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Conserved domains on  [gi|2394495983|ref|WP_267888291|]
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tyrosine-protein phosphatase [Merdimmobilis hominis]

Protein Classification

tyrosine-protein phosphatase( domain architecture ID 11457164)

tyrosine-protein phosphatase catalyzes the dephosphorylation of O-phosphotyrosine groups in phosphoproteins

CATH:  3.90.190.10
EC:  3.1.3.48
Gene Ontology:  GO:0004721|GO:0004725
PubMed:  27514797|17057753
SCOP:  3000304

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Oca4 COG2365
Protein tyrosine/serine phosphatase Oca4 [Signal transduction mechanisms];
1-86 2.28e-20

Protein tyrosine/serine phosphatase Oca4 [Signal transduction mechanisms];


:

Pssm-ID: 441932 [Multi-domain]  Cd Length: 248  Bit Score: 81.16  E-value: 2.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2394495983   1 MLLSLAGVAKADIVADYQVSYTYIQPLIEAMRGDH--------PDLPAFIGRSNLEYMEAFLDRFQKTFGTVEEYLR-GI 71
Cdd:COG2365   153 LLLLALGVPRETIMADYLLTNEYLAPLRARLLAALraalgdedPELLAPLLGVRPEYLEAALDAIDERYGSVDAYLEeGL 232

                          90
                  ....*....|....*
gi 2394495983  72 GLTGEEIEALRAKLL 86
Cdd:COG2365   233 GLTDAELEALRARLL 247
 
Name Accession Description Interval E-value
Oca4 COG2365
Protein tyrosine/serine phosphatase Oca4 [Signal transduction mechanisms];
1-86 2.28e-20

Protein tyrosine/serine phosphatase Oca4 [Signal transduction mechanisms];


Pssm-ID: 441932 [Multi-domain]  Cd Length: 248  Bit Score: 81.16  E-value: 2.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2394495983   1 MLLSLAGVAKADIVADYQVSYTYIQPLIEAMRGDH--------PDLPAFIGRSNLEYMEAFLDRFQKTFGTVEEYLR-GI 71
Cdd:COG2365   153 LLLLALGVPRETIMADYLLTNEYLAPLRARLLAALraalgdedPELLAPLLGVRPEYLEAALDAIDERYGSVDAYLEeGL 232

                          90
                  ....*....|....*
gi 2394495983  72 GLTGEEIEALRAKLL 86
Cdd:COG2365   233 GLTDAELEALRARLL 247
Y_phosphatase3 pfam13350
Tyrosine phosphatase family; This family is closely related to the pfam00102 and pfam00782 ...
 1-86 8.43e-20

Tyrosine phosphatase family; This family is closely related to the pfam00102 and pfam00782 families.


Pssm-ID: 463853 [Multi-domain]  Cd Length: 243  Bit Score: 79.59  E-value: 8.43e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2394495983   1 MLLSLAGVAKADIVADYQVSYTYIQPLIEAMRGDHPD--LPAFIGRSNL-----EYMEAFLDRFQKTFGTVEEYLR-GIG 72
Cdd:pfam13350 149 LLLSLLGVPEDTIVADYLLTNEYLEPLRERLLAAFREelLDDAEGIRPLlsvrpEYLEAALDAIDERYGSVEGYLRdGLG 228

                          90
                  ....*....|....
gi 2394495983  73 LTGEEIEALRAKLL 86
Cdd:pfam13350 229 LSDEDIEALRARLL 242
 
Name Accession Description Interval E-value
Oca4 COG2365
Protein tyrosine/serine phosphatase Oca4 [Signal transduction mechanisms];
1-86 2.28e-20

Protein tyrosine/serine phosphatase Oca4 [Signal transduction mechanisms];


Pssm-ID: 441932 [Multi-domain]  Cd Length: 248  Bit Score: 81.16  E-value: 2.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2394495983   1 MLLSLAGVAKADIVADYQVSYTYIQPLIEAMRGDH--------PDLPAFIGRSNLEYMEAFLDRFQKTFGTVEEYLR-GI 71
Cdd:COG2365   153 LLLLALGVPRETIMADYLLTNEYLAPLRARLLAALraalgdedPELLAPLLGVRPEYLEAALDAIDERYGSVDAYLEeGL 232

                          90
                  ....*....|....*
gi 2394495983  72 GLTGEEIEALRAKLL 86
Cdd:COG2365   233 GLTDAELEALRARLL 247
Y_phosphatase3 pfam13350
Tyrosine phosphatase family; This family is closely related to the pfam00102 and pfam00782 ...
 1-86 8.43e-20

Tyrosine phosphatase family; This family is closely related to the pfam00102 and pfam00782 families.


Pssm-ID: 463853 [Multi-domain]  Cd Length: 243  Bit Score: 79.59  E-value: 8.43e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2394495983   1 MLLSLAGVAKADIVADYQVSYTYIQPLIEAMRGDHPD--LPAFIGRSNL-----EYMEAFLDRFQKTFGTVEEYLR-GIG 72
Cdd:pfam13350 149 LLLSLLGVPEDTIVADYLLTNEYLEPLRERLLAAFREelLDDAEGIRPLlsvrpEYLEAALDAIDERYGSVEGYLRdGLG 228

                          90
                  ....*....|....
gi 2394495983  73 LTGEEIEALRAKLL 86
Cdd:pfam13350 229 LSDEDIEALRARLL 242
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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