|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
212-436 |
1.80e-41 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 147.36 E-value: 1.80e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 212 DEQQRTKAALETARDFASVASHELRTPLTAMRTNLEVL-STLELPAKQRDEVLADVMRTQNRIEATLSALERLAQNQTIT 290
Cdd:COG2205 4 EALEELEELERLKSEFLANVSHELRTPLTSILGAAELLlDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESGK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 291 TD-DFVPVDIVELLDRAAHDAVRIYPDLMVSL---LPSPTVLMLGLPAGLRLAVDNAIANAVKHGHA-TRVQLSANSSRD 365
Cdd:COG2205 84 LSlELEPVDLAELLEEAVEELRPLAEEKGIRLeldLPPELPLVYADPELLEQVLANLLDNAIKYSPPgGTITISARREGD 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2415617109 366 GVEIAIDDDGTGVPEDERSSVFDRFSRGS-TASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:COG2205 164 GVRISVSDNGPGIPEEELERIFERFYRGDnSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLP 235
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
123-436 |
1.69e-39 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 144.67 E-value: 1.69e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 123 VALGAPLAGAERRIDQLHLRVLLICGSVIVGTFIVGSAMWLIMINPFRLLAQQARAINAQSNPGEVKVRGVWEAVEIAEA 202
Cdd:COG0642 9 VLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 203 VEGMLARIGDEQQRTKAALETARDFASVASHELRTPLTAMRTNLEVLSTlELPAKQRdEVLADVMRTQNRIEATLSALER 282
Cdd:COG0642 89 LLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLE-ELDEEQR-EYLETILRSADRLLRLINDLLD 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 283 LAQ-NQTITTDDFVPVDIVELLDRAAHDAVRIYPDLMVSL---LPSPTVLMLGLPAGLRLAVDNAIANAVKHGHA-TRVQ 357
Cdd:COG0642 167 LSRlEAGKLELEPEPVDLAELLEEVVELFRPLAEEKGIELeldLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEgGTVT 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 358 LSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQS-GSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:COG0642 247 VSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSRRGgGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLP 326
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
111-436 |
2.76e-39 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 145.85 E-value: 2.76e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 111 YRVRTFTAGPATVALGAPLAGAERRIDQLHLRVLLICGSVIVGTFIVGSAMWLIMINPFRLLAQQARAINAQSNPGEVKV 190
Cdd:COG5002 49 LLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 191 RGVWEAVEIAEAVEGMLARIGDEQQ---RTKAALETARDFASVASHELRTPLTAMRTNLEVL-STLELPAKQRDEVLADV 266
Cdd:COG5002 129 LLLGRLSLRLSALLLGLLLLAAVERditELERLEQMRREFVANVSHELRTPLTSIRGYLELLlDGAADDPEERREYLEII 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 267 MRTQNRIEATLSALERLAQNQTITTD-DFVPVDIVELLDRAAHDAVRIYPDLMVSL---LPSPTVLMLGLPAGLRLAVDN 342
Cdd:COG5002 209 LEEAERLSRLVNDLLDLSRLESGELKlEKEPVDLAELLEEVVEELRPLAEEKGIELeldLPEDPLLVLGDPDRLEQVLTN 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 343 AIANAVKHGHA-TRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTA---SQSGSGLGLALVAQQAVLHGGT 418
Cdd:COG5002 289 LLDNAIKYTPEgGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSrsrETGGTGLGLAIVKHIVEAHGGR 368
|
330
....*....|....*...
gi 2415617109 419 ASLHASPLGGARLLLKLP 436
Cdd:COG5002 369 IWVESEPGKGTTFTITLP 386
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
142-436 |
1.20e-27 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 114.56 E-value: 1.20e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 142 RVLLICGSVIVGTFIVGSAMWLIMINPFRLLAQQARAINAQsNPGEVKVRGVWEAVEIAEAVEGMLARIGDeqqrtKAAL 221
Cdd:PRK11100 183 RILWAGALLLGIALLIGAGVVWWLNRSIRRLTRYADAVTEG-KPVPLPKLGSSELRELAQALESMRVKLEG-----KAYV 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 222 EtarDFASVASHELRTPLTAMRTNLEVLSTlELPAKQRDEVLADVMRTQNRIEA---TLSALERLAQNQTIttDDFVPVD 298
Cdd:PRK11100 257 E---QYVQTLTHELKSPLAAIRGAAELLQE-DPPPEDRARFTGNILTQSARLQQlidRLLELARLEQRQEL--EVLEPVA 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 299 IVELLDR--AAHDAVRIYPDLMVSLLPSPTVlMLGLPAGLRLAVDNAIANAVKHGHA-TRVQLSANSSRDGVEIAIDDDG 375
Cdd:PRK11100 331 LAALLEElvEAREAQAAAKGITLRLRPDDAR-VLGDPFLLRQALGNLLDNAIDFSPEgGTITLSAEVDGEQVALSVEDQG 409
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2415617109 376 TGVPEDERSSVFDRF---SRGSTAsQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:PRK11100 410 PGIPDYALPRIFERFyslPRPANG-RKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLP 472
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
201-436 |
7.26e-26 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 109.25 E-value: 7.26e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 201 EAVEGMLARigdeQQRtkaaletardFASVASHELRTPLT--------AMRTNLEV--LSTLELPAKQRDEVLADVM--- 267
Cdd:PRK09470 234 TALERMMTS----QQR----------LLSDISHELRTPLTrlqlatalLRRRQGESkeLERIETEAQRLDSMINDLLvls 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 268 RTQNRieatlSALERlaqnqtittdDFVPVDIV--ELLDRAAHDAVRIYPDLMVSLLPSPTVLmLGLPAGLRLAVDNAIA 345
Cdd:PRK09470 300 RNQQK-----NHLER----------ETFKANSLwsEVLEDAKFEAEQMGKSLTVSAPPGPWPI-NGNPNALASALENIVR 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 346 NAVKHGHaTRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTA---SQSGSGLGLALVAQQAVLHGGTASLH 422
Cdd:PRK09470 364 NALRYSH-TKIEVAFSVDKDGLTITVDDDGPGVPEEEREQIFRPFYRVDEArdrESGGTGLGLAIVENAIQQHRGWVKAE 442
|
250
....*....|....
gi 2415617109 423 ASPLGGARLLLKLP 436
Cdd:PRK09470 443 DSPLGGLRLTIWLP 456
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
331-436 |
8.68e-24 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 95.41 E-value: 8.68e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 331 GLPAGLRLAVDNAIANAVKHGHA-TRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQ--SGSGLGLAL 407
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEgGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRkiGGTGLGLSI 80
|
90 100
....*....|....*....|....*....
gi 2415617109 408 VAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
5-436 |
9.52e-24 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 103.57 E-value: 9.52e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 5 SLRNIVIVAALSvIVLVIALGAWVWIGVTNDQY-NQLDR-RLDSVSSLGDVRTLLLSPPRSATDQS-VPADDSLVRTVRV 81
Cdd:NF040691 6 QLRVVAITLLLS-LVVILVLGVVLALQITNGLLdNRVDAaLGDSRRARTQAQSQLNASDASTSDSAqQLLRTTLLSVLAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 82 NNSTVSVPSDIVL---PALPIGYATTTING------VPYRVRTFTAG--------------------PATVA-------- 124
Cdd:NF040691 85 ASGAMQGAFDVVLlvpGDDPSGLGPRASGSvglvsqIPEELREAVAGgqvaqqyqsvalpsgdgssaPALVVgtpvtlpv 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 125 -------LGAPLAGAERRIDQLHlRVLLICGSVIVGtfIVGSAMWLI---MINPFRLLAQQARAINAQSNPGEVKVRGVW 194
Cdd:NF040691 165 agnyelyLLFPLEDEQSTLALVR-GTLLLGGLALVV--LLGLIAWLVtrqVVAPVRSAARTAERFAAGDLSERMPVKGED 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 195 EAVEIAEAVEGMLARIgdeqQRTKAALET----ARDFASVASHELRTPLTAMRTNLEVL--STLELPAKQRDEvlADVMR 268
Cdd:NF040691 242 DLARLARSFNQMADSL----QRQIRQLEElsrlQQRFVSDVSHELRTPLTTIRMAADVIhdSRDDFDPATARS--AELLH 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 269 TQ-NRIEATLSALERL----AQNQTITTDdfvPVDIVELLDRAAHDAVRIYPDLMVSL---LPSPTVLMLGLPAGLRLAV 340
Cdd:NF040691 316 TElDRFESLLSDLLEIsrfdAGAAELDVE---PVDLRPLVRRVVDALRQLAERAGVELrvdAPGTPVVAEVDPRRVERVL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 341 DNAIANAVKHGHATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQ---SGSGLGLALVAQQAVLHGG 417
Cdd:NF040691 393 RNLVVNAIEHGEGKPVVVTVAQDDTAVAVTVRDHGVGLKPGEVALVFDRFWRADPARArttGGTGLGLAIALEDARLHGG 472
|
490
....*....|....*....
gi 2415617109 418 TASLHASPLGGARLLLKLP 436
Cdd:NF040691 473 WLEAWGRPGQGSQFRLTLP 491
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
120-436 |
9.78e-24 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 103.24 E-value: 9.78e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 120 PATVALGAPLAGAERRIDQLHLRVLLIcgsVIVGTFIVGSAMWLIM---INPFRLLAQQARAINAQS---------NPGE 187
Cdd:TIGR01386 143 PVQITVALDINAHTHLLDALRKWLILI---AVLLVLLTALLGWWITrlgLEPLRRLSAVAARISPESldqrldpsrAPAE 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 188 VKvrgvweavEIAEAVEGMLARIGDEQQRTKaaletarDFASVASHELRTPLTAMRTNLEVLSTLELPAKQRDEVLADVM 267
Cdd:TIGR01386 220 LR--------ELAQSFNAMLGRLEDAFQRLS-------QFSADLAHELRTPLTNLLGQTQVALSQPRTGEEYREVLESNL 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 268 RTQNRIEATLSALERLAQ-NQTITTDDFVPVDIVELLDRAAHDAVRIYPDLMVSLLPSPTVLMLGLPAGLRLAVDNAIAN 346
Cdd:TIGR01386 285 EELERLSRMVSDMLFLARaDNGQLALERVRLDLAAELAKVAEYFEPLAEERGVRIRVEGEGLVRGDPQMFRRAISNLLSN 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 347 AVKHGHA-TRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTA---SQSGSGLGLALVAQQAVLHGGTASLh 422
Cdd:TIGR01386 365 ALRHTPDgGTITVRIERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPArsnSGEGTGLGLAIVRSIMEAHGGRASA- 443
|
330
....*....|....
gi 2415617109 423 ASPLGGARLLLKLP 436
Cdd:TIGR01386 444 ESPDGKTRFILRFP 457
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
232-436 |
1.28e-23 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 102.37 E-value: 1.28e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 232 SHELRTPLTAMRTNLEV---LSTLELPAKQRD----EVLADVMRTQNRieatlsaLERlaQNQTITTddfVPVDIVELLD 304
Cdd:PRK10604 220 AHELRTPLVRLRYRLEMsdnLSAAESQALNRDigqlEALIEELLTYAR-------LDR--PQNELHL---SEPDLPAWLS 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 305 RAAHDAVRIYPDLMVSLLPSPTVLMLGLpaGLRL---AVDNAIANAVKHGHaTRVQLSANSSRDGVEIAIDDDGTGVPED 381
Cdd:PRK10604 288 THLADIQAVTPEKTVRLDTPHQGDYGAL--DMRLmerVLDNLLNNALRYAH-SRVRVSLLLDGNQACLIVEDDGPGIPPE 364
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2415617109 382 ERSSVFDRFSR---GSTASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:PRK10604 365 ERERVFEPFVRldpSRDRATGGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWP 422
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
133-436 |
1.55e-23 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 102.94 E-value: 1.55e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 133 ERRIDQLHLRVLLICGSVIVGTFIVGSAMWLIMINPFRLLAQQARAINAQSNPGEVKVRGVWEAVEIAEAVEGMLARIGD 212
Cdd:COG4251 187 VLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEE 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 213 EQQRTKAALETA----RDFASVASHELRTPLTAMRTNLEVLSTlELPAKQRDEVLADVMRTQN---RIEATLSALERLAQ 285
Cdd:COG4251 267 ELEERTAELERSneelEQFAYVASHDLREPLRKISGFSQLLEE-DYGDKLDEEGREYLERIRDaaeRMQALIDDLLAYSR 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 286 NQTiTTDDFVPVDIVELLDRAAHD-AVRIYP-DLMVSLLPSPTVLmlGLPAGLRLAVDNAIANAVKH---GHATRVQLSA 360
Cdd:COG4251 346 VGR-QELEFEPVDLNELLEEVLEDlEPRIEErGAEIEVGPLPTVR--GDPTLLRQVFQNLISNAIKYsrpGEPPRIEIGA 422
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2415617109 361 NSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQ-SGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:COG4251 423 EREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEyEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTLP 499
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
331-436 |
1.61e-22 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 92.05 E-value: 1.61e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 331 GLPAGLRLAVDNAIANAVKH-GHATRVQLSAnSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQSGSGLGLALVA 409
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHaAKAGEITVTL-SEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGGGGTGLGLSIVR 79
|
90 100
....*....|....*....|....*..
gi 2415617109 410 QQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:pfam02518 80 KLVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
336-435 |
1.75e-22 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 91.51 E-value: 1.75e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 336 LRLAVDNAIANAVKHGHA-TRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQS-GSGLGLALVAQQAV 413
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPgGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSREGgGTGLGLAIVRRIVE 80
|
90 100
....*....|....*....|..
gi 2415617109 414 LHGGTASLHASPLGGARLLLKL 435
Cdd:cd00075 81 AHGGRITVESEPGGGTTFTVTL 102
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
210-436 |
1.13e-21 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 96.57 E-value: 1.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 210 IGDEQQRTKaaLETARDFASVASHELRTPLTAMRTNLEVL-----STLELPAKQRDEVLADVMRTQNRIEATLSALERLA 284
Cdd:COG5000 189 ITELLRAER--LAAWGELARRIAHEIKNPLTPIQLSAERLrrklaDKLEEDREDLERALDTIIRQVDRLKRIVDEFLDFA 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 285 QnqtITTDDFVPVDIVELLDRAAH--DAVRIYPDLMVSL-LPSPTVLMLGLPAGLRLAVDNAIANAVKHGHAT-RVQLSA 360
Cdd:COG5000 267 R---LPEPQLEPVDLNELLREVLAlyEPALKEKDIRLELdLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGgEIEVST 343
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2415617109 361 NSSRDGVEIAIDDDGTGVPEDERSSVFDRFSrgsTASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:COG5000 344 RREDGRVRIEVSDNGPGIPEEVLERIFEPFF---TTKPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLP 416
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
91-436 |
3.92e-20 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 91.40 E-value: 3.92e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 91 DIVLPALPIGYATTTINGVPYRVRTFTAGPATVALGAPLAGAERRIDQLHLRVLLICGSVIVGTFIVGSAMWLIMINPFR 170
Cdd:COG4191 3 RLLLLLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 171 LLAQQARAINAQSNPGEVKVRGVWEAVEIAEAVEGMLARIGDEQQRTKAALETARDFASV------ASHELRTPLTAMRT 244
Cdd:COG4191 83 GLLLLLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRELQEQLVQSEKLAALgelaagIAHEINNPLAAILG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 245 NLEVLSTL---ELPAKQRDEVLADVMRTQNRIEATLSALERLAQNQTittDDFVPVDIVELLDRAAHDAVRIYPDLMVSL 321
Cdd:COG4191 163 NAELLRRRledEPDPEELREALERILEGAERAAEIVRSLRAFSRRDE---EEREPVDLNELIDEALELLRPRLKARGIEV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 322 ---LPSPTVLMLGLPAGLRLAVDNAIAN---AVKHGHATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSrgST 395
Cdd:COG4191 240 eldLPPDLPPVLGDPGQLEQVLLNLLINaidAMEEGEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFF--TT 317
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 2415617109 396 -ASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:COG4191 318 kPVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLP 359
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
207-436 |
5.48e-20 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 91.81 E-value: 5.48e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 207 LARIGDEQQRTKaaletaRDFASVASHELRTPLTAMRTNLEVLSTLELPAKQrdEVLADVMRTQNRIEATLSALERLAQN 286
Cdd:NF012163 229 LASTLEKNEQMR------RDFMADISHELRTPLAVLRAELEAIQDGIRKFTP--ESLDSLQAEVGTLTKLVDDLHDLSMS 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 287 QTITTD-DFVPVDIVELLdRAAHDAVRIY-----PDLMVSLLPSPTVlmLGLPAGLRLAVDNAIANAVKHGHA-TRVQLS 359
Cdd:NF012163 301 DEGALAyQKASVDLVPLL-EVEGGAFRERfasagLELEVSLPDSSLV--FGDRDRLMQLFNNLLENSLRYTDSgGSLHIS 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 360 ANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSR---GSTASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:NF012163 378 ASQRPKEVTLTVADSAPGVSDEQLARLFERFYRvevSRNRASGGSGLGLAISLNIVQAHGGTLHAAHSPLGGLRIVVTLP 457
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
161-428 |
7.05e-20 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 91.63 E-value: 7.05e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 161 MWLIM--INPFRLLAQQAR--------AINAQSNPGEVKvrgvweavEIAEAVEGMLARIGDEQQRTkaaletaRDFASV 230
Cdd:PRK10337 179 MVLLGreLAPLKKLALALRmrdpdsetPLNATGVPSEVR--------PLVEALNQLFARTHAMMVRE-------RRFTSD 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 231 ASHELRTPLTAMRTNLEVLSTLELPAKQRDEVLADVMRTQNRIEA------TLSALERLAQnqtitTDDFVPVDIVELLD 304
Cdd:PRK10337 244 AAHELRSPLAALKVQTEVAQLSDDDPQARKKALLQLHAGIDRATRlvdqllTLSRLDSLDN-----LQDVAEIPLEDLLQ 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 305 RAAHDavrIYP-----DLMVSL-LPSPTVLMLGLPAGLRLAVDNAIANAVKHGHA-TRVQLSANSSRdgveIAIDDDGTG 377
Cdd:PRK10337 319 SAVMD---IYHtaqqaGIDVRLtLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQgSVVDVTLNARN----FTVRDNGPG 391
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 2415617109 378 VPEDERSSVFDRFSRGSTASQSGSGLGLALVAQQAVLHGGTASLHASPLGG 428
Cdd:PRK10337 392 VTPEALARIGERFYRPPGQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEGG 442
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-436 |
2.66e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 82.86 E-value: 2.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 336 LRLAVDNAIANAVKHGHaTRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSR---GSTASQSGSGLGLALVAQQA 412
Cdd:cd16939 1 MARALDNLLRNALRYAH-RTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRldpSRDRATGGFGLGLAIVHRVA 79
|
90 100
....*....|....*....|....
gi 2415617109 413 VLHGGTASLHASPLGGARLLLKLP 436
Cdd:cd16939 80 LWHGGHVECDDSELGGACFRLTWP 103
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
225-408 |
3.57e-19 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 88.03 E-value: 3.57e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 225 RDFASVASHELRTPLTAMRTNLEVL--STLELPAKQR---DEVLADVMRTQNRIEA--TLSALERLAQNqtittDDFVPV 297
Cdd:TIGR02966 115 RDFVANVSHELRTPLTVLRGYLETLadGPDEDPEEWNralEIMLEQSQRMQSLVEDllTLSRLESAASP-----LEDEPV 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 298 DIVELLDRAAHDAVRI--YPDLMVSLLPSPTVLMLGLPAGLRLAVDNAIANAVKHGHA-TRVQLSANSSRDGVEIAIDDD 374
Cdd:TIGR02966 190 DMPALLDHLRDEAEALsqGKNHQITFEIDGGVDVLGDEDELRSAFSNLVSNAIKYTPEgGTITVRWRRDGGGAEFSVTDT 269
|
170 180 190
....*....|....*....|....*....|....*..
gi 2415617109 375 GTGVPEDERSSVFDRFSRGSTA---SQSGSGLGLALV 408
Cdd:TIGR02966 270 GIGIAPEHLPRLTERFYRVDKSrsrDTGGTGLGLAIV 306
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
212-444 |
6.28e-19 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 87.59 E-value: 6.28e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 212 DEQQRTKAALETARDFASVASHELRTPLTAMRTNLEVLStLELPAKQRDEvLADVMRTQ-NRIEATLSALERLAQNQTIt 290
Cdd:COG3852 123 ERELRRAEKLAAVGELAAGLAHEIRNPLTGIRGAAQLLE-RELPDDELRE-YTQLIIEEaDRLNNLVDRLLSFSRPRPP- 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 291 tdDFVPVDIVELLDRA-------AHDAVRIYPDLMVSLlpsPTVLmlGLPAGLRLAVDNAIANAV----KHGH------- 352
Cdd:COG3852 200 --EREPVNLHEVLERVlellraeAPKNIRIVRDYDPSL---PEVL--GDPDQLIQVLLNLVRNAAeampEGGTitirtrv 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 353 ATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFsrgSTASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLL 432
Cdd:COG3852 273 ERQVTLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPF---FTTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFR 349
|
250
....*....|..
gi 2415617109 433 LKLPGPRPHNED 444
Cdd:COG3852 350 IYLPLEQAEEEP 361
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-436 |
2.14e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 80.06 E-value: 2.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 339 AVDNAIANAVKHGHATrVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQS---GSGLGLALVAQQAVLH 415
Cdd:cd16949 4 ALENVLRNALRYSPSK-ILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDResgGTGLGLAIAERAIEQH 82
|
90 100
....*....|....*....|.
gi 2415617109 416 GGTASLHASPLGGARLLLKLP 436
Cdd:cd16949 83 GGKIKASNRKPGGLRVRIWLP 103
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
149-436 |
3.42e-18 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 86.50 E-value: 3.42e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 149 SVIVGTFIVGSAMWLIMI--NPFRLLAQQARAINAQSNPGEVKVRGVWEAVEIAEAVEGMLARIGD-EQQRtkaALETAR 225
Cdd:PRK09467 159 TLAIGLLSVAGGWLFIRIqnRPLVALEHAALQVGKGEIPPPLREYGASEVRSVTRAFNQMAAGIKQlEDDR---TLLMAG 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 226 dfasvASHELRTPLTAMRTNLEVLStlelpakQRDEVLADVMrtQNRIE---ATLSA-LERLAQNQTittDDFVPVDIVE 301
Cdd:PRK09467 236 -----VSHDLRTPLTRIRLATEMMS-------EEDGYLAESI--NKDIEecnAIIEQfIDYLRTGQE---MPMEMADLNA 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 302 LLDRAAHDAVRIYPDLMVSLLPSPtVLMLGLPAGLRLAVDNAIANAVKHGHAtRVQLSANSSRDGVEIAIDDDGTGVPED 381
Cdd:PRK09467 299 LLGEVIAAESGYEREIETALQPGP-IEVPMNPIAIKRALANLVVNAARYGNG-WIKVSSGTEGKRAWFQVEDDGPGIPPE 376
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2415617109 382 ERSSVFDRFSRGSTA-SQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:PRK09467 377 QLKHLFQPFTRGDSArGSSGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLP 432
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-436 |
1.59e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 77.89 E-value: 1.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 336 LRLAVDNAIANAVKHGHAT-RVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTA---SQSGSGLGLALVAQQ 411
Cdd:cd16946 5 LQQLFVNLLENSLRYTDTGgKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSrnrASGGSGLGLAICHNI 84
|
90 100
....*....|....*....|....*
gi 2415617109 412 AVLHGGTASLHASPLGGARLLLKLP 436
Cdd:cd16946 85 ALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
312-430 |
1.33e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 76.13 E-value: 1.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 312 RIYPD--LMVSLLPSPTVLMLGLPAGLRLAVDNAIANAVKHGHAtRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDR 389
Cdd:cd16954 12 KVYQRkgVSISLDISPELRFPGERNDLMELLGNLLDNACKWCLE-FVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQR 90
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2415617109 390 FSRGSTASQsGSGLGLALVAQQAVLHGGTASLHASPLGGAR 430
Cdd:cd16954 91 GQRLDEQRP-GQGLGLAIAKEIVEQYGGELSLSDSPLGGAR 130
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
340-436 |
5.31e-16 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 73.68 E-value: 5.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 340 VDNAIANAVK---HGHATRVQLSAnSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQ---SGSGLGLALVAQQAV 413
Cdd:cd16925 9 VLNLLSNAFKftpDGGRIRCILEK-FRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTrahGGTGLGLSIVKEFVE 87
|
90 100
....*....|....*....|...
gi 2415617109 414 LHGGTASLHASPLGGARLLLKLP 436
Cdd:cd16925 88 LHGGTVTVSDAPGGGALFQVELP 110
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
206-415 |
5.50e-16 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 79.67 E-value: 5.50e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 206 MLARigDEQQrtKAALETARD--FASVaSHELRTPLTAMRTNLEVLSTLELPAKQRDEVLAdVMRTQ-NRIEA------T 276
Cdd:PRK11006 189 MVAR--DVTQ--MHQLEGARRnfFANV-SHELRTPLTVLQGYLEMMQDQPLEGALREKALH-TMREQtQRMEGlvkqllT 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 277 LSALERLAqnqTITTDDFVPV-DIVELLDRAA-------HDAV-RIYPDLMVsllpsptvlmLGLPAGLRLAVDNAIANA 347
Cdd:PRK11006 263 LSKIEAAP---TIDLNEKVDVpMMLRVLEREAqtlsqgkHTITfEVDNSLKV----------FGNEDQLRSAISNLVYNA 329
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2415617109 348 VKHGHA-TRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQS---GSGLGLALVaQQAVLH 415
Cdd:PRK11006 330 VNHTPEgTHITVRWQRVPQGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRqtgGSGLGLAIV-KHALSH 400
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
96-440 |
9.52e-16 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 79.69 E-value: 9.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 96 ALPIGYATTTINGVPYRVRTFTAGPATVALGAplagaerrIDQLHLRVLLIcgsvivgtfivgsamwliminpfrllAQQ 175
Cdd:PRK10490 582 GQPAGAGTDTLPGVPYQILPLKSAQKTYGLLA--------VEPGNLRQLMI--------------------------PEQ 627
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 176 ARAINAQsnpgevkvrgvweAVEIAEAVEGM-LARiGDEQQRTKAALETARD-FASVASHELRTPLTAMRTNLEVLsTLE 253
Cdd:PRK10490 628 QRLLETF-------------TLLIANALERLtLTA-SEEQARLASEREQLRNaLLAALSHDLRTPLTVLFGQAEIL-TLD 692
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 254 LPAKQRDEVL-ADVMRTQnrieaTLSALeRLAQN----QTITTDDFVPVDIVELLDRAAHDAVRIypdLMVSLLPSPtvL 328
Cdd:PRK10490 693 LASEGSPHARqASEIRQQ-----VLNTT-RLVNNlldmARIQSGGFNLRKEWLTLEEVVGSALQM---LEPGLSGHP--I 761
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 329 MLGLPAGLRLA-VD---------NAIANAVKH-GHATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTAS 397
Cdd:PRK10490 762 NLSLPEPLTLIhVDgplfervliNLLENAVKYaGAQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFARGNKES 841
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 2415617109 398 Q-SGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLPGPRP 440
Cdd:PRK10490 842 AiPGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLPLETP 885
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-435 |
1.67e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 72.44 E-value: 1.67e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 336 LRLAVDNAIANAVKH-GHATRVQLsANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQSGSGLGLALVAQQAVL 414
Cdd:cd16940 14 LFLLLRNLVDNAVRYsPQGSRVEI-KLSADDGAVIRVEDNGPGIDEEELEALFERFYRSDGQNYGGSGLGLSIVKRIVEL 92
|
90 100
....*....|....*....|.
gi 2415617109 415 HGGTASLHASPLGGARLLLKL 435
Cdd:cd16940 93 HGGQIFLGNAQGGGLEAWVRL 113
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
213-440 |
3.28e-14 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 74.94 E-value: 3.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 213 EQQRTKAALETARD----FASVASHELRTPLTAMRTNLEVLSTLELPAKQRDEVLAdVMRTQNRIEATL------SALER 282
Cdd:PRK11466 429 EHRQARAEAEKASQaksaFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRA-ITDSGESLLTILndildySAIEA 507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 283 LAQNQTITTDDFVPVDIVELLDRAAHDAVRIYPDLMVSLLPS--PTVLMlGLPAGLRLAVDNAIANAVKHGHATRVQLSA 360
Cdd:PRK11466 508 GGKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATDIADdlPTALM-GDPRRIRQVITNLLSNALRFTDEGSIVLRS 586
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 361 NSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGStASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLPGPRP 440
Cdd:PRK11466 587 RTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVS-GKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVA 665
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
206-436 |
1.33e-13 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 72.50 E-value: 1.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 206 MLARIGDEQQRTKaaletarDFASVASHELRTPLTAMRTNLEVLSTLELPAKQRDEVLADVMRTQNRIEATLSALERLAQ 285
Cdd:PRK09835 251 MIERIEDVFTRQS-------NFSADIAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQ 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 286 ---NQTITtdDFVPVDIvelldraaHDAVRIYPDLMVSLLPSPTV---------LMLGLPAGLRLAVDNAIANAVKH--- 350
Cdd:PRK09835 324 adnNQLIP--EKKMLDL--------ADEVGKVFDFFEAWAEERGVelrfvgdpcQVAGDPLMLRRAISNLLSNALRYtpa 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 351 GHATRVQLSanSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQ---SGSGLGLALVAQQAVLHGGTASLhASPLG 427
Cdd:PRK09835 394 GEAITVRCQ--EVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDPSRQrkgEGSGIGLAIVKSIVVAHKGTVAV-TSDAR 470
|
....*....
gi 2415617109 428 GARLLLKLP 436
Cdd:PRK09835 471 GTRFVISLP 479
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
225-436 |
2.01e-13 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 71.97 E-value: 2.01e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 225 RDFASVASHELRTPLTAMRTNLEVL------STLELPAKQRDEV-----LADVMRtqnriEATLSALERLAQNQTittdd 293
Cdd:PRK10549 241 RDFMADISHELRTPLAVLRGELEAIqdgvrkFTPESVASLQAEVgtltkLVDDLH-----QLSLSDEGALAYRKT----- 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 294 fvPVDIVELLDRAAHDAVRIYPDLMVSL---LPsPTVLMLGLPAGLRLAVDNAIANAVKHGHAT-RVQLSANSSRDGVEI 369
Cdd:PRK10549 311 --PVDLVPLLEVAGGAFRERFASRGLTLqlsLP-DSATVFGDPDRLMQLFNNLLENSLRYTDSGgSLHISAEQRDKTLRL 387
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 370 AIDDDGTGVPEDERSSVFDRFSR--GSTASQSG-SGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:PRK10549 388 TFADSAPGVSDEQLQKLFERFYRteGSRNRASGgSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELP 457
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
215-436 |
4.70e-13 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 71.21 E-value: 4.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 215 QRTKAaLETARDFASVA-----------SHELRTPLTAMRTNLEVLSTLELPAKQRDevLADVMRtqnriEATLSALE-- 281
Cdd:PRK15347 379 ERTQA-LAEAKQRAEQAnkrksehlttiSHEIRTPLNGVLGALELLQNTPLTAEQMD--LADTAR-----QCTLSLLAii 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 282 -RLAQNQTITTDDFV----PVDIVELLDRAAH--DAVRIYPDLMVSLLPSPTVLMLGLPAGLRLA--VDNAIANAVKHGH 352
Cdd:PRK15347 451 nNLLDFSRIESGQMTlsleETALLPLLDQAMLtiQGPAQSKSLTLRTFVGAHVPLYLHLDSLRLRqiLVNLLGNAVKFTE 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 353 ATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQsGSGLGLALVAQQAVLHGGTASLHASPLGGARLL 432
Cdd:PRK15347 531 TGGIRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQADTHSQ-GTGLGLTIASSLAKMMGGELTLFSTPGVGSCFS 609
|
....
gi 2415617109 433 LKLP 436
Cdd:PRK15347 610 LVLP 613
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
340-436 |
7.88e-13 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 69.49 E-value: 7.88e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 340 VDNAIaNAVKHGHAT--RVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRfsrG-STASQSGSGLGLALVAQQAVLHG 416
Cdd:COG3290 290 LDNAI-EAVEKLPEEerRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFER---GfSTKLGEGRGLGLALVKQIVEKYG 365
|
90 100
....*....|....*....|
gi 2415617109 417 GTASLHASPLGGARLLLKLP 436
Cdd:COG3290 366 GTIEVESEEGEGTVFTVRLP 385
|
|
| marine_sort_HK |
TIGR03785 |
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is ... |
225-436 |
1.38e-12 |
|
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is paired with an adjacent response regulator (TIGR03787) gene. It co-occurs with a variant sortase enzyme (TIGR03784), usually in the same gene neighborhood, in proteobacterial species most of which are marine, and with an LPXTG motif-containing sortase target conserved protein (TIGR03788). Sortases and LPXTG proteins are far more common in Gram-positive bacteria, where sortase systems mediate attachment to the cell wall or cross-linking of pilin structures. We give this predicted sensor histidine kinase the gene symbol psdS, for Proteobacterial Dedicated Sortase system Sensor histidine kinase.
Pssm-ID: 163497 [Multi-domain] Cd Length: 703 Bit Score: 69.77 E-value: 1.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 225 RDFASVASHELRTPLTAMRTNLEVLSTLELPakQRDEVLADVMRTQ----NRIEATLSALERLaqNQTITTDDFVPVDIV 300
Cdd:TIGR03785 486 ENMSSRLSHELRTPVAVVRSSLENLELQALE--QEKQKYLERAREGterlSMILNNMSEATRL--EQAIQSAEVEDFDLS 561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 301 ELLDRAAHDAVRIYPDLMVSL-LPSPTVLMLGLPAGLRLAVDNAIANAV---KHGHATRVQLSANSSRdgVEIAIDDDGT 376
Cdd:TIGR03785 562 EVLSGCMQGYQMTYPPQRFELnIPETPLVMRGSPELIAQMLDKLVDNARefsPEDGLIEVGLSQNKSH--ALLTVSNEGP 639
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2415617109 377 GVPEDERSSVFDRF--SRGSTA-SQSGSGLGLALVAQQAVLHGG--TASLHASPlGGARLLLKLP 436
Cdd:TIGR03785 640 PLPEDMGEQLFDSMvsVRDQGAqDQPHLGLGLYIVRLIADFHQGriQAENRQQN-DGVVFRISLP 703
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
342-436 |
2.30e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 63.28 E-value: 2.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 342 NAIANAVK---HGHAT-RVQLSANS-SRDGVEIAIDDDGTGVPEDERSSVFDRFSR--GSTASQ-SGSGLGLALVAQQAV 413
Cdd:cd16922 7 NLLGNAIKfteEGEVTlRVSLEEEEeDGVQLRFSVEDTGIGIPEEQQARLFEPFSQadSSTTRKyGGTGLGLAISKKLVE 86
|
90 100
....*....|....*....|...
gi 2415617109 414 LHGGTASLHASPLGGARLLLKLP 436
Cdd:cd16922 87 LMGGDISVESEPGQGSTFTFTLP 109
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
232-431 |
2.33e-12 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 68.51 E-value: 2.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 232 SHELRTPLTAMRTNLEVLSTlelpAKQRDEVLAD-VMRTQ-NRIEATLSA-LER--LAQNQTITTDDFVPVDIveLLDR- 305
Cdd:PRK10815 274 THSLKTPLAVLQSTLRSLRS----GKQMSVEQAEpIMLEQiSRISQQIGYyLHRasMRSEHNLLSRELHSVAP--LLDNl 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 306 -AAHDAVRIYPDLMVSLLPSPTVLMLGLPAGLRLAVDNAIANAVKHGhATRVQLSANSSRDGVEIAIDDDGTGVPEDERS 384
Cdd:PRK10815 348 tSALNKVYQRKGVNITLDISPEITFVGEKNDFMEVMGNVLDNACKYC-LEFVEISARQTDEHLHIVVEDDGPGIPESKRE 426
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2415617109 385 SVFDRFSRGSTAsQSGSGLGLALVAQQAVLHGGTASLHASPLGGARL 431
Cdd:PRK10815 427 LIFDRGQRADTL-RPGQGLGLSVAREITEQYEGKISAGDSPLGGARM 472
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-436 |
5.54e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 62.08 E-value: 5.54e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 336 LRLAVDNAIANAVKHGHATrVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTA-SQSGSGLGLALVAQQAVL 414
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGW-VEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNArGTSGTGLGLAIVQRISDA 79
|
90 100
....*....|....*....|..
gi 2415617109 415 HGGTASLHASPLGGARLLLKLP 436
Cdd:cd16950 80 HGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
340-436 |
6.56e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 61.92 E-value: 6.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 340 VDNAI-ANAVKHGHATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRfsrG-STASQSGSGLGLALVAQQAVLHGG 417
Cdd:cd16915 9 IDNALdALAATGAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFER---GvSTKGQGERGIGLALVRQSVERLGG 85
|
90
....*....|....*....
gi 2415617109 418 TASLHASPLGGARLLLKLP 436
Cdd:cd16915 86 SITVESEPGGGTTFSIRIP 104
|
|
| TMAO_torS |
TIGR02956 |
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the ... |
200-439 |
7.54e-12 |
|
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems]
Pssm-ID: 274362 [Multi-domain] Cd Length: 968 Bit Score: 67.50 E-value: 7.54e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 200 AEAVEGMLAR-IGDEQQRTKAAletardFASVASHELRTPLTAMRTNLEVLSTLELPAKQRDEvLADVMRTQNRIEATL- 277
Cdd:TIGR02956 445 AEVKNHAKARaEAEEANRAKSA------FLATMSHEIRTPLNGILGTLELLGDTGLTSQQQQY-LQVINRSGESLLDILn 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 278 -----SALErlAQNQTITTDDFvpvDIVELLDRAAHdavriypdLMVSLLPSPTVLM------------LGLPAGLRLAV 340
Cdd:TIGR02956 518 dildySKIE--AGHLSISPRPF---DLNALLDDVHH--------LMVSRAQLKGIQLrlnipeqlpnwwQGDGPRIRQVL 584
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 341 DNAIANAVKHGH--ATRVQLSANSSRDgVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQS-GSGLGLALVAQQAVLHGG 417
Cdd:TIGR02956 585 INLVGNAIKFTDrgSVVLRVSLNDDSS-LLFEVEDTGCGIAEEEQATLFDAFTQADGRRRSgGTGLGLAISQRLVEAMDG 663
|
250 260
....*....|....*....|..
gi 2415617109 418 TASLHASPLGGARLLLKLPGPR 439
Cdd:TIGR02956 664 ELGVESELGVGSCFWFTLPLTR 685
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-422 |
1.87e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 60.48 E-value: 1.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 336 LRLAVDNAIANAVKHG-HATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQS-GSGLGLALVAQQAV 413
Cdd:cd16923 1 LQRVFSNLLSNAIKYSpENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTeGAGLGLSIAKAIIE 80
|
....*....
gi 2415617109 414 LHGGTASLH 422
Cdd:cd16923 81 LHGGSASAE 89
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
213-436 |
2.21e-11 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 66.30 E-value: 2.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 213 EQQRTKA--ALETARDFASVASHELRTPLTAMRTNLEVLSTLELPAKQRDEVLADVMRTQnriEATLSALERLAQNQTIT 290
Cdd:PRK09959 699 EVERNKAinATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATG---QSLLGLIGEILDVDKIE 775
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 291 TDDF--VP--VDIVELLDRAAHDAVRIYPDLMVSLLPSPTV----LMLGLPAGLRLAVDNAIANAVKHGHATRVQLSA-- 360
Cdd:PRK09959 776 SGNYqlQPqwVDIPTLVQNTCHSFGAIAASKSIALSCSSTFpdhyLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTsl 855
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 361 ---NSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTA-SQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:PRK09959 856 ghiDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGrQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIP 935
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
213-418 |
2.74e-11 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 65.54 E-value: 2.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 213 EQQRtkaaletaRDFASVASHELRTPLTAMRTNLEVLSTLELpakqRDEVLA----DVmrTQN------RIEATLSALER 282
Cdd:NF033092 369 EQER--------REFVANVSHELRTPLTTMRSYLEALADGAW----KDPELAprflGV--TQNetermiRLVNDLLQLSR 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 283 L-AQNQTITTDDfvpVDIVELLDRAA--HDA-------------------VRIYPDLMVSLLpsptvlmlglpaglrlav 340
Cdd:NF033092 435 MdSKDYKLNKEW---VNFNEFFNYIIdrFEMilknknitfkrefpkrdlwVEIDTDKITQVL------------------ 493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 341 DNAIANAVKH---GHATRVQLSANSSRdgVEIAIDDDGTGVPEDERSSVFDRFSRGSTA---SQSGSGLGLAlVAQQAV- 413
Cdd:NF033092 494 DNIISNAIKYspeGGTITFRLLETHNR--IIISISDQGLGIPKKDLDKIFDRFYRVDKArsrKMGGTGLGLA-IAKEVVe 570
|
....*
gi 2415617109 414 LHGGT 418
Cdd:NF033092 571 AHGGR 575
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
333-435 |
7.11e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 59.01 E-value: 7.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 333 PAGLRLAVDNAIANAVKHGHAT-RVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRF---SRGSTASQSgSGLGLALV 408
Cdd:cd16945 2 PFLLRQAINNLLDNAIDFSPEGgLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFyslPRPHSGQKS-TGLGLAFV 80
|
90 100
....*....|....*....|....*..
gi 2415617109 409 AQQAVLHGGTASLHASPlGGARLLLKL 435
Cdd:cd16945 81 QEVAQLHGGRITLRNRP-DGVLAFLTL 106
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
239-436 |
1.06e-10 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 61.94 E-value: 1.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 239 LTAMRTNLEVLStlELPAKQRDEVLADVMRTQNRIEATLSALERLAQNqtITTDDFVPVDIVELLDRAAHDAVRIYpDLM 318
Cdd:COG4585 69 LSAIKLQLEAAR--RLLDADPEAAREELEEIRELAREALAELRRLVRG--LRPPALDDLGLAAALEELAERLLRAA-GIR 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 319 VSLLPSPTVLmlGLPAGLRLA----VDNAIANAVKHGHATRVQLSANSSRDGVEIAIDDDGTGVPEDERssvfdrfsrgs 394
Cdd:COG4585 144 VELDVDGDPD--RLPPEVELAlyriVQEALTNALKHAGATRVTVTLEVDDGELTLTVRDDGVGFDPEAA----------- 210
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2415617109 395 tasqSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:COG4585 211 ----PGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLP 248
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
215-436 |
1.45e-10 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 62.29 E-value: 1.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 215 QRTKAALETARDFASVASHELRTPLTAMRTNLEVLSTLELPakQRDEVLADVMRTQNRIEATLSaLERLAQN------QT 288
Cdd:PRK10755 128 SRLTSTLDQERLFTADVAHELRTPLAGIRLHLELLEKQHHI--DVAPLIARLDQMMHTVEQLLQ-LARAGQSfssghyQT 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 289 IT-TDDFVPVDIVELLDRAAHDAVRIypdlmvsLLPSPT--VLMLGLPAGLRLAVDNAIANAVKHG-HATRVQLSANSSR 364
Cdd:PRK10755 205 VKlLEDVILPSQDELSEMLEQRQQTL-------LLPESAadITVQGDATLLRLLLRNLVENAHRYSpEGSTITIKLSQED 277
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2415617109 365 DGVEIAIDDDGTGVPEDERSSVFDRFSRGSTaSQSGSGLGLALVAQQAVLHGGTASLH-ASPLGGARLLLKLP 436
Cdd:PRK10755 278 GGAVLAVEDEGPGIDESKCGELSKAFVRMDS-RYGGIGLGLSIVSRITQLHHGQFFLQnRQERSGTRAWVWLP 349
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
225-288 |
4.68e-10 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 55.26 E-value: 4.68e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2415617109 225 RDFASVASHELRTPLTAMRTNLEVLSTLELPAKQRdEVLADVMRTQNRIEATLSALERLAQNQT 288
Cdd:smart00388 3 REFLANLSHELRTPLTAIRGYLELLLDTELSEEQR-EYLETILREAERLLRLINDLLDLSRIEA 65
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
227-418 |
7.29e-10 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 60.76 E-value: 7.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 227 FASVASHELRTPLTAMRTNLEVLstLELPAKQRDEVLaDVMRTQ-NRIEATLSALERLAQNQTIttdDFVPVDI------ 299
Cdd:COG5809 273 LAAGIAHEIRNPLTSLKGFIQLL--KDTIDEEQKTYL-DIMLSElDRIESIISEFLVLAKPQAI---KYEPKDLntliee 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 300 -VELLD-RAAHDAVRIYPDLMvsllpSPTVLMLGLPAGLRLAVDNAIANAV----KHGHATrVQLSAnSSRDGVEIAIDD 373
Cdd:COG5809 347 vIPLLQpQALLKNVQIELELE-----DDIPDILGDENQLKQVFINLLKNAIeampEGGNIT-IETKA-EDDDKVVISVTD 419
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2415617109 374 DGTGVPEDERSSVFDRFSrgSTASQsGSGLGLALVAQQAVLHGGT 418
Cdd:COG5809 420 EGCGIPEERLKKLGEPFY--TTKEK-GTGLGLMVSYKIIEEHGGK 461
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
225-288 |
1.78e-09 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 53.75 E-value: 1.78e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2415617109 225 RDFASVASHELRTPLTAMRTNLEVLSTLELPAKQRdEVLADVMRTQNRIEATLSALERLAQNQT 288
Cdd:pfam00512 3 SEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQR-EYLETILRSAERLLRLINDLLDLSRIEA 65
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
340-436 |
4.94e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 53.73 E-value: 4.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 340 VDNAIANAVKHG--HATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQS---GSGLGLALVAQQAVL 414
Cdd:cd16953 5 LRNLIGNAISFSppDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAfgqHSGLGLSISRQIIEA 84
|
90 100
....*....|....*....|....*.
gi 2415617109 415 HGG--TASLHASP--LGGARLLLKLP 436
Cdd:cd16953 85 HGGisVAENHNQPgqVIGARFTVQLP 110
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
228-418 |
5.02e-09 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 58.20 E-value: 5.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 228 ASVAsHELRTPLTAMRTNLEVLStlelPAKQRDEVLADVMRTQ-NRIEATLSALERLAQNQtitTDDFVPVDIVELLDRA 306
Cdd:COG5805 292 AGIA-HEIRNPLTSIKGFLQLLQ----PGIEDKEEYFDIMLSElDRIESIISEFLALAKPQ---AVNKEKENINELIQDV 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 307 A----HDAvrIYPDLMVSLLPSPTVL-MLGLPAGLRLAVDNAIANAVK---HGhaTRVQLSANSSRDGVEIAIDDDGTGV 378
Cdd:COG5805 364 VtlleTEA--ILHNIQIRLELLDEDPfIYCDENQIKQVFINLIKNAIEampNG--GTITIHTEEEDNSVIIRVIDEGIGI 439
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2415617109 379 PEDERSSVFDRFsrgSTASQSGSGLGLALVAQQAVLHGGT 418
Cdd:COG5805 440 PEERLKKLGEPF---FTTKEKGTGLGLMVSYKIIENHNGT 476
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
221-285 |
7.05e-09 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 51.83 E-value: 7.05e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2415617109 221 LETARDFASVASHELRTPLTAMRTNLEVLSTLELPAKQRDEVLADVMRTQNRIEATLSALERLAQ 285
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
233-417 |
8.18e-09 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 57.27 E-value: 8.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 233 HELRTPLTAMRTNLEvlsTLELPAKQRD--------EVLADVMRTQNRIEATLSA---------------------LERL 283
Cdd:PRK09303 160 HDLRTPLTAASLALE---TLELGQIDEDtelkpaliEQLQDQARRQLEEIERLITdllevgrtrwealrfnpqkldLGSL 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 284 AQ-------------NQTITTDdfVPVDIvelldraahDAVRIYPDLM----VSLLpsptvlmlglpaglrlavDNAIAN 346
Cdd:PRK09303 237 CQevilelekrwlakSLEIQTD--IPSDL---------PSVYADQERIrqvlLNLL------------------DNAIKY 287
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2415617109 347 AVKHGHATRVQLSANSSRdgVEIAIDDDGTGVPEDERSSVF-DRFSRGSTASQSGSGLGLALVAQQAVLHGG 417
Cdd:PRK09303 288 TPEGGTITLSMLHRTTQK--VQVSICDTGPGIPEEEQERIFeDRVRLPRDEGTEGYGIGLSVCRRIVRVHYG 357
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-436 |
9.78e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 52.71 E-value: 9.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 336 LRLAVDNAIANAVKHGHATRV-QLSANSSRDGVE--IAIDDDGTGVPEDERSSVFDRFSRGSTASQS-GSGLGLALVAQQ 411
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPpRIEVGAEDVGEEwtFYVRDNGIGIDPEYAEKVFGIFQRLHSREEYeGTGVGLAIVRKI 80
|
90 100
....*....|....*....|....*
gi 2415617109 412 AVLHGGTASLHASPLGGARLLLKLP 436
Cdd:cd16921 81 IERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
228-436 |
1.50e-08 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 56.72 E-value: 1.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 228 ASVAsHELRTPLTAMRtNLEVLSTLELPAKQRDEVLADVMRTQ-NRIEATLSALERLAQNQTITtddFVPVDIVELLDRA 306
Cdd:PRK10364 242 AGVA-HEIRNPLSSIK-GLAKYFAERAPAGGEAHQLAQVMAKEaDRLNRVVSELLELVKPTHLA---LQAVDLNDLINHS 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 307 ----AHDAVRiyPDLMVSLLPSPTVLMLGL-PAGLRLAVDNAIANAVKH-GHATRVQLSANSSRDGVEIAIDDDGTGVPE 380
Cdd:PRK10364 317 lqlvSQDANS--REIQLRFTANDTLPEIQAdPDRLTQVLLNLYLNAIQAiGQHGVISVTASESGAGVKISVTDSGKGIAA 394
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2415617109 381 DERSSVFDRFSrgsTASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:PRK10364 395 DQLEAIFTPYF---TTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLP 447
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
342-436 |
1.65e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 52.01 E-value: 1.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 342 NAIaNAVKHGHATRVQLSANSSRDG---VEIAIDDDGTGVPEDERSSVFDRFsrgSTASQSGSGLGLALVAQQAVLHGGT 418
Cdd:cd16920 11 NGI-EAMSEGGCERRELTIRTSPADdraVTISVKDTGPGIAEEVAGQLFDPF---YTTKSEGLGMGLSICRSIIEAHGGR 86
|
90
....*....|....*...
gi 2415617109 419 ASLHASPLGGARLLLKLP 436
Cdd:cd16920 87 LSVESPAGGGATFQFTLP 104
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
3-436 |
5.98e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 54.64 E-value: 5.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 3 VVSLRNIVIVAALSVIVLVIALGAWVWIGVTNDQYNQLDRRLDSVSSLGDVRTLLLSPPRSATDQSVPADDSLVRTVRVN 82
Cdd:COG2972 18 LLLVLLILLLSLLLIILLLLLLLILLLLLLILLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLILLLLLLLLLLLILLL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 83 NSTVSVPSDIVLPALPIGYATTTINGVPYRVRTFTAGPA-TVALGAPLAGAERRIDQLHLRVLLICGSVIVGTFIVGSAM 161
Cdd:COG2972 98 SLLLLLALILLLALLLLLSILLLILGLLLIILLLLSLLGwTLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 162 WLIMINPFRLLAQQARAInAQSNPGEVKVRGVWEAVEIAEAVEGMLARIGDEQQRTKAaLETARdfasvasHELRtpLTA 241
Cdd:COG2972 178 SRSITRPIKRLKKAMKKV-EKGDLVRLEVSGNDEIGILARSFNEMVERIKELIEEVYE-LELEK-------KEAE--LKA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 242 MRT--------N-LEVLSTLelpAKQRDevladvmrtQNRIEATLSALERLAQNQTITTDDFVPVDI-VELLD------- 304
Cdd:COG2972 247 LQAqinphflfNtLNSIRWL---AELED---------PEEAEEMLEALSKLLRYSLSKGDELVTLEEeLELIKsyleiqk 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 305 -RAAHD---AVRIYPDLMVSLLPSptvLMLG-LpaglrlaVDNAIanavKHG-----HATRVQLSANSSRDGVEIAIDDD 374
Cdd:COG2972 315 lRFGDRlevEIEIDEELLDLLIPK---LILQpL-------VENAI----EHGiepkeGGGTIRISIRKEGDRLVITVEDN 380
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2415617109 375 GTGVPEDERSSVFDRFSRGStasqSGSGLGLALVAQQ-AVLHGGTASLHAS--PLGGARLLLKLP 436
Cdd:COG2972 381 GVGMPEEKLEKLLEELSSKG----EGRGIGLRNVRERlKLYYGEEYGLEIEsePGEGTTVTIRIP 441
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
355-436 |
1.58e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 49.46 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 355 RVQLSANSSRDgVEIAIDDDGTGVPEDERSSVFDRFSrgsTASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLK 434
Cdd:cd16944 31 RIRVEADQDGR-IVLIVCDNGKGFPREMRHRATEPYV---TTRPKGTGLGLAIVKKIMEEHGGRISLSNREAGGACIRII 106
|
..
gi 2415617109 435 LP 436
Cdd:cd16944 107 LP 108
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
228-436 |
1.86e-07 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 53.43 E-value: 1.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 228 ASVAsHELRTPLTAMRTNLEVL-STLELPAKQR--DEVLADVMRTqNRIEATLSALERLAQNQtittddFVPVDIVELLD 304
Cdd:PRK11360 395 AGVA-HEIRNPLTAIRGYVQIWrQQTSDPPSQEylSVVLREVDRL-NKVIDQLLEFSRPRESQ------WQPVSLNALVE 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 305 RA------AHDAVRIypDLMVSLLPS-PTVLMLglPAGLRLAVDNAIANAVKHGHAT-RVQLSANSSRDG-VEIAIDDDG 375
Cdd:PRK11360 467 EVlqlfqtAGVQARV--DFETELDNElPPIWAD--PELLKQVLLNILINAVQAISARgKIRIRTWQYSDGqVAVSIEDNG 542
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2415617109 376 TGVPEDERSSVFDRFsrgSTASQSGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:PRK11360 543 CGIDPELLKKIFDPF---FTTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLP 600
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
213-443 |
1.96e-07 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 53.41 E-value: 1.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 213 EQQRTKAALETA-RD---FASVASHELRTPLTAMRTNLEVLSTLELPAKQRDEvladvMRTQNRIEATL----------S 278
Cdd:PRK11091 268 ERKRYQDALEKAsRDkttFISTISHELRTPLNGIVGLSRILLDTELTAEQRKY-----LKTIHVSAITLgnifndiidmD 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 279 ALER----LAqNQTITTDDFVpVDIVELLDRAAHDAvriypDL---MVSLLPSPTVLMLGlPAGLRLAVDNAIANAVKHG 351
Cdd:PRK11091 343 KMERrklqLD-NQPIDFTDFL-ADLENLSGLQAEQK-----GLrfdLEPLLPLPHKVITD-GTRLRQILWNLISNAVKFT 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 352 HATRVQLSANSS-RDGVEIAIDDDGTGVPEDERSSVFDRF----SRGSTASQSGSGLGLALVAQQAVLHGGTASLHASPL 426
Cdd:PRK11091 415 QQGGVTVRVRYEeGDMLTFEVEDSGIGIPEDELDKIFAMYyqvkDSHGGKPATGTGIGLAVSKRLAQAMGGDITVTSEEG 494
|
250
....*....|....*..
gi 2415617109 427 GGARLLLKLPGPRPHNE 443
Cdd:PRK11091 495 KGSCFTLTIHAPAVAEE 511
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-439 |
5.74e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 47.97 E-value: 5.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 336 LRLAVDNAIANAVKH---GHATRVQLSANSSrdGVEIAIDDDGTGVPEDERSSVFDRFSRGSTA---SQSGSGLGLALVA 409
Cdd:cd16952 1 LRSAFSNLVSNAVKYtppSDTITVRWSQEES--GARLSVEDTGPGIPPEHIPRLTERFYRVDIErcrNTGGTGLGLAIVK 78
|
90 100 110
....*....|....*....|....*....|
gi 2415617109 410 QQAVLHGGTASLHASPLGGARLLLKLPGPR 439
Cdd:cd16952 79 HVMSRHDARLLIASELGKGSRFTCLFPSSR 108
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-434 |
6.18e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 47.84 E-value: 6.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 339 AVDNAIANAVKHGHATR-VQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQSGS--GLGLALVAQQAVLH 415
Cdd:cd16975 8 ALINIISNACQYAPEGGtVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGhyGMGLYIAKNLVEKH 87
|
90
....*....|....*....
gi 2415617109 416 GGTASLHASPLGGARLLLK 434
Cdd:cd16975 88 GGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
333-436 |
1.04e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 47.03 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 333 PAGLRLAVDNAIANAVkhgHAT----RVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRgSTASQSGSGLGLALV 408
Cdd:cd16943 1 PSQLNQVLLNLLVNAA---QAMegrgRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFT-TKPVGEGTGLGLSLS 76
|
90 100
....*....|....*....|....*...
gi 2415617109 409 AQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:cd16943 77 YRIIQKHGGTIRVASVPGGGTRFTIILP 104
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
340-425 |
1.06e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 47.01 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 340 VDNAiANAVKHGHA-----TRVQ----LSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSrgsTASQSGSGLGLALVAQ 410
Cdd:cd16918 9 VRNA-AQALAGSGGeiilrTRTQrqvtLGHPRHRLALRVSVIDNGPGIPPDLQDTIFYPMV---SGRENGTGLGLAIAQN 84
|
90
....*....|....*
gi 2415617109 411 QAVLHGGTASLHASP 425
Cdd:cd16918 85 IVSQHGGVIECDSQP 99
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
340-435 |
1.20e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 46.68 E-value: 1.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 340 VDNAiANAVKHGHATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFsrgSTASQSGSGLGLALVAQQAVL--HGG 417
Cdd:cd16976 9 LQNA-LDAMGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPF---FTTKPVGKGTGLGLSISYGIVeeHGG 84
|
90
....*....|....*...
gi 2415617109 418 TASLHASPLGGARLLLKL 435
Cdd:cd16976 85 RLSVANEEGAGARFTFDL 102
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
208-407 |
1.62e-06 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 50.74 E-value: 1.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 208 ARIGDEQ--QRTKAALETARD----FASVASHELRTPLTAMRTNLEVLSTLELPAkqrdEVLADVMRTQN---------- 271
Cdd:PRK10841 425 ARVKMEEslQEMAQAAEQASQsksmFLATVSHELRTPLYGIIGNLDLLQTKELPK----GVDRLVTAMNNssslllkiis 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 272 ------RIEAtlsalERLaqnqTITTDDFVPVDIVelldraAHdAVRIYPDLMVS--------LLPSPTVLMLGLPAGLR 337
Cdd:PRK10841 501 dildfsKIES-----EQL----KIEPREFSPREVI------NH-ITANYLPLVVKkrlglycfIEPDVPVALNGDPMRLQ 564
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2415617109 338 LAVDNAIANAVKHGHATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQS---GSGLGLAL 407
Cdd:PRK10841 565 QVISNLLSNAIKFTDTGCIVLHVRVDGDYLSFRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRnfqGTGLGLAI 637
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
343-436 |
1.98e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 45.62 E-value: 1.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 343 AIANAVKHGHATRVQLSANSSRDGVEIAIDDDGTGVPEDERSsvfdrfsrgstasqSGSGLGLALVAQQAVLHGGTASLH 422
Cdd:cd16917 8 ALTNALKHAGASRVRVTLSYTADELTLTVVDDGVGFDGPAPP--------------GGGGFGLLGMRERAELLGGTLTIG 73
|
90
....*....|....
gi 2415617109 423 ASPLGGARLLLKLP 436
Cdd:cd16917 74 SRPGGGTRVTARLP 87
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
342-425 |
2.45e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 46.35 E-value: 2.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 342 NAIANAVKHGHATRVqLSANSSRDGVEIAID--DDGTGVPEDERSSVFDRF-----SRGStaSQSGSGLGLALVAQQAVL 414
Cdd:cd16947 27 NLISNAIKYGSDGKF-LGMTLREDEKHVYIDiwDKGKGISETEKDHVFERLytledSRNS--AKQGNGLGLTITKRLAES 103
|
90
....*....|.
gi 2415617109 415 HGGTASLHASP 425
Cdd:cd16947 104 MGGSIYVNSKP 114
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
336-410 |
4.24e-06 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 44.95 E-value: 4.24e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2415617109 336 LRLAVDNAIANAVKHGHA----TRVQLSANSSRDGVEIAIDDDGTGVPEderssvfdRFSRGSTASQSGSGLGLALVAQ 410
Cdd:cd16936 1 VELAVSEAVTNAVRHAYRhdgpGPVRLELDLDPDRLRVEVTDSGPGFDP--------LRPADPDAGLREGGRGLALIRA 71
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
336-410 |
4.93e-06 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 45.67 E-value: 4.93e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2415617109 336 LRLAVDNAIANAVKHGHA----TRVQLSANSSRDGVEIAIDDDGTGVPEDERssvfdrfsRGSTASQSGSGLGLALVAQ 410
Cdd:COG2172 35 LVLAVSEAVTNAVRHAYGgdpdGPVEVELELDPDGLEIEVRDEGPGFDPEDL--------PDPYSTLAEGGRGLFLIRR 105
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
199-436 |
1.07e-05 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 47.75 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 199 IAEAVEgmLARIGDEQQRTKAALETAR------DFASVASHELRTPLTAMRTNLEVLSTLELPAKQRDEVLADVMRTQNR 272
Cdd:PRK13837 421 LAHAIE--RRRLETERDALERRLEHARrleavgTLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGAR 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 273 ----IEATLSALERLAQNQTittddfvPVDIVELLDRAAhdavriyPDLMVSLLPSPT---------VLMLGLPAGLRLA 339
Cdd:PRK13837 499 arliIDQILAFGRKGERNTK-------PFDLSELVTEIA-------PLLRVSLPPGVEldfdqdqepAVVEGNPAELQQV 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 340 VDNAIANAV---KHGHATRVQLSANSSR-------------DGVEIAIDDDGTGVPEDERSSVFDRFSrgsTASQSGSGL 403
Cdd:PRK13837 565 LMNLCSNAAqamDGAGRVDISLSRAKLRapkvlshgvlppgRYVLLRVSDTGAGIDEAVLPHIFEPFF---TTRAGGTGL 641
|
250 260 270
....*....|....*....|....*....|...
gi 2415617109 404 GLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:PRK13837 642 GLATVHGIVSAHAGYIDVQSTVGRGTRFDVYLP 674
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
260-436 |
3.85e-05 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 46.05 E-value: 3.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 260 DEVLADVMRTQNRIEATLSALERLAQnqtitTDDFVPVDIVELLDRAAHDAVRIYPDLMVSL--------LPSPTVLMLG 331
Cdd:COG3920 327 PEAREALEESQNRIQALALVHELLYQ-----SEDWEGVDLRDYLRELLEPLRDSYGGRGIRIeldgpdveLPADAAVPLG 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 332 LpaglrlAVDNAIANAVKHGHAT----RVQLSANSSRDGVEIAIDDDGTGVPEDerssvfdrfsrgsTASQSGSGLGLAL 407
Cdd:COG3920 402 L------ILNELVTNALKHAFLSgeggRIRVSWRREDGRLRLTVSDNGVGLPED-------------VDPPARKGLGLRL 462
|
170 180
....*....|....*....|....*....
gi 2415617109 408 VAQQAVLHGGTASLHASPlgGARLLLKLP 436
Cdd:COG3920 463 IRALVRQLGGTLELDRPE--GTRVRITFP 489
|
|
| UhpB |
COG3851 |
Signal transduction histidine kinase UhpB, glucose-6-phosphate specific [Signal transduction ... |
337-443 |
5.45e-05 |
|
Signal transduction histidine kinase UhpB, glucose-6-phosphate specific [Signal transduction mechanisms];
Pssm-ID: 443060 [Multi-domain] Cd Length: 493 Bit Score: 45.38 E-value: 5.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 337 RLAVDnAIANAVKHGHATRVQLSANSSRDGVEIAIDDDGTGVPEDERSsvfdrfsrgstasqsgSGLGLALVAQQAVLHG 416
Cdd:COG3851 403 RLVQE-ALTNILKHAEASQIRISLSQDKRLLSLEIRDDGIGLPPELRA----------------KGFGLRGMRERVRALG 465
|
90 100
....*....|....*....|....*..
gi 2415617109 417 GTASLHASPlGGARLLLKLPGPRPHNE 443
Cdd:COG3851 466 GDFRLSSAP-KGTRLSVLLPTPAASNE 491
|
|
| HATPase_c_2 |
pfam13581 |
Histidine kinase-like ATPase domain; |
336-410 |
1.16e-04 |
|
Histidine kinase-like ATPase domain;
Pssm-ID: 433327 [Multi-domain] Cd Length: 127 Bit Score: 41.89 E-value: 1.16e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2415617109 336 LRLAVDNAIANAVKHGH----ATRVQLSANSSRDGVEIAIDDDGTGVPEDERssvFDRFSRGSTASQSGSGLGLALVAQ 410
Cdd:pfam13581 32 VELAVGEACTNAVEHAYregpEGPVEVRLTSDGGGLVVTVADSGPPFDPLTL---PPPDLEEPDEDRKEGGRGLALIRG 107
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
221-436 |
1.22e-04 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 44.09 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 221 LETARDFASVASHELRTPLTAMRTNLEVLSTLELPAKQRDE----VLADVMRTQNRIEATLSalerLAQNQtitTDDFVP 296
Cdd:COG5806 198 LEVVSELAASIAHEVRNPLTVVRGFIQLLQEPELSDEKRKQyiriALEELDRAEAIITDYLT----FAKPQ---PEKLEK 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 297 VDIVELLDR--------AAHDAVRIYPDLmvsllpSPTVLMLGLPAGLRLAVDNAIANAVKhghAT----RVQLSANSSR 364
Cdd:COG5806 271 IDVSEELEHvidvlspyANMNNVEIQTEL------EPGLYIEGDRQKLQQCLINIIKNGIE---AMpnggTLTIDVSIDK 341
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2415617109 365 DGVEIAIDDDGTGVPEDERSsvfdRFsrGS---TASQSGSGLGLaLVAQQAV-LHGGTASLHASPLGGARLLLKLP 436
Cdd:COG5806 342 NKVIISIKDTGVGMTKEQLE----RL--GEpyfSTKEKGTGLGT-MVSYRIIeAMNGTIRVESEVGKGTTFTITLP 410
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
338-384 |
2.12e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 41.25 E-value: 2.12e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 2415617109 338 LAVDNAIANAVKHGHATR----VQLSANSSRDGVEIAIDDDGTGVPEDERS 384
Cdd:cd16951 42 LVVNELLQNALKHAFSDReggtITIRSVVDGDYLRITVIDDGVGLPQDEDW 92
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-408 |
3.22e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 39.96 E-value: 3.22e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2415617109 336 LRLAVDNAIANAVKH-GHATRVQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTA--SQSGSGLGLALV 408
Cdd:cd16948 6 LSFIIGQIVSNALKYsKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGrnFQESTGMGLYLV 81
|
|
| LytS |
COG3275 |
Sensor histidine kinase, LytS/YehU family [Signal transduction mechanisms]; |
346-436 |
4.27e-04 |
|
Sensor histidine kinase, LytS/YehU family [Signal transduction mechanisms];
Pssm-ID: 442506 [Multi-domain] Cd Length: 352 Bit Score: 42.16 E-value: 4.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 346 NAVKHG-----HATRVQLSANSSRDGVEIAIDDDGTGVPEDerssvfdrfsrgstASQSGSGLGLALVAQQ-AVLHGGTA 419
Cdd:COG3275 264 NAIKHGisskeGGGTISISIEVEGDRLVIEVENNGVGIQPK--------------KKKKGSGIGLKNVRERlELLYGDKY 329
|
90
....*....|....*....
gi 2415617109 420 SLH--ASPLGGARLLLKLP 436
Cdd:COG3275 330 SLEieSTDGGGTKVTLKIP 348
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
367-436 |
5.36e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 39.67 E-value: 5.36e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2415617109 367 VEIAIDDDGTGVPEDERSSVFDRFSrgSTASQ-SGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:cd16919 48 VCLEVSDTGSGMPAEVLRRAFEPFF--TTKEVgKGTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_LytS-like |
cd16957 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
333-436 |
1.31e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis LytS and Staphylococcus aureus LytS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and a GAF sensor domain; most contain a DUF3816 domain.
Pssm-ID: 340433 [Multi-domain] Cd Length: 106 Bit Score: 38.18 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 333 PAGLRLAVDNAIanavKHGHATR-----VQLSANSSRDGVEIAIDDDGTGVPEDERssvfDRFSRGSTASQSGSGLGLAL 407
Cdd:cd16957 3 PFALQVLVENAI----RHAFPKRkenneVRVVVKKDQHKVHVSVSDNGQGIPEERL----DLLGKTTVTSEKGTGTALEN 74
|
90 100 110
....*....|....*....|....*....|..
gi 2415617109 408 VAQQ-AVLHGGTASLHASPL--GGARLLLKLP 436
Cdd:cd16957 75 LNRRlIGLFGSEACLHIESEvhGGTEVWFVIP 106
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
332-443 |
1.61e-03 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 40.97 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 332 LPAGL---RLA------VDNAIANAVKHGHATR-VQLSANSSRDGVEIAIDDDGTGVPEDERSSVFDRFSRGSTASQSGS 401
Cdd:PRK15053 424 LPPGLdstEFAaivgnlLDNAFEASLRSDEGNKiVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEH 503
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2415617109 402 GLGLALVAQQAVLHGGTASLHASPLGGARLLLKLPGPRPHNE 443
Cdd:PRK15053 504 GIGLYLIASYVTRCGGVITLEDNDPCGTLFSIFIPKVKPNDS 545
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
367-436 |
1.86e-03 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 40.42 E-value: 1.86e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 367 VEIAIDDDGTGVPEDERSSVFDRFSRGSTASQsGSGLGLALVAQQAVLHGGTASLHASPLGGARLLLKLP 436
Cdd:PRK13557 325 VSIAVTDTGSGMPPEILARVMDPFFTTKEEGK-GTGLGLSMVYGFAKQSGGAVRIYSEVGEGTTVRLYFP 393
|
|
| HATPase_c_3 |
pfam13589 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ... |
340-405 |
3.00e-03 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain] Cd Length: 135 Bit Score: 37.70 E-value: 3.00e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2415617109 340 VDNAIAnavkhGHATRVQLSANSSRDGV-EIAIDDDGTGVPEDERSSVFdRFSRGSTASQSGS------GLGL 405
Cdd:pfam13589 9 IDNSID-----ADATNIKIEVNKNRGGGtEIVIEDDGHGMSPEELINAL-RLATSAKEAKRGStdlgryGIGL 75
|
|
| PRK11644 |
PRK11644 |
signal transduction histidine-protein kinase/phosphatase UhpB; |
343-436 |
4.89e-03 |
|
signal transduction histidine-protein kinase/phosphatase UhpB;
Pssm-ID: 236945 [Multi-domain] Cd Length: 495 Bit Score: 39.19 E-value: 4.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2415617109 343 AIANAVKHGHATRVQLSANSSRDGVEIAIDDDGTGVPEDerssvfdrfsrgstasQSGSGLGLALVAQQAVLHGGTASLH 422
Cdd:PRK11644 418 GLNNIVKHADASAVTLQGWQQDERLMLVIEDDGSGLPPG----------------SGQQGFGLRGMRERVTALGGTLTIS 481
|
90
....*....|....
gi 2415617109 423 ASPlgGARLLLKLP 436
Cdd:PRK11644 482 CTH--GTRLSVSLP 493
|
|
| |
