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Conserved domains on  [gi|2482172056|ref|WP_277996530|]
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MULTISPECIES: hypothetical protein [Bacillus cereus group]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Terminase_3 super family cl45920
Phage terminase large subunit; Initiation of packaging of double-stranded viral DNA involves ...
17-95 1.78e-13

Phage terminase large subunit; Initiation of packaging of double-stranded viral DNA involves the specific interaction of the prohead with viral DNA in a process mediated by a phage-encoded terminase protein. The terminase enzymes are usually hetero-oligomers composed of a small and a large subunit. This region is found on the large subunit and possess an endonuclease and ATPase activity that require Mg2+ and a neutral or slightly basic reaction. This region is also found in bacterial sequences.


The actual alignment was detected with superfamily member TIGR01547:

Pssm-ID: 459265 [Multi-domain]  Cd Length: 394  Bit Score: 64.35  E-value: 1.78e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482172056  17 LNSPAPNHPV----ISEVFDVQNTRWTHWTPNDNPILSEQRKQEIHEVFPKNPYLLERDWYGKRVMPQ-GVIYSMFDM-- 89
Cdd:TIGR01547 137 SNPESPLHWVykrfIENMEDEFRICIIHSTYRDNPFLSEVTIQEIEELKRRDPALYRRIWLGEWVSALgGILYKKLDVka 216

                  ....*...
gi 2482172056  90 --DKNIQH 95
Cdd:TIGR01547 217 ayIKESPN 224
 
Name Accession Description Interval E-value
phage_term_2 TIGR01547
phage terminase, large subunit, PBSX family; This model detects members of a highly divergent ...
17-95 1.78e-13

phage terminase, large subunit, PBSX family; This model detects members of a highly divergent family of the large subunit of phage terminase. All members are encoded by phage genomes or within prophage regions of bacterial genomes. This is a distinct family from pfam03354. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 273684 [Multi-domain]  Cd Length: 394  Bit Score: 64.35  E-value: 1.78e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482172056  17 LNSPAPNHPV----ISEVFDVQNTRWTHWTPNDNPILSEQRKQEIHEVFPKNPYLLERDWYGKRVMPQ-GVIYSMFDM-- 89
Cdd:TIGR01547 137 SNPESPLHWVykrfIENMEDEFRICIIHSTYRDNPFLSEVTIQEIEELKRRDPALYRRIWLGEWVSALgGILYKKLDVka 216

                  ....*...
gi 2482172056  90 --DKNIQH 95
Cdd:TIGR01547 217 ayIKESPN 224
XtmB COG1783
Phage terminase large subunit [Mobilome: prophages, transposons];
7-88 2.40e-04

Phage terminase large subunit [Mobilome: prophages, transposons];


Pssm-ID: 441389 [Multi-domain]  Cd Length: 408  Bit Score: 38.38  E-value: 2.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482172056   7 RCSGPLSFSRL----NSPAPNHPVISEVFDVQ---NTRWTHWTPNDNPILSEQRKQEIHEVFPKNPYLLERDWYGKRVMP 79
Cdd:COG1783   144 TLRGPGLFSEIwftfNPESPYHWVYKRFFDNEvppDTLVHHSTYLDNPFLPEQLIREIEDLKETDPDYYRHIWLGEWVGS 223

                  ....*....
gi 2482172056  80 QGVIYSMFD 88
Cdd:COG1783   224 EGLVFPNWE 232
 
Name Accession Description Interval E-value
phage_term_2 TIGR01547
phage terminase, large subunit, PBSX family; This model detects members of a highly divergent ...
17-95 1.78e-13

phage terminase, large subunit, PBSX family; This model detects members of a highly divergent family of the large subunit of phage terminase. All members are encoded by phage genomes or within prophage regions of bacterial genomes. This is a distinct family from pfam03354. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 273684 [Multi-domain]  Cd Length: 394  Bit Score: 64.35  E-value: 1.78e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482172056  17 LNSPAPNHPV----ISEVFDVQNTRWTHWTPNDNPILSEQRKQEIHEVFPKNPYLLERDWYGKRVMPQ-GVIYSMFDM-- 89
Cdd:TIGR01547 137 SNPESPLHWVykrfIENMEDEFRICIIHSTYRDNPFLSEVTIQEIEELKRRDPALYRRIWLGEWVSALgGILYKKLDVka 216

                  ....*...
gi 2482172056  90 --DKNIQH 95
Cdd:TIGR01547 217 ayIKESPN 224
XtmB COG1783
Phage terminase large subunit [Mobilome: prophages, transposons];
7-88 2.40e-04

Phage terminase large subunit [Mobilome: prophages, transposons];


Pssm-ID: 441389 [Multi-domain]  Cd Length: 408  Bit Score: 38.38  E-value: 2.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482172056   7 RCSGPLSFSRL----NSPAPNHPVISEVFDVQ---NTRWTHWTPNDNPILSEQRKQEIHEVFPKNPYLLERDWYGKRVMP 79
Cdd:COG1783   144 TLRGPGLFSEIwftfNPESPYHWVYKRFFDNEvppDTLVHHSTYLDNPFLPEQLIREIEDLKETDPDYYRHIWLGEWVGS 223

                  ....*....
gi 2482172056  80 QGVIYSMFD 88
Cdd:COG1783   224 EGLVFPNWE 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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