPHSRERLLAGAMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATLAGEQTMEINGQL 160
Cdd:PRK09201  317 NLHLPALRTRPQDFDPASRDRLLAGAMLPAAWYVQAQRFRRWFRQAVLELFEHVDVLIAPATPCSAPLIGQETMRIDGVE 396
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2329596546 161 LPIRASMGMLTQPISFLGLPVTTVPLRTAQGAPIGLQLIAAPFNEQACLRVARVLEESGITDARPAEIA 229
Cdd:PRK09201  397 LPVRANLGILTQPISFIGLPVVAVPLRTPGGLPIGVQLIAAPWREDLALRAAAALEQQGVAAAPVPTVF 465
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
3-228 6.64e-51

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 171.49  E-value: 6.64e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546   3 DGFQAESSREQTRPLLDRGLDGLRCAVLGGYFT-TWCDTDARDAVARVAKALDVQ----DELQFPDAELARSAAFIISAS 77
Cdd:COG0154   238 DPTSAPAPVPDYLAALDRDLKGLRIGVPREYFGgDGVDPEVAAAVEAAAAALEALgaevVEVDLPDLDEALAAYYTIAAA 317
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  78 EGGNQYLPALRREPERFEPHSRERLLAGAMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATLAGEQTMEIN 157
Cdd:COG0154   318 EAAANLADLLRTRPEGFGPEVRRRILLGAYYSAADYLKAQRVRALLRRDFAAAFEDYDVLLTPTTPTPAPPIGELDADID 397
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2329596546 158 GQLlPIRASMGMLTQPISFLGLPVTTVPL-RTAQGAPIGLQLIAAPFNEQACLRVARVLEESGITDARPAEI 228
Cdd:COG0154   398 PAL-AMNYLLDRFTAPANLAGLPALSVPAgFTADGLPVGLQLIGPPGDEATLLRLAAALEQALGWHRRRPPL 468
Amidase pfam01425
Amidase;
12-209 2.36e-18

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 82.73  E-value: 2.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  12 EQTRPLLDRGLDGLRCAVLGGYFTTWCDTDARDAVARVAKALD----VQDELQFPDAELARSAAFIISASEGG---NQYL 84
Cdd:pfam01425 223 PDYAEPVKKSLKGLRIGVYREDGYFDLDPEVRRAVEEALAQLEalghEVVEVDPPSLDYALPLYYLIAPAEASsnlARYD 302
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  85 --PALRREPERFEPHSRERLLA--------------GAMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATL 148
Cdd:pfam01425 303 gvPSGPDDLSELYPRTRAEGLGdevkrriilgnyalSAGYYDKYYLKAQKVRRLIRREFAGLFEELDVLLSPTAPTPAPR 382
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2329596546 149 AGEQT---MEINGQLLpirasMGMLTQPISFLGLPVTTVPL-RTAQGAPIGLQLIAAPFNEQACL 209
Cdd:pfam01425 383 LGEPDdspLVMYNLDD-----FTAGVVPVNLAGLPAISLPAgFTADGLPVGVQIIGKPGDEETLL 442
 
Name Accession Description Interval E-value
PRK09201 PRK09201
AtzE family amidohydrolase;
1-229 3.00e-119

AtzE family amidohydrolase;


Pssm-ID: 236409 [Multi-domain]  Cd Length: 465  Bit Score: 347.34  E-value: 3.00e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546   1 TSDGFQAESSREQTRPLLDRGLDGLRCAVLGGYFTTWCDTDARDAVARVAKALDVQDELQFPDAELARSAAFIISASEGG 80
Cdd:PRK09201  237 PQDPFQADRPAEPTAPLLDRGAEGLRIAVLGGYFAQWADPEARAAVDRVAKALGATREVELPEAARARAAAFIITASEGG 316
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  81 NQYLPALRREPERFEPHSRERLLAGAMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATLAGEQTMEINGQL 160
Cdd:PRK09201  317 NLHLPALRTRPQDFDPASRDRLLAGAMLPAAWYVQAQRFRRWFRQAVLELFEHVDVLIAPATPCSAPLIGQETMRIDGVE 396
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2329596546 161 LPIRASMGMLTQPISFLGLPVTTVPLRTAQGAPIGLQLIAAPFNEQACLRVARVLEESGITDARPAEIA 229
Cdd:PRK09201  397 LPVRANLGILTQPISFIGLPVVAVPLRTPGGLPIGVQLIAAPWREDLALRAAAALEQQGVAAAPVPTVF 465
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
3-228 6.64e-51

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 171.49  E-value: 6.64e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546   3 DGFQAESSREQTRPLLDRGLDGLRCAVLGGYFT-TWCDTDARDAVARVAKALDVQ----DELQFPDAELARSAAFIISAS 77
Cdd:COG0154   238 DPTSAPAPVPDYLAALDRDLKGLRIGVPREYFGgDGVDPEVAAAVEAAAAALEALgaevVEVDLPDLDEALAAYYTIAAA 317
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  78 EGGNQYLPALRREPERFEPHSRERLLAGAMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATLAGEQTMEIN 157
Cdd:COG0154   318 EAAANLADLLRTRPEGFGPEVRRRILLGAYYSAADYLKAQRVRALLRRDFAAAFEDYDVLLTPTTPTPAPPIGELDADID 397
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2329596546 158 GQLlPIRASMGMLTQPISFLGLPVTTVPL-RTAQGAPIGLQLIAAPFNEQACLRVARVLEESGITDARPAEI 228
Cdd:COG0154   398 PAL-AMNYLLDRFTAPANLAGLPALSVPAgFTADGLPVGLQLIGPPGDEATLLRLAAALEQALGWHRRRPPL 468
Amidase pfam01425
Amidase;
12-209 2.36e-18

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 82.73  E-value: 2.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  12 EQTRPLLDRGLDGLRCAVLGGYFTTWCDTDARDAVARVAKALD----VQDELQFPDAELARSAAFIISASEGG---NQYL 84
Cdd:pfam01425 223 PDYAEPVKKSLKGLRIGVYREDGYFDLDPEVRRAVEEALAQLEalghEVVEVDPPSLDYALPLYYLIAPAEASsnlARYD 302
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  85 --PALRREPERFEPHSRERLLA--------------GAMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATL 148
Cdd:pfam01425 303 gvPSGPDDLSELYPRTRAEGLGdevkrriilgnyalSAGYYDKYYLKAQKVRRLIRREFAGLFEELDVLLSPTAPTPAPR 382
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2329596546 149 AGEQT---MEINGQLLpirasMGMLTQPISFLGLPVTTVPL-RTAQGAPIGLQLIAAPFNEQACL 209
Cdd:pfam01425 383 LGEPDdspLVMYNLDD-----FTAGVVPVNLAGLPAISLPAgFTADGLPVGVQIIGKPGDEETLL 442
PRK08310 PRK08310
amidase; Provisional
43-215 8.29e-13

amidase; Provisional


Pssm-ID: 181375 [Multi-domain]  Cd Length: 395  Bit Score: 66.55  E-value: 8.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  43 RDAVARVAKALDVQDELQFPDAELAR-SAAF-IISASEGGNQYLPALRREPERFEPHSRERLLAGAMIPSAWYIQAQRFR 120
Cdd:PRK08310  220 EAALARLRPHLGPAKPASVPPLSLDEwYEAFrVLQAAEAWETHGAWISSGNPQLGPGVADRFAAGAEVTADQVEAARARR 299
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546 121 AHARQAFKTLFAQADVLIAPATPRSATLAGEqTMEingQLLPIRASMGMLTQPISFLGLPVTTVPLRTAQGAPIGLQLIA 200
Cdd:PRK08310  300 AAFARELAALLGPDAVLLLPTVPGAAPLRGA-PFE---ALEAYRERALRLLCIAGLAGLPQISLPLASVDGAPFGLSLIG 375
                         170
                  ....*....|....*
gi 2329596546 201 APFNEQACLRVARVL 215
Cdd:PRK08310  376 PRGSDRSLLALAQTI 390
PRK07235 PRK07235
amidase; Provisional
17-219 4.56e-11

amidase; Provisional


Pssm-ID: 235979 [Multi-domain]  Cd Length: 502  Bit Score: 61.56  E-value: 4.56e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  17 LLDRGLDGLRCAVLGGYFTtWCDTDA------RDAVARVAKALDVQDELQFPDAELARSAAFIIsASEGGNQ-------- 82
Cdd:PRK07235  269 ALDRGVKGLKIGILREGFG-LPNSEPevdeavRAAAKRLEDLGATVEEVSIPLHRLALAIWNPI-ATEGATAqmmlgngy 346
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  83 -------YLPAL--------RREPERFEPHSRERLLAGAMIPS----AWYIQAQRFRAHARQAFKTLFAQADVLIAPATP 143
Cdd:PRK07235  347 gfnwkglYDTGLldafgagwRERADDLSETVKLVMLLGQYGLEryhgRYYAKARNLARRLRAAYDEALRKYDLLVMPTTP 426
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2329596546 144 RSATLAGEQTMEINGQLlpIRAsMGML--TQPISFLGLPVTTVPLRTAQGAPIGLQLIAAPFNEQACLRVARVLEESG 219
Cdd:PRK07235  427 MVATPLPAPDASREEYV--SRA-LEMIanTAPFDVTGHPAMSVPCGLVDGLPVGLMLVGRHFDEATILRAAAAFEASG 501
PRK07487 PRK07487
amidase; Provisional
106-219 5.50e-07

amidase; Provisional


Pssm-ID: 236029 [Multi-domain]  Cd Length: 469  Bit Score: 49.58  E-value: 5.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546 106 AMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATLAGEQTMEINGQLLPIRASMGMLTqpISFLGLPVTTVP 185
Cdd:PRK07487  346 RPLDLAGYMNALARRATLTRQWQLFFEDYPLLLMPVSAELPFPDDLDRQGAEGFRRVWEAQLPQIA--LPFMGLPGLSVP 423
                          90       100       110
                  ....*....|....*....|....*....|....
gi 2329596546 186 LRTAQGAPIGLQLIAAPFNEQACLRVARVLEESG 219
Cdd:PRK07487  424 TGLVGGVPVGVQLVAGRFREDLCLAAGEAIEARG 457
PRK06169 PRK06169
putative amidase; Provisional
18-217 5.96e-06

putative amidase; Provisional


Pssm-ID: 180437 [Multi-domain]  Cd Length: 466  Bit Score: 46.55  E-value: 5.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  18 LDRGLDGLRCAVLG--GYFTtwCDTDARDAVARVAKALD------VQDELQFPD-AEL------ARSAAFIISASEGGNQ 82
Cdd:PRK06169  253 LDRDVRGLRIAYSPtlGYVD--VDPEVAALVAQAVQRLAalgarvEEVDPGFSDpVEAfhvlwfAGAARLLRALPPGQRA 330
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  83 YL-PALRREPERfephsrerllaGAMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATLAGEQTMEinGQLL 161
Cdd:PRK06169  331 LLdPGLRRIAER-----------GATYSASDYLDATAVRAALGARMGAFHERYDLLLTPTLPIPAFEAGHDVPP--GSGL 397
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2329596546 162 PIRASMGMLTQPISFLGLPVTTVPL-RTAQGAPIGLQLIAAPFNEQACLRVARVLEE 217
Cdd:PRK06169  398 TDWTQWTPFTYPFNLTQQPAASVPCgFTAAGLPVGLQIVGPRHSDDLVLRVARAYEQ 454
PRK08186 PRK08186
allophanate hydrolase; Provisional
87-215 7.06e-04

allophanate hydrolase; Provisional


Pssm-ID: 236177 [Multi-domain]  Cd Length: 600  Bit Score: 40.21  E-value: 7.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2329596546  87 LRREPERFEPHSRERLLAGAMIPSAWYIQAQRFRAHARQAFKTLFAQADVLIAPATPRSATLAgeqTMEINgqllPIR-- 164
Cdd:PRK08186  320 LEAHPDAVDPVVRGIIAGAAAFSAADAFRALYRLAELRRAAEAVLAGIDALLVPTAPTHPTIA---EVAAD----PIGln 392
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2329596546 165 ASMGMLTQPISFLGLPVTTVP-LRTAQGAPIGLQLIAAPFNEQACLRVARVL 215
Cdd:PRK08186  393 SRLGTYTNFVNLLDLCALAVPaGFRADGLPFGVTLIAPAFADQALADLAARL 444
PRK06529 PRK06529
amidase; Provisional
171-220 1.81e-03

amidase; Provisional


Pssm-ID: 180608 [Multi-domain]  Cd Length: 482  Bit Score: 39.03  E-value: 1.81e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2329596546 171 TQPISFLGLPVTTVPL-RTAQGAPIGLQLIAAPFNEQACLRVARVLEESGI 220
Cdd:PRK06529  429 TALANLTGQPAISLPTyETKEGLPMGVQLIAAKGREDLLLGIAEQFEAAGL 479
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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