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Conserved domains on  [gi|2398820955|ref|WP_268093317|]
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cation transporter, partial [Enterobacter sp. JH602]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
fieF super family cl42912
CDF family cation-efflux pump FieF;
1-77 1.81e-46

CDF family cation-efflux pump FieF;


The actual alignment was detected with superfamily member PRK09509:

Pssm-ID: 181919 [Multi-domain]  Cd Length: 299  Bit Score: 149.44  E-value: 1.81e-46
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2398820955   1 MAAWTATCVATLLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:PRK09509   11 RAAIAATAMASLLLLIKIFAWWYTGSVSLLAALVDSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQS 87
 
Name Accession Description Interval E-value
fieF PRK09509
CDF family cation-efflux pump FieF;
1-77 1.81e-46

CDF family cation-efflux pump FieF;


Pssm-ID: 181919 [Multi-domain]  Cd Length: 299  Bit Score: 149.44  E-value: 1.81e-46
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2398820955   1 MAAWTATCVATLLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:PRK09509   11 RAAIAATAMASLLLLIKIFAWWYTGSVSLLAALVDSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQS 87
FieF COG0053
Divalent metal cation (Fe/Co/Zn/Cd) efflux pump [Inorganic ion transport and metabolism];
2-77 1.29e-24

Divalent metal cation (Fe/Co/Zn/Cd) efflux pump [Inorganic ion transport and metabolism];


Pssm-ID: 439823 [Multi-domain]  Cd Length: 284  Bit Score: 92.47  E-value: 1.29e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2398820955   2 AAWTATCVATLLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:COG0053     4 AALASLAANLLLAVLKLVAGLLTGSVALLADALHSLSDLVASLLVLLGLRLAAKPADEEHPYGHGKAEYLASLIVA 79
CDF TIGR01297
cation diffusion facilitator family transporter; This model describes a broadly distributed ...
12-77 1.27e-15

cation diffusion facilitator family transporter; This model describes a broadly distributed family of transporters, a number of which have been shown to transport divalent cations of cobalt, cadmium and/or zinc. The family has six predicted transmembrane domains. Members of the family are variable in length because of variably sized inserts, often containing low-complexity sequence. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273544 [Multi-domain]  Cd Length: 268  Bit Score: 68.40  E-value: 1.27e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2398820955  12 LLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:TIGR01297   1 LLMLIKIVGGLLSGSLALLADAIHSLSDVAASAIALLALRISRRPADERHPFGHGRAEILAALLNG 66
Cation_efflux pfam01545
Cation efflux family; Members of this family are integral membrane proteins, that are found to ...
12-77 3.31e-11

Cation efflux family; Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.


Pssm-ID: 426316 [Multi-domain]  Cd Length: 189  Bit Score: 55.74  E-value: 3.31e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2398820955  12 LLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:pfam01545   1 LLALVKLAAGLLTGSLALLADAVHSLIDLISSLLALLALRLSRKPPDERFPFGHGRLEPLAALVVG 66
 
Name Accession Description Interval E-value
fieF PRK09509
CDF family cation-efflux pump FieF;
1-77 1.81e-46

CDF family cation-efflux pump FieF;


Pssm-ID: 181919 [Multi-domain]  Cd Length: 299  Bit Score: 149.44  E-value: 1.81e-46
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2398820955   1 MAAWTATCVATLLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:PRK09509   11 RAAIAATAMASLLLLIKIFAWWYTGSVSLLAALVDSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQS 87
FieF COG0053
Divalent metal cation (Fe/Co/Zn/Cd) efflux pump [Inorganic ion transport and metabolism];
2-77 1.29e-24

Divalent metal cation (Fe/Co/Zn/Cd) efflux pump [Inorganic ion transport and metabolism];


Pssm-ID: 439823 [Multi-domain]  Cd Length: 284  Bit Score: 92.47  E-value: 1.29e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2398820955   2 AAWTATCVATLLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:COG0053     4 AALASLAANLLLAVLKLVAGLLTGSVALLADALHSLSDLVASLLVLLGLRLAAKPADEEHPYGHGKAEYLASLIVA 79
CDF TIGR01297
cation diffusion facilitator family transporter; This model describes a broadly distributed ...
12-77 1.27e-15

cation diffusion facilitator family transporter; This model describes a broadly distributed family of transporters, a number of which have been shown to transport divalent cations of cobalt, cadmium and/or zinc. The family has six predicted transmembrane domains. Members of the family are variable in length because of variably sized inserts, often containing low-complexity sequence. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273544 [Multi-domain]  Cd Length: 268  Bit Score: 68.40  E-value: 1.27e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2398820955  12 LLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:TIGR01297   1 LLMLIKIVGGLLSGSLALLADAIHSLSDVAASAIALLALRISRRPADERHPFGHGRAEILAALLNG 66
Cation_efflux pfam01545
Cation efflux family; Members of this family are integral membrane proteins, that are found to ...
12-77 3.31e-11

Cation efflux family; Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.


Pssm-ID: 426316 [Multi-domain]  Cd Length: 189  Bit Score: 55.74  E-value: 3.31e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2398820955  12 LLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:pfam01545   1 LLALVKLAAGLLTGSLALLADAVHSLIDLISSLLALLALRLSRKPPDERFPFGHGRLEPLAALVVG 66
CzcD COG1230
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism];
4-77 5.60e-06

Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism];


Pssm-ID: 440843 [Multi-domain]  Cd Length: 294  Bit Score: 42.03  E-value: 5.60e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2398820955   4 WTATCVATLLLIIKVAAWWVTGSVSLLAsliDS--ML-DIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:COG1230    21 LIALALTLGFMVVEIVGGLLSGSLALLA---DAghMLsDALALGLALFAYRLARRPADARFTFGYKRAEILAALANA 94
PRK03557 PRK03557
CDF family zinc transporter ZitB;
5-77 1.18e-04

CDF family zinc transporter ZitB;


Pssm-ID: 235130 [Multi-domain]  Cd Length: 312  Bit Score: 38.19  E-value: 1.18e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2398820955   5 TATCVATLLLIIKVAAWWVTGSVSLLASLIDSMLDIAASVVNLVVLRYSLQPADREHAFGHGKAESLAALAQA 77
Cdd:PRK03557   23 YAFGVTAGFMLVEVIGGFLSGSLALLADAGHMLTDAAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNA 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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