|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-995 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1133.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 1 MLLAEVSIRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 81 TSRNLEAVTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGIDPPVVQKFDVGAAPILSIALAGD-VPMAEMTRIAKDE 159
Cdd:COG0841 81 TSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDdLDELELSDYAERN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 160 VKQRLQQISGVGNVDLIGGREREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKTGTSELTLKTRGEVKSAAEI 239
Cdd:COG0841 161 IKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEEF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 240 ADILIPGPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERrGITAAVP 319
Cdd:COG0841 241 ENIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE-GVELTIV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 320 TDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILV 399
Cdd:COG0841 320 YDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 400 DDAIVVIENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSAAVLLSMLVSFT 479
Cdd:COG0841 400 DDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 480 LTPMLSSRIMRQQHGHAPGLFARLFNKMFGAVERGYAGVLRWSLRWPWTTVLIALLSLFGSCALVTRVPAEFLPPEDQSQ 559
Cdd:COG0841 480 LTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQ 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 560 FAVNVELPTGTALEATIETSEAVAADLRANlPQIKDTFTTIGGGAVGQ-VNRARITVTLERPKQRGFSQQDAMKWTRERL 638
Cdd:COG0841 560 IIVSVQLPPGTSLERTEAVVRQVEEILLEV-PEVESVFSVVGFSGGGSgSNSGTIFVTLKPWDERDRSADEIIARLREKL 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 639 ANVEGAMFTVDQLDPfgnDGGFRSQPIQFSIRGTDLNEVVAAAEALKGQLAETGKFVDLDTSYRGGKPEVAIAVDRNKAA 718
Cdd:COG0841 639 AKIPGARVFVFQPPA---GGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAA 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 719 DLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLGNIKVRSASGRLVDLSAVVRVERGEGPSEIE 798
Cdd:COG0841 716 ALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGPSSIN 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 799 RQNRLRQVLVLAALND-VTLGEAQQIVTDAAKRVV-PSKLQTSFMGDAEVMQESFESMIFALALAIILVYMILAAQFDSL 876
Cdd:COG0841 796 RYNGQRSVTVSANLAPgVSLGEALAAIEELAAELKlPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQFESF 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 877 IQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFANSEREKGAVITEALVQAGTIRLRPIV 956
Cdd:COG0841 876 IQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLRLRPIL 955
|
970 980 990
....*....|....*....|....*....|....*....
gi 2388338994 957 MTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:COG0841 956 MTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFST 994
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-995 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 809.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 3 LAEVSIRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 83 RNLEAVTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGIDPPVVQKFDVGAAPILSIALAGD---VPMAEMTRIAKDE 159
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPdgsYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 160 VKQRLQQISGVGNVDLIGGREREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKTGTSELTLKTRGEVKSAAEI 239
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 240 ADILIPGPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERrGITAAVP 319
Cdd:pfam00873 241 EKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ-GVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 320 TDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILV 399
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 400 DDAIVVIENIYRHLEM-GKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSAAVLLSMLVSF 478
Cdd:pfam00873 400 DDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVAL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 479 TLTPMLSSRIMRQQHGHAPGLFARLFNKMFGAVERGYAGVLRWSLRWPWTTVLIALLSLFGSCALVTRVPAEFLPPEDQS 558
Cdd:pfam00873 480 TLTPALCATLLKPRREPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 559 QFAVNVELPTGTALEATIETSEAVAADLRANlPQIKDTFTTIG---GGAVGQVNRARITVTL----ERPKQRGfSQQDAM 631
Cdd:pfam00873 560 VFVTSAQLPPGVSLDQTQRVMKQVEKILKEK-PEVESVFAVTGfafSGDNNGPNSGDAFISLkpwkERPGPEK-SVQALI 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 632 KWTRERLANVEGA---MFTVDQLDPFGNDGGFRSQpIQFSIRGTDLNEVVAAAEALKGQLAETGKFVDLDTSYRGGKPEV 708
Cdd:pfam00873 638 ERLRKALKQIPGAnvfLFQPIQLRGLGTISGFRSD-LQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQL 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 709 AIAVDRNKAADLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLGNIKVRSASGRLVDLSAVVRV 788
Cdd:pfam00873 717 QVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFAKI 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 789 ERGEGPSEIERQNRLRQVLVLAALND-VTLGEAQQIVTDAAKRV-VPSKLQTSFMGDAEVMQESFESMIFALALAIILVY 866
Cdd:pfam00873 797 EWGYGPPSINRYNGFRSIVISGNVAAgDSLGDAMEAMAQIAKQVkLPPGYGYTWTGQFEQEQLAGNSLPILIALALLVVF 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 867 MILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFANSERE-KGAVITEALV 945
Cdd:pfam00873 877 LVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREqEGKSLEEAIL 956
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|
gi 2388338994 946 QAGTIRLRPIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:pfam00873 957 EACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTST 1006
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
6-995 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 755.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 6 VSIRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTSRNL 85
Cdd:NF033617 3 VFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 86 EAVTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGI-DPPVVQKFDVGAAPILSIALAGD-VPMAEMTRIAKDEVKQR 163
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEApDPPVYRKANSADTPIMYIGLTSEeMPRGQLTDYAERVLAPK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 164 LQQISGVGNVDLIGGREREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKTGTSELTLKTRGEVKSAAEIADIL 243
Cdd:NF033617 163 LSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 244 I-PGPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERrGITAAVPTDN 322
Cdd:NF033617 243 IkYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPK-NIKVNVLYDR 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 323 SVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDA 402
Cdd:NF033617 322 TRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 403 IVVIENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSAAVLLSMLVSFTLTP 482
Cdd:NF033617 402 IVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTP 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 483 MLSSRIMrqQHGHAPGLFARLFNKMFGAVERGYAGVLRWSLRWPWTTVLIALLSLFGSCALVTRVPAEFLPPEDQSQFAV 562
Cdd:NF033617 482 MMCSRLL--KANEKPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 563 NVELPTGTALEATIETSEAVAADLRAnLPQIKDTFTTIGGGAVGQVNRARITVTLERPKQRGFSQQDAMKWTRERLANVE 642
Cdd:NF033617 560 MIQAPQSISLDYMSAKMRDVEKILSS-DPEVQSLTSFNGVGGNPGDNTGFGIINLKPWDERDVSAQEIIDRLRPKLAKVP 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 643 GAMFTVDQLDPFGNDGGFRSQPIQFSIRGTDLNEVVAAAEALKGQLAETGKFVDLDTSYRGGKPEVAIAVDRNKAADLSV 722
Cdd:NF033617 639 GMDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLGI 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 723 PIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLGNIKVRSASGRLVDLSAVVRVERGEGPSEIERQNR 802
Cdd:NF033617 719 SMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFNQ 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 803 LRQVLVLAALND-VTLGEAQQIVTDAAKRVVPSKLQTSFMGDAEVMQESFESMIFALALAIILVYMILAAQFDSLIQPIT 881
Cdd:NF033617 799 FNSATLSFNLAPgVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLT 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 882 IMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFANS-EREKGAVITEALVQAGTIRLRPIVMTAA 960
Cdd:NF033617 879 ILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANElQRHQGLSRREAIYQAAALRLRPILMTTL 958
|
970 980 990
....*....|....*....|....*....|....*
gi 2388338994 961 ATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:NF033617 959 AMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGT 993
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
7-995 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 585.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 7 SIRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTSRNLE 86
Cdd:COG3696 9 SLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSISRF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 87 AVTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGIDPpvvqkfdvGAAPILS-------IAL---AGDVPMAEMTRIA 156
Cdd:COG3696 89 GLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTP--------ELGPISTglgeiyqYTLesdPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 157 KDEVKQRLQQISGVGNVDLIGGREREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKTGTSELTLKTRGEVKSA 236
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 237 AEIADILIPGPPGAVVRIRDVAEVLDDVEDARSASFLNGNS-ALALVVKKQSGANVVSLAEQVREVLDEMRPDLERrGIT 315
Cdd:COG3696 241 EDIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGeVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPE-GVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 316 AaVPT-DNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLS 394
Cdd:COG3696 320 I-VPFyDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAID 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 395 IGILVDDAIVVIENIYRHLEM------GKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSA 468
Cdd:COG3696 399 FGIIVDGAVVMVENILRRLEEnraagtPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIF 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 469 AVLLSMLVSFTLTPMLSSRIMRQQHGHAPGLFARLFnkmfgavERGYAGVLRWSLRWPWTTVLIALLSLFGSCALVTRVP 548
Cdd:COG3696 479 ALLGALLLSLTLVPVLASLLLRGKVPEKENPLVRWL-------KRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLG 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 549 AEFLPPEDQSQFAVNVELPTGTALEATIETSEAVAADLRAnLPQIKDTFTTIGGGAVG----QVNRARITVTLERPKQ-- 622
Cdd:COG3696 552 SEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKS-FPEVESVVSRTGRAEDAtdpmGVNMSETFVILKPRSEwr 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 623 RGFSQQDAMKWTRERLANVEGAMFTVdqldpfgndggfrSQPIQ---------------FSIRGTDLNEVVAAAEALKGQ 687
Cdd:COG3696 631 SGRTKEELIAEMREALEQIPGVNFNF-------------SQPIQmrvdellsgvradvaVKIFGDDLDVLRRLAEQIEAV 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 688 LAETGKFVDLDTSYRGGKPEVAIAVDRNKAADLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESL 767
Cdd:COG3696 698 LKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAI 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 768 GNIKVRSASGRLVDLSAVVRVERGEGPSEIERQNRLRQVLVLAALNDVTLG----EAQQIVTDAAKrvVPSKLQTSFMGD 843
Cdd:COG3696 778 RNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGsfvaEAQAKVAEQVK--LPPGYYIEWGGQ 855
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 844 AEVMQESFESMIFALALAIILVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTA 923
Cdd:COG3696 856 FENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNG 935
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2388338994 924 ILLVDFANSEREKGAVITEALVQAGTIRLRPIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:COG3696 936 VVLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITST 1007
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
8-995 |
6.16e-164 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 511.97 E-value: 6.16e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 8 IRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTSR-NLE 86
Cdd:TIGR00915 6 IDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSsDSD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 87 AVTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGIDPPVVQKFDVGAAPILSIALAGDVPMA---EMTRIAKDEVKQR 163
Cdd:TIGR00915 86 GSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMtkeDLSDYAASNMVDP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 164 LQQISGVGNVDLIGGrEREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFI------KTGTSELTLKTRGEVKSAA 237
Cdd:TIGR00915 166 LSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLgglpavPGQQLNATIIAQTRLQTPE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 238 EIADILIP-GPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERrGITA 316
Cdd:TIGR00915 245 QFENILLKvNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ-GMKY 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 317 AVPTDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIG 396
Cdd:TIGR00915 324 VYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIG 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 397 ILVDDAIVVIENIYRHL-EMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSAAVLLSML 475
Cdd:TIGR00915 404 LLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 476 VSFTLTPMLSSRIMR-----QQHGHAPGLFArLFNKMFGAVERGYAGVLRWSLRWPWTTVLIALLSLFGSCALVTRVPAE 550
Cdd:TIGR00915 484 VALILTPALCATMLKpiekgEHHEKKGGFFG-WFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPTS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 551 FLPPEDQSQFAVNVELPTGTALEATIETSEAVAADLRAN-LPQIKDTFTTIGGGAVGQ-VNRARITVTL----ERPKQRG 624
Cdd:TIGR00915 563 FLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKeKANVESVFTVNGFSFAGRgQNMGMAFIRLkdweERTGKEN 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 625 FSQQDAMKWTRErLANVEGAM---FTVDQLDPFGNDGGFRSQPIQFSirGTDLNEVVAAAEALKGQLAETGKFVDLDTSY 701
Cdd:TIGR00915 643 SVFAIAGRATGH-FMQIKDAMviaFVPPAILELGNATGFDFFLQDRA--GLGHEALLQARNQLLGLAAQNPALTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 702 RGGKPEVAIAVDRNKAADLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLGNIKVRSASGRLVD 781
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVP 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 782 LSAVVRVERGEGPSEIERQNRLRQVLVLAALN-DVTLGEAQQIVTDAAKRVVPS-KLQTSFMGDAEVMQESFESMIFALA 859
Cdd:TIGR00915 800 FSAFATVRWEYGSPQLERYNGLPSMEILGSAApGVSTGQAMAAMEAIAQKLPPGfGFSWTGMSYEERLSGSQAPALYALS 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 860 LAIilVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFANSEREKGAV 939
Cdd:TIGR00915 880 LLV--VFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKS 957
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
gi 2388338994 940 ITEALVQAGTIRLRPIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:TIGR00915 958 IVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTAT 1013
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
8-1019 |
7.18e-157 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 493.48 E-value: 7.18e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 8 IRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTSRNLEA 87
Cdd:PRK10503 17 ILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 88 VTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGI-DPPVVQKFDVGAAPILSIALAGD-VPMAEMTRIAKDEVKQRLQ 165
Cdd:PRK10503 97 ASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLpNPPVYSKVNPADPPIMTLAVTSTaMPMTQVEDMVETRVAQKIS 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 166 QISGVGNVDLIGGREREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKTGTSELTLKTRGEVKSAAEIADILIP 245
Cdd:PRK10503 177 QVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEYRQLIIA 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 246 GPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERrGITAAVPTDNSVF 325
Cdd:PRK10503 257 YQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPK-SVKVTVLSDRTTN 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 326 VEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVV 405
Cdd:PRK10503 336 IRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVV 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 406 IENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSAAVLLSMLVSFTLTPMLS 485
Cdd:PRK10503 416 IENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMC 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 486 SRIMRQQHGHAPGLFARLFNKMFGAVERGYAGVLRWSLRWPWTTVLIALLSLFGSCALVTRVPAEFLPPEDQSQFAVNVE 565
Cdd:PRK10503 496 ARMLSQESLRKQNRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGIIQGTLQ 575
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 566 LPTGTALEATIETSEAVAADLRANlPQIKDTFTTIG-GGAVGQVNRARITVTLERPKQRGFSQQDAMKWTRERLANVEGA 644
Cdd:PRK10503 576 APQSSSFANMAQRQRQVADVILQD-PAVQSLTSFVGvDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVAKVPGV 654
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 645 MFTVDQLDPFGNDGGFRSQPIQFSIRGTDLNEVVAAAEALKGQLAETGKFVDLDTSYRGGKPEVAIAVDRNKAADLSVPI 724
Cdd:PRK10503 655 DLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISM 734
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 725 ASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLGNIKVRSASGRLVDLSAVVRVERGEGPSEIerqNRLR 804
Cdd:PRK10503 735 ADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIATIEQRFGPLSI---NHLD 811
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 805 Q----VLVLAALNDVTLGEAQQIVTDAAKRV-VPSKLQTSFMGDAEVMQESFESMIFALALAIILVYMILAAQFDSLIQP 879
Cdd:PRK10503 812 QfpstTISFNVPDGYSLGDAVQAIMDTEKTLnLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGVLYESFIHP 891
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 880 ITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFA-NSEREKGAVITEALVQAGTIRLRPIVMT 958
Cdd:PRK10503 892 ITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFAlAAEREQGMSPRDAIYQACLLRFRPILMT 971
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2388338994 959 AAATIFGMIPVALALGEGGETRAPMAVIVIGGMITSTVLTLVVVPVVYLLFDRMVTSRSMR 1019
Cdd:PRK10503 972 TLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLFDRLALYTKSR 1032
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
8-994 |
3.98e-152 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 480.38 E-value: 3.98e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 8 IRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTSRNLEA 87
Cdd:PRK10614 8 IYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 88 VTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGI-DPPVVQKFDVGAAPILSIALAGDV-PMAEMTRIAKDEVKQRLQ 165
Cdd:PRK10614 88 STRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSDTySQGQLYDFASTQLAQTIS 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 166 QISGVGNVDLIGGREREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKTGTSELTLKTRGEVKSAAEIADILIP 245
Cdd:PRK10614 168 QIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLIIH 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 246 GPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERrGITAAVPTDNSVF 325
Cdd:PRK10614 248 YNNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPA-AIDLQIAQDRSPT 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 326 VEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVV 405
Cdd:PRK10614 327 IRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 406 IENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSAAVLLSMLVSFTLTPMLS 485
Cdd:PRK10614 407 LENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPMMC 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 486 SRIMRQQHGHAPGLfARLFNKMFGAVERGYAGVLRWSL---RWpwttVLIALLSLFG-SCALVTRVPAEFLPPEDQSQFA 561
Cdd:PRK10614 487 AWLLKSSKPREQKR-LRGFGRMLVALQQGYGRSLKWVLnhtRW----VGVVLLGTIAlNVWLYISIPKTFFPEQDTGRLM 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 562 VNVELPTGTALEATIETSEAVAADLRANlPQIkDTFTTIGGGavGQVNRARITVTLERPKQRGFSQQDAMKWTRERLANV 641
Cdd:PRK10614 562 GFIQADQSISFQAMRGKLQDFMKIIRDD-PAV-DNVTGFTGG--SRVNSGMMFITLKPLSERSETAQQVIDRLRVKLAKE 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 642 EGAMFTVDQLDPFGNDGGFRSQPIQFSIRGTDLNEVVAAAEALKGQLAETGKFVDLDTSYRGGKPEVAIAVDRNKAADLS 721
Cdd:PRK10614 638 PGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKALAALPELADVNSDQQDKGAEMALTYDRDTMARLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 722 VPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLGNIKVRSASGRLVDLSAVVRVERGEGPSEIERQN 801
Cdd:PRK10614 718 IDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQG 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 802 rLRQVLVLA--ALNDVTLGEAqqivTDAAKRV-----VPSKLQTSFMGDAEVMQESFESMIFALALAIILVYMILAAQFD 874
Cdd:PRK10614 798 -LSAASTISfnLPTGKSLSDA----SAAIERAmtqlgVPSTVRGSFAGTAQVFQETMNSQLILILAAIATVYIVLGILYE 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 875 SLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFA-NSEREKGAVITEALVQAGTIRLR 953
Cdd:PRK10614 873 SYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFAlEAQRNGNLTAQEAIFQACLLRFR 952
|
970 980 990 1000
....*....|....*....|....*....|....*....|.
gi 2388338994 954 PIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITS 994
Cdd:PRK10614 953 PIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMS 993
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-995 |
1.64e-137 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 441.20 E-value: 1.64e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 1 MLLAEVSIRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 81 TSRNLEAVTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGIDPPVVQKFDVGAAPILSIAL-AGDVPMAEMTRIAKDE 159
Cdd:PRK09579 81 TSVSRQNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFySEEMSNPQITDYLSRV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 160 VKQRLQQISGVGNVDLIGGREREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKTGTSELTLKTRGEVKSAAEI 239
Cdd:PRK09579 161 IQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEAF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 240 ADILIPGPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERrGITAAVP 319
Cdd:PRK09579 241 AAIPVKTSGDSRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPP-NLKVSIA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 320 TDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILV 399
Cdd:PRK09579 320 YDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 400 DDAIVVIENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSAAVLLSMLVSFT 479
Cdd:PRK09579 400 DDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 480 LTPMLSSRIMRQQHgHAPGLFARLfNKMFGAVERGYAGVLRWSLRWPWTTVLIALLSLFGSCALVTRVPAEFLPPEDQSQ 559
Cdd:PRK09579 480 LSPMMCALLLRHEE-NPSGLAHRL-DRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELAPEEDQGI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 560 FAVNVELPTGTALEATIETSEAVAADLRAnLPQIKDTFTTIGGGAVgqvnRARITVTLERP-KQRGFSQQDAMKWTRERL 638
Cdd:PRK09579 558 IFMMSSSPQPANLDYLNAYTDEFTPIFKS-FPEYYSSFQINGFNGV----QSGIGGFLLKPwNERERTQMELLPLVQAKL 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 639 ANVEGamftvdqLDPFGND-----GGFRSQPIQFSIR-GTDLNEVVAAAEALKGQLAETGKFVDLDTSYRGGKPEVAIAV 712
Cdd:PRK09579 633 EEIPG-------LQIFGFNlpslpGTGEGLPFQFVINtANDYESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDI 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 713 DRNKAADLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLGNIKVRSASGRLVDLSAVVRVERGE 792
Cdd:PRK09579 706 DRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRA 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 793 GPSEIERQNRLRQVLVlAALNDVTLGEAQQIVTDAAKRVVPSKLQTSFMGDAE--VMQESFESMIFALALAIIlvYMILA 870
Cdd:PRK09579 786 RPRQLNQFQQLNSAII-SGFPIVSMGEAIETVQQIAREEAPEGFAFDYAGASRqyVQEGSALWVTFGLALAII--FLVLA 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 871 AQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFANSER-EKGAVITEALVQAGT 949
Cdd:PRK09579 863 AQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRhEQGLSRREAIEEAAA 942
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*.
gi 2388338994 950 IRLRPIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:PRK09579 943 IRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGT 988
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
3-995 |
1.69e-123 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 404.23 E-value: 1.69e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 3 LAEVSIRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTS 82
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 83 RNLEAVTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGI--DPPVVQKFDVGAAPILSI-ALAGDVPMAEMTRIAKDE 159
Cdd:PRK09577 81 TSSAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVrrDGIQVEKAADNIQLIVSLtSDDGRLTGVELGEYASAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 160 VKQRLQQISGVGNVDLIGGrEREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFI-KTGTSE-----LTLKTRGEV 233
Cdd:PRK09577 161 VLQALRRVEGVGKVQFWGA-EYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIgRSAVPDsapiaATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 234 KSAAEIADI-LIPGPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERr 312
Cdd:PRK09577 240 KTPEDFGAIaLRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPP- 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 313 GITAAVPTDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALS 392
Cdd:PRK09577 319 GVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 393 LSIGILVDDAIVVIENIYRHL-EMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSAAVL 471
Cdd:PRK09577 399 LAIGILVDDAIVVVENVERLMvEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIG 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 472 LSMLVSFTLTPMLSSRIMR---QQHGHAPGLFArLFNKMFGAVERGYA----GVLRWSLRWpwttvLIALLSLFGSCALV 544
Cdd:PRK09577 479 FSAFLALSLTPALCATLLKpvdGDHHEKRGFFG-WFNRFVARSTQRYAtrvgAILKRPLRW-----LVVYGALTAAAALL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 545 -TRVPAEFLPPEDQSQFAVNVELPTGTALEATIETSEAVAADLRANLPqIKDTFTTIGGGAVGQ-VNRARITVTLERPKQ 622
Cdd:PRK09577 553 fTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP-VAYTFALGGFNLYGEgPNGGMIFVTLKDWKE 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 623 RGFSQQDA---MKWTRERLANVEGAM-FTVDQ--LDPFGNDGGFrsqPIQFSIRGT-DLNEVVAAAEALKGQLAETGKFV 695
Cdd:PRK09577 632 RKAARDHVqaiVARINERFAGTPNTTvFAMNSpaLPDLGSTSGF---DFRLQDRGGlGYAAFVAAREQLLAEGAKDPALT 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 696 DLDTSYRGGKPEVAIAVDRNKAADLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLGNIKVRSA 775
Cdd:PRK09577 709 DLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNA 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 776 SGRLVDLSAVVRVERGEGPSEIERQNRLRQVLVL-AALNDVTLGEAQQIVTDAAkRVVPSKLQTSFMGDA--EVMQESFE 852
Cdd:PRK09577 789 QGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINgSAAPGHSSGEAMAAIERIA-ATLPAGIGYAWSGQSfeERLSGAQA 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 853 SMIFALAlaIILVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFANS 932
Cdd:PRK09577 868 PMLFALS--VLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKD 945
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2388338994 933 EREKGAVITEALVQAGTIRLRPIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:PRK09577 946 LVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITAT 1008
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
7-995 |
5.03e-122 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 400.68 E-value: 5.03e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 7 SIRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTSRNLE 86
Cdd:TIGR00914 9 SVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 87 AVTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGIDP---PV------VQKFDVGAAPILSIALAGDVPMAEMTRIAK 157
Cdd:TIGR00914 89 GLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPemgPIstglgeIFLYTVEAEEGARKKDGGAYTLTDLRTIQD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 158 DEVKQRLQQISGVGNVDLIGGREREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKTGTSELTLKTRGEVKSAA 237
Cdd:TIGR00914 169 WIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQVQSMD 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 238 EIADILIPGPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERrGITAA 317
Cdd:TIGR00914 249 DIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPE-GVEIV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 318 VPTDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSlsIGI 397
Cdd:TIGR00914 328 TTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGALD--FGL 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 398 LVDDAIVVIENIYRHLEMG----------KPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVS 467
Cdd:TIGR00914 406 IVDGAVVIVENAHRRLAEAqhhhgrqltlKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPMAFTVV 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 468 AAVLLSMLVSFTLTPMLSSRIMRqqhghapGLFARLFNKMFGAVERGYAGVLRWSLRWPWTTVLIALLSLFGSCALVTRV 547
Cdd:TIGR00914 486 LALAGAMILSLTFVPAAVALFIR-------GKVAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRV 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 548 PAEFLPPEDQSQFAVN-VELPtGTALEATIETSEAVAADLRAnLPQIKDTFTTIGGGAVGQ----VNRARITVTLERPKQ 622
Cdd:TIGR00914 559 GGEFIPSLNEGDLAYQaLRIP-GTSLAQSVAMQQTLEKLIKS-FPEVARVFAKTGTAEIATdpmpPNASDTYIILKPESQ 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 623 ---RGFSQQDAMKWTRERLANVEGAMFTVDQldPFGND-----GGFRSqPIQFSIRGTDLNEVVAAAEALKGQLAETGKF 694
Cdd:TIGR00914 637 wpeGKKTKEDLIEEIQEATVRIPGNNYEFTQ--PIQMRfneliSGVRS-DVAVKVFGDDLDDLDATAEKISAVLKGVPGA 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 695 VDLDTSYRGGKPEVAIAVDRNKAADLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLGNI---- 770
Cdd:TIGR00914 714 ADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLpipl 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 771 -KVRSASGRLVDLSAVVRVERGEGPSEIERQNRLRQVLVLAALNDVTLGeaqQIVTDAAKRV-----VPSKLQTSFMGDA 844
Cdd:TIGR00914 794 pLSEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLG---SFVDDAKKAIaeqvkLPPGYWITWGGQF 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 845 EVMQESFESMIFALALAIILVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAI 924
Cdd:TIGR00914 871 EQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGL 950
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2388338994 925 LLVDFANSEREKGAVITEALVQAGTIRLRPIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:TIGR00914 951 VMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITAT 1021
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
3-995 |
1.43e-121 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 399.20 E-value: 1.43e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 3 LAEVSIRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTS 82
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 83 RNLEA-VTQVVMEFELEVDGVQALQDVRDKISAIERDLPQGIDPPVVQKFDVGAAPILSIALA---GDVPMAEMTRIAKD 158
Cdd:PRK10555 81 QSSGTgQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVstdGSMDKQDIADYVAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 159 EVKQRLQQISGVGNVDLIGGrEREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKtGTSEL-------TLKTRG 231
Cdd:PRK10555 161 NIQDPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLG-GTPSVdkqalnaTINAQS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 232 EVKSAAEIADI-LIPGPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLE 310
Cdd:PRK10555 239 LLQTPEQFRDItLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 311 RrGITAAVPTDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLA 390
Cdd:PRK10555 319 H-GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 391 LSLSIGILVDDAIVVIENIYRHL-EMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVSAA 469
Cdd:PRK10555 398 MVLAIGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSA 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 470 VLLSMLVSFTLTPMLSSRIMR-----QQHGHAP--GLFARLFNKMFGAVERGYAGVLRWSLRWpwttVLIALLSLFGSCA 542
Cdd:PRK10555 478 MVLSVLVAMILTPALCATLLKplkkgEHHGQKGffGWFNRMFNRNAERYEKGVAKILHRSLRW----ILIYVLLLGGMVF 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 543 LVTRVPAEFLPPEDQSQFAVNVELPTGTALEATIETSEAVAadlRANLPQIKDT----FTTIGGGAVGQ-VNRARITVTL 617
Cdd:PRK10555 554 LFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVE---KYYFTHEKDNvmsvFATVGSGPGGNgQNVARMFIRL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 618 ----ERPKQRGFSQQDAMKWTRERLANVEGAMFTVD--QLDPFGNDGGFRSQPIQFSIRGTDlnEVVAAAEALkgqLAET 691
Cdd:PRK10555 631 kdwdERDSKTGTSFAIIERATKAFNKIKEARVIASSppAISGLGSSAGFDMELQDHAGAGHD--ALMAARNQL---LALA 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 692 GKFVDLDTSYRGG---KPEVAIAVDRNKAADLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFESLG 768
Cdd:PRK10555 706 AKNPELTRVRHNGlddSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDIN 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 769 NIKVRSASGRLVDLSAVVRVERGEGPSEIERQNRLRQV-LVLAALNDVTLGEAQQIVTDAAKRvVPS--KLQTSFMGDAE 845
Cdd:PRK10555 786 LWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVeIVGEAAPGVSTGTAMDIMESLVKQ-LPNgfGLEWTAMSYQE 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 846 VMQESFESMIFALALaiILVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAIL 925
Cdd:PRK10555 865 RLSGAQAPALYAISL--LVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAIL 942
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 926 LVDFANSEREKGAVITEALVQAGTIRLRPIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:PRK10555 943 IVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISAT 1012
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
3-995 |
7.62e-116 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 383.87 E-value: 7.62e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 3 LAEVSIRRSIFATMLIAALMVFGFFSLPRIGVELFPNVEFPVVTATVVYPGADPETMETKVADPIEEALQSISGVKRMTS 82
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 83 RNLEAVT-QVVMEFELEVDGVQALQDVRDKISAIERDLPQGIDPPVVQKFDVGAAPILSIALAGDVPMAEMTRIAK---D 158
Cdd:PRK15127 81 NSDSTGTvQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDyvaA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 159 EVKQRLQQISGVGNVDLIGGrEREIKVLVDPARMTGFGLTADDVANAVRAQSLELPAGFIKtGT---------SELTLKT 229
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLG-GTppvkgqqlnASIIAQT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 230 RgeVKSAAEIADILIP-GPPGAVVRIRDVAEVLDDVEDARSASFLNGNSALALVVKKQSGANVVSLAEQVREVLDEMRPD 308
Cdd:PRK15127 239 R--LTSTEEFGKILLKvNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPF 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 309 LERrGITAAVPTDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISM 388
Cdd:PRK15127 317 FPS-GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTM 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 389 LALSLSIGILVDDAIVVIENIYRHL-EMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQFGLTVS 467
Cdd:PRK15127 396 FGMVLAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 468 AAVLLSMLVSFTLTPMLSSRIMRQ----QHGHAPGLFARLFNKMFGAVERGY----AGVLRWSLRWpwttVLIALLSLFG 539
Cdd:PRK15127 476 SAMALSVLVALILTPALCATMLKPiakgDHGEGKKGFFGWFNRMFEKSTHHYtdsvGNILRSTGRY----LVLYLIIVVG 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 540 SCALVTRVPAEFLPPEDQSQFAVNVELPTGTALEATIETSEAVAAD-LRANLPQIKDTFTTIGGGAVGQVNRARIT-VTL 617
Cdd:PRK15127 552 MAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYyLTKEKNNVESVFAVNGFGFAGRGQNTGIAfVSL 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 618 ----ERPKQRGFSQQDAMKWTReRLANVEGAM---FTVDQLDPFGNDGGFRSQPIQFSIRGTDlnevvAAAEALKGQLAE 690
Cdd:PRK15127 632 kdwaDRPGEENKVEAITMRATR-AFSQIKDAMvfaFNLPAIVELGTATGFDFELIDQAGLGHE-----KLTQARNQLLGE 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 691 TGKFVDLDTSYRGG----KPEVAIAVDRNKAADLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILYMPESLRSSFES 766
Cdd:PRK15127 706 AAKHPDMLVGVRPNgledTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDD 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 767 LGNIKVRSASGRLVDLSAVVRVERGEGPSEIERQNRLRQVLVLA-ALNDVTLGEAQQIVTDAAKRvVPSKLQTSFMGDAE 845
Cdd:PRK15127 786 IGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGqAAPGKSTGEAMELMEELASK-LPTGVGYDWTGMSY 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 846 VMQESFESMIFALALAIILVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAIL 925
Cdd:PRK15127 865 QERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAIL 944
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2388338994 926 LVDFANSEREK-GAVITEALVQAGTIRLRPIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITST 995
Cdd:PRK15127 945 IVEFAKDLMDKeGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTAT 1015
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
287-972 |
2.85e-28 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 122.66 E-value: 2.85e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 287 SGANVVSLAEQVREVLDEMRPDLERRGITAaVPTDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIP 366
Cdd:COG1033 175 SDLDRKEVVAEIRAIIAKYEDPGVEVYLTG-FPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVL 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 367 TSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVVIENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAVFV 446
Cdd:COG1033 254 LAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFL 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 447 PVAYMKGIIGRfffQFGLTVSAAVLLSMLVSFTLTPMLSS----RIMRQQHGHAPGLFARLFNKMFgavergyagvlRWS 522
Cdd:COG1033 334 SLLFSDIPPIR---DFGIVAAIGVLLAFLTSLTLLPALLSllprPKPKTRRLKKPPELGRLLAKLA-----------RFV 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 523 LRWPWTTVLIALLSLFGSCALVTRVPAEFLPPEdqsqfavnvELPtgtaleatiETSEAVAADLRanlpqIKDTFTTIGg 602
Cdd:COG1033 400 LRRPKVILVVALVLAVVSLYGISRLKVEYDFED---------YLP---------EDSPIRQDLDF-----IEENFGGSD- 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 603 gavgqvnraRITVTLERPKQRGFSQQDAMKWTRERLANVEgamftvdQLDPFGNdggfrsqpiqfsirgtdlneVVAAAE 682
Cdd:COG1033 456 ---------PLEVVVDTGEPDGLKDPEVLKEIDRLQDYLE-------SLPEVGK--------------------VLSLAD 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 683 ALKgqlaetgkfvdldtsyrggkpEVAIAVDRNKAADLSVPiasiartvrslmagdpiSDLKEGSEIYDVILYMPESLRS 762
Cdd:COG1033 500 LVK---------------------ELNQALNEGDPKYYALP-----------------ESRELLAQLLLLLSSPPGDDLS 541
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 763 SFESLGNIKVRsASGRLVDLSAvvrvergegpSEIERQnrlrqvlvlaalndvtlgeAQQIVTDAAKRVVPSKLQTSFMG 842
Cdd:COG1033 542 RFVDEDYSAAR-VTVRLKDLDS----------EEIKAL-------------------VEEVRAFLAENFPPDGVEVTLTG 591
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 843 D----AEVMQESFESMIFALALAIILVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGL 918
Cdd:COG1033 592 SavlfAAINESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGI 671
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 2388338994 919 VTKTAILLVDFANSEREKGAVITEALVQAGTIRLRPIVMTAAATIFGMIPVALA 972
Cdd:COG1033 672 GVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFS 725
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
271-484 |
7.58e-19 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 92.23 E-value: 7.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 271 SFLNGNSALALV---VKKQSGANVVSLAEQVREVLDEMRPDlerRGITAAVpTDNSVFVEHAIGDVKFDLILGAILTIVI 347
Cdd:COG1033 542 RFVDEDYSAARVtvrLKDLDSEEIKALVEEVRAFLAENFPP---DGVEVTL-TGSAVLFAAINESVIESQIRSLLLALLL 617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 348 ILVFL----HDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVVIENIYRHLEMGKPRMRAA 423
Cdd:COG1033 618 IFLLLllafRSLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAI 697
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2388338994 424 LDATSEIGLAVIATTLSIVAVFVPVAY--MKGIIgrfffQFGLTVSAAVLLSMLVSFTLTPML 484
Cdd:COG1033 698 RRALRTTGKAILFTSLTLAAGFGVLLFssFPPLA-----DFGLLLALGLLVALLAALLLLPAL 755
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
703-999 |
1.92e-13 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 75.14 E-value: 1.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 703 GGKPEVAIAVDRNKAADLSVPIASIARTVRSLMAGDPISDLKEGSEIYDVILympESLRSSFESLGNIKVRSASGRLVDL 782
Cdd:COG0841 179 GREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRT---NGRLKTPEEFENIVIRTNDGSVVRL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 783 SAVVRVERG-EGPSEIERQNRLRQVLV----LAALNDVTLGEAQQIVTDAAKRVVPSKLQTSFMGD-AEVMQESFESMIF 856
Cdd:COG0841 256 GDVARVEDGaEDYRSIARLNGKPAVGLaiqkQPGANALEVADAVRAKLEELQASLPEGVELTIVYDqSEFIRASIEEVVK 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 857 ALALAIILVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFANSEREK 936
Cdd:COG0841 336 TLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVVDDAIVVVENIERHMEE 415
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2388338994 937 GAVITEALVQAGTIRLRPIVMTAAATIFGMIPVALALGEGGETRAPMAVIVIGGMITSTVLTL 999
Cdd:COG0841 416 GLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVAL 478
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
233-556 |
5.64e-12 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 69.87 E-value: 5.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 233 VKSAAEIADIL--IPGPPGAVVRIRDVAEVLDDVEDARSaSFLNGNSALALVVKKQSGAN----VVSLAEQVREVLDEMR 306
Cdd:TIGR00921 90 VTNVRSAADIMrqIPGNFPLPVTMPEVRPLMSEYPRSKE-MFLSKDHTVAIIIVQLKSDAdykqVVPIYNDVERSLERTN 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 307 PDLERRGITAAVPTDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNI 386
Cdd:TIGR00921 169 PPSGKFLDVTGSPAINYDIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYAT 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 387 SMLALSLSIGILVDDAIVVIENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMkgiIGRFFFQFGLTV 466
Cdd:TIGR00921 249 TLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALS---EFPMVSEFGLGL 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 467 SAAVLLSMLVSFTLTPMLSSRImrQQHGHAPGLFARLFNKMFGAVERGYAGVLRWSLRWPWTTVLIALL----SLFGSCA 542
Cdd:TIGR00921 326 VAGLITAYLLTLLVLPALLQSI--DIGREKVKKEIIAIGGKSSEIEEELSKVLSITVRHPVPALVAALIitglGLYGAAG 403
|
330
....*....|....
gi 2388338994 543 LVTRVPAEFLPPED 556
Cdd:TIGR00921 404 IKPEVNIEKFIPQD 417
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
313-588 |
4.13e-09 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 60.78 E-value: 4.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 313 GITAAVPTDNSVFVEHAIGdVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALS 392
Cdd:TIGR03480 252 RLTGEVALSDEELATVSEG-ATVAGLLSFVLVLVLLWLALRSPRLVFAVLVTLIVGLILTAAFATLAVGHLNLISVAFAV 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 393 LSIGILVDDAIVVI----ENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAvFVPVAYmKGIIgrfffQFGLTVSA 468
Cdd:TIGR03480 331 LFIGLGVDFAIQFSlryrEERFRGGNHREALSVAARRMGAALLLAALATAAGFFA-FLPTDY-KGVS-----ELGIIAGT 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 469 AVLLSMLVSFTLTPMLsSRIMRQQHGHAPGLFARLfnkmfgavergyAGVLRWSLRWPWTTVLIALLSLFGSCALVTRVP 548
Cdd:TIGR03480 404 GMFIALFVTLTVLPAL-LRLLRPPRRRKPPGYATL------------APLDAFLRRHRRPVLGVTLILGIAALALLPQLR 470
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 2388338994 549 AEFLPPEDQSQFAVNVElpTGTALEATIETS----EAVAADLRA 588
Cdd:TIGR03480 471 FDFNPLNLQDPKTESVR--TFLELLADPDTSpysaEVLAPSAPE 512
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
236-618 |
2.40e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 58.24 E-value: 2.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 236 AAEIADILipgppGAVVRIRDVAEVLDDVEDARSASFL-NGNSALALV-VKKQSGANVVSLAEQVREVLDEMRPDlerrG 313
Cdd:COG2409 78 RAAVAALV-----ARLRADPGVAGVQDPWDDPAAGLVSeDGKAALVTVtLDGDAGDEAAEAVDALRDAVAAAPAP----G 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 314 ITAAV---PTDNSVFVEHAIGDVKFDLILGAILTIVIILVFLHDIRATFI----AALAIPTSIVATFAFMQYMGFSfNNI 386
Cdd:COG2409 149 LTVYVtgpAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLplltAGLAVGVALGLLALLAAFTDVS-SFA 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 387 SMLALSLSIGILVDDAIVVIeNIYRH-LEMGKPRMRAALDATSEIGLAVIATTLSIVA-----VFVPVAymkgiigrFFF 460
Cdd:COG2409 228 PNLLTMLGLGVGIDYALFLV-SRYREeLRAGEDREEAVARAVATAGRAVLFSGLTVAIallglLLAGLP--------FLR 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 461 QFGLTVSAAVLLSMLVSFTLTP----MLSSRIMRqqhghapgLFARLFNKMFGAVERGYAGVLRWSLRWPWTTVLIALLS 536
Cdd:COG2409 299 SMGPAAAIGVAVAVLAALTLLPallaLLGRRVFW--------PRRPRRRRAAAPESGFWRRLARAVVRRPVPVLVAAVAV 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 537 LFGSCALVTRVP-----AEFLPPED---QSQFAVNVELPTG--TALEATIETSEAVAADLRANLPQIKDTFTTIGG-GAV 605
Cdd:COG2409 371 LLALALPALGLRlglpdADSLPADSpsrQGYDALAEHFPPGsnGPLTVVVESDDDLDPADLAALDALAAALAAVPGvASV 450
|
410 420
....*....|....*....|.
gi 2388338994 606 GQVNR--------ARITVTLE 618
Cdd:COG2409 451 QPPTRpegtdgdaARLQVVPD 471
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
853-972 |
8.30e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 49.84 E-value: 8.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 853 SMIFALALAIILVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKTAILLVDFANS 932
Cdd:TIGR00921 194 DMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEE 273
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2388338994 933 EREKGAVITEALVQAGTIRLRPIVMTAAATIFGMIPVALA 972
Cdd:TIGR00921 274 ERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALS 313
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
337-482 |
2.75e-05 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 48.31 E-value: 2.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 337 LILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVVIENIYRHLEMg 416
Cdd:COG4258 645 LLLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTEGLLDKGEL- 723
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2388338994 417 kPRMRAAldatseIGLAVIATTLSI-VAVF--VPVAYMkgiigrfffqFGLTVSAAVLLSMLVSFTLTP 482
Cdd:COG4258 724 -ARTLLS------ILLAALTTLLGFgLLAFssTPALRS----------FGLTVLLGILLALLLAPLLAP 775
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
337-475 |
4.12e-05 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 47.74 E-value: 4.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 337 LILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVVIENIYR-HLEM 415
Cdd:pfam02460 645 IVITLICMFIVCFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYHFVRsRGDT 724
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 416 GKPRMRAALDAtseIGLAVIATTLSIVAVFVPVAYMKGIIGRFFFQfglTVSAAVLLSML 475
Cdd:pfam02460 725 PAERVVDALEA---LGWPVFQGGLSTILGVLVLLFVPSYMVVVFFK---TVFLVVAIGLL 778
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
338-484 |
4.45e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 47.52 E-value: 4.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 338 ILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVVIENIYRHLEMGK 417
Cdd:TIGR00921 574 IAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHLAERYFEERKEHG 653
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2388338994 418 PRmRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGIIGRfffQFGLTVSAAVLLSMLVSFTLTPML 484
Cdd:TIGR00921 654 PK-EAITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMR---NFGLVQGIGVLSSLTAALVVFPAL 716
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
252-576 |
5.61e-05 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 47.27 E-value: 5.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 252 VRIRDVAEVLDDVEDARSASFL--NGNSALALVVKKQSGANVVSLAEQVREVLDEMRPDLERRGITAAV--PTDNSVFVE 327
Cdd:TIGR00833 89 ADIMHVISVVDFWGPPEAAEGLrsDDGKATIIIVNLAGEKGQKEAQEAINAVRRIVEQTNAPDGLTVHVtgPLATIADIL 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 328 HAIGDVKFDLILGAILTIVIILVFLHDIRATFIAALA-IPTSIVATFAFMQYMG-FSFNNISMLAL----SLSIGILVDD 401
Cdd:TIGR00833 169 ESGDKDMNRITATTGIIVLIILLLVYRSPITMLVPLVsVGFSVVVAQGIVSLLGiPGLIGVNAQTTvlltALVIGAGTDY 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 402 AIVVIENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYmkGIIGrFFFQFGLTVSAAVLLSMLVSFTLT 481
Cdd:TIGR00833 249 AVFLTGRYHEERRKGESLEEAAAEALRGTGKAILGSALTVAVAFLALSL--ARLP-SFKTLGVSCAVGVLVALLNAVTLT 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 482 PMLSSRIMRQQHGHAPGLFArlfnkmfgaVERGYAGVLRWSLRWPWTTVLIALLSLFGSCALVTRVPAEF--------LP 553
Cdd:TIGR00833 326 PALLTLEGREGLMKPGRKSK---------IRFIWRRLGTAVVRRPWPILVTTLIISGVSLLALPLIRTGYddekmiptDL 396
|
330 340
....*....|....*....|...
gi 2388338994 554 PEDQSQFAVNVELPTGTALEATI 576
Cdd:TIGR00833 397 ESVQGYEAADRHFPGNSMDPMVV 419
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
338-490 |
1.91e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 45.61 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 338 ILGAILTIVIILVFLhdIRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVVIENIYRHLEMGK 417
Cdd:PRK13024 273 IIGFALIFLFMLVYY--GLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGK 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 418 pRMRAALDATSEIGLAVI----ATTLsIVAV--FV----PVaymKGiigrfffqFGLTVSAAVLLSMLVSFTLTPMLSSR 487
Cdd:PRK13024 351 -SLKKAFKKGFKNAFSTIldsnITTL-IAAAilFFfgtgPV---KG--------FATTLIIGILASLFTAVFLTRLLLEL 417
|
...
gi 2388338994 488 IMR 490
Cdd:PRK13024 418 LVK 420
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
337-481 |
1.97e-04 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 44.97 E-value: 1.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 337 LILGAILTIVIILVFLHdiRATFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVVIENIYRHLEMG 416
Cdd:TIGR01129 254 GLIGLVLVLVFMILYYR--LFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLG 331
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2388338994 417 KPRMRAA----LDATSEIGLAVIATTLSIVAVFV----PVaymKGiigrfffqFGLTVSAAVLLSMLVSFTLT 481
Cdd:TIGR01129 332 KSVRQAIeagfERAFSTIFDANITTLIAALILYVfgtgPV---KG--------FAVTLAIGIIASLFTALVFT 393
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
255-484 |
2.65e-04 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 44.59 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 255 RDVAEVLDDVEDARSASFL---NGNSALALVVKKQSGANVVSL--AEQVREVLDEMRPDlerRGITAAVPTDNSVFVEHA 329
Cdd:pfam03176 61 GHVGSVQDFWGDPDTAALFvspDGKAAYVVVTLEGDPGTTEADesVAAVRDAVEQAPPP---EGLKAYLTGPAATVADLR 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 330 IGdVKFDLILGAILTIVIILVFLHDIRATFIAA----------LAIPTSIVATFAFMQYMGFSfNNISMLALSLSIGILV 399
Cdd:pfam03176 138 DA-GDRDLGLIEAVTLVVIFIILLIVYRSVVAAllplltvglsLGAAQGLVAILAHILGIGLS-TFALNLLVVLLIAVGT 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 400 DDAIVVIENIYRHLEMGKPRMRAALDATSEIGLAVIATTLSIVAVFVPVAYMKGiigRFFFQFGLTVSAAVLLSMLVSFT 479
Cdd:pfam03176 216 DYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARL---PVFAQVGPTIAIGVLVDVLAALT 292
|
....*
gi 2388338994 480 LTPML 484
Cdd:pfam03176 293 LLPAL 297
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
337-445 |
3.17e-04 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 45.04 E-value: 3.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 337 LILGAILTIVIILVFLHD-IRATFI-AALAIPTSIVAT---FAFMQYMGFSFNNISMLALSLSIGILVDDAIVVI---EN 408
Cdd:pfam02460 226 LLTFSIIVSVTLSSYTIDwVRSKPIlAALGLLSPVMAIvssFGLLFWMGFPFNSIVCVTPFLVLAIGVDDMFLMVaawQR 305
|
90 100 110
....*....|....*....|....*....|....*..
gi 2388338994 409 IYRHLEMgKPRMRAALdatSEIGLAVIATTLSIVAVF 445
Cdd:pfam02460 306 TTATLSV-KKRMGEAL---SEAGVSITITSLTDVLSF 338
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
331-588 |
5.25e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 44.07 E-value: 5.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 331 GDVKFDLILGAILTIVIILVFLHDIRATFIAALAIPTSIVATFAFMqymGFSFNNISMLALSLS---IGILVDDAIVVIE 407
Cdd:COG4258 249 HDISTIGLISLLGILLLLLLVFRSLRPLLLGLLPVAVGALAGLAAV---SLVFGSVHGITLGFGsslIGVAVDYSLHYLT 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 408 NIYRHLEMGKPRMRAALDATseIGLAVIATTLSIVA-VFVPVAYMKgiigrfffQFGLTVSAAVLLSMLVSFTLTPMLSS 486
Cdd:COG4258 326 HRRAAGEWDPRAALRRIWPT--LLLGLLTTVLGYLAlLFSPFPGLR--------QLGVFAAAGLLAAALTTLLWLPLLLP 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 487 RIMRQQHGHAPGLFARLFNKMFGAvergyagvLRWSLRWPwttVLIALLSLFGSCALVTR--------VPAEFLPPEDQ- 557
Cdd:COG4258 396 RAAPRPPAPALALLARLLARWPRR--------LRWLLALL---AVLALASLLGLNRLKWNddlralnpVPAALLAQEARl 464
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 2388338994 558 ---------SQFAVNvelpTGTALEATIETSEAVAADLRA 588
Cdd:COG4258 465 rallgapdvSQYLVV----YGPDAEQALQRNEALLPRLDA 500
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
806-973 |
1.84e-03 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 42.45 E-value: 1.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 806 VLVLAALNDVTLGEAQQIVTDAAKRVVPSKLQTSFMGDA----EVMQESFESMIFALALAIILVYMILAAQFDSLIQPIT 881
Cdd:COG2409 119 TVTLDGDAGDEAAEAVDALRDAVAAAPAPGLTVYVTGPAalaaDLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALL 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 882 IMVSLPLSVVGAFGGIYLAGMSLNIFSF---IGLIMLMGLVTKTAILLVDFANSEREKGAVITEALVQAgtirlrpiVMT 958
Cdd:COG2409 199 PLLTAGLAVGVALGLLALLAAFTDVSSFapnLLTMLGLGVGIDYALFLVSRYREELRAGEDREEAVARA--------VAT 270
|
170
....*....|....*..
gi 2388338994 959 AAATIF--GMIpVALAL 973
Cdd:COG2409 271 AGRAVLfsGLT-VAIAL 286
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
843-965 |
2.47e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 41.91 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 843 DAEVMQESFESMIFALALAIILVYMILAAQFDSLIQPITIMVSLPLSVVGAFGGIYLAGMSLNIFSFIGLIMLMGLVTKT 922
Cdd:TIGR03480 260 SDEELATVSEGATVAGLLSFVLVLVLLWLALRSPRLVFAVLVTLIVGLILTAAFATLAVGHLNLISVAFAVLFIGLGVDF 339
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2388338994 923 AILLVDFANSEREKGAVITEALVQAGTIRLRPIVMTAAATIFG 965
Cdd:TIGR03480 340 AIQFSLRYREERFRGGNHREALSVAARRMGAALLLAALATAAG 382
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
338-490 |
4.18e-03 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 40.87 E-value: 4.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 338 ILGAILTIVIILVFLHDIRatFIAALAIPTSIVATFAFMQYMGFSFNNISMLALSLSIGILVDDAIVVIENIYRHLEMGK 417
Cdd:COG0342 278 LIGLLLVALFMLLYYRLPG--LVANIALALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGR 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2388338994 418 PrMRAALDATSEIGLAVI----ATTLsIVAV--FV----PVaymKGiigrfffqFGLTVSAAVLLSMLVSFTLTPMLSSR 487
Cdd:COG0342 356 S-LRAAIEAGFKRAFSTIldanVTTL-IAAVvlFVlgtgPV---KG--------FAVTLILGILISMFTAVPVTRPLLNL 422
|
...
gi 2388338994 488 IMR 490
Cdd:COG0342 423 LLG 425
|
|
| |
